4546-55-8 | N6-Benzoyladenosine

Packsize	Purity	Availability	Price	Discounted Price
1g	95%	in stock	$6.00	$4.00
5g	95%	in stock	$8.00	$5.00
10g	95%	in stock	$14.00	$10.00
25g	95%	in stock	$19.00	$13.00
100g	95%	in stock	$70.00	$49.00

Description

• Catalog Number: AB49078
• Chemical Name: N6-Benzoyladenosine
• CAS Number: 4546-55-8
• Molecular Formula: C17H17N5O5
• Molecular Weight: 371.3474
• MDL Number: MFCD27977441
• SMILES: OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2NC(=O)c1ccccc1

Computed Properties

• Complexity: 534
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 4
• Heavy Atom Count: 27
• Hydrogen Bond Acceptor Count: 8
• Hydrogen Bond Donor Count: 4
• Rotatable Bond Count: 4
• XLogP3: -0.1

Upstream Synthesis Route

N6-Benzoyladenosine is a versatile compound commonly used in chemical synthesis for its ability to act as a protecting group for the N6 amino group of adenosine. This functional group plays a crucial role in modulating reactivity and selectivity during the synthesis of nucleosides, nucleotides, and other bioactive compounds. By shielding the N6 amino group, N6-Benzoyladenosine enables specific site-selective reactions to take place without interference from other functional groups present on the molecule. Additionally, this compound can be selectively removed under mild conditions, allowing for the controlled manipulation of chemical structures in a strategic manner. Its application in chemical synthesis contributes to the development of novel pharmaceuticals, nucleic acid analogs, and other valuable molecules with tailored properties and functions.

Literature

• PDE4 inhibitor, roflumilast protects cardiomyocytes against NO-induced apoptosis via activation of PKA and Epac dual pathways.

  Cellular signalling 20080501