453-20-3 | 3-Hydroxytetrahydrofuran

Packsize	Purity	Availability	Price	Discounted Price
5g	98%	in stock	$10.00	$7.00
10g	98%	in stock	$13.00	$9.00
25g	98%	in stock	$24.00	$17.00
100g	98%	in stock	$55.00	$38.00

Description

• Catalog Number: AB65148
• Chemical Name: 3-Hydroxytetrahydrofuran
• CAS Number: 453-20-3
• Molecular Formula: C4H8O2
• Molecular Weight: 88.1051
• MDL Number: MFCD00005374
• SMILES: OC1COCC1
• NSC Number: 71875

Computed Properties

• Complexity: 44.8
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 6
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 1
• Undefined Atom Stereocenter Count: 1
• XLogP3: -0.4

Upstream Synthesis Route

3-Hydroxytetrahydrofuran, commonly referred to as 3-HTHF, is a valuable compound in chemical synthesis due to its versatile applications. This molecule serves as a key building block in the creation of various pharmaceuticals, agrochemicals, and fine chemicals. Its unique structure allows it to participate in reactions that lead to the formation of complex molecular structures with high efficiency. By acting as a starting material or intermediate, 3-HTHF enables chemists to access a wide range of functionalized derivatives with different properties and functionalities. Its use in the synthesis of bioactive compounds, such as antiviral agents and enzyme inhibitors, has garnered significant attention in the research community. Additionally, the ability of 3-HTHF to undergo selective chemical transformations makes it a valuable tool for achieving specific structural modifications in target molecules. Overall, the incorporation of 3-Hydroxytetrahydrofuran into chemical synthesis processes opens up new possibilities for the development of novel compounds with potential applications in various industries.

Literature

• Molecular Basis for Drug Resistance in HIV-1 Protease.

  Viruses 20101101

• Amine-directed hydroboration: scope and limitations.

  Journal of the American Chemical Society 20080709

• Angle-resolved photoelectron spectroscopy of randomly oriented 3-hydroxytetrahydrofuran enantiomers.

  Chemphyschem : a European journal of chemical physics and physical chemistry 20050613

• Excitation, ionization, and fragmentation of chiral molecules in asymmetric microenvironments: a mass-resolved R2PI spectroscopic study.

  The journal of physical chemistry. A 20050310

• Modeling deoxyribose radicals by neutralization-reionization mass spectrometry. Part 2. Preparation, dissociations, and energetics of 3-hydroxyoxolan-3-yl radical and cation.

  Journal of the American Society for Mass Spectrometry 20040701