443-88-9 | 2,6-Dimethylfluorobenzene

Packsize	Purity	Availability	Price	Discounted Price
5g	95%	in stock	$19.00	$13.00
25g	95%	in stock	$57.00	$40.00
100g	98%	in stock	$203.00	$142.00
500g	98%	in stock	$760.00	$532.00

Description

• Catalog Number: AB60708
• Chemical Name: 2,6-Dimethylfluorobenzene
• CAS Number: 443-88-9
• Molecular Formula: C8H9F
• Molecular Weight: 124.1555
• MDL Number: MFCD02083292
• SMILES: Cc1cccc(c1F)C

Computed Properties

• Complexity: 80.6
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 9
• Hydrogen Bond Acceptor Count: 1
• XLogP3: 2.8

Upstream Synthesis Route

2-Fluoro-1,3-dimethylbenzene, also known as ortho-fluoroxylene, plays a crucial role in chemical synthesis as a versatile building block. This compound is widely utilized in organic chemistry for the preparation of various important chemicals and pharmaceuticals. Its unique structure with a fluorine atom attached to the benzene ring and two methyl groups allows for specific reactivity and selectivity in reactions.In chemical synthesis, 2-fluoro-1,3-dimethylbenzene can be used as a starting material for the synthesis of various fluorinated compounds. The presence of the fluorine atom imparts significant changes in the physicochemical properties of the resulting molecules, making them valuable in pharmaceuticals, agrochemicals, and materials science. By undergoing various functionalization reactions, ortho-fluoroxylene can be transformed into a range of derivatives with diverse applications.One common application of 2-fluoro-1,3-dimethylbenzene is in the production of specialty chemicals such as fluorinated polymers, which have unique properties like chemical resistance and thermal stability. Additionally, this compound can be utilized in the synthesis of pharmaceutical intermediates, where the fluorine substituent can enhance the biological activity and metabolic stability of the final drug molecules.Overall, the strategic placement of a fluorine atom on the benzene ring of 2-fluoro-1,3-dimethylbenzene makes it a valuable building block in chemical synthesis, offering opportunities for the creation of novel compounds with tailored properties for various industrial applications.

Literature

• Spectroscopic observation of jet-cooled 2-fluoro-m-xylyl radical.

  The Journal of chemical physics 20120114