4376-20-9 | 2-(((2-Ethylhexyl)oxy)carbonyl)benzoic acid

Packsize	Purity	Availability	Price	Discounted Price
100mg	95%	in stock	$13.00	$9.00
250mg	95%	in stock	$16.00	$11.00
1g	95%	in stock	$29.00	$20.00
10g	95%	in stock	$261.00	$183.00
25g	95%	in stock	$619.00	$433.00

Description

• Catalog Number: AB43447
• Chemical Name: 2-(((2-Ethylhexyl)oxy)carbonyl)benzoic acid
• CAS Number: 4376-20-9
• Molecular Formula: C16H22O4
• Molecular Weight: 278.3435
• MDL Number: MFCD00041500
• SMILES: CCCCC(COC(=O)c1ccccc1C(=O)O)CC

Computed Properties

• Complexity: 314
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 20
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 9
• Undefined Atom Stereocenter Count: 1
• XLogP3: 4

Literature

• MEHP and MEOHP but not DEHP bind productively to the peroxisome proliferator-activated receptor γ.

  Rapid communications in mass spectrometry : RCM 20180807

• Placental lncRNA Expression Is Associated With Prenatal Phthalate Exposure.

  Toxicological sciences : an official journal of the Society of Toxicology 20180501

• An Investigation of the Single and Combined Phthalate Metabolite Effects on Human Chorionic Gonadotropin Expression in Placental Cells.

  Environmental health perspectives 20171001

• Agonistic and antagonistic effects of phthalates and their urinary metabolites on the steroid hormone receptors ERα, ERβ, and AR.

  Toxicology letters 20170805

• Mono-2-ethylhexyl phthalate inhibits human extravillous trophoblast invasion via the PPARγ pathway.

  Toxicology and applied pharmacology 20170715

• Effects of DEHP and its metabolite MEHP on insulin signalling and proteins involved in GLUT4 translocation in cultured L6 myotubes.

  Toxicology 20170701

• Promotion of Wilms' tumor cells migration and invasion by mono-2-ethyhexyl phthalate (MEHP) via activation of NF-κB signals.

  Chemico-biological interactions 20170525

• Activation of Peroxisome Proliferator-Activated Receptor Gamma and Disruption of Progesterone Synthesis of 2-Ethylhexyl Diphenyl Phosphate in Human Placental Choriocarcinoma Cells: Comparison with Triphenyl Phosphate.

  Environmental science & technology 20170404

• Monoethylhexyl Phthalate Elicits an Inflammatory Response in Adipocytes Characterized by Alterations in Lipid and Cytokine Pathways.

  Environmental health perspectives 20170401

• Mono-(2-ethylhexyl) phthalate-induced Sertoli cell injury stimulates the production of pro-inflammatory cytokines in Fischer 344 rats.

  Reproductive toxicology (Elmsford, N.Y.) 20170401

• Low level of mono(2-ethylhexyl) phthalate reduces oocyte developmental competence in association with impaired gene expression.

  Toxicology 20170215

• Glucuronidation of mono(2-ethylhexyl) phthalate in humans: roles of hepatic and intestinal UDP-glucuronosyltransferases.

  Archives of toxicology 20170201

• Maternal urinary phthalates and sex-specific placental mRNA levels in an urban birth cohort.

  Environmental health : a global access science source 20170101

• Activation of the Constitutive Androstane Receptor by Monophthalates.

  Chemical research in toxicology 20161017

• Environmental Chemicals Modulate Polar Bear (Ursus maritimus) Peroxisome Proliferator-Activated Receptor Gamma (PPARG) and Adipogenesis in Vitro.

  Environmental science & technology 20161004

• Mono-2-ethylhexyl phthalate disrupts neurulation and modifies the embryonic redox environment and gene expression.

  Reproductive toxicology (Elmsford, N.Y.) 20160801

• Stimulatory effects of combined endocrine disruptors on MA-10 Leydig cell steroid production and lipid homeostasis.

  Toxicology 20160429

• Mono-2-ethyhexyl phthalate advancing the progression of prostate cancer through activating the hedgehog pathway in LNCaP cells.

  Toxicology in vitro : an international journal published in association with BIBRA 20160401

• Mono(2-ethylhexyl)phthalate accumulation disturbs energy metabolism of fat cells.

  Archives of toxicology 20160301

• Mono-(2-ethylhexyl) phthalate induces apoptosis through miR-16 in human first trimester placental cell line HTR-8/SVneo.

  Toxicology in vitro : an international journal published in association with BIBRA 20160301

• Cytochrome P450-inhibitory activity of parabens and phthalates used in consumer products.

  The Journal of toxicological sciences 20160101

• Mono(2-ethylhexyl) phthalate induces apoptosis in p53-silenced L02 cells via activation of both mitochondrial and death receptor pathways.

  Environmental toxicology 20150901

• Activation of Human Peroxisome Proliferator-Activated Nuclear Receptors (PPARγ1) by Semi-Volatile Compounds (SVOCs) and Chemical Mixtures in Indoor Dust.

  Environmental science & technology 20150818

• Effects of mono(2-ethylhexyl)phthalate on cytoplasmic maturation of oocytes--The bovine model.

  Reproductive toxicology (Elmsford, N.Y.) 20150601

• Structurally-diverse, PPARγ-activating environmental toxicants induce adipogenesis and suppress osteogenesis in bone marrow mesenchymal stromal cells.

  Toxicology 20150504

• Population-based in vitro hazard and concentration-response assessment of chemicals: the 1000 genomes high-throughput screening study.

  Environmental health perspectives 20150501

• Mono-2-ethylhexyl phthalate stimulates androgen production but suppresses mitochondrial function in mouse leydig cells with different steroidogenic potential.

  Toxicological sciences : an official journal of the Society of Toxicology 20150501

• Prenatal and peripubertal phthalates and bisphenol A in relation to sex hormones and puberty in boys.

  Reproductive toxicology (Elmsford, N.Y.) 20140801

• Phthalates efficiently bind to human peroxisome proliferator activated receptor and retinoid X receptor α, β, γ subtypes: an in silico approach.

  Journal of applied toxicology : JAT 20140701

• Co-treatment of mouse antral follicles with 17β-estradiol interferes with mono-2-ethylhexyl phthalate (MEHP)-induced atresia and altered apoptosis gene expression.

  Reproductive toxicology (Elmsford, N.Y.) 20140601

• Associations of filaggrin gene loss-of-function variants with urinary phthalate metabolites and testicular function in young Danish Men.

  Environmental health perspectives 20140401

• Transcriptome-based functional classifiers for direct immunotoxicity.

  Archives of toxicology 20140301

• Case-control study of breast cancer and exposure to synthetic environmental chemicals among Alaska Native women.

  International journal of circumpolar health 20140101

• Human urinary phthalate metabolites level and main semen parameters, sperm chromatin structure, sperm aneuploidy and reproductive hormones.

  Reproductive toxicology (Elmsford, N.Y.) 20131201

• In vitro intestinal and hepatic metabolism of Di(2-ethylhexyl) phthalate (DEHP) in human and rat.

  Toxicology in vitro : an international journal published in association with BIBRA 20130801

• Mono-2-ethylhexyl phthalate induces oxidative stress responses in human placental cells in vitro.

  Toxicology and applied pharmacology 20130401

• The endocrine disruptor mono-(2-ethylhexyl) phthalate promotes adipocyte differentiation and induces obesity in mice.

  Bioscience reports 20121201

• Effect of di-(2-ethylhexyl) phthalate and mono-(2-ethylhexyl) phthalate on in vitro developmental competence of bovine oocytes.

  Cell biology and toxicology 20121201

• Expressing urine from a gel disposable diaper for biomonitoring using phthalates as an example.

  Journal of exposure science & environmental epidemiology 20121101

• Hydrolysis of di-n-butyl phthalate, butylbenzyl phthalate and di(2-ethylhexyl) phthalate in human liver microsomes.

  Chemosphere 20121101

• Kinetics of di(2-ethylhexyl) phthalate (DEHP) and mono(2-ethylhexyl) phthalate in blood and of DEHP metabolites in urine of male volunteers after single ingestion of ring-deuterated DEHP.

  Toxicology and applied pharmacology 20121015

• Phthalate excretion pattern and testicular function: a study of 881 healthy Danish men.

  Environmental health perspectives 20121001

• Dose-response analysis of phthalate effects on gene expression in rat whole embryo culture.

  Toxicology and applied pharmacology 20121001

• Mono-(2-ethylhexyl)-phthalate (MEHP) affects ERK-dependent GDNF signalling in mouse stem-progenitor spermatogonia.

  Toxicology 20120904

• Mono-(2-ethylhexyl) phthalate affects the steroidogenesis in rat Leydig cells through provoking ROS perturbation.

  Toxicology in vitro : an international journal published in association with BIBRA 20120901

• Simultaneous determination of multiple phthalate metabolites and bisphenol-A in human urine by liquid chromatography-tandem mass spectrometry.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120901

• Reproductive effects in F1 adult females exposed in utero to moderate to high doses of mono-2-ethylhexylphthalate (MEHP).

  Reproductive toxicology (Elmsford, N.Y.) 20120801

• Compound-specific effects of diverse neurodevelopmental toxicants on global gene expression in the neural embryonic stem cell test (ESTn).

  Toxicology and applied pharmacology 20120801

• Phthalates exposure of Chinese reproductive age couples and its effect on male semen quality, a primary study.

  Environment international 20120701

• Urinary phthalate metabolites and their biotransformation products: predictors and temporal variability among men and women.

  Journal of exposure science & environmental epidemiology 20120701

• Circulating levels of phthalate metabolites are associated with prevalent diabetes in the elderly.

  Diabetes care 20120701

• MEHP-induced oxidative DNA damage and apoptosis in HepG2 cells correlates with p53-mediated mitochondria-dependent signaling pathway.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120701

• Foetal exposure to phthalate esters and anogenital distance in male newborns.

  International journal of andrology 20120601

• Predicted risk of childhood allergy, asthma, and reported symptoms using measured phthalate exposure in dust and urine.

  Indoor air 20120601

• Associations between circulating levels of bisphenol A and phthalate metabolites and coronary risk in the elderly.

  Ecotoxicology and environmental safety 20120601

• BLTK1 murine Leydig cells: a novel steroidogenic model for evaluating the effects of reproductive and developmental toxicants.

  Toxicological sciences : an official journal of the Society of Toxicology 20120601

• Effect of mono-(2-ethylhexyl) phthalate on human and mouse fetal testis: In vitro and in vivo approaches.

  Toxicology and applied pharmacology 20120515

• Effects of di-(2-ethylhexyl) phthalate and four of its metabolites on steroidogenesis in MA-10 cells.

  Ecotoxicology and environmental safety 20120501

• Variability of urinary phthalate metabolite and bisphenol A concentrations before and during pregnancy.

  Environmental health perspectives 20120501

• Mono-(2-ethylhexyl) phthalate (MEHP) promotes invasion and migration of human testicular embryonal carcinoma cells.

  Biology of reproduction 20120501

• Mono-2-ethylhexyl phthalate induced loss of mitochondrial membrane potential and activation of Caspase3 in HepG2 cells.

  Environmental toxicology and pharmacology 20120501

• Human testis steroidogenesis is inhibited by phthalates.

  Human reproduction (Oxford, England) 20120501

• Differences in metabolite burden of di(2-ethylhexyl)phthalate in pregnant and postpartum dams and their offspring in relation to drug-metabolizing enzymes in mice.

  Archives of toxicology 20120401

• Plasticizers excreted in urine: indication of autologous blood transfusion in sports.

  Transfusion 20120301

• Exposure to phthalates and phenols during pregnancy and offspring size at birth.

  Environmental health perspectives 20120301

• Association between pregnancy loss and urinary phthalate levels around the time of conception.

  Environmental health perspectives 20120301

• In vitro metabolism of di(2-ethylhexyl) phthalate (DEHP) by various tissues and cytochrome P450s of human and rat.

  Toxicology in vitro : an international journal published in association with BIBRA 20120301

• Mono-2-ethylhexylphthalate (MEHP) induces TNF-α release and macrophage differentiation through different signalling pathways in RAW264.7 cells.

  Toxicology letters 20120225

• Phthalate esters modulate the differentiation and maturation of mouse peripheral blood mononuclear cell-derived dendritic cells.

  Journal of applied toxicology : JAT 20120201

• Maternal prenatal urinary phthalate metabolite concentrations and child mental, psychomotor, and behavioral development at 3 years of age.

  Environmental health perspectives 20120201

• Acute airway irritation of methyl formate in mice.

  Archives of toxicology 20120201

• Di(2-ethylhexyl)phthalate and mono(2-ethylhexyl)phthalate in media for in vitro fertilization.

  Chemosphere 20120201

• Metabolism of di (2-ethylhexyl) phthalate (DEHP): comparative study in juvenile and fetal marmosets and rats.

  The Journal of toxicological sciences 20120201

• Inhibition of claudin-11 and occludin expression in rat Sertoli cells by mono-(2-ethylhexyl) phthalate through p44/42 mitogen-activated protein kinase pathway.

  Journal of andrology 20120101

• Circulating levels of bisphenol A (BPA) and phthalates in an elderly population in Sweden, based on the Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS).

  Ecotoxicology and environmental safety 20120101

• Feeding bottles usage and the prevalence of childhood allergy and asthma.

  Clinical & developmental immunology 20120101

• Di-(2-ethylhexyl) phthalate and autism spectrum disorders.

  ASN neuro 20120101

• Evaluation of ovarian toxicity of mono-(2-ethylhexyl) phthalate (MEHP) using cultured rat ovarian follicles.

  The Journal of toxicological sciences 20120101

• Contribution of environmental pollutants to male infertily: a working model of germ cell apoptosis induced by plasticizers.

  Biological research 20120101

• Pulmonary toxicity and adjuvant effect of di-(2-exylhexyl) phthalate in ovalbumin-immunized BALB/c mice.

  PloS one 20120101

• Phytochemical and biological studies of Agave attenuata.

  International journal of molecular sciences 20120101

• The association between some endocrine disruptors and hypospadias in biological samples.

  Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering 20120101

• Cellular and molecular effect of MEHP Involving LXRα in human fetal testis and ovary.

  PloS one 20120101

• Combined transcriptomic-(1)H NMR metabonomic study reveals that monoethylhexyl phthalate stimulates adipogenesis and glyceroneogenesis in human adipocytes.

  Journal of proteome research 20111202

• Transcriptional suppression of Sertoli cell Timp2 in rodents following mono-(2-ethylhexyl) phthalate exposure is regulated by CEBPA and MYC.

  Biology of reproduction 20111201

• Mitochondrial permeability and toxicity of diethylhexyl and monoethylhexyl phthalates on TK6 human lymphoblasts cells.

  Toxicology in vitro : an international journal published in association with BIBRA 20111201

• Trends of the internal phthalate exposure of young adults in Germany--follow-up of a retrospective human biomonitoring study.

  International journal of hygiene and environmental health 20111201

• Dissecting the phthalate-induced Sertoli cell injury: the fragile balance of proteases and their inhibitors.

  Biology of reproduction 20111201

• Consideration of dosimetry in evaluation of ToxCast™ data.

  Journal of applied toxicology : JAT 20111101

• In vitro effects of estradiol-17β, monobutyl phthalate and mono-(2-ethylhexyl) phthalate on the secretion of testosterone and insulin-like peptide 3 by interstitial cells of scrotal and retained testes in dogs.

  Theriogenology 20111015

• Relationship between urinary phthalate and bisphenol A concentrations and serum thyroid measures in U.S. adults and adolescents from the National Health and Nutrition Examination Survey (NHANES) 2007-2008.

  Environmental health perspectives 20111001

• Sensitive bioassay for detection of PPARα potentially hazardous ligands with gold nanoparticle probe.

  Journal of hazardous materials 20110915

• Peroxisome proliferator-activated receptor γ is a target for halogenated analogs of bisphenol A.

  Environmental health perspectives 20110901

• Circulating levels of bisphenol A and phthalates are related to carotid atherosclerosis in the elderly.

  Atherosclerosis 20110901

• Associations between urinary metabolites of di(2-ethylhexyl) phthalate and reproductive hormones in fertile men.

  International journal of andrology 20110801

• Rapid determination of urinary di(2-ethylhexyl) phthalate metabolites based on liquid chromatography/tandem mass spectrometry as a marker for blood transfusion in sports drug testing.

  Analytical and bioanalytical chemistry 20110801

• Case report: high prenatal bisphenol a exposure and infant neonatal neurobehavior.

  Environmental health perspectives 20110801

• Urinary phthalate metabolites in relation to biomarkers of inflammation and oxidative stress: NHANES 1999-2006.

  Environmental research 20110701

• Personal care product use and urinary levels of phthalate metabolites in Mexican women.

  Environment international 20110701

• Food packaging and bisphenol A and bis(2-ethyhexyl) phthalate exposure: findings from a dietary intervention.

  Environmental health perspectives 20110701

• Induction of ROS, p53, p21 in DEHP- and MEHP-exposed LNCaP cells-protection by selenium compounds.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110701

• Biological monitoring of exposure to di(2-ethylhexyl) phthalate in six French factories: a field study.

  International archives of occupational and environmental health 20110601

• Environmental chemicals in pregnant women in the United States: NHANES 2003-2004.

  Environmental health perspectives 20110601

• Associations between maternal phthalate exposure and cord sex hormones in human infants.

  Chemosphere 20110501

• Many putative endocrine disruptors inhibit prostaglandin synthesis.

  Environmental health perspectives 20110401

• Discriminating classes of developmental toxicants using gene expression profiling in the embryonic stem cell test.

  Toxicology letters 20110305

• Phthalates: toxicogenomics and inferred human diseases.

  Genomics 20110301

• Mono-(2-ethylhexyl) phthalate impairs neurodevelopment: inhibition of proliferation and promotion of differentiation in PC12 cells.

  Toxicology letters 20110225

• Present state and future perspectives of using pluripotent stem cells in toxicology research.

  Archives of toxicology 20110201

• Increased plasma levels of phthalate esters in women with advanced-stage endometriosis: a prospective case-control study.

  Fertility and sterility 20110101

• Variability and predictors of urinary bisphenol A concentrations during pregnancy.

  Environmental health perspectives 20110101

• Spinal cord injury causes sustained disruption of the blood-testis barrier in the rat.

  PloS one 20110101

• Ashwagandha leaf derived withanone protects normal human cells against the toxicity of methoxyacetic acid, a major industrial metabolite.

  PloS one 20110101

• Exposure to phthalates among premenstrual girls from rural and urban Gharbiah, Egypt: a pilot exposure assessment study.

  Environmental health : a global access science source 20110101

• Aromatase activity and bone loss in men.

  Journal of osteoporosis 20110101

• Do Thyroid Disrupting Chemicals Influence Foetal Development during Pregnancy?

  Journal of thyroid research 20110101

• In vitro acute exposure to DEHP affects oocyte meiotic maturation, energy and oxidative stress parameters in a large animal model.

  PloS one 20110101

• Mono-(2-ethylhexyl) phthalate directly alters the expression of Leydig cell genes and CYP17 lyase activity in cultured rat fetal testis.

  PloS one 20110101

• Chemical exposure as etiology in developmental origin of adult onset human cancer.

  Frontiers in pharmacology 20110101

• The endocrine disruptor mono-(2-ethylhexyl) phthalate affects the differentiation of human liposarcoma cells (SW 872).

  PloS one 20110101

• Gender-Specific Adverse Effects of Mono-Ethylhexyl Phthalate on Steroidogenesis in Immature Granulosa Cells and Rat Leydig cell Progenitors in vitro.

  Frontiers in endocrinology 20110101

• Variability over 1 week in the urinary concentrations of metabolites of diethyl phthalate and di(2-ethylhexyl) phthalate among eight adults: an observational study.

  Environmental health perspectives 20101201

• Evaluating the effects of immunotoxicants using carbon fiber microelectrode amperometry.

  Analytical and bioanalytical chemistry 20101201

• Deregulation of the Sod1 and Nd1 genes in mouse fetal oocytes exposed to mono-(2-ethylhexyl) phthalate (MEHP).

  Reproductive toxicology (Elmsford, N.Y.) 20101101

• Some flame retardants and the antimicrobials triclosan and triclocarban enhance the androgenic activity in vitro.

  Chemosphere 20101101

• Research recommendations for selected IARC-classified agents.

  Environmental health perspectives 20101001

• Prenatal exposure to phthalate esters and PAHs and birth outcomes.

  Environment international 20101001

• Childhood exposure to phthalates: associations with thyroid function, insulin-like growth factor I, and growth.

  Environmental health perspectives 20101001

• Evaluation of cytotoxicity and oxidative DNA damaging effects of di(2-ethylhexyl)-phthalate (DEHP) and mono(2-ethylhexyl)-phthalate (MEHP) on MA-10 Leydig cells and protection by selenium.

  Toxicology and applied pharmacology 20101001

• Production of phthalate esters by nuisance freshwater algae and cyanobacteria.

  The Science of the total environment 20101001

• Correlations between phthalate metabolites in urine, serum, and seminal plasma from young Danish men determined by isotope dilution liquid chromatography tandem mass spectrometry.

  Journal of analytical toxicology 20100901

• Protective effect of selenium supplementation on the genotoxicity of di(2-ethylhexyl)phthalate and mono(2-ethylhexyl)phthalate treatment in LNCaP cells.

  Free radical biology & medicine 20100815

• Effect of phthalate esters on the secretion of prostaglandins (F2alpha and E2) and oxytocin in cultured bovine ovarian and endometrial cells.

  Domestic animal endocrinology 20100801

• Inflammatory effects of phthalates in neonatal neutrophils.

  Pediatric research 20100801

• It's the plastic!: commentary on the article by Vetrano et al. on page 134.

  Pediatric research 20100801

• Relationship between environmental phthalate exposure and the intelligence of school-age children.

  Environmental health perspectives 20100701

• Investigation of relationships between urinary biomarkers of phytoestrogens, phthalates, and phenols and pubertal stages in girls.

  Environmental health perspectives 20100701

• Lung damage in mice after inhalation of nanofilm spray products: the role of perfluorination and free hydroxyl groups.

  Toxicological sciences : an official journal of the Society of Toxicology 20100701

• Dietary intake is associated with phthalate body burden in a nationally representative sample.

  Environmental health perspectives 20100701

• Molecular mechanisms mediating the effect of mono-(2-ethylhexyl) phthalate on hormone-stimulated steroidogenesis in MA-10 mouse tumor Leydig cells.

  Endocrinology 20100701

• Determination of five phthalate monoesters in human urine using gas chromatography-mass spectrometry.

  Bulletin of environmental contamination and toxicology 20100701

• Assessment of di (2-ethylhexyl) phthalate exposure by urinary metabolites as a function of sampling time.

  Journal of preventive medicine and public health = Yebang Uihakhoe chi 20100701

• Association of exposure to phthalates with endometriosis and uterine leiomyomata: findings from NHANES, 1999-2004.

  Environmental health perspectives 20100601

• Effect of a Large Dose of Di (2-ethylhexyl) phthalate (DEHP) on Hepatic Peroxisome in Cynomolgus Monkeys (Macaca Fascicularis).

  Journal of toxicologic pathology 20100601

• [Effect of DEHP and its metabolite MEHP on in vitro rat follicular development].

  Wei sheng yan jiu = Journal of hygiene research 20100501

• Prenatal phthalate exposure and reduced masculine play in boys.

  International journal of andrology 20100401

• FasL gene-deficient mice display a limited disruption in spermatogenesis and inhibition of mono-(2-ethylhexyl) phthalate-induced germ cell apoptosis.

  Toxicological sciences : an official journal of the Society of Toxicology 20100401

• Prenatal phthalate exposure is associated with childhood behavior and executive functioning.

  Environmental health perspectives 20100401

• Association of endocrine disruptors and obesity: perspectives from epidemiological studies.

  International journal of andrology 20100401

• Mixture effects of endocrine disrupting compounds in vitro.

  International journal of andrology 20100401

• Exposure to phthalates and breast cancer risk in northern Mexico.

  Environmental health perspectives 20100401

• Mono-(2-ethylhexyl) phthalate-induced disruption of junctional complexes in the seminiferous epithelium of the rodent testis is mediated by MMP2.

  Biology of reproduction 20100301

• Peroxisome proliferator-activated receptor-gamma mediates bisphenol A inhibition of FSH-stimulated IGF-1, aromatase, and estradiol in human granulosa cells.

  Environmental health perspectives 20100301

• Mono(2-ethylhexyl) phthalate induces both pro- and anti-inflammatory responses in rat alveolar macrophages through crosstalk between p38, the lipoxygenase pathway and PPARalpha.

  Inhalation toxicology 20100201

• Transcriptional biomarkers of steroidogenesis and trophoblast differentiation in the placenta in relation to prenatal phthalate exposure.

  Environmental health perspectives 20100201

• The pollutant diethylhexyl phthalate regulates hepatic energy metabolism via species-specific PPARalpha-dependent mechanisms.

  Environmental health perspectives 20100201

• To each his own: DEHP yields species-specific metabolic phenotypes.

  Environmental health perspectives 20100201

• Di-(2-ethylhexyl) phthalate and mono-(2-ethylhexyl) phthalate inhibit growth and reduce estradiol levels of antral follicles in vitro.

  Toxicology and applied pharmacology 20100115

• Structure-dependent inhibition of human and rat 11beta-hydroxysteroid dehydrogenase 2 activities by phthalates.

  Chemico-biological interactions 20100105

• Urinary di-(2-ethylhexyl)phthalate metabolites in athletes as screening measure for illicit blood doping: a comparison study with patients receiving blood transfusion.

  Transfusion 20100101

• Plasma phthalate levels in pubertal gynecomastia.

  Pediatrics 20100101

• Estrogenic in vitro assay on mouse embryonic Leydig cells.

  The International journal of developmental biology 20100101

• Sub-chronic lung inflammation after airway exposures to Bacillus thuringiensis biopesticides in mice.

  BMC microbiology 20100101

• Endocrine disruptors and Leydig cell function.

  Journal of biomedicine & biotechnology 20100101

• Antigenotoxic effect of Chamomilla recutita (L.) Rauschert essential oil in mouse spermatogonial cells, and determination of its antioxidant capacity in vitro.

  International journal of molecular sciences 20100101

• Variability of phthalate monoester levels in daily first-morning urine from adult women: a pilot study.

  Reviews on environmental health 20100101

• Urinary phthalate monoesters and endometriosis in infertile Japanese women.

  The Science of the total environment 20091215

• Mono-(2-ethylhexyl) phthalate induces NR4A subfamily and GIOT-1 gene expression, and suppresses CYP19 expression in human granulosa-like tumor cell line KGN.

  Toxicology letters 20091215

• Phthalates exposure and attention-deficit/hyperactivity disorder in school-age children.

  Biological psychiatry 20091115

• Mono-(2-ethylhexyl) phthalate (MEHP) regulates glucocorticoid metabolism through 11beta-hydroxysteroid dehydrogenase 2 in murine gonadotrope cells.

  Biochemical and biophysical research communications 20091113

• A reexamination of the PPAR-alpha activation mode of action as a basis for assessing human cancer risks of environmental contaminants.

  Environmental health perspectives 20091101

• Differential cytotoxic effects of mono-(2-ethylhexyl) phthalate on blastomere-derived embryonic stem cells and differentiating neurons.

  Toxicology 20091029

• Phthalates impair germ cell number in the mouse fetal testis by an androgen- and estrogen-independent mechanism.

  Toxicological sciences : an official journal of the Society of Toxicology 20091001

• What additional factors beyond state-of-the-art analytical methods are needed for optimal generation and interpretation of biomonitoring data?

  Environmental health perspectives 20091001

• Urinary phthalate metabolites in relation to preterm birth in Mexico city.

  Environmental health perspectives 20091001

• Improving in vitro Sertoli cell/gonocyte co-culture model for assessing male reproductive toxicity: Lessons learned from comparisons of cytotoxicity versus genomic responses to phthalates.

  Toxicology and applied pharmacology 20090915

• Effect of fetal or neonatal exposure to monobutyl phthalate (MBP) on testicular development and function in the marmoset.

  Human reproduction (Oxford, England) 20090901

• Effect of mono-(2-ethylhexyl) phthalate on steroid production of human granulosa cells.

  Toxicology and applied pharmacology 20090815

• Effect of gamma-ray irradiation on degradation of di(2-ethylhexyl)phthalate in polyvinyl chloride sheet.

  International journal of pharmaceutics 20090706

• Mono-(2-ethylhexyl) phthalate targets glycogen debranching enzyme and affects glycogen metabolism in rat testis.

  Toxicological sciences : an official journal of the Society of Toxicology 20090501

• Maternal urinary metabolites of Di-(2-Ethylhexyl) phthalate in relation to the timing of labor in a US multicenter pregnancy cohort study.

  American journal of epidemiology 20090415

• Time- and dose-related effects of di-(2-ethylhexyl) phthalate and its main metabolites on the function of the rat fetal testis in vitro.

  Environmental health perspectives 20090401

• Exposure to bisphenol A and other phenols in neonatal intensive care unit premature infants.

  Environmental health perspectives 20090401

• Steroidogenesis-disrupting compounds can be effectively studied for major fertility-related endpoints using in vitro cultured mouse follicles.

  Toxicology letters 20090328

• TNF alpha-mediated disruption of spermatogenesis in response to Sertoli cell injury in rodents is partially regulated by MMP2.

  Biology of reproduction 20090301

• Lactational exposure to phthalates in Southern Italy.

  Environment international 20090201

• Phthalate exposure among pregnant women in Jerusalem, Israel: results of a pilot study.

  Environment international 20090201

• Medications as a potential source of exposure to phthalates in the U.S. population.

  Environmental health perspectives 20090201

• A concentration addition model for the activation of the constitutive androstane receptor by xenobiotic mixtures.

  Toxicological sciences : an official journal of the Society of Toxicology 20090101

• Urinary metabolites of di(2-ethylhexyl) phthalate are associated with decreased steroid hormone levels in adult men.

  Journal of andrology 20090101

• Phthalates impair germ cell development in the human fetal testis in vitro without change in testosterone production.

  Environmental health perspectives 20090101

• Concentrations of phthalate metabolites in milk, urine, saliva, and Serum of lactating North Carolina women.

  Environmental health perspectives 20090101

• Phthalate exposure in girls during early puberty.

  Journal of pediatric endocrinology & metabolism : JPEM 20090101

• Placental biomarkers of phthalate effects on mRNA transcription: application in epidemiologic research.

  Environmental health : a global access science source 20090101

• p,p'-DDE induces apoptosis of rat Sertoli cells via a FasL-dependent pathway.

  Journal of biomedicine & biotechnology 20090101

• Di-(2 ethylhexyl) phthalate and flutamide alter gene expression in the testis of immature male rats.

  Reproductive biology and endocrinology : RB&E 20090101

• Desensitization of ovalbumin-sensitized mice by repeated co-administrations of di-(2-ethylhexyl) phthalate and ovalbumin.

  BMC research notes 20090101

• Risk reduction of adverse effects due to di-(2-ethylhexyl) phthalate (DEHP) by utilizing microbial degradation.

  Journal of toxicology and environmental health. Part A 20090101

• Comparative toxicological evaluation of phthalate diesters and metabolites in Sprague-Dawley male rats for risk assessment.

  Journal of toxicology and environmental health. Part A 20090101

• An exposure assessment of di-(2-ethylhexyl) phthalate (DEHP) and di-n-butyl phthalate (DBP) in human semen.

  Journal of toxicology and environmental health. Part A 20090101

• Phthalate esters used as plasticizers in packed red blood cell storage bags may lead to progressive toxin exposure and the release of pro-inflammatory cytokines.

  Oxidative medicine and cellular longevity 20090101

• Cross-talk between the Akt and NF-kappaB signaling pathways inhibits MEHP-induced germ cell apoptosis.

  Toxicological sciences : an official journal of the Society of Toxicology 20081201

• Maternal and infant urinary phthalate metabolite concentrations: are they related?

  Environmental research 20081101

• Use of the rat postimplantation embryo culture to assess the embryotoxic potency within a chemical category and to identify toxic metabolites.

  Toxicology in vitro : an international journal published in association with BIBRA 20081001

• Antagonistic effects of testosterone and the endocrine disruptor mono-(2-ethylhexyl) phthalate on INSL3 transcription in Leydig cells.

  Endocrinology 20080901

• Effects of maternal exposure to di-(2-ethylhexyl) phthalate during fetal and/or neonatal periods on atopic dermatitis in male offspring.

  Environmental health perspectives 20080901

• Biological monitoring of occupational exposure to di(2-ethylhexyl) phthalate: survey of workers exposed to plastisols.

  International archives of occupational and environmental health 20080801

• Inhibitory effects of mono-ethylhexyl phthalate on steroidogenesis in immature and adult rat Leydig cells in vitro.

  Reproductive toxicology (Elmsford, N.Y.) 20080801

• An endogenous prostaglandin enhances environmental phthalate-induced apoptosis in bone marrow B cells: activation of distinct but overlapping pathways.

  Journal of immunology (Baltimore, Md. : 1950) 20080801

• Prenatal phenol and phthalate exposures and birth outcomes.

  Environmental health perspectives 20080801

• Validation and application of an HPLC method for determination of di (2-ethylhexyl) phthalate and mono (2-ethylhexyl) phthalate in liver samples.

  Journal of chromatographic science 20080801

• The role of exposure to phthalates from polyvinyl chloride products in the development of asthma and allergies: a systematic review and meta-analysis.

  Environmental health perspectives 20080701

• Disruption effects of monophthalate exposures on inter-Sertoli tight junction in a two-compartment culture model.

  Environmental toxicology 20080601

• Phthalate induction of CYP3A4 is dependent on glucocorticoid regulation of PXR expression.

  Toxicological sciences : an official journal of the Society of Toxicology 20080601

• Mono-(2-ethylhexyl) phthalate stimulates basal steroidogenesis by a cAMP-independent mechanism in mouse gonadal cells of both sexes.

  Reproduction (Cambridge, England) 20080501

• Urinary phthalate metabolites and semen quality: a review of a potential biomarker of susceptibility.

  International journal of andrology 20080401

• Characterization of phthalate exposure among pregnant women assessed by repeat air and urine samples.

  Environmental health perspectives 20080401

• Simulated neonatal exposure to DEHP and MEHP from PVC enteral nutrition products.

  International journal of pharmaceutics 20080320

• Phthalate diesters and their metabolites in human breast milk, blood or serum, and urine as biomarkers of exposure in vulnerable populations.

  Environmental health perspectives 20080301

• [Levels of environmental endocrine disruptors in umbilical cord blood and maternal blood of low-birth-weight infants].

  Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] 20080301

• Mono-(2-ethylhexyl) phthalate increases spermatocyte mitochondrial peroxiredoxin 3 and cyclooxygenase 2.

  Journal of andrology 20080101

• The association between phthalates in dust and allergic diseases among Bulgarian children.

  Environmental health perspectives 20080101

• Peroxisome proliferator-activated receptors as mediators of phthalate-induced effects in the male and female reproductive tract: epidemiological and experimental evidence.

  PPAR research 20080101

• PPAR Gamma: Coordinating Metabolic and Immune Contributions to Female Fertility.

  PPAR research 20080101

• PPARs and Female Reproduction: Evidence from Genetically Manipulated Mice.

  PPAR research 20080101

• Association of urinary phthalate metabolite concentrations with body mass index and waist circumference: a cross-sectional study of NHANES data, 1999-2002.

  Environmental health : a global access science source 20080101

• Mitochondria, PPARs, and Cancer: Is Receptor-Independent Action of PPAR Agonists a Key?

  PPAR research 20080101

• PPARalpha- and DEHP-Induced Cancers.

  PPAR research 20080101

• Structure-activity relationship of immunostimulatory effects of phthalates.

  BMC immunology 20080101

• Effect of mono-(2-ethylhexyl) phthalate (MEHP) on resumption of meiosis, in vitro maturation and embryo development of immature mouse oocytes.

  BioFactors (Oxford, England) 20080101

• HPLC with diode-array detection for the simultaneous determination of di(2-ethylhexyl)phthalate and mono(2-ethylhexyl)phthalate in seminal plasma.

  Biomedical chromatography : BMC 20071101

• Associations between urinary phthalate monoesters and thyroid hormones in pregnant women.

  Human reproduction (Oxford, England) 20071001

• Developmental toxicity and uterotrophic studies with di-2-ethylhexyl terephthalate.

  Birth defects research. Part B, Developmental and reproductive toxicology 20071001

• Preventive effect of D-psicose, one of rare ketohexoses, on di-(2-ethylhexyl) phthalate (DEHP)-induced testicular injury in rat.

  Toxicology letters 20070910

• Cumulative effects of dibutyl phthalate and diethylhexyl phthalate on male rat reproductive tract development: altered fetal steroid hormones and genes.

  Toxicological sciences : an official journal of the Society of Toxicology 20070901

• Mono-(2-ethylhexyl) phthalate (MEHP) induces nuclear receptor 4A subfamily in NCI-H295R cells: a possible mechanism of aromatase suppression by MEHP.

  Molecular and cellular endocrinology 20070815

• Phagocytosis plays an important role in clearing dead cells caused by mono(2-ethylhexyl) phthalate administration.

  Tissue & cell 20070801

• Dose-dependent effects of sertoli cell toxicants 2,5-hexanedione, carbendazim, and mono-(2-ethylhexyl) phthalate in adult rat testis.

  Toxicologic pathology 20070801

• An L-tyrosine derivative and PPARgamma agonist, GW7845, activates a multifaceted caspase cascade in bone marrow B cells.

  Toxicological sciences : an official journal of the Society of Toxicology 20070701

• Di(2-ethylhexyl) phthalate metabolites may alter thyroid hormone levels in men.

  Environmental health perspectives 20070701

• The endocrine disruptor monoethyl-hexyl-phthalate is a selective peroxisome proliferator-activated receptor gamma modulator that promotes adipogenesis.

  The Journal of biological chemistry 20070629

• Concentrations of urinary phthalate metabolites are associated with increased waist circumference and insulin resistance in adult U.S. males.

  Environmental health perspectives 20070601

• Adjuvant effects of inhaled mono-2-ethylhexyl phthalate in BALB/cJ mice.

  Toxicology 20070322

• Short-term effects of di-(2-ethylhexyl) phthalate on testes, liver, kidneys and pancreas in mice.

  Asian journal of andrology 20070301

• DNA damage in human sperm is related to urinary levels of phthalate monoester and oxidative metabolites.

  Human reproduction (Oxford, England) 20070301

• Toxicokinetic relationship between di(2-ethylhexyl) phthalate (DEHP) and mono(2-ethylhexyl) phthalate in rats.

  Journal of toxicology and environmental health. Part A 20070301

• Transcriptional regulation of FasL expression and participation of sTNF-alpha in response to sertoli cell injury.

  The Journal of biological chemistry 20070223

• Studies of uptake, elimination, and late effects in Atlantic salmon (Salmo salar) dietary exposed to Di-2-ethylhexyl phthalate (DEHP) during early life.

  Archives of environmental contamination and toxicology 20070201

• Effect of a hypolipidemic drug, Di (2-ethylhexyl) phthalate, on mRNA-expression associated fatty acid and acetate metabolism in rat tissues.

  Bioscience, biotechnology, and biochemistry 20070201

• An ultrastructural study on the effects of mono(2-ethylhexyl) phthalate on mice testes: cell death and sloughing of spermatogenic cells.

  Okajimas folia anatomica Japonica 20070201

• Peroxisome proliferator-activated receptor alpha protects against glomerulonephritis induced by long-term exposure to the plasticizer di-(2-ethylhexyl)phthalate.

  Journal of the American Society of Nephrology : JASN 20070101

• Occurrence and daily variation of phthalate metabolites in the urine of an adult population.

  International journal of hygiene and environmental health 20070101

• Daily intake of di(2-ethylhexyl)phthalate (DEHP) by German children -- A comparison of two estimation models based on urinary DEHP metabolite levels.

  International journal of hygiene and environmental health 20070101

• Stimulation of the pituitary-adrenal axis and of adrenocortical steroidogenesis ex vivo by administration of di-2-ethylhexyl phthalate to prepubertal male rats.

  The Journal of endocrinology 20070101

• Pilot study of urinary biomarkers of phytoestrogens, phthalates, and phenols in girls.

  Environmental health perspectives 20070101

• Transplacental transfer of monomethyl phthalate and mono(2-ethylhexyl) phthalate in a human placenta perfusion system.

  International journal of toxicology 20070101

• Disappearance of vimentin in Sertoli cells: a mono(2-ethylhexyl) phthalate effect.

  International journal of toxicology 20070101

• Effect of in utero exposure to di-(2-ethylhexyl)phthalate: distribution in the rat fetus and testosterone production by rat fetal testis in culture.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20061201

• Testicular germ cell sensitivity to TRAIL-induced apoptosis is dependent upon p53 expression and is synergistically enhanced by DR5 agonistic antibody treatment.

  Apoptosis : an international journal on programmed cell death 20061201

• Expression of stress inducible protein 1 (Stip1) in the mouse testis.

  Molecular reproduction and development 20061101

• Decreased serum free testosterone in workers exposed to high levels of di-n-butyl phthalate (DBP) and di-2-ethylhexyl phthalate (DEHP): a cross-sectional study in China.

  Environmental health perspectives 20061101

• Integrating biomonitoring exposure data into the risk assessment process: phthalates [diethyl phthalate and di(2-ethylhexyl) phthalate] as a case study.

  Environmental health perspectives 20061101

• European Academy of Paediatrics, Barcelona, Spain, October 7-10, 2006. Abstracts.

  European journal of pediatrics 20061101

• Testicular gene expression profiling following prepubertal rat mono-(2-ethylhexyl) phthalate exposure suggests a common initial genetic response at fetal and prepubertal ages.

  Toxicological sciences : an official journal of the Society of Toxicology 20061001

• Toxicity of di(2-ethylhexyl)phthalate (DEHP) and di(2-ethylhexyl)adipate (DEHA) under conditions of renal dysfunction induced with folic acid in rats: enhancement of male reproductive toxicity of DEHP is associated with an increase of the mono-derivative.

  Reproductive toxicology (Elmsford, N.Y.) 20061001

• Exposure to phthalates in neonatal intensive care unit infants: urinary concentrations of monoesters and oxidative metabolites.

  Environmental health perspectives 20060901

• Oxidative metabolites of diisononyl phthalate as biomarkers for human exposure assessment.

  Environmental health perspectives 20060801

• Mono(2-ethylhexyl)phthalate and mono-n-butyl phthalate activation of peroxisome proliferator activated-receptors alpha and gamma in breast.

  Toxicology letters 20060601

• Estimated daily phthalate exposures in a population of mothers of male infants exhibiting reduced anogenital distance.

  Environmental health perspectives 20060601

• Effect of sterilization process on the formation of mono(2-ethylhexyl)phthalate from di(2-ethylhexyl)phthalate.

  Journal of pharmaceutical and biomedical analysis 20060503

• Effects of di-(2-ethylhexyl)-phthalate and its metabolites on the lipid profiling in rat HRP-1 trophoblast cells.

  Archives of toxicology 20060501

• Mono-(2-ethylhexyl) phthalate rapidly increases celsr2 protein phosphorylation in HeLa cells via protein kinase C and casein kinase 1.

  Toxicological sciences : an official journal of the Society of Toxicology 20060501

• [Estimation of intake level of di (2-ethyhexyl) phthalate (DEHP) in Japanese pregnant women based on measurement of concentrations of three urinary metabolites].

  Nihon eiseigaku zasshi. Japanese journal of hygiene 20060501

• [Determination of four kinds of environmental endocrine disruptors in blood serum of precocious puberty patients by high performance liquid chromatography].

  Wei sheng yan jiu = Journal of hygiene research 20060501

• Influence of TRP53 status on FAS membrane localization, CFLAR (c-FLIP) ubiquitinylation, and sensitivity of GC-2spd (ts) cells to undergo FAS-mediated apoptosis.

  Biology of reproduction 20060301

• Urinary oxidative metabolites of di(2-ethylhexyl) phthalate in humans.

  Toxicology 20060215

• Human breast milk contamination with phthalates and alterations of endogenous reproductive hormones in infants three months of age.

  Environmental health perspectives 20060201

• Low serum concentrations of di-(2-ethylhexyl)phthalate in women with uterine fibromatosis.

  Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20060201

• Urinary and amniotic fluid levels of phthalate monoesters in rats after the oral administration of di(2-ethylhexyl) phthalate and di-n-butyl phthalate.

  Toxicology 20060105

• Measurement of eight urinary metabolites of di(2-ethylhexyl) phthalate as biomarkers for human exposure assessment.

  Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20060101

• Kinetic analysis of the transformation of phthalate esters in a series of stoichiometric reactions in anaerobic wastes.

  Applied microbiology and biotechnology 20051201

• Detection of phthalate metabolites in human saliva.

  Archives of toxicology 20051101

• Personal care product use predicts urinary concentrations of some phthalate monoesters.

  Environmental health perspectives 20051101

• High-throughput determination of mono- and di(2-ethylhexyl)phthalate migration from PVC tubing to drugs using liquid chromatography-tandem mass spectrometry.

  Journal of pharmaceutical and biomedical analysis 20051004

• PVC-plasticizer DEHP in medical products: do thin coatings really reduce DEHP leaching into blood?

  Perfusion 20051001

• Use of di(2-ethylhexyl) phthalate-containing medical products and urinary levels of mono(2-ethylhexyl) phthalate in neonatal intensive care unit infants.

  Environmental health perspectives 20050901

• Human monitoring of phthalates and risk assessment.

  Journal of toxicology and environmental health. Part A 20050827

• CAR and PXR: xenosensors of endocrine disrupters?

  Chemico-biological interactions 20050815

• Evaluation and analysis of exposure levels of di(2-ethylhexyl) phthalate from blood bags.

  Clinica chimica acta; international journal of clinical chemistry 20050801

• Decrease in anogenital distance among male infants with prenatal phthalate exposure.

  Environmental health perspectives 20050801

• Mono-(2-ethylhexyl) phthalate (MEHP) induces testicular alterations in male guinea pigs at prepubertal stage.

  Tissue & cell 20050601

• Determination of phthalate monoesters in human milk, consumer milk, and infant formula by tandem mass spectrometry (LC-MS-MS).

  Analytical and bioanalytical chemistry 20050601

• [Material monograph on di(2-ethylhexyl)phthalat (DEHP)--reference values for 5oxo-MEHP und 5OH-MEHP in urine].

  Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz 20050601

• Effects of di-(2-ethylhexyl)-phthalate (DEHP) and its metabolites on fatty acid homeostasis regulating proteins in rat placental HRP-1 trophoblast cells.

  Toxicological sciences : an official journal of the Society of Toxicology 20050401

• Alkyl phenols and diethylhexyl phthalate in tissues of sheep grazing pastures fertilized with sewage sludge or inorganic fertilizer.

  Environmental health perspectives 20050401

• Evidence of interaction between polychlorinated biphenyls and phthalates in relation to human sperm motility.

  Environmental health perspectives 20050401

• [Effects of mono(2-ethylhexyl) phthalate on testosterone biosynthesis in leydig cells cultured from the rat testis].

  Zhonghua nan ke xue = National journal of andrology 20050401

• Biodegradation of an endocrine-disrupting chemical, di-2-ethylhexyl phthalate, by Bacillus subtilis No. 66.

  Applied microbiology and biotechnology 20050301

• Differential effects of phthalates on the testis and the liver.

  Biology of reproduction 20050301

• Evaluation of anti-androgenic activity of di-(2-ethylhexyl)phthalate.

  Toxicology 20050301

• Species differences in the metabolism of di(2-ethylhexyl) phthalate (DEHP) in several organs of mice, rats, and marmosets.

  Archives of toxicology 20050301

• NF-kappaB is activated in the rat testis following exposure to mono-(2-ethylhexyl) phthalate.

  Biology of reproduction 20050201

• Role of PPARalpha in mediating the effects of phthalates and metabolites in the liver.

  Toxicology 20050201

• The p53 protein influences the sensitivity of testicular germ cells to mono-(2-ethylhexyl) phthalate-induced apoptosis by increasing the membrane levels of Fas and DR5 and decreasing the intracellular amount of c-FLIP.

  Biology of reproduction 20050101

• Evaluation of the effect of governmental control of human exposure to two phthalates in Japan using a urinary biomarker approach.

  International journal of hygiene and environmental health 20050101

• Microbial production and vaporization of mono-(2-ethylhexyl) phthalate from di-(2-ethylhexyl) phthalate by microorganisms inside houses.

  Archives of environmental & occupational health 20050101

• Temporal variability of urinary phthalate metabolite levels in men of reproductive age.

  Environmental health perspectives 20041201

• Evidence for a new human CYP1A1 regulation pathway involving PPAR-alpha and 2 PPRE sites.

  Gastroenterology 20041101

• Effects of mono-2-ethylhexyl phthalate on the respiratory tract in BALB/c mice.

  Human & experimental toxicology 20041101

• Evaluation of the direct toxicity of trioctyltrimellitate (TOTM), di(2-ethylhexyl) phthalate (DEHP) and their hydrolysis products on isolated rat hepatocytes.

  The International journal of artificial organs 20041101

• Phthalate esters enhance quinolinate production by inhibiting alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase (ACMSD), a key enzyme of the tryptophan pathway.

  Toxicological sciences : an official journal of the Society of Toxicology 20041001

• 4-Heptanone is a metabolite of the plasticizer di(2-ethylhexyl) phthalate (DEHP) in haemodialysis patients.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20041001

• Environmental phthalate monoesters activate pregnane X receptor-mediated transcription.

  Toxicology and applied pharmacology 20040915

• Environmental and endogenous peroxisome proliferator-activated receptor gamma agonists induce bone marrow B cell growth arrest and apoptosis: interactions between mono(2-ethylhexyl)phthalate, 9-cis-retinoic acid, and 15-deoxy-Delta12,14-prostaglandin J2.

  Journal of immunology (Baltimore, Md. : 1950) 20040901

• Follow-up study of adolescents exposed to di(2-ethylhexyl) phthalate (DEHP) as neonates on extracorporeal membrane oxygenation (ECMO) support.

  Environmental health perspectives 20040901

• An ultrastructural study on cytotoxic effects of mono(2-ethylhexyl) phthalate (MEHP) on testes in Shiba goat in vitro.

  Journal of veterinary science 20040901

• The use of mini-organ cultures of human upper aerodigestive tract epithelia in ecogenotoxicology.

  Mutation research 20040711

• Kinetics of orally administered di(2-ethylhexyl) phthalate and its metabolite, mono(2-ethylhexyl) phthalate, in male pigs.

  Archives of toxicology 20040701

• Phthalate exposure and early thelarche.

  Environmental health perspectives 20040701

• Monophthalates promote IL-6 and IL-8 production in the human epithelial cell line A549.

  Toxicology in vitro : an international journal published in association with BIBRA 20040601

• Determination of di(2-ethylhexyl)phthalate and mono(2-ethylhexyl)phthalate in human serum using liquid chromatography-tandem mass spectrometry.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040525

• Medications as a source of human exposure to phthalates.

  Environmental health perspectives 20040501

• Exposure to di-(2-ethylhexyl) phthalate among premature neonates in a neonatal intensive care unit.

  Pediatrics 20040501

• Sensitive biomonitoring of phthalate metabolites in human urine using packed capillary column switching liquid chromatography coupled to electrospray ionization ion-trap mass spectrometry.

  Analytical and bioanalytical chemistry 20040401

• Phthalate exposure and pulmonary function.

  Environmental health perspectives 20040401

• Di(2-ethylhexyl)phthalate (DEHP) metabolites in human urine and serum after a single oral dose of deuterium-labelled DEHP.

  Archives of toxicology 20040301

• Blood burden of di(2-ethylhexyl) phthalate and its primary metabolite mono(2-ethylhexyl) phthalate in pregnant and nonpregnant rats and marmosets.

  Toxicology and applied pharmacology 20040301

• Mono(2-ethyl-5-hydroxyhexyl) phthalate and mono-(2-ethyl-5-oxohexyl) phthalate as biomarkers for human exposure assessment to di-(2-ethylhexyl) phthalate.

  Environmental health perspectives 20040301

• Urinary levels of seven phthalate metabolites in the U.S. population from the National Health and Nutrition Examination Survey (NHANES) 1999-2000.

  Environmental health perspectives 20040301

• Effects of mono(2-ethylhexyl) phthalate (MEHP) on testes in rats in vitro.

  Okajimas folia anatomica Japonica 20040301

• Mono-(2-ethylhexyl) phthalate (MEHP) induces spermatogenic cell apoptosis in guinea pig testes at prepubertal stage in vitro.

  International journal of toxicology 20040101

• Effects of mono-(2-ethylhexyl) phthalate on fetal and neonatal rat testis organ cultures.

  Biology of reproduction 20031201

• In utero exposure to di-(2-ethylhexyl)phthalate and duration of human pregnancy.

  Environmental health perspectives 20031101

• Induction of apoptosis by mono(2-ethylhexyl)phthalate (MEHP) in U937 cells.

  Toxicology letters 20031015

• Glucuronidation patterns of common urinary and serum monoester phthalate metabolites.

  Archives of toxicology 20031001

• Activation of PPARalpha and PPARgamma by environmental phthalate monoesters.

  Toxicological sciences : an official journal of the Society of Toxicology 20030801

• The effects of mono-2-ethylhexyl phathalate, adriamycin and N-ethyl-N-nitrosourea on stage-specific apoptosis and DNA synthesis in the mouse spermatogenesis.

  Toxicology letters 20030720

• High plasma concentrations of di-(2-ethylhexyl)-phthalate in women with endometriosis.

  Human reproduction (Oxford, England) 20030701

• Assessing human exposure to phthalates using monoesters and their oxidized metabolites as biomarkers.

  Environmental health perspectives 20030701

• Estrogenic activity of tissue conditioners in vitro.

  Dental materials : official publication of the Academy of Dental Materials 20030601

• Determination of three phthalate metabolites in human urine using on-line solid-phase extraction-liquid chromatography-tandem mass spectrometry.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030525

• Dual activation of PPARalpha and PPARgamma by mono-(2-ethylhexyl) phthalate in rat ovarian granulosa cells.

  Molecular and cellular endocrinology 20030328

• Fas- or FasL-deficient mice display an increased sensitivity to nitrobenzene-induced testicular germ cell apoptosis.

  Toxicology letters 20030320

• Investigation of the adjuvant and immuno-suppressive effects of benzyl butyl phthalate, phthalic acid and benzyl alcohol in a murine injection model.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20030301

• Removal of bis(2-ethylhexyl) phthalate at a sewage treatment plant.

  Water research 20030301

• Mechanisms of phthalate ester toxicity in the female reproductive system.

  Environmental health perspectives 20030201

• Column-switching high-performance liquid chromatography electrospray mass spectrometry coupled with on-line of extraction for the determination of mono- and di-(2-ethylhexyl) phthalate in blood samples.

  Analytical and bioanalytical chemistry 20030201

• Exposure to Di(2-ethylhexyl)phthalate in humans during pregnancy. A preliminary report.

  Biology of the neonate 20030101

• Effect of mono-(2-ethylhexyl) phthalate on bovine oocyte maturation in vitro.

  Reproductive toxicology (Elmsford, N.Y.) 20030101

• Transformation of phthalates in young landfill cells.

  Waste management (New York, N.Y.) 20030101

• Induction of propranolol metabolism in isolated rats hepatocytes treated by di(2-ethylhexyl) phthalate (DEHP) and mono(2-ethylhexyl) phthalate (MEHP).

  European journal of drug metabolism and pharmacokinetics 20030101

• Death receptor response in rodent testis after mono-(2-ethylhexyl) phthalate exposure.

  Toxicology and applied pharmacology 20021201

• Simultaneous determination of phthalate di- and monoesters in poly(vinylchloride) products and human saliva by gas chromatography-mass spectrometry.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20021115

• Defining the cellular and molecular mechanisms of toxicant action in the testis.

  Toxicology letters 20021005

• Reproducibility of urinary phthalate metabolites in first morning urine samples.

  Environmental health perspectives 20020501

• Comparative effects of phthalate monoesters on gap junctional intercellular communication and peroxisome proliferation in rodent and primate hepatocytes.

  Journal of toxicology and environmental health. Part A 20020426

• Phthalate esters detected in various water samples and biodegradation of the phthalates by microbes isolated from river water.

  Biological & pharmaceutical bulletin 20020201

• A comparative study of cytotoxic effects of N-ethyl-N-nitrosourea, adriamycin, and mono-(2-ethylhexyl)phthalate on mouse primordial germ cells.

  Cell biology and toxicology 20020101

• Di-(2-ethylhexyl) phthalate possesses an adjuvant effect in a subcutaneous injection model with BALB/c mice.

  Toxicology letters 20011215

• Adjuvant and immuno-suppressive effect of six monophthalates in a subcutaneous injection model with BALB/c mice.

  Toxicology 20011201

• Reversibility and persistence of di-2-ethylhexyl phthalate (DEHP)- and phenobarbital-induced hepatocellular changes in rodents.

  Toxicological sciences : an official journal of the Society of Toxicology 20011201

• [Simplified determination of di (2-ethylhexyl) phthalate (DEHP) and mono- (2-ethylhexyl) phthalate (MEHP) in blood and organs of the rat administered DEHP].

  Sangyo eiseigaku zasshi = Journal of occupational health 20010701

• The acute effects of mono(2-ethylhexyl)phthalate (MEHP) on testes of prepubertal Wistar rats.

  Toxicology letters 20010531

• Mono-(2-ethylhexyl) phthalate suppresses aromatase transcript levels and estradiol production in cultured rat granulosa cells.

  Toxicology and applied pharmacology 20010501

• No background concentrations of di(2-ethylhexyl) phthalate and mono(2-ethylhexyl) phthalate in blood of rats.

  Archives of toxicology 20010301

• Effect of mono-ethylhexyl phthalate on MA-10 Leydig tumor cells.

  Reproductive toxicology (Elmsford, N.Y.) 20010101

• trans-Activation of PPARalpha and PPARgamma by structurally diverse environmental chemicals.

  Toxicology and applied pharmacology 19991201

• Induction of cyclooxygenase-2 expression by peroxisome proliferators and non-tetradecanoylphorbol 12,13-myristate-type tumor promoters in immortalized mouse liver cells.

  The Journal of biological chemistry 19970207

• Growth regulation by peroxisome proliferators: opposing activities in early and late G1.

  Cancer research 19960715

• Effects of hepatic peroxisome proliferators and 12-O-tetradecanoyl phorbol-13-acetate on catalase and other enzyme activities of embryonic cells in vitro.

  Biochemical pharmacology 19900201

• Morphological transformation and catalase activity of Syrian hamster embryo cells treated with hepatic peroxisome proliferators, TPA and nickel sulphate.

  Cell biology and toxicology 19900101

• Peroxisome proliferation in primary cultures of rat hepatocytes.

  Toxicology and applied pharmacology 19830101