4506-66-5 | 1,2,4,5-Benzenetetramine tetrahydrochloride

Packsize	Purity	Availability	Price	Discounted Price
10mg	97%	in stock	$11.00	$8.00
50mg	97%	in stock	$13.00	$9.00
250mg	97%	in stock	$23.00	$16.00
1g	97%	in stock	$29.00	$20.00
5g	97%	in stock	$73.00	$51.00
10g	97%	in stock	$146.00	$102.00
25g	97%	in stock	$363.00	$254.00

Description

• Catalog Number: AB49921
• Chemical Name: 1,2,4,5-Benzenetetramine tetrahydrochloride
• CAS Number: 4506-66-5
• Molecular Formula: C6H14Cl4N4
• Molecular Weight: 284.01416
• MDL Number: MFCD00012970
• SMILES: Nc1cc(N)c(cc1N)N.Cl.Cl.Cl.Cl

Computed Properties

• Complexity: 90.3
• Covalently-Bonded Unit Count: 5
• Heavy Atom Count: 14
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 8

Literature

• Thrombin-dependent modulation of β1-integrin-mediated signaling up-regulates prolidase and HIF-1α through p-FAK in colorectal cancer cells.

  Molecular and cellular biochemistry 20120201

• Copper deficiency induced emphysema is associated with focal adhesion kinase inactivation.

  PloS one 20120101

• Targeting the MYCN effector, FAK, in neuroblastoma.

  Cell cycle (Georgetown, Tex.) 20100315

• Inhibition of focal adhesion kinase decreases tumor growth in human neuroblastoma.

  Cell cycle (Georgetown, Tex.) 20100301

• A novel small molecule inhibitor of FAK decreases growth of human pancreatic cancer.

  Cell cycle (Georgetown, Tex.) 20090801

• A small molecule inhibitor, 1,2,4,5-benzenetetraamine tetrahydrochloride, targeting the y397 site of focal adhesion kinase decreases tumor growth.

  Journal of medicinal chemistry 20081211