43210-67-9 | methyl N-[5-(phenylsulfanyl)-1H-1,3-benzodiazol-2-yl]carbamate

Packsize	Purity	Availability	Price	Discounted Price
100mg	98+%	in stock	$6.00	$4.00
1g	98+%	in stock	$10.00	$7.00
5g	98+%	in stock	$18.00	$13.00
10g	98+%	in stock	$29.00	$20.00
25g	98+%	in stock	$53.00	$37.00
100g	98+%	in stock	$151.00	$106.00
500g	98+%	in stock	$566.00	$396.00

Description

• Catalog Number: AB51820
• Chemical Name: methyl N-[5-(phenylsulfanyl)-1H-1,3-benzodiazol-2-yl]carbamate
• CAS Number: 43210-67-9
• Molecular Formula: C15H13N3O2S
• Molecular Weight: 299.3476
• MDL Number: MFCD00144301
• SMILES: COC(=O)Nc1nc2c([nH]1)cc(cc2)Sc1ccccc1
• NSC Number: 757824

Computed Properties

• Complexity: 363
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 21
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 4
• XLogP3: 3.6

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  Veterinary parasitology 20070315

• Efficacy of fenbendazole and milbemycin oxime for treating baboons (Papio cynocephalus anubis) infected with Trichuris trichiura.

  Journal of the American Association for Laboratory Animal Science : JAALAS 20070301

• Survey of intestinal parasites in stray dogs in the Madrid area and comparison of the efficacy of three anthelmintics in naturally infected dogs.

  Parasitology research 20070101

• A field study on the effect of some anthelmintics on cyathostomins of horses in sweden.

  Veterinary research communications 20070101

• Angiostrongylus vasorum (French heartworm) in a dog imported into Australia.

  Australian veterinary journal 20070101

• A longitudinal study on the occurrence of Cryptosporidium and Giardia in dogs during their first year of life.

  Acta veterinaria Scandinavica 20070101

• Evaluation of follow-up of therapy with fenbendazole incorporated into stabilized liposomes and immunomodulator glucan in mice infected with Toxocara canis larvae.

  Acta tropica 20070101

• Strongyloides stercoralis infection in a Finnish kennel.

  Acta veterinaria Scandinavica 20070101

• Field testing of a fenbendazole treatment combined with hygienic and management measures against a natural Giardia infection in calves.

  Veterinary parasitology 20061220

• Severe weight loss in lambs infected with Giardia duodenalis assemblage B.

  Veterinary parasitology 20061130

• Survey of parasite control on beef farms in south-west England.

  The Veterinary record 20061111

• Fenbendazole treatment and litter size in rats.

  Journal of the American Association for Laboratory Animal Science : JAALAS 20061101

• Mortality associated with fenbendazole administration in pigeons (Columba livia).

  Journal of the American Association for Laboratory Animal Science : JAALAS 20061101

• Canine intestinal helminths in Finland: prevalence, risk factors and endoparasite control practices.

  Veterinary parasitology 20060910

• Changes in parasite transmission stage excretion after pheasant release.

  Journal of helminthology 20060901

• Acquired cervical scoliosis attributed to Parelaphostrongylus tenuis infection in an alpaca.

  Journal of the American Veterinary Medical Association 20060815

• A fenbendazole oral drench in addition to an ivermectin pour-on reduces parasite burden and improves feedlot and carcass performance of finishing heifers compared with endectocides alone.

  Journal of animal science 20060801

• Ecological hazard assessment of major veterinary benzimidazoles: acute and chronic toxicities to aquatic microbes and invertebrates.

  Environmental toxicology and chemistry 20060801

• Severe pulmonary arterial hypertension due to Angiostrongylosus vasorum in a dog.

  The Canadian veterinary journal = La revue veterinaire canadienne 20060801

• Plasma disposition and faecal excretion of oxfendazole, fenbendazole and albendazole following oral administration to donkeys.

  Veterinary journal (London, England : 1997) 20060701

• Small strongyle infection: consequences of larvicidal treatment of horses with fenbendazole and moxidectin.

  Veterinary parasitology 20060630

• Control of gastrointestinal nematodes in goats on pastures in South Africa using nematophagous fungi Duddingtonia flagrans and selective anthelmintic treatments.

  Veterinary parasitology 20060615

• Modulation of porcine biotransformation enzymes by anthelmintic therapy with fenbendazole and flubendazole.

  Research in veterinary science 20060601

• Assessment of the main metabolism pathways for the flukicidal compound triclabendazole in sheep.

  Journal of veterinary pharmacology and therapeutics 20060601

• Prevalence of Escherichia coli O157:H7 and Salmonella in beef steers consuming different forage diets.

  Letters in applied microbiology 20060601

• Photo- and thermal-stability studies on benzimidazole anthelmintics by HPLC and GC-MS.

  Chemical & pharmaceutical bulletin 20060601

• Gastrointestinal nematode resistance to benzimidazoles on a sheep farm in Algeria.

  The Veterinary record 20060506

• Drug transport mechanisms in helminth parasites: passive diffusion of benzimidazole anthelmintics.

  Experimental parasitology 20060501

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• Anthelmintic use and resistance on thoroughbred training yards in the UK.

  The Veterinary record 20060429

• Presumptive fenbendazole toxicosis in North American porcupines.

  Journal of the American Veterinary Medical Association 20060415

• Comparative study of sample preparation methods; supported liquid membrane and solid phase extraction in the determination of benzimidazole anthelmintics in biological matrices by liquid chromatography-electrospray-mass spectrometry.

  Talanta 20060315

• Immunomodulatory effect of various anti-parasitics: a review.

  Parasitology 20060301

• Prophylactic fenbendazole therapy does not affect the incidence and onset of type 1 diabetes in non-obese diabetic mice.

  International immunology 20060301

• Evaluation of three strategic parasite control programs in captive wild ruminants.

  Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians 20060301

• Effect of parasitism on the pharmacokinetic disposition of ivermectin in lambs.

  Journal of veterinary medicine. A, Physiology, pathology, clinical medicine 20060201

• Metal-mediated inhibition of Escherichia coli methionine aminopeptidase: structure-activity relationships and development of a novel scoring function for metal-ligand interactions.

  Journal of medicinal chemistry 20060126

• Pharmacologic reductions of total tau levels; implications for the role of microtubule dynamics in regulating tau expression.

  Molecular neurodegeneration 20060101

• Meningoencephalomyelitis caused by Pasteurella multocida in a cat.

  Journal of veterinary internal medicine 20060101

• Comparing different formulae to test for gastrointestinal nematode resistance to benzimidazoles in smallholder goat farms in Mexico.

  Veterinary parasitology 20051210

• Further characterisation of a triple resistant field isolate of Teladorsagia from a Scottish lowland sheep farm.

  Veterinary parasitology 20051210

• Evaluation of silymarin in the treatment on asymptomatic Giardia infections in dogs.

  Parasitology research 20051201

• Hematologic and plasma biochemical changes associated with fenbendazole administration in Hermann's tortoises (testudo hermanni).

  Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians 20051201

• Aelurostrongylus abstrusus (cat lungworm) infection in five cats from Italy.

  Veterinary parasitology 20051125

• Field evaluation of the efficacy of fenbendazole in captive wild ruminants.

  The Veterinary record 20051105

• Verminous pneumonia due to Filaroides hirthi in a Scottish terrier in Spain.

  The Veterinary record 20051105

• A 12-month survey of gastrointestinal helminth infections of cervids kept in two zoos in Belgium.

  Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians 20050901

• Transport of anthelmintic benzimidazole drugs by breast cancer resistance protein (BCRP/ABCG2).

  Drug metabolism and disposition: the biological fate of chemicals 20050501

• Changes to oxfendazole chiral kinetics and anthelmintic efficacy induced by piperonyl butoxide in horses.

  Equine veterinary journal 20050501

• Thrombo-ischaemic pinnal necrosis associated with fenbendazole treatment in a dog.

  The Journal of small animal practice 20050501

• Individual intake and antiparasitic efficacy of free choice mineral containing fenbendazole for grazing steers.

  Veterinary parasitology 20050420

• Microbial inhibition by pharmaceutical antibiotics in different soils--dose-response relations determined with the iron(III) reduction test.

  Environmental toxicology and chemistry 20050401

• Relationships among fecal lungworm loads, fecal glucocorticoid metabolites, and lamb recruitment in free-ranging Rocky Mountain bighorn sheep.

  Journal of wildlife diseases 20050401

• Identification of strongyle eggs from anthelmintic-treated horses using a PCR-ELISA based on intergenic DNA sequences.

  Parasitology research 20050301

• The lack of behavioral effects of fenbendazole: a medication for pinworm infection.

  Contemporary topics in laboratory animal science 20050301

• Cerebral and conjunctival haemorrhages associated with von Willebrand factor deficiency and canine angiostrongylosis.

  The Journal of small animal practice 20050201

• Intracranial haemorrhage associated with Angiostrongylus vasorum infection in three dogs.

  The Journal of small animal practice 20050201

• Eradication of Syphacia muris from food-restricted rats without environmental decontamination.

  Contemporary topics in laboratory animal science 20050101

• Clinical, cytological and molecular evidence of Mesocestoides sp. infection in a dog from Italy.

  Journal of veterinary medicine. A, Physiology, pathology, clinical medicine 20041201

• Characterisation of benzimidazole binding with recombinant tubulin from Giardia duodenalis, Encephalitozoon intestinalis, and Cryptosporidium parvum.

  Molecular and biochemical parasitology 20041101

• Effect of the antiparasitic drugs fenbendazole and ivermectin on the soil nematode Pristionchus maupasi.

  Veterinary parasitology 20040920

• Prevalence of anthelmintic resistant cyathostomes on horse farms.

  Journal of the American Veterinary Medical Association 20040915

• Characterisation of two triple resistant field isolates of Teladorsagia from Scottish lowland sheep farms.

  Veterinary parasitology 20040902

• Effect of repeated benzimidazole treatments with increasing dosages on the phenotype of resistance and the beta-tubulin codon 200 genotype distribution in a benzimidazole-resistant cyathostomin population.

  Veterinary parasitology 20040902

• Angiostrongylus vasorum infection in 23 dogs (1999-2002).

  The Journal of small animal practice 20040901

• Variability in the resistance of the Nigerian West African Dwarf goat to abbreviated escalating trickle and challenge infections with Haemonchus contortus.

  Veterinary parasitology 20040610

• Comparative hepatic and extrahepatic enantioselective sulfoxidation of albendazole and fenbendazole in sheep and cattle.

  Drug metabolism and disposition: the biological fate of chemicals 20040501

• Radiographic findings in 16 dogs infected with Angiostrongylus vasorum.

  The Veterinary record 20040403

• Benzimidazole drugs and modulation of biotransformation enzymes.

  Research in veterinary science 20040401

• The effects of fenbendazole, flubendazole and mebendazole on activities of hepatic cytochromes P450 in pig.

  Journal of veterinary pharmacology and therapeutics 20040401

• Reversible pulmonary hypertension presenting simultaneously with an atrial septal defect and angiostrongylosis in a dog.

  The Journal of small animal practice 20040401

• Long-term results of dietary fenbendazole to eradicate Syphacia muris from rat colonies.

  Contemporary topics in laboratory animal science 20040301

• Prevalence of benzimidazole resistance on horse farms in Germany.

  The Veterinary record 20040110

• Comparative assessment of the access of albendazole, fenbendazole and triclabendazole to Fasciola hepatica: effect of bile in the incubation medium.

  Parasitology 20040101

• Bone marrow hypoplasia associated with fenbendazole administration in a dog.

  Journal of the American Animal Hospital Association 20040101

• Intestinal DNases of 36 and 38.5kDa from the parasitic nematode Haemonchus contortus have non-classic DNase characteristics and produce DNA fragments with 3'-hydroxyls.

  Experimental parasitology 20040101

• Evaluation of copper supplementation to control Haemonchus contortus infections of sheep in Sweden.

  Acta veterinaria Scandinavica 20040101

• Clinical signs, diagnosis and treatment of three dogs with angiostrongylosis in Ireland.

  Irish veterinary journal 20040101

• Quantitative chromatographic determination of several benzimidazole anthelmintic molecules in parasite material.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20031205

• Multiresistant nematodes on a Devon farm.

  The Veterinary record 20031108

• Field test data on small strongyles in evaluation of activity of fenbendazole given once a day for 5 consecutive days to thoroughbred yearlings on two farms in Kentucky in 2002 and 2003.

  Parasitology research 20031001

• Investigations on the influence of helminth parasites on vaccination of chickens against Newcastle disease virus under village conditions.

  Tropical animal health and production 20031001

• Anthelmintic resistance of nematodes in communally grazed goats in a semi-arid area of South Africa.

  Journal of the South African Veterinary Association 20030901

• Expulsion of small strongyle nematodes (cyathostomin spp) following deworming of horses on a stud farm in Sweden.

  Veterinary parasitology 20030814

• The effects of benzimidazole anthelmintics on P4501A in rat hepatocytes and HepG2 cells.

  Research in veterinary science 20030801

• Evaluation of fenbendazole for treatment of Giardia infection in cats concurrently infected with Cryptosporidium parvum.

  American journal of veterinary research 20030801

• A light and electron microscopic study on the synergistic effect of pyrantel and the febantel metabolite febendazole on adult Toxocara canis in vitro.

  Parasitology research 20030701

• Analysis of the beta-tubulin codon 200 genotype distribution in a benzimidazole-susceptible and -resistant cyathostome population.

  Parasitology 20030701

• Dexamethasone decreases plasma levels of the prochiral fenbendazole and its chiral and achiral metabolites in sheep.

  Xenobiotica; the fate of foreign compounds in biological systems 20030701

• Synergistic effects of pyrantel and the febantel metabolite fenbendazole on adult Toxocara canis.

  Parasitology research 20030701

• Dose confirmation of moxidectin 0.5% pour-on against adults and fourth-stage larvae of various Cooperia spp. and Trichostrongylus colubriformis in Louisiana.

  Veterinary parasitology 20030625

• Effect of feeding urea-molasses blocks with incorporated fenbendazole on grazing dairy heifers naturally infected with gastrointestinal nematodes.

  Journal of the South African Veterinary Association 20030601

• Anthelmintic treatment in horses: the extra-label use of products and the danger of under-dosing.

  Journal of the South African Veterinary Association 20030601

• Management of drug-resistant cyathostominosis on a breeding farm in central North Carolina.

  Equine veterinary journal 20030501

• Comparison of in vitro methods and faecal egg count reduction test for the detection of benzimidazole resistance in small strongyles of horses.

  Veterinary research communications 20030501

• Encephalitozoon cuniculi in pet rabbits.

  The Veterinary record 20030405

• Transtegumental diffusion of benzimidazole anthelmintics into Moniezia benedeni: correlation with their octanol-water partition coefficients.

  Experimental parasitology 20030101

• [Morphofunctional changes in the digestive system of the nematode Passalurus ambiguus (Rudolphi, 1819) after use of the anthelmintics albendazole, fenbendazole, and ivermectin].

  Meditsinskaia parazitologiia i parazitarnye bolezni 20030101

• Non-classic characteristics define prominent DNase activities from the intestine and other tissues of Haemonchus contortus.

  Experimental parasitology 20030101

• Disintegration of dung pats from cattle treated with the ivermectin anthelmintic bolus, or the biocontrol agent Duddingtonia flagrans.

  Acta veterinaria Scandinavica 20030101

• Experimental life cycle of Lagochilascaris major leiper, 1910 (Nematoda: Ascarididae) in cats (Felis domesticus).

  The Journal of parasitology 20021201

• Interspecies considerations in the evaluation of human food safety for veterinary drugs.

  AAPS pharmSci 20021201

• Lack of modification of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx)-induced hepatocarcinogenesis in rats by fenbendazole--a CYP1A2 inducer.

  Cancer letters 20021108

• Development and validation of a liquid chromatographic-electrospray tandem mass spectrometric multiresidue method for anthelmintics in milk.

  Journal of chromatography. A 20021108

• Fenbendazole pharmacokinetics, metabolism, and potentiation in horses.

  Drug metabolism and disposition: the biological fate of chemicals 20021101

• Analysis of fenbendazole residues in bovine milk by ELISA.

  Journal of agricultural and food chemistry 20021009

• Equine faecal egg counts and comparison of fenbendazole and moxidectin.

  The Veterinary record 20020928

• Comparative use of faecal egg count reduction test, egg hatch assay and beta-tubulin codon 200 genotyping in small strongyles (cyathostominae) before and after benzimidazole treatment.

  Veterinary parasitology 20020926

• Voltammetric determination of fenbendazole in veterinarian formulations.

  Journal of pharmaceutical and biomedical analysis 20020905

• A survey on the occurrence of resistance to anthelmintics of gastrointestinal nematodes of goats in Mozambique.

  The Onderstepoort journal of veterinary research 20020901

• Patterns of equine faecal egg counts following spring dosing with either fenbendazole or moxidectin.

  The Veterinary record 20020831

• Bone marrow hypoplasia and intestinal crypt cell necrosis associated with fenbendazole administration in five painted storks.

  Journal of the American Veterinary Medical Association 20020801

• In vitro activity of therapeutic drugs against Histomonas meleagridis (Smith, 1895).

  Poultry science 20020801

• Distinct characteristics of two intestinal protein compartments discriminated by using fenbendazole and a benzimidazole resistant isolate of Haemonchus contortus.

  Experimental parasitology 20020801

• [Bladder infection with Capillaria plica in a male dog].

  Tijdschrift voor diergeneeskunde 20020615

• A questionnaire survey of the management and use of anthelmintics in cattle and antelope in mixed farming systems in Zimbabwe.

  Journal of the South African Veterinary Association 20020601

• A retrospective study of 11 cases of lungworm (Didelphostrongylus hayesi) infection in opossums (Didelphis virginiana).

  Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians 20020601

• Determination of benzimidazole anthelmintics in animal-derived biological matrices.

  Annali di chimica 20020401

• Expression of acquired immunity to a local isolate of Haemonchus contortus by the Nigerian West African Dwarf goat.

  Veterinary parasitology 20020320

• Plasma achiral and chiral pharmacokinetic behaviour of intravenous oxfendazole co-administered with piperonyl butoxide in sheep.

  Journal of veterinary pharmacology and therapeutics 20020201

• In vitro ruminal biotransformation of benzimidazole sulphoxide anthelmintics: enantioselective sulphoreduction in sheep and cattle.

  Journal of veterinary pharmacology and therapeutics 20020201

• Characteristics of a flubendazole resistant isolate of Oesophagostomum dentatum from Germany.

  Veterinary parasitology 20020103

• Subclinical effects and fenbendazole treatment of turkey ascaridiasis under simulated field conditions.

  Avian diseases 20020101

• High-performance liquid chromatographic separation and determination of the process related impurities of mebendazole, fenbendazole and albendazole in bulk drugs.

  Journal of pharmaceutical and biomedical analysis 20011201

• New sesquiterpene derivatives from the red alga Laurencia scoparia. Isolation, structure determination, and anthelmintic activity.

  Journal of natural products 20011201

• Prevalence of anthelmintic resistance in gastrointestinal nematodes of dairy goats under extensive management conditions in southwestern France.

  Journal of helminthology 20011201

• Cyathostome fecal egg count trends in horses treated with moxidectin, ivermectin or fenbendazole.

  Veterinary parasitology 20011031

• Comparison of practical treatment methods to eradicate pinworm (Dentostomella translucida) infections from Mongolian gerbils (Meroines unguiculatus).

  Contemporary topics in laboratory animal science 20010901

• Are Teladorsagia circumcincta (Nematoda) morphs equally able to survive under anthelmintic treatment in sheep on pastures?

  Parasitology research 20010901

• Effect of benzimidazole under-dosing on the resistant allele frequency in Teladorsagia circumcincta (Nematoda).

  Parasitology 20010701

• Anthelmintic resistance on goat farms in Georgia: efficacy of anthelmintics against gastrointestinal nematodes in two selected goat herds.

  Veterinary parasitology 20010628

• Prevalence and clinical implications of anthelmintic resistance in cyathostomes of horses.

  Journal of the American Veterinary Medical Association 20010615

• Resistance of Cooperia to ivermectin treatments in grazing cattle of the Humid Pampa, Argentina.

  Veterinary parasitology 20010612

• Treatment of Toxocara canis infections in mice with liposome-incorporated benzimidazole carbamates and immunomodulator glucan.

  Journal of helminthology 20010601

• Prevention and treatment of Encephalitozoon cuniculi infection in rabbits with fenbendazole.

  The Veterinary record 20010414

• Intestinal parasitism terminates self tolerance and enhances neonatal induction of autoimmune disease and memory.

  European journal of immunology 20010301

• Transmission studies on Trichinella species isolated from Crocodylus niloticus and efficacy of fenbendazole and levamisole against muscle L1 stages in Balb C mice.

  The Onderstepoort journal of veterinary research 20010301

• Individual intake and antiparasitic efficacy of free choice mineral and fenbendazole in range calves.

  Veterinary parasitology 20010101

• Giardiasis in dairy calves: effects of fenbendazole treatment on intestinal structure and function.

  International journal for parasitology 20010101

• Atypical parasitic migration and necrotizing sacral myelitis due to Serratospiculoides amaculata in a prairie falcon (Falco mexicanus).

  Avian diseases 20010101

• Elevated parathyroid hormone-related protein and hypercalcemia in two dogs with schistosomiasis.

  Journal of the American Animal Hospital Association 20010101

• Housing, feeding and management of calves and replacement heifers in Swedish dairy herds.

  Acta veterinaria Scandinavica 20010101

• In vitro susceptibilities of the AIDS-associated microsporidian Encephalitozoon intestinalis to albendazole, its sulfoxide metabolite, and 12 additional benzimidazole derivatives.

  Antimicrobial agents and chemotherapy 19971201

• Efficacy of 101 antimicrobials and other agents on the development of Cryptosporidium parvum in vitro.

  Annals of tropical medicine and parasitology 19961201

• New drug developments for opportunistic infections in immunosuppressed patients: Pneumocystis carinii.

  Journal of medicinal chemistry 19951124

• In vitro susceptibility of the opportunistic fungus Cryptococcus neoformans to anthelmintic benzimidazoles.

  Antimicrobial agents and chemotherapy 19940201

• Aplastic anemia associated with trimethoprim-sulfadiazine and fenbendazole administration in a dog.

  Journal of the American Veterinary Medical Association 19871101