4522-35-4 | 3-Iodopyrazole

Packsize	Purity	Availability	Price	Discounted Price
250mg	98%	in stock	$6.00	$4.00
1g	98%	in stock	$8.00	$5.00
5g	98%	in stock	$20.00	$14.00
10g	98%	in stock	$33.00	$23.00
25g	98%	in stock	$56.00	$39.00
100g	98%	in stock	$159.00	$111.00

Description

• Catalog Number: AA03374
• Chemical Name: 3-Iodopyrazole
• CAS Number: 4522-35-4
• Molecular Formula: C3H3IN2
• Molecular Weight: 193.9738
• MDL Number: MFCD12022324
• SMILES: Ic1cc[nH]n1

Computed Properties

• Complexity: 48.1
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 6
• Hydrogen Bond Acceptor Count: 1
• Hydrogen Bond Donor Count: 1
• XLogP3: 0.9

Upstream Synthesis Route

3-Iodo-1H-pyrazole is a versatile building block in chemical synthesis due to its unique structural properties and reactivity. This compound serves as a powerful nucleophile in organic reactions, allowing for the formation of new carbon-carbon or carbon-heteroatom bonds. In particular, 3-Iodo-1H-pyrazole is commonly used in the synthesis of pharmaceuticals, agrochemicals, and materials.One key application of 3-Iodo-1H-pyrazole is in the preparation of heterocyclic compounds. By reacting with different electrophiles or coupling partners, this compound can be utilized to introduce the pyrazole ring motif into molecular structures. This enables the modulation of biological activity or tuning of physical properties in target molecules.In addition, 3-Iodo-1H-pyrazole can participate in metal-catalyzed cross-coupling reactions, such as Suzuki-Miyaura or Stille couplings, leading to the formation of complex organic frameworks. These reactions offer a powerful means to construct carbon-carbon bonds efficiently and selectively, facilitating the synthesis of structurally diverse compounds.Furthermore, 3-Iodo-1H-pyrazole is valued for its role as a halogenated building block, enabling further functionalization through substitution or elimination reactions. This flexibility in chemical modifications broadens the scope of synthetic routes and provides access to a wide range of derivatives with tailored properties.Overall, the strategic use of 3-Iodo-1H-pyrazole in chemical synthesis offers synthetic chemists a versatile tool for designing and accessing novel molecules with potential applications in various fields of chemistry and beyond.