443-69-6 | 5-Fluoroindoline-2,3-dione

Packsize	Purity	Availability	Price	Discounted Price
100mg	98%	in stock	$6.00	$4.00
5g	98%	in stock	$7.00	$5.00
10g	98%	in stock	$10.00	$7.00
25g	98%	in stock	$19.00	$14.00
500g	98%	in stock	$276.00	$193.00

Description

• Catalog Number: AB45307
• Chemical Name: 5-Fluoroindoline-2,3-dione
• CAS Number: 443-69-6
• Molecular Formula: C8H4FNO2
• Molecular Weight: 165.1213
• MDL Number: MFCD00022795
• SMILES: Fc1ccc2c(c1)C(=O)C(=O)N2
• NSC Number: 39161

Computed Properties

• Complexity: 241
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 12
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 1
• XLogP3: 0.7

Literature

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  Acta crystallographica. Section E, Structure reports online 20120301

• (Z)-2-(5-Fluoro-2-oxoindolin-3-yl-idene)-N-phenyl-hydrazinecarbothio-amide.

  Acta crystallographica. Section E, Structure reports online 20120201

• Chemical synthesis, in vitro acetohydroxyacid synthase (AHAS) inhibition, herbicidal activity, and computational studies of isatin derivatives.

  Journal of agricultural and food chemistry 20110928

• 5-Fluoro-1-(4-meth-oxy-benz-yl)indoline-2,3-dione.

  Acta crystallographica. Section E, Structure reports online 20110701

• 5''-(4-Chloro-benzyl-idene)-4'-(4-chloro-phen-yl)-5-fluoro-1',1''-dimethyl-indoline-3-spiro-2'-pyrrolidine-3'-spiro-3''-piperidine-2,4''-dione.

  Acta crystallographica. Section E, Structure reports online 20110401

• Synthesis of 3,3-diindolyl oxyindoles efficiently catalysed by FeCl3 and their in vitro evaluation for anticancer activity.

  Bioorganic & medicinal chemistry letters 20100901

• QSAR study of isatin analogues as in vitro anti-cancer agents.

  European journal of medicinal chemistry 20100301

• Synthesis and Pharmacological Evaluation of Novel Schiff Base Analogues of 3-(4-amino) Phenylimino) 5-fluoroindolin-2-one.

  Journal of young pharmacists : JYP 20100101

• Investigation of trypanothione reductase as a drug target in Trypanosoma brucei.

  ChemMedChem 20091207

• N'-(5-Fluoro-2-oxo-2,3-dihydro-1H-indol-3-yl-idene)benzene-sulfono-hydrazide.

  Acta crystallographica. Section E, Structure reports online 20080501

• Synthesis and structure-antituberculosis activity relationship of 1H-indole-2,3-dione derivatives.

  Bioorganic & medicinal chemistry 20070901

• Synthesis, antibacterial, antifungal and antiviral activity evaluation of some new bis-Schiff bases of isatin and their derivatives.

  Molecules (Basel, Switzerland) 20070807

• Biological targets for isatin and its analogues: Implications for therapy.

  Biologics : targets & therapy 20070601

• Selective inhibition of carboxylesterases by isatins, indole-2,3-diones.

  Journal of medicinal chemistry 20070419

• In vitro cytotoxicity evaluation of some substituted isatin derivatives.

  Bioorganic & medicinal chemistry 20070115

• Synthesis of some new bis-Schiff bases of isatin and 5-fluoroisatin in a water suspension medium.

  Molecules (Basel, Switzerland) 20060131

• Synthesis and evaluation of isatins and thiosemicarbazone derivatives against cruzain, falcipain-2 and rhodesain.

  Bioorganic & medicinal chemistry letters 20031020

• Synthesis and antiviral evaluation of isatin ribonucleosides.

  Nucleosides, nucleotides & nucleic acids 20020101