445-27-2 | 2'-Fluoroacetophenone

Packsize	Purity	Availability	Price	Discounted Price
5g	99%	in stock	$6.00	$4.00
10g	99%	in stock	$8.00	$5.00
25g	99%	in stock	$15.00	$10.00
100g	99%	in stock	$36.00	$25.00
250g	99%	in stock	$72.00	$50.00
500g	99%	in stock	$86.00	$60.00

Description

• Catalog Number: AB60866
• Chemical Name: 2'-Fluoroacetophenone
• CAS Number: 445-27-2
• Molecular Formula: C8H7FO
• Molecular Weight: 138.139
• MDL Number: MFCD00000320
• SMILES: CC(=O)c1ccccc1F
• NSC Number: 88297

Computed Properties

• Complexity: 133
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 10
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• XLogP3: 1.6

Upstream Synthesis Route

1-(2-Fluorophenyl)ethanone, commonly known in the chemical world for its versatility and utility, is a key component in various chemical synthesis processes. This organic compound serves as a crucial building block in the creation of numerous valuable chemical derivatives due to its unique structural properties and reactivity.One of the primary applications of 1-(2-Fluorophenyl)ethanone in chemical synthesis is its role as a key intermediate in the pharmaceutical industry. Its ability to undergo various functional group transformations makes it an essential precursor in the synthesis of biologically active compounds, pharmaceuticals, and agrochemicals. By incorporating this compound into complex chemical reactions, researchers can access a wide range of valuable products with diverse applications.Furthermore, 1-(2-Fluorophenyl)ethanone is also utilized in the preparation of specialty chemicals, such as fragrances, dyes, and polymers. The presence of the fluorine atom in its structure imparts unique properties to the final products, making them highly sought after in the industry. Additionally, this compound can be used in the development of new materials and advanced organic synthesis methodologies, showcasing its significance in pushing the boundaries of chemical research and innovation.Overall, the application of 1-(2-Fluorophenyl)ethanone in chemical synthesis highlights its pivotal role as a versatile and valuable compound in the field of chemistry, providing essential building blocks for the development of various industrially important products and materials.

Literature

• Total synthesis of ascididemin via anionic cascade ring closure.

  Chemical communications (Cambridge, England) 20120918

• Estimations of excited state dipole moments of conformers in some o-substituted acetophenones by solvato-chromic shifts.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20040601

• Biocatalytic reduction of ketones by a semi-continuous flow process using supercritical carbon dioxide.

  Chemical communications (Cambridge, England) 20030521