4425-56-3 | 2,4-Dihydroxypyrimidine-5-carbonitrile

Packsize	Purity	Availability	Price	Discounted Price
100mg	98%	in stock	$8.00	$5.00
250mg	98%	in stock	$10.00	$7.00
1g	98%	in stock	$25.00	$17.00
5g	98%	in stock	$53.00	$38.00
10g	98%	in stock	$98.00	$69.00
25g	98%	in stock	$217.00	$152.00
100g	98%	in stock	$782.00	$547.00

Description

• Catalog Number: AD29316
• Chemical Name: 2,4-Dihydroxypyrimidine-5-carbonitrile
• CAS Number: 4425-56-3
• Molecular Formula: C5H3N3O2
• Molecular Weight: 137.0962
• MDL Number: MFCD00051958
• SMILES: N#Cc1c[nH]c(=O)[nH]c1=O

Computed Properties

• Complexity: 270
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 10
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 2
• XLogP3: -0.9

Literature

• [Ru(bpy)2(5-cyanouracil)2]2+ as a potential light-activated dual-action therapeutic agent.

  Inorganic chemistry 20111003

• Synthesis and antimicrobial evaluation of some 6-aryl-5-cyano-2-thiouracil derivatives.

  Acta pharmaceutica (Zagreb, Croatia) 20110601

• Metal-ion selectivity of chemically modified uracil pairs in DNA duplexes.

  Angewandte Chemie (International ed. in English) 20090101

• Metal ion binding of modified pyrimidine-base pairs in DNA duplexes.

  Nucleic acids symposium series (2004) 20090101

• A multi-component reaction to 5-cyanouracils: synthesis and mechanistic study.

  Bioorganic & medicinal chemistry 20060515

• Parallel synthesis of 5-cyano-6-aryl-2-thiouracil derivatives as inhibitors for hepatitis C viral NS5B RNA-dependent RNA polymerase.

  Bioorganic chemistry 20060201

• Design and synthesis of the tumor-activated prodrug of dihydropyrimidine dehydrogenase (DPD) inhibitor, RO0094889 for combination therapy with capecitabine.

  Bioorganic & medicinal chemistry letters 20030310