4347-33-5 | 5-Formylthiophene-2-boronic acid

Packsize	Purity	Availability	Price	Discounted Price
5g	98%	in stock	$11.00	$8.00
10g	98%	in stock	$21.00	$15.00
25g	98%	in stock	$42.00	$30.00
100g	98%	in stock	$167.00	$117.00

Description

• Catalog Number: AD31413
• Chemical Name: 5-Formylthiophene-2-boronic acid
• CAS Number: 4347-33-5
• Molecular Formula: C5H5BO3S
• Molecular Weight: 155.9674
• MDL Number: MFCD02093666
• SMILES: O=Cc1ccc(s1)B(O)O

Computed Properties

• Complexity: 130
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 10
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 2

Upstream Synthesis Route

5-Formylthiophen-2-boronic acid, also known as $name$, serves as a versatile building block in chemical synthesis. This compound is commonly utilized in the area of organic chemistry for its ability to participate in various reactions, particularly in the formation of carbon-carbon and carbon-heteroatom bonds.One key application of 5-Formylthiophen-2-boronic acid is in Suzuki-Miyaura cross-coupling reactions. By reacting with aryl halides or pseudohalides in the presence of a palladium catalyst, this compound can be used to form biaryl compounds. This reaction is highly valuable in the synthesis of pharmaceuticals, agrochemicals, and materials science.Furthermore, 5-Formylthiophen-2-boronic acid can also undergo further functionalization to introduce additional groups or moieties, enabling the synthesis of complex organic molecules. Its aldehyde functional group provides opportunities for selective derivatization, allowing chemists to tailor the structure of the final product for specific applications.Overall, the versatility and reactivity of 5-Formylthiophen-2-boronic acid make it a valuable tool in the toolbox of synthetic chemists, enabling the construction of diverse and intricate molecular architectures for various industries and research fields.

Literature

• Synthesis and evaluation of 3-(dihydroxyboryl)benzoic acids as D,D-carboxypeptidase R39 inhibitors.

  Journal of medicinal chemistry 20091008

• Coupling reaction on gold nanoparticle to yield polythiophene/gold nanoparticle alternate network film.

  Journal of nanoscience and nanotechnology 20090101