4415-82-1 | Cyclobutanemethanol

Packsize	Purity	Availability	Price	Discounted Price
1g	97%	in stock	$10.00	$7.00
5g	97%	in stock	$12.00	$9.00
25g	97%	in stock	$43.00	$30.00
500g	97%	in stock	$760.00	$532.00

Description

• Catalog Number: AB72303
• Chemical Name: Cyclobutanemethanol
• CAS Number: 4415-82-1
• Molecular Formula: C5H10O
• Molecular Weight: 86.1323
• MDL Number: MFCD00001330
• SMILES: OCC1CCC1

Computed Properties

• Complexity: 39.2
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 6
• Hydrogen Bond Acceptor Count: 1
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 1
• XLogP3: 0.8

Upstream Synthesis Route

Cyclobutylmethanol, also known as cyclobutanol, is a versatile compound that finds wide applicability in chemical synthesis processes. Due to its unique chemical structure, cyclobutylmethanol serves as a valuable building block in the creation of various organic compounds. In synthetic chemistry, it is commonly employed as a precursor in the preparation of complex molecules and pharmaceutical intermediates.The relatively small size of the cyclobutyl ring in cyclobutylmethanol allows for precise control over the stereochemistry of reactions, making it a favored choice for organic chemists seeking to achieve specific molecular configurations. Additionally, the presence of the alcohol functional group in cyclobutylmethanol enables its transformation into various functionalized derivatives through straightforward chemical reactions such as oxidation, esterification, and substitution.In organic synthesis, cyclobutylmethanol serves as a valuable tool for constructing cyclic structures, heterocycles, and natural product analogs. Its strategic incorporation into synthetic routes allows chemists to access diverse chemical space and tailor the properties of target compounds for specific applications in medicinal chemistry, material science, and agrochemicals. Furthermore, the reactivity and stability of cyclobutylmethanol make it a reliable reagent for forming carbon-carbon and carbon-heteroatom bonds with high regio- and stereoselectivity, facilitating the efficient synthesis of complex molecules with desired functionalities.

Literature

• Ring opening versus ring expansion in rearrangement of bicyclic cyclobutylcarbinyl radicals.

  The Journal of organic chemistry 20080201

• Entamoeba histolytica alcohol dehydrogenase 2 (EhADH2) as a target for anti-amoebic agents.

  The Journal of antimicrobial chemotherapy 20040701