458-37-7 | (1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione

Packsize	Purity	Availability	Price	Discounted Price
5g	98%	in stock	$6.00	$4.00
10g	98%	in stock	$7.00	$5.00
25g	98%	in stock	$10.00	$7.00
100g	98%	in stock	$31.00	$22.00
500g	98%	in stock	$112.00	$79.00

Description

• Catalog Number: AB51052
• Chemical Name: (1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione
• CAS Number: 458-37-7
• Molecular Formula: C21H20O6
• Molecular Weight: 368.3799
• MDL Number: MFCD00008365
• SMILES: COc1cc(/C=C/C(=O)CC(=O)/C=C/c2ccc(c(c2)OC)O)ccc1O

Computed Properties

• Complexity: 507
• Covalently-Bonded Unit Count: 1
• Defined Bond Stereocenter Count: 2
• Heavy Atom Count: 27
• Hydrogen Bond Acceptor Count: 6
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 8
• XLogP3: 3.2

Literature

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• Novel carbocyclic curcumin analog CUR3d modulates genes involved in multiple apoptosis pathways in human hepatocellular carcinoma cells.

  Chemico-biological interactions 20151205

• Cadmium induces matrix metalloproteinase-9 expression via ROS-dependent EGFR, NF-кB, and AP-1 pathways in human endothelial cells.

  Toxicology 20151202

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  Neurotoxicology 20150901

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• Inhibition of tobacco smoke-induced bladder MAPK activation and epithelial-mesenchymal transition in mice by curcumin.

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  BMC cancer 20150101

• Nrf2 knockout attenuates the anti-inflammatory effects of phenethyl isothiocyanate and curcumin.

  Chemical research in toxicology 20141215

• Suppression of alpha-tocopherol ether-linked acetic acid in VEGF-induced angiogenesis and the possible mechanisms in human umbilical vein endothelial cells.

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  Toxicology letters 20141118

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• Protective effects of intranasal curcumin on paraquot induced acute lung injury (ALI) in mice.

  Environmental toxicology and pharmacology 20141101

• Tetrachloro-p-benzoquinone induces hepatic oxidative damage and inflammatory response, but not apoptosis in mouse: the prevention of curcumin.

  Toxicology and applied pharmacology 20141015

• Curcumin modulates miR-19/PTEN/AKT/p53 axis to suppress bisphenol A-induced MCF-7 breast cancer cell proliferation.

  Phytotherapy research : PTR 20141001

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• Unraveling the mechanism of neuroprotection of curcumin in arsenic induced cholinergic dysfunctions in rats.

  Toxicology and applied pharmacology 20140915

• Pretreatment with turmeric modulates the inhibitory influence of cisplatin and paclitaxel on CYP2E1 and CYP3A1/2 in isolated rat hepatic microsomes.

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  ACS chemical neuroscience 20140820

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  Toxicology letters 20140804

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• Curcumin and (-)-epigallocatechin-3-gallate attenuate acrylamide-induced proliferation in HepG2 cells.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20140401

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• Curcumin protects against cadmium-induced vascular dysfunction, hypertension and tissue cadmium accumulation in mice.

  Nutrients 20140301

• Regulation of death induction and chemosensitizing action of 3-bromopyruvate in myeloid leukemia cells: energy depletion, oxidative stress, and protein kinase activity modulation.

  The Journal of pharmacology and experimental therapeutics 20140201

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  Toxicology and applied pharmacology 20140101

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  Redox biology 20140101

• Curcumin and vitamin E protect against adverse effects of benzo[a]pyrene in lung epithelial cells.

  PloS one 20140101

• Areca nut components affect COX-2, cyclin B1/cdc25C and keratin expression, PGE2 production in keratinocyte is related to reactive oxygen species, CYP1A1, Src, EGFR and Ras signaling.

  PloS one 20140101

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  Molecular pain 20140101

• Tetrahydrocurcumin protects against cadmium-induced hypertension, raised arterial stiffness and vascular remodeling in mice.

  PloS one 20140101

• Protective effect of curcumin against formaldehyde-induced genotoxicity in A549 Cell Lines.

  Journal of applied toxicology : JAT 20131201

• Curcumin analogue identified as hyaluronan export inhibitor by virtual docking to the ABC transporter MRP5.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20131201

• Acute effects of diesel exhaust particles and cisplatin on oxidative stress in cultured human kidney (HEK 293) cells, and the influence of curcumin thereon.

  Toxicology in vitro : an international journal published in association with BIBRA 20131201

• Curcumin analog 1, 5-bis (2-trifluoromethylphenyl)-1, 4-pentadien-3-one exhibits enhanced ability on Nrf2 activation and protection against acrolein-induced ARPE-19 cell toxicity.

  Toxicology and applied pharmacology 20131101

• Zinc(II)-curcumin accelerates the healing of acetic acid-induced chronic gastric ulcers in rats by decreasing oxidative stress and downregulation of matrix metalloproteinase-9.

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  Pharmacological research 20131001

• Curcumin ameliorates intrahepatic angiogenesis and capillarization of the sinusoids in carbon tetrachloride-induced rat liver fibrosis.

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• Curcumin attenuates arsenic-induced hepatic injuries and oxidative stress in experimental mice through activation of Nrf2 pathway, promotion of arsenic methylation and urinary excretion.

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  Cancer prevention research (Philadelphia, Pa.) 20130901

• Curcumin inhibits oxLDL-induced CD36 expression and foam cell formation through the inhibition of p38 MAPK phosphorylation.

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• Interaction of inflammatory and anti-inflammatory responses in microglia by Staphylococcus aureus-derived lipoteichoic acid.

  Toxicology and applied pharmacology 20130515

• Induction of apoptosis by curcumin in murine myelomonocytic leukemia WEHI-3 cells is mediated via endoplasmic reticulum stress and mitochondria-dependent pathways.

  Environmental toxicology 20130501

• AhR- and NF-κB-dependent induction of interleukin-6 by co-exposure to the environmental contaminant benzanthracene and the cytokine tumor necrosis factor-α in human mammary MCF-7 cells.

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  Biological trace element research 20130401

• Bisphenol-A-induced inactivation of the p53 axis underlying deregulation of proliferation kinetics, and cell death in non-malignant human breast epithelial cells.

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  Neurotoxicology 20130301

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  Journal of breast cancer 20130301

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  Chemico-biological interactions 20130125

• Intra- and extracellular antioxidant capacities of the new water-soluble form of curcumin (NDS27) on stimulated neutrophils and HL-60 cells.

  Chemico-biological interactions 20130125

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  Food chemistry 20130115

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• Curcumin reduces cisplatin-induced neurotoxicity in NGF-differentiated PC12 cells.

  Neurotoxicology 20130101

• Synthesis, antimalarial activity and cytotoxic potential of new monocarbonyl analogues of curcumin.

  Bioorganic & medicinal chemistry letters 20130101

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  Radiation oncology (London, England) 20130101

• Cytotoxic effects of curcumin in human retinal pigment epithelial cells.

  PloS one 20130101

• Curcumin protects human keratinocytes against inorganic arsenite-induced acute cytotoxicity through an NRF2-dependent mechanism.

  Oxidative medicine and cellular longevity 20130101

• Ouabain, a cardiac glycoside, inhibits the Fanconi anemia/BRCA pathway activated by DNA interstrand cross-linking agents.

  PloS one 20130101

• Multi-layer polymeric implants for sustained release of chemopreventives.

  Cancer letters 20121229

• Short curcumin treatment modulates oxidative stress, arginase activity, aberrant crypt foci, and TGF-β1 and HES-1 transcripts in 1,2-dimethylhydrazine-colon carcinogenesis in mice.

  Toxicology 20121216

• Discovering Bisdemethoxycurcumin from Curcuma longa rhizome as a potent small molecule inhibitor of human pancreatic α-amylase, a target for type-2 diabetes.

  Food chemistry 20121215

• Perifosine sensitizes curcumin-induced anti-colorectal cancer effects by targeting multiple signaling pathways both in vivo and in vitro.

  International journal of cancer 20121201

• Bioactive derivatives of curcumin attenuate cataract formation in vitro.

  Chemical biology & drug design 20121201

• Formulation and evaluation of microemulsion-based in situ ion-sensitive gelling systems for intranasal administration of curcumin.

  Journal of drug targeting 20121201

• The role of electron-transfer and H-atom donation on the superb antioxidant activity and free radical reaction of curcumin.

  Food chemistry 20121201

• Temperature-dependent stability and DPPH scavenging activity of liposomal curcumin at pH 7.0.

  Food chemistry 20121201

• Chemoprevention of pancreatic cancer using solid-lipid nanoparticulate delivery of a novel aspirin, curcumin and sulforaphane drug combination regimen.

  International journal of oncology 20121201

• Curcumin induces apoptosis of triple-negative breast cancer cells by inhibition of EGFR expression.

  Molecular medicine reports 20121201

• Combination treatment with photodynamic therapy and curcumin induces mitochondria-dependent apoptosis in AMC-HN3 cells.

  International journal of oncology 20121201

• Simultaneous mitochondrial Ca(2+) overload and proteasomal inhibition are responsible for the induction of paraptosis in malignant breast cancer cells.

  Cancer letters 20121128

• In vitro antioxidant and anti-inflammatory activities of 1-dehydro-[6]-gingerdione, 6-shogaol, 6-dehydroshogaol and hexahydrocurcumin.

  Food chemistry 20121115

• Curcumin reduces the cardiac ischemia-reperfusion injury: involvement of the toll-like receptor 2 in cardiomyocytes.

  The Journal of nutritional biochemistry 20121101

• Differential regulation of CD4(+) T helper cell responses by curcumin in experimental autoimmune encephalomyelitis.

  The Journal of nutritional biochemistry 20121101

• A randomized, pilot study to assess the efficacy and safety of curcumin in patients with active rheumatoid arthritis.

  Phytotherapy research : PTR 20121101

• Identification of antitumor constituents in curcuminoids from Curcuma longa L. based on the composition-activity relationship.

  Journal of pharmaceutical and biomedical analysis 20121101

• Apoptosis signal-regulating kinase 1 is mediated in TNF-α-induced CCL2 expression in human synovial fibroblasts.

  Journal of cellular biochemistry 20121101

• Curcumin and vitamin E modulate hepatic antioxidant gene expression in PTU-induced hypothyroid rats.

  Molecular biology reports 20121101

• Analytical methods to determine the comparative DNA binding studies of curcumin-Cu(II) complexes.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20121101

• Curcumin extract for prevention of type 2 diabetes.

  Diabetes care 20121101

• Potential impact of curcumin and taurine on human hepatoma cells using Huh-7 cell line.

  Clinical biochemistry 20121101

• Curcumin produces antidepressant effects via activating MAPK/ERK-dependent brain-derived neurotrophic factor expression in the amygdala of mice.

  Behavioural brain research 20121101

• Intraductal administration of a polymeric nanoparticle formulation of curcumin (NanoCurc) significantly attenuates incidence of mammary tumors in a rodent chemical carcinogenesis model: Implications for breast cancer chemoprevention in at-risk populations.

  Carcinogenesis 20121101

• Dietary polyphenols and mechanisms of osteoarthritis.

  The Journal of nutritional biochemistry 20121101

• Curcumin, an active component of turmeric in the prevention and treatment of ulcerative colitis: preclinical and clinical observations.

  Food & function 20121101

• Curcumin's pre-incubation temperature affects its inhibitory potency toward amyloid fibrillation and fibril-induced cytotoxicity of lysozyme.

  Biochimica et biophysica acta 20121101

• One pot synthesis, structural and spectral analysis of some symmetrical curcumin analogues catalyzed by calcium oxide under microwave irradiation.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20121101

• ApoE3 mediated polymeric nanoparticles containing curcumin: apoptosis induced in vitro anticancer activity against neuroblastoma cells.

  International journal of pharmaceutics 20121101

• Curcumin mediated epigenetic modulation inhibits TREM-1 expression in response to lipopolysaccharide.

  The international journal of biochemistry & cell biology 20121101

• In situ injectable nano-composite hydrogel composed of curcumin, N,O-carboxymethyl chitosan and oxidized alginate for wound healing application.

  International journal of pharmaceutics 20121101

• Curcumin inhibits HCV replication by induction of heme oxygenase-1 and suppression of AKT.

  International journal of molecular medicine 20121101

• Curcumin ameloriates heat stress via inhibition of oxidative stress and modulation of Nrf2/HO-1 pathway in quail.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20121101

• A plant cell-based system that predicts aβ42 misfolding: potential as a drug discovery tool for Alzheimer's disease.

  Molecular genetics and metabolism 20121101

• Enhanced CD36 expression changes the role of Nrf2 activation from anti-atherogenic to pro-atherogenic in apoE-deficient mice.

  Atherosclerosis 20121101

• Emerging role of nanocarriers to increase the solubility and bioavailability of curcumin.

  Expert opinion on drug delivery 20121101

• Autophosphorylation activation and inhibition by curcumin of the epidermal growth factor receptor reconstituted in liposomes.

  Journal of molecular recognition : JMR 20121101

• New ruthenium(II)-letrozole complexes as anticancer therapeutics.

  Journal of medicinal chemistry 20121025

• Interaction of over-the-counter drugs with curcumin: influence on stability and bioactivities in intestinal cells.

  Journal of agricultural and food chemistry 20121024

• The effect of curcumin on human bronchial epithelial cells exposed to fine particulate matter: a predictive analysis.

  Molecules (Basel, Switzerland) 20121022

• Femtosecond transient absorption spectroscopy of copper(II)-curcumin complexes.

  Physical chemistry chemical physics : PCCP 20121021

• Constitutive autotaxin transcription by Nmyc-amplified and non-amplified neuroblastoma cells is regulated by a novel AP-1 and SP-mediated mechanism and abrogated by curcumin.

  FEBS letters 20121019

• Curcumin for maintenance of remission in ulcerative colitis.

  The Cochrane database of systematic reviews 20121017

• Novel lipid based oral formulation of curcumin: development and optimization by design of experiments approach.

  International journal of pharmaceutics 20121015

• Curcumin is an inhibitor of calcium/calmodulin dependent protein kinase II.

  Bioorganic & medicinal chemistry 20121015

• Antioxidant properties of Mannich bases.

  Bioorganic & medicinal chemistry letters 20121015

• Curcumin prevents diabetic cardiomyopathy in streptozotocin-induced diabetic rats: possible involvement of PKC-MAPK signaling pathway.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20121009

• Role of curcumin on the determination of the critical micellar concentration by absorbance, fluorescence and fluorescence anisotropy techniques.

  Journal of photochemistry and photobiology. B, Biology 20121003

• Antiapoptotic and proliferative activity of curcumin on ovarian follicles in mice exposed to whole body ionizing radiation.

  Toxicology and industrial health 20121001

• Improvement of sulphur mustard-induced chronic pruritus, quality of life and antioxidant status by curcumin: results of a randomised, double-blind, placebo-controlled trial.

  The British journal of nutrition 20121001

• Curcumin protects against thioacetamide-induced hepatic fibrosis by attenuating the inflammatory response and inducing apoptosis of damaged hepatocytes.

  The Journal of nutritional biochemistry 20121001

• Effect of curcumin and quercetin on lysosomal enzyme activities in streptozotocin-induced diabetic rats.

  Clinical nutrition (Edinburgh, Scotland) 20121001

• Rescue of a pathogenic mutant human glucagon receptor by pharmacological chaperones.

  Journal of molecular endocrinology 20121001

• Knockdown survivin expression reduces the efficacy of curcumin treatment in hepatocellular carcinoma cells.

  Annals of surgical oncology 20121001

• Comment on: Monoclonal gammopathy of undetermined significance, smoldering multiple myeloma, and curcumin: a randomized, double-blind placebo-controlled crossover 4g study and an open-label 8g extension study.

  American journal of hematology 20121001

• Chronic treatment with curcumin enhances methamphetamine locomotor sensitization and cue-induced reinstatement of methamphetamine self-administration.

  Pharmacology, biochemistry, and behavior 20121001

• Curcumin-induced heme oxygenase-1 expression plays a negative role for its anti-cancer effect in bladder cancers.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20121001

• Alendronate coated poly-lactic-co-glycolic acid (PLGA) nanoparticles for active targeting of metastatic breast cancer.

  Biomaterials 20121001

• Paclitaxel delivery using carrier made from curcumin derivative: synergism between carrier and the loaded drug for effective cancer treatment.

  Journal of pharmaceutical sciences 20121001

• Fabrication and characterization of curcumin-releasing silk fibroin scaffold.

  Journal of biomedical materials research. Part B, Applied biomaterials 20121001

• Effects of curcumin on bleomycin‑induced oxidative stress in malignant testicular germ cell tumors.

  Molecular medicine reports 20121001

• Carnosic acid inhibits the growth of ER-negative human breast cancer cells and synergizes with curcumin.

  Fitoterapia 20121001

• Curcumin attenuates rat thoracic aortic aneurysm formation by inhibition of the c-Jun N-terminal kinase pathway and apoptosis.

  Nutrition (Burbank, Los Angeles County, Calif.) 20121001

• Induction of apoptosis and reduction of MMP gene expression in the U373 cell line by polyphenolics in Aronia melanocarpa and by curcumin.

  Oncology reports 20121001

• Response to Vermorken et al--curcumin and free light chains.

  American journal of hematology 20121001

• Targeting CSCs within the tumor microenvironment for cancer therapy: a potential role of mesenchymal stem cells.

  Expert opinion on therapeutic targets 20121001

• Curcumin: a potential candidate for matrix metalloproteinase inhibitors.

  Expert opinion on therapeutic targets 20121001

• Sustained wound healing activity of curcumin loaded oleic acid based polymeric bandage in a rat model.

  Molecular pharmaceutics 20121001

• p300/CBP acetyl transferases interact with and acetylate the nucleotide excision repair factor XPG.

  DNA repair 20121001

• Curcumin potentiates the antitumor effects of 5-FU in treatment of esophageal squamous carcinoma cells through downregulating the activation of NF-κB signaling pathway in vitro and in vivo.

  Acta biochimica et biophysica Sinica 20121001

• Dietary modification of metabolic pathways via nuclear hormone receptors.

  Cell biochemistry and function 20121001

• Curcumin protects against staurosporine toxicity in rat neurons.

  Neuroscience bulletin 20121001

• Tissue distribution of (Lipocurc™) liposomal curcumin and tetrahydrocurcumin following two- and eight-hour infusions in Beagle dogs.

  Anticancer research 20121001

• Infusion pharmacokinetics of Lipocurc™ (liposomal curcumin) and its metabolite tetrahydrocurcumin in Beagle dogs.

  Anticancer research 20121001

• Curcumin inhibits Rift Valley fever virus replication in human cells.

  The Journal of biological chemistry 20120928

• Effects of curcumin on levels of nitric oxide synthase and AQP-4 in a rat model of hypoxia-ischemic brain damage.

  Brain research 20120926

• Curcumin-cyclodextrin complexes potentiate gemcitabine effects in an orthotopic mouse model of lung cancer.

  British journal of cancer 20120925

• Excited-state dynamics of bis-dehydroxycurcumin carboxylic acid, a water-soluble derivative of the photosensitizer curcumin.

  The journal of physical chemistry. A 20120920

• Quercetin, resveratrol, and curcumin are indirect activators of the aryl hydrocarbon receptor (AHR).

  Chemical research in toxicology 20120917

• A synthetic compound, 1,5-bis(2-methoxyphenyl)penta-1,4-dien-3-one (B63), induces apoptosis and activates endoplasmic reticulum stress in non-small cell lung cancer cells.

  International journal of cancer 20120915

• Polymeric black tea polyphenols modulate the localization and activity of 12-O-tetradecanoylphorbol-13-acetate-mediated kinases in mouse skin: mechanisms of their anti-tumor-promoting action.

  Free radical biology & medicine 20120915

• Chemical chaperones curcumin and 4-phenylbutyric acid improve secretion of mutant factor H R127H by fibroblasts from a factor H-deficient patient.

  Journal of immunology (Baltimore, Md. : 1950) 20120915

• Curcumin suppresses the TPA-induced invasion through inhibition of PKCα-dependent MMP-expression in MCF-7 human breast cancer cells.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20120915

• Beneficial effects of curcumin on GFAP filament organization and down-regulation of GFAP expression in an in vitro model of Alexander disease.

  Experimental cell research 20120910

• Cycle arrest and apoptosis in MDA-MB-231/Her2 cells induced by curcumin.

  European journal of pharmacology 20120905

• Synthesis of novel biodegradable methoxy poly(ethylene glycol)-zein micelles for effective delivery of curcumin.

  Molecular pharmaceutics 20120904

• Curcumin: a novel Stat3 pathway inhibitor for chemoprevention of lung cancer.

  European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 20120901

• Pulmonary administration of a water-soluble curcumin complex reduces severity of acute lung injury.

  American journal of respiratory cell and molecular biology 20120901

• Neuroprotective effect of curcuminoids against inflammation-mediated dopaminergic neurodegeneration in the MPTP model of Parkinson's disease.

  Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 20120901

• Molecular evidence of curcumin-induced apoptosis in the filarial worm Setaria cervi.

  Parasitology research 20120901

• Curcumin loaded mixed micelles composed of Pluronic P123 and F68: preparation, optimization and in vitro characterization.

  Colloids and surfaces. B, Biointerfaces 20120901

• Evaluation of naturally occurring curcuminoids and related compounds against mosquito larvae.

  Acta tropica 20120901

• Oxidative stress induced by curcumin promotes the death of cutaneous T-cell lymphoma (HuT-78) by disrupting the function of several molecular targets.

  Molecular cancer therapeutics 20120901

• LRRK2 kinase activity mediates toxic interactions between genetic mutation and oxidative stress in a Drosophila model: suppression by curcumin.

  Neurobiology of disease 20120901

• Protective effects of curcumin against hepatic fibrosis induced by carbon tetrachloride: modulation of high-mobility group box 1, Toll-like receptor 4 and 2 expression.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120901

• Amphiphilic peptide carrier for the combined delivery of curcumin and plasmid DNA into the lungs.

  Biomaterials 20120901

• Curcumin ameliorates mitochondrial dysfunction associated with inhibition of gluconeogenesis in free fatty acid-mediated hepatic lipoapoptosis.

  International journal of molecular medicine 20120901

• In vitro cytogenetic and genotoxic effects of curcumin on human peripheral blood lymphocytes.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120901

• Curcumin suppresses HIF1A synthesis and VEGFA release in pituitary adenomas.

  The Journal of endocrinology 20120901

• Curcumin inhibits suppressive capacity of naturally occurring CD4+CD25+ regulatory T cells in mice in vitro.

  International immunopharmacology 20120901

• Positive effect of curcumin on inflammation and mitochondrial dysfunction in obese mice with liver steatosis.

  International journal of molecular medicine 20120901

• The impact of curcumin on breast cancer.

  Integrative biology : quantitative biosciences from nano to macro 20120901

• Dose escalation and pharmacokinetic study of nanoparticle curcumin… by Kanai et al., CCP 69:65-70, 2012.

  Cancer chemotherapy and pharmacology 20120901

• HDAC inhibitors augmented cell migration and metastasis through induction of PKCs leading to identification of low toxicity modalities for combination cancer therapy.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20120901

• Curcumin analogues with potent and selective anti-proliferative activity on acute promyelocytic leukemia: involvement of accumulated misfolded nuclear receptor co-repressor (N-CoR) protein as a basis for selective activity.

  ChemMedChem 20120901

• Antagonism between curcumin and the topoisomerase II inhibitor etoposide: a study of DNA damage, cell cycle regulation and death pathways.

  Cancer biology & therapy 20120901

• Attenuation of endothelin-1-induced PKB and ERK1/2 signaling, as well as Egr-1 expression, by curcumin in A-10 vascular smooth muscle cells.

  Canadian journal of physiology and pharmacology 20120901

• The effect of curcumin on lung injuries in a rat model induced by aspirating gastrointestinal decontamination agents.

  Journal of pediatric surgery 20120901

• The cellular uptake and cytotoxic effect of curcuminoids on breast cancer cells.

  Taiwanese journal of obstetrics & gynecology 20120901

• Phase behavior and oral bioavailability of amorphous Curcumin.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20120830

• Photoinactivation of Staphylococcus epidermidis biofilms and suspensions by the hydrophobic photosensitizer curcumin--effect of selected nanocarrier: studies on curcumin and curcuminoides XLVII.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20120830

• Trapping of methylglyoxal by curcumin in cell-free systems and in human umbilical vein endothelial cells.

  Journal of agricultural and food chemistry 20120822

• Coupling to a cancer cell-specific antibody potentiates tumoricidal properties of curcumin.

  International journal of cancer 20120815

• Chemoprevention of azoxymethane-initiated colon cancer in rat by using a novel polymeric nanocarrier--curcumin.

  European journal of pharmacology 20120815

• Myelopotentiating effect of curcumin in tumor-bearing host: role of bone marrow resident macrophages.

  Toxicology and applied pharmacology 20120815

• One-step synthesis of biodegradable curcumin-derived hydrogels as potential soft tissue fillers after breast cancer surgery.

  Biomacromolecules 20120813

• Curcumin encapsulation in submicrometer spray-dried chitosan/Tween 20 particles.

  Biomacromolecules 20120813

• Invertible micellar polymer assemblies for delivery of poorly water-soluble drugs.

  Biomacromolecules 20120813

• Functional mesoporous silica nanoparticles for photothermal-controlled drug delivery in vivo.

  Angewandte Chemie (International ed. in English) 20120813

• Remarkable photocytotoxicity of curcumin in HeLa cells in visible light and arresting its degradation on oxovanadium(IV) complex formation.

  Chemical communications (Cambridge, England) 20120811

• Potentiation of etoposide and temozolomide cytotoxicity by curcumin and turmeric force™ in brain tumor cell lines.

  Journal of complementary & integrative medicine 20120810

• Inhibition of histone acetylation by curcumin reduces alcohol-induced expression of heart development-related transcription factors in cardiac progenitor cells.

  Biochemical and biophysical research communications 20120803

• Pharmacogenomic determination of genes associated with sensitivity or resistance of tumor cells to curcumin and curcumin derivatives.

  The Journal of nutritional biochemistry 20120801

• Curcumin-supplemented yoghurt improves physiological and biochemical markers of experimental diabetes.

  The British journal of nutrition 20120801

• Induction of oxidative stress and inhibition of superoxide dismutase expression in rat cerebral cortex and cerebellum by PTU-induced hypothyroidism and its reversal by curcumin.

  Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20120801

• N-methyl N-nitrosourea induced functional and structural alterations in mice brain-role of curcumin.

  Neurotoxicity research 20120801

• Ameliorative effects of curcumin against acute cadmium toxicity on male reproductive system in rats.

  Andrologia 20120801

• The association of manganese superoxide dismutase expression in Barrett's esophageal progression with MnTBAP and curcumin oil therapy.

  The Journal of surgical research 20120801

• Protective effect of curcumin, silymarin and N-acetylcysteine on antitubercular drug-induced hepatotoxicity assessed in an in vitro model.

  Human & experimental toxicology 20120801

• Curcumin inhibits gene expression of receptor for advanced glycation end-products (RAGE) in hepatic stellate cells in vitro by elevating PPARγ activity and attenuating oxidative stress.

  British journal of pharmacology 20120801

• Validity of silver, chitosan, and curcumin nanoparticles as anti-Giardia agents.

  Parasitology research 20120801

• Curcumin inhibits LPS-induced CCL2 expression via JNK pathway in C6 rat astrocytoma cells.

  Cellular and molecular neurobiology 20120801

• Curcumin ameliorates hepatic fibrosis in type 2 diabetes mellitus - insights into its mechanisms of action.

  British journal of pharmacology 20120801

• Curcumin inhibits tumor proliferation induced by neutrophil elastase through the upregulation of α1-antitrypsin in lung cancer.

  Molecular oncology 20120801

• Curcumin enhances non-opsonic phagocytosis of Plasmodium falciparum through up-regulation of CD36 surface expression on monocytes/macrophages.

  The Journal of antimicrobial chemotherapy 20120801

• Design and evaluation of cyclodextrin-based delivery systems to incorporate poorly soluble curcumin analogs for the treatment of melanoma.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20120801

• Suppressive effects of a pyrazole derivative of curcumin on airway inflammation and remodeling.

  Experimental and molecular pathology 20120801

• Curcumin-induced autophagy contributes to the decreased survival of oral cancer cells.

  Archives of oral biology 20120801

• Hybrid fluorescent curcumin loaded zein electrospun nanofibrous scaffold for biomedical applications.

  Biomedical materials (Bristol, England) 20120801

• Inhibitory effect of curcumin on the Al(III)-induced Aβ₄₂ aggregation and neurotoxicity in vitro.

  Biochimica et biophysica acta 20120801

• Auto-acetylation stabilizes p300 in cardiac myocytes during acute oxidative stress, promoting STAT3 accumulation and cell survival.

  Breast cancer research and treatment 20120801

• Beneficial effects of curcumin on antitumor activity and adverse reactions of doxorubicin.

  International journal of pharmaceutics 20120801

• Reproductive effects of a pegylated curcumin.

  Reproductive toxicology (Elmsford, N.Y.) 20120801

• The increased cellular uptake and biliary excretion of curcumin by quercetin: a possible role of albumin binding interaction.

  Drug metabolism and disposition: the biological fate of chemicals 20120801

• Sphingosine kinase-1 inhibition sensitizes curcumin-induced growth inhibition and apoptosis in ovarian cancer cells.

  Cancer science 20120801

• Curcumin inhibits tongue carcinoma cells migration and invasion through downregulation of matrix metallopeptidase 10.

  Cancer investigation 20120801

• Curcumin targeting the thioredoxin system elevates oxidative stress in HeLa cells.

  Toxicology and applied pharmacology 20120801

• Curcumin and neurodegenerative diseases: a perspective.

  Expert opinion on investigational drugs 20120801

• Synthesis and evaluation of antimicrobial activity of 4H-pyrimido[2,1-b]benzothiazole, pyrazole and benzylidene derivatives of curcumin.

  European journal of medicinal chemistry 20120801

• Novel curcumin analogue UBS109 potently stimulates osteoblastogenesis and suppresses osteoclastogenesis: involvement in Smad activation and NF-κB inhibition.

  Integrative biology : quantitative biosciences from nano to macro 20120801

• Isolation and identification of phase 1 metabolites of curcuminoids in rats.

  Planta medica 20120801

• Dietary curcumin inhibits atherosclerosis by affecting the expression of genes involved in leukocyte adhesion and transendothelial migration.

  Molecular nutrition & food research 20120801

• Effects of curcumin on nitrosyl-iron complex-mediated DNA cleavage and cytotoxicity.

  Planta medica 20120801

• The influence of curcumin, quercetin, and eicosapentaenoic acid on the expression of phase II detoxification enzymes in the intestinal cell lines HT-29, Caco-2, HuTu 80, and LT97.

  Nutrition and cancer 20120801

• Reduction of DNA damage by curcumin and celecoxib in epithelial cell cultures of the oropharynx after incubation with tobacco smoke condensate.

  Anticancer research 20120801

• In vivo evaluation of curcumin loaded nanosuspensions by oral administration.

  Journal of biomedical nanotechnology 20120801

• Curcumin encapsulated in chitosan nanoparticles: a novel strategy for the treatment of arsenic toxicity.

  Chemico-biological interactions 20120730

• Preparation and enhancement of oral bioavailability of curcumin using microemulsions vehicle.

  Journal of agricultural and food chemistry 20120725

• [Curcumin inhibits iron overload-induced hepatocytic apoptosis and nuclear factor-κB activity].

  Zhonghua yi xue za zhi 20120724

• Curcumin protects against cigarette smoke-induced cognitive impairment and increased acetylcholinesterase activity in rats.

  Physiology & behavior 20120716

• Preliminary experience with personalized and targeted therapy for pediatric brain tumors.

  Pediatric blood & cancer 20120715

• Arachidonic acid stimulates TNFα production in Kupffer cells via a reactive oxygen species-pERK1/2-Egr1-dependent mechanism.

  American journal of physiology. Gastrointestinal and liver physiology 20120715

• β₂-adrenoceptor and insulin receptor expression in the skeletal muscle of streptozotocin induced diabetic rats: antagonism by vitamin D₃ and curcumin.

  European journal of pharmacology 20120715

• Protective effect of curcumin on cypermethrin-induced oxidative stress in Wistar rats.

  Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20120701

• Curcumin suppresses Streptococcus mutans adherence to human tooth surfaces and extracellular matrix proteins.

  European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20120701

• Curcumin attenuates TNF-α-induced expression of intercellular adhesion molecule-1, vascular cell adhesion molecule-1 and proinflammatory cytokines in human endometriotic stromal cells.

  Phytotherapy research : PTR 20120701

• Curcumin potentiates antitumor activity of L-asparaginase via inhibition of the AKT signaling pathway in acute lymphoblastic leukemia.

  Leukemia & lymphoma 20120701

• In vitro biocompatibility of thermally gelling liquid mucoadhesive loaded curcuminoids in colorectal cancer chemoprevention.

  International journal of colorectal disease 20120701

• Oxidative damage is ameliorated by curcumin treatment in brain and sciatic nerve of diabetic rats.

  The International journal of neuroscience 20120701

• Protective role of curcumin on colchicine-induced cognitive dysfunction and oxidative stress in rats.

  Human & experimental toxicology 20120701

• Curcumin improves the antitumor effect of X-ray irradiation by blocking the NF-κB pathway: an in-vitro study of lymphoma.

  Anti-cancer drugs 20120701

• Pharmacokinetic interaction study of sulphasalazine in healthy subjects and the impact of curcumin as an in vivo inhibitor of BCRP.

  British journal of pharmacology 20120701

• Curcumin for the prevention of acute lung injury in sepsis: is it more than the flavor of the month?

  The Journal of surgical research 20120701

• Inclusion complex of novel curcumin analogue CDF and β-cyclodextrin (1:2) and its enhanced in vivo anticancer activity against pancreatic cancer.

  Pharmaceutical research 20120701

• Curcumin ameliorates hydrogen peroxide-induced epithelial barrier disruption by upregulating heme oxygenase-1 expression in human intestinal epithelial cells.

  Digestive diseases and sciences 20120701

• Synthesis and characterization of poly(antioxidant β-amino esters) for controlled release of polyphenolic antioxidants.

  Acta biomaterialia 20120701

• HSP27 modulates survival signaling networks in cells treated with curcumin and TRAIL.

  Cellular signalling 20120701

• Protective effects of curcumin on amyloid-β-induced neuronal oxidative damage.

  Neurochemical research 20120701

• Effects of curcuminoids on frequency of acute myocardial infarction after coronary artery bypass grafting.

  The American journal of cardiology 20120701

• Antiglioma activity of curcumin-loaded lipid nanoparticles and its enhanced bioavailability in brain tissue for effective glioblastoma therapy.

  Acta biomaterialia 20120701

• Curcumin protects against sepsis-induced acute lung injury in rats.

  The Journal of surgical research 20120701

• A dual role for poly(ADP-ribose) polymerase-1 during caspase-dependent apoptosis.

  Toxicological sciences : an official journal of the Society of Toxicology 20120701

• Rheological characterization of a xanthan-galactomannan hydrogel loaded with lipophilic substances.

  Journal of pharmaceutical sciences 20120701

• Synthesis and evaluation of curcumin-related compounds for anticancer activity.

  European journal of medicinal chemistry 20120701

• Demethoxycurcumin inhibits cell proliferation, migration and invasion in prostate cancer cells.

  Oncology reports 20120701

• Comparison of the effect of p65 siRNA and curcumin in promoting apoptosis in esophageal squamous cell carcinoma cells and in nude mice.

  Oncology reports 20120701

• Curcuminoids-loaded liposomes in combination with arteether protects against Plasmodium berghei infection in mice.

  Experimental parasitology 20120701

• Involvement of NF-κB activation in the cisplatin resistance of human epidermoid carcinoma KCP-4 cells.

  Oncology reports 20120701

• Vanillin and ferulic acid: not the major degradation products of curcumin.

  Trends in molecular medicine 20120701

• Antitumor agents 290. Design, synthesis, and biological evaluation of new LNCaP and PC-3 cytotoxic curcumin analogs conjugated with anti-androgens.

  Bioorganic & medicinal chemistry 20120701

• A liquid chromatography-tandem mass spectrometric method for quantification of curcumin-O-glucuronide and curcumin in human plasma.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120701

• Photodynamic effects of curcumin against cariogenic pathogens.

  Photomedicine and laser surgery 20120701

• Cancer stem cells: potential target for bioactive food components.

  The Journal of nutritional biochemistry 20120701

• Death by design: where curcumin sensitizes drug-resistant tumours.

  Anticancer research 20120701

• Rottlerin and curcumin: a comparative analysis.

  Annals of the New York Academy of Sciences 20120701

• Curcumin induces differentiation of embryonic stem cells through possible modulation of nitric oxide-cyclic GMP pathway.

  Protein & cell 20120701

• Advances in nanotechnology-based delivery systems for curcumin.

  Nanomedicine (London, England) 20120701

• Inhibitory effect of hexahydrocurcumin on human platelet aggregation.

  Natural product communications 20120701

• Effects of sulforophane and curcumin on oxidative stress created by acute malathion toxicity in rats.

  European review for medical and pharmacological sciences 20120701

• Transcriptome modification of white blood cells after dietary administration of curcumin and non-steroidal anti-inflammatory drug in osteoarthritic affected dogs.

  Veterinary immunology and immunopathology 20120630

• In-line cold column trapping of organic phase in dispersive liquid-liquid microextraction: enrichment and determination of curcumin in human serum.

  Journal of chromatography. A 20120629

• RETRACTED: Increased Ras GTPase activity is regulated by miRNAs that can be attenuated by CDF treatment in pancreatic cancer cells.

  Cancer letters 20120628

• The effect of curcumin on the stability of Aβ dimers.

  The journal of physical chemistry. B 20120628

• Curcumin reverses cis-platin resistance and promotes human lung adenocarcinoma A549/DDP cell apoptosis through HIF-1α and caspase-3 mechanisms.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20120615

• Curcumin modulates the self-assembly of the islet amyloid polypeptide by disassembling α-helix.

  Biochemical and biophysical research communications 20120615

• Prevention of iron- and copper-mediated DNA damage by catecholamine and amino acid neurotransmitters, L-DOPA, and curcumin: metal binding as a general antioxidant mechanism.

  Dalton transactions (Cambridge, England : 2003) 20120607

• Protein dependent fate of hepatic cells under nicotine induced stress and curcumin ameliorated condition.

  European journal of pharmacology 20120605

• Small molecules, LLL12 and FLLL32, inhibit STAT3 and exhibit potent growth suppressive activity in osteosarcoma cells and tumor growth in mice.

  Investigational new drugs 20120601

• The curry spice curcumin selectively inhibits cancer cells growth in vitro and in preclinical model of glioblastoma.

  The Journal of nutritional biochemistry 20120601

• In vitro and in situ evaluation of herb-drug interactions during intestinal metabolism and absorption of baicalein.

  Journal of ethnopharmacology 20120601

• ICAM-1 and IL-8 are expressed by DEHP and suppressed by curcumin through ERK and p38 MAPK in human umbilical vein endothelial cells.

  Inflammation 20120601

• N-trimethyl chitosan chloride-coated liposomes for the oral delivery of curcumin.

  Journal of liposome research 20120601

• Exploration of the binding of curcumin analogues to human P450 2C9 based on docking and molecular dynamics simulation.

  Journal of molecular modeling 20120601

• Curcumin treatment provides protection against Trypanosoma cruzi infection.

  Parasitology research 20120601

• Inhibition of high glucose-induced inflammatory response and macrophage infiltration by a novel curcumin derivative prevents renal injury in diabetic rats.

  British journal of pharmacology 20120601

• A novel voltammetric sensor for amoxicillin based on nickel-curcumin complex modified carbon paste electrode.

  Bioelectrochemistry (Amsterdam, Netherlands) 20120601

• Preventive effect of caffeine and curcumin on hepato-carcinogenesis in diethylnitrosamine-induced rats.

  International journal of oncology 20120601

• Curcumin causes promoter hypomethylation and increased expression of FANCF gene in SiHa cell line.

  Molecular and cellular biochemistry 20120601

• Acupuncture combined with curcumin attenuates carbon tetrachloride-induced hepatic fibrosis in rats.

  Acupuncture in medicine : journal of the British Medical Acupuncture Society 20120601

• Preparation and in vitro evaluation of a folate-linked liposomal curcumin formulation.

  Journal of liposome research 20120601

• Study on effect of lipophilic curcumin on sub-domain IIA site of human serum albumin during unfolded and refolded states: a synchronous fluorescence spectroscopic study.

  Colloids and surfaces. B, Biointerfaces 20120601

• Curcumin has neuroprotection effect on homocysteine rat model of Parkinson.

  Journal of molecular neuroscience : MN 20120601

• Effect of endurance exercise training and curcumin intake on central arterial hemodynamics in postmenopausal women: pilot study.

  American journal of hypertension 20120601

• Curcumin eliminates the inhibitory effect of advanced glycation end-products (AGEs) on gene expression of AGE receptor-1 in hepatic stellate cells in vitro.

  Laboratory investigation; a journal of technical methods and pathology 20120601

• The effect of the NF-kappa B inhibitors curcumin and lactacystin on myogenic differentiation of rhabdomyosarcoma cells.

  Differentiation; research in biological diversity 20120601

• Synergistic anticancer activity of curcumin and bleomycin: an in vitro study using human malignant testicular germ cells.

  Molecular medicine reports 20120601

• Identification of differentially expressed proteins in curcumin-treated prostate cancer cell lines.

  Omics : a journal of integrative biology 20120601

• Curcumin induces apoptosis in tumor necrosis factor-alpha-treated HaCaT cells.

  International immunopharmacology 20120601

• Curcumin loaded NLC induces histone hypoacetylation in the CNS after intraperitoneal administration in mice.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20120601

• Curcumin inhibits proliferation and invasion of osteosarcoma cells through inactivation of Notch-1 signaling.

  The FEBS journal 20120601

• Curcumin induces cell apoptosis in human chondrosarcoma through extrinsic death receptor pathway.

  International immunopharmacology 20120601

• Synthetic curcumin analog EF31 inhibits the growth of head and neck squamous cell carcinoma xenografts.

  Integrative biology : quantitative biosciences from nano to macro 20120601

• Evaluation of the antiepileptic effect of curcumin and Nigella sativa oil in the pilocarpine model of epilepsy in comparison with valproate.

  Epilepsy & behavior : E&B 20120601

• Enhancement of cellular uptake and cytotoxicity of curcumin-loaded PLGA nanoparticles by conjugation with anti-P-glycoprotein in drug resistance cancer cells.

  Acta pharmacologica Sinica 20120601

• Curcumin induces permanent growth arrest of human colon cancer cells: link between senescence and autophagy.

  Mechanisms of ageing and development 20120601

• Natural polyphenols as modulators of TTR amyloidogenesis: in vitro and in vivo evidences towards therapy.

  Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 20120601

• Curcumin protects nigral dopaminergic neurons by iron-chelation in the 6-hydroxydopamine rat model of Parkinson's disease.

  Neuroscience bulletin 20120601

• Interaction between curcumin and mimetic biomembrane.

  Science China. Life sciences 20120601

• [Adsorption dynamics study on interactions of pigments and human whole saliva].

  Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology 20120601

• A composite polymer nanoparticle overcomes multidrug resistance and ameliorates doxorubicin-associated cardiomyopathy.

  Oncotarget 20120601

• Physiological barriers to the oral delivery of curcumin.

  Die Pharmazie 20120601

• Chitosan microparticles for oral bioavailability improvement of the hydrophobic drug curcumin.

  Die Pharmazie 20120601

• Anticonvulsive and antioxidant effects of curcumin on pilocarpine-induced seizures in rats.

  Chinese medical journal 20120601

• Improving the oral bioavailability of curcumin using novel organogel-based nanoemulsions.

  Journal of agricultural and food chemistry 20120530

• Antioxidant activities of curcumin and ascorbyl dipalmitate nanoparticles and their activities after incorporation into cellulose-based packaging films.

  Journal of agricultural and food chemistry 20120530

• Curcumin--from molecule to biological function.

  Angewandte Chemie (International ed. in English) 20120529

• Hexahydrocurcumin enhances inhibitory effect of 5-fluorouracil on HT-29 human colon cancer cells.

  World journal of gastroenterology 20120521

• Preparation of curcumin-loaded liposomes and evaluation of their skin permeation and pharmacodynamics.

  Molecules (Basel, Switzerland) 20120518

• The release rate of curcumin from calcium alginate beads regulated by food emulsifiers.

  Journal of agricultural and food chemistry 20120502

• The preventative role of curcumin on the lung inflammatory response induced by cardiopulmonary bypass in rats.

  The Journal of surgical research 20120501

• Effects of curcumin and dithioerythritol on frozen-thawed bovine semen.

  Andrologia 20120501

• Amelioration of renal ischaemia-reperfusion injury by liposomal delivery of curcumin to renal tubular epithelial and antigen-presenting cells.

  British journal of pharmacology 20120501

• The curcumin analog ca27 down-regulates androgen receptor through an oxidative stress mediated mechanism in human prostate cancer cells.

  The Prostate 20120501

• Curcumin-loaded γ-cyclodextrin liposomal nanoparticles as delivery vehicles for osteosarcoma.

  Nanomedicine : nanotechnology, biology, and medicine 20120501

• High-dose curcuminoids are efficacious in the reduction in symptoms and signs of oral lichen planus.

  Journal of the American Academy of Dermatology 20120501

• Piperine as an adjuvant increases the efficacy of curcumin in mitigating benzo(a)pyrene toxicity.

  Human & experimental toxicology 20120501

• Curcumin protects nigrostriatal dopaminergic neurons and reduces glial activation in 6-hydroxydopamine hemiparkinsonian mice model.

  The International journal of neuroscience 20120501

• Effects of oxidative stress caused by tert-butylhydroquinone on cytotoxicity in MDCK cells.

  The Journal of veterinary medical science 20120501

• Tetrahydrocurcumin ameliorates homocysteinylated cytochrome-c mediated autophagy in hyperhomocysteinemia mice after cerebral ischemia.

  Journal of molecular neuroscience : MN 20120501

• Genotoxic stress and activation of novel DNA repair enzymes in human endothelial cells and in the retinas and kidneys of streptozotocin diabetic rats.

  Diabetes/metabolism research and reviews 20120501

• Barrier protective activities of curcumin and its derivative.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20120501

• Expression analysis of Cdc42 in lung cancer and modulation of its expression by curcumin in lung cancer cell lines.

  International journal of oncology 20120501

• Liposome-encapsulated curcumin suppresses neuroblastoma growth through nuclear factor-kappa B inhibition.

  Surgery 20120501

• The CB₁ receptor-mediated endocannabinoid signaling and NGF: the novel targets of curcumin.

  Neurochemical research 20120501

• Time-resolved fluorescence study during denaturation and renaturation of curcumin-myoglobin complex.

  International journal of biological macromolecules 20120501

• Glutathione regulates caspase-dependent ceramide production and curcumin-induced apoptosis in human leukemic cells.

  Free radical biology & medicine 20120501

• Hydrocolloid-based nutraceutical delivery systems.

  Food & function 20120501

• Effect of curcumin in a mouse model of Pelizaeus-Merzbacher disease.

  Molecular genetics and metabolism 20120501

• The chemopreventive and clinically used agent curcumin sensitizes HPV (-) but not HPV (+) HNSCC to ionizing radiation, in vitro and in a mouse orthotopic model.

  Cancer biology & therapy 20120501

• The effects of curcumin post-treatment against myocardial ischemia and reperfusion by activation of the JAK2/STAT3 signaling pathway.

  Basic research in cardiology 20120501

• Monoclonal gammopathy of undetermined significance, smoldering multiple myeloma, and curcumin: a randomized, double-blind placebo-controlled cross-over 4g study and an open-label 8g extension study.

  American journal of hematology 20120501

• Preventive strategies in monoclonal gammopathy of undetermined significance and smoldering multiple myeloma.

  American journal of hematology 20120501

• Effect of curcumin on miRNA expression in human Y79 retinoblastoma cells.

  Current eye research 20120501

• Curcumin inhibits proliferation of human lens epithelial cells: a proteomic analysis.

  Journal of Zhejiang University. Science. B 20120501

• [Protective effect and mechanism of curcumin on ActD/TNF-α-induced synergistically apoptosis in PC12 cells].

  Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20120501

• Premature mitochondrial senescence and related ultrastructural changes during lung carcinogenesis modulation by curcumin and resveratrol.

  Ultrastructural pathology 20120501

• The protective effect of curcumin on ischemia-reperfusion-induced liver injury.

  Transplantation proceedings 20120501

• [Effects of curcumin on syndecan-4 protein and p44/42 mitogen-activated protein kinase expression in tumor necrosis factor-α-induced rat vascular smooth muscle cells in vitro].

  Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20120501

• Aggregation and inactivation of pancreatic cystatin by riboflavin-derived singlet oxygen and flavin triplet state: polyphenols as preventive agents.

  Journal of biochemical and molecular toxicology 20120501

• Curcumin induces autophagy to protect vascular endothelial cell survival from oxidative stress damage.

  Autophagy 20120501

• Molecular mechanism of curcumin on the suppression of cholesterol accumulation in macrophage foam cells and atherosclerosis.

  Molecular nutrition & food research 20120501

• A particular expression pattern of CD13 epitope 7H5 in chronic lymphocytic leukaemia--a possible new therapeutic target.

  Hematology (Amsterdam, Netherlands) 20120501

• [Experimental study of signal transduction mechanism of curcumin protective effects on radiation-induced vascular endothelial injuries].

  Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20120501

• [Study on curcumin-induced apoptosis in ovarian cancer resistant cell lines COC1/DDP].

  Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20120501

• [Anti-tumor effect of tanshinone II A, tetrandrine, honokiol, curcumin, oridonin and paeonol on leukemia cell lines].

  Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20120501

• Study of curcumin on microvasculature characteristic in diabetic rat's liver as revealed by vascular corrosion cast/scanning electron microscope (SEM) technique.

  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20120501

• Microfluidic fabrication of cationic curcumin nanoparticles as an anti-cancer agent.

  Nanoscale 20120421

• Green amorphous nanoplex as a new supersaturating drug delivery system.

  Langmuir : the ACS journal of surfaces and colloids 20120417

• Reversion of multidrug resistance by co-encapsulation of doxorubicin and curcumin in chitosan/poly(butyl cyanoacrylate) nanoparticles.

  International journal of pharmaceutics 20120415

• Design, synthesis, synergistic antimicrobial activity and cytotoxicity of 4-aryl substituted 3,4-dihydropyrimidinones of curcumin.

  Bioorganic & medicinal chemistry letters 20120415

• Curcumin prevents chronic alcohol-induced liver disease involving decreasing ROS generation and enhancing antioxidative capacity.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20120415

• Novel role of Zn(II)-curcumin in enhancing cell proliferation and adjusting proinflammatory cytokine-mediated oxidative damage of ethanol-induced acute gastric ulcers.

  Chemico-biological interactions 20120415

• Design and self-assembly of a leucine-enkephalin analogue in different nanostructures: application of nanovesicles.

  Small (Weinheim an der Bergstrasse, Germany) 20120410

• Curcumin prevents indomethacin-induced gastropathy in rats.

  World journal of gastroenterology 20120407

• Purely aqueous PLGA nanoparticulate formulations of curcumin exhibit enhanced anticancer activity with dependence on the combination of the carrier.

  International journal of pharmaceutics 20120404

• Curcumin bioavailability from enriched bread: the effect of microencapsulated ingredients.

  Journal of agricultural and food chemistry 20120404

• The curcuminoid CLEFMA selectively induces cell death in H441 lung adenocarcinoma cells via oxidative stress.

  Investigational new drugs 20120401

• In vivo protective effect of dietary curcumin in fish Anabas testudineus (Bloch).

  Fish physiology and biochemistry 20120401

• A novel synthetic mono-carbonyl analogue of curcumin, A13, exhibits anti-inflammatory effects in vivo by inhibition of inflammatory mediators.

  Inflammation 20120401

• Synthesis and antioxidant, cytotoxicity and antimicrobial activities of novel curcumin mimics.

  Journal of enzyme inhibition and medicinal chemistry 20120401

• A Lipo-PEG-PEI complex for encapsulating curcumin that enhances its antitumor effects on curcumin-sensitive and curcumin-resistance cells.

  Nanomedicine : nanotechnology, biology, and medicine 20120401

• Role of curcumin on chloroquine phosphate-induced reproductive toxicity.

  Drug and chemical toxicology 20120401

• Anti-carcinogenic action of curcumin by activation of antioxidant defence system and inhibition of NF-κB signalling in lymphoma-bearing mice.

  Bioscience reports 20120401

• Curcumin inhibits metastatic progression of breast cancer cell through suppression of urokinase-type plasminogen activator by NF-kappa B signaling pathways.

  Molecular biology reports 20120401

• Curcuminoid analogs inhibit nitric oxide production from LPS-activated microglial cells.

  Journal of natural medicines 20120401

• Tetrahydrocurcumin alleviates hypertension, aortic stiffening and oxidative stress in rats with nitric oxide deficiency.

  Hypertension research : official journal of the Japanese Society of Hypertension 20120401

• The binding of curcumin to various types of canine amyloid proteins.

  The Journal of veterinary medical science 20120401

• Dimethoxycurcumin-induced cell death in human breast carcinoma MCF7 cells: evidence for pro-oxidant activity, mitochondrial dysfunction, and apoptosis.

  Archives of toxicology 20120401

• In vitro vs. in vivo tape stripping: validation of the porcine ear model and penetration assessment of novel sucrose stearate emulsions.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20120401

• Artemisinin and artemisinin plus curcumin liposomal formulations: enhanced antimalarial efficacy against Plasmodium berghei-infected mice.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20120401

• Anticandidal activity of curcumin and methyl cinnamaldehyde.

  Fitoterapia 20120401

• The curcumin analogue hydrazinocurcumin exhibits potent suppressive activity on carcinogenicity of breast cancer cells via STAT3 inhibition.

  International journal of oncology 20120401

• Curcumin promotes differentiation of glioma-initiating cells by inducing autophagy.

  Cancer science 20120401

• Tissue localization of nanoparticles is altered due to hypoxia resulting in poor efficacy of curcumin nanoparticles in pulmonary hypertension.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20120401

• Controlled systemic delivery by polymeric implants enhances tissue and plasma curcumin levels compared with oral administration.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20120401

• Impact of curcumin supersaturation in antibacterial photodynamic therapy--effect of cyclodextrin type and amount: studies on curcumin and curcuminoides XLV.

  Journal of pharmaceutical sciences 20120401

• Cytotoxic, cytoprotective and antioxidant effects of isolated phenolic compounds from fresh ginger.

  Fitoterapia 20120401

• Curcumin inhibits protein phosphatases 2A and 5, leading to activation of mitogen-activated protein kinases and death in tumor cells.

  Carcinogenesis 20120401

• Shotgun proteomics and network analysis of neuroblastoma cell lines treated with curcumin.

  Molecular bioSystems 20120401

• Protective effects of combined therapy of gliclazide with curcumin in experimental diabetic neuropathy in rats.

  Behavioural pharmacology 20120401

• Curcumin abrogates bile-induced NF-κB activity and DNA damage in vitro and suppresses NF-κB activity whilst promoting apoptosis in vivo, suggesting chemopreventative potential in Barrett's oesophagus.

  Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20120401

• Trolox enhances curcumin's cytotoxicity through induction of oxidative stress.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120401

• Anticoagulant activities of curcumin and its derivative.

  BMB reports 20120401

• Formation of tetrahydrocurcumin by reduction of curcumin with cultured plant cells of Marchantia polymorpha.

  Natural product communications 20120401

• The effect of coenzyme Q10 and curcumin on chronic methanol intoxication induced retinopathy in rats.

  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20120401

• The protective effect of curcumin on Aβ induced aberrant cell cycle reentry on primary cultured rat cortical neurons.

  European review for medical and pharmacological sciences 20120401

• The protective effects of curcumin on intestine and remote organs against mesenteric ischemia/reperfusion injury.

  The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology 20120401

• Curcumin suppresses T cell activation by blocking Ca2+ mobilization and nuclear factor of activated T cells (NFAT) activation.

  The Journal of biological chemistry 20120323

• Nrf2-dependent induction of proteasome and Pa28αβ regulator are required for adaptation to oxidative stress.

  The Journal of biological chemistry 20120323

• Curcumin prevents aggregation in α-synuclein by increasing reconfiguration rate.

  The Journal of biological chemistry 20120316

• Preparation and pharmacokinetic evaluation of curcumin solid dispersion using Solutol® HS15 as a carrier.

  International journal of pharmaceutics 20120315

• Curcumin as anti-endometriotic agent: implication of MMP-3 and intrinsic apoptotic pathway.

  Biochemical pharmacology 20120315

• Elaboration of chitosan-coated nanoparticles loaded with curcumin for mucoadhesive applications.

  Journal of colloid and interface science 20120315

• An understanding of the modulation of photophysical properties of curcumin inside a micelle formed by an ionic liquid: a new possibility of tunable drug delivery system.

  The journal of physical chemistry. B 20120315

• Nanoparticles synthesized from soy protein: preparation, characterization, and application for nutraceutical encapsulation.

  Journal of agricultural and food chemistry 20120314

• The effect of a mild base on curcumin in methanol and ethanol.

  The journal of physical chemistry. A 20120308

• Therapeutic role of curcumin in prevention of biochemical and behavioral aberration induced by alcoholic neuropathy in laboratory animals.

  Neuroscience letters 20120305

• Protective role of curcumin in nephrotoxic oxidative damage induced by vancomycin in rats.

  Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20120301

• Curcumin treatment prevents increased proteasome and apoptosome activities in rat skeletal muscle during reloading and improves subsequent recovery.

  The Journal of nutritional biochemistry 20120301

• Anti-apoptotic effects of curcumin on cadmium-induced apoptosis in rat testes.

  Toxicology and industrial health 20120301

• Food additives such as sodium sulphite, sodium benzoate and curcumin inhibit leptin release in lipopolysaccharide-treated murine adipocytes in vitro.

  The British journal of nutrition 20120301

• Physical characterization and cellular uptake of propylene glycol liposomes in vitro.

  Drug development and industrial pharmacy 20120301

• Protective effects of curcumin against sodium fluoride-induced toxicity in rat kidneys.

  Biological trace element research 20120301

• Antinociceptive activity of a synthetic curcuminoid analogue, 2,6-bis-(4-hydroxy-3-methoxybenzylidene)cyclohexanone, on nociception-induced models in mice.

  Basic & clinical pharmacology & toxicology 20120301

• Enhancement of curcumin oral absorption and pharmacokinetics of curcuminoids and curcumin metabolites in mice.

  Cancer chemotherapy and pharmacology 20120301

• Enhancement of mitomycin C-induced cytotoxicity by curcumin results from down-regulation of MKK1/2-ERK1/2-mediated thymidine phosphorylase expression.

  Basic & clinical pharmacology & toxicology 20120301

• Protective effects of curcumin, α-lipoic acid, and N-acetylcysteine against carbon tetrachloride-induced liver fibrosis in rats.

  Journal of physiology and biochemistry 20120301

• Regulatory effects of curcumin on lipid accumulation in monocytes/macrophages.

  Journal of cellular biochemistry 20120301

• Studies on curcumin and curcuminoids. XLVI. Photophysical properties of dimethoxycurcumin and bis-dehydroxycurcumin.

  Journal of fluorescence 20120301

• Curcumin and its formulations: potential anti-cancer agents.

  Anti-cancer agents in medicinal chemistry 20120301

• Curcumin alleviates eosinophilic meningitis through reduction of eosinophil count following albendazole treatment against Angiostrongylus cantonensis in mice.

  Parasitology 20120301

• Discovery of curcumin, a component of golden spice, and its miraculous biological activities.

  Clinical and experimental pharmacology & physiology 20120301

• Stress proteins and glial cell functions during chronic aluminium exposures: protective role of curcumin.

  Neurochemical research 20120301

• Immunomodulation of curcumin on adoptive therapy with T cell functional imaging in mice.

  Cancer prevention research (Philadelphia, Pa.) 20120301

• Cytoprotective effects of curcumin on sodium fluoride-induced intoxication in rat erythrocytes.

  Bulletin of environmental contamination and toxicology 20120301

• A novel mono-carbonyl analogue of curcumin induces apoptosis in ovarian carcinoma cells via endoplasmic reticulum stress and reactive oxygen species production.

  Molecular medicine reports 20120301

• Improved bioavailability of poorly water-soluble drug curcumin in cellulose acetate solid dispersion.

  AAPS PharmSciTech 20120301

• The role of turmerones on curcumin transportation and P-glycoprotein activities in intestinal Caco-2 cells.

  Journal of medicinal food 20120301

• Lack of efficacy of curcumin on neurodegeneration in the mouse model of Niemann-Pick C1.

  Pharmacology, biochemistry, and behavior 20120301

• Effects of curcumin and related compounds on processes involving α-hydroxyethyl radicals.

  Free radical research 20120301

• Targeting pioneering factor and hormone receptor cooperative pathways to suppress tumor progression.

  Cancer research 20120301

• Nicotine stimulates urokinase-type plasminogen activator receptor expression and cell invasiveness through mitogen-activated protein kinase and reactive oxygen species signaling in ECV304 endothelial cells.

  Toxicology and applied pharmacology 20120301

• Natural products as anti-glycation agents: possible therapeutic potential for diabetic complications.

  Current diabetes reviews 20120301

• Quantitative determination of proteins based on strong fluorescence enhancement in curcumin-chitosan-proteins system.

  Journal of fluorescence 20120301

• Nickel oxide nanoparticles induce cytotoxicity, oxidative stress and apoptosis in cultured human cells that is abrogated by the dietary antioxidant curcumin.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120301

• Polycystic kidney disease: a 2011 update.

  Current opinion in nephrology and hypertension 20120301

• Effects of diarylpentanoid analogues of curcumin on chemiluminescence and chemotactic activities of phagocytes.

  The Journal of pharmacy and pharmacology 20120301

• Curcumin protects against the oxidative damage induced by the pesticide parathion in the hippocampus of the rat brain.

  Nutritional neuroscience 20120301

• The pharmacology of curcumin: is it the degradation products?

  Trends in molecular medicine 20120301

• Characterization of photovoltaic performance of the dye-sensitized solar cell with a novel ruthenium complex having a bisdemethoxycurcumin as a ligand.

  Ambio 20120301

• Mosquitocidal properties of natural product compounds isolated from Chinese herbs and synthetic analogs of curcumin.

  Journal of medical entomology 20120301

• Evaluating cell migration in vitro by the method based on cell patterning within microfluidic channels.

  Electrophoresis 20120301

• Protective efficacy of 2-PAMCl, atropine and curcumin against dichlorvos induced toxicity in rats.

  Interdisciplinary toxicology 20120301

• Physicochemical characterization of curcuminoid-loaded solid lipid nanoparticles.

  International journal of pharmaceutics 20120227

• Efficient synthesis of multicyclic spirooxindoles via a cascade Michael/Michael/oxa-Michael reaction of curcumins and isatylidene malononitriles.

  Organic & biomolecular chemistry 20120227

• Curcumin affects cell survival and cell volume regulation in human renal and intestinal cells.

  Toxicology 20120226

• Effects of curcumin concentration and temperature on the spectroscopic properties of liposomal curcumin.

  Journal of agricultural and food chemistry 20120222

• Curcumin heals indomethacin-induced gastric ulceration by stimulation of angiogenesis and restitution of collagen fibers via VEGF and MMP-2 mediated signaling.

  Antioxidants & redox signaling 20120215

• Curcumin and enalapril ameliorate renal failure by antagonizing inflammation in 5/6 nephrectomized rats: role of phospholipase and cyclooxygenase.

  American journal of physiology. Renal physiology 20120215

• Co-delivery of antigen and a lipophilic anti-inflammatory drug to cells via a tailorable nanocarrier emulsion.

  Journal of colloid and interface science 20120215

• Gold nanoparticles generated and stabilized by water soluble curcumin-polymer conjugate: blood compatibility evaluation and targeted drug delivery onto cancer cells.

  Journal of colloid and interface science 20120215

• Synthesis of the pyridinyl analogues of dibenzylideneacetone (pyr-dba) via an improved Claisen-Schmidt condensation, displaying diverse biological activities as curcumin analogues.

  Organic & biomolecular chemistry 20120214

• Antioxidants, like coenzyme Q10, selenite, and curcumin, inhibited osteoclast differentiation by suppressing reactive oxygen species generation.

  Biochemical and biophysical research communications 20120210

• Ruthenium-arene complexes of curcumin: X-ray and density functional theory structure, synthesis, and spectroscopic characterization, in vitro antitumor activity, and DNA docking studies of (p-cymene)Ru(curcuminato)chloro.

  Journal of medicinal chemistry 20120209

• Controlled release pulmonary administration of curcumin using swellable biocompatible microparticles.

  Molecular pharmaceutics 20120206

• Nanocapsulated curcumin: oral chemopreventive formulation against diethylnitrosamine induced hepatocellular carcinoma in rat.

  Chemico-biological interactions 20120205

• Curcumin modulates the immune response associated with LPS-induced periodontal disease in rats.

  Innate immunity 20120201

• Short- and long-term exposure of articular cartilage to curcumin or quercetin inhibits aggrecan loss.

  The Journal of nutritional biochemistry 20120201

• Curcumin inhibits melanogenesis in human melanocytes.

  Phytotherapy research : PTR 20120201

• Expression of antioxidant genes in renal cortex of PTU-induced hypothyroid rats: effect of vitamin E and curcumin.

  Molecular biology reports 20120201

• Curcumin induces small cell lung cancer NCI-H446 cell apoptosis via the reactive oxygen species-mediated mitochondrial pathway and not the cell death receptor pathway.

  DNA and cell biology 20120201

• Curcumin-loaded into PLGA nanoparticles: preparation and in vitro schistosomicidal activity.

  Parasitology research 20120201

• Synergistic anticancer activity of curcumin and catechin: an in vitro study using human cancer cell lines.

  Microscopy research and technique 20120201

• Acceleration of wound repair by curcumin in the excision wound of mice exposed to different doses of fractionated γ radiation.

  International wound journal 20120201

• Suppression of RANKL-dependent heme oxygenase-1 is required for high mobility group box 1 release and osteoclastogenesis.

  Journal of cellular biochemistry 20120201

• Curcumin exerts antinociceptive effects in a mouse model of neuropathic pain: descending monoamine system and opioid receptors are differentially involved.

  Neuropharmacology 20120201

• 1-phenyl-2-decanoylamino-3-morpholino-1-propanol (PDMP) facilitates curcumin-induced melanoma cell apoptosis by enhancing ceramide accumulation, JNK activation, and inhibiting PI3K/AKT activation.

  Molecular and cellular biochemistry 20120201

• Liposomal delivery system enhances anti-inflammatory properties of curcumin.

  Journal of pharmaceutical sciences 20120201

• Effect of curcumin on irradiated and estrogen-transformed human breast cell lines.

  International journal of oncology 20120201

• Curcumin induces the differentiation of myeloid-derived suppressor cells and inhibits their interaction with cancer cells and related tumor growth.

  Cancer prevention research (Philadelphia, Pa.) 20120201

• Natural polyphenols may ameliorate damage induced by copper overload.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120201

• Transferrin-conjugated curcumin-loaded superparamagnetic iron oxide nanoparticles induce augmented cellular uptake and apoptosis in K562 cells.

  Acta biomaterialia 20120201

• Effect on pro-inflammatory and antioxidant genes and bioavailable distribution of whole turmeric vs curcumin: Similar root but different effects.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120201

• Catecholamine-induced cardiac mitochondrial dysfunction and mPTP opening: protective effect of curcumin.

  American journal of physiology. Heart and circulatory physiology 20120201

• Synergistic antitumor efficiency of docetaxel and curcumin against lung cancer.

  Acta biochimica et biophysica Sinica 20120201

• Synthesis and anti-inflammatory properties of some aromatic and heterocyclic aromatic curcuminoids.

  Bioorganic chemistry 20120201

• Curcumin down-regulates visfatin expression and inhibits breast cancer cell invasion.

  Endocrinology 20120201

• Suppression of free fatty acid-induced insulin resistance by phytopolyphenols in C2C12 mouse skeletal muscle cells.

  Journal of agricultural and food chemistry 20120201

• Inhibition of the NF-κB signaling pathway by the curcumin analog, 3,5-Bis(2-pyridinylmethylidene)-4-piperidone (EF31): anti-inflammatory and anti-cancer properties.

  International immunopharmacology 20120201

• Overall-mouth disinfection by photodynamic therapy using curcumin.

  Photomedicine and laser surgery 20120201

• Curcumin exposure modulates multiple pro-apoptotic and anti-apoptotic signaling pathways to antagonize acetaminophen-induced toxicity.

  Current neurovascular research 20120201

• Quantitative structure-retention relationship of curcumin and its analogues.

  Journal of separation science 20120201

• Curcumin molecular targets in obesity and obesity-related cancers.

  Future oncology (London, England) 20120201

• Contribution of formulation and excipients towards enhanced permeation of curcumin.

  Arzneimittel-Forschung 20120201

• Effects of curcumin on the pharmacokinetics of tamoxifen and its active metabolite, 4-hydroxytamoxifen, in rats: possible role of CYP3A4 and P-glycoprotein inhibition by curcumin.

  Die Pharmazie 20120201

• Influence of cosolvents, ionic strength and the method of sample preparation on the solubilization of curcumin by Pluronics and HP-gamma-cyclodextrin. Studies of curcumin and curcuminoids, XLIV.

  Die Pharmazie 20120201

• [Reversing effects of curcumin on multi-drug resistance of Bel7402/5-fu cell line].

  Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20120201

• Curcumin increases vasodilatory effect of cilostazol in diabetic rat aorta.

  Indian journal of experimental biology 20120201

• Curcumin inhibits hERG potassium channels in vitro.

  Toxicology letters 20120125

• Crystal structure, fluorescence, and nanostructuration studies of the first Zn(II) anthracene-based curcuminoid.

  Inorganic chemistry 20120116

• Synthesis, biological evaluation and molecular docking studies of resveratrol derivatives possessing curcumin moiety as potent antitubulin agents.

  Bioorganic & medicinal chemistry 20120115

• Synthesis of substituted benzimidazolyl curcumin mimics and their anticancer activity.

  Bioorganic & medicinal chemistry letters 20120115

• Suppression of esophageal cancer cell growth using curcumin, (-)-epigallocatechin-3-gallate and lovastatin.

  World journal of gastroenterology 20120114

• Evaluation in vitro of synthetic curcumins as agents promoting monocytic gene expression related to β-amyloid clearance.

  Chemical research in toxicology 20120113

• Curcuminoids promote neurite outgrowth in PC12 cells through MAPK/ERK- and PKC-dependent pathways.

  Journal of agricultural and food chemistry 20120111

• Curcumin loaded chitin nanogels for skin cancer treatment via the transdermal route.

  Nanoscale 20120107

• Curcumin regulates airway epithelial cell cytokine responses to the pollutant cadmium.

  Biochemical and biophysical research communications 20120106

• Effect of preparation techniques on the properties of curcumin liposomes: characterization of size, release and cytotoxicity on a squamous oral carcinoma cell line.

  Pharmaceutical development and technology 20120101

• Curcumin and liver cancer: a review.

  Current pharmaceutical biotechnology 20120101

• Natural products of dietary origin as lead compounds in virtual screening and drug design.

  Current pharmaceutical biotechnology 20120101

• Curcumin acts synergistically with fluconazole to sensitize a clinical isolate of Candida albicans showing a MDR phenotype.

  Medical mycology 20120101

• Combined treatment of curcumin and small molecule inhibitors suppresses proliferation of A549 and H1299 human non-small-cell lung cancer cells.

  Phytotherapy research : PTR 20120101

• Dose-escalation and pharmacokinetic study of nanoparticle curcumin, a potential anticancer agent with improved bioavailability, in healthy human volunteers.

  Cancer chemotherapy and pharmacology 20120101

• Fluorescence modulation of 1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione by silver nanoparticles and its possible analytical application.

  Luminescence : the journal of biological and chemical luminescence 20120101

• Oral delivery of curcumin bound to chitosan nanoparticles cured Plasmodium yoelii infected mice.

  Biotechnology advances 20120101

• Oral supplementation of turmeric decreases proteinuria, hematuria, and systolic blood pressure in patients suffering from relapsing or refractory lupus nephritis: a randomized and placebo-controlled study.

  Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 20120101

• Curcumin-like diarylpentanoid analogues as melanogenesis inhibitors.

  Journal of natural medicines 20120101

• Synergistic effects of piperine and curcumin in modulating benzo(a)pyrene induced redox imbalance in mice lungs.

  Toxicology mechanisms and methods 20120101

• Anti-inflammatory effects of curcumin in a murine model of chronic asthma.

  Allergologia et immunopathologia 20120101

• Lysosomal membrane permeabilization is involved in curcumin-induced apoptosis of A549 lung carcinoma cells.

  Molecular and cellular biochemistry 20120101

• Binding of curcumin to senile plaques and cerebral amyloid angiopathy in the aged brain of various animals and to neurofibrillary tangles in Alzheimer's brain.

  The Journal of veterinary medical science 20120101

• Design of curcumin loaded cellulose nanoparticles for prostate cancer.

  Current drug metabolism 20120101

• Inhibition of ecto-ATPase activity by curcumin in hepatocellular carcinoma HepG2 cells.

  The journal of physiological sciences : JPS 20120101

• The short-time treatment with curcumin sufficiently decreases cell viability, induces apoptosis and copper enhances these effects in multidrug-resistant K562/A02 cells.

  Molecular and cellular biochemistry 20120101

• Curcumin nanoformulations: a future nanomedicine for cancer.

  Drug discovery today 20120101

• In vitro drug treatments reduce the deleterious effects of aggregates containing polyAla expanded PHOX2B proteins.

  Neurobiology of disease 20120101

• Curcumin inhibits ox-LDL-induced MCP-1 expression by suppressing the p38MAPK and NF-κB pathways in rat vascular smooth muscle cells.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20120101

• Sensitizing human multiple myeloma cells to the proteasome inhibitor bortezomib by novel curcumin analogs.

  International journal of molecular medicine 20120101

• Solid cheese consumption: quantification of oral coating.

  Archives of oral biology 20120101

• Aminoguanidine and curcumin attenuated tumor necrosis factor (TNF)-α-induced oxidative stress, colitis and hepatotoxicity in mice.

  International immunopharmacology 20120101

• Curcumin inhibits interferon-γ signaling in colonic epithelial cells.

  American journal of physiology. Gastrointestinal and liver physiology 20120101

• Curcumin protects against ischemia/reperfusion injury in rat skeletal muscle.

  The Journal of surgical research 20120101

• Curcumin analogue CDF inhibits pancreatic tumor growth by switching on suppressor microRNAs and attenuating EZH2 expression.

  Cancer research 20120101

• Curcumin attenuates Concanavalin A-induced liver injury in mice by inhibition of Toll-like receptor (TLR) 2, TLR4 and TLR9 expression.

  International immunopharmacology 20120101

• Dendrosomal curcumin significantly suppresses cancer cell proliferation in vitro and in vivo.

  International immunopharmacology 20120101

• Curcumins promote monocytic gene expression related to β-amyloid and superoxide dismutase clearance.

  Neuro-degenerative diseases 20120101

• Preventive effects of curcumin on the development of azoxymethane-induced colonic preneoplastic lesions in male C57BL/KsJ-db/db obese mice.

  Nutrition and cancer 20120101

• Protective effect of curcumin against arsenic-induced apoptosis in murine splenocytes in vitro.

  Journal of immunotoxicology 20120101

• Stabilization of emulsion and butter like products containing essential fatty acids using kalonji seeds extract and curcuminoids.

  Journal of oleo science 20120101

• High-sensitivity determination of curcumin in human urine using gemini zwitterionic surfactant as a probe by resonance light scattering technique.

  Phytochemical analysis : PCA 20120101

• Effect of curcumin on liposome: curcumin as a molecular probe for monitoring interaction of ionic liquids with 1,2-dipalmitoyl-sn-glycero-3-phosphocholine liposome.

  Photochemistry and photobiology 20120101

• Resveratrol and diallyl disulfide enhance curcumin-induced sarcoma cell apoptosis.

  Frontiers in bioscience (Landmark edition) 20120101

• Lipidome analysis reveals antifungal polyphenol curcumin affects membrane lipid homeostasis.

  Frontiers in bioscience (Elite edition) 20120101

• Curcumin: the multi-targeted therapy for cancer regression.

  Frontiers in bioscience (Scholar edition) 20120101

• Curcumin-glucoside, a novel synthetic derivative of curcumin, inhibits α-synuclein oligomer formation: relevance to Parkinson's disease.

  Current pharmaceutical design 20120101

• Curcumin: a potential neuroprotective agent in Parkinson's disease.

  Current pharmaceutical design 20120101

• Curcumin prevents high fat diet induced insulin resistance and obesity via attenuating lipogenesis in liver and inflammatory pathway in adipocytes.

  PloS one 20120101

• A novel folate-modified self-microemulsifying drug delivery system of curcumin for colon targeting.

  International journal of nanomedicine 20120101

• Curcumin-arteether combination therapy of Plasmodium berghei-infected mice prevents recrudescence through immunomodulation.

  PloS one 20120101

• Anaphase-promoting complex/cyclosome protein Cdc27 is a target for curcumin-induced cell cycle arrest and apoptosis.

  BMC cancer 20120101

• A novel drug delivery system of oral curcumin markedly improves efficacy of treatment for heart failure after myocardial infarction in rats.

  Biological & pharmaceutical bulletin 20120101

• Pre-treatment with curcumin enhances plasma concentrations of losartan and its metabolite EXP3174 in rats.

  Biological & pharmaceutical bulletin 20120101

• Evaluation of antidepressant-like activity of novel water-soluble curcumin formulations and St. John's wort in behavioral paradigms of despair.

  Pharmacology 20120101

• Alzheimer's disease in the retina: imaging retinal aβ plaques for early diagnosis and therapy assessment.

  Neuro-degenerative diseases 20120101

• Curcumin promotes A-beta fibrillation and reduces neurotoxicity in transgenic Drosophila.

  PloS one 20120101

• ASC-J9 suppresses castration-resistant prostate cancer growth through degradation of full-length and splice variant androgen receptors.

  Neoplasia (New York, N.Y.) 20120101

• Curcumin enhances neurogenesis and cognition in aged rats: implications for transcriptional interactions related to growth and synaptic plasticity.

  PloS one 20120101

• Curcumin induces cell death in esophageal cancer cells through modulating Notch signaling.

  PloS one 20120101

• In vitro suppression of oral squamous cell carcinoma growth by ultrasound-mediated delivery of curcumin microemulsions.

  International journal of nanomedicine 20120101

• Curcumin loaded-PLGA nanoparticles conjugated with Tet-1 peptide for potential use in Alzheimer's disease.

  PloS one 20120101

• Neuronal uptake and neuroprotective effect of curcumin-loaded PLGA nanoparticles on the human SK-N-SH cell line.

  Journal of Alzheimer's disease : JAD 20120101

• Dendrimers bind antioxidant polyphenols and cisplatin drug.

  PloS one 20120101

• Aromatic hydroxyl group plays a critical role in antibacterial activity of the curcumin analogues.

  Natural product communications 20120101

• Epithelial proinflammatory response and curcumin-mediated protection from staphylococcal toxic shock syndrome toxin-1.

  PloS one 20120101

• Effect of curcumin on lipid peroxidation, early ultrastructural findings and neurological recovery after experimental spinal cord contusion injury in rats.

  Turkish neurosurgery 20120101

• A chemical analog of curcumin as an improved inhibitor of amyloid Abeta oligomerization.

  PloS one 20120101

• Curcumin induces the apoptosis of human monocytic leukemia THP-1 cells via the activation of JNK/ERK pathways.

  BMC complementary and alternative medicine 20120101

• Semaphorin 3A suppresses tumor growth and metastasis in mice melanoma model.

  PloS one 20120101

• Anticancer activities against cholangiocarcinoma, toxicity and pharmacological activities of Thai medicinal plants in animal models.

  BMC complementary and alternative medicine 20120101

• Pure curcumin decreases the expression of WT1 by upregulation of miR-15a and miR-16-1 in leukemic cells.

  Journal of experimental & clinical cancer research : CR 20120101

• Prooxidant-induced glutathione antioxidant response in vitro and in vivo: a comparative study between schisandrin B and curcumin.

  Biological & pharmaceutical bulletin 20120101

• Folate decorated dual drug loaded nanoparticle: role of curcumin in enhancing therapeutic potential of nutlin-3a by reversing multidrug resistance.

  PloS one 20120101

• Improvement of neuropathology and transcriptional deficits in CAG 140 knock-in mice supports a beneficial effect of dietary curcumin in Huntington's disease.

  Molecular neurodegeneration 20120101

• BDMC33, A curcumin derivative suppresses inflammatory responses in macrophage-like cellular system: role of inhibition in NF-κB and MAPK signaling pathways.

  International journal of molecular sciences 20120101

• Curcumin: updated molecular mechanisms and intervention targets in human lung cancer.

  International journal of molecular sciences 20120101

• Expression profile of genes regulated by curcumin in Y79 retinoblastoma cells.

  Nutrition and cancer 20120101

• Antifibrotic effect of curcumin in TGF-β 1-induced myofibroblasts from human oral mucosa.

  Asian Pacific journal of cancer prevention : APJCP 20120101

• Synthesis, release ability and bioactivity evaluation of chitin beads incorporated with curcumin for drug delivery applications.

  Journal of microencapsulation 20120101

• Curcumin attenuates β-catenin signaling in prostate cancer cells through activation of protein kinase D1.

  PloS one 20120101

• Curcumin protects retinal pigment epithelial cells against oxidative stress via induction of heme oxygenase-1 expression and reduction of reactive oxygen.

  Molecular vision 20120101

• Identification of curcumin targets in neuroinflammatory pathways: molecular docking scores with GSK-3β, p38 MAPK, COX, ICE and TACE enzymes.

  Acta poloniae pharmaceutica 20120101

• Spicy SDS-PAGE gels: curcumin/turmeric as an environment-friendly protein stain.

  Methods in molecular biology (Clifton, N.J.) 20120101

• Curcumin and curcuminoids in quest for medicinal status.

  Acta biochimica Polonica 20120101

• Scientific evidence and rationale for the development of curcumin and resveratrol as nutraceutricals for joint health.

  International journal of molecular sciences 20120101

• Injurious effects of curcumin on maturation of mouse oocytes, fertilization and fetal development via apoptosis.

  International journal of molecular sciences 20120101

• Curcumin enhances cytotoxic effects of bortezomib in human multiple myeloma H929 cells: potential roles of NF-κB/JNK.

  International journal of molecular sciences 20120101

• The role of nitric oxide on the responses of curcumin-treated rat aorta.

  Bratislavske lekarske listy 20120101

• Curcumin-loaded magnetic nanoparticles for breast cancer therapeutics and imaging applications.

  International journal of nanomedicine 20120101

• Combinatorial antitumor effect of naringenin and curcumin elicit angioinhibitory activities in vivo.

  Nutrition and cancer 20120101

• Curcumin blocks small cell lung cancer cells migration, invasion, angiogenesis, cell cycle and neoplasia through Janus kinase-STAT3 signalling pathway.

  PloS one 20120101

• A systemic administration of liposomal curcumin inhibits radiation pneumonitis and sensitizes lung carcinoma to radiation.

  International journal of nanomedicine 20120101

• Biliary excretion of curcumin is mediated by multidrug resistance-associated protein 2.

  Biological & pharmaceutical bulletin 20120101

• Curcumin attenuates gastric cancer induced by N-methyl-N-nitrosourea and saturated sodium chloride in rats.

  Journal of biomedicine & biotechnology 20120101

• Pleiotropic protective effects of phytochemicals in Alzheimer's disease.

  Oxidative medicine and cellular longevity 20120101

• Polyphenols: key issues involved in chemoprevention of prostate cancer.

  Oxidative medicine and cellular longevity 20120101

• Curcumin and other polyphenolic compounds in head and neck cancer chemoprevention.

  Oxidative medicine and cellular longevity 20120101

• Curcumin protects the seminal vesicles from metronidazole-induced reduction of secretion in mice.

  Acta medica (Hradec Kralove) 20120101

• [Effects of penetration enhancers on curcumin transdermal drug delivery].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20120101

• Effects of polymer molecular weight on relative oral bioavailability of curcumin.

  International journal of nanomedicine 20120101

• Protective effect of curcumin on pulmonary and cardiovascular effects induced by repeated exposure to diesel exhaust particles in mice.

  PloS one 20120101

• The three dimensional Quantitative Structure Activity Relationships (3D-QSAR) and docking studies of curcumin derivatives as androgen receptor antagonists.

  International journal of molecular sciences 20120101

• Polyphenols sensitization potentiates susceptibility of MCF-7 and MDA MB-231 cells to Centchroman.

  PloS one 20120101

• Curcuminoid binding to embryonal carcinoma cells: reductive metabolism, induction of apoptosis, senescence, and inhibition of cell proliferation.

  PloS one 20120101

• Design, synthesis and biological activity of new polyenolic inhibitors of matrix metalloproteinases: a focus on chemically-modified curcumins.

  Current medicinal chemistry 20120101

• pKa, zinc- and serum albumin-binding of curcumin and two novel biologically-active chemically-modified curcumins.

  Current medicinal chemistry 20120101

• Interleukin-1 induction of aggrecanase gene expression in human articular chondrocytes is mediated by mitogen-activated protein kinases.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101

• The toxicity of amyloid β oligomers.

  International journal of molecular sciences 20120101

• Curcumin suppresses ovalbumin-induced allergic conjunctivitis.

  Molecular vision 20120101

• Curcumin prevents formation of polyglutamine aggregates by inhibiting Vps36, a component of the ESCRT-II complex.

  PloS one 20120101

• Enhanced bioavailability and efficiency of curcumin for the treatment of asthma by its formulation in solid lipid nanoparticles.

  International journal of nanomedicine 20120101

• Cross-linked acrylic hydrogel for the controlled delivery of hydrophobic drugs in cancer therapy.

  International journal of nanomedicine 20120101

• Preparation and in vivo pharmacokinetics of curcumin-loaded PCL-PEG-PCL triblock copolymeric nanoparticles.

  International journal of nanomedicine 20120101

• Role of curcumin in mesenteric ischemia - reperfusion injury in rats.

  Bratislavske lekarske listy 20120101

• Plant polyphenols in prevention of heart disease.

  Bratislavske lekarske listy 20120101

• Structurally modified curcumin analogs inhibit STAT3 phosphorylation and promote apoptosis of human renal cell carcinoma and melanoma cell lines.

  PloS one 20120101

• Effects of diet and/or exercise in enhancing spinal cord sensorimotor learning.

  PloS one 20120101

• Novel dipeptide nanoparticles for effective curcumin delivery.

  International journal of nanomedicine 20120101

• Curcumin induces Nrf2 nuclear translocation and prevents glomerular hypertension, hyperfiltration, oxidant stress, and the decrease in antioxidant enzymes in 5/6 nephrectomized rats.

  Oxidative medicine and cellular longevity 20120101

• Novel micelle formulation of curcumin for enhancing antitumor activity and inhibiting colorectal cancer stem cells.

  International journal of nanomedicine 20120101

• Curcumin inhibits glutamate release from rat prefrontal nerve endings by affecting vesicle mobilization.

  International journal of molecular sciences 20120101

• Effects of curcumin and capsaicin irradiated with visible light on murine oral mucosa.

  In vivo (Athens, Greece) 20120101

• Curcumin and inflammatory bowel disease: biological mechanisms and clinical implication.

  Digestion 20120101

• Antibacterial and antiinflammatory kinetics of curcumin as a potential antimucositis agent in cancer patients.

  Nutrition and cancer 20120101

• Antimicrobial activity of curcumin-loaded myristic acid microemulsions against Staphylococcus epidermidis.

  Chemical & pharmaceutical bulletin 20120101

• Expression of miR-34 is lost in colon cancer which can be re-expressed by a novel agent CDF.

  Journal of hematology & oncology 20120101

• Curcumin effect on MMPs and TIMPs genes in a breast cancer cell line.

  Asian Pacific journal of cancer prevention : APJCP 20120101

• Native and β-cyclodextrin-enclosed curcumin: entrapment within liposomes and their in vitro cytotoxicity in lung and colon cancer.

  Drug delivery 20120101

• Comparative evaluation of the efficacy of turmeric and curcumin as a local drug delivery system: a clinicomicrobiological study.

  General dentistry 20120101

• Insulin catalyzes the curcumin-induced wound healing: an in vitro model for gingival repair.

  Indian journal of pharmacology 20120101

• An optimized molecular inclusion complex of diferuloylmethane: enhanced physical properties and biological activity.

  International journal of nanomedicine 20120101

• In vitro characterization and in vivo evaluation of nanostructured lipid curcumin carriers for intragastric administration.

  International journal of nanomedicine 20120101

• Spicy approach to cancer treatment.

  Journal of the National Cancer Institute 20111221

• 'Clicked' sugar-curcumin conjugate: modulator of amyloid-β and tau peptide aggregation at ultralow concentrations.

  ACS chemical neuroscience 20111221

• Curcumin derivatives as new ligands of Aβ peptides.

  Journal of biotechnology 20111220

• STAT3 signaling pathway is necessary for cell survival and tumorsphere forming capacity in ALDH⁺/CD133⁺ stem cell-like human colon cancer cells.

  Biochemical and biophysical research communications 20111216

• Screening medicinal plants for the detection of novel antimalarial products applying the inhibition of β-hematin formation.

  Journal of pharmaceutical and biomedical analysis 20111215

• Suppression of pro-inflammatory and proliferative pathways by diferuloylmethane (curcumin) and its analogues dibenzoylmethane, dibenzoylpropane, and dibenzylideneacetone: role of Michael acceptors and Michael donors.

  Biochemical pharmacology 20111215

• Scavenging mechanism of curcumin toward the hydroxyl radical: a theoretical study of reactions producing ferulic acid and vanillin.

  The journal of physical chemistry. A 20111215

• Artificial protein block polymer libraries bearing two SADs: effects of elastin domain repeats.

  Biomacromolecules 20111212

• Curcumin differentially regulates endoplasmic reticulum stress through transcriptional corepressor SMILE (small heterodimer partner-interacting leucine zipper protein)-mediated inhibition of CREBH (cAMP responsive element-binding protein H).

  The Journal of biological chemistry 20111209

• Curcumin enhances the efficacy of chemotherapy by tailoring p65NFκB-p300 cross-talk in favor of p53-p300 in breast cancer.

  The Journal of biological chemistry 20111209

• Newly synthesized curcumin derivatives: crosstalk between chemico-physical properties and biological activity.

  Journal of medicinal chemistry 20111208

• Enhanced drug loading on magnetic nanoparticles by layer-by-layer assembly using drug conjugates: blood compatibility evaluation and targeted drug delivery in cancer cells.

  Langmuir : the ACS journal of surfaces and colloids 20111206

• Spectrometric study on the interaction of dodecyltrimethylammonium bromide with curcumin.

  Langmuir : the ACS journal of surfaces and colloids 20111206

• HDAC1/NFκB pathway is involved in curcumin inhibiting of Tat-mediated long terminal repeat transactivation.

  Journal of cellular physiology 20111201

• Curcumin and a Morus alba extract reduce pro-inflammatory effects of resistin in human endothelial cells.

  Phytotherapy research : PTR 20111201

• Curcumin, myrecen and cineol modulate the percentage of lymphocyte subsets altered by 2,3,7, 8-tetracholorodibenzo-p-dioxins (TCDD) in rats.

  Human & experimental toxicology 20111201

• Aromatic-turmerone inhibits α-MSH and IBMX-induced melanogenesis by inactivating CREB and MITF signaling pathways.

  Archives of dermatological research 20111201

• Efficacy of turmeric (curcumin) in pain and postoperative fatigue after laparoscopic cholecystectomy: a double-blind, randomized placebo-controlled study.

  Surgical endoscopy 20111201

• Curcumin protects mice against concanavalin A-induced hepatitis by inhibiting intrahepatic intercellular adhesion molecule-1 (ICAM-1) and CXCL10 expression.

  Molecular and cellular biochemistry 20111201

• Curcumin promotes cholesterol efflux from adipocytes related to PPARgamma-LXRalpha-ABCA1 passway.

  Molecular and cellular biochemistry 20111201

• Curcumin protects from cardiac reperfusion damage by attenuation of oxidant stress and mitochondrial dysfunction.

  Cardiovascular toxicology 20111201

• Neuroprotection and sensorimotor functional improvement by curcumin after intracerebral hemorrhage in mice.

  Journal of neurotrauma 20111201

• Topical curcumin for the healing of carbon dioxide laser skin wounds in mice.

  Photomedicine and laser surgery 20111201

• Neuroprotective efficacy of curcumin in arsenic induced cholinergic dysfunctions in rats.

  Neurotoxicology 20111201

• Effects of different carboxylic ester spacers on chemical stability, release characteristics, and anticancer activity of mono-PEGylated curcumin conjugates.

  Journal of pharmaceutical sciences 20111201

• Induction of apoptotic death by curcumin in human tongue squamous cell carcinoma SCC-4 cells is mediated through endoplasmic reticulum stress and mitochondria-dependent pathways.

  Cell biochemistry and function 20111201

• Tetrahydrocurcumin is more effective than curcumin in preventing azoxymethane-induced colon carcinogenesis.

  Molecular nutrition & food research 20111201

• Submicroparticles composed of amphiphilic chitosan derivative for oral insulin and curcumin release applications.

  Colloids and surfaces. B, Biointerfaces 20111201

• Vascular anti-inflammatory effects of curcumin on HMGB1-mediated responses in vitro.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20111201

• Neuroprotective effect of curcumin in an experimental rat model of subarachnoid hemorrhage.

  Anesthesiology 20111201

• The effect of curcumin in the ectonucleotidases and acetylcholinesterase activities in synaptosomes from the cerebral cortex of cigarette smoke-exposed rats.

  Cell biochemistry and function 20111201

• Comment on Jia et al.

  The British journal of nutrition 20111201

• Epigenetic CpG demethylation of the promoter and reactivation of the expression of Neurog1 by curcumin in prostate LNCaP cells.

  The AAPS journal 20111201

• Prevention and treatment of Schistosoma mansoni-induced liver fibrosis in mice.

  Inflammopharmacology 20111201

• The role of curcumin on intestinal oxidative stress, cell proliferation and apoptosis after ischemia/reperfusion injury in rats.

  Journal of molecular histology 20111201

• Sphingosine kinase-1 pathway mediates high glucose-induced fibronectin expression in glomerular mesangial cells.

  Molecular endocrinology (Baltimore, Md.) 20111201

• In vitro effect on cancer cells: synthesis and preparation of polyurethane membranes for controlled delivery of curcumin.

  Journal of biomedical materials research. Part A 20111201

• Comparative evaluation of anti-inflammatory properties of thymoquinone and curcumin using an asthmatic murine model.

  International immunopharmacology 20111201

• Long-term curcumin administration protects against atherosclerosis via hepatic regulation of lipoprotein cholesterol metabolism.

  Molecular nutrition & food research 20111201

• Curcumin: a potential therapeutic polyphenol, prevents noradrenaline-induced hypertrophy in rat cardiac myocytes.

  The Journal of pharmacy and pharmacology 20111201

• Protective mechanism of curcumin against Vibrio vulnificus infection.

  FEMS immunology and medical microbiology 20111201

• Curcumin induces Apaf-1-dependent, p21-mediated caspase activation and apoptosis.

  Cell cycle (Georgetown, Tex.) 20111201

• Effects of curcumin on the activities of the enzymes that hydrolyse adenine nucleotides in platelets from cigarette smoke-exposed rats.

  Cell biochemistry and function 20111201

• Curcumin, but not Prima-1, decreased tumor cell proliferation in the syngeneic murine orthotopic bladder tumor model.

  Clinics (Sao Paulo, Brazil) 20111201

• Ferric reducing, antiradical and beta-carotene bleaching activities of nicotinic acid and picolinic acid bioconjugates of curcumin.

  Natural product communications 20111201

• Ameliorative effects of curcumin against renal injuries mediated by inducible nitric oxide synthase and nuclear factor kappa B during gentamicin-induced toxicity in Wistar rats.

  European journal of pharmacology 20111130

• Challenges associated with curcumin therapy in Alzheimer disease.

  Expert reviews in molecular medicine 20111104

• Ameliorative effects of curcumin on the structural parameters of seminiferous tubules and Leydig cells in metronidazole-treated mice: a stereological approach.

  Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20111101

• Effect of combined treatment with curcumin and candesartan on ischemic brain damage in mice.

  Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 20111101

• Molecular dynamics simulations and binding free energy analysis of DNA minor groove complexes of curcumin.

  Journal of molecular modeling 20111101

• Evaluation of turmeric extract on performance indices impressed by induced aflatoxicosis in broiler chickens.

  Toxicology and industrial health 20111101

• Curcumin suppresses growth of mesothelioma cells in vitro and in vivo, in part, by stimulating apoptosis.

  Molecular and cellular biochemistry 20111101

• Curcumin ameliorates reserpine-induced pain-depression dyad: behavioural, biochemical, neurochemical and molecular evidences.

  Psychoneuroendocrinology 20111101

• Curcumin attenuates aluminum-induced oxidative stress and mitochondrial dysfunction in rat brain.

  Neurotoxicity research 20111101

• Dietary phytochemicals induce p53- and caspase-independent cell death in human neuroblastoma cells.

  International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20111101

• Curcumin protects against ovariectomy-induced bone loss and decreases osteoclastogenesis.

  Journal of cellular biochemistry 20111101

• The neuroprotective effect of curcumin and Nigella sativa oil against oxidative stress in the pilocarpine model of epilepsy: a comparison with valproate.

  Neurochemical research 20111101

• Interaction of curcumin with lipid monolayers and liposomal bilayers.

  Colloids and surfaces. B, Biointerfaces 20111101

• Pharmacodynamics of curcumin as DNA hypomethylation agent in restoring the expression of Nrf2 via promoter CpGs demethylation.

  Biochemical pharmacology 20111101

• Effect of different curcuminoid supplement dosages on total in vivo antioxidant capacity and cholesterol levels of healthy human subjects.

  Phytotherapy research : PTR 20111101

• Curcumin reverses chemoresistance of human gastric cancer cells by downregulating the NF-κB transcription factor.

  Oncology reports 20111101

• Lung-targeted delivery system of curcumin loaded gelatin microspheres.

  Drug delivery 20111101

• Curcumin augments lung maturation, preventing neonatal lung injury by inhibiting TGF-β signaling.

  American journal of physiology. Lung cellular and molecular physiology 20111101

• Combined effects of curcumin and piperine in ameliorating benzo(a)pyrene induced DNA damage.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20111101

• Indole-3-carbinol enhances the resolution of rat liver fibrosis and stimulates hepatic stellate cell apoptosis by blocking the inhibitor of κB kinase α/inhibitor of κB-α/nuclear factor-κB pathway.

  The Journal of pharmacology and experimental therapeutics 20111101

• Targeting curcusomes to inflammatory dendritic cells inhibits NF-κB and improves insulin resistance in obese mice.

  Diabetes 20111101

• HO-3867, a curcumin analog, sensitizes cisplatin-resistant ovarian carcinoma, leading to therapeutic synergy through STAT3 inhibition.

  Cancer biology & therapy 20111101

• Evaluating potential of curcumin loaded solid lipid nanoparticles in aluminium induced behavioural, biochemical and histopathological alterations in mice brain.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20111101

• C086, a novel analog of curcumin, induces growth inhibition and down-regulation of NFκB in colon cancer cells and xenograft tumors.

  Cancer biology & therapy 20111101

• Combining curcumin (diferuloylmethane) and heat shock protein inhibition for neurofibromatosis 2 treatment: analysis of response and resistance pathways.

  Molecular cancer therapeutics 20111101

• Curcumin inhibits growth of Saccharomyces cerevisiae through iron chelation.

  Eukaryotic cell 20111101

• Investigations on membrane perturbation by chrysin and its copper complex using self-assembled lipid bilayers.

  Langmuir : the ACS journal of surfaces and colloids 20111101

• Tetrahydrocurcumin, a major metabolite of curcumin, induced autophagic cell death through coordinative modulation of PI3K/Akt-mTOR and MAPK signaling pathways in human leukemia HL-60 cells.

  Molecular nutrition & food research 20111101

• The hypomethylation agent bisdemethoxycurcumin acts on the WIF-1 promoter, inhibits the canonical Wnt pathway and induces apoptosis in human non-small-cell lung cancer.

  Current cancer drug targets 20111101

• Extending the applicability of pressurized hot water extraction to compounds exhibiting limited water solubility by pH control: curcumin from the turmeric rhizome.

  Analytical and bioanalytical chemistry 20111101

• Curcumin provides potential protection against the activation of hypoxia and prolyl 4-hydroxylase inhibitors on prostate-specific antigen expression in human prostate carcinoma cells.

  Molecular nutrition & food research 20111101

• Multifaceted roles of curcumin: two sides of a coin!

  Expert opinion on biological therapy 20111101

• Modulators of induction of plasminogen activator inhibitor type-1 in HepG2 cells by transforming growth factor-β.

  Coronary artery disease 20111101

• Binding of isoxazole and pyrazole derivatives of curcumin with the activator binding domain of novel protein kinase C.

  Bioorganic & medicinal chemistry 20111101

• Multitargeting by curcumin as revealed by molecular interaction studies.

  Natural product reports 20111101

• Curcuma as a functional food in the control of cancer and inflammation.

  Current opinion in clinical nutrition and metabolic care 20111101

• Curcumin enhanced antiproliferative effect of mitomycin C in human breast cancer MCF-7 cells in vitro and in vivo.

  Acta pharmacologica Sinica 20111101

• Susceptibility of clinical isolates of Candida to photodynamic effects of curcumin.

  Lasers in surgery and medicine 20111101

• Xenografts in zebrafish embryos as a rapid functional assay for breast cancer stem-like cell identification.

  Cell cycle (Georgetown, Tex.) 20111101

• Curcumin attenuates diabetic nephropathy by inhibiting PKC-α and PKC-β1 activity in streptozotocin-induced type I diabetic rats.

  Molecular nutrition & food research 20111101

• Anti-proliferative effect of curcumin on melanoma cells is mediated by PDE1A inhibition that regulates the epigenetic integrator UHRF1.

  Molecular nutrition & food research 20111101

• [Study on functions and mechanism of curcumin in inducing gastric carcinoma BGC apoptosis].

  Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20111101

• Up-regulation of NF-kB-sensitive miRNA-125b and miRNA-146a in metal sulfate-stressed human astroglial (HAG) primary cell cultures.

  Journal of inorganic biochemistry 20111101

• Novel curcumin analogs, GO-Y030 and GO-Y078, are multi-targeted agents with enhanced abilities for multiple myeloma.

  Anticancer research 20111101

• Specificity protein, Sp1-mediated increased expression of Prdx6 as a curcumin-induced antioxidant defense in lens epithelial cells against oxidative stress.

  Cell death & disease 20111101

• Tetrahydrocurcumin extends life span and inhibits the oxidative stress response by regulating the FOXO forkhead transcription factor.

  Aging 20111101

• Preventive action of curcumin in experimental acute pancreatitis in mouse.

  The Indian journal of medical research 20111101

• Increase of therapeutic activity of doxorubicin by long circulating liposomes in combination with curcumin.

  Die Pharmazie 20111101

• Cytotoxic activity and cell cycle analysis of hexahydrocurcumin on SW 480 human colorectal cancer cells.

  Natural product communications 20111101

• [Chemopreventive effect of boswellic acid and curcumin on 7,12-dimethyl benzanthracene-induced hamster cheek pouch carcinogenesis].

  Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology 20111101

• An experimental study on the effects of curcumin on posterior capsule opacification in young rabbit eyes.

  Chinese medical journal 20111101

• [Protective effects of curcumin on vascular endothelial injuries induced by radiation].

  Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20111101

• [Preparation of curcumin solid dispersion and inclusion complex].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20111101

• Effect of curcumin on LDL oxidation in vitro, and lipid peroxidation and antioxidant enzymes in cholesterol fed rabbits.

  International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20111101

• Transactivation of gene expression by NF-κB is dependent on thioredoxin reductase activity.

  Free radical biology & medicine 20111015

• Curcumin prevents Cr(VI)-induced renal oxidant damage by a mitochondrial pathway.

  Free radical biology & medicine 20111015

• Solid-state NMR analysis of interaction sites of curcumin and 42-residue amyloid β-protein fibrils.

  Bioorganic & medicinal chemistry 20111015

• Temperature dependence of the fluorescence properties of curcumin.

  The journal of physical chemistry. A 20111013

• Curcumin ((E,E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione) activates and desensitizes the nociceptor ion channel TRPA1.

  Neuroscience letters 20111010

• The tumor suppressor p33ING1b upregulates p16INK4a expression and induces cellular senescence.

  FEBS letters 20111003

• Effect of intraperitoneal injection of curcumin on food intake in a goldfish model.

  Journal of molecular neuroscience : MN 20111001

• Protective effect of curcumin and its combination with piperine (bioavailability enhancer) against haloperidol-associated neurotoxicity: cellular and neurochemical evidence.

  Neurotoxicity research 20111001

• Curcumin inhibits adipocyte differentiation through modulation of mitotic clonal expansion.

  The Journal of nutritional biochemistry 20111001

• Synthesis and biological evaluation of novel N,N'-bis-methylenedioxybenzyl-alkylenediamines as bivalent anti-Alzheimer disease ligands.

  Journal of enzyme inhibition and medicinal chemistry 20111001

• A simple RP-HPLC method for the simultaneous determination of curcumin and its prodrug, curcumin didecanoate, in rat plasma and the application to pharmacokinetic study.

  Biomedical chromatography : BMC 20111001

• Curcumin induces stress response and hormetically modulates wound healing ability of human skin fibroblasts undergoing ageing in vitro.

  Biogerontology 20111001

• [DLys(6)]-luteinizing hormone releasing hormone-curcumin conjugate inhibits pancreatic cancer cell growth in vitro and in vivo.

  International journal of cancer 20111001

• Modulation of Nrf2/ARE pathway by food polyphenols: a nutritional neuroprotective strategy for cognitive and neurodegenerative disorders.

  Molecular neurobiology 20111001

• Hyaluronan-binding protein 1 (HABP1/p32/gC1qR) induces melanoma cell migration and tumor growth by NF-kappa B dependent MMP-2 activation through integrin α(v)β(3) interaction.

  Cellular signalling 20111001

• Functionalization of liposomes with ApoE-derived peptides at different density affects cellular uptake and drug transport across a blood-brain barrier model.

  Nanomedicine : nanotechnology, biology, and medicine 20111001

• Synergistic activity of curcumin with methotrexate in ameliorating Freund's Complete Adjuvant induced arthritis with reduced hepatotoxicity in experimental animals.

  European journal of pharmacology 20111001

• Impact of curcumin, raspberry extract, and neem leaf extract on rel protein-regulated cell death/radiosensitization in pancreatic cancer cells.

  Pancreas 20111001

• Effect of curcumin-associated and lipid ligand-functionalized nanoliposomes on aggregation of the Alzheimer's Aβ peptide.

  Nanomedicine : nanotechnology, biology, and medicine 20111001

• Protective role of curcumin in oxidative stress of breast cells.

  Oncology reports 20111001

• Curcumin-induced mitotic spindle defect and cell cycle arrest in human bladder cancer cells occurs partly through inhibition of aurora A.

  Molecular pharmacology 20111001

• Curcumin induces apoptosis in a murine mammary gland adenocarcinoma cell line through the mitochondrial pathway.

  European journal of pharmacology 20111001

• Inhibition of cardiac oxidative and endoplasmic reticulum stress-mediated apoptosis by curcumin treatment contributes to protection against acute myocarditis.

  Free radical research 20111001

• Curcumin modulates microRNA-203-mediated regulation of the Src-Akt axis in bladder cancer.

  Cancer prevention research (Philadelphia, Pa.) 20111001

• Curcumin-mediated lifespan extension in Caenorhabditis elegans.

  Mechanisms of ageing and development 20111001

• Synthesis and evaluation of 1-(4-[¹⁸F]fluoroethyl)-7-(4'-methyl)curcumin with improved brain permeability for β-amyloid plaque imaging.

  Bioorganic & medicinal chemistry letters 20111001

• Delineating Alzheimer's disease progression with MGAT3, a biomarker for improved prognosis and personalized therapy.

  Biomarkers in medicine 20111001

• Effect of citrus polyphenol- and curcumin-supplemented diet on inflammatory state in obese cats.

  The British journal of nutrition 20111001

• [Study on the preparation of curcumin inclusion complex and its stability].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20111001

• Curcumin sensitizes chemotherapeutic drugs via modulation of PKC, telomerase, NF-kappaB and HDAC in breast cancer.

  Therapeutic delivery 20111001

• Curcumin recognizes a unique binding site of tubulin.

  Journal of medicinal chemistry 20110922

• Dimethoxycurcumin, a metabolically stable analogue of curcumin, exhibits anti-inflammatory activities in murine and human lymphocytes.

  Biochemical pharmacology 20110915

• Curcumin and its nano-formulation: the kinetics of tissue distribution and blood-brain barrier penetration.

  International journal of pharmaceutics 20110915

• Curcumin enhances the mitomycin C-induced cytotoxicity via downregulation of MKK1/2-ERK1/2-mediated Rad51 expression in non-small cell lung cancer cells.

  Toxicology and applied pharmacology 20110915

• Photoinduced trans-to-cis isomerization of cyclocurcumin.

  The journal of physical chemistry. B 20110915

• Curcumin protects the dorsal root ganglion and sciatic nerve after crush in rat.

  Pathology, research and practice 20110915

• Curcumin treatment suppresses IKKβ kinase activity of salivary cells of patients with head and neck cancer: a pilot study.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20110915

• Design, synthesis, and biological evaluation of curcumin analogues as multifunctional agents for the treatment of Alzheimer's disease.

  Bioorganic & medicinal chemistry 20110915

• Metabolic and pharmacokinetic studies of curcumin, demethoxycurcumin and bisdemethoxycurcumin in mice tumor after intragastric administration of nanoparticle formulations by liquid chromatography coupled with tandem mass spectrometry.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110915

• PLGA nanoparticles improve the oral bioavailability of curcumin in rats: characterizations and mechanisms.

  Journal of agricultural and food chemistry 20110914

• Investigation of the absorption mechanism of solubilized curcumin using Caco-2 cell monolayers.

  Journal of agricultural and food chemistry 20110914

• Modulatory effects of curcumin on multi-drug resistance-associated protein 5 in pancreatic cancer cells.

  Cancer chemotherapy and pharmacology 20110901

• Sensitization to TRAIL-induced apoptosis in human neuroblastoma SK-N-AS cells by NF-κB inhibitors is dependent on reactive oxygen species (ROS).

  Journal of neuro-oncology 20110901

• Effect of curcumin and irradiation in PE/CA-PJ15 oral squamous cell carcinoma.

  Acta odontologica Scandinavica 20110901

• Nutritional compounds influence tissue factor expression and inflammation of chronic kidney disease patients in vitro.

  Nutrition (Burbank, Los Angeles County, Calif.) 20110901

• Implications of cancer stem cell theory for cancer chemoprevention by natural dietary compounds.

  The Journal of nutritional biochemistry 20110901

• Curcumin suppresses proliferation and induces apoptosis in human biliary cancer cells through modulation of multiple cell signaling pathways.

  Carcinogenesis 20110901

• Low-dose curcumin leads to the inhibition of tumor growth via enhancing CTL-mediated antitumor immunity.

  International immunopharmacology 20110901

• Curcumin stimulates proliferation, stemness acting signals and migration of 3T3-L1 preadipocytes.

  International journal of molecular medicine 20110901

• Encapsulation of curcumin in self-assembling peptide hydrogels as injectable drug delivery vehicles.

  Biomaterials 20110901

• Synchronous fluorescence spectroscopic study of solvatochromic curcumin dye.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20110901

• Curcumin improves MMC-based chemotherapy by simultaneously sensitising cancer cells to MMC and reducing MMC-associated side-effects.

  European journal of cancer (Oxford, England : 1990) 20110901

• Curcumin and resveratrol synergistically stimulate p21 and regulate cox-2 by maintaining adequate zinc levels during lung carcinogenesis.

  European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 20110901

• Pharmacokinetic and pharmacodynamic interactions of valproate, phenytoin, phenobarbitone and carbamazepine with curcumin in experimental models of epilepsy in rats.

  Pharmacology, biochemistry, and behavior 20110901

• Supramolecular assembled nanogel made of mannan.

  Journal of colloid and interface science 20110901

• Unique role of ionic liquid [bmin][BF4] during curcumin-surfactant association and micellization of cationic, anionic and non-ionic surfactant solutions.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20110901

• Curcumin prevents corticosterone-induced neurotoxicity and abnormalities of neuroplasticity via 5-HT receptor pathway.

  Journal of neurochemistry 20110901

• A polymeric nanoparticle formulation of curcumin (NanoCurc™) ameliorates CCl4-induced hepatic injury and fibrosis through reduction of pro-inflammatory cytokines and stellate cell activation.

  Laboratory investigation; a journal of technical methods and pathology 20110901

• Study binding of Al-curcumin complex to ds-DNA, monitoring by multispectroscopic and voltammetric techniques.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20110901

• Curcumin modulates PKCα activity by a membrane-dependent effect.

  Archives of biochemistry and biophysics 20110901

• Potential interaction of natural dietary bioactive compounds with COX-2.

  Journal of molecular graphics & modelling 20110901

• Preparation of curcumin loaded poly(ε-caprolactone)-poly(ethylene glycol)-poly(ε-caprolactone) nanofibers and their in vitro antitumor activity against Glioma 9L cells.

  Nanoscale 20110901

• Mango ginger (Curcuma amada Roxb.)--a promising spice for phytochemicals and biological activities.

  Journal of biosciences 20110901

• [Effect of curcumin on IL-17-induced nitric oxide production and expression of iNOS in human keratinocytes].

  Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20110901

• Caspase dependent programmed cell death in developing embryos: a potential target for therapeutic intervention against pathogenic nematodes.

  PLoS neglected tropical diseases 20110901

• Molecular docking studies of curcumin analogs with phospholipase A2.

  Interdisciplinary sciences, computational life sciences 20110901

• [Effects of curcumin on the epithelial mesenchymal transition and TGF-beta/Smads signaling pathway in unilateral ureteral obstruction rats].

  Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20110901

• Curcumin associated magnetite nanoparticles inhibit in vitro melanoma cell growth.

  Journal of nanoscience and nanotechnology 20110901

• Potential role of curcumin phytosome (Meriva) in controlling the evolution of diabetic microangiopathy. A pilot study.

  Panminerva medica 20110901

• [Curcumin down-regulates CX3CR1 expression in spinal cord dorsal horn and DRG in neuropathic pain rats].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110901

• Curcumin inhibits the migration and invasion of mouse hepatoma Hca-F cells through down-regulating caveolin-1 expression and epidermal growth factor receptor signaling.

  IUBMB life 20110901

• Rescue of ATP7B function in hepatocyte-like cells from Wilson's disease induced pluripotent stem cells using gene therapy or the chaperone drug curcumin.

  Human molecular genetics 20110815

• Curcumin inhibits glutamate release in nerve terminals from rat prefrontal cortex: possible relevance to its antidepressant mechanism.

  Progress in neuro-psychopharmacology & biological psychiatry 20110815

• Fumigaclavine C inhibits tumor necrosis factor α production via suppression of toll-like receptor 4 and nuclear factor κB activation in macrophages.

  Life sciences 20110815

• Curcumin modulates nuclear factor kappaB (NF-kappaB)-mediated inflammation in human tenocytes in vitro: role of the phosphatidylinositol 3-kinase/Akt pathway.

  The Journal of biological chemistry 20110812

• Curcumin suppresses TGF-β signaling by inhibition of TGIF degradation in scleroderma fibroblasts.

  Biochemical and biophysical research communications 20110812

• Synthesis of N-substituted 3,5-bis(arylidene)-4-piperidones with high antitumor and antioxidant activity.

  Journal of medicinal chemistry 20110811

• Natural polyphenols inhibit different steps of the process of transthyretin (TTR) amyloid fibril formation.

  FEBS letters 20110804

• Ameliorating effect of N-acetylcysteine and curcumin on pesticide-induced oxidative DNA damage in human peripheral blood mononuclear cells.

  Environmental monitoring and assessment 20110801

• Curcumin prevents haloperidol-induced development of abnormal oro-facial movements: possible implications of Bcl-XL in its mechanism of action.

  Synapse (New York, N.Y.) 20110801

• Comparative docking and CoMFA analysis of curcumine derivatives as HIV-1 integrase inhibitors.

  Molecular diversity 20110801

• Glucose-regulated protein 78 (GRP78) mediated the efficacy to curcumin treatment on hepatocellular carcinoma.

  Annals of surgical oncology 20110801

• Curcumin immune-mediated and anti-apoptotic mechanisms protect against renal ischemia/reperfusion and distant organ induced injuries.

  International immunopharmacology 20110801

• Multimicroscopic study of curcumin effect on fixed nonmalignant and cancerous mammalian epithelial cells.

  Journal of biophotonics 20110801

• Dietary fish oil and curcumin combine to modulate colonic cytokinetics and gene expression in dextran sodium sulphate-treated mice.

  The British journal of nutrition 20110801

• Bioactive antioxidant mixtures promote proliferation and migration on human oral fibroblasts.

  Archives of oral biology 20110801

• Activation and induction of cytosolic phospholipase A2 by TNF-α mediated through Nox2, MAPKs, NF-κB, and p300 in human tracheal smooth muscle cells.

  Journal of cellular physiology 20110801

• Curcumin mediates both dilation and constriction of peripheral arterioles via adrenergic receptors.

  The Journal of investigative dermatology 20110801

• Curcumin induces DNA damage and caffeine-insensitive cell cycle arrest in colorectal carcinoma HCT116 cells.

  Molecular and cellular biochemistry 20110801

• Biocompatible, biodegradable and thermo-sensitive chitosan-g-poly (N-isopropylacrylamide) nanocarrier for curcumin drug delivery.

  International journal of biological macromolecules 20110801

• Advanced drug delivery systems of curcumin for cancer chemoprevention.

  Cancer prevention research (Philadelphia, Pa.) 20110801

• Curcumin-loaded biocompatible thermoresponsive polymeric nanoparticles for cancer drug delivery.

  Journal of colloid and interface science 20110801

• Safety assessment of a solid lipid curcumin particle preparation: acute and subchronic toxicity studies.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110801

• Sustained targeting of Bcr-Abl + leukemia cells by synergistic action of dual drug loaded nanoparticles and its implication for leukemia therapy.

  Biomaterials 20110801

• Differential antioxidant/pro-oxidant activity of dimethoxycurcumin, a synthetic analogue of curcumin.

  Free radical research 20110801

• Apoptotic death in curcumin-treated NPC-TW 076 human nasopharyngeal carcinoma cells is mediated through the ROS, mitochondrial depolarization and caspase-3-dependent signaling responses.

  International journal of oncology 20110801

• Mantle cell lymphoma: curcumin nanodisks and possible new concepts on drug delivery for an incurable lymphoma.

  Leukemia & lymphoma 20110801

• Vitamin D receptor (VDR) regulation of voltage-gated chloride channels by ligands preferring a VDR-alternative pocket (VDR-AP).

  Molecular endocrinology (Baltimore, Md.) 20110801

• Fabrication of silver nanocomposite films impregnated with curcumin for superior antibacterial applications.

  Journal of materials science. Materials in medicine 20110801

• Curcumin nanodisk-induced apoptosis in mantle cell lymphoma.

  Leukemia & lymphoma 20110801

• Anti-tumor activity of curcumin against androgen-independent prostate cancer cells via inhibition of NF-κB and AP-1 pathway in vitro.

  Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20110801

• Curcumin loaded fibrinogen nanoparticles for cancer drug delivery.

  Journal of biomedical nanotechnology 20110801

• Preparation of curcuminoid niosomes for enhancement of skin permeation.

  Die Pharmazie 20110801

• [Therapeutic effect of indole-3-carbinol on pig serum-induced hepatic fibrosis in rats].

  Yao xue xue bao = Acta pharmaceutica Sinica 20110801

• Epigenetic diet: impact on the epigenome and cancer.

  Epigenomics 20110801

• Curcumin: the potential for efficacy in gastrointestinal diseases.

  Best practice & research. Clinical gastroenterology 20110801

• Effects of NF-κB blocker curcumin on oogenesis and immunocompetent organ cells in immune ovarian injury in mice.

  Bulletin of experimental biology and medicine 20110801

• Celastrol inhibits Tat-mediated human immunodeficiency virus (HIV) transcription and replication.

  Journal of molecular biology 20110729

• Inhalation with NDS27 attenuates pulmonary neutrophilic inflammation in recurrent airway obstruction.

  The Veterinary record 20110723

• Inhibitory mechanism of pure curcumin on Wilms' tumor 1 (WT1) gene expression through the PKCα signaling pathway in leukemic K562 cells.

  FEBS letters 20110721

• Transient complete atrioventricular block associated with curcumin intake.

  International journal of cardiology 20110715

• Curcumin ameliorates oxaliplatin-induced chemoresistance in HCT116 colorectal cancer cells in vitro and in vivo.

  International journal of cancer 20110715

• Curcumin attenuates allergic airway inflammation and hyper-responsiveness in mice through NF-κB inhibition.

  Journal of ethnopharmacology 20110714

• Molecular evidences for the chemosensitizing efficacy of liposomal curcumin in paclitaxel chemotherapy in mouse models of cervical cancer.

  Oncogene 20110714

• Targeting colon cancer stem cells using a new curcumin analogue, GO-Y030.

  British journal of cancer 20110712

• A comparative study of curcuminoids to measure their effect on inflammatory and apoptotic gene expression in an Aβ plus ibotenic acid-infused rat model of Alzheimer's disease.

  Brain research 20110711

• Curcumin induced nanoscale CD44 molecular redistribution and antigen-antibody interaction on HepG2 cell surface.

  Analytica chimica acta 20110704

• Curcumin improves insulin resistance in skeletal muscle of rats.

  Nutrition, metabolism, and cardiovascular diseases : NMCD 20110701

• Protective effect of curcumin on experimentally induced inflammation, hepatotoxicity and cardiotoxicity in rats: evidence of its antioxidant property.

  Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20110701

• Inhibitory effect of curcumin on uterine leiomyoma cell proliferation.

  Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20110701

• Curcumin decreases cholangiocarcinogenesis in hamsters by suppressing inflammation-mediated molecular events related to multistep carcinogenesis.

  International journal of cancer 20110701

• A phase I/II study of gemcitabine-based chemotherapy plus curcumin for patients with gemcitabine-resistant pancreatic cancer.

  Cancer chemotherapy and pharmacology 20110701

• Curcuminoids rescue long-term potentiation impaired by amyloid peptide in rat hippocampal slices.

  Synapse (New York, N.Y.) 20110701

• A novel solubility-enhanced curcumin formulation showing stability and maintenance of anticancer activity.

  Journal of pharmaceutical sciences 20110701

• Roles of the ERK, JNK/AP-1/cyclin D1-CDK4 pathway in silica-induced cell cycle changes in human embryo lung fibroblast cells.

  Cell biology international 20110701

• Effects of curcumin on the dorsal root ganglion structure and functional recovery after sciatic nerve crush in rat.

  Micron (Oxford, England : 1993) 20110701

• Attenuation of hematoma size and neurological injury with curcumin following intracerebral hemorrhage in mice.

  Journal of neurosurgery 20110701

• Curcumin could prevent methemoglobinemia induced by dapsone in rats.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110701

• Curcumin and genistein additively potentiate G551D-CFTR.

  Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society 20110701

• Curcumin disrupts uterine leiomyosarcoma cells through AKT-mTOR pathway inhibition.

  Gynecologic oncology 20110701

• Adaptogenic potential of curcumin in experimental chronic stress and chronic unpredictable stress-induced memory deficits and alterations in functional homeostasis.

  Journal of natural medicines 20110701

• Curcumin for clinical and endoscopic remission in ulcerative colitis.

  Inflammatory bowel diseases 20110701

• Conjugation of curcumin onto hyaluronic acid enhances its aqueous solubility and stability.

  Journal of colloid and interface science 20110701

• Curcumin inhibits skin squamous cell carcinoma tumor growth in vivo.

  Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 20110701

• Synergistic effect of curcumin and cisplatin via down-regulation of thymidine phosphorylase and excision repair cross-complementary 1 (ERCC1).

  Molecular pharmacology 20110701

• Dual effects of curcumin on neuronal oxidative stress in the presence of Cu(II).

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110701

• Gastroprotective and antidepressant effects of a new zinc(II)-curcumin complex in rodent models of gastric ulcer and depression induced by stresses.

  Pharmacology, biochemistry, and behavior 20110701

• Curcumin analogues as possible anti-proliferative & anti-inflammatory agents.

  European journal of medicinal chemistry 20110701

• CRM1-dependent p53 nuclear accumulation in lung lesions of a bitransgenic mouse lung tumor model.

  Oncology reports 20110701

• SREBP2 mediates the modulation of intestinal NPC1L1 expression by curcumin.

  American journal of physiology. Gastrointestinal and liver physiology 20110701

• Curcumin attenuates the expression and secretion of RANTES after spinal cord injury in vivo and lipopolysaccharide-induced astrocyte reactivation in vitro.

  Journal of neurotrauma 20110701

• Curcumin reduces pulmonary tumorigenesis in vascular endothelial growth factor (VEGF)-overexpressing transgenic mice.

  Molecular nutrition & food research 20110701

• Hepatoprotective effect of curcumin in lipopolysaccharide/-galactosamine model of liver injury in rats: relationship to HO-1/CO antioxidant system.

  Fitoterapia 20110701

• Highly loaded, sustained-release microparticles of curcumin for chemoprevention.

  Journal of pharmaceutical sciences 20110701

• Curcumin attenuates hyperglycaemia-mediated AMPK activation and oxidative stress in cerebrum of streptozotocin-induced diabetic rat.

  Free radical research 20110701

• Curcumin sensitizes acute promyelocytic leukemia cells to unfolded protein response-induced apoptosis by blocking the loss of misfolded N-CoR protein.

  Molecular cancer research : MCR 20110701

• Effect of silymarin on curcumin-induced mortality in zebrafish (Danio rerio) embryos and larvae.

  Indian journal of experimental biology 20110701

• Design, synthesis and destructive dynamic effects of BODIPY-containing and curcuminoid boron tracedrugs for neutron dynamic therapy.

  Anticancer research 20110701

• Structure of modified ε-polylysine micelles and their application in improving cellular antioxidant activity of curcuminoids.

  Food & function 20110701

• Polyphenols and human health: a prospectus.

  Critical reviews in food science and nutrition 20110701

• Sesquarterpenes (C35 terpenes) biosynthesized via the cyclization of a linear C35 isoprenoid by a tetraprenyl-β-curcumene synthase and a tetraprenyl-β-curcumene cyclase: identification of a new terpene cyclase.

  Journal of the American Chemical Society 20110629

• 1,2,3,4,6-penta-O-galloyl-β-D-glucose, quercetin, curcumin and lycopene induce cell-cycle arrest in MDA-MB-231 and BT474 cells through downregulation of Skp2 protein.

  Journal of agricultural and food chemistry 20110622

• In vivo detection of amyloid β deposition using ¹⁹F magnetic resonance imaging with a ¹⁹F-containing curcumin derivative in a mouse model of Alzheimer's disease.

  Neuroscience 20110616

• Modulation of pentylenetetrazole-induced kindling and oxidative stress by curcumin in mice.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20110615

• Proteomic identification of differentially expressed proteins in curcumin-treated MCF-7 cells.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20110615

• Synthesis of substituted triazolyl curcumin mimics that inhibit RANKL-induced osteoclastogenesis.

  Bioorganic & medicinal chemistry letters 20110615

• Significant enhancement in radical-scavenging activity of curcuminoids conferred by acetoxy substituent at the central methylene carbon.

  Bioorganic & medicinal chemistry 20110615

• Curcumin enhanced adriamycin-induced human liver-derived Hepatoma G2 cell death through activation of mitochondria-mediated apoptosis and autophagy.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20110614

• A novel monocarbonyl analogue of curcumin, (1E,4E)-1,5-bis(2,3-dimethoxyphenyl)penta-1,4-dien-3-one, induced cancer cell H460 apoptosis via activation of endoplasmic reticulum stress signaling pathway.

  Journal of medicinal chemistry 20110609

• Resveratrol in combination with other dietary polyphenols concomitantly enhances antiproliferation and UGT1A1 induction in Caco-2 cells.

  Life sciences 20110606

• Curcumin: an anti-inflammatory molecule from a curry spice on the path to cancer treatment.

  Molecules (Basel, Switzerland) 20110603

• Induction of human fetal hemoglobin via the NRF2 antioxidant response signaling pathway.

  Blood 20110602

• Topical curcumin can inhibit deleterious effects of upper respiratory tract bacteria on human oropharyngeal cells in vitro: potential role for patients with cancer therapy induced mucositis?

  Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20110601

• Curcumin regulates miR-21 expression and inhibits invasion and metastasis in colorectal cancer.

  Bioscience reports 20110601

• Curcumin enhances neuronal survival in N-methyl-d-aspartic acid toxicity by inducing RANTES expression in astrocytes via PI-3K and MAPK signaling pathways.

  Progress in neuro-psychopharmacology & biological psychiatry 20110601

• Antioxidative effects of curcumin, β-myrcene and 1,8-cineole against 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced oxidative stress in rats liver.

  Toxicology and industrial health 20110601

• Comparative protective action of curcumin, memantine and diclofenac against scopolamine-induced memory dysfunction.

  Fitoterapia 20110601

• Regulation of hemocytes in Drosophila requires dappled cytochrome b5.

  Biochemical genetics 20110601

• The combined effects of exercise and foods in preventing neurological and cognitive disorders.

  Preventive medicine 20110601

• Interpretation of the effects of protein kinase C inhibitors on human UDP-glucuronosyltransferase 1A (UGT1A) proteins in cellulo.

  Drug metabolism and pharmacokinetics 20110601

• Polyphenols: planting the seeds of treatment for the metabolic syndrome.

  Nutrition (Burbank, Los Angeles County, Calif.) 20110601

• Cytometric analysis on cytotoxicity of curcumin on rat thymocytes: Proapoptotic and antiapoptotic actions of curcumin.

  Toxicology in vitro : an international journal published in association with BIBRA 20110601

• Two solutions in search of a problem.

  Hepatology (Baltimore, Md.) 20110601

• Curcumin attenuates staurosporine-mediated death of retinal ganglion cells.

  Investigative ophthalmology & visual science 20110601

• Kinase gene expression and subcellular protein expression pattern of protein kinase C isoforms in curcumin-treated human hepatocellular carcinoma Hep 3B cells.

  Plant foods for human nutrition (Dordrecht, Netherlands) 20110601

• Gastroesophageal reflux disease (GERD): a review of conventional and alternative treatments.

  Alternative medicine review : a journal of clinical therapeutic 20110601

• Curcumin for inflammatory bowel disease: a review of human studies.

  Alternative medicine review : a journal of clinical therapeutic 20110601

• Towards a pharmacophore for amyloid.

  PLoS biology 20110601

• [Effect of curcumin in combination with bortezomib on proliferation and apoptosis of human multiple myeloma cell line H929 and its mechanism].

  Zhongguo shi yan xue ye xue za zhi 20110601

• Curcumin suppresses the production of interleukin-6 in Prevotella intermedia lipopolysaccharide-activated RAW 264.7 cells.

  Journal of periodontal & implant science 20110601

• Curcumin-loaded lipid and polymeric nanocapsules stabilized by nonionic surfactants: an in vitro and In vivo antitumor activity on B16-F10 melanoma and macrophage uptake comparative study.

  Journal of biomedical nanotechnology 20110601

• [Bioactivity and action modes of bisdemethoxycurcumin against Tetranychus cinnabarinus Bois. (Acari:Tetranychidae)].

  Ying yong sheng tai xue bao = The journal of applied ecology 20110601

• [The effects of curcumin derivative on experimental steatohepatitis].

  Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20110601

• [Chemoprevention of prostate cancer].

  Nihon rinsho. Japanese journal of clinical medicine 20110601

• Suppression of phorbol-12-myristate-13-acetate-induced tumor cell invasion by piperine via the inhibition of PKCα/ERK1/2-dependent matrix metalloproteinase-9 expression.

  Toxicology letters 20110530

• [Effect of curcumin on the expression of high mobility group box 1 and apoptotic neurons in hippocampus after global cerebral ischemia reperfusion in rats].

  Zhonghua yi xue za zhi 20110524

• Design, synthesis and evaluation of novel PEGylated curcumin analogs as potent Nrf2 activators in human bronchial epithelial cells.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20110518

• Genotoxicity and apoptosis in Drosophila melanogaster exposed to benzene, toluene and xylene: attenuation by quercetin and curcumin.

  Toxicology and applied pharmacology 20110515

• Epigenetic regulation of high glucose-induced proinflammatory cytokine production in monocytes by curcumin.

  The Journal of nutritional biochemistry 20110501

• Natural products as DNA methyltransferase inhibitors: a computer-aided discovery approach.

  Molecular diversity 20110501

• Suppression of fatty acid synthase, differentiation and lipid accumulation in adipocytes by curcumin.

  Molecular and cellular biochemistry 20110501

• Curcumin protects against A53T alpha-synuclein-induced toxicity in a PC12 inducible cell model for Parkinsonism.

  Pharmacological research 20110501

• Curcumin induces a nuclear factor-erythroid 2-related factor 2-driven response against oxidative and nitrative stress after praziquantel treatment in liver fluke-infected hamsters.

  International journal for parasitology 20110501

• Curcumin analog GO-Y030 is a novel inhibitor of IKKβ that suppresses NF-κB signaling and induces apoptosis.

  Cancer science 20110501

• Curcumin potentiates doxorubicin-induced apoptosis in H9c2 cardiac muscle cells through generation of reactive oxygen species.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110501

• The antihyperglycemic effect of curcumin in high fat diet fed rats. Role of TNF-α and free fatty acids.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110501

• Development and in vitro-in vivo evaluation of polymeric implants for continuous systemic delivery of curcumin.

  Pharmaceutical research 20110501

• Brain and spinal cord interaction: a dietary curcumin derivative counteracts locomotor and cognitive deficits after brain trauma.

  Neurorehabilitation and neural repair 20110501

• Curcumin inhibits cystogenesis by simultaneous interference of multiple signaling pathways: in vivo evidence from a Pkd1-deletion model.

  American journal of physiology. Renal physiology 20110501

• Novel role of curcumin combined with bone marrow transplantation in reversing experimental diabetes: Effects on pancreatic islet regeneration, oxidative stress, and inflammatory cytokines.

  European journal of pharmacology 20110501

• Bioavailability enhancement of curcumin by complexation with phosphatidyl choline.

  Journal of pharmaceutical sciences 20110501

• Ferrocenyl-substituted curcumin: can it influence antioxidant ability to protect DNA?

  European journal of medicinal chemistry 20110501

• Curcumin inhibition of the functional interaction between integrin α6β4 and the epidermal growth factor receptor.

  Molecular cancer therapeutics 20110501

• Role of curcumin-dependent modulation of tumor microenvironment of a murine T cell lymphoma in altered regulation of tumor cell survival.

  Toxicology and applied pharmacology 20110501

• Antioxidant and vascular protective effects of curcumin and tetrahydrocurcumin in rats with L-NAME-induced hypertension.

  Naunyn-Schmiedeberg's archives of pharmacology 20110501

• Effects of oral curcumin on the pharmacokinetics of intravenous and oral etoposide in rats: possible role of intestinal CYP3A and P-gp inhibition by curcumin.

  Biopharmaceutics & drug disposition 20110501

• Sensitization of head and neck cancer to cisplatin through the use of a novel curcumin analog.

  Archives of otolaryngology--head & neck surgery 20110501

• [Proteomic research on anti-atherosclerosis mechanism of curcumin in RAW264.7].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110501

• Mucoadhesive curcumin nanospheres: biological activity, adhesion to stomach mucosa and release of curcumin into the circulation.

  Journal of controlled release : official journal of the Controlled Release Society 20110430

• Comparative absorption of a standardized curcuminoid mixture and its lecithin formulation.

  Journal of natural products 20110425

• Curcumin blocks interleukin (IL)-2 signaling in T-lymphocytes by inhibiting IL-2 synthesis, CD25 expression, and IL-2 receptor signaling.

  Biochemical and biophysical research communications 20110422

• Curcumin activates Wnt/β-catenin signaling pathway through inhibiting the activity of GSK-3β in APPswe transfected SY5Y cells.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20110418

• Curcumin reverses corticosterone-induced depressive-like behavior and decrease in brain BDNF levels in rats.

  Neuroscience letters 20110415

• Amyloid-binding compounds maintain protein homeostasis during ageing and extend lifespan.

  Nature 20110414

• Interaction of curcumin and bixin with β-cyclodextrin: complexation methods, stability, and applications in food.

  Journal of agricultural and food chemistry 20110413

• Catalytic asymmetric Michael addition with curcumin derivative.

  Organic & biomolecular chemistry 20110407

• Curcumin provides neuroprotection after spinal cord injury.

  The Journal of surgical research 20110401

• Curcumin nanodisks: formulation and characterization.

  Nanomedicine : nanotechnology, biology, and medicine 20110401

• Role of alpha class glutathione transferases (GSTs) in chemoprevention: GSTA1 and A4 overexpressing human leukemia (HL60) cells resist sulforaphane and curcumin induced toxicity.

  Phytotherapy research : PTR 20110401

• Effects of curcumin (diferuloylmethane) on Eimeria tenella sporozoites in vitro.

  Parasitology research 20110401

• Curcuma as a parasiticidal agent: a review.

  Planta medica 20110401

• Suppression of mitochondrial NADP(+)-dependent isocitrate dehydrogenase activity enhances curcumin-induced apoptosis in HCT116 cells.

  Free radical research 20110401

• Difluorinated-curcumin (CDF): a novel curcumin analog is a potent inhibitor of colon cancer stem-like cells.

  Pharmaceutical research 20110401

• Curcumin-induced inhibition of proteasomal activity, enhanced HSP accumulation and the acquisition of thermotolerance in Xenopus laevis A6 cells.

  Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20110401

• Interaction of a curcumin analogue dimethoxycurcumin with DNA.

  Chemical biology & drug design 20110401

• Curcumin-loaded biodegradable polymeric micelles for colon cancer therapy in vitro and in vivo.

  Nanoscale 20110401

• Potent anti-inflammatory effects of systemically administered curcumin modulate periodontal disease in vivo.

  Journal of periodontal research 20110401

• Inhibitory effect of curcumin on oral carcinoma CAL-27 cells via suppression of Notch-1 and NF-κB signaling pathways.

  Journal of cellular biochemistry 20110401

• Curcumin prevents experimental diabetic retinopathy in rats through its hypoglycemic, antioxidant, and anti-inflammatory mechanisms.

  Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20110401

• Feruloylacetone as the model compound of half-curcumin: synthesis and antioxidant properties.

  European journal of medicinal chemistry 20110401

• Curcumin delivery by methoxy polyethylene glycol-poly(caprolactone) nanoparticles inhibits the growth of C6 glioma cells.

  Acta biochimica et biophysica Sinica 20110401

• New mechanisms and the anti-inflammatory role of curcumin in obesity and obesity-related metabolic diseases.

  European journal of nutrition 20110401

• Synergism from sequenced combinations of curcumin and epigallocatechin-3-gallate with cisplatin in the killing of human ovarian cancer cells.

  Anticancer research 20110401

• Attenuation of fatty liver and prevention of hypercholesterolemia by extract of Curcuma longa through regulating the expression of CYP7A1, LDL-receptor, HO-1, and HMG-CoA reductase.

  Journal of food science 20110401

• Antilithogenic influence of dietary capsaicin and curcumin during experimental induction of cholesterol gallstone in mice.

  Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 20110401

• [Effect of curcumin on expression of Abeta42 and Abeta-degrading enzyme NEP in APPswe/PS1dE9 double transgenic mice].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110401

• Food: The omnivore's labyrinth.

  Nature 20110324

• Curcumin regulates low-linear energy transfer γ-radiation-induced NFκB-dependent telomerase activity in human neuroblastoma cells.

  International journal of radiation oncology, biology, physics 20110315

• Curcumin nanoparticles: preparation, characterization, and antimicrobial study.

  Journal of agricultural and food chemistry 20110309

• Translational research in pancreatic cancer. Highlights from the '2011 ASCO Gastrointestinal Cancers Symposium'. San Francisco, CA, USA. January 20-22, 2011.

  JOP : Journal of the pancreas 20110309

• Differential protection of pre-, co- and post-treatment of curcumin against hydrogen peroxide in PC12 cells.

  Human & experimental toxicology 20110301

• Ultrasound-induced cell death of nasopharyngeal carcinoma cells in the presence of curcumin.

  Integrative cancer therapies 20110301

• Curcumin has bright prospects for the treatment of multiple sclerosis.

  International immunopharmacology 20110301

• Immunomodulatory and therapeutic activity of curcumin.

  International immunopharmacology 20110301

• Akt is upstream and MAPKs are downstream of NF-κB in paclitaxel-induced survival signaling events, which are down-regulated by curcumin contributing to their synergism.

  The international journal of biochemistry & cell biology 20110301

• Curcumin induces heme oxygenase-1 in normal human skin fibroblasts through redox signaling: relevance for anti-aging intervention.

  Molecular nutrition & food research 20110301

• Exploring solid lipid nanoparticles to enhance the oral bioavailability of curcumin.

  Molecular nutrition & food research 20110301

• Studies on curcumin and curcuminoids. XXXIX. Photophysical properties of bisdemethoxycurcumin.

  Journal of fluorescence 20110301

• The targets of curcumin.

  Current drug targets 20110301

• Reactions of reactive oxygen species (ROS) with curcumin analogues: Structure-activity relationship.

  Free radical research 20110301

• Development and evaluation of vesicular system for curcumin delivery.

  Archives of dermatological research 20110301

• Affinity interactions between natural pigments and human whole saliva.

  Archives of oral biology 20110301

• Controlled release of oral tetrahydrocurcumin from a novel self-emulsifying floating drug delivery system (SEFDDS).

  AAPS PharmSciTech 20110301

• Curcumin inhibits renal cyst formation and enlargement in vitro by regulating intracellular signaling pathways.

  European journal of pharmacology 20110301

• A polymeric nanoparticle formulation of curcumin inhibits growth, clonogenicity and stem-like fraction in malignant brain tumors.

  Cancer biology & therapy 20110301

• Anti-proliferative potential of curcumin in androgen-dependent prostate cancer cells occurs through modulation of the Wingless signaling pathway.

  International journal of oncology 20110301

• Indian gold treating cancer in the age of nano.

  Cancer biology & therapy 20110301

• Enhancement of pancreatic lipase inhibitory activity of curcumin by radiolytic transformation.

  Bioorganic & medicinal chemistry letters 20110301

• Targeting sarcoplasmic/endoplasmic reticulum Ca²+-ATPase 2 by curcumin induces ER stress-associated apoptosis for treating human liposarcoma.

  Molecular cancer therapeutics 20110301

• Use of curcumin to decrease nitric oxide production during the induction of antitumor responses by IL-2.

  Journal of immunotherapy (Hagerstown, Md. : 1997) 20110301

• A simplified and high-throughput chromogenic assay for testing tissue factor-dependent procoagulant activity.

  Journal of biomolecular screening 20110301

• Upregulation of p53 expression in patients with colorectal cancer by administration of curcumin.

  Cancer investigation 20110301

• Curcumin prevents DNA damage and enhances the repair potential in a chronically arsenic-exposed human population in West Bengal, India.

  European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 20110301

• Curcumin as a promising anticandidal of clinical interest.

  Canadian journal of microbiology 20110301

• Clinical Inquiry. Does turmeric relieve inflammatory conditions?

  The Journal of family practice 20110301

• Curcumin chemoprevention: the long road to clinical translation.

  Cancer prevention research (Philadelphia, Pa.) 20110301

• Phase IIa clinical trial of curcumin for the prevention of colorectal neoplasia.

  Cancer prevention research (Philadelphia, Pa.) 20110301

• Exercise training and antioxidants: effects on rat heart tissue exposed to lead acetate.

  International journal of toxicology 20110301

• Antioxidative effects of N-acetylcysteine, lipoic acid, taurine, and curcumin in the muscle of Cyprinus carpio L. exposed to cadmium.

  Arhiv za higijenu rada i toksikologiju 20110301

• [Effect of curcumin on the learning, memory and hippocampal Ca+/CaMK II level in senescence-accelerated mice].

  Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20110301

• Differential distribution of intravenous curcumin formulations in the rat brain.

  Anticancer research 20110301

• Curcumin protects against NMDA-induced toxicity: a possible role for NR2A subunit.

  Investigative ophthalmology & visual science 20110222

• Synthesis, characterization and biological evaluation of succinate prodrugs of curcuminoids for colon cancer treatment.

  Molecules (Basel, Switzerland) 20110222

• Curcumin as the OO bidentate ligand in '2 + 1' complexes with the [M(CO)3]+ (M = Re, 99mTc) tricarbonyl core for radiodiagnostic applications.

  Inorganic chemistry 20110221

• Curcumin diminishes the impacts of hyperglycemia on the activation of hepatic stellate cells by suppressing membrane translocation and gene expression of glucose transporter-2.

  Molecular and cellular endocrinology 20110220

• Curcumin enhances dasatinib-induced inhibition of growth and transformation of colon cancer cells.

  International journal of cancer 20110215

• Differential glucocorticoid receptor-mediated transcription mechanisms.

  The Journal of biological chemistry 20110211

• Curcumin I protects the dopaminergic cell line SH-SY5Y from 6-hydroxydopamine-induced neurotoxicity through attenuation of p53-mediated apoptosis.

  Neuroscience letters 20110211

• Anti-angiogenic effect of resveratrol or curcumin in Ehrlich ascites carcinoma-bearing mice.

  European journal of pharmacology 20110210

• The effects of a synthetic curcuminoid analogue, 2,6-bis-(4-hydroxyl-3-methoxybenzylidine)cyclohexanone on proinflammatory signaling pathways and CLP-induced lethal sepsis in mice.

  European journal of pharmacology 20110210

• Cooperative binding and stabilization of the medicinal pigment curcumin by diamide linked γ-cyclodextrin dimers: a spectroscopic characterization.

  The journal of physical chemistry. B 20110210

• Modification of curcumin with polyethylene glycol enhances the delivery of curcumin in preadipocytes and its antiadipogenic property.

  Journal of agricultural and food chemistry 20110209

• Mechanisms for the activity of heterocyclic cyclohexanone curcumin derivatives in estrogen receptor negative human breast cancer cell lines.

  Investigational new drugs 20110201

• Encapsulation of curcumin in Pluronic block copolymer micelles for drug delivery applications.

  Journal of biomaterials applications 20110201

• Regulation of expression of antioxidant enzymes by vitamin E and curcumin in L-thyroxine-induced oxidative stress in rat renal cortex.

  Molecular biology reports 20110201

• Modulation of neutrophil motility by curcumin: implications for inflammatory bowel disease.

  Inflammatory bowel diseases 20110201

• Optimization and formulation design of gels of Diclofenac and Curcumin for transdermal drug delivery by Box-Behnken statistical design.

  Journal of pharmaceutical sciences 20110201

• Ultrasound induces cellular destruction of nasopharyngeal carcinoma cells in the presence of curcumin.

  Ultrasonics 20110201

• Density functional theory investigation of Cu(I)- and Cu(II)-curcumin complexes.

  Journal of computational chemistry 20110201

• Coffee, broccoli and spices are strong inducers of electrophile response element-dependent transcription in vitro and in vivo - studies in electrophile response element transgenic mice.

  Molecular nutrition & food research 20110201

• Chemopreventive effect of dietary curcumin on inflammation-induced colorectal carcinogenesis in mice.

  Molecular nutrition & food research 20110201

• Synthesis and characterization of a cytotoxic cationic polyvinylpyrrolidone-curcumin conjugate.

  Journal of pharmaceutical sciences 20110201

• Preparation and characterization of intravenously injectable curcumin nanosuspension.

  Drug delivery 20110201

• Curcumin's effect on intestinal inflammation and tumorigenesis in the ApcMin/+ mouse.

  Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20110201

• Swellable hydrogel particles for controlled release pulmonary administration using propellant-driven metered dose inhalers.

  Journal of aerosol medicine and pulmonary drug delivery 20110201

• NFκB inhibitors induce cell death in glioblastomas.

  Biochemical pharmacology 20110201

• Curcumin-loaded PLGA-PEG-PLGA triblock copolymeric micelles: Preparation, pharmacokinetics and distribution in vivo.

  Journal of colloid and interface science 20110201

• Hollow microcapsules built by layer by layer assembly for the encapsulation and sustained release of curcumin.

  Colloids and surfaces. B, Biointerfaces 20110201

• Curcumin promotes degradation of inducible nitric oxide synthase and suppresses its enzyme activity in RAW 264.7 cells.

  International immunopharmacology 20110201

• Curcumin-decorated nanoliposomes with very high affinity for amyloid-β1-42 peptide.

  Biomaterials 20110201

• Testosterone augments polyphenol-induced DNA damage response in prostate cancer cell line, LNCaP.

  Cancer science 20110201

• Bisdemethoxycurcumin protects endothelial cells against t-BHP-induced cell damage by regulating the phosphorylation level of ERK1/2 and Akt.

  International journal of molecular medicine 20110201

• Modulation of anxiety behavior by intranasally administered vaccinia virus complement control protein and curcumin in a mouse model of Alzheimer's disease.

  Current Alzheimer research 20110201

• Identification of permeability-related hurdles in oral delivery of curcumin using the Caco-2 cell model.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20110201

• Synthesis and preliminary evaluation of curcumin analogues as cytotoxic agents.

  Bioorganic & medicinal chemistry letters 20110201

• Identification of curcumin derivatives as human glyoxalase I inhibitors: A combination of biological evaluation, molecular docking, 3D-QSAR and molecular dynamics simulation studies.

  Bioorganic & medicinal chemistry 20110201

• In vitro inhibitory effect of tetrahydrocurcuminoids on Fusarium proliferatum growth and fumonisin B₁ biosynthesis.

  Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20110201

• Nutraceuticals for the treatment of osteoarthritis.

  Minerva medica 20110201

• Can curcumin provide an ideal contraceptive?

  Molecular reproduction and development 20110201

• [Anti-proliferative and anti-metastatic effects of curcumin on oral cancer cells].

  Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology 20110201

• Regulation of the expression of cyclooxygenases and production of prostaglandin I₂ and E₂ in human coronary artery endothelial cells by curcumin.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20110201

• Preparation and characterization of lyophilised egg PC liposomes incorporating curcumin and evaluation of its activity against colorectal cancer cell lines.

  Journal of nanoscience and nanotechnology 20110201

• Investigations on the interaction of gold-curcumin nanoparticles with human peripheral blood lymphocytes.

  Journal of biomedical nanotechnology 20110201

• Effects of curcumin on lung histopathology and fungal burden in a mouse model of chronic asthma and oropharyngeal candidiasis.

  Archives of medical research 20110201

• Antileishmanial activity of nanocurcumin.

  Therapeutic delivery 20110201

• Inhibitors of microglial neurotoxicity: focus on natural products.

  Molecules (Basel, Switzerland) 20110125

• Surface functionalization of PLGA nanoparticles by non-covalent insertion of a homo-bifunctional spacer for active targeting in cancer therapy.

  Nanotechnology 20110121

• Curcumin and Alzheimer disease: this marriage is not to be performed.

  The Journal of biological chemistry 20110121

• Preparation and characterization of water-soluble albumin-bound curcumin nanoparticles with improved antitumor activity.

  International journal of pharmaceutics 20110117

• Curcumin improves bone microarchitecture and enhances mineral density in APP/PS1 transgenic mice.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20110115

• Inhibition of tumor growth and vasculogenic mimicry by curcumin through down-regulation of the EphA2/PI3K/MMP pathway in a murine choroidal melanoma model.

  Cancer biology & therapy 20110115

• Chemo-resistant melanoma sensitized by tamoxifen to low dose curcumin treatment through induction of apoptosis and autophagy.

  Cancer biology & therapy 20110115

• 2-Hydroxycurcuminoid induces apoptosis of human tumor cells through the reactive oxygen species-mitochondria pathway.

  Bioorganic & medicinal chemistry letters 20110115

• Curcumin: a component of the golden spice, targets multiple angiogenic pathways.

  Cancer biology & therapy 20110115

• Autoxidative and cyclooxygenase-2 catalyzed transformation of the dietary chemopreventive agent curcumin.

  The Journal of biological chemistry 20110114

• Neuroprotective effects of curcumin on 6-hydroxydopamine-induced Parkinsonism in rats: behavioral, neurochemical and immunohistochemical studies.

  Brain research 20110112

• Curcumin induced HepG2 cell apoptosis-associated mitochondrial membrane potential and intracellular free Ca(2+) concentration.

  European journal of pharmacology 20110110

• Downregulation of B lymphocyte stimulator expression by curcumin in B lymphocyte via suppressing nuclear translocation of NF-κB.

  European journal of pharmacology 20110110

• Nitrosative stress-induced Parkinsonian Lewy-like aggregates prevented through polyphenolic phytochemical analog intervention.

  Biochemical and biophysical research communications 20110107

• Tetrahydrocurcumin confers protection against amyloid β-induced toxicity.

  Neuroreport 20110105

• Curcumin does not bind or intercalate into DNA and a note on the gray side of curcumin.

  International journal of cancer 20110101

• More research is needed to establish the benefit-risk profile of curcumin.

  International journal of cancer 20110101

• Involvement of nucleophosmin/B23 in the cellular response to curcumin.

  The Journal of nutritional biochemistry 20110101

• Contact urticaria to cosmetic and industrial dyes.

  Clinical and experimental dermatology 20110101

• Identification of amyloid plaques in retinas from Alzheimer's patients and noninvasive in vivo optical imaging of retinal plaques in a mouse model.

  NeuroImage 20110101

• Formulation and bacterial phototoxicity of curcumin loaded alginate foams for wound treatment applications: studies on curcumin and curcuminoides XLII.

  Journal of pharmaceutical sciences 20110101

• Determination of protein by fluorescence enhancement of curcumin in lanthanum-curcumin-sodium dodecyl benzene sulfonate-protein system.

  Journal of fluorescence 20110101

• Role of curcumin in the prevention of cholinergic mediated cortical dysfunctions in streptozotocin-induced diabetic rats.

  Molecular and cellular endocrinology 20110101

• Self-microemulsifying drug delivery system improves curcumin dissolution and bioavailability.

  Drug development and industrial pharmacy 20110101

• Terpene microemulsions for transdermal curcumin delivery: effects of terpenes and cosurfactants.

  Colloids and surfaces. B, Biointerfaces 20110101

• Apolipoprotein E LDL receptor-binding domain-containing high-density lipoprotein: a nanovehicle to transport curcumin, an antioxidant and anti-amyloid bioflavonoid.

  Biochimica et biophysica acta 20110101

• Curcumin attenuates peroxynitrite-induced neurotoxicity in spiral ganglion neurons.

  Neurotoxicology 20110101

• Curcumin is a lipid dependent inhibitor of the Na,K-ATPase that likely interacts at the protein-lipid interface.

  Biochimica et biophysica acta 20110101

• Neuroprotective and neurorescue effects of a novel polymeric nanoparticle formulation of curcumin (NanoCurc™) in the neuronal cell culture and animal model: implications for Alzheimer's disease.

  Journal of Alzheimer's disease : JAD 20110101

• Water-dispersible multifunctional hybrid nanogels for combined curcumin and photothermal therapy.

  Biomaterials 20110101

• Mutant hypoxia inducible factor-1α improves angiogenesis and tissue perfusion in ischemic rabbit skeletal muscle.

  Microvascular research 20110101

• Curcumin counteracts the proliferative effect of estradiol and induces apoptosis in cervical cancer cells.

  Molecular and cellular biochemistry 20110101

• Curcumin dually inhibits both mammalian target of rapamycin and nuclear factor-κB pathways through a crossed phosphatidylinositol 3-kinase/Akt/IκB kinase complex signaling axis in adenoid cystic carcinoma.

  Molecular pharmacology 20110101

• Glutamoyl diester of the dietary polyphenol curcumin offers improved protection against peroxynitrite-mediated nitrosative stress and damage of brain mitochondria in vitro: implications for Parkinson's disease.

  Molecular and cellular biochemistry 20110101

• Delayed treatment with a novel neurotrophic compound reduces behavioral deficits in rabbit ischemic stroke.

  Journal of neurochemistry 20110101

• β-dicarbonyl enolates: a new class of neuroprotectants.

  Journal of neurochemistry 20110101

• Initial observations of cell-mediated drug delivery to the deep lung.

  Cell transplantation 20110101

• Curcumin suppresses human papillomavirus oncoproteins, restores p53, Rb, and PTPN13 proteins and inhibits benzo[a]pyrene-induced upregulation of HPV E7.

  Molecular carcinogenesis 20110101

• Inhibitory effect of curcumin on angiogenesis in ectopic endometrium of rats with experimental endometriosis.

  International journal of molecular medicine 20110101

• Curcumin induces paraoxonase 1 in cultured hepatocytes in vitro but not in mouse liver in vivo.

  The British journal of nutrition 20110101

• Curcumin reduces injury progression in a rat comb burn model.

  Journal of burn care & research : official publication of the American Burn Association 20110101

• Suppression of keloid fibroblast.

  Archives of dermatological research 20110101

• Two small molecule compounds, LLL12 and FLLL32, exhibit potent inhibitory activity on STAT3 in human rhabdomyosarcoma cells.

  International journal of oncology 20110101

• Neuroprotective and neurotrophic curcuminoids to treat stroke: a translational perspective.

  Expert opinion on investigational drugs 20110101

• Dietary factors and pancreatic cancer: the role of food bioactive compounds.

  Molecular nutrition & food research 20110101

• Reversal of cardiac iron loading and dysfunction in thalassemic mice by curcuminoids.

  Medicinal chemistry (Shariqah (United Arab Emirates)) 20110101

• Protective effect of curcumin (Curcuma longa) against D-galactose-induced senescence in mice.

  Journal of Asian natural products research 20110101

• Synergistic apoptotic effect of arabinoxylan rice bran (MGN-3/Biobran) and curcumin (turmeric) on human multiple myeloma cell line U266 in vitro.

  Neoplasma 20110101

• Curcumin alleviates matrix metalloproteinase-3 and -9 activities during eradication of Helicobacter pylori infection in cultured cells and mice.

  PloS one 20110101

• Targeting cell signaling and apoptotic pathways by dietary agents: role in the prevention and treatment of cancer.

  Nutrition and cancer 20110101

• Development and characterization of eucalyptol microemulsions for topic delivery of curcumin.

  Chemical & pharmaceutical bulletin 20110101

• Curcumin: A review of anti-cancer properties and therapeutic activity in head and neck squamous cell carcinoma.

  Molecular cancer 20110101

• Antioxidative properties of curcumin in the protection of blood platelets against oxidative stress in vitro.

  Platelets 20110101

• Effect of curcumin on the modulation of αA- and αB-crystallin and heat shock protein 70 in selenium-induced cataractogenesis in Wistar rat pups.

  Molecular vision 20110101

• Maintenance therapy for B-chronic lymphocytic leukemia.

  Clinical advances in hematology & oncology : H&O 20110101

• Curcuminoid binds to amyloid-β1-42 oligomer and fibril.

  Journal of Alzheimer's disease : JAD 20110101

• In silico theoretical molecular modeling for Alzheimer's disease: the nicotine-curcumin paradigm in neuroprotection and neurotherapy.

  International journal of molecular sciences 20110101

• Antioxidant effects of curcumin in spinal cord injury in rats.

  Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES 20110101

• Inhibition of Ca2+-release-activated Ca2+ channel (CRAC) and K+ channels by curcumin in Jurkat-T cells.

  Journal of pharmacological sciences 20110101

• RNA binding protein CUGBP2/CELF2 mediates curcumin-induced mitotic catastrophe of pancreatic cancer cells.

  PloS one 20110101

• MGAT3 mRNA: a biomarker for prognosis and therapy of Alzheimer's disease by vitamin D and curcuminoids.

  Journal of Alzheimer's disease : JAD 20110101

• A screening of curcumin derivatives for antibacterial phototoxic effects studies on curcumin and curcuminoids. XLIII.

  Die Pharmazie 20110101

• Anti-tumor activity of a novel compound-CDF is mediated by regulating miR-21, miR-200, and PTEN in pancreatic cancer.

  PloS one 20110101

• The plant-based immunomodulator curcumin as a potential candidate for the development of an adjunctive therapy for cerebral malaria.

  Malaria journal 20110101

• Curcumin attenuates lipopolysaccharide-induced renal inflammation.

  Biological & pharmaceutical bulletin 20110101

• Nutritional interventions for cancer-induced cachexia.

  Current problems in cancer 20110101

• Dietary flavonoids as cancer prevention agents.

  Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews 20110101

• [Empirical study of reverse effect on mediated multidrug resistance of U-2OS/ADM cells with curcumin in vitro].

  Wei sheng yan jiu = Journal of hygiene research 20110101

• The novel curcumin analog FLLL32 decreases STAT3 DNA binding activity and expression, and induces apoptosis in osteosarcoma cell lines.

  BMC cancer 20110101

• Antioxidant properties of quercetin.

  Advances in experimental medicine and biology 20110101

• Antioxidant properties of select radiation mitigators based on semicarbazone and pyrazole derivatives of curcumin.

  Advances in experimental medicine and biology 20110101

• Does curcumin protect against renal dysfunction following reversible unilateral ureteric obstruction in the rat?

  European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes 20110101

• Hypomethylation effects of curcumin, demethoxycurcumin and bisdemethoxycurcumin on WIF-1 promoter in non-small cell lung cancer cell lines.

  Molecular medicine reports 20110101

• Inhibition of nuclear factor kappa-B signaling reduces growth in medulloblastoma in vivo.

  BMC cancer 20110101

• Curcumin-induced HDAC inhibition and attenuation of medulloblastoma growth in vitro and in vivo.

  BMC cancer 20110101

• [Preparation and in vitro release characteristics of curcumin in nanosuspensions].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110101

• A synergistic antiproliferation effect of curcumin and docosahexaenoic acid in SK-BR-3 breast cancer cells: unique signaling not explained by the effects of either compound alone.

  BMC cancer 20110101

• Investigation of the photodynamic effects of curcumin against Candida albicans.

  Photochemistry and photobiology 20110101

• Ornithine decarboxylase prevents dibenzoylmethane-induced apoptosis through repressing reactive oxygen species generation.

  Journal of biochemical and molecular toxicology 20110101

• Innovative preparation of curcumin for improved oral bioavailability.

  Biological & pharmaceutical bulletin 20110101

• Non-conjugated small molecule FRET for differentiating monomers from higher molecular weight amyloid beta species.

  PloS one 20110101

• Effect of curcumin on cisplatin- and oxaliplatin-induced oxidative stress in human embryonic kidney (HEK) 293 cells.

  Renal failure 20110101

• Curcumin reduces expression of Bcl-2, leading to apoptosis in daunorubicin-insensitive CD34+ acute myeloid leukemia cell lines and primary sorted CD34+ acute myeloid leukemia cells.

  Journal of translational medicine 20110101

• Synthesis of 86 species of 1,5-diaryl-3-oxo-1,4-pentadienes analogs of curcumin can yield a good lead in vivo.

  BMC pharmacology 20110101

• Gene-specific differential response to anti-apoptotic therapies in zebrafish models of ocular coloboma.

  Molecular vision 20110101

• Formulation of curcumin-loaded solid lipid nanoparticles produced by fatty acids coacervation technique.

  Journal of microencapsulation 20110101

• Anti-inflammatory effect of Curcuma longa (turmeric) on collagen-induced arthritis: an anatomico-radiological study.

  La Clinica terapeutica 20110101

• Curcumin ameliorates cardiac inflammation in rats with autoimmune myocarditis.

  Biological & pharmaceutical bulletin 20110101

• [Molecular and cellular mechanisms of curcumin action--beneficial effect on organism].

  Postepy biochemii 20110101

• A natural p300-specific histone acetyltransferase inhibitor, curcumin, in addition to angiotensin-converting enzyme inhibitor, exerts beneficial effects on left ventricular systolic function after myocardial infarction in rats.

  Circulation journal : official journal of the Japanese Circulation Society 20110101

• Rescue of photoreceptor degeneration by curcumin in transgenic rats with P23H rhodopsin mutation.

  PloS one 20110101

• Inhibitory effects of 1,3-bis-(2-substituted-phenyl)-propane-1,3-dione, β-diketone structural analogues of curcumin, on chemical-induced tumor promotion and inflammation in mouse skin.

  Food & function 20110101

• Enhanced oral bioavailability of curcumin via a solid lipid-based self-emulsifying drug delivery system using a spray-drying technique.

  Biological & pharmaceutical bulletin 20110101

• Activation of nuclear factor erythroid 2-related factor 2 cytoprotective signaling by curcumin protect primary spinal cord astrocytes against oxidative toxicity.

  Biological & pharmaceutical bulletin 20110101

• Microbial conversion of curcumin into colorless hydroderivatives by the endophytic fungus Diaporthe sp. associated with Curcuma longa.

  Chemical & pharmaceutical bulletin 20110101

• [Comparative study on pharmacokinetics of curcumin extract of rhizoma curcumae longae and rhizoma wenyujin concisum in rats].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20110101

• Eudragit® S100 coated calcium pectinate microspheres of curcumin for colon targeting.

  Journal of microencapsulation 20110101

• No protective effect of curcumin on hydrogen peroxide-induced cytotoxicity in HepG2 cells.

  Pharmacological reports : PR 20110101

• Curcumin inhibits neuronal and vascular degeneration in retina after ischemia and reperfusion injury.

  PloS one 20110101

• Curcumin induces EGFR degradation in lung adenocarcinoma and modulates p38 activation in intestine: the versatile adjuvant for gefitinib therapy.

  PloS one 20110101

• Curcumin-loaded apotransferrin nanoparticles provide efficient cellular uptake and effectively inhibit HIV-1 replication in vitro.

  PloS one 20110101

• Alteration of AP-endonuclease1 expression in curcumin-treated fibrotic rats.

  Annals of hepatology 20110101

• Natural antioxidants and vascular calcification: a possible benefit.

  Journal of nephrology 20110101

• Evaluation of antidepressant like activity of curcumin and its combination with fluoxetine and imipramine: an acute and chronic study.

  Acta poloniae pharmaceutica 20110101

• Curcumin is a potent modulator of microglial gene expression and migration.

  Journal of neuroinflammation 20110101

• Hepatoprotective Effect of Curcumin on Lindane-induced Oxidative Stress in Male Wistar Rats.

  Toxicology international 20110101

• Intracellular ROS protection efficiency and free radical-scavenging activity of curcumin.

  PloS one 20110101

• Curcumin attenuates insulin resistance in hepatocytes by inducing Nrf2 nuclear translocation.

  Hepato-gastroenterology 20110101

• Effects of phytochemicals on ionization radiation-mediated carcinogenesis and cancer therapy.

  Mutation research 20110101

• Shattering the underpinnings of neoplastic architecture in LNCap: synergistic potential of nutraceuticals in dampening PDGFR/EGFR signaling and cellular proliferation.

  Journal of experimental therapeutics & oncology 20110101

• Antifibrotic effects of curcumin are associated with overexpression of cathepsins K and L in bleomycin treated mice and human fibroblasts.

  Respiratory research 20110101

• Interaction of curcumin nanoformulations with human plasma proteins and erythrocytes.

  International journal of nanomedicine 20110101

• Collaborative effects of diet and exercise on cognitive enhancement.

  Nutrition and health 20110101

• Ameliorative effects of curcumin on the spermatozoon tail length, count, motility and testosterone serum level in metronidazole-treated mice.

  Prague medical report 20110101

• Antioxidation and tyrosinase inhibition of polyphenolic curcumin analogs.

  Bioscience, biotechnology, and biochemistry 20110101

• Curcumin blocks Kv11.1 (erg) potassium current and slows proliferation in the infant acute monocytic leukemia cell line THP-1.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20110101

• Curcumin mediates presenilin-1 activity to reduce β-amyloid production in a model of Alzheimer's Disease.

  Pharmacological reports : PR 20110101

• A novel neurotrophic drug for cognitive enhancement and Alzheimer's disease.

  PloS one 20110101

• Selective cytotoxicity against human osteosarcoma cells by a novel synthetic C-1 analogue of 7-deoxypancratistatin is potentiated by curcumin.

  PloS one 20110101

• Curcumin induces apoptosis involving bax/bcl-2 in human hepatoma SMMC-7721 cells.

  Asian Pacific journal of cancer prevention : APJCP 20110101

• Effect of curcumin on glucose absorption: an experimental study on albino rats.

  Indian journal of physiology and pharmacology 20110101

• Dietary turmeric potentially reduces the risk of cancer.

  Asian Pacific journal of cancer prevention : APJCP 20110101

• Inhibition of p300-HAT results in a reduced histone acetylation and down-regulation of gene expression in cardiac myocytes.

  Life sciences 20101218

• Pharmacokinetic applicability of a validated liquid chromatography tandem mass spectroscopy method for orally administered curcumin loaded solid lipid nanoparticles to rats.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20101215

• Antihyperlipidemic effect of chlorogenic acid and tetrahydrocurcumin in rats subjected to diabetogenic agents.

  Chemico-biological interactions 20101205

• Anti-inflammatory effects of dietary phenolic compounds in an in vitro model of inflamed human intestinal epithelium.

  Chemico-biological interactions 20101205

• Natural antioxidants synergistically enhance the anticancer potential of AP9-cd, a novel lignan composition from Cedrus deodara in human leukemia HL-60 cells.

  Chemico-biological interactions 20101205

• Identification of Siah-interacting protein as a potential regulator of apoptosis and curcumin resistance.

  Oncogene 20101202

• Antitumor activity of natural compounds, curcumin and PKF118-310, as Wnt/β-catenin antagonists against human osteosarcoma cells.

  Investigational new drugs 20101201

• Cell cycle inhibition and apoptosis induced by curcumin in Ewing sarcoma cell line SK-NEP-1.

  Medical oncology (Northwood, London, England) 20101201

• Curcumin reduces the expression of Bcl-2 by upregulating miR-15a and miR-16 in MCF-7 cells.

  Medical oncology (Northwood, London, England) 20101201

• Antifungal curcumin induces reactive oxygen species and triggers an early apoptosis but prevents hyphae development by targeting the global repressor TUP1 in Candida albicans.

  Bioscience reports 20101201

• Curcumin: a novel nutritionally derived ligand of the vitamin D receptor with implications for colon cancer chemoprevention.

  The Journal of nutritional biochemistry 20101201

• Glutathione transferase from Plasmodium falciparum--interaction with malagashanine and selected plant natural products.

  Journal of enzyme inhibition and medicinal chemistry 20101201

• Transcriptional upregulation of Nrf2-dependent phase II detoxification genes in the involved epidermis of vitiligo vulgaris.

  The Journal of investigative dermatology 20101201

• Curcumin interrupts the interaction between the androgen receptor and Wnt/β-catenin signaling pathway in LNCaP prostate cancer cells.

  Prostate cancer and prostatic diseases 20101201

• Suppression of TGF-β1/SMAD pathway and extracellular matrix production in primary keloid fibroblasts by curcuminoids: its potential therapeutic use in the chemoprevention of keloid.

  Archives of dermatological research 20101201

• 'Poly(ethylene glycol)-magnetic nanoparticles-curcumin' trio: directed morphogenesis and synergistic free-radical scavenging.

  Colloids and surfaces. B, Biointerfaces 20101201

• Curcumin-loaded hydrogel nanoparticles: application in anti-malarial therapy and toxicological evaluation.

  Journal of pharmaceutical sciences 20101201

• Curcumin inhibits carcinogen and nicotine-induced Mammalian target of rapamycin pathway activation in head and neck squamous cell carcinoma.

  Cancer prevention research (Philadelphia, Pa.) 20101201

• Cardiac oxidative stress and inflammation are similar in SAMP8 and SAMR1 mice and unaltered by curcumin and Ginkgo biloba extract intake.

  Current pharmaceutical biotechnology 20101201

• Structurally distinct toxicity inhibitors bind at common loci on β-amyloid fibril.

  Protein science : a publication of the Protein Society 20101201

• Targeting metabolic syndrome: candidate natural agents.

  Journal of diabetes 20101201

• Synthesis and anti-inflammatory evaluation of novel mono-carbonyl analogues of curcumin in LPS-stimulated RAW 264.7 macrophages.

  European journal of medicinal chemistry 20101201

• Curcumin induces maturation-arrested dendritic cells that expand regulatory T cells in vitro and in vivo.

  Clinical and experimental immunology 20101201

• Polycaprolactone diacrylate crosslinked biodegradable semi-interpenetrating networks of polyacrylamide and gelatin for controlled drug delivery.

  Biomedical materials (Bristol, England) 20101201

• Curcumin and obesity: evidence and mechanisms.

  Nutrition reviews 20101201

• Dietary curcumin attenuates glioma growth in a syngeneic mouse model by inhibition of the JAK1,2/STAT3 signaling pathway.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20101201

• Efficacy and safety of Meriva®, a curcumin-phosphatidylcholine complex, during extended administration in osteoarthritis patients.

  Alternative medicine review : a journal of clinical therapeutic 20101201

• The vitamin C:vitamin K3 system - enhancers and inhibitors of the anticancer effect.

  Alternative medicine review : a journal of clinical therapeutic 20101201

• Investigation of the apoptotic effect of curcumin in human leukemia HL-60 cells by using flow cytometry.

  Cancer biotherapy & radiopharmaceuticals 20101201

• Evaluation of antiviral activities of curcumin derivatives against HSV-1 in Vero cell line.

  Natural product communications 20101201

• [Design, optimization and quality evaluation of curcumin self-emulsifying drug delivery system (SEDDS)].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20101201

• Curcumin, resveratrol and flavonoids as anti-inflammatory, cyto- and DNA-protective dietary compounds.

  Toxicology 20101128

• Protective effect of curcumin against seizures and cognitive impairment in a pentylenetetrazole-kindled epileptic rat model.

  Life sciences 20101120

• The inhibitory effects of different curcuminoids on β-amyloid protein, β-amyloid precursor protein and β-site amyloid precursor protein cleaving enzyme 1 in swAPP HEK293 cells.

  Neuroscience letters 20101119

• Potential therapeutic effects of curcumin: relationship to microtubule-associated proteins 2 in Aβ1-42 insult.

  Brain research 20101118

• Microwave-assisted synthesis of novel 2,3-dihydro-4-pyridinones.

  Molecules (Basel, Switzerland) 20101117

• Astrocyte-derived glutathione attenuates hemin-induced apoptosis in cerebral microvascular cells.

  Glia 20101115

• Cellular uptake, retention and bioabsorption of HO-3867, a fluorinated curcumin analog with potential antitumor properties.

  Cancer biology & therapy 20101115

• Synthesis and in vitro/in vivo anti-cancer evaluation of curcumin-loaded chitosan/poly(butyl cyanoacrylate) nanoparticles.

  International journal of pharmaceutics 20101115

• A liquid chromatography-tandem mass spectrometric method for quantification of curcuminoids in cell medium and mouse plasma.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20101115

• The involvement of Smac/DIABLO, p53, NF-kB, and MAPK pathways in apoptosis of keratinocytes from perilesional vitiligo skin: Protective effects of curcumin and capsaicin.

  Antioxidants & redox signaling 20101101

• Curcumin causes superoxide anion production and p53-independent apoptosis in human colon cancer cells.

  Cancer letters 20101101

• Effects of Curcuma extracts and curcuminoids on expression of P-glycoprotein and cytochrome P450 3A4 in the intestinal cell culture model LS180.

  Planta medica 20101101

• Fabrication of curcumin encapsulated PLGA nanoparticles for improved therapeutic effects in metastatic cancer cells.

  Journal of colloid and interface science 20101101

• Antioxidants counteract nicotine and promote migration via RacGTP in oral fibroblast cells.

  Journal of periodontology 20101101

• Development and evaluation of self-microemulsifying liquid and pellet formulations of curcumin, and absorption studies in rats.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20101101

• Curcuminoids-loaded lipid nanoparticles: novel approach towards malaria treatment.

  Colloids and surfaces. B, Biointerfaces 20101101

• Rapid burst of H2O2 by plant growth regulators increases intracellular Ca2+ amounts and modulates CD4+ T cell activation.

  International immunopharmacology 20101101

• Potential protective effects of quercetin and curcumin on paracetamol-induced histological changes, oxidative stress, impaired liver and kidney functions and haematotoxicity in rat.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20101101

• A pyrazole curcumin derivative restores membrane homeostasis disrupted after brain trauma.

  Experimental neurology 20101101

• Curcumin enhances oral bioavailability and anti-tumor therapeutic efficacy of paclitaxel upon administration in nanoemulsion formulation.

  Journal of pharmaceutical sciences 20101101

• Curcumin inhibits the proliferation of human hepatocellular carcinoma J5 cells by inducing endoplasmic reticulum stress and mitochondrial dysfunction.

  International journal of molecular medicine 20101101

• Curcumin promotes apoptosis in human lung adenocarcinoma cells through miR-186* signaling pathway.

  Oncology reports 20101101

• Curcumin attenuates the effects of transport stress on serum cortisol concentration, hippocampal NO production, and BDNF expression in the pig.

  Domestic animal endocrinology 20101101

• Inhibitory effect of epigallocatechin gallate (EGCG), resveratrol, and curcumin on proliferation of human retinal pigment epithelial cells in vitro.

  Current eye research 20101101

• Curcumin prevents leptin raising glucose levels in hepatic stellate cells by blocking translocation of glucose transporter-4 and increasing glucokinase.

  British journal of pharmacology 20101101

• Comparative antioxidant activities and synergism of resveratrol and oxyresveratrol.

  Natural product research 20101101

• Effect of curcumin in the amelioration of pancreatic islets in streptozotocin-induced diabetic mice.

  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20101101

• [Effects of curcumin on apoptosis and caspase-3 expression in cortex tissue in rats with hypoxic ischemic brain damage].

  Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20101101

• Enhanced oral bioavailability of docetaxel in rats by four consecutive days of pre-treatment with curcumin.

  International journal of pharmaceutics 20101031

• Copper curcuminoids containing anthracene groups: fluorescent molecules with cytotoxic activity.

  Inorganic chemistry 20101018

• Development of curcumin as an epigenetic agent.

  Cancer 20101015

• Transferrin mediated solid lipid nanoparticles containing curcumin: enhanced in vitro anticancer activity by induction of apoptosis.

  International journal of pharmaceutics 20101015

• A general HPLC-UV method for the quantitative determination of curcumin analogues containing the 1,5-diaryl-3-oxo-1,4-pentadienyl pharmacophore in rat biomatrices.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20101015

• Alzheimer's disease amyloid beta converting left-handed Z-DNA back to right-handed B-form.

  Chemical communications (Cambridge, England) 20101014

• Polyamine conjugation of curcumin analogues toward the discovery of mitochondria-directed neuroprotective agents.

  Journal of medicinal chemistry 20101014

• Curcuminoids suppress the growth and induce apoptosis through caspase-3-dependent pathways in glioblastoma multiforme (GBM) 8401 cells.

  Journal of agricultural and food chemistry 20101013

• Potential of the dietary antioxidants resveratrol and curcumin in prevention and treatment of hematologic malignancies.

  Molecules (Basel, Switzerland) 20101012

• Curcumin ameliorates cognitive dysfunction and oxidative damage in phenobarbitone and carbamazepine administered rats.

  European journal of pharmacology 20101010

• Curcumin p38-dependently enhances the anticancer activity of valproic acid in human leukemia cells.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20101009

• Poly(β-cyclodextrin)/curcumin self-assembly: a novel approach to improve curcumin delivery and its therapeutic efficacy in prostate cancer cells.

  Macromolecular bioscience 20101008

• Spectroscopic properties of curcumin: orientation of transition moments.

  The journal of physical chemistry. B 20101007

• 3-Caffeoyl, 4-dihydrocaffeoylquinic acid from Salicornia herbacea inhibits tumor cell invasion by regulating protein kinase C-delta-dependent matrix metalloproteinase-9 expression.

  Toxicology letters 20101005

• Curcumin modulates eukaryotic initiation factors in human lung adenocarcinoma epithelial cells.

  Molecular biology reports 20101001

• Curcumin inhibits TNFalpha-induced lectin-like oxidised LDL receptor-1 (LOX-1) expression and suppresses the inflammatory response in human umbilical vein endothelial cells (HUVECs) by an antioxidant mechanism.

  Journal of enzyme inhibition and medicinal chemistry 20101001

• REVIEW: Curcumin and Alzheimer's disease.

  CNS neuroscience & therapeutics 20101001

• C6 ceramide potentiates curcumin-induced cell death and apoptosis in melanoma cell lines in vitro.

  Cancer chemotherapy and pharmacology 20101001

• Preparation, characterization, pharmacokinetics, and tissue distribution of curcumin nanosuspension with TPGS as stabilizer.

  Drug development and industrial pharmacy 20101001

• Cyclodextrin-complexed curcumin exhibits anti-inflammatory and antiproliferative activities superior to those of curcumin through higher cellular uptake.

  Biochemical pharmacology 20101001

• Curcumin prevents cardiac remodeling secondary to chronic renal failure through deactivation of hypertrophic signaling in rats.

  American journal of physiology. Heart and circulatory physiology 20101001

• Curcumin stimulates reactive oxygen species production and potentiates apoptosis induction by the antitumor drugs arsenic trioxide and lonidamine in human myeloid leukemia cell lines.

  The Journal of pharmacology and experimental therapeutics 20101001

• Neuroprotective effects of the polyphenolic antioxidant agent, Curcumin, against homocysteine-induced cognitive impairment and oxidative stress in the rat.

  Pharmacology, biochemistry, and behavior 20101001

• Curcumin extends life span, improves health span, and modulates the expression of age-associated aging genes in Drosophila melanogaster.

  Rejuvenation research 20101001

• Toxicity prediction of compounds from turmeric (Curcuma longa L).

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20101001

• Isoxazole analogs of curcuminoids with highly potent multidrug-resistant antimycobacterial activity.

  European journal of medicinal chemistry 20101001

• Molecular mechanisms for curcumin benefits against ischemic injury.

  Fertility and sterility 20101001

• Evaluation of curcumin acetates and amino acid conjugates as proteasome inhibitors.

  International journal of molecular medicine 20101001

• Hypoxia inducible factor-1α expression in areca quid chewing-associated oral squamous cell carcinomas.

  Oral diseases 20101001

• Effect of cytochrome P450 and aldo-keto reductase inhibitors on progesterone inactivation in primary bovine hepatic cell cultures.

  Journal of dairy science 20101001

• Curcumin enhances the effect of cisplatin in suppression of head and neck squamous cell carcinoma via inhibition of IKKβ protein of the NFκB pathway.

  Molecular cancer therapeutics 20101001

• Tetrahydrocurcuminoid cream plus targeted narrowband UVB phototherapy for vitiligo: a preliminary randomized controlled study.

  Photomedicine and laser surgery 20101001

• Curcumin-altered p53-response genes regulate radiosensitivity in p53-mutant Ewing's sarcoma cells.

  Anticancer research 20101001

• Anti-proliferation and anti-angiogenesis of curcumin-K30 solid dispersion.

  Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20101001

• Anti-inflammatory mechanisms of compounds from Curcuma mangga rhizomes using RAW264.7 macrophage cells.

  Natural product communications 20101001

• Ultrafast dynamics of the excited states of curcumin in solution.

  The journal of physical chemistry. B 20100923

• Development and validation of UPLC method for quality control of Curcuma longa Linn.: Fast simultaneous quantitation of three curcuminoids.

  Journal of pharmaceutical and biomedical analysis 20100921

• GABAergic and nitriergic modulation by curcumin for its antianxiety-like activity in mice.

  Brain research 20100917

• In vitro biological evaluation of electrospun cellulose acetate fiber mats containing asiaticoside or curcumin.

  Journal of biomedical materials research. Part A 20100915

• Synthesis and cytotoxic potential of heterocyclic cyclohexanone analogues of curcumin.

  Bioorganic & medicinal chemistry 20100915

• Effects of glutamine and curcumin on bacterial translocation in jaundiced rats.

  World journal of gastroenterology 20100914

• Curcumin decreases amyloid-beta peptide levels by attenuating the maturation of amyloid-beta precursor protein.

  The Journal of biological chemistry 20100910

• Specific Inhibition of NEIL-initiated repair of oxidized base damage in human genome by copper and iron: potential etiological linkage to neurodegenerative diseases.

  The Journal of biological chemistry 20100910

• Chemoprotective effects of curcumin in esophageal epithelial cells exposed to bile acids.

  World journal of gastroenterology 20100907

• Assessment of cell viability, lipid peroxidation and quantification of DNA fragmentation after the treatment of anticancerous drug mitomycin C and curcumin in cultured human blood lymphocytes.

  Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20100901

• Curcumin and its analogues: potential anticancer agents.

  Medicinal research reviews 20100901

• Modulatory effects of curcumin and resveratrol on lung carcinogenesis in mice.

  Phytotherapy research : PTR 20100901

• 6-Shogaol is more effective than 6-gingerol and curcumin in inhibiting 12-O-tetradecanoylphorbol 13-acetate-induced tumor promotion in mice.

  Molecular nutrition & food research 20100901

• Neuroprotective effect of curcumin in arsenic-induced neurotoxicity in rats.

  Neurotoxicology 20100901

• Curcumin inhibits reactive oxygen species formation and vascular hyperpermeability following haemorrhagic shock.

  Clinical and experimental pharmacology & physiology 20100901

• Curcumin improves early functional results after experimental spinal cord injury.

  Acta neurochirurgica 20100901

• Curcuminoids enhance memory in an amyloid-infused rat model of Alzheimer's disease.

  Neuroscience 20100901

• The in vitro stability and in vivo pharmacokinetics of curcumin prepared as an aqueous nanoparticulate formulation.

  Biomaterials 20100901

• A novel nanoparticle drug delivery system: the anti-inflammatory activity of curcumin is enhanced when encapsulated in exosomes.

  Molecular therapy : the journal of the American Society of Gene Therapy 20100901

• Curcumin polymers as anticancer conjugates.

  Biomaterials 20100901

• Probing the binding site of curcumin in Escherichia coli and Bacillus subtilis FtsZ--a structural insight to unveil antibacterial activity of curcumin.

  European journal of medicinal chemistry 20100901

• Curcumin protects hepatic stellate cells against leptin-induced activation in vitro by accumulating intracellular lipids.

  Endocrinology 20100901

• Curcumin in cancer chemoprevention: molecular targets, pharmacokinetics, bioavailability, and clinical trials.

  Archiv der Pharmazie 20100901

• IL-6, a risk factor for hepatocellular carcinoma: FLLL32 inhibits IL-6-induced STAT3 phosphorylation in human hepatocellular cancer cells.

  Cell cycle (Georgetown, Tex.) 20100901

• Transient metals enhance cytotoxicity of curcumin: potential involvement of the NF-kappaB and mTOR signaling pathways.

  Anticancer research 20100901

• The effect of curcumin on human islet amyloid polypeptide misfolding and toxicity.

  Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 20100901

• [Studies on reversing MDR of K562/A02 by ramification of curcumin hydrolyzed].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100901

• [Study on the content of curcumin by HPLC and the anti-tumor effect in vivo from different processed products of Curuma kwangsiensis].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20100901

• Curcumin suppresses gastric NF-kappaB activation and macromolecular leakage in Helicobacter pylori-infected rats.

  World journal of gastroenterology 20100828

• Nitric oxide-mediated histone hyperacetylation in oral cancer: target for a water-soluble HAT inhibitor, CTK7A.

  Chemistry & biology 20100827

• 'Clicked' bivalent ligands containing curcumin and cholesterol as multifunctional abeta oligomerization inhibitors: design, synthesis, and biological characterization.

  Journal of medicinal chemistry 20100826

• Targeting inflammation-induced obesity and metabolic diseases by curcumin and other nutraceuticals.

  Annual review of nutrition 20100821

• Inhibition of NFkappaB and pancreatic cancer cell and tumor growth by curcumin is dependent on specificity protein down-regulation.

  The Journal of biological chemistry 20100813

• A novel Ca2+/calmodulin antagonist HBC inhibits angiogenesis and down-regulates hypoxia-inducible factor.

  The Journal of biological chemistry 20100813

• Curcumin promotes apoptosis in A549/DDP multidrug-resistant human lung adenocarcinoma cells through an miRNA signaling pathway.

  Biochemical and biophysical research communications 20100813

• Potential protection of curcumin against intracellular amyloid beta-induced toxicity in cultured rat prefrontal cortical neurons.

  Neuroscience letters 20100809

• Curcumin decreases toll-like receptor-2 gene expression and function in human monocytes and neutrophils.

  Biochemical and biophysical research communications 20100806

• Curcumin disorders 1,2-dipalmitoyl-sn-glycero-3-phosphocholine membranes and favors the formation of nonlamellar structures by 1,2-dielaidoyl-sn-glycero-3-phosphoethanolamine.

  The journal of physical chemistry. B 20100805

• Targeting breast stem cells with the cancer preventive compounds curcumin and piperine.

  Breast cancer research and treatment 20100801

• Evaluation of curcumin and cisplatin-induced DNA damage in PC12 cells by the alkaline comet assay.

  Human & experimental toxicology 20100801

• Curcumin inhibits tumor growth and angiogenesis in glioblastoma xenografts.

  Molecular nutrition & food research 20100801

• Heat-solubilized curry spice curcumin inhibits antibody-antigen interaction in in vitro studies: a possible therapy to alleviate autoimmune disorders.

  Molecular nutrition & food research 20100801

• Synthesis and antileishmanial and antimicrobial activities of some 2,3-disubstituted 3H-quinazolin-4-ones.

  Journal of enzyme inhibition and medicinal chemistry 20100801

• Comparative and combined effect of chlorogenic acid and tetrahydrocurcumin on antioxidant disparities in chemical induced experimental diabetes.

  Molecular and cellular biochemistry 20100801

• Curcumin selectively induces apoptosis in cutaneous T-cell lymphoma cell lines and patients' PBMCs: potential role for STAT-3 and NF-kappaB signaling.

  The Journal of investigative dermatology 20100801

• The effect of curcumin on insulin release in rat-isolated pancreatic islets.

  Angiology 20100801

• Effect of dimethylsulphoxide and curcumin on protein carbonyls and reactive oxygen species of cerebral hemispheres of mice as a function of age.

  International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20100801

• Inhibitory effect of encapsulated curcumin on ultraviolet-induced photoaging in mice.

  Rejuvenation research 20100801

• Up-regulation of heme oxygenase-1 expression through CaMKII-ERK1/2-Nrf2 signaling mediates the anti-inflammatory effect of bisdemethoxycurcumin in LPS-stimulated macrophages.

  Free radical biology & medicine 20100801

• The photo- and electrophysical properties of curcumin in aqueous solution.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20100801

• Enhanced glutathione efflux from astrocytes in culture by low extracellular Ca2+ and curcumin.

  Neurochemical research 20100801

• beta-Cyclodextrin-curcumin self-assembly enhances curcumin delivery in prostate cancer cells.

  Colloids and surfaces. B, Biointerfaces 20100801

• Synergistic anticandidal activity of pure polyphenol curcumin I in combination with azoles and polyenes generates reactive oxygen species leading to apoptosis.

  FEMS yeast research 20100801

• Curcumin exerts neuroprotective effects against homocysteine intracerebroventricular injection-induced cognitive impairment and oxidative stress in rat brain.

  Journal of medicinal food 20100801

• Evaluation of novel alginate foams as drug delivery systems in antimicrobial photodynamic therapy (aPDT) of infected wounds--an in vitro study: studies on curcumin and curcuminoides XL.

  Journal of pharmaceutical sciences 20100801

• Potential response to curcumin in infantile hemangioendothelioma of the liver.

  Pediatric blood & cancer 20100801

• Curcumin disrupts meiotic and mitotic divisions via spindle impairment and inhibition of CDK1 activity.

  Cell proliferation 20100801

• The anti-cancer efficacy of curcumin scrutinized through core signaling pathways in glioblastoma.

  International journal of molecular medicine 20100801

• New role of (-)-epicatechin in enhancing the induction of growth inhibition and apoptosis in human lung cancer cells by curcumin.

  Cancer prevention research (Philadelphia, Pa.) 20100801

• Curcumin suppresses the dynamic instability of microtubules, activates the mitotic checkpoint and induces apoptosis in MCF-7 cells.

  The FEBS journal 20100801

• Systemic administration of polymeric nanoparticle-encapsulated curcumin (NanoCurc) blocks tumor growth and metastases in preclinical models of pancreatic cancer.

  Molecular cancer therapeutics 20100801

• Distinct combinatorial effects of the plant polyphenols curcumin, carnosic acid, and silibinin on proliferation and apoptosis in acute myeloid leukemia cells.

  Nutrition and cancer 20100801

• Curcumin modulates leukocyte and platelet adhesion in murine sepsis.

  Microcirculation (New York, N.Y. : 1994) 20100801

• The role of antioxidants and iron chelators in the treatment of oxidative stress in thalassemia.

  Annals of the New York Academy of Sciences 20100801

• Separation of curcuminoids enriched fraction from spent turmeric oleoresin and its antioxidant potential.

  Journal of food science 20100801

• Amphiphilic curcumin conjugate-forming nanoparticles as anticancer prodrug and drug carriers: in vitro and in vivo effects.

  Nanomedicine (London, England) 20100801

• Modulatory effects of natural curcuminoids on P-glycoprotein ATPase of insecticide-resistant pest Helicoverpa armigera (Lepidopetera: Noctüidae).

  The Journal of membrane biology 20100801

• Photokilling of bacteria by curcumin in selected polyethylene glycol 400 (PEG 400) preparations. Studies on curcumin and curcuminoids, XLI.

  Die Pharmazie 20100801

• [In vitro pharmacodynamic interactions of antitumor effect of the combination of adriamycin and curcumin evaluated by the parameter method and the response surface].

  Yao xue xue bao = Acta pharmaceutica Sinica 20100801

• Novel water-soluble curcumin derivative mediating erectile signaling.

  The journal of sexual medicine 20100801

• Reduction of periductal fibrosis in liver fluke-infected hamsters after long-term curcumin treatment.

  European journal of pharmacology 20100725

• Curcumin induces down-regulation of EZH2 expression through the MAPK pathway in MDA-MB-435 human breast cancer cells.

  European journal of pharmacology 20100710

• Curcumin inhibits the side population (SP) phenotype of the rat C6 glioma cell line: towards targeting of cancer stem cells with phytochemicals.

  Cancer letters 20100701

• Curcumin upregulates insulin-like growth factor binding protein-5 (IGFBP-5) and C/EBPalpha during oral cancer suppression.

  International journal of cancer 20100701

• Fluorescence enhancement of the silver nanoparticales--curcumin-cetyltrimethylammonium bromide-nucleic acids system and its analytical application.

  Journal of fluorescence 20100701

• Detoxification and antioxidant effects of curcumin in rats experimentally exposed to mercury.

  Journal of applied toxicology : JAT 20100701

• Curcumin reverses T cell-mediated adaptive immune dysfunctions in tumor-bearing hosts.

  Cellular & molecular immunology 20100701

• NF-E2-related factor 2, a key inducer of antioxidant defenses, negatively regulates the CFTR transcription.

  Cellular and molecular life sciences : CMLS 20100701

• Chloramphenicol causes mitochondrial stress, decreases ATP biosynthesis, induces matrix metalloproteinase-13 expression, and solid-tumor cell invasion.

  Toxicological sciences : an official journal of the Society of Toxicology 20100701

• Acyl modified chitosan derivatives for oral delivery of insulin and curcumin.

  Journal of materials science. Materials in medicine 20100701

• COX-2 and PGE2 signaling is essential for the regulation of IDO expression by curcumin in murine bone marrow-derived dendritic cells.

  International immunopharmacology 20100701

• A validated method for the quantification of curcumin in plasma and brain tissue by fast narrow-bore high-performance liquid chromatography with fluorescence detection.

  Analytical and bioanalytical chemistry 20100701

• Food preservatives sodium benzoate and propionic acid and colorant curcumin suppress Th1-type immune response in vitro.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100701

• Investigation of the anti-inflammatory effect of Curcuma longa in Helicobacter pylori-infected patients.

  International immunopharmacology 20100701

• Proximal human FOXP3 promoter transactivated by NF-kappaB and negatively controlled by feedback loop and SP3.

  Molecular immunology 20100701

• Substrate specificity of the mitochondrial thioredoxin reductase of the parasitic nematode Haemonchus contortus.

  Parasitology research 20100701

• Combined inhibitory effects of soy isoflavones and curcumin on the production of prostate-specific antigen.

  The Prostate 20100701

• Curcumin suppresses alpha-melanocyte stimulating hormone-stimulated melanogenesis in B16F10 cells.

  International journal of molecular medicine 20100701

• Natural products inhibit LPS-induced activation of pro-inflammatory cytokines in peripheral blood mononuclear cells.

  Natural product research 20100701

• The inhibitory effect of turmeric curcuminoids on matrix metalloproteinase-3 secretion in human invasive breast carcinoma cells.

  Archives of pharmacal research 20100701

• Curcumin alters the migratory phenotype of nasopharyngeal carcinoma cells through up-regulation of E-cadherin.

  Anticancer research 20100701

• Curcumin therapeutic promises and bioavailability in colorectal cancer.

  Drugs of today (Barcelona, Spain : 1998) 20100701

• [Curcumin inhibits hypoxia-induced proliferation of MRC-5 and collagen I synthesis].

  Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20100701

• Dietary polyphenols and obesity.

  Nutrients 20100701

• Curcumin nanoparticles improve the physicochemical properties of curcumin and effectively enhance its antioxidant and antihepatoma activities.

  Journal of agricultural and food chemistry 20100623

• Curcumin protects pre-oligodendrocytes from activated microglia in vitro and in vivo.

  Brain research 20100621

• Suppression of PMA-induced tumor cell invasion by dihydroartemisinin via inhibition of PKCalpha/Raf/MAPKs and NF-kappaB/AP-1-dependent mechanisms.

  Biochemical pharmacology 20100615

• Electroanalytical study of the interaction between dsDNA and curcumin in the presence of copper(II).

  Talanta 20100615

• ApoE3 mediated poly(butyl) cyanoacrylate nanoparticles containing curcumin: study of enhanced activity of curcumin against beta amyloid induced cytotoxicity using in vitro cell culture model.

  Molecular pharmaceutics 20100607

• Curcumin inhibits hepatitis B virus via down-regulation of the metabolic coactivator PGC-1alpha.

  FEBS letters 20100603

• Effects of Curcuma spp. on P-glycoprotein function.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20100601

• Curcumin protects against hepatic and renal injuries mediated by inducible nitric oxide synthase during selenium-induced toxicity in Wistar rats.

  Microscopy research and technique 20100601

• Curcumin protects DNA damage in a chronically arsenic-exposed population of West Bengal.

  Human & experimental toxicology 20100601

• Modulation of cerebral malaria by fasudil and other immune-modifying compounds.

  Experimental parasitology 20100601

• Curcumin as a therapeutic agent: the evidence from in vitro, animal and human studies.

  The British journal of nutrition 20100601

• Bisdemethylcurcumin and structurally related hispolon analogues of curcumin exhibit enhanced prooxidant, anti-proliferative and anti-inflammatory activities in vitro.

  Biochemical pharmacology 20100601

• Systematic analysis of the antiproliferative effects of novel and standard anticancer agents in rhabdoid tumor cell lines.

  Anti-cancer drugs 20100601

• Novel 3-alkanoyl/aroyl/heteroaroyl-2H-chromene-2-thiones: synthesis and evaluation of their antioxidant activities.

  European journal of medicinal chemistry 20100601

• Curcumin stimulates glucose uptake through AMPK-p38 MAPK pathways in L6 myotube cells.

  Journal of cellular physiology 20100601

• Modulatory effect of curcumin on survival of irradiated human intestinal microvascular endothelial cells: role of Akt/mTOR and NF-{kappa}B.

  American journal of physiology. Gastrointestinal and liver physiology 20100601

• Immunological studies on Amaranth, Sunset Yellow and Curcumin as food colouring agents in albino rats.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100601

• Lesson learned from nature for the development of novel anti-cancer agents: implication of isoflavone, curcumin, and their synthetic analogs.

  Current pharmaceutical design 20100601

• Curcumin-induced suppression of adipogenic differentiation is accompanied by activation of Wnt/beta-catenin signaling.

  American journal of physiology. Cell physiology 20100601

• N-acetyl cysteine mitigates curcumin-mediated telomerase inhibition through rescuing of Sp1 reduction in A549 cells.

  Mutation research 20100601

• Involvement of PPAR-gamma in curcumin-mediated beneficial effects in experimental dementia.

  Naunyn-Schmiedeberg's archives of pharmacology 20100601

• Critical need for clinical trials: an example of a pilot human intervention trial of a mixture of natural agents protecting lymphocytes against TNF-alpha induced activation of NF-kappaB.

  Pharmaceutical research 20100601

• Potentiation of gemcitabine by Turmeric Force in pancreatic cancer cell lines.

  Oncology reports 20100601

• Why pleiotropic interventions are needed for Alzheimer's disease.

  Molecular neurobiology 20100601

• Chemoprevention strategies for pancreatic cancer.

  Nature reviews. Gastroenterology & hepatology 20100601

• Curcuminoids activate p38 MAP kinases and promote UVB-dependent signalling in keratinocytes.

  Experimental dermatology 20100601

• Sonication-assisted synthesis of polyelectrolyte-coated curcumin nanoparticles.

  Langmuir : the ACS journal of surfaces and colloids 20100601

• Injectable sustained release microparticles of curcumin: a new concept for cancer chemoprevention.

  Cancer research 20100601

• Hepatoprotective role of bis-demethoxy curcumin analog on the expression of matrix metalloproteinase induced by alcohol and polyunsaturated fatty acid in rats.

  Toxicology mechanisms and methods 20100601

• Novel heart failure therapy targeting transcriptional pathway in cardiomyocytes by a natural compound, curcumin.

  Circulation journal : official journal of the Japanese Circulation Society 20100601

• Plant polyphenol curcumin significantly affects CYP1A2 and CYP2A6 activity in healthy, male Chinese volunteers.

  The Annals of pharmacotherapy 20100601

• Potential of curcumin as a multifunctional agent to combat Wilson disease.

  Hepatology (Baltimore, Md.) 20100601

• [Biological characteristics of Wt1 gene in relation to Ph(+) leukemia cell line K562].

  Zhongguo shi yan xue ye xue za zhi 20100601

• Clinical relevance of curcumin-induced immunosuppression in living-related donor renal transplant: an in vitro analysis.

  Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20100601

• Possible action mechanism for curcumin in pre-cancerous lesions based on serum and salivary markers of oxidative stress.

  Journal of oral science 20100601

• Possible links between intestinal permeability and food processing: A potential therapeutic niche for glutamine.

  Clinics (Sao Paulo, Brazil) 20100601

• Colon targeted curcumin delivery using guar gum.

  Natural product communications 20100601

• Curcumin targeted signaling pathways: basis for anti-photoaging and anti-carcinogenic therapy.

  International journal of dermatology 20100601

• Curcumin induces apoptosis in human non-small cell lung cancer NCI-H460 cells through ER stress and caspase cascade- and mitochondria-dependent pathways.

  Anticancer research 20100601

• Product-evaluation registry of Meriva®, a curcumin-phosphatidylcholine complex, for the complementary management of osteoarthritis.

  Panminerva medica 20100601

• Lovastatin interacts with natural products to influence cultured hepatocarcinoma cell (hep-g2) growth.

  Journal of the American College of Nutrition 20100601

• Androgen receptor promotes hepatitis B virus-induced hepatocarcinogenesis through modulation of hepatitis B virus RNA transcription.

  Science translational medicine 20100519

• Loading of curcumin in polyelectrolyte multilayers.

  Langmuir : the ACS journal of surfaces and colloids 20100518

• Curcumin suppresses constitutive activation of STAT-3 by up-regulating protein inhibitor of activated STAT-3 (PIAS-3) in ovarian and endometrial cancer cells.

  Journal of cellular biochemistry 20100515

• Oral administration of curcumin emulsified in carboxymethyl cellulose has a potent anti-inflammatory effect in the IL-10 gene-deficient mouse model of IBD.

  Digestive diseases and sciences 20100501

• Mechanical stretch enhances NF-kappaB-dependent gene expression and poly(ADP-ribose) synthesis in synovial cells.

  Journal of biochemistry 20100501

• Curcumin inhibits fibrosis-related effects in IPF fibroblasts and in mice following bleomycin-induced lung injury.

  American journal of physiology. Lung cellular and molecular physiology 20100501

• Comparative effects of curcumin and resveratrol on aflatoxin B(1)-induced liver injury in rats.

  Archives of toxicology 20100501

• Curcumin sensitizes non-small cell lung cancer cell anoikis through reactive oxygen species-mediated Bcl-2 downregulation.

  Apoptosis : an international journal on programmed cell death 20100501

• Curcumin attenuates cerebral edema following traumatic brain injury in mice: a possible role for aquaporin-4?

  Journal of neurochemistry 20100501

• Curcumin supplementation protects from genotoxic effects of arsenic and fluoride.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100501

• Relationship between the tautomeric structures of curcumin derivatives and their Abeta-binding activities in the context of therapies for Alzheimer's disease.

  Biomaterials 20100501

• Curcumin attenuates inflammatory response in IL-1beta-induced human synovial fibroblasts and collagen-induced arthritis in mouse model.

  International immunopharmacology 20100501

• Curcumin inhibits hepatic protein-tyrosine phosphatase 1B and prevents hypertriglyceridemia and hepatic steatosis in fructose-fed rats.

  Hepatology (Baltimore, Md.) 20100501

• IL-6 and high glucose synergistically upregulate MMP-1 expression by U937 mononuclear phagocytes via ERK1/2 and JNK pathways and c-Jun.

  Journal of cellular biochemistry 20100501

• The aberrant expressions of nuclear matrix proteins during the apoptosis of human osteosarcoma cells.

  Anatomical record (Hoboken, N.J. : 2007) 20100501

• Perspectives on chemopreventive and therapeutic potential of curcumin analogs in medicinal chemistry.

  Mini reviews in medicinal chemistry 20100501

• Cancer stem cells: a novel paradigm for cancer prevention and treatment.

  Mini reviews in medicinal chemistry 20100501

• Monoacetylcurcumin strongly regulates inflammatory responses through inhibition of NF-kappaB activation.

  International journal of molecular medicine 20100501

• Curcumin induces mitochondria pathway mediated cell apoptosis in A549 lung adenocarcinoma cells.

  Oncology reports 20100501

• Synthesis and biological analysis of a new curcumin analogue for enhanced anti-tumor activity in HepG 2 cells.

  Oncology reports 20100501

• Gemcitabine sensitivity can be induced in pancreatic cancer cells through modulation of miR-200 and miR-21 expression by curcumin or its analogue CDF.

  Cancer research 20100501

• Drugs that target specificity proteins downregulate epidermal growth factor receptor in bladder cancer cells.

  Molecular cancer research : MCR 20100501

• Dietary curcumin increases antioxidant defenses in lung, ameliorates radiation-induced pulmonary fibrosis, and improves survival in mice.

  Radiation research 20100501

• From kitchen to gut: curcumin in cholestasis.

  Gut 20100501

• SAHA and curcumin combinations co-enhance histone acetylation in human cancer cells but operate antagonistically in exerting cytotoxic effects.

  Journal of Asian natural products research 20100501

• Antioxidant potential of curcumin against oxidative insult induced by pentylenetetrazol in epileptic rats.

  Methods and findings in experimental and clinical pharmacology 20100501

• Tissue distribution & elimination of capsaicin, piperine & curcumin following oral intake in rats.

  The Indian journal of medical research 20100501

• [Preparation and characterization of curcumin polybutylcyanoacrylate nanoparticles].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20100501

• Curcumin dramatically enhances retinoic acid-induced superoxide generating activity via accumulation of p47-phox and p67-phox proteins in U937 cells.

  Biochemical and biophysical research communications 20100423

• The role of charge in the surfactant-assisted stabilization of the natural product curcumin.

  Langmuir : the ACS journal of surfaces and colloids 20100420

• [Curcumin promoted the apoptosis of cisplain-resistant human lung carcinoma cells A549/DDP through down-regulating miR-186*].

  Zhongguo fei ai za zhi = Chinese journal of lung cancer 20100420

• Curcumin derivatives inhibit testicular 17beta-hydroxysteroid dehydrogenase 3.

  Bioorganic & medicinal chemistry letters 20100415

• Common botanical compounds inhibit the hedgehog signaling pathway in prostate cancer.

  Cancer research 20100415

• Modulation of curcumin-induced Akt phosphorylation and apoptosis by PI3K inhibitor in MCF-7 cells.

  Biochemical and biophysical research communications 20100409

• Activation of muscarinic M-1 cholinoceptors by curcumin to increase contractility in urinary bladder isolated from Wistar rats.

  Neuroscience letters 20100405

• A pyrazole derivative of curcumin enhances memory.

  Neurobiology of aging 20100401

• Curcumin inhibits nuclear localization of telomerase by dissociating the Hsp90 co-chaperone p23 from hTERT.

  Cancer letters 20100401

• Reversal of multidrug resistance by curcumin through FA/BRCA pathway in multiple myeloma cell line MOLP-2/R.

  Annals of hematology 20100401

• Inhibitory effect of curcumin on motility of human oral squamous carcinoma YD-10B cells via suppression of ERK and NF-kappaB activations.

  Phytotherapy research : PTR 20100401

• Formulation design and photochemical studies on nanocrystal solid dispersion of curcumin with improved oral bioavailability.

  Journal of pharmaceutical sciences 20100401

• The dark side of curcumin.

  International journal of cancer 20100401

• Antioxidant activities of curcumin and combinations of this curcuminoid with other phytochemicals.

  Phytotherapy research : PTR 20100401

• Modulation of carbohydrate metabolism during N-methyl N-nitrosourea induced neurotoxicity in mice: role of curcumin.

  Neurochemical research 20100401

• Curcumin alone and in combination with augmentin protects against pulmonary inflammation and acute lung injury generated during Klebsiella pneumoniae B5055-induced lung infection in BALB/c mice.

  Journal of medical microbiology 20100401

• Lead induces the expression of endoplasmic reticulum chaperones GRP78 and GRP94 in vascular endothelial cells via the JNK-AP-1 pathway.

  Toxicological sciences : an official journal of the Society of Toxicology 20100401

• Curcumin protects rat myocardium against isoproterenol-induced ischemic injury: attenuation of ventricular dysfunction through increased expression of Hsp27 along with strengthening antioxidant defense system.

  Journal of cardiovascular pharmacology 20100401

• Insulin-like growth factors are more effective than progastrin in reversing proapoptotic effects of curcumin: critical role of p38MAPK.

  American journal of physiology. Gastrointestinal and liver physiology 20100401

• Distinct subcellular localization in the cytosol and apicoplast, unexpected dimerization and inhibition of Plasmodium falciparum glyoxalases.

  Molecular microbiology 20100401

• Protective role of curcumin on lindane induced reproductive toxicity in male Wistar rats.

  Bulletin of environmental contamination and toxicology 20100401

• Re-balancing of inflammation and abeta immunity as a therapeutic for Alzheimer's disease-view from the bedside.

  CNS & neurological disorders drug targets 20100401

• Ameliorative effects of curcumin on the seminiferous epithelium in metronidazole-treated mice: a stereological study.

  Toxicologic pathology 20100401

• Bioconjugates of curcumin display improved protection against glutathione depletion mediated oxidative stress in a dopaminergic neuronal cell line: Implications for Parkinson's disease.

  Bioorganic & medicinal chemistry 20100401

• Is curcumin for monoclonal gammopathy of undetermined significance without risk?--letter.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20100401

• Curcumin improves sclerosing cholangitis in Mdr2-/- mice by inhibition of cholangiocyte inflammatory response and portal myofibroblast proliferation.

  Gut 20100401

• Synthesis of mono-carbonyl analogues of curcumin and their effects on inhibition of cytokine release in LPS-stimulated RAW 264.7 macrophages.

  Bioorganic & medicinal chemistry 20100401

• [Development of anti-Alzheimer's disease drug based on beta-amyloid hypothesis].

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20100401

• The effect of curcumin on corneal neovascularization in rabbit eyes.

  Current eye research 20100401

• Curcumin induces cell death in human uveal melanoma cells through mitochondrial pathway.

  Current eye research 20100401

• Curcumin potentiates the pro-apoptotic effects of sulindac sulfone in colorectal cancer.

  Expert opinion on investigational drugs 20100401

• Biphasic modulation of cocaine-induced conditioned place preference through inhibition of histone acetyltransferase and histone deacetylase.

  Saudi medical journal 20100401

• Curcumin-encapsulated MePEG/PCL diblock copolymeric micelles: a novel controlled delivery vehicle for cancer therapy.

  Nanomedicine (London, England) 20100401

• [Apoptosis of retinoic acid resistant NB4-R1 cells induced with curcumin and its mechanism].

  Zhongguo shi yan xue ye xue za zhi 20100401

• Curcumin reduces angiotensin II-mediated cardiomyocyte growth via LOX-1 inhibition.

  Journal of cardiovascular pharmacology 20100401

• Reversal of MDR1 gene-dependent multidrug resistance in HL60/HT9 cells using short hairpin RNA expression vectors.

  Cancer biotherapy & radiopharmaceuticals 20100401

• Curcumin attenuates airway hyperreactivity induced by ischemia-reperfusion of the pancreas in rats.

  Transplantation proceedings 20100401

• Curcumin labeling of neuronal fibrillar tau inclusions in human brain samples.

  Journal of neuropathology and experimental neurology 20100401

• [Effects of glycyrrhizic acid and solid dispersions of curcumin on anti-oxidation and components of lung lavage fluid of SiO2 exposed rats].

  Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20100401

• Grp94 acts as a mediator of curcumin-induced antioxidant defence in myogenic cells.

  Journal of cellular and molecular medicine 20100401

• [Effects of curcumin on sarcoplasmic reticulum Ca2+-ATPase in rabbits with heart failure].

  Zhonghua xin xue guan bing za zhi 20100401

• Phytochemicals in cancer prevention and therapy: truth or dare?

  Toxins 20100401

• Akt Cys-310-targeted inhibition by hydroxylated benzene derivatives is tightly linked to their immunosuppressive effects.

  The Journal of biological chemistry 20100326

• Curcumin alleviates ethanol-induced hepatocytes oxidative damage involving heme oxygenase-1 induction.

  Journal of ethnopharmacology 20100324

• Novel STAT3 phosphorylation inhibitors exhibit potent growth-suppressive activity in pancreatic and breast cancer cells.

  Cancer research 20100315

• Resveratrol, genistein, and curcumin bind bovine serum albumin.

  The journal of physical chemistry. B 20100311

• Preparation of curcumin sub-micrometer dispersions by high-pressure homogenization.

  Journal of agricultural and food chemistry 20100310

• Excited-state intramolecular hydrogen atom transfer of curcumin in surfactant micelles.

  The journal of physical chemistry. B 20100304

• Curcumin attenuates oxidative stress and inflammatory response in the early phase after partial hepatectomy with simultaneous intraabdominal infection in rats.

  The Journal of surgical research 20100301

• Curcumin decreases the expression of Pokemon by suppressing the binding activity of the Sp1 protein in human lung cancer cells.

  Molecular biology reports 20100301

• Cellular factors involved in CXCL8 expression induced by glycated serum albumin in vascular smooth muscle cells.

  Atherosclerosis 20100301

• Curcumin improves outcomes and attenuates focal cerebral ischemic injury via antiapoptotic mechanisms in rats.

  Neurochemical research 20100301

• Protective effect of curcumin on immune system and body weight gain on rats intoxicated with 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD).

  Immunopharmacology and immunotoxicology 20100301

• Multifocal signal modulation therapy of cancer: ancient weapon, modern targets.

  Molecular and cellular biochemistry 20100301

• Curcumin suppresses p38 mitogen-activated protein kinase activation, reduces IL-1beta and matrix metalloproteinase-3 and enhances IL-10 in the mucosa of children and adults with inflammatory bowel disease.

  The British journal of nutrition 20100301

• Improvement in oxidative stress and antioxidant parameters in beta-thalassemia/Hb E patients treated with curcuminoids.

  Clinical biochemistry 20100301

• Apoptosis by dietary agents for prevention and treatment of prostate cancer.

  Endocrine-related cancer 20100301

• Curcuminoid analogs with potent activity against Trypanosoma and Leishmania species.

  European journal of medicinal chemistry 20100301

• Demethoxycurcumin, a natural derivative of curcumin attenuates LPS-induced pro-inflammatory responses through down-regulation of intracellular ROS-related MAPK/NF-kappaB signaling pathways in N9 microglia induced by lipopolysaccharide.

  International immunopharmacology 20100301

• Curcumin inhibits the Sonic Hedgehog signaling pathway and triggers apoptosis in medulloblastoma cells.

  Molecular carcinogenesis 20100301

• Effect of curcumin on brain insulin receptors and memory functions in STZ (ICV) induced dementia model of rat.

  Pharmacological research 20100301

• Curcumin protects against hyperosmoticity-induced IL-1beta elevation in human corneal epithelial cell via MAPK pathways.

  Experimental eye research 20100301

• Synthesis, antibacterial and antiviral properties of curcumin bioconjugates bearing dipeptide, fatty acids and folic acid.

  European journal of medicinal chemistry 20100301

• Superoxide anion and proteasomal dysfunction contribute to curcumin-induced paraptosis of malignant breast cancer cells.

  Free radical biology & medicine 20100301

• The enhancement of antiproliferative and proapoptotic activity of HDAC inhibitors by curcumin is mediated by Hsp90 inhibition.

  Cellular and molecular life sciences : CMLS 20100301

• Naturally occurring phytochemicals for the prevention of Alzheimer's disease.

  Journal of neurochemistry 20100301

• Binding of curcumin with glyoxalase I: Molecular docking, molecular dynamics simulations, and kinetics analysis.

  Biophysical chemistry 20100301

• Curcumin blocks migration and invasion of mouse-rat hybrid retina ganglion cells (N18) through the inhibition of MMP-2, -9, FAK, Rho A and Rock-1 gene expression.

  Oncology reports 20100301

• The mismatch repair system modulates curcumin sensitivity through induction of DNA strand breaks and activation of G2-M checkpoint.

  Molecular cancer therapeutics 20100301

• Differential inhibition of protein translation machinery by curcumin in normal, immortalized, and malignant oral epithelial cells.

  Cancer prevention research (Philadelphia, Pa.) 20100301

• Targeting tumor proteasome with traditional Chinese medicine.

  Current drug discovery technologies 20100301

• Traditional Chinese medicines (TCMs) for molecular targeted therapies of tumours.

  Current drug discovery technologies 20100301

• Thioredoxin reductase-1 mediates curcumin-induced radiosensitization of squamous carcinoma cells.

  Cancer research 20100301

• Combined treatment of tetrahydrocurcumin and chlorogenic acid exerts potential antihyperglycemic effect on streptozotocin-nicotinamide-induced diabetic rats.

  General physiology and biophysics 20100301

• Prophylactic role of curcumin against cyclosporine-induced nephrotoxicity: histological and immunohistological study.

  General physiology and biophysics 20100301

• Cancer preventive agents 10. Prenylated dehydrozingerone analogs as potent chemopreventive agents.

  Journal of Asian natural products research 20100301

• Evaluation of liposomal curcumin cytochrome p450 metabolism.

  Anticancer research 20100301

• [Evaluation on a fast weight reduction model in vitro].

  Wei sheng yan jiu = Journal of hygiene research 20100301

• Amelioration of tamoxifen-induced liver injury in rats by grape seed extract, black seed extract and curcumin.

  Indian journal of experimental biology 20100301

• Curcumin protects rats against acetaminophen-induced hepatorenal damages and shows synergistic activity with N-acetyl cysteine.

  European journal of pharmacology 20100225

• A synthetic curcuminoid derivative inhibits nitric oxide and proinflammatory cytokine synthesis.

  European journal of pharmacology 20100225

• Safety and pharmacokinetics of a solid lipid curcumin particle formulation in osteosarcoma patients and healthy volunteers.

  Journal of agricultural and food chemistry 20100224

• Curcumin inhibits hepatitis C virus replication via suppressing the Akt-SREBP-1 pathway.

  FEBS letters 20100219

• Rescue of ER oxidoreductase function through polyphenolic phytochemical intervention: implications for subcellular traffic and neurodegenerative disorders.

  Biochemical and biophysical research communications 20100219

• Metabolic intervention of aflatoxin B1 toxicity by curcumin.

  Journal of ethnopharmacology 20100217

• Curcumin prevents free radical-mediated cataractogenesis through modulations in lens calcium.

  Free radical biology & medicine 20100215

• Binding of curcumin and its long chain derivatives to the activator binding domain of novel protein kinase C.

  Bioorganic & medicinal chemistry 20100215

• Expression analysis of maspin in invasive ductal carcinoma of breast and modulation of its expression by curcumin in breast cancer cell lines.

  Chemico-biological interactions 20100212

• Demethoxycurcumin suppresses migration and invasion of MDA-MB-231 human breast cancer cell line.

  European journal of pharmacology 20100210

• Curcumin prevents human aortic smooth muscle cells migration by inhibiting of MMP-9 expression.

  Nutrition, metabolism, and cardiovascular diseases : NMCD 20100201

• Encapsulation of curcumin in alginate-chitosan-pluronic composite nanoparticles for delivery to cancer cells.

  Nanomedicine : nanotechnology, biology, and medicine 20100201

• Lysophosphatidic acid induces STAT3 phosphorylation and ovarian cancer cell motility: their inhibition by curcumin.

  Cancer letters 20100201

• Design of curcumin-loaded PLGA nanoparticles formulation with enhanced cellular uptake, and increased bioactivity in vitro and superior bioavailability in vivo.

  Biochemical pharmacology 20100201

• Synergistic anti-inflammatory effects of low doses of curcumin in combination with polyunsaturated fatty acids: docosahexaenoic acid or eicosapentaenoic acid.

  Biochemical pharmacology 20100201

• Altered profiles of gene expression in curcumin-treated rats with experimentally induced myocardial infarction.

  Pharmacological research 20100201

• Mechanisms involved in ultrafine carbon black-induced release of IL-6 from primary rat epithelial lung cells.

  Toxicology in vitro : an international journal published in association with BIBRA 20100201

• Antihyperlipidemic effect of bis-1,7-(2-hydroxyphenyl)-hepta-1,6-diene-3,5-dione, a curcumin analog, on nicotine and streptozotocin treated rats.

  Molecular and cellular biochemistry 20100201

• Biological actions of curcumin on articular chondrocytes.

  Osteoarthritis and cartilage 20100201

• Inhibitory effect of curcumin on liver injury in a murine model of endotoxemic shock.

  Biotechnology letters 20100201

• Curcumin produces neuroprotective effects via activating brain-derived neurotrophic factor/TrkB-dependent MAPK and PI-3K cascades in rodent cortical neurons.

  Progress in neuro-psychopharmacology & biological psychiatry 20100201

• Partial correction of cystic fibrosis defects with PLGA nanoparticles encapsulating curcumin.

  Molecular pharmaceutics 20100201

• Curcumin reduces angiotensin II-mediated cardiomyocyte growth via LOX-1 inhibition.

  Journal of cardiovascular pharmacology 20100201

• Curcumin produces an antihyperalgesic effect via antagonism of TRPV1.

  Journal of dental research 20100201

• Curcumin induces apoptosis in human lung adenocarcinoma A549 cells through a reactive oxygen species-dependent mitochondrial signaling pathway.

  Oncology reports 20100201

• Structure-activity relationship of C5-curcuminoids and synthesis of their molecular probes thereof.

  Bioorganic & medicinal chemistry 20100201

• Curcumin inhibits human lung large cell carcinoma cancer tumour growth in a murine xenograft model.

  Phytotherapy research : PTR 20100201

• Curcumin inhibits constitutive STAT3 phosphorylation in human pancreatic cancer cell lines and downregulation of survivin/BIRC5 gene expression.

  Cancer investigation 20100201

• Effect of curcumin on selenite-induced cataractogenesis in Wistar rat pups.

  Current eye research 20100201

• [Protective effects of curcumin on neonatal rats with necrotizing enterocolitis].

  Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20100201

• Enhanced fluorescence of curcumin on plasmonic platforms.

  Current pharmaceutical biotechnology 20100201

• Curcumin prevents dopaminergic neuronal death through inhibition of the c-Jun N-terminal kinase pathway.

  Rejuvenation research 20100201

• Curcumin targets FOLFOX-surviving colon cancer cells via inhibition of EGFRs and IGF-1R.

  Anticancer research 20100201

• Curcumin (diferuloylmethane) induces apoptosis and blocks migration of human medulloblastoma cells.

  Anticancer research 20100201

• [Anticancer activities of curcumin on human hepatocarcinoma cell line Sk-hep-1].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100201

• Effect of curcumin and ferulic acid on modulation of expression pattern of p53 and bcl-2 proteins in 7,12-dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis.

  Indian journal of biochemistry & biophysics 20100201

• Effect of curcumin on vascular endothelial growth factor expression in diabetic mice kidney induced by streptozotocin.

  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20100201

• Expression of hepatic antioxidant genes in l-thyroxine-induced hyperthyroid rats: regulation by vitamin E and curcumin.

  Chemico-biological interactions 20100127

• Protective effect of curcumin against intracerebral streptozotocin induced impairment in memory and cerebral blood flow.

  Life sciences 20100116

• Curcumin potentiates the antitumor effects of gemcitabine in an orthotopic model of human bladder cancer through suppression of proliferative and angiogenic biomarkers.

  Biochemical pharmacology 20100115

• Curcumin pretreatment protects against acute acrylonitrile-induced oxidative damage in rats.

  Toxicology 20100112

• Curcumin exposure induces expression of the Parkinson's disease-associated leucine-rich repeat kinase 2 (LRRK2) in rat mesencephalic cells.

  Neuroscience letters 20100104

• Curcumin delays development of medroxyprogesterone acetate-accelerated 7,12-dimethylbenz[a]anthracene-induced mammary tumors.

  Menopause (New York, N.Y.) 20100101

• Curcumin-induced apoptosis in ovarian carcinoma cells is p53-independent and involves p38 mitogen-activated protein kinase activation and downregulation of Bcl-2 and survivin expression and Akt signaling.

  Molecular carcinogenesis 20100101

• Curcumin inhibits phorbol myristate acetate (PMA)-induced MCP-1 expression by inhibiting ERK and NF-kappaB transcriptional activity.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100101

• Requirement for nuclear factor kappa B signalling in the interleukin-1-induced expression of the CCAAT/enhancer binding protein-delta gene in hepatocytes.

  The international journal of biochemistry & cell biology 20100101

• RIP4 is a target of multiple signal transduction pathways in keratinocytes: implications for epidermal differentiation and cutaneous wound repair.

  Experimental cell research 20100101

• Combination of curcumin and green tea catechins prevents dimethylhydrazine-induced colon carcinogenesis.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100101

• Phase I dose escalation trial of docetaxel plus curcumin in patients with advanced and metastatic breast cancer.

  Cancer biology & therapy 20100101

• Curcumin limits the fibrogenic evolution of experimental steatohepatitis.

  Laboratory investigation; a journal of technical methods and pathology 20100101

• Thioredoxin system modulation by plant and fungal secondary metabolites.

  Current medicinal chemistry 20100101

• Curcumin attenuates glucose-induced monocyte chemoattractant protein-1 synthesis in aortic endothelial cells by modulating the nuclear factor-kappaB pathway.

  Pharmacology 20100101

• Novel enoyl-ACP reductase (FabI) potential inhibitors of Escherichia coli from Chinese medicine monomers.

  Bioorganic & medicinal chemistry letters 20100101

• Neuroprotective effects of naturally occurring polyphenols on quinolinic acid-induced excitotoxicity in human neurons.

  The FEBS journal 20100101

• Dose-dependent actions of curcumin in experimentally induced myocardial necrosis: a biochemical, histopathological, and electron microscopic evidence.

  Cell biochemistry and function 20100101

• Novel aspects for the application of Curcumin in chemoprevention of various cancers.

  Frontiers in bioscience (Scholar edition) 20100101

• [Inhibiting effect of letrozole combined with curcumin on xenografted endometrial carcinoma growth in nude mice].

  Chinese journal of cancer 20100101

• Inhibitory effect of curcumin on IMP dehydrogenase, the target for anticancer and antiviral chemotherapy agents.

  Bioscience, biotechnology, and biochemistry 20100101

• A new target for amyloid beta toxicity validated by standard and high-throughput electrophysiology.

  PloS one 20100101

• Assessing the neuroprotective effect of antioxidant food factors by application of lipid-derived dopamine modification adducts.

  Methods in molecular biology (Clifton, N.J.) 20100101

• Possible benefits of curcumin regimen in combination with taxane chemotherapy for hormone-refractory prostate cancer treatment.

  Nutrition and cancer 20100101

• Effects of dietary ingredients on function and expression of P-glycoprotein in human intestinal epithelial cells.

  Biological & pharmaceutical bulletin 20100101

• Curcumin and saikosaponin a inhibit chemical-induced liver inflammation and fibrosis in rats.

  The American journal of Chinese medicine 20100101

• Curcumin inhibits GPVI-mediated platelet activation by interfering with the kinase activity of Syk and the subsequent activation of PLCgamma2.

  Platelets 20100101

• Curcumin inhibits the growth, induces apoptosis and modulates the function of pituitary folliculostellate cells.

  Neuroendocrinology 20100101

• Curcumin inhibits transforming growth factor-beta activity via inhibition of Smad signaling in HK-2 cells.

  American journal of nephrology 20100101

• Comparison and prediction of the retention in micellar electrokinetic chromatography and microemulsion electrokinetic chromatography for disubstituted benzenes.

  Electrophoresis 20100101

• [Reducing effect of curcumin on expressions of TNF-alpha, IL-6 and IL-8 in rats with chronic nonbacterial prostatitis].

  Zhonghua nan ke xue = National journal of andrology 20100101

• 4'-O-methylglycosylation of curcumin by Beauveria bassiana.

  Natural product communications 20100101

• Antiangogenic effect of selected phytochemicals.

  Die Pharmazie 20100101

• Precursor-directed biosynthesis of curcumin analogs in Escherichia coli.

  Bioscience, biotechnology, and biochemistry 20100101

• Curcumin as an anti-cancer agent: review of the gap between basic and clinical applications.

  Current medicinal chemistry 20100101

• Curcumin and turmeric attenuate arsenic-induced angiogenesis in ovo.

  Alternative therapies in health and medicine 20100101

• Dietary polyphenols affect MUC5AC expression and ciliary movement in respiratory cells and nasal mucosa.

  American journal of rhinology & allergy 20100101

• Consumption of curcumin elevates fecal immunoglobulin A, an index of intestinal immune function, in rats fed a high-fat diet.

  Journal of nutritional science and vitaminology 20100101

• Curcumin-induced apoptosis in PC3 prostate carcinoma cells is caspase-independent and involves cellular ceramide accumulation and damage to mitochondria.

  Nutrition and cancer 20100101

• Therapeutic efficacy evaluation of curcumin on human oral squamous cell carcinoma xenograft using multimodalities of molecular imaging.

  The American journal of Chinese medicine 20100101

• The promise of slow down ageing may come from curcumin.

  Current pharmaceutical design 20100101

• [Progress of research on microRNA in gastrointestinal cancer].

  Zhonghua bing li xue za zhi = Chinese journal of pathology 20100101

• Efficacy of curcumin to reduce hepatic damage induced by alcohol and thermally treated oil in rats.

  Veterinaria italiana 20100101

• Curcumin inhibits cholesterol uptake in Caco-2 cells by down-regulation of NPC1L1 expression.

  Lipids in health and disease 20100101

• Growth suppression of mouse pituitary corticotroph tumor AtT20 cells by curcumin: a model for treating Cushing's disease.

  PloS one 20100101

• PPARgamma agonist curcumin reduces the amyloid-beta-stimulated inflammatory responses in primary astrocytes.

  Journal of Alzheimer's disease : JAD 20100101

• Severe motor neuron degeneration in the spinal cord of the Tg2576 mouse model of Alzheimer disease.

  Journal of Alzheimer's disease : JAD 20100101

• Curcumin reduces alpha-synuclein induced cytotoxicity in Parkinson's disease cell model.

  BMC neuroscience 20100101

• Evaluation of in vitro anti-proliferative and immunomodulatory activities of compounds isolated from Curcuma longa.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100101

• Toxicological evaluation of pH-sensitive nanoparticles of curcumin: acute, sub-acute and genotoxicity studies.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100101

• Bioavailability and delivery of nutraceuticals using nanotechnology.

  Journal of food science 20100101

• Redox modulation and human bile duct cancer inhibition by curcumin.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100101

• Curcumin modulates dopaminergic receptor, CREB and phospholipase C gene expression in the cerebral cortex and cerebellum of streptozotocin induced diabetic rats.

  Journal of biomedical science 20100101

• [Studies on preparation and dissolution test in vitro of sustained-release dropping pills of curcumin].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20100101

• Enhanced anti-tumor activity of a new curcumin-related compound against melanoma and neuroblastoma cells.

  Molecular cancer 20100101

• Synergistic effect of curcumin and insulin on muscle cell glucose metabolism.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100101

• The small molecule curcumin analog FLLL32 induces apoptosis in melanoma cells via STAT3 inhibition and retains the cellular response to cytokines with anti-tumor activity.

  Molecular cancer 20100101

• Cross-linking of ΔF508-CFTR promotes its trafficking to the plasma membrane.

  Channels (Austin, Tex.) 20100101

• Indian spice curcumin may be an effective strategy to combat the genotoxicity of arsenic in Swiss albino mice.

  Asian Pacific journal of cancer prevention : APJCP 20100101

• Curcumin mediated suppression of nuclear factor-κB promotes chondrogenic differentiation of mesenchymal stem cells in a high-density co-culture microenvironment.

  Arthritis research & therapy 20100101

• A new cyclooxygenase-2 inhibitor, (1E,4E)-1,5-bis(2-bromophenyl)penta-1,4-dien-3-one (GL63) suppresses cyclooxygenase-2 gene expression in human lung epithelial cancer cells: coupled mRNA stabilization and posttranscriptional inhibition.

  Biological & pharmaceutical bulletin 20100101

• Curcumin increases the pathogenicity of Salmonella enterica serovar Typhimurium in murine model.

  PloS one 20100101

• Effect of curcumin and Meriva on the lung metastasis of murine mammary gland adenocarcinoma.

  In vivo (Athens, Greece) 20100101

• Apoptosis of human lung cancer cells by curcumin mediated through up-regulation of 'growth arrest and DNA damage inducible genes 45 and 153'.

  Biological & pharmaceutical bulletin 20100101

• A novel small molecule inhibits STAT3 phosphorylation and DNA binding activity and exhibits potent growth suppressive activity in human cancer cells.

  Molecular cancer 20100101

• Resveratrol differentially modulates inflammatory responses of microglia and astrocytes.

  Journal of neuroinflammation 20100101

• Nicotine-induced survival signaling in lung cancer cells is dependent on their p53 status while its down-regulation by curcumin is independent.

  Molecular cancer 20100101

• Anti-breast cancer activity of curcumin on the human oxidation-resistant cells ZR-75-1 with gamma-glutamyltranspeptidase inhibition.

  Journal of experimental therapeutics & oncology 20100101

• Reference profile correlation reveals estrogen-like trancriptional activity of Curcumin.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20100101

• The potential influence of plant polyphenols on the aging process.

  Forschende Komplementarmedizin (2006) 20100101

• Curcumin Inhibits the proteinase-activated receptor-2-triggered prostaglandin E2 production by suppressing cyclooxygenase-2 upregulation and Akt-dependent activation of nuclear factor-κB in human lung epithelial cells.

  Journal of pharmacological sciences 20100101

• The nontoxic natural compound Curcumin exerts anti-proliferative, anti-migratory, and anti-invasive properties against malignant gliomas.

  BMC cancer 20100101

• Curcumin protects intestinal mucosal barrier function of rat enteritis via activation of MKP-1 and attenuation of p38 and NF-κB activation.

  PloS one 20100101

• Curcumin, the golden spice from Indian saffron, is a chemosensitizer and radiosensitizer for tumors and chemoprotector and radioprotector for normal organs.

  Nutrition and cancer 20100101

• Colorectal cancer: chemopreventive role of curcumin and resveratrol.

  Nutrition and cancer 20100101

• Chemopreventive potential of natural compounds in head and neck cancer.

  Nutrition and cancer 20100101

• Conundrum and therapeutic potential of curcumin in drug delivery.

  Critical reviews in therapeutic drug carrier systems 20100101

• Curcumin supplementation could improve diabetes-induced endothelial dysfunction associated with decreased vascular superoxide production and PKC inhibition.

  BMC complementary and alternative medicine 20100101

• [Effect of NF-kappaB activation inhibitor curcumin on the oogenesis and follicular cell death in immune ovarian failure in mice].

  Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20100101

• Assessment of phosphamidon-induced apoptosis in human peripheral blood mononuclear cells: protective effects of N-acetylcysteine and curcumin.

  Journal of biochemical and molecular toxicology 20100101

• Curcumin and gemcitabine in patients with advanced pancreatic cancer.

  Nutrition and cancer 20100101

• Curcumin facilitates fibrinolysis and cellular migration during wound healing by modulating urokinase plasminogen activator expression.

  Pathophysiology of haemostasis and thrombosis 20100101

• Curcumin activates the p38MPAK-HSP25 pathway in vitro but fails to attenuate diabetic nephropathy in DBA2J mice despite urinary clearance documented by HPLC.

  BMC complementary and alternative medicine 20100101

• Effects of curcumin on the skeletal system in rats.

  Pharmacological reports : PR 20100101

• Formulation of a medical food cocktail for Alzheimer's disease: beneficial effects on cognition and neuropathology in a mouse model of the disease.

  PloS one 20100101

• Reversal of hypermethylation and reactivation of the RARβ2 gene by natural compounds in cervical cancer cell lines.

  Folia biologica 20100101

• Anti-inflammatory effects of resveratrol, curcumin and simvastatin in acute small intestinal inflammation.

  PloS one 20100101

• Hazardous effects of curcumin on mouse embryonic development through a mitochondria-dependent apoptotic signaling pathway.

  International journal of molecular sciences 20100101

• Urine and serum analysis of consumed curcuminoids using an IkappaB-luciferase surrogate marker assay.

  In vivo (Athens, Greece) 20100101

• Prevention of sodium valproate-induced hepatotoxicity by curcumin, rosiglitazone and N-acetylcysteine in rats.

  Arzneimittel-Forschung 20100101

• [Effect of curcumin on nitric oxide induced structural and functional modifications of high molecular weight cystatin from the goat brain].

  Biomeditsinskaia khimiia 20100101

• Effects of curcumin on the intestinal motility of albino rats.

  Indian journal of physiology and pharmacology 20100101

• Therapeutic potential of dietary polyphenols against brain ageing and neurodegenerative disorders.

  Advances in experimental medicine and biology 20100101

• Comparison of anti-inflammatory and anti-nociceptive activities of Curcuma wenyujin Y.H. Chen et C. Ling and Scutellaria baicalensis Georgi.

  African journal of traditional, complementary, and alternative medicines : AJTCAM 20100101

• Curcumin-the paradigm of a multi-target natural compound with applications in cancer prevention and treatment.

  Toxins 20100101

• Protective effect of curcumin (Curcuma longa), against aluminium toxicity: Possible behavioral and biochemical alterations in rats.

  Behavioural brain research 20091228

• Cytotoxic activity of curcumin towards CCRF-CEM leukemia cells and its effect on DNA damage.

  Molecules (Basel, Switzerland) 20091217

• Curcumin! Spicy panacea for all--friend or foe.

  Vaccine 20091211

• Curcumin is protective against phenytoin-induced cognitive impairment and oxidative stress in rats.

  Brain research 20091208

• Curcumin-loaded poly(epsilon-caprolactone) nanofibres: diabetic wound dressing with anti-oxidant and anti-inflammatory properties.

  Clinical and experimental pharmacology & physiology 20091201

• Curcumin ameliorates high glucose-induced acute vascular endothelial dysfunction in rat thoracic aorta.

  Clinical and experimental pharmacology & physiology 20091201

• Effects of a turmeric extract (Curcuma longa) on chronic ultraviolet B irradiation-induced skin damage in melanin-possessing hairless mice.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20091201

• Curcumin inhibits pro-inflammatory mediators and metalloproteinase-3 production by chondrocytes.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20091201

• Hepatoprotective activity of picroliv, curcumin and ellagic acid compared to silymarin on paracetamol induced liver toxicity in mice.

  Fundamental & clinical pharmacology 20091201

• Antioxidant efficacy of curcuminoids from turmeric ( Curcuma longa L.) powder in broiler chickens fed diets containing aflatoxin B1.

  The British journal of nutrition 20091201

• Optimized turmeric extracts have potent anti-amyloidogenic effects.

  Current Alzheimer research 20091201

• Curcumin acts as anti-tumorigenic and hormone-suppressive agent in murine and human pituitary tumour cells in vitro and in vivo.

  Endocrine-related cancer 20091201

• Modulation of aflatoxin B1-mediated genotoxicity in primary cultures of human hepatocytes by diindolylmethane, curcumin, and xanthohumols.

  Toxicological sciences : an official journal of the Society of Toxicology 20091201

• Multifunctional role of VIP in prostate cancer progression in a xenograft model: suppression by curcumin and COX-2 inhibitor NS-398.

  Peptides 20091201

• An anticancer effect of curcumin mediated by down-regulating phosphatase of regenerating liver-3 expression on highly metastatic melanoma cells.

  Molecular pharmacology 20091201

• Curcumin inhibits srebp-2 expression in activated hepatic stellate cells in vitro by reducing the activity of specificity protein-1.

  Endocrinology 20091201

• Curcumin attenuates the effects of insulin on stimulating hepatic stellate cell activation by interrupting insulin signaling and attenuating oxidative stress.

  Laboratory investigation; a journal of technical methods and pathology 20091201

• Curcumin analog cytotoxicity against breast cancer cells: exploitation of a redox-dependent mechanism.

  Bioorganic & medicinal chemistry letters 20091201

• Modulation of activation-induced cytidine deaminase by curcumin in Helicobacter pylori-infected gastric epithelial cells.

  Helicobacter 20091201

• Phenolic compounds prevent Alzheimer's pathology through different effects on the amyloid-beta aggregation pathway.

  The American journal of pathology 20091201

• Curcumin potentiates the antitumor effects of Bacillus Calmette-Guerin against bladder cancer through the downregulation of NF-kappaB and upregulation of TRAIL receptors.

  Cancer research 20091201

• Effects of turmeric (Curcuma longa) on the expression of hepatic genes associated with biotransformation, antioxidant, and immune systems in broiler chicks fed aflatoxin.

  Poultry science 20091201

• Monocyte/macrophage androgen receptor suppresses cutaneous wound healing in mice by enhancing local TNF-alpha expression.

  The Journal of clinical investigation 20091201

• Effect of curcumin on the proliferation and apoptosis of hepatic stellate cells.

  Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20091201

• Assessment of antichlamydial effects of a novel polyherbal tablet Basant.

  Sexually transmitted infections 20091201

• Modification of pharmacokinetics of norfloxacin following oral administration of curcumin in rabbits.

  Journal of veterinary science 20091201

• Reduced expression of ATP7B affected by Wilson disease-causing mutations is rescued by pharmacological folding chaperones 4-phenylbutyrate and curcumin.

  Hepatology (Baltimore, Md.) 20091201

• Hepatocyte nuclear factor-4-independent synthesis of coagulation factor VII in breast cancer cells and its inhibition by targeting selective histone acetyltransferases.

  Molecular cancer research : MCR 20091201

• Curcumin induces cell cycle arrest and apoptosis in human osteosarcoma (HOS) cells.

  Anticancer research 20091201

• Inhibitory effects of curcuminoids on passive cutaneous anaphylaxis reaction and scratching behavior in mice.

  Archives of pharmacal research 20091201

• Curcumin, piperine could play role in preventing breast cancer.

  Cancer biology & therapy 20091201

• [Effect of curcumin on growth and function of fibroblast in human hyperplastic scar].

  Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20091201

• [Preparation and in vitro release characteristics of curcumin loaded biodegradable microspheres].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20091201

• Anti-ulcer activity of curcumin on experimental gastric ulcer in rats and its effect on oxidative stress/antioxidant, IL-6 and enzyme activities.

  Biomedical and environmental sciences : BES 20091201

• [Neuroprotective effects of curcumin].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20091201

• [Effect of curcumin on JAK-STAT signaling pathway in hepatoma cell lines].

  Yao xue xue bao = Acta pharmaceutica Sinica 20091201

• Study on the antibiotic activity of microcapsule curcumin against foodborne pathogens.

  International journal of food microbiology 20091130

• Curcumin inhibits the migration and invasion of human A549 lung cancer cells through the inhibition of matrix metalloproteinase-2 and -9 and Vascular Endothelial Growth Factor (VEGF).

  Cancer letters 20091128

• Phenolic and enolic hydroxyl groups in curcumin: which plays the major role in scavenging radicals?

  Journal of agricultural and food chemistry 20091125

• Activation of muscarinic M-1 cholinoceptors by curcumin to increase glucose uptake into skeletal muscle isolated from Wistar rats.

  Neuroscience letters 20091120

• Inhibition of aldose reductase by dietary antioxidant curcumin: mechanism of inhibition, specificity and significance.

  FEBS letters 20091119

• Effects of curcumin for preventing restenosis in a hypercholesterolemic rabbit iliac artery stent model.

  Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20091115

• Curcumin derivatives: molecular basis of their anti-cancer activity.

  Biochemical pharmacology 20091115

• Contribution of degradation products to the anticancer activity of curcumin.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20091115

• Interaction of alphaS1-casein with curcumin and its biological implications.

  Journal of agricultural and food chemistry 20091111

• Studies on curcumin and curcuminoids. XXXIV. Photophysical properties of a symmetrical, non-substituted curcumin analogue.

  Journal of photochemistry and photobiology. B, Biology 20091109

• Potent and selective inhibition of the tumor marker AKR1B10 by bisdemethoxycurcumin: probing the active site of the enzyme with molecular modeling and site-directed mutagenesis.

  Biochemical and biophysical research communications 20091106

• Uncoupling of oxidative phosphorylation by curcumin: implication of its cellular mechanism of action.

  Biochemical and biophysical research communications 20091106

• Curcumin cross-links cystic fibrosis transmembrane conductance regulator (CFTR) polypeptides and potentiates CFTR channel activity by distinct mechanisms.

  The Journal of biological chemistry 20091106

• Neuroprotective role of curcumin in the cerebellum of streptozotocin-induced diabetic rats.

  Life sciences 20091104

• Curcumin induces apoptosis-independent death in oesophageal cancer cells.

  British journal of cancer 20091103

• In vitro modulation of TCF7L2 gene expression in human pancreatic cells.

  Molecular biology reports 20091101

• Cellular signaling perturbation by natural products.

  Cellular signalling 20091101

• Prevention of nicotine and streptozotocin treatment induced circulatory oxidative stress by bis-1,7-(2-hydroxyphenyl)-hepta-1,6-diene-3,5-dione in diabetic rats.

  Molecular and cellular biochemistry 20091101

• A rapid and simple HPLC method for the determination of curcumin in rat plasma: assay development, validation and application to a pharmacokinetic study of curcumin liposome.

  Biomedical chromatography : BMC 20091101

• Curcumin prevents the oxidation and lipid modification of LDL and its inhibition of prostacyclin generation by endothelial cells in culture.

  Prostaglandins & other lipid mediators 20091101

• Curcumin sensitizes human colorectal cancer to capecitabine by modulation of cyclin D1, COX-2, MMP-9, VEGF and CXCR4 expression in an orthotopic mouse model.

  International journal of cancer 20091101

• Attenuation of arsenic neurotoxicity by curcumin in rats.

  Toxicology and applied pharmacology 20091101

• Curcumin enhances paraquat-induced apoptosis of N27 mesencephalic cells via the generation of reactive oxygen species.

  Neurotoxicology 20091101

• Harnessing the fruits of nature for the development of multi-targeted cancer therapeutics.

  Cancer treatment reviews 20091101

• Curcumin reduced the side effects of mitomycin C by inhibiting GRP58-mediated DNA cross-linking in MCF-7 breast cancer xenografts.

  Cancer science 20091101

• Fluorocurcumins as cyclooxygenase-2 inhibitor: molecular docking, pharmacokinetics and tissue distribution in mice.

  Pharmaceutical research 20091101

• Curcumin eliminates oxidized LDL roles in activating hepatic stellate cells by suppressing gene expression of lectin-like oxidized LDL receptor-1.

  Laboratory investigation; a journal of technical methods and pathology 20091101

• Curcumin inhibits COPD-like airway inflammation and lung cancer progression in mice.

  Carcinogenesis 20091101

• Insights into the inhibition of xanthine oxidase by curcumin.

  Bioorganic & medicinal chemistry letters 20091101

• Pharmacological actions of curcumin in liver diseases or damage.

  Liver international : official journal of the International Association for the Study of the Liver 20091101

• Synthesis and biological evaluation of clicked curcumin and clicked KLVFFA conjugates as inhibitors of beta-amyloid fibril formation.

  Bioconjugate chemistry 20091101

• Curcumin induces the tolerogenic dendritic cell that promotes differentiation of intestine-protective regulatory T cells.

  European journal of immunology 20091101

• Haem oxygenase-1 induction protects against tumour necrosis factor alpha impairment of endothelial-dependent relaxation in rat isolated pulmonary artery.

  British journal of pharmacology 20091101

• Inside lab invest.

  Laboratory investigation; a journal of technical methods and pathology 20091101

• Curcumin nutrition for the prevention of mesenteric ischemia-reperfusion injury: an experimental rodent model.

  Transplantation proceedings 20091101

• [Curcumine inhibits migration and invasion of hepatic stellate cells by reducing MMP-2 expression and activity].

  Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20091101

• The arylhydrocarbon receptor is only marginally involved in the antileukemic effects of its ligand curcumin.

  Anticancer research 20091101

• Increased pro-inflammatory activity and impairment of human monocyte differentiation induced by in vitro exposure to cigarette smoke.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20091101

• Autophagic and apoptotic mechanisms of curcumin-induced death in K562 cells.

  Journal of Asian natural products research 20091101

• [Pharmacological researches of curcumin solid dispersions on experimental gastric ulcer].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20091101

• Effect of curcumin on pathogenesis of hamster-opisthorchiasis through apoptosis-related gene expression.

  The Southeast Asian journal of tropical medicine and public health 20091101

• Gastroprotective effects of a new zinc(II)-curcumin complex against pylorus-ligature-induced gastric ulcer in rats.

  Chemico-biological interactions 20091030

• Design, synthesis, and testing of difluoroboron-derivatized curcumins as near-infrared probes for in vivo detection of amyloid-beta deposits.

  Journal of the American Chemical Society 20091028

• Curcumin suppresses increased bone resorption by inhibiting osteoclastogenesis in rats with streptozotocin-induced diabetes.

  European journal of pharmacology 20091025

• Interleukin-1 inhibits Sox9 and collagen type II expression via nuclear factor-kappaB in the cultured human intervertebral disc cells.

  Chinese medical journal 20091020

• Curcumin activates AMPK and suppresses gluconeogenic gene expression in hepatoma cells.

  Biochemical and biophysical research communications 20091016

• Preparation and in vitro release profiles of drug-eluting controlled biodegradable polymer coating stents.

  Colloids and surfaces. B, Biointerfaces 20091015

• Oral administration of heat-solubilized curcumin for potentially increasing curcumin bioavailability in experimental animals.

  International journal of cancer 20091015

• Evaluation of an oral carrier system in rats: bioavailability and antioxidant properties of liposome-encapsulated curcumin.

  Journal of agricultural and food chemistry 20091014

• Anti-cataractogenic effect of curcumin and aminoguanidine against selenium-induced oxidative stress in the eye lens of Wistar rat pups: An in vitro study using isolated lens.

  Chemico-biological interactions 20091007

• Potent growth suppressive activity of curcumin in human breast cancer cells: Modulation of Wnt/beta-catenin signaling.

  Chemico-biological interactions 20091007

• Potential protection of curcumin against amyloid beta-induced toxicity on cultured rat prefrontal cortical neurons.

  Neuroscience letters 20091002

• Treatment of HIV-associated diarrhea with curcumin.

  Digestive diseases and sciences 20091001

• Novel artemisinin and curcumin micellar formulations: drug solubility studies by NMR spectroscopy.

  Journal of pharmaceutical sciences 20091001

• Synthesis and characterization of glucosyl-curcuminoids as Fe3+ suppliers in the treatment of iron deficiency.

  Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20091001

• Genistein and curcumin suppress epidermal growth factor-induced MUC5AC mucin production and gene expression from human airway epithelial cells.

  Phytotherapy research : PTR 20091001

• Modulation of in vitro murine B-lymphocyte response by curcumin.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20091001

• Attenuation of proteolysis and muscle wasting by curcumin c3 complex in MAC16 colon tumour-bearing mice.

  The British journal of nutrition 20091001

• Curcumin inhibits cell proliferation of MDA-MB-231 and BT-483 breast cancer cells mediated by down-regulation of NFkappaB, cyclinD and MMP-1 transcription.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20091001

• Curcumin ameliorates rabbits's steatohepatitis via respiratory chain, oxidative stress, and TNF-alpha.

  Free radical biology & medicine 20091001

• Curcumin prevents liver fibrosis by inducing apoptosis and suppressing activation of hepatic stellate cells.

  Journal of natural medicines 20091001

• Effects of curcumin on Cryptosporidium parvum in vitro.

  Parasitology research 20091001

• Effect of curcumin on amyloidogenic property of molten globule-like intermediate state of 2,5-diketo-D-gluconate reductase A.

  Biological chemistry 20091001

• In vitro antifilarial activity of glutathione S-transferase inhibitors.

  Parasitology research 20091001

• Structure elucidation and NMR assignments for curcuminoids from the rhizomes of Curcuma longa.

  Magnetic resonance in chemistry : MRC 20091001

• Role of HSP27 and reduced glutathione in modulating malathion-induced apoptosis of human peripheral blood mononuclear cells: ameliorating effect of N-acetylcysteine and curcumin.

  Toxicology in vitro : an international journal published in association with BIBRA 20091001

• Turmeric reduces inflammatory cells in hamster opisthorchiasis.

  Parasitology research 20091001

• Curcumin: a potential radio-enhancer in head and neck cancer.

  The Laryngoscope 20091001

• Novel anti-prostate cancer curcumin analogues that enhance androgen receptor degradation activity.

  Anti-cancer agents in medicinal chemistry 20091001

• Regulatory roles of beta-catenin and AP-1 on osteoprotegerin production in interleukin-1alpha-stimulated periodontal ligament cells.

  Oral microbiology and immunology 20091001

• Curcumin analogue GO-Y030 inhibits STAT3 activity and cell growth in breast and pancreatic carcinomas.

  International journal of oncology 20091001

• Curcumin modulates the radiosensitivity of colorectal cancer cells by suppressing constitutive and inducible NF-kappaB activity.

  International journal of radiation oncology, biology, physics 20091001

• Effect of oral curcumin on Déjérine-Sottas disease.

  Pediatric neurology 20091001

• Curcumin reduces oxidative and nitrative DNA damage through balancing of oxidant-antioxidant status in hamsters infected with Opisthorchis viverrini.

  Molecular nutrition & food research 20091001

• The thioflavin T fluorescence assay for amyloid fibril detection can be biased by the presence of exogenous compounds.

  The FEBS journal 20091001

• Aromatase inhibitor letrozole in synergy with curcumin in the inhibition of xenografted endometrial carcinoma growth.

  International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20091001

• Formulation, characterization and evaluation of curcumin-loaded PLGA nanospheres for cancer therapy.

  Anticancer research 20091001

• Effect of curcumin on lung resistance-related protein (LRP) in retinoblastoma cells.

  Current eye research 20091001

• Photokilling of bacteria by curcumin in different aqueous preparations. Studies on curcumin and curcuminoids XXXVII.

  Die Pharmazie 20091001

• [Effect of p21-targeted shRNA on curcumin-induced apoptosis of human hepatoma Huh7 cells].

  Yao xue xue bao = Acta pharmaceutica Sinica 20091001

• Curcumin loaded pH-sensitive nanoparticles for the treatment of colon cancer.

  Journal of biomedical nanotechnology 20091001

• Curcumin inhibits cellular condensation and alters microfilament organization during chondrogenic differentiation of limb bud mesenchymal cells.

  Experimental & molecular medicine 20090930

• Consumption of some polyphenols reduces fecal deoxycholic acid and lithocholic acid, the secondary bile acids of risk factors of colon cancer.

  Journal of agricultural and food chemistry 20090923

• Bioactive compounds: historical perspectives, opportunities, and challenges.

  Journal of agricultural and food chemistry 20090923

• N-terminal aliphatic residues dictate the structure, stability, assembly, and small molecule binding of the coiled-coil region of cartilage oligomeric matrix protein.

  Biochemistry 20090915

• The potential role of curcumin in patients with monoclonal gammopathy of undefined significance--its effect on paraproteinemia and the urinary N-telopeptide of type I collagen bone turnover marker.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20090915

• Lack of nucleophilic addition in the isoxazole and pyrazole diketone modified analogs of curcumin; implications for their antitumor and chemosensitizing activities.

  Chemico-biological interactions 20090914

• Design and synthesis of androgen receptor antagonists with bulky side chains for overcoming antiandrogen resistance.

  Journal of medicinal chemistry 20090910

• Anti-inflammatory effects of the roots of Alpinia pricei Hayata and its phenolic compounds.

  Journal of agricultural and food chemistry 20090909

• Identification and characterization of multiple curcumin synthases from the herb Curcuma longa.

  FEBS letters 20090903

• Antioxidative effects of curcumin and its analogues against the free-radical-induced peroxidation of linoleic acid in micelles.

  Phytotherapy research : PTR 20090901

• Inhibition of LPS-induced production of inflammatory factors in the macrophages by mono-carbonyl analogues of curcumin.

  Journal of cellular and molecular medicine 20090901

• Curcumin prevents diabetes-associated abnormalities in the kidneys by inhibiting p300 and nuclear factor-kappaB.

  Nutrition (Burbank, Los Angeles County, Calif.) 20090901

• Amelioration of cognitive deficits and neurodegeneration by curcumin in rat model of sporadic dementia of Alzheimer's type (SDAT).

  European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20090901

• Metabolite analysis in Curcuma domestica using various GC-MS and LC-MS separation and detection techniques.

  Biomedical chromatography : BMC 20090901

• Re: Serenoa repens associated with Urtica dioica (ProstaMEV) and curcumin and quercitin (FlogMEV) extracts are able to improve the efficacy of prulifloxacin in bacterial prostatitis patients: results from a prospective randomised study.

  International journal of antimicrobial agents 20090901

• Curcumin protects neuronal cells from Japanese encephalitis virus-mediated cell death and also inhibits infective viral particle formation by dysregulation of ubiquitin-proteasome system.

  Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 20090901

• Bubbling hookah smoke through heat-solubilized curcumin/turmeric and incorporation of the curry spice as an additive or filter in cigarettes to minimize tobacco smoke-related toxicants.

  Medical hypotheses 20090901

• Arecoline-stimulated connective tissue growth factor production in human buccal mucosal fibroblasts: Modulation by curcumin.

  Oral oncology 20090901

• New synthetic glucosyl-curcuminoids, and their (1)H and (13)C NMR characterization, from Curcuma longa L.

  Plant foods for human nutrition (Dordrecht, Netherlands) 20090901

• Effect of cyclodextrin complexation of curcumin on its solubility and antiangiogenic and anti-inflammatory activity in rat colitis model.

  AAPS PharmSciTech 20090901

• Systemic delivery of curcumin: 21st century solutions for an ancient conundrum.

  Current drug discovery technologies 20090901

• Diferuloylmethane augments the cytotoxic effects of piplartine isolated from Piper chaba.

  Toxicology in vitro : an international journal published in association with BIBRA 20090901

• Efficacy of curcuminoids in alleviation of iron overload and lipid peroxidation in thalassemic mice.

  Medicinal chemistry (Shariqah (United Arab Emirates)) 20090901

• Curcumin reverses impaired cognition and neuronal plasticity induced by chronic stress.

  Neuropharmacology 20090901

• New curcumin analogues exhibit enhanced growth-suppressive activity and inhibit AKT and signal transducer and activator of transcription 3 phosphorylation in breast and prostate cancer cells.

  Cancer science 20090901

• Curcumin and cancer cells: how many ways can curry kill tumor cells selectively?

  The AAPS journal 20090901

• Effect of curcumin on the amyloid fibrillogenesis of hen egg-white lysozyme.

  Biophysical chemistry 20090901

• Inhibition of p300 and nuclear factor-kappaB by curcumin and its role in diabetic nephropathy.

  Nutrition (Burbank, Los Angeles County, Calif.) 20090901

• Curcumin induces proapoptotic effects against human melanoma cells and modulates the cellular response to immunotherapeutic cytokines.

  Molecular cancer therapeutics 20090901

• Oral administration of curcumin suppresses production of matrix metalloproteinase (MMP)-1 and MMP-3 to ameliorate collagen-induced arthritis: inhibition of the PKCdelta/JNK/c-Jun pathway.

  Journal of pharmacological sciences 20090901

• [Anti-opioid action of glutamate-NMDA receptor systems underlying morphine analgesic tolerance].

  Masui. The Japanese journal of anesthesiology 20090901

• Safety and toxicological evaluation of demethylatedcurcuminoids; a novel standardized curcumin product.

  Toxicology mechanisms and methods 20090901

• Bioavailability and activity of phytosome complexes from botanical polyphenols: the silymarin, curcumin, green tea, and grape seed extracts.

  Alternative medicine review : a journal of clinical therapeutic 20090901

• [The inhibitory effect of curcumin on the proliferation of HT-29 colonic cancer cell induced by deoxycholic acid].

  Zhonghua nei ke za zhi 20090901

• Curcumin improves vascular function and alleviates oxidative stress in non-lethal lipopolysaccharide-induced endotoxaemia in mice.

  European journal of pharmacology 20090815

• Curcumin analogue inhibits lipid peroxidation in a freshwater teleost, Anabas testudineus (Bloch)--an in vitro and in vivo study.

  Fish physiology and biochemistry 20090801

• Curcumin counteracts the aluminium-induced ageing-related alterations in oxidative stress, Na+, K+ ATPase and protein kinase C in adult and old rat brain regions.

  Biogerontology 20090801

• Curcumin-induced DNA damage and inhibited DNA repair genes expressions in mouse-rat hybrid retina ganglion cells (N18).

  Neurochemical research 20090801

• Synthesis and biological evaluation of curcumin-like diarylpentanoid analogues for anti-inflammatory, antioxidant and anti-tyrosinase activities.

  European journal of medicinal chemistry 20090801

• New difluoro Knoevenagel condensates of curcumin, their Schiff bases and copper complexes as proteasome inhibitors and apoptosis inducers in cancer cells.

  Pharmaceutical research 20090801

• Inhibitory effect of curcumin on early liver regeneration following partial hepatectomy in rats.

  The Journal of surgical research 20090801

• Vascular cell adhesion molecule-1 expression in human intestinal microvascular endothelial cells is regulated by PI 3-kinase/Akt/MAPK/NF-kappaB: inhibitory role of curcumin.

  American journal of physiology. Gastrointestinal and liver physiology 20090801

• Nitric oxide-mediated toxicity in paraquat-exposed SH-SY5Y cells: a protective role of 7-nitroindazole.

  Neurotoxicity research 20090801

• Gene expression profiling of aging in multiple mouse strains: identification of aging biomarkers and impact of dietary antioxidants.

  Aging cell 20090801

• Curcumin suppresses expression of low-density lipoprotein (LDL) receptor, leading to the inhibition of LDL-induced activation of hepatic stellate cells.

  British journal of pharmacology 20090801

• Curcumin inhibits ACTH- and angiotensin II-stimulated cortisol secretion and Ca(v)3.2 current.

  Journal of natural products 20090801

• Neuroinflammation in Alzheimer's disease: different molecular targets and potential therapeutic agents including curcumin.

  Current opinion in pharmacology 20090801

• Curcumin inhibits proliferation of colorectal carcinoma by modulating Akt/mTOR signaling.

  Anticancer research 20090801

• Curcumin blocks prostaglandin E2 biosynthesis through direct inhibition of the microsomal prostaglandin E2 synthase-1.

  Molecular cancer therapeutics 20090801

• Curcumin adds spice to the debate: lipid metabolism in liver disease.

  British journal of pharmacology 20090801

• Gene expression profiling related to anti-inflammatory properties of curcumin in K562 leukemia cells.

  Annals of the New York Academy of Sciences 20090801

• Interleukin-1beta-induced extracellular matrix degradation and glycosaminoglycan release is inhibited by curcumin in an explant model of cartilage inflammation.

  Annals of the New York Academy of Sciences 20090801

• Effect of curcumin on nuclear factor kappaB signaling pathways in human chronic myelogenous K562 leukemia cells.

  Annals of the New York Academy of Sciences 20090801

• Regulatory effect of the AMPK-COX-2 signaling pathway in curcumin-induced apoptosis in HT-29 colon cancer cells.

  Annals of the New York Academy of Sciences 20090801

• Persistent short-term memory defects following sleep deprivation in a drosophila model of Parkinson disease.

  Sleep 20090801

• Select phytochemicals suppress human T-lymphocytes and mouse splenocytes suggesting their use in autoimmunity and transplantation.

  Nutrition research (New York, N.Y.) 20090801

• [Effects of curcumin on behavior and p-ERK, p-CREB, c-fos expression in dorsal root ganglion in chronic constrictive injury rats].

  Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20090801

• Curcumin upregulates transcription factor Nrf2, HO-1 expression and protects rat brains against focal ischemia.

  Brain research 20090728

• Preventive effect of curcumin and quercetin against nitric oxide mediated modification of goat lung cystatin.

  Journal of agricultural and food chemistry 20090722

• Dietary curcumin supplementation counteracts reduction in levels of molecules involved in energy homeostasis after brain trauma.

  Neuroscience 20090721

• Curcumin attenuates 6-hydroxydopamine-induced cytotoxicity by anti-oxidation and nuclear factor-kappa B modulation in MES23.5 cells.

  Biochemical pharmacology 20090715

• Novel 3alpha-methoxyserrat-14-en-21beta-ol (PJ-1) and 3beta-methoxyserrat-14-en-21beta-ol (PJ-2)-curcumin, kojic acid, quercetin, and baicalein conjugates as HIV agents.

  Bioorganic & medicinal chemistry 20090715

• Molecular modifications on carboxylic acid derivatives as potent histone deacetylase inhibitors: Activity and docking studies.

  Bioorganic & medicinal chemistry 20090715

• Chicken HS4 insulator significantly improves baculovirus-mediated foreign gene expression in insect cells by modifying the structure of neighbouring chromatin in virus minichromosome.

  Journal of biotechnology 20090715

• Beta-amyloid oligomers induce phosphorylation of tau and inactivation of insulin receptor substrate via c-Jun N-terminal kinase signaling: suppression by omega-3 fatty acids and curcumin.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20090715

• Demethoxycurcumin induces Bcl-2 mediated G2/M arrest and apoptosis in human glioma U87 cells.

  Biochemical and biophysical research communications 20090710

• Induction of heat shock response by curcumin in human leukemia cells.

  Cancer letters 20090708

• Curcumin improves spatial memory impairment induced by human immunodeficiency virus type 1 glycoprotein 120 V3 loop peptide in rats.

  Life sciences 20090703

• Release and activity of anti-TNFalpha therapeutics from injectable chitosan preparations for local drug delivery.

  Journal of biomedical materials research. Part B, Applied biomaterials 20090701

• Study on antifibrotic effects of curcumin in rat hepatic stellate cells.

  Phytotherapy research : PTR 20090701

• The up-regulation of monocyte chemoattractant protein-1 (MCP-1) in Ea.hy 926 endothelial cells under long-term low folate stress is mediated by the p38 MAPK pathway.

  Atherosclerosis 20090701

• Liver metastases after colonic carcinoma--palliative chemotherapy plus curcumin.

  International journal of colorectal disease 20090701

• Protective effect of curcumin in cisplatin-induced oxidative injury in rat testis: mitogen-activated protein kinase and nuclear factor-kappa B signaling pathways.

  Human reproduction (Oxford, England) 20090701

• Curcumin sensitizes lung cancer cells to cisplatin-induced apoptosis through superoxide anion-mediated Bcl-2 degradation.

  Cancer investigation 20090701

• Curcumin eliminates leptin's effects on hepatic stellate cell activation via interrupting leptin signaling.

  Endocrinology 20090701

• Liposome encapsulation of curcumin and resveratrol in combination reduces prostate cancer incidence in PTEN knockout mice.

  International journal of cancer 20090701

• Curcumin prevents oxidative renal damage induced by acetaminophen in rats.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090701

• The dietary polyphenols trans-resveratrol and curcumin selectively bind human CB1 cannabinoid receptors with nanomolar affinities and function as antagonists/inverse agonists.

  The Journal of pharmacology and experimental therapeutics 20090701

• Curcumin attenuates aluminium-induced functional neurotoxicity in rats.

  Pharmacology, biochemistry, and behavior 20090701

• Curcumin analogues exhibit enhanced growth suppressive activity in human pancreatic cancer cells.

  Anti-cancer drugs 20090701

• Polyethylene glycosylated curcumin conjugate inhibits pancreatic cancer cell growth through inactivation of Jab1.

  Molecular pharmacology 20090701

• Curcumin suppresses proliferation and invasion in human gastric cancer cells by downregulation of PAK1 activity and cyclin D1 expression.

  Cancer biology & therapy 20090701

• Spice active principles as the inhibitors of human platelet aggregation and thromboxane biosynthesis.

  Prostaglandins, leukotrienes, and essential fatty acids 20090701

• Curcumin induces apoptosis through FAS and FADD, in caspase-3-dependent and -independent pathways in the N18 mouse-rat hybrid retina ganglion cells.

  Oncology reports 20090701

• Curcumin's potential to modulate stem cell fate.

  Trends in pharmacological sciences 20090701

• Increasing aqueous solubility of curcumin for improving bioavailability.

  Trends in pharmacological sciences 20090701

• Curcumin in clinical practice: myth or reality?

  Trends in pharmacological sciences 20090701

• Spleen tyrosine kinase is overexpressed and represents a potential therapeutic target in chronic lymphocytic leukemia.

  Cancer research 20090701

• Dietary chemopreventive phytochemicals: too little or too much?

  Cancer prevention research (Philadelphia, Pa.) 20090701

• Curry spice curcumin and prostate cancer.

  Molecular nutrition & food research 20090701

• [Preventive effects of curcumin on acrylamide-induced DNA damage in HepG2 cells].

  Wei sheng yan jiu = Journal of hygiene research 20090701

• [The effect or rosiglitazone on signal pathways of transforming growth factor-beta1 in human lung fibroblast].

  Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20090701

• [Effects of dietary bioactive compounds on obesity induced inflammation].

  Arquivos brasileiros de endocrinologia e metabologia 20090701

• Nanoparticle encapsulation improves oral bioavailability of curcumin by at least 9-fold when compared to curcumin administered with piperine as absorption enhancer.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20090628

• Development of curcuminoids loaded poly(butyl) cyanoacrylate nanoparticles: Physicochemical characterization and stability study.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20090628

• Comment on Curcumin attenuates acrylamide-induced cytotoxicity and genotoxicity in HepG2 cells by ROS scavenging.

  Journal of agricultural and food chemistry 20090624

• Curcumin inhibits amygdaloid kindled seizures in rats.

  Chinese medical journal 20090620

• Decreased activity of neutrophils in the presence of diferuloylmethane (curcumin) involves protein kinase C inhibition.

  European journal of pharmacology 20090610

• Curcumin mediates time and concentration dependent regulation of redox homeostasis leading to cytotoxicity in macrophage cells.

  European journal of pharmacology 20090602

• Encapsulation and sustained release of curcumin using superparamagnetic silica reservoirs.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20090602

• Inhibition of glycogen synthase kinase by curcumin: Investigation by simulated molecular docking and subsequent in vitro/in vivo evaluation.

  Journal of enzyme inhibition and medicinal chemistry 20090601

• Protective effects of curcumin against gamma radiation-induced ileal mucosal damage.

  Archives of toxicology 20090601

• Serenoa repens associated with Urtica dioica (ProstaMEV) and curcumin and quercitin (FlogMEV) extracts are able to improve the efficacy of prulifloxacin in bacterial prostatitis patients: results from a prospective randomised study.

  International journal of antimicrobial agents 20090601

• Can curry protect the brain from bilirubin toxicity?

  Medical hypotheses 20090601

• Cytoskeleton disorganization during apoptosis induced by curcumin in A549 lung adenocarcinoma cells.

  Planta medica 20090601

• Inhibition of vascular smooth-muscle cell proliferation and arterial restenosis by HO-3867, a novel synthetic curcuminoid, through up-regulation of PTEN expression.

  The Journal of pharmacology and experimental therapeutics 20090601

• A cell-based system for screening hair growth-promoting agents.

  Archives of dermatological research 20090601

• Prophylactic role of curcumin in dextran sulfate sodium (DSS)-induced ulcerative colitis murine model.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090601

• Modulation of ovarian structure and abdominal obesity in curcumin- and flutamide-treated aging FSH-R haploinsufficient mice.

  Reproductive sciences (Thousand Oaks, Calif.) 20090601

• Curcumin prevents shock-wave lithotripsy-induced renal injury through inhibition of nuclear factor kappa-B and inducible nitric oxide synthase activity in rats.

  Urological research 20090601

• Lung tumor promotion by curcumin.

  Carcinogenesis 20090601

• Histone acetyltransferase inhibitors and preclinical studies.

  Expert opinion on therapeutic patents 20090601

• Determination of minimum effective dose and optimal dosing schedule for liposomal curcumin in a xenograft human pancreatic cancer model.

  Anticancer research 20090601

• [Inhibitory effect of curcumin on MMP-2 and MMP-9 expression induced by polyethylene wear particles and its mechanism].

  Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery 20090601

• Anti-inflammatory properties of curcumin, a major constituent of Curcuma longa: a review of preclinical and clinical research.

  Alternative medicine review : a journal of clinical therapeutic 20090601

• Investigation of curcumin-cyclodextrin inclusion complexation in aqueous solutions containing various alcoholic co-solvents and alginates using an UV-VIS titration method. Studies of curcumin and curcuminoides, XXXV.

  Die Pharmazie 20090601

• Determination of in vitro antioxidative and antimicrobial properties and total phenolic contents of Ziziphora clinopodioides, Cyclotrichium niveum, and Mentha longifolia ssp. typhoides var. typhoides.

  Journal of medicinal food 20090601

• [Effects of curcumin on the expression of nuclear factor-kappaB and intercellular adhesion molecular 1 in rats with cerebral ischemia-reperfusion injury].

  Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20090601

• Effect of exclusion diet with nutraceutical therapy in juvenile Crohn's disease.

  Journal of the American College of Nutrition 20090601

• Effective stabilization of curcumin by association to plasma proteins: human serum albumin and fibrinogen.

  Langmuir : the ACS journal of surfaces and colloids 20090519

• Vasoactive intestinal peptide behaves as a pro-metastatic factor in human prostate cancer cells.

  The Prostate 20090515

• Binding and stabilization of transthyretin by curcumin.

  Archives of biochemistry and biophysics 20090515

• Curcuminoids suppress the growth of pharynx and nasopharyngeal carcinoma cells through induced apoptosis.

  Journal of agricultural and food chemistry 20090513

• Activation of ATM/Chk1 by curcumin causes cell cycle arrest and apoptosis in human pancreatic cancer cells.

  British journal of cancer 20090505

• Curcumin, a nutritional supplement with antineoplastic activity, enhances leiomyoma cell apoptosis and decreases fibronectin expression.

  Fertility and sterility 20090501

• Induction of antioxidant enzymes by curcumin and its analogues in human islets: implications in transplantation.

  Pancreas 20090501

• Interaction of curcumin and diacetylcurcumin with the lipocalin member beta-lactoglobulin.

  The protein journal 20090501

• Molecular mechanism of curcumin induced cytotoxicity in human cervical carcinoma cells.

  Molecular and cellular biochemistry 20090501

• Curcumin ameliorates renal failure in 5/6 nephrectomized rats: role of inflammation.

  American journal of physiology. Renal physiology 20090501

• Curcumin inhibits adipogenesis in 3T3-L1 adipocytes and angiogenesis and obesity in C57/BL mice.

  The Journal of nutrition 20090501

• Interactions of curcumin with the PfATP6 model and the implications for its antimalarial mechanism.

  Bioorganic & medicinal chemistry letters 20090501

• Curcumin blocks CCL2-induced adhesion, motility and invasion, in part, through down-regulation of CCL2 expression and proteolytic activity.

  International journal of oncology 20090501

• Uroprotective effects of curcumin in cyclophosphamide-induced haemorrhagic cystitis paradigm.

  Basic & clinical pharmacology & toxicology 20090501

• Isolation of dihydrocurcuminoids from cell clumps and their distribution in various parts of turmeric (Curcuma longa).

  Bioscience, biotechnology, and biochemistry 20090501

• Effects of benzylidenecyclopentanone analogues of curcumin on histamine release from mast cells.

  Biological & pharmaceutical bulletin 20090501

• [Effects of curcumin on TNF-alpha and TGF-beta1 in serum and lung tissue of SiO2-induced fibrosis in mice].

  Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20090501

• Newly synthesized curcumin analog has improved potential to prevent colorectal carcinogenesis in vivo.

  Cancer science 20090501

• Analysis of binding interaction of curcumin and diacetylcurcumin with human and bovine serum albumin using fluorescence and circular dichroism spectroscopy.

  The protein journal 20090501

• Amelioration of experimental autoimmune encephalomyelitis by curcumin treatment through inhibition of IL-17 production.

  International immunopharmacology 20090501

• [Research on the evaluation methods for antioxidant capacity of several bioactive substances in vitro].

  Wei sheng yan jiu = Journal of hygiene research 20090501

• [Regulation of protein kinases on signal pathway in breast cancer cell MCF-7 by curcumin].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20090501

• [Study on effects of curcumin on expressions of PDGF-BB, PDGFRbeta and ERK1 of HSC].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20090501

• [Analysis of minor curcuminoids in Curcuma longa L. by high performance liquid chromatography-tandem mass spectrometry].

  Se pu = Chinese journal of chromatography 20090501

• Apoptotic effects of curcumin on human osteosarcoma U2OS cells.

  Orthopaedic surgery 20090501

• Antidepressant-like effects of curcumin on serotonergic receptor-coupled AC-cAMP pathway in chronic unpredictable mild stress of rats.

  Progress in neuro-psychopharmacology & biological psychiatry 20090430

• Evaluation of the cytotoxicity and genotoxicity of curcumin in PC12 cells.

  Mutation research 20090430

• Free energies of molecular bound states in lipid bilayers: lethal concentrations of antimicrobial peptides.

  Biophysical journal 20090422

• Enhancement of oral absorption of curcumin by self-microemulsifying drug delivery systems.

  International journal of pharmaceutics 20090417

• Excited-state intramolecular hydrogen atom transfer and solvation dynamics of the medicinal pigment curcumin.

  The journal of physical chemistry. B 20090416

• Synthesis, cytotoxic and combined cDDP activity of new stable curcumin derivatives.

  Bioorganic & medicinal chemistry 20090415

• Curcumin attenuates ethanol-induced toxicity in HT22 hippocampal cells by activating mitogen-activated protein kinase phosphatase-1.

  Neuroscience letters 20090410

• The protective role of curcumin in cardiovascular diseases.

  International journal of cardiology 20090403

• Curcumin-induced fibroblast apoptosis and in vitro wound contraction are regulated by antioxidants and heme oxygenase: implications for scar formation.

  Journal of cellular and molecular medicine 20090401

• Areca nut extracts increased expression of inflammatory cytokines, tumor necrosis factor-alpha, interleukin-1beta, interleukin-6 and interleukin-8, in peripheral blood mononuclear cells.

  Journal of periodontal research 20090401

• Evaluation of antihyperalgesic effect of curcumin on formalin-induced orofacial pain in rat.

  Phytotherapy research : PTR 20090401

• A novel curcumin assay with the metal ion Cu (II) as a simple probe by resonance light scattering technique.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20090401

• In vitro schistosomicidal activity of curcumin against Schistosoma mansoni adult worms.

  Parasitology research 20090401

• Curcumin-induced degradation of PKC delta is associated with enhanced dentate NCAM PSA expression and spatial learning in adult and aged Wistar rats.

  Biochemical pharmacology 20090401

• Curcumin attenuates oxidative damage in animals treated with a renal carcinogen, ferric nitrilotriacetate (Fe-NTA): implications for cancer prevention.

  Molecular and cellular biochemistry 20090401

• Curcumin attenuates elastase- and cigarette smoke-induced pulmonary emphysema in mice.

  American journal of physiology. Lung cellular and molecular physiology 20090401

• Comparative antiulcer effect of bisdemethoxycurcumin and curcumin in a gastric ulcer model system.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20090401

• Cell-cycle inhibition and apoptosis induced by curcumin and cisplatin or oxaliplatin in human ovarian carcinoma cells.

  Cell proliferation 20090401

• Structure-activity relationship studies of curcumin analogues.

  Bioorganic & medicinal chemistry letters 20090401

• Determining the effects of lipophilic drugs on membrane structure by solid-state NMR spectroscopy: the case of the antioxidant curcumin.

  Journal of the American Chemical Society 20090401

• Cigarette smoke extract induces cytosolic phospholipase A2 expression via NADPH oxidase, MAPKs, AP-1, and NF-kappaB in human tracheal smooth muscle cells.

  Free radical biology & medicine 20090401

• Curcumin inhibits proliferation and migration by increasing the Bax to Bcl-2 ratio and decreasing NF-kappaBp65 expression in breast cancer MDA-MB-231 cells.

  International journal of molecular medicine 20090401

• Inhibition of human glutathione S-transferases by curcumin and analogues.

  Xenobiotica; the fate of foreign compounds in biological systems 20090401

• Curcumin binding to DNA and RNA.

  DNA and cell biology 20090401

• Curcumin circumvents chemoresistance in vitro and potentiates the effect of thalidomide and bortezomib against human multiple myeloma in nude mice model.

  Molecular cancer therapeutics 20090401

• Rapamycin and curcumin induce apoptosis in primary resting B chronic lymphocytic leukemia cells.

  Leukemia & lymphoma 20090401

• Inhibition studies of bovine xanthine oxidase by luteolin, silibinin, quercetin, and curcumin.

  Journal of natural products 20090401

• The role of Curcuma longa against doxorubicin (adriamycin)-induced toxicity in rats.

  Journal of medicinal food 20090401

• Vanilloid-mediated apoptosis in prostate cancer cells through a TRPV-1 dependent and a TRPV-1-independent mechanism.

  Acta bio-medica : Atenei Parmensis 20090401

• Characterization and cytotoxicity of self-organized assemblies of curcumin and amphiphatic poly(ethylene glycol).

  Journal of biomedical nanotechnology 20090401

• Curcumin induces apoptosis and inhibits growth of human Burkitt's lymphoma in xenograft mouse model.

  Molecules and cells 20090331

• Curcumin suppresses PPARdelta expression and related genes in HT-29 cells.

  World journal of gastroenterology 20090321

• Curcumin in combination with visible light inhibits tumor growth in a xenograft tumor model.

  International journal of cancer 20090315

• Exploration and synthesis of curcumin analogues with improved structural stability both in vitro and in vivo as cytotoxic agents.

  Bioorganic & medicinal chemistry 20090315

• Antigen-specific suppression of inflammatory arthritis using liposomes.

  Journal of immunology (Baltimore, Md. : 1950) 20090315

• Alcohol metabolites and lipopolysaccharide: roles in the development and/or progression of alcoholic liver disease.

  World journal of gastroenterology 20090314

• Supplementation of curcumin and vitamin E enhances oxidative stress, but restores hepatic histoarchitecture in hypothyroid rats.

  Life sciences 20090313

• Neuroprotective and antiinflammatory properties of a novel demethylated curcuminoid.

  Antioxidants & redox signaling 20090301

• Anti-depressant like effect of curcumin and its combination with piperine in unpredictable chronic stress-induced behavioral, biochemical and neurochemical changes.

  Pharmacology, biochemistry, and behavior 20090301

• The effects of hydroxycinnamic acid derivatives on adiponectin secretion.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20090301

• Curcumin protects retinal cells from light-and oxidant stress-induced cell death.

  Free radical biology & medicine 20090301

• Syntheses, characterization and biological activities of rare earth metal complexes with curcumin and 1,10-phenanthroline-5,6-dione.

  Journal of inorganic biochemistry 20090301

• Currying the heart: curcumin and cardioprotection.

  Journal of cardiovascular pharmacology and therapeutics 20090301

• Curcumin protects PC12 cells from corticosterone-induced cytotoxicity: possible involvement of the ERK1/2 pathway.

  Basic & clinical pharmacology & toxicology 20090301

• Synthesis of sulfonyl curcumin mimics exerting a vasodilatation effect on the basilar artery of rabbits.

  Bioorganic & medicinal chemistry letters 20090301

• Curcumin, quercetin, and tBHQ modulate glutathione levels in astrocytes and neurons: importance of the glutamate cysteine ligase modifier subunit.

  Journal of neurochemistry 20090301

• Wilms' tumour gene 1 (WT1) as a target in curcumin treatment of pancreatic cancer cells.

  European journal of cancer (Oxford, England : 1990) 20090301

• Bcl-XL protein is markedly decreased in UVB-irradiated basal cell carcinoma cell lines through proteasome-mediated degradation.

  Oncology reports 20090301

• Novel formulation of solid lipid microparticles of curcumin for anti-angiogenic and anti-inflammatory activity for optimization of therapy of inflammatory bowel disease.

  The Journal of pharmacy and pharmacology 20090301

• Pharmacokinetics prediction and drugability assessment of diphenylheptanoids from turmeric (Curcuma longa L).

  Medicinal chemistry (Shariqah (United Arab Emirates)) 20090301

• A simple HPLC-fluorescence method for quantitation of curcuminoids and its application to turmeric products.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20090301

• Drug targeting to the hair follicles: a cyclodextrin-based drug delivery.

  AAPS PharmSciTech 20090301

• Curcumin potentiates the anti-inflammatory activity of cyclooxygenase inhibitors in the cotton pellet granuloma pouch model.

  Methods and findings in experimental and clinical pharmacology 20090301

• [Study of the property of lipids reducing of curcumin on hyperlipidemia mice after fermented by Monascus purureus].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20090301

• [Preparation and characterization of curcumin loaded gelatin microspheres for lung targeting].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20090301

• [The effect of curcumin on DNA content, mitochondrial transmembrane potential and calcium of rabbit cultured retinal pigment epithelial cells].

  [Zhonghua yan ke za zhi] Chinese journal of ophthalmology 20090301

• [Curcumin attenuates left ventricular dysfunction and remodeling in rabbits with chronic heart failure.].

  Zhonghua xin xue guan bing za zhi 20090301

• Study of curcumin and genistein interactions with human serum albumin.

  Journal of pharmaceutical and biomedical analysis 20090220

• Turmeric and green tea: a recipe for the treatment of B-chronic lymphocytic leukemia.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20090215

• Curcumin inhibits prosurvival pathways in chronic lymphocytic leukemia B cells and may overcome their stromal protection in combination with EGCG.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20090215

• Rapid analysis of curcumin and curcumin metabolites in rat biomatrices using a novel ultraperformance liquid chromatography (UPLC) method.

  Journal of agricultural and food chemistry 20090211

• Grape seed polyphenols and curcumin reduce genomic instability events in a transgenic mouse model for Alzheimer's disease.

  Mutation research 20090210

• Effects and underlying mechanisms of curcumin on the proliferation of vascular smooth muscle cells induced by Chol:MbetaCD.

  Biochemical and biophysical research communications 20090206

• Curcumin enhances non-inflammatory phagocytic activity of RAW264.7 cells.

  Biochemical and biophysical research communications 20090206

• Interaction of tea catechin (-)-epigallocatechin gallate with lipid bilayers.

  Biophysical journal 20090204

• Effect of curcumin on aflatoxin-induced biochemical changes in testis of mice.

  Fertility and sterility 20090201

• Synthesis, crystal structure and anti-inflammatory properties of curcumin analogues.

  European journal of medicinal chemistry 20090201

• Curcumin, demethoxycurcumin and bisdemethoxycurcumin differentially inhibit cancer cell invasion through the down-regulation of MMPs and uPA.

  The Journal of nutritional biochemistry 20090201

• Curcumin diminishes human osteoclastogenesis by inhibition of the signalosome-associated I kappaB kinase.

  Journal of cancer research and clinical oncology 20090201

• Design and evaluation of transdermal drug delivery system for curcumin as an anti-inflammatory drug.

  Drug development and industrial pharmacy 20090201

• Effects of curcumin or dexamethasone on lung ischaemia-reperfusion injury in rats.

  The European respiratory journal 20090201

• Molecular interactions of isoxazolcurcumin with human serum albumin: spectroscopic and molecular modeling studies.

  Biopolymers 20090201

• Curcumin inhibits the activity of ABCG2/BCRP1, a multidrug resistance-linked ABC drug transporter in mice.

  Pharmaceutical research 20090201

• Inhibitory effect of curcuminoids on acetylcholinesterase activity and attenuation of scopolamine-induced amnesia may explain medicinal use of turmeric in Alzheimer's disease.

  Pharmacology, biochemistry, and behavior 20090201

• Curcumin supplementation lowers TNF-alpha, IL-6, IL-8, and MCP-1 secretion in high glucose-treated cultured monocytes and blood levels of TNF-alpha, IL-6, MCP-1, glucose, and glycosylated hemoglobin in diabetic rats.

  Antioxidants & redox signaling 20090201

• Curcumin attenuates inflammation through inhibition of TLR-4 receptor in experimental colitis.

  Molecular and cellular biochemistry 20090201

• Curcumin and muscle wasting: a new role for an old drug?

  Nutrition (Burbank, Los Angeles County, Calif.) 20090201

• Curcumin as a promising antifungal of clinical interest.

  The Journal of antimicrobial chemotherapy 20090201

• Synergistic induction of heme oxygenase-1 by the components of the antioxidant supplement Protandim.

  Free radical biology & medicine 20090201

• Effect of curcumin on acidic pH-induced expression of IL-6 and IL-8 in human esophageal epithelial cells (HET-1A): role of PKC, MAPKs, and NF-kappaB.

  American journal of physiology. Gastrointestinal and liver physiology 20090201

• Phytochemicals as potential chemopreventive and chemotherapeutic agents in hepatocarcinogenesis.

  European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 20090201

• Mechanisms of cytotoxicity of 2- or 2,6-di-tert-butylphenols and 2-methoxyphenols in terms of inhibition rate constant and a theoretical parameter.

  Chemosphere 20090201

• Age-related differential responses to curcumin-induced apoptosis during the initiation of colon cancer in rats.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090201

• Curcumin protects against electrobehavioral progression of seizures in the iron-induced experimental model of epileptogenesis.

  Epilepsy & behavior : E&B 20090201

• Pharmacological basis for the role of curcumin in chronic diseases: an age-old spice with modern targets.

  Trends in pharmacological sciences 20090201

• Curcumin is a potent DNA hypomethylation agent.

  Bioorganic & medicinal chemistry letters 20090201

• Bisubstrate Inhibitors of the MYST HATs Esa1 and Tip60.

  Bioorganic & medicinal chemistry 20090201

• Synthesis and biological evaluation of curcuminoid pyrazoles as new therapeutic agents in inflammatory bowel disease: effect on matrix metalloproteinases.

  Bioorganic & medicinal chemistry 20090201

• Interleukin-1beta-induced disruption of barrier function in cultured human corneal epithelial cells.

  Investigative ophthalmology & visual science 20090201

• Curcumin disrupts the Mammalian target of rapamycin-raptor complex.

  Cancer research 20090201

• Increasing the solubility of the nutraceutical curcumin by heat and inhibition of oxidative modification.

  Molecular nutrition & food research 20090201

• Suppression of interleukin 6 and 8 production in head and neck cancer cells with curcumin via inhibition of Ikappa beta kinase.

  Archives of otolaryngology--head & neck surgery 20090201

• Curcumin-induced histone acetylation in malignant hematologic cells.

  Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20090201

• Curcumin induces apoptosis through the mitochondria-mediated apoptotic pathway in HT-29 cells.

  Journal of Zhejiang University. Science. B 20090201

• Curcumin as a possible lead compound against hormone-independent, multidrug-resistant breast cancer.

  Annals of the New York Academy of Sciences 20090201

• Chemopreventive efficacy of curcumin and piperine during 7,12-dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis.

  Singapore medical journal 20090201

• Cardioprotective effect of tetrahydrocurcumin and rutin on lipid peroxides and antioxidants in experimentally induced myocardial infarction in rats.

  Die Pharmazie 20090201

• Curcumin arrests endometriosis by downregulation of matrix metalloproteinase-9 activity.

  Indian journal of biochemistry & biophysics 20090201

• [Effects of curcumin on malondialdehyde and c-fos protein in hypoxia ischemia brain tissue in rats].

  Fa yi xue za zhi 20090201

• Curcumin, a potential inhibitor of up-regulation of TNF-alpha and IL-6 induced by palmitate in 3T3-L1 adipocytes through NF-kappaB and JNK pathway.

  Biomedical and environmental sciences : BES 20090201

• [Preparation and drug releasing property of curcumin nanoparticles].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20090201

• Synthesis, oxidant properties, and antitumoral effects of a heteroleptic palladium(II) complex of curcumin on human prostate cancer cells.

  Journal of medicinal chemistry 20090122

• An in vitro study of liposomal curcumin: stability, toxicity and biological activity in human lymphocytes and Epstein-Barr virus-transformed human B-cells.

  International journal of pharmaceutics 20090121

• Cancer preventive agents. Part 8: Chemopreventive effects of stevioside and related compounds.

  Bioorganic & medicinal chemistry 20090115

• Heat-solubilized curcumin should be considered in clinical trials for increasing bioavailability.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20090115

• Curcumin exerts antidifferentiation effect through AMPKalpha-PPAR-gamma in 3T3-L1 adipocytes and antiproliferatory effect through AMPKalpha-COX-2 in cancer cells.

  Journal of agricultural and food chemistry 20090114

• Curcumin, a cancer chemopreventive and chemotherapeutic agent, is a biologically active iron chelator.

  Blood 20090108

• Curcumin blocks chronic morphine analgesic tolerance and brain-derived neurotrophic factor upregulation.

  Neuroreport 20090107

• Curcumin attenuates ischemia-reperfusion injury in rat testis.

  Fertility and sterility 20090101

• Curcumin reduces the toxic effects of iron loading in rat liver epithelial cells.

  Liver international : official journal of the International Association for the Study of the Liver 20090101

• Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic diseases.

  The international journal of biochemistry & cell biology 20090101

• Application of Scion image software to the simultaneous determination of curcuminoids in turmeric (Curcuma longa).

  Phytochemical analysis : PCA 20090101

• Identification of Curcuma plants and curcumin content level by DNA polymorphisms in the trnS-trnfM intergenic spacer in chloroplast DNA.

  Journal of natural medicines 20090101

• Effects of curcumin on ethanol-induced hepatocyte necrosis and apoptosis: implication of lipid peroxidation and cytochrome c.

  Naunyn-Schmiedeberg's archives of pharmacology 20090101

• Curcumin attenuates vascular inflammation and cerebral vasospasm after subarachnoid hemorrhage in mice.

  Antioxidants & redox signaling 20090101

• The effects of dietary curcumin and rutin on colonic inflammation and gene expression in multidrug resistance gene-deficient (mdr1a-/-) mice, a model of inflammatory bowel diseases.

  The British journal of nutrition 20090101

• Comment on: comparison between chondroprotective effects of glucosamine, curcumin and diacerein in IL-1beta-stimulated C-28/I2 chondrocytes.

  Osteoarthritis and cartilage 20090101

• Formulation and evaluation of curcumin gel for topical application.

  Pharmaceutical development and technology 20090101

• TLR-4 agonistic lipopolysaccharide upregulates interleukin-8 at the transcriptional and post-translational level in vascular smooth muscle cells.

  Vascular pharmacology 20090101

• Curcumin reverses attenuated carbachol-induced contraction of the colon in a rat model of colitis.

  Scandinavian journal of gastroenterology 20090101

• Synergistic effect of combination of phenethyl isothiocyanate and sulforaphane or curcumin and sulforaphane in the inhibition of inflammation.

  Pharmaceutical research 20090101

• Preventive effects of curcumin on different aspiration material-induced lung injury in rats.

  Pediatric surgery international 20090101

• Synthesis and evaluation of electron-rich curcumin analogues.

  Bioorganic & medicinal chemistry 20090101

• Ameliorating effect of curcumin on sodium arsenite-induced oxidative damage and lipid peroxidation in different rat organs.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090101

• Developing curcumin into a viable therapeutic for lymphoma.

  Expert opinion on investigational drugs 20090101

• Proteomics-based approach to elucidate the mechanism of antitumor effect of curcumin in cervical cancer.

  Prostaglandins, leukotrienes, and essential fatty acids 20090101

• Ultraviolet radiation-induced transcription is associated with gene-specific histone acetylation.

  Photochemistry and photobiology 20090101

• Selective killing of leukemia and lymphoma cells ectopically expressing hCGbeta by a conjugate of curcumin with an antibody against hCGbeta subunit.

  Oncology 20090101

• Curcumin, a polyphenolic antioxidant, attenuates chronic fatigue syndrome in murine water immersion stress model.

  Immunobiology 20090101

• Dimethoxycurcumin, a Synthetic Curcumin Analogue, Induces Heme Oxygenase-1 Expression through Nrf2 Activation in RAW264.7 Macrophages.

  Journal of clinical biochemistry and nutrition 20090101

• Anti-malarial activities of Andrographis paniculata and Hedyotis corymbosa extracts and their combination with curcumin.

  Malaria journal 20090101

• Immunomodulatory effects of curcumin treatment on murine schistosomiasis mansoni.

  Immunobiology 20090101

• Vitagenes, dietary antioxidants and neuroprotection in neurodegenerative diseases.

  Frontiers in bioscience (Landmark edition) 20090101

• Coadministration of Paclitaxel and curcumin in nanoemulsion formulations to overcome multidrug resistance in tumor cells.

  Molecular pharmaceutics 20090101

• Curcumin synergizes the growth inhibitory properties of Indian toad (Bufo melanostictus Schneider) skin-derived factor (BM-ANF1) in HCT-116 colon cancer cells.

  Anticancer research 20090101

• New structural analogues of curcumin exhibit potent growth suppressive activity in human colorectal carcinoma cells.

  BMC cancer 20090101

• Uses of turmeric in dentistry: an update.

  Indian journal of dental research : official publication of Indian Society for Dental Research 20090101

• Chemoprotective mechanism of the natural compounds, epigallocatechin-3-O-gallate, quercetin and curcumin against cancer and cardiovascular diseases.

  Current medicinal chemistry 20090101

• Chemoprevention with phytochemicals targeting inducible nitric oxide synthase.

  Forum of nutrition 20090101

• Design and optimization of ultrasound assisted extraction of curcumin as an effective alternative for conventional solid liquid extraction of natural products.

  Natural product communications 20090101

• Effects of curcuminoid supplement on cardiac autonomic status in high-fat-induced obese rats.

  Nutrition (Burbank, Los Angeles County, Calif.) 20090101

• A simple isocratic HPLC method for the simultaneous determination of curcuminoids in commercial turmeric extracts.

  Phytochemical analysis : PCA 20090101

• 1alpha,25-dihydroxyvitamin D3 interacts with curcuminoids to stimulate amyloid-beta clearance by macrophages of Alzheimer's disease patients.

  Journal of Alzheimer's disease : JAD 20090101

• [Effects of curcumin on apoptosis of pulmonary fibroblasts from rats].

  Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20090101

• Simple HPLC method for resolution of curcuminoids with antioxidant potential.

  Journal of food science 20090101

• Fabrication and characterization of silk fibroin-derived curcumin nanoparticles for cancer therapy.

  International journal of nanomedicine 20090101

• Editorial: The impact of microbiota and cytokines on inflammatory bowel disease.

  Current pharmaceutical design 20090101

• Curcumin has bright prospects for the treatment of inflammatory bowel disease.

  Current pharmaceutical design 20090101

• Direct analysis of curcumin in turmeric by DART-MS.

  Phytochemical analysis : PCA 20090101

• Anti-neoplastic activity of curcumin in PCa.

  International braz j urol : official journal of the Brazilian Society of Urology 20090101

• An evaluation of the anti-neoplastic activity of curcumin in prostate cancer cell lines.

  International braz j urol : official journal of the Brazilian Society of Urology 20090101

• Curcuminoids: Spicing up sympathovagal tone.

  Nutrition (Burbank, Los Angeles County, Calif.) 20090101

• [Reversal of multidrug resistance of the drug resistant human multiple myeloma cell line MOLP-2/R by curcumin and its relation with FA/BRCA pathway].

  Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20090101

• Immune modulation by lactoferrin and curcumin in children with recurrent respiratory infections.

  Journal of biological regulators and homeostatic agents 20090101

• Curcumin decreased oxidative stress, inhibited NF-kappaB activation, and improved liver pathology in ethanol-induced liver injury in rats.

  Journal of biomedicine & biotechnology 20090101

• Curcumin suppresses the paclitaxel-induced nuclear factor-kappaB in breast cancer cells and potentiates the growth inhibitory effect of paclitaxel in a breast cancer nude mice model.

  The breast journal 20090101

• Polymer-drug interactions in tyrosine-derived triblock copolymer nanospheres: a computational modeling approach.

  Molecular pharmaceutics 20090101

• A combination of curcumin and ginger extract improves abrasion wound healing in corticosteroid-impaired hairless rat skin.

  Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 20090101

• Involvement of VDAC, Bax and ceramides in the efflux of AIF from mitochondria during curcumin-induced apoptosis.

  PloS one 20090101

• Plant-derived health: the effects of turmeric and curcuminoids.

  Nutricion hospitalaria 20090101

• Assessing the neuroprotective effect of antioxidative food factors by application of lipid-derived dopamine modification adducts.

  Methods in molecular biology (Clifton, N.J.) 20090101

• Protective effect of curcumin against kainic acid induced seizures and oxidative stress in rats.

  Indian journal of physiology and pharmacology 20090101

• Dietary curcumin enhances benzo(a)pyrene-induced apoptosis resulting in a decrease in BPDE-DNA adducts in mice.

  Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20090101

• Curcumin synergizes with resveratrol to inhibit colon cancer.

  Nutrition and cancer 20090101

• Effects of curcumin in an orthotopic murine bladder tumor model.

  International braz j urol : official journal of the Brazilian Society of Urology 20090101

• Potentials of curcumin as an antidepressant.

  TheScientificWorldJournal 20090101

• Synergistic chondroprotective effects of curcumin and resveratrol in human articular chondrocytes: inhibition of IL-1beta-induced NF-kappaB-mediated inflammation and apoptosis.

  Arthritis research & therapy 20090101

• Chitosan-alginate sponge: preparation and application in curcumin delivery for dermal wound healing in rat.

  Journal of biomedicine & biotechnology 20090101

• An investigation of the molecular interactions of diacetylcurcumin with ribonuclease A.

  Protein and peptide letters 20090101

• Overexpression of the ATP binding cassette gene ABCA1 determines resistance to Curcumin in M14 melanoma cells.

  Molecular cancer 20090101

• Monoketone analogs of curcumin, a new class of Fanconi anemia pathway inhibitors.

  Molecular cancer 20090101

• Synergistic role of curcumin with current therapeutics in colorectal cancer: minireview.

  Nutrition and cancer 20090101

• Curcumin: from food spice to cancer prevention.

  Asian Pacific journal of cancer prevention : APJCP 20090101

• Curcuminoid-phospholipid complex induces apoptosis in mammary epithelial cells by STAT-3 signaling.

  Experimental & molecular medicine 20081231

• Natural derivatives of curcumin attenuate the Wnt/beta-catenin pathway through down-regulation of the transcriptional coactivator p300.

  Biochemical and biophysical research communications 20081226

• Curcumin attenuates acrylamide-induced cytotoxicity and genotoxicity in HepG2 cells by ROS scavenging.

  Journal of agricultural and food chemistry 20081224

• Translational bypass of nonsense mutations in zebrafish rep1, pax2.1 and lamb1 highlights a viable therapeutic option for untreatable genetic eye disease.

  Human molecular genetics 20081215

• DNA damage and endoplasmic reticulum stress mediated curcumin-induced cell cycle arrest and apoptosis in human lung carcinoma A-549 cells through the activation caspases cascade- and mitochondrial-dependent pathway.

  Cancer letters 20081208

• Comparison of inhibitory potency of three different curcuminoid pigments on nitric oxide and tumor necrosis factor production of rat primary microglia induced by lipopolysaccharide.

  Neuroscience letters 20081205

• Comparative efficacy of piperine, curcumin and picroliv against Cd immunotoxicity in mice.

  Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20081201

• Curcumin has anticonvulsant activity on increasing current electroshock seizures in mice.

  Phytotherapy research : PTR 20081201

• The ovariectomized, mature rat model of postmenopausal osteoporosis: an assessment of the bone sparing effects of curcumin.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20081201

• Differential effects of curcumin on cryopreserved versus fresh primary human hepatocytes.

  Phytotherapy research : PTR 20081201

• Modulation of anti-apoptotic and survival pathways by curcumin as a strategy to induce apoptosis in cancer cells.

  Biochemical pharmacology 20081201

• Antidepressant activity of curcumin: involvement of serotonin and dopamine system.

  Psychopharmacology 20081201

• Biological activities of curcumin and its analogues (Congeners) made by man and Mother Nature.

  Biochemical pharmacology 20081201

• Heme oxygenase-1 inhibits the proliferation of pancreatic stellate cells by repression of the extracellular signal-regulated kinase1/2 pathway.

  The Journal of pharmacology and experimental therapeutics 20081201

• Long-term use of an antiinflammatory, curcumin, suppressed type 1 immunity and exacerbated visceral leishmaniasis in a chronic experimental model.

  Laboratory investigation; a journal of technical methods and pathology 20081201

• Osteopontin prevents curcumin-induced apoptosis and promotes survival through Akt activation via alpha v beta 3 integrins in human gastric cancer cells.

  Experimental biology and medicine (Maywood, N.J.) 20081201

• Heme induces endothelial tissue factor expression: potential role in hemostatic activation in patients with hemolytic anemia.

  Journal of thrombosis and haemostasis : JTH 20081201

• Demethoxycurcumin and its semisynthetic analogues as antitubercular agents.

  Planta medica 20081201

• Curcumin attenuates cytochrome P450 induction in response to 2,3,7,8-tetrachlorodibenzo-p-dioxin by ROS-dependently degrading AhR and ARNT.

  Cancer science 20081201

• AMPK mediates curcumin-induced cell death in CaOV3 ovarian cancer cells.

  Oncology reports 20081201

• Drug development for liver diseases: focus on picroliv, ellagic acid and curcumin.

  Fundamental & clinical pharmacology 20081201

• Curcumin inhibits proliferation and induces apoptosis of leukemic cells expressing wild-type or T315I-BCR-ABL and prolongs survival of mice with acute lymphoblastic leukemia.

  Hematology (Amsterdam, Netherlands) 20081201

• [The effects of curcumin on the expression of acetyl-CoA carboxylase of HL-7702 cells].

  Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20081201

• [Changes of nuclear matrix proteins during apoptosis of human osteosarcoma MG-63 cells induced by curcumin].

  Fen zi xi bao sheng wu xue bao = Journal of molecular cell biology 20081201

• Combinatorial biosynthesis of non-bacterial and unnatural flavonoids, stilbenoids and curcuminoids by microorganisms.

  The Journal of antibiotics 20081201

• Cytotoxic effects of catechol to neuroblastoma N2a cells.

  General physiology and biophysics 20081201

• Curcumin in combination with bortezomib synergistically induced apoptosis in human multiple myeloma U266 cells.

  Molecular oncology 20081201

• Curcumin inhibits osteoclastogenesis by decreasing receptor activator of nuclear factor-kappaB ligand (RANKL) in bone marrow stromal cells.

  Molecules and cells 20081130

• Protective effects of vitamin E and curcumin on L-thyroxine-induced rat testicular oxidative stress.

  Chemico-biological interactions 20081125

• Dose dependence and therapeutic window for the neuroprotective effects of curcumin in thromboembolic model of rat.

  Behavioural brain research 20081121

• Rapid reactive oxygen species (ROS) generation induced by curcumin leads to caspase-dependent and -independent apoptosis in L929 cells.

  Free radical biology & medicine 20081115

• Qualitative and quantitative analysis of four species of Curcuma rhizomes using twice development thin layer chromatography.

  Journal of pharmaceutical and biomedical analysis 20081104

• Involvement of anti-inflammatory heme oxygenase-1 in the inhibitory effect of curcumin on the expression of pro-inflammatory inducible nitric oxide synthase in RAW264.7 macrophages.

  Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20081101

• Synthesis of novel biodegradable and self-assembling methoxy poly(ethylene glycol)-palmitate nanocarrier for curcumin delivery to cancer cells.

  Acta biomaterialia 20081101

• Implication of functional activity for determining therapeutic efficacy of suicide genes in vitro.

  Biotechnology letters 20081101

• Curcumin inhibits VEGF-mediated angiogenesis in human intestinal microvascular endothelial cells through COX-2 and MAPK inhibition.

  Gut 20081101

• Novel role of curcumin in the prevention of cytokine-induced islet death in vitro and diabetogenesis in vivo.

  British journal of pharmacology 20081101

• Polyphenol-induced dissociation of various amyloid fibrils results in a methionine-independent formation of ROS.

  Biochimica et biophysica acta 20081101

• Effect of antioxidant phytochemicals on the hepatic tumor promoting activity of 3,3',4,4'-tetrachlorobiphenyl (PCB-77).

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20081101

• Sodium arsenite induced biochemical perturbations in rats: ameliorating effect of curcumin.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20081101

• Limited effects of dietary curcumin on Th-1 driven colitis in IL-10 deficient mice suggest an IL-10-dependent mechanism of protection.

  American journal of physiology. Gastrointestinal and liver physiology 20081101

• Beneficial effects of curcumin on hyperlipidemia and insulin resistance in high-fat-fed hamsters.

  Metabolism: clinical and experimental 20081101

• An update on the dietary ligands of the AhR.

  Expert opinion on drug metabolism & toxicology 20081101

• Niemann-Pick disease type C1 is a sphingosine storage disease that causes deregulation of lysosomal calcium.

  Nature medicine 20081101

• Curcumin protects Leydig cells of mice from damage induced by chronic alcohol administration.

  Medical science monitor : international medical journal of experimental and clinical research 20081101

• Curcuminoids modulates oxidative damage and mitochondrial dysfunction in diabetic rat brain.

  Free radical research 20081101

• Inhibitory effect of dehydrozingerone on vascular smooth muscle cell function.

  Journal of cardiovascular pharmacology 20081101

• [The study of insulin resistance and leptin resistance on the model of simplicity obesity rats by curcumin].

  Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] 20081101

• [Hereditary neuropathy: recent advance].

  Rinsho shinkeigaku = Clinical neurology 20081101

• [Study on stability of curcumine, demethoxycurcumin and bisdemethoxycurcumin].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20081101

• [Preliminary study on molecular mechanism of curcumine anti-mouse melanoma].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20081101

• Femtosecond laser processing of biopolymers at high repetition rate.

  Physical chemistry chemical physics : PCCP 20081028

• Effect of curcumin analog on gamma-radiation-induced cellular changes in primary culture of isolated rat hepatocytes in vitro.

  Chemico-biological interactions 20081022

• Purification of curcumin, demethoxycurcumin, and bisdemethoxycurcumin by high-speed countercurrent chromatography.

  Journal of agricultural and food chemistry 20081022

• Curcumin attenuates ovalbumin-induced airway inflammation by regulating nitric oxide.

  Biochemical and biophysical research communications 20081017

• Aminostyrylbenzofuran derivatives as potent inhibitors for Abeta fibril formation.

  Bioorganic & medicinal chemistry letters 20081015

• Curcumin inhibits proliferation, invasion, angiogenesis and metastasis of different cancers through interaction with multiple cell signaling proteins.

  Cancer letters 20081008

• Quantitation of curcuminoids in curcuma rhizome by near-infrared spectroscopic analysis.

  Journal of agricultural and food chemistry 20081008

• Curcumin attenuates EGF-induced AQP3 up-regulation and cell migration in human ovarian cancer cells.

  Cancer chemotherapy and pharmacology 20081001

• Comparison between chondroprotective effects of glucosamine, curcumin, and diacerein in IL-1beta-stimulated C-28/I2 chondrocytes.

  Osteoarthritis and cartilage 20081001

• Curcumin protects dopaminergic neuron against LPS induced neurotoxicity in primary rat neuron/glia culture.

  Neurochemical research 20081001

• Potential protection of curcumin against hypoxia-induced decreases in beta-III tubulin content in rat prefrontal cortical neurons.

  Neurochemical research 20081001

• Areca nut extract represses migration and differentiation while activating matrix metalloproteinase-9 of normal gingival epithelial cells.

  Journal of periodontal research 20081001

• Fluorescence study of the curcumin-casein micelle complexation and its application as a drug nanocarrier to cancer cells.

  Biomacromolecules 20081001

• Liposome-encapsulated curcumin suppresses growth of head and neck squamous cell carcinoma in vitro and in xenografts through the inhibition of nuclear factor kappaB by an AKT-independent pathway.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20081001

• Curcumin suppresses constitutive activation of nuclear factor-kappa B and requires functional Bax to induce apoptosis in Burkitt's lymphoma cell lines.

  Molecular cancer therapeutics 20081001

• Induction of cytochromes P450 in small intestine by chemopreventive compounds.

  Neuro endocrinology letters 20081001

• Protective effect of dietary phytochemicals against arsenite induced genotoxicity in mammalian V79 cells.

  Indian journal of experimental biology 20081001

• Curcumin-induced recovery from hepatic injury involves induction of apoptosis of activated hepatic stellate cells.

  Indian journal of biochemistry & biophysics 20081001

• Curcumin inhibition of integrin (alpha6beta4)-dependent breast cancer cell motility and invasion.

  Cancer prevention research (Philadelphia, Pa.) 20081001

• The effect of curcumin on lipid level in patients with acute coronary syndrome.

  Acta medica Indonesiana 20081001

• [Fingerprint of Curcuma phaeocaulis by LC-MS].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20081001

• Curcumin inhibits the increase of glutamate, hydroxyl radicals and PGE2 in the hypothalamus and reduces fever during LPS-induced systemic inflammation in rabbits.

  European journal of pharmacology 20080928

• Curcumin prevents human dendritic cell response to immune stimulants.

  Biochemical and biophysical research communications 20080926

• Cobalt chloride attenuates hypobaric hypoxia induced vascular leakage in rat brain: molecular mechanisms of action of cobalt chloride.

  Toxicology and applied pharmacology 20080915

• Curcumin protects cardiac cells against ischemia-reperfusion injury: effects on oxidative stress, NF-kappaB, and JNK pathways.

  Free radical biology & medicine 20080915

• Curcumin inhibits the proteasome activity in human colon cancer cells in vitro and in vivo.

  Cancer research 20080915

• Curcumin inhibits lung cancer cell invasion and metastasis through the tumor suppressor HLJ1.

  Cancer research 20080915

• Neuroprotective effect of curcumin on transient focal cerebral ischemia in rats.

  Brain research 20080910

• Recent advances in plant hepatoprotectives: a chemical and biological profile of some important leads.

  Medicinal research reviews 20080901

• Effect of pure curcumin, demethoxycurcumin, and bisdemethoxycurcumin on WT1 gene expression in leukemic cell lines.

  Cancer chemotherapy and pharmacology 20080901

• Curcumin ameliorates aflatoxin-induced toxicity in mice spermatozoa.

  Fertility and sterility 20080901

• Curcumin in cancer management: recent results of analogue design and clinical studies and desirable future research.

  Molecular nutrition & food research 20080901

• Design, synthesis and characterization of some bioactive conjugates of curcumin with glycine, glutamic acid, valine and demethylenated piperic acid and study of their antimicrobial and antiproliferative properties.

  European journal of medicinal chemistry 20080901

• The upregulation of heat shock protein 70 expression in areca quid chewing-associated oral squamous cell carcinomas.

  Oral oncology 20080901

• Early anti-oxidative and anti-proliferative curcumin effects on neuroglioma cells suggest therapeutic targets.

  Neurochemical research 20080901

• Modulation of steroid activity in chronic inflammation: a novel anti-inflammatory role for curcumin.

  Molecular nutrition & food research 20080901

• Multi-targeted therapy by curcumin: how spicy is it?

  Molecular nutrition & food research 20080901

• Effect of curcumin supplementation on blood glucose, plasma insulin, and glucose homeostasis related enzyme activities in diabetic db/db mice.

  Molecular nutrition & food research 20080901

• Immunomodulatory effects of curcumin in allergy.

  Molecular nutrition & food research 20080901

• Curcumin restores corticosteroid function in monocytes exposed to oxidants by maintaining HDAC2.

  American journal of respiratory cell and molecular biology 20080901

• Murine prostate cancer inhibition by dietary phytochemicals--curcumin and phenyethylisothiocyanate.

  Pharmaceutical research 20080901

• Differential stripping demonstrates a significant reduction of the hair follicle reservoir in vitro compared to in vivo.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20080901

• 15-deoxy-Delta(12,14)-prostaglandin J(2) and curcumin modulate the expression of toll-like receptors 4 and 9 in autoimmune T lymphocyte.

  Journal of clinical immunology 20080901

• Dimethoxycurcumin, a synthetic curcumin analogue with higher metabolic stability, inhibits NO production, inducible NO synthase expression and NF-kappaB activation in RAW264.7 macrophages activated with LPS.

  Molecular nutrition & food research 20080901

• The bound states of amphipathic drugs in lipid bilayers: study of curcumin.

  Biophysical journal 20080901

• Inhibition of IkappaB kinase-nuclear factor-kappaB signaling pathway by 3,5-bis(2-flurobenzylidene)piperidin-4-one (EF24), a novel monoketone analog of curcumin.

  Molecular pharmacology 20080901

• Bioavailability enhancement and targeting of stomach tumors using gastro-retentive floating drug delivery system of curcumin--'a technical note'.

  AAPS PharmSciTech 20080901

• Quercetin inhibition of tumor invasion via suppressing PKC delta/ERK/AP-1-dependent matrix metalloproteinase-9 activation in breast carcinoma cells.

  Carcinogenesis 20080901

• Androgen receptor is a new potential therapeutic target for the treatment of hepatocellular carcinoma.

  Gastroenterology 20080901

• New mechanisms and therapeutic potential of curcumin for colorectal cancer.

  Molecular nutrition & food research 20080901

• Synthesis and evaluation of curcumin analogues as potential thioredoxin reductase inhibitors.

  Bioorganic & medicinal chemistry 20080901

• Curcumin up-regulates LDL receptor expression via the sterol regulatory element pathway in HepG2 cells.

  Planta medica 20080901

• Androgen responsive and refractory prostate cancer cells exhibit distinct curcumin regulated transcriptome.

  Cancer biology & therapy 20080901

• Metabolism of curcumin and induction of mitotic catastrophe in human cancer cells.

  Molecular nutrition & food research 20080901

• Production of curcuminoids by Escherichia coli carrying an artificial biosynthesis pathway.

  Microbiology (Reading, England) 20080901

• Prostate cancer and curcumin: add spice to your life.

  Cancer biology & therapy 20080901

• Curcumin inhibits Akt/mammalian target of rapamycin signaling through protein phosphatase-dependent mechanism.

  Molecular cancer therapeutics 20080901

• Curcumin: a promising spice for therapeutics.

  Molecular nutrition & food research 20080901

• Curcumin and the cellular stress response in free radical-related diseases.

  Molecular nutrition & food research 20080901

• [Protective effect of curcumin on oleic-induced acute lung injury in rats].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080901

• Epigallocatechin-3-gallate and curcumin suppress amyloid beta-induced beta-site APP cleaving enzyme-1 upregulation.

  Neuroreport 20080827

• Curcumin and cancer: an 'old-age' disease with an 'age-old' solution.

  Cancer letters 20080818

• Synergistic effects of multiple natural products in pancreatic cancer cells.

  Life sciences 20080815

• Exposure to metal ions regulates mRNA levels of APP and BACE1 in PC12 cells: blockage by curcumin.

  Neuroscience letters 20080808

• Abrogation of G2/M arrest sensitizes curcumin-resistant hepatoma cells to apoptosis.

  FEBS letters 20080806

• Micelles of poly(ethylene oxide)-b-poly(epsilon-caprolactone) as vehicles for the solubilization, stabilization, and controlled delivery of curcumin.

  Journal of biomedical materials research. Part A 20080801

• Cytotoxic effects of curcumin on osteosarcoma cell lines.

  Investigational new drugs 20080801

• Structure-activity relationships for the inhibition of recombinant human cytochromes P450 by curcumin analogues.

  European journal of medicinal chemistry 20080801

• Curcumin downregulates H19 gene transcription in tumor cells.

  Journal of cellular biochemistry 20080801

• Different curcuminoids inhibit T-lymphocyte proliferation independently of their radical scavenging activities.

  Pharmaceutical research 20080801

• Curcumin (diferuloylmethane) inhibits cell proliferation, induces apoptosis, and decreases hormone levels and secretion in pituitary tumor cells.

  Endocrinology 20080801

• Curcuminoids inhibit multiple human cytochromes P450, UDP-glucuronosyltransferase, and sulfotransferase enzymes, whereas piperine is a relatively selective CYP3A4 inhibitor.

  Drug metabolism and disposition: the biological fate of chemicals 20080801

• Glucocorticoid receptor phosphorylation differentially affects target gene expression.

  Molecular endocrinology (Baltimore, Md.) 20080801

• Transcriptome analysis provides new insights into liver changes induced in the rat upon dietary administration of the food additives butylated hydroxytoluene, curcumin, propyl gallate and thiabendazole.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20080801

• A novel polyherbal microbicide with inhibitory effect on bacterial, fungal and viral genital pathogens.

  International journal of antimicrobial agents 20080801

• Curcumin protected PC12 cells against beta-amyloid-induced toxicity through the inhibition of oxidative damage and tau hyperphosphorylation.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20080801

• Possible nitric oxide modulation in protective effect of (Curcuma longa, Zingiberaceae) against sleep deprivation-induced behavioral alterations and oxidative damage in mice.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20080801

• Curcumin modulates SDF-1alpha/CXCR4-induced migration of human retinal endothelial cells (HRECs).

  Investigative ophthalmology & visual science 20080801

• Evidence for dietary regulation of microRNA expression in cancer cells.

  Nutrition reviews 20080801

• Potential role of curcumin in stroke prevention.

  Expert review of neurotherapeutics 20080801

• Dietary polyphenols mediated regulation of oxidative stress and chromatin remodeling in inflammation.

  Nutrition reviews 20080801

• EF24, a novel curcumin analog, disrupts the microtubule cytoskeleton and inhibits HIF-1.

  Cell cycle (Georgetown, Tex.) 20080801

• Inhibition of thioredoxin reductase by curcumin analogs.

  Bioscience, biotechnology, and biochemistry 20080801

• Curcumin prevents and reverses cirrhosis induced by bile duct obstruction or CCl4 in rats: role of TGF-beta modulation and oxidative stress.

  Fundamental & clinical pharmacology 20080801

• [Antiproliferative effect of curcumin combined with cyclophosmide on the growth of human lymphoma cell line HT/CTX with drug resistance and its relation with FA/BRCA pathway].

  Zhongguo shi yan xue ye xue za zhi 20080801

• In vitro release of curcumin from vehicles containing alginate and cyclodextrin. Studies of curcumin and curcuminoides. XXXIII.

  Die Pharmazie 20080801

• [Influence of curcumin--loaded poly (lactide-co-glycolide) films on the proliferation of vascular smooth muscle cells].

  Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi 20080801

• [Curcumin inhibits growth, induces G1 arrest and apoptosis on human prostatic stromal cells by regulating Bcl-2/Bax].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080801

• [Curcumin inhibiting the expression of indoleamine 2,3-dioxygenase induced by IFN-gamma in cancer cells].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20080801

• Concentration dependent antioxidant/pro-oxidant activity of curcumin studies from AAPH induced hemolysis of RBCs.

  Chemico-biological interactions 20080730

• Phase II trial of curcumin in patients with advanced pancreatic cancer.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20080715

• Antioxidant and radical scavenging properties of curcumin.

  Chemico-biological interactions 20080710

• Is there a role for herbal medicine in the treatment of pancreatic cancer?. Highlights from the '44th ASCO Annual Meeting'. Chicago, IL, USA. May 30 - June 3, 2008.

  JOP : Journal of the pancreas 20080710

• Protective role of curcumin against nicotine-induced genotoxicity on rat liver under restricted dietary protein.

  European journal of pharmacology 20080707

• Curcumin attenuates indomethacin-induced oxidative stress and mitochondrial dysfunction.

  Archives of toxicology 20080701

• Hormetic modulation of differentiation of normal human epidermal keratinocytes undergoing replicative senescence in vitro.

  Experimental gerontology 20080701

• Effects of spice constituents on P-glycoprotein-mediated transport and CYP3A4-mediated metabolism in vitro.

  Drug metabolism and disposition: the biological fate of chemicals 20080701

• Curcumin induces cell-arrest and apoptosis in association with the inhibition of constitutively active NF-kappaB and STAT3 pathways in Hodgkin's lymphoma cells.

  International journal of cancer 20080701

• Dietary curcumin significantly improves obesity-associated inflammation and diabetes in mouse models of diabesity.

  Endocrinology 20080701

• Inhibition of Nod2 signaling and target gene expression by curcumin.

  Molecular pharmacology 20080701

• Synergistic effects of the purine analog sulfinosine and curcumin on the multidrug resistant human non-small cell lung carcinoma cell line (NCI-H460/R).

  Cancer biology & therapy 20080701

• Curcumin structure-function, bioavailability, and efficacy in models of neuroinflammation and Alzheimer's disease.

  The Journal of pharmacology and experimental therapeutics 20080701

• Coupling endoplasmic reticulum stress to the cell death program in mouse melanoma cells: effect of curcumin.

  Apoptosis : an international journal on programmed cell death 20080701

• Reactive oxygen species and imbalance of calcium homeostasis contributes to curcumin induced programmed cell death in Leishmania donovani.

  Apoptosis : an international journal on programmed cell death 20080701

• Effect of curcumin on the adhesion of platelets to brain microvascular endothelial cells in vitro.

  Acta pharmacologica Sinica 20080701

• Tetrahydrocurcumin inhibits HT1080 cell migration and invasion via downregulation of MMPs and uPA.

  Acta pharmacologica Sinica 20080701

• Syntheses and cytotoxic properties of the curcumin analogs 2,6-bis(benzylidene)-4-phenylcyclohexanones.

  Archiv der Pharmazie 20080701

• Nrf2 regulates curcumin-induced aldose reductase expression indirectly via nuclear factor-kappaB.

  Pharmacological research 20080701

• Curcumin blocks RON tyrosine kinase-mediated invasion of breast carcinoma cells.

  Cancer research 20080701

• Curcumin decreases specificity protein expression in bladder cancer cells.

  Cancer research 20080701

• [Effects of curcumin on secretion of adiponectin and interleukin-6 in human adipose tissues: an in vitro study].

  Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20080701

• The biosynthetic pathway of curcuminoid in turmeric (Curcuma longa) as revealed by 13C-labeled precursors.

  Bioscience, biotechnology, and biochemistry 20080701

• Modulatory effect of curcumin on methionine-induced hyperlipidemia and hyperhomocysteinemia in albino rats.

  Indian journal of experimental biology 20080701

• Curcumin alleviates dystrophic muscle pathology in mdx mice.

  Molecules and cells 20080630

• Curcuma drugs and curcumin regulate the expression and function of P-gp in Caco-2 cells in completely opposite ways.

  International journal of pharmaceutics 20080624

• Effects of curcumin on bladder cancer cells and development of urothelial tumors in a rat bladder carcinogenesis model.

  Cancer letters 20080618

• Curcumin inhibits bTREK-1 K+ channels and stimulates cortisol secretion from adrenocortical cells.

  Biochemical and biophysical research communications 20080613

• Encapsulation of curcumin in cationic micelles suppresses alkaline hydrolysis.

  Langmuir : the ACS journal of surfaces and colloids 20080603

• Anti-inflammation activities of essential oil and its constituents from indigenous cinnamon (Cinnamomum osmophloeum) twigs.

  Bioresource technology 20080601

• Protective effects of dietary curcumin in mouse model of chemically induced colitis are strain dependent.

  Inflammatory bowel diseases 20080601

• Anti-ischemic effect of curcumin in rat brain.

  Neurochemical research 20080601

• Membrane-thinning effect of curcumin.

  Biophysical journal 20080601

• Curcumin: from ancient medicine to current clinical trials.

  Cellular and molecular life sciences : CMLS 20080601

• Heme oxygenase-1 mediates the anti-inflammatory effect of Curcumin within LPS-stimulated human monocytes.

  Journal of cellular physiology 20080601

• Curcumin protects against ischemia/reperfusion injury in rat kidneys.

  World journal of urology 20080601

• Plasmodium chabaudi: efficacy of artemisinin + curcumin combination treatment on a clone selected for artemisinin resistance in mice.

  Experimental parasitology 20080601

• Curcumin induces apoptosis in HCT-116 human colon cancer cells in a p21-independent manner.

  Experimental and molecular pathology 20080601

• Development of curcuminoids hydrogel patch using chitosan from various sources as controlled-release matrix.

  International journal of cosmetic science 20080601

• Curcumin decreases 12-O-tetradecanoylphorbol-13-acetate-induced protein kinase C translocation to modulate downstream targets in mouse skin.

  Carcinogenesis 20080601

• Efficacy of turmeric (Curcuma longa), containing a known level of curcumin, and a hydrated sodium calcium aluminosilicate to ameliorate the adverse effects of aflatoxin in broiler chicks.

  Poultry science 20080601

• Anticancer and carcinogenic properties of curcumin: considerations for its clinical development as a cancer chemopreventive and chemotherapeutic agent.

  Molecular nutrition & food research 20080601

• Fiber diffraction as a screen for amyloid inhibitors.

  Current Alzheimer research 20080601

• Natural compounds with proteasome inhibitory activity for cancer prevention and treatment.

  Current protein & peptide science 20080601

• Pharmacokinetics of curcumin conjugate metabolites in healthy human subjects.

  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20080601

• Effect of butylated hydroxytoluene, curcumin, propyl gallate and thiabendazole on cytochrome P450 forms in cultured human hepatocytes.

  Xenobiotica; the fate of foreign compounds in biological systems 20080601

• [Curcumin promotes apoptosis of esophageal squamous carcinoma cell lines through inhibition of NF-kappaB signaling pathway].

  Ai zheng = Aizheng = Chinese journal of cancer 20080601

• Curcumin or saikosaponin a improves hepatic antioxidant capacity and protects against CCl4-induced liver injury in rats.

  Journal of medicinal food 20080601

• [Effects of curcumin on bleomycin-induced damages in pulmonary functions in rats].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080601

• Curcumin attenuates methotraxate-induced hepatic oxidative damage in rats.

  Journal of the Egyptian National Cancer Institute 20080601

• Alleviation of enhanced oxidative stress and oxygen consumption of L-thyroxine induced hyperthyroid rat liver mitochondria by vitamin E and curcumin.

  Chemico-biological interactions 20080528

• Extraction, processing, and storage effects on curcuminoids and oleoresin yields from Curcuma longa L. grown in Jamaica.

  Journal of agricultural and food chemistry 20080528

• Curcumin stimulates proliferation of embryonic neural progenitor cells and neurogenesis in the adult hippocampus.

  The Journal of biological chemistry 20080523

• Curcumin protects against glutamate excitotoxicity in rat cerebral cortical neurons by increasing brain-derived neurotrophic factor level and activating TrkB.

  Brain research 20080519

• Antioxidant and iron-binding properties of curcumin, capsaicin, and S-allylcysteine reduce oxidative stress in rat brain homogenate.

  Journal of agricultural and food chemistry 20080514

• Molecularly imprinted poly (methacrylamide-co-methacrylic acid) composite membranes for recognition of curcumin.

  Analytica chimica acta 20080512

• Curry compound fights cancer in the clinic.

  Journal of the National Cancer Institute 20080507

• Curcumin improves learning and memory ability and its neuroprotective mechanism in mice.

  Chinese medical journal 20080505

• Apoptotic induction with bifunctional E.coli cytosine deaminase-uracil phosphoribosyltransferase mediated suicide gene therapy is synergized by curcumin treatment in vitro.

  Molecular biotechnology 20080501

• The combination of epigallocatechin gallate and curcumin suppresses ER alpha-breast cancer cell growth in vitro and in vivo.

  International journal of cancer 20080501

• A broadly neuroprotective derivative of curcumin.

  Journal of neurochemistry 20080501

• Curcumin inhibits glucose production in isolated mice hepatocytes.

  Diabetes research and clinical practice 20080501

• The chemopreventive agent curcumin is a potent radiosensitizer of human cervical tumor cells via increased reactive oxygen species production and overactivation of the mitogen-activated protein kinase pathway.

  Molecular pharmacology 20080501

• Synergistic effect of erythropoietin but not G-CSF in combination with curcumin on impaired liver regeneration in rats.

  Langenbeck's archives of surgery 20080501

• Dietary curcumin modulates transcriptional regulators of phase I and phase II enzymes in benzo[a]pyrene-treated mice: mechanism of its anti-initiating action.

  Carcinogenesis 20080501

• Activation of peroxisome proliferator-activated receptor-gamma by curcumin blocks the signaling pathways for PDGF and EGF in hepatic stellate cells.

  Laboratory investigation; a journal of technical methods and pathology 20080501

• Immunomodulatory effects of curcumin: in-vivo.

  International immunopharmacology 20080501

• Curcumin, a constituent of curry, suppresses IgE-mediated allergic response and mast cell activation at the level of Syk.

  The Journal of allergy and clinical immunology 20080501

• Evaluation of a nanotechnology-based carrier for delivery of curcumin in prostate cancer cells.

  International journal of oncology 20080501

• Curcumin inhibits cellular cholesterol accumulation by regulating SREBP-1/caveolin-1 signaling pathway in vascular smooth muscle cells.

  Acta pharmacologica Sinica 20080501

• Sulphur and nitrogen regulation of the protease-encoding ACP1 gene in the fungus Botrytis cinerea: correlation with a phospholipase D activity.

  Microbiology (Reading, England) 20080501

• Characterization and bioavailability of liposomes containing a ukon extract.

  Bioscience, biotechnology, and biochemistry 20080501

• Novel anti-angiogenic compounds for application in tumor therapy - COP9 signalosome-associated kinases as possible targets.

  Mini reviews in medicinal chemistry 20080501

• [Effect of curcumin on the expression of collagen type I protein and transforming growth factor-beta1 mRNA in pulmonary fibrosis rats].

  Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20080501

• Antioxidants prevent ethanol-associated apoptosis in fetal rhombencephalic neurons.

  Brain research 20080414

• Curcumin inhibits herpes simplex virus immediate-early gene expression by a mechanism independent of p300/CBP histone acetyltransferase activity.

  Virology 20080410

• Anti-cancer and anti-angiogenic effects of curcumin and tetrahydrocurcumin on implanted hepatocellular carcinoma in nude mice.

  World journal of gastroenterology 20080407

• Inhibitory effect of compounds from Zingiberaceae species on human platelet aggregation.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20080401

• Opposing effects of curcuminoids on serum stimulated and unstimulated angiogenic response.

  Journal of cellular physiology 20080401

• Ultrasound-assisted reaction of 2,3,4,6-tetra-O-acetyl-alpha-D-glucopyranosyl bromide with potassium salt of curcumin under PTC conditions.

  Ultrasonics sonochemistry 20080401

• Curcumin downregulates the inflammatory cytokines CXCL1 and -2 in breast cancer cells via NFkappaB.

  Carcinogenesis 20080401

• Curcumin attenuates dimethylnitrosamine-induced liver injury in rats through Nrf2-mediated induction of heme oxygenase-1.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20080401

• GSK-3beta regulates cyclin D1 expression: a new target for chemotherapy.

  Cellular signalling 20080401

• Quantitative cellular uptake, localization and cytotoxicity of curcumin in normal and tumor cells.

  Biochimica et biophysica acta 20080401

• Curcumin inhibits aggregation of alpha-synuclein.

  Acta neuropathologica 20080401

• Mitochondrial reactive oxygen species affect sensitivity to curcumin-induced apoptosis.

  Free radical biology & medicine 20080401

• Oral curcumin in the treatment of moderate to severe psoriasis vulgaris: A prospective clinical trial.

  Journal of the American Academy of Dermatology 20080401

• Synthesis of curcumin mimics with multidrug resistance reversal activities.

  Bioorganic & medicinal chemistry 20080401

• Curcumin inhibits NFkappaB mediated radioprotection and modulate apoptosis related genes in human neuroblastoma cells.

  Cancer biology & therapy 20080401

• Cyto-protective and immunomodulating effect of Curcuma longa in Wistar rats subjected to carbon tetrachloride-induced oxidative stress.

  Inflammopharmacology 20080401

• Anesthetics and natural heme oxygenase-1 inducers: waiting for carbon monoxide?

  Annals of surgery 20080401

• Preventive effects of curcumin and dexamethasone on lung transplantation-associated lung injury in rats.

  Critical care medicine 20080401

• Curcumin sensitizes human colorectal cancer xenografts in nude mice to gamma-radiation by targeting nuclear factor-kappaB-regulated gene products.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20080401

• [Effect and mechanism of curcumin on learning and memory dysfunction induced by gp120 in rats].

  Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20080401

• Inhibition of monoamine oxidase-B by the polyphenolic compound, curcumin and its metabolite tetrahydrocurcumin, in a model of Parkinson's disease induced by MPTP neurodegeneration in mice.

  Inflammopharmacology 20080401

• Targeting the lipopolysaccharides: still a matter of debate?

  Current opinion in anaesthesiology 20080401

• Comparison of suppressive effects of demethoxycurcumin and bisdemethoxycurcumin on expressions of inflammatory mediators in vitro and in vivo.

  Archives of pharmacal research 20080401

• Role of curcumin in health and disease.

  Archives of physiology and biochemistry 20080401

• [Preparation and study in vitro of long-circulating nanoliposomes of curcumin].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080401

• [Study on effect of demethoxycurcumin in Curcuma long on stability of curcumin].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20080401

• Effect of melatonin, curcumin, quercetin, and resveratrol on acute ferric nitrilotriacetate (Fe-NTA)-induced renal oxidative damage in rats.

  Human & experimental toxicology 20080401

• Curcumin, a known phenolic from Curcuma longa, attenuates the virulence of Pseudomonas aeruginosa PAO1 in whole plant and animal pathogenicity models.

  Journal of agricultural and food chemistry 20080326

• Loading of curcumin into macrophages using lipid-based nanoparticles.

  International journal of pharmaceutics 20080320

• Spectroscopic and theoretical study of the electronic structure of curcumin and related fragment molecules.

  The journal of physical chemistry. A 20080320

• Synthesis and exploration of novel curcumin analogues as anti-malarial agents.

  Bioorganic & medicinal chemistry 20080315

• Ultrasound mediates the release of curcumin from microemulsions.

  Langmuir : the ACS journal of surfaces and colloids 20080304

• Curcumin prevents and reverses murine cardiac hypertrophy.

  The Journal of clinical investigation 20080303

• Currying favor for the heart.

  The Journal of clinical investigation 20080303

• The dietary compound curcumin inhibits p300 histone acetyltransferase activity and prevents heart failure in rats.

  The Journal of clinical investigation 20080303

• Roles for CSN5 in control of p53/MDM2 activities.

  Journal of cellular biochemistry 20080301

• Beneficial drugs for liver diseases.

  Journal of applied toxicology : JAT 20080301

• Curcumin binds to the alpha-helical intermediate and to the amyloid form of prion protein - a new mechanism for the inhibition of PrP(Sc) accumulation.

  Journal of neurochemistry 20080301

• Cancer chemoprevention through dietary antioxidants: progress and promise.

  Antioxidants & redox signaling 20080301

• Curcumin treatment alleviates the effects of glutathione depletion in vitro and in vivo: therapeutic implications for Parkinson's disease explained via in silico studies.

  Free radical biology & medicine 20080301

• Change in post-translational modifications of histone H3, heat-shock protein-27 and MAP kinase p38 expression by curcumin in streptozotocin-induced type I diabetic nephropathy.

  British journal of pharmacology 20080301

• The potential use of curcumin in management of chronic disease: too good to be true?

  Current opinion in gastroenterology 20080301

• p21 Waf1/Cip1 expression by curcumin in U-87MG human glioma cells: role of early growth response-1 expression.

  Cancer research 20080301

• Curcumin (diferuloylmethane) alters the expression profiles of microRNAs in human pancreatic cancer cells.

  Molecular cancer therapeutics 20080301

• Curcumin: preventive and therapeutic properties in laboratory studies and clinical trials.

  Antioxidants & redox signaling 20080301

• Effect of tetrahydrocurcumin on insulin receptor status in type 2 diabetic rats: studies on insulin binding to erythrocytes.

  Journal of biosciences 20080301

• [Studies on solubility enhancement of curcumin by Polyvinylpyrrolidione K30].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20080301

• Curcumin as 'Curecumin': from kitchen to clinic.

  Biochemical pharmacology 20080215

• Curcumin inhibits FtsZ assembly: an attractive mechanism for its antibacterial activity.

  The Biochemical journal 20080215

• Curcumin protects against cytotoxic and inflammatory effects of quartz particles but causes oxidative DNA damage in a rat lung epithelial cell line.

  Toxicology and applied pharmacology 20080215

• Synthesis and anti-inflammatory activities of mono-carbonyl analogues of curcumin.

  Bioorganic & medicinal chemistry letters 20080215

• Curcumin induces apoptosis through an ornithine decarboxylase-dependent pathway in human promyelocytic leukemia HL-60 cells.

  Life sciences 20080213

• Curcumin inhibits connective tissue growth factor gene expression in activated hepatic stellate cells in vitro by blocking NF-kappaB and ERK signalling.

  British journal of pharmacology 20080201

• Electrogenic steps of the SR Ca-ATPase enzymatic cycle and the effect of curcumin.

  Biochimica et biophysica acta 20080201

• Curcumin protects the rat liver from CCl4-caused injury and fibrogenesis by attenuating oxidative stress and suppressing inflammation.

  Molecular pharmacology 20080201

• Protective effect of Curcumin, the active principle of turmeric (Curcuma longa) in haloperidol-induced orofacial dyskinesia and associated behavioural, biochemical and neurochemical changes in rat brain.

  Pharmacology, biochemistry, and behavior 20080201

• Investigating the binding of curcumin derivatives to bovine serum albumin.

  Biophysical chemistry 20080201

• Curcumin: potential for hepatic fibrosis therapy?

  British journal of pharmacology 20080201

• Pancreatic cancer cell genetics and signaling response to treatment correlate with efficacy of gemcitabine-based molecular targeting strategies.

  Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20080201

• Evaluation of drugs for treatment of prion infections of the central nervous system.

  The Journal of general virology 20080201

• Six-month randomized, placebo-controlled, double-blind, pilot clinical trial of curcumin in patients with Alzheimer disease.

  Journal of clinical psychopharmacology 20080201

• Delayed disruption of barrier function in cultured human corneal epithelial cells induced by tumor necrosis factor-alpha in a manner dependent on NF-kappaB.

  Investigative ophthalmology & visual science 20080201

• Synthesis and anti-bacterial properties of mono-carbonyl analogues of curcumin.

  Chemical & pharmaceutical bulletin 20080201

• Prolactin and growth hormone induce differential cytokine and chemokine profile in murine peritoneal macrophages in vitro: involvement of p-38 MAP kinase, STAT3 and NF-kappaB.

  Cytokine 20080201

• Genome-wide drug-induced haploinsufficient screening of fission yeast for identification of hydrazinocurcumin targets.

  Journal of microbiology and biotechnology 20080201

• [Curcumin inhibits the expression of vascular endothelial growth factor and androgen-independent prostate cancer cell line PC-3 in vitro].

  Zhonghua nan ke xue = National journal of andrology 20080201

• [Preparation and anticoagulation of curcumin/poly(lactic acid-co-glycol acid) composite films].

  Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi 20080201

• [Effect of curcumin on invasion and migration of tongue squamous cell carcinoma cell line Tca8113].

  Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology 20080201

• Isolation and identification of an anti-tumor component from leaves of Impatiens balsamina.

  Molecules (Basel, Switzerland) 20080131

• Simultaneous determination of hydrazinocurcumin and phenol red in samples from rat intestinal permeability studies: HPLC method development and validation.

  Journal of pharmaceutical and biomedical analysis 20080122

• Microwave assisted extraction of curcumin by sample-solvent dual heating mechanism using Taguchi L9 orthogonal design.

  Journal of pharmaceutical and biomedical analysis 20080122

• Treatment of inflammatory bowel disease: a review of medical therapy.

  World journal of gastroenterology 20080121

• Curcumin down-regulates the multidrug-resistance mdr1b gene by inhibiting the PI3K/Akt/NF kappa B pathway.

  Cancer letters 20080118

• Curcumin treatment enhances islet recovery by induction of heat shock response proteins, Hsp70 and heme oxygenase-1, during cryopreservation.

  Life sciences 20080116

• Curcumin enhances the effects of 5-fluorouracil and oxaliplatin in mediating growth inhibition of colon cancer cells by modulating EGFR and IGF-1R.

  International journal of cancer 20080115

• Alterations in mitochondrial respiratory functions, redox metabolism and apoptosis by oxidant 4-hydroxynonenal and antioxidants curcumin and melatonin in PC12 cells.

  Toxicology and applied pharmacology 20080115

• Antitumor effects of curcumin and structurally beta-diketone modified analogs on multidrug resistant cancer cells.

  Bioorganic & medicinal chemistry letters 20080115

• The effect of curcumin (active substance of turmeric) on the acetic acid-induced visceral nociception in rats.

  Pakistan journal of biological sciences : PJBS 20080115

• The antidepressant effects of curcumin in the forced swimming test involve 5-HT1 and 5-HT2 receptors.

  European journal of pharmacology 20080106

• Chemoprevention with special reference to inherited colorectal cancer.

  Familial cancer 20080101

• Inhibitory effect of curcuminoids and tetrahydrocurcuminoids on equine activated neutrophils and myeloperoxidase activity.

  Physiological research 20080101

• Separation and free radical-scavenging activity of major curcuminoids of Curcuma longa using HPTLC-DPPH method.

  Phytochemical analysis : PCA 20080101

• Studies on the interaction of isoxazolcurcumin with calf thymus DNA.

  International journal of biological macromolecules 20080101

• Curcumin-derived pyrazoles and isoxazoles: Swiss army knives or blunt tools for Alzheimer's disease?

  ChemMedChem 20080101

• Induction of full-length survival motor neuron by polyphenol botanical compounds.

  Human genetics 20080101

• Cell cycle control as a basis for cancer chemoprevention through dietary agents.

  Frontiers in bioscience : a journal and virtual library 20080101

• Two immunomodulators, curcumin and sulfasalazine, enhance IDV antiretroviral activity in HIV-1 persistently infected cells.

  Archives of virology 20080101

• High glucose enhances lipopolysaccharide-stimulated CD14 expression in U937 mononuclear cells by increasing nuclear factor kappaB and AP-1 activities.

  The Journal of endocrinology 20080101

• Roles of MAPK and NF-kappaB in interleukin-6 induction by lipopolysaccharide in vascular smooth muscle cells.

  Journal of cardiovascular pharmacology 20080101

• Curcumin sensitizes TRAIL-resistant xenografts: molecular mechanisms of apoptosis, metastasis and angiogenesis.

  Molecular cancer 20080101

• [Protective effect of curcumin against methotrexate-induced small intestinal damage in rats].

  Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20080101

• Compositions for treatment of cancer and inflammation.

  Recent patents on anti-cancer drug discovery 20080101

• [Curcumin in the treatment of prostatic diseases].

  Zhonghua nan ke xue = National journal of andrology 20080101

• [Role of activator protein-1 in pathogenesis of silicosis: an in-vitro study].

  Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20080101

• Effect of curcumin on ipsilateral and contralateral testes after unilateral testicular torsion in a rat model.

  Urologia internationalis 20080101

• CD147 regulates vascular endothelial growth factor-A expression, tumorigenicity, and chemosensitivity to curcumin in hepatocellular carcinoma.

  IUBMB life 20080101

• Curcumin induces apoptosis in human neuroblastoma cells via inhibition of NFkappaB.

  Anticancer research 20080101

• The NF-kappaB inhibitor curcumin blocks sepsis-induced muscle proteolysis.

  Mediators of inflammation 20080101

• Curcumin inhibits WEHI-3 leukemia cells in BALB/c mice in vivo.

  In vivo (Athens, Greece) 20080101

• Curcumin inhibits MPA-induced secretion of VEGF from T47-D human breast cancer cells.

  Menopause (New York, N.Y.) 20080101

• Inhibitory effect of curcumin on corneal neovascularization in vitro and in vivo.

  Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 20080101

• Comparative anti-inflammatory activities of curcumin and tetrahydrocurcumin based on the phenolic O-H bond dissociation enthalpy, ionization potential and quantum chemical descriptor.

  Anticancer research 20080101

• Age-dependent different action of curcumin in thyroid of rat.

  Folia histochemica et cytobiologica 20080101

• Curcumin and resveratrol inhibit nuclear factor-kappaB-mediated cytokine expression in adipocytes.

  Nutrition & metabolism 20080101

• Effect of NCB-02, atorvastatin and placebo on endothelial function, oxidative stress and inflammatory markers in patients with type 2 diabetes mellitus: a randomized, parallel-group, placebo-controlled, 8-week study.

  Drugs in R&D 20080101

• Ameliorative effect of curcumin on aflatoxin-induced toxicity in serum of mice.

  Acta poloniae pharmaceutica 20080101

• Curcumin ameliorates aflatoxin-induced lipid-peroxidation in liver and kidney of mice.

  Acta poloniae pharmaceutica 20080101

• Curcumin blocks the activation of androgen and interlukin-6 on prostate-specific antigen expression in human prostatic carcinoma cells.

  Journal of andrology 20080101

• Curcumin attenuates the organ dysfunction caused by endotoxemia in the rat.

  Nutrition (Burbank, Los Angeles County, Calif.) 20080101

• Design and development of curcumin bioconjugates as antiviral agents.

  Nucleic acids symposium series (2004) 20080101

• Anti-inflammatory activity of curcumin in macrophages stimulated by lipopolysaccharides from Porphyromonas gingivalis.

  Pharmacology 20080101

• Skeletal muscle diseases, inflammation, and NF-kappaB signaling: insights and opportunities for therapeutic intervention.

  International reviews of immunology 20080101

• Curcumin inhibits glyoxalase 1: a possible link to its anti-inflammatory and anti-tumor activity.

  PloS one 20080101

• Interaction of curcumin with intravenous immunoglobulin: a fluorescence quenching and Fourier transformation infrared spectroscopy study.

  Immunobiology 20080101

• Standardization of the ayurvedic formulation Haridra Khanda using high-performance thin-layer chromatography-densitometry.

  Journal of AOAC International 20080101

• Differential solubility of curcuminoids in serum and albumin solutions: implications for analytical and therapeutic applications.

  BMC biotechnology 20080101

• Prevention and treatment of pancreatic cancer by curcumin in combination with omega-3 fatty acids.

  Nutrition and cancer 20080101

• Curcumin ameliorates aflatoxin-induced changes in SDH and ATPase activities in liver and kidney of mice.

  Acta poloniae pharmaceutica 20080101

• Immune defects in Alzheimer's disease: new medications development.

  BMC neuroscience 20080101

• Suppressive effect of hydroquinone, a benzene metabolite, on in vitro inflammatory responses mediated by macrophages, monocytes, and lymphocytes.

  Mediators of inflammation 20080101

• Effects of curcumin on N-bis(2-hydroxypropyl) nitrosamine (DHPN)-induced lung and liver tumorigenesis in BALB/c mice in vivo.

  In vivo (Athens, Greece) 20080101

• Therapeutic efficacy of curcumin/TRAIL combination regimen for hormone-refractory prostate cancer.

  Oncology research 20080101

• A simple 2-directional high-performance thin-layer chromatographic method for the simultaneous determination of curcumin, metanil yellow, and sudan dyes in turmeric, chili, and curry powders.

  Journal of AOAC International 20080101

• Inhibition of progression of erythroleukemia induced by Friend virus in BALB/c mice by natural products--berberine, curcumin and picroliv.

  Journal of experimental therapeutics & oncology 20080101

• Antimutagenic efficacy of some natural compounds on cyclophosphamide-induced p53 alterations.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20080101

• In vitro synthesis of curcuminoids by type III polyketide synthase from Oryza sativa.

  The Journal of biological chemistry 20071228

• Curcumin prevents streptozotocin-induced islet damage by scavenging free radicals: a prophylactic and protective role.

  European journal of pharmacology 20071222

• Acceleration of oxidative protein folding by curcumin through novel non-redox chemistry.

  Biochemical and biophysical research communications 20071221

• Synthesis of monofunctional curcumin derivatives, clicked curcumin dimer, and a PAMAM dendrimer curcumin conjugate for therapeutic applications.

  Organic letters 20071220

• In vivo growth inhibitory and anti-angiogenic effects of synthetic novel dienone cyclopropoxy curcumin analogs on mouse Ehrlich ascites tumor.

  Bioorganic & medicinal chemistry 20071215

• Anti-inflammatory effect of curcumin involves downregulation of MMP-9 in blood mononuclear cells.

  International immunopharmacology 20071215

• MIF tautomerase inhibitor potency of alpha,beta-unsaturated cyclic ketones.

  International immunopharmacology 20071215

• Effect of curcumin on inflammation and oxidative stress in cisplatin-induced experimental nephrotoxicity.

  Journal of agricultural and food chemistry 20071212

• Curcumin attenuates diabetic encephalopathy in rats: behavioral and biochemical evidences.

  European journal of pharmacology 20071208

• Delayed activation of PKCdelta and NFkappaB and higher radioprotection in splenic lymphocytes by copper (II)-Curcumin (1:1) complex as compared to curcumin.

  Journal of cellular biochemistry 20071201

• Curcumin suppressed anti-apoptotic signals and activated cysteine proteases for apoptosis in human malignant glioblastoma U87MG cells.

  Neurochemical research 20071201

• Curcumin induces G2/M cell cycle arrest in a p53-dependent manner and upregulates ING4 expression in human glioma.

  Journal of neuro-oncology 20071201

• IFN-gamma amplifies NFkappaB-dependent Neisseria meningitidis invasion of epithelial cells via specific upregulation of CEA-related cell adhesion molecule 1.

  Cellular microbiology 20071201

• The effect of curcumin on ethanol induced changes in suprachiasmatic nucleus (SCN) and pineal.

  Cellular and molecular neurobiology 20071201

• Targeting NOX, INOS and COX-2 in inflammatory cells: chemoprevention using food phytochemicals.

  International journal of cancer 20071201

• Copper-induced peroxidation of phosphatidylserine-containing liposomes is inhibited by nanomolar concentrations of specific antioxidants.

  Chemistry and physics of lipids 20071201

• Curcumin, both histone deacetylase and p300/CBP-specific inhibitor, represses the activity of nuclear factor kappa B and Notch 1 in Raji cells.

  Basic & clinical pharmacology & toxicology 20071201

• Curcumin effects on blood lipid profile in a 6-month human study.

  Pharmacological research 20071201

• Hypolipidemic and antioxidant effects of dietary curcumin and capsaicin in induced hypercholesterolemic rats.

  Lipids 20071201

• The role of haem oxygenase-1 in the decrease of endothelial intercellular adhesion molecule-1 expression by curcumin.

  Basic & clinical pharmacology & toxicology 20071201

• Human glutathione S-transferase-mediated glutathione conjugation of curcumin and efflux of these conjugates in Caco-2 cells.

  Chemical research in toxicology 20071201

• Influence of tetrahydrocurcumin on tail tendon collagen contents and its properties in rats with streptozotocin-nicotinamide-induced type 2 diabetes.

  Fundamental & clinical pharmacology 20071201

• Curcumin reduces burn progression in rats.

  Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 20071201

• Effect of turmeric and curcumin on oxidative stress and antioxidant enzymes in streptozotocin-induced diabetic rat.

  Medical science monitor : international medical journal of experimental and clinical research 20071201

• Curcumin induces high levels of topoisomerase I- and II-DNA complexes in K562 leukemia cells.

  Journal of natural products 20071201

• [Relationship between copper injury and apoptosis and the effect of curcumin on copper-injured BRL cells].

  Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20071201

• Linkage of curcumin-induced cell cycle arrest and apoptosis by cyclin-dependent kinase inhibitor p21(/WAF1/CIP1).

  Cell cycle (Georgetown, Tex.) 20071201

• Neuroprotective effect of curcumin is mainly mediated by blockade of microglial cell activation.

  Die Pharmazie 20071201

• [Advances in study of genus Curcuma].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20071201

• Protective role of curcumin in myocardial oxidative damage induced by isoproterenol in rats.

  Human & experimental toxicology 20071201

• The potential role of natural agents in treatment of airway inflammation.

  Therapeutic advances in respiratory disease 20071201

• Design and development of water-soluble curcumin conjugates as potential anticancer agents.

  Journal of medicinal chemistry 20071129

• Screening of the antioxidative properties and total phenolic contents of three endemic Tanacetum subspecies from Turkish flora.

  Bioresource technology 20071101

• Curcumin prevents the development of dextran sulfate Sodium (DSS)-induced experimental colitis.

  Digestive diseases and sciences 20071101

• Keratinocyte proliferation, differentiation, and apoptosis--differential mechanisms of regulation by curcumin, EGCG and apigenin.

  Toxicology and applied pharmacology 20071101

• Comparison of stratum corneum penetration and localization of a lipophilic model drug applied in an o/w microemulsion and an amphiphilic cream.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20071101

• Hepatotoxicity related to paraquat and diquat absorption through intact skin.

  Digestive diseases and sciences 20071101

• Purification and characterization of UDP-glucose : curcumin glucoside 1,6-glucosyltransferase from Catharanthus roseus cell suspension cultures.

  Plant & cell physiology 20071101

• Extended treatment with physiologic concentrations of dietary phytochemicals results in altered gene expression, reduced growth, and apoptosis of cancer cells.

  Molecular cancer therapeutics 20071101

• Solubility of core materials in aqueous polymeric solution effect on microencapsulation of curcumin.

  Drug development and industrial pharmacy 20071101

• Herbs and spices. A dash of good health.

  Mayo Clinic health letter (English ed.) 20071101

• [The study of therapeutic effects of curcumin on hepatic fibrosis and variation of correlated cytokine].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20071101

• Design, synthesis, and cytostatic activity of novel cyclic curcumin analogues.

  Bioorganic & medicinal chemistry letters 20071015

• Curcumin suppresses the transformation of an aryl hydrocarbon receptor through its phosphorylation.

  Archives of biochemistry and biophysics 20071015

• Curcumin for chemoprevention of colon cancer.

  Cancer letters 20071008

• Curcuminoids-cellular uptake by human primary colon cancer cells as quantitated by a sensitive HPLC assay and its relation with the inhibition of proliferation and apoptosis.

  Journal of agricultural and food chemistry 20071003

• The effects of tetrahydrocurcumin and green tea polyphenol on the survival of male C57BL/6 mice.

  Biogerontology 20071001

• Pharmacological doses of dietary curcumin increase colon epithelial cell proliferation in vivo in rats.

  Phytotherapy research : PTR 20071001

• MD-2 as the target of curcumin in the inhibition of response to LPS.

  Journal of leukocyte biology 20071001

• Influence of tetrahydrocurcumin on hepatic and renal functional markers and protein levels in experimental type 2 diabetic rats.

  Basic & clinical pharmacology & toxicology 20071001

• Curcumin attenuates the release of pro-inflammatory cytokines in lipopolysaccharide-stimulated BV2 microglia.

  Acta pharmacologica Sinica 20071001

• Curcumin downregulates the constitutive activity of NF-kappaB and induces apoptosis in novel mouse melanoma cells.

  Melanoma research 20071001

• Modifying effects of dietary factors on (-)-epigallocatechin-3-gallate-induced pro-matrix metalloproteinase-7 production in HT-29 human colorectal cancer cells.

  Bioscience, biotechnology, and biochemistry 20071001

• [Therapeutic effects of curcumin treatment on hepatic fibrosis].

  Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20071001

• Rapid and drastic induction of CYP3A4 mRNA expression via vitamin D receptor in human intestinal LS180 cells.

  Drug metabolism and pharmacokinetics 20071001

• [Inhibition of curcumin on histone deacetylase and expression promotion of P21 (WAF1/CIP1) in HepG2 cells].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20071001

• Influence of tetrahydrocurcumin on erythrocyte membrane bound enzymes and antioxidant status in experimental type 2 diabetic rats.

  Journal of ethnopharmacology 20070925

• Effect of curcumin on hyperglycemia-induced vascular endothelial growth factor expression in streptozotocin-induced diabetic rat retina.

  Biochemical and biophysical research communications 20070921

• Curcumin induces apoptosis through mitochondrial hyperpolarization and mtDNA damage in human hepatoma G2 cells.

  Free radical biology & medicine 20070915

• Curcumin is a modulator of bilayer material properties.

  Biochemistry 20070911

• From exotic spice to modern drug?

  Cell 20070907

• Molecular understanding and modern application of traditional medicines: triumphs and trials.

  Cell 20070907

• Standardization and stability studies of neuroprotective lipid soluble fraction obtained from Curcuma longa.

  Journal of pharmaceutical and biomedical analysis 20070903

• In vitro studies of platelet adhesion, activation, and protein adsorption on curcumin-eluting biodegradable stent materials.

  Journal of biomedical materials research. Part A 20070901

• The ubiquitin- and proteasome-dependent degradation of COX-2 is regulated by the COP9 signalosome and differentially influenced by coxibs.

  Journal of molecular medicine (Berlin, Germany) 20070901

• IGF-I plus E2 induces proliferation via activation of ROS-dependent ERKs and JNKs in human breast carcinoma cells.

  Journal of cellular physiology 20070901

• Dietary curcumin does not protect kidney in glycerol-induced acute renal failure.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20070901

• Regulation of heme oxygenase-1 expression by demethoxy curcuminoids through Nrf2 by a PI3-kinase/Akt-mediated pathway in mouse beta-cells.

  American journal of physiology. Endocrinology and metabolism 20070901

• Improved blood compatibility of rapamycin-eluting stent by incorporating curcumin.

  Colloids and surfaces. B, Biointerfaces 20070901

• Isolation and identification of phase 1 metabolites of demethoxycurcumin in rats.

  Drug metabolism and disposition: the biological fate of chemicals 20070901

• Curcumin down-regulates Ets-1 and Bcl-2 expression in human endometrial carcinoma HEC-1-A cells.

  Gynecologic oncology 20070901

• The antitumor activities of curcumin and of its isoxazole analogue are not affected by multiple gene expression changes in an MDR model of the MCF-7 breast cancer cell line: analysis of the possible molecular basis.

  International journal of molecular medicine 20070901

• Curcumin induces apoptosis and inhibits prostaglandin E(2) production in synovial fibroblasts of patients with rheumatoid arthritis.

  International journal of molecular medicine 20070901

• Oral curcumin mitigates the clinical and neuropathologic phenotype of the Trembler-J mouse: a potential therapy for inherited neuropathy.

  American journal of human genetics 20070901

• Structure-activity relationships of amyloid beta-aggregation inhibitors based on curcumin: influence of linker length and flexibility.

  Chemical biology & drug design 20070901

• Predicting the physiological relevance of in vitro cancer preventive activities of phytochemicals.

  Acta pharmacologica Sinica 20070901

• Effects of manganese complexes of curcumin and diacetylcurcumin on kainic acid-induced neurotoxic responses in the rat hippocampus.

  Biological & pharmaceutical bulletin 20070901

• Synthesis of (R)-curcumene and (R)-xanthorrizol based on 1,2-Aryl migration via phenonium ion.

  Chemical & pharmaceutical bulletin 20070901

• Curcumin augments gemcitabine cytotoxic effect on pancreatic adenocarcinoma cell lines.

  Cancer investigation 20070901

• Effect of curcumin on intracerebroventricular colchicine-induced cognitive impairment and oxidative stress in rats.

  Journal of medicinal food 20070901

• Herbal mixtures consisting of puerarin and either polyenylphosphatidylcholine or curcumin provide comprehensive protection against alcohol-related disorders in P rats receiving free choice water and 15% ethanol in pure water.

  Journal of medicinal food 20070901

• Curcumin contributes to in vitro removal of non-transferrin bound iron by deferiprone and desferrioxamine in thalassemic plasma.

  Medicinal chemistry (Shariqah (United Arab Emirates)) 20070901

• Curcumin modulation of IFN-beta and IL-12 signalling and cytokine induction in human T cells.

  Journal of cellular and molecular medicine 20070901

• Targeted inhibition of glucuronidation markedly improves drug efficacy in mice - a model.

  Biochemical and biophysical research communications 20070817

• Up-regulation of aldose reductase expression mediated by phosphatidylinositol 3-kinase/Akt and Nrf2 is involved in the protective effect of curcumin against oxidative damage.

  Free radical biology & medicine 20070815

• Role of pro-oxidants and antioxidants in the anti-inflammatory and apoptotic effects of curcumin (diferuloylmethane).

  Free radical biology & medicine 20070815

• Curcumin reverses impaired hippocampal neurogenesis and increases serotonin receptor 1A mRNA and brain-derived neurotrophic factor expression in chronically stressed rats.

  Brain research 20070808

• CXCR4 expression during tumour cell death.

  Leukemia research 20070801

• Low concentrations of curcumin induce growth arrest and apoptosis in skin keratinocytes only in combination with UVA or visible light.

  The Journal of investigative dermatology 20070801

• The redox chemistry of the Alzheimer's disease amyloid beta peptide.

  Biochimica et biophysica acta 20070801

• Curcumin labels amyloid pathology in vivo, disrupts existing plaques, and partially restores distorted neurites in an Alzheimer mouse model.

  Journal of neurochemistry 20070801

• Curcumin, demethoxycurcumin, bisdemethoxycurcumin, tetrahydrocurcumin and turmerones differentially regulate anti-inflammatory and anti-proliferative responses through a ROS-independent mechanism.

  Carcinogenesis 20070801

• Studies on the in vitro absorption of spice principles--curcumin, capsaicin and piperine in rat intestines.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20070801

• De novo synthesis of glutathione is a prerequisite for curcumin to inhibit hepatic stellate cell (HSC) activation.

  Free radical biology & medicine 20070801

• A randomized, placebo-controlled, double-blind clinical trial of curcuminoids in oral lichen planus.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20070801

• Glucuronidation of curcuminoids by human microsomal and recombinant UDP-glucuronosyltransferases.

  Molecular nutrition & food research 20070801

• A potential role for the vanilloid receptor TRPV1 in the therapeutic effect of curcumin in dinitrobenzene sulphonic acid-induced colitis in mice.

  Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20070801

• [Effect of curcumin on expression of survivin, Bcl-2 and Bax in human multiple myeloma cell line].

  Zhongguo shi yan xue ye xue za zhi 20070801

• Improving the solubility and pharmacological efficacy of curcumin by heat treatment.

  Assay and drug development technologies 20070801

• [Antimicrobial activity and constituents in rumput roman extract as a natural food preservative].

  Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20070801

• [Curcumin attenuated the lipid peroxidation and apoptotic liver injury in copper-overloaded rats].

  Zhonghua er ke za zhi = Chinese journal of pediatrics 20070801

• Interaction between curcumin and opioid system in the formalin test of rats.

  Pakistan journal of biological sciences : PJBS 20070801

• Molecular interactions between dimethoxycurcumin and Pamam dendrimer carriers.

  International journal of pharmaceutics 20070718

• Theoretical study on physicochemical properties of curcumin.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20070701

• Comparison of systemic availability of curcumin with that of curcumin formulated with phosphatidylcholine.

  Cancer chemotherapy and pharmacology 20070701

• Comparison of oxaliplatin- and curcumin-mediated antiproliferative effects in colorectal cell lines.

  International journal of cancer 20070701

• SAHA induces apoptosis in hepatoma cells and synergistically interacts with the proteasome inhibitor Bortezomib.

  Apoptosis : an international journal on programmed cell death 20070701

• Evidence that curcumin suppresses the growth of malignant gliomas in vitro and in vivo through induction of autophagy: role of Akt and extracellular signal-regulated kinase signaling pathways.

  Molecular pharmacology 20070701

• PfGCN5-mediated histone H3 acetylation plays a key role in gene expression in Plasmodium falciparum.

  Eukaryotic cell 20070701

• The relaxant effect of curcumin on porcine coronary arterial ring segments.

  Vascular pharmacology 20070701

• Unexpected effect of concomitantly administered curcumin on the pharmacokinetics of talinolol in healthy Chinese volunteers.

  European journal of clinical pharmacology 20070701

• Curcumin and cyclopalladated complexes: a recipe for bifunctional biomaterials.

  Journal of inorganic biochemistry 20070701

• Curcumin reverses breast tumor exosomes mediated immune suppression of NK cell tumor cytotoxicity.

  Biochimica et biophysica acta 20070701

• Curcumin decreases acid sphingomyelinase activity in colon cancer Caco-2 cells.

  Planta medica 20070701

• Curcumin suppresses growth and chemoresistance of human glioblastoma cells via AP-1 and NFkappaB transcription factors.

  Journal of neurochemistry 20070701

• Curcumin affects development of zebrafish embryo.

  Biological & pharmaceutical bulletin 20070701

• Antimutagenic potential of curcumin on chromosomal aberrations in Allium cepa.

  Journal of Zhejiang University. Science. B 20070701

• New cyclodextrin bioconjugates for active tumour targeting.

  Journal of drug targeting 20070701

• Heme oxygenase vs. nitric oxide synthase in signaling mediating sildenafil citrate action.

  The journal of sexual medicine 20070701

• Development and in vitro evaluation of surface modified poly(lactide-co-glycolide) nanoparticles with chitosan-4-thiobutylamidine.

  Drug development and industrial pharmacy 20070701

• Curcumin attenuates inflammatory responses of TNF-alpha-stimulated human endothelial cells.

  Journal of cardiovascular pharmacology 20070701

• A Mechanistic Approach for Modulation of Arsenic Toxicity in Human Lymphocytes by Curcumin, an Active Constituent of Medicinal Herb Curcuma longa Linn.

  Journal of clinical biochemistry and nutrition 20070701

• Roles of heme oxygenase-1 in curcumin-induced growth inhibition in rat smooth muscle cells.

  Experimental & molecular medicine 20070630

• Studies on curcumin and curcuminoids XXXI. Symmetric and asymmetric curcuminoids: stability, activity and complexation with cyclodextrin.

  International journal of pharmaceutics 20070629

• Curcumin inhibits the formation of capillary-like tubes by rat lymphatic endothelial cells.

  Cancer letters 20070628

• Oral bioavailability of curcumin in rat and the herbal analysis from Curcuma longa by LC-MS/MS.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070615

• Curcumin-induced genotoxicity and antigenotoxicity in HepG2 cells.

  Toxicon : official journal of the International Society on Toxinology 20070615

• Effects of curcumin in treatment of experimental pulmonary fibrosis: a comparison with hydrocortisone.

  Journal of ethnopharmacology 20070613

• A single amino acid in the PSPG-box plays an important role in the catalytic function of CaUGT2 (Curcumin glucosyltransferase), a Group D Family 1 glucosyltransferase from Catharanthus roseus.

  FEBS letters 20070612

• Possible inhibitory mechanism of Curcuma drugs on CYP3A4 in 1alpha,25 dihydroxyvitamin D3 treated Caco-2 cells.

  International journal of pharmaceutics 20070607

• Formulation and characterization of curcuminoids loaded solid lipid nanoparticles.

  International journal of pharmaceutics 20070607

• Inhibition of human recombinant cytochrome P450s by curcumin and curcumin decomposition products.

  Toxicology 20070603

• Investigation of the interaction between curcumin and nucleic acids in the presence of CTAB.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20070601

• Chemopreventive anti-inflammatory activities of curcumin and other phytochemicals mediated by MAP kinase phosphatase-5 in prostate cells.

  Carcinogenesis 20070601

• Bax and Bak genes are essential for maximum apoptotic response by curcumin, a polyphenolic compound and cancer chemopreventive agent derived from turmeric, Curcuma longa.

  Carcinogenesis 20070601

• Curcumin effects on inflammation and performance recovery following eccentric exercise-induced muscle damage.

  American journal of physiology. Regulatory, integrative and comparative physiology 20070601

• Curcumin induces electrical activity in rat pancreatic beta-cells by activating the volume-regulated anion channel.

  Biochemical pharmacology 20070601

• Curcumin protects against acute liver damage in the rat by inhibiting NF-kappaB, proinflammatory cytokines production and oxidative stress.

  Biochimica et biophysica acta 20070601

• Curcumin prevents tumor-induced T cell apoptosis through Stat-5a-mediated Bcl-2 induction.

  The Journal of biological chemistry 20070601

• Natural products as a gold mine for arthritis treatment.

  Current opinion in pharmacology 20070601

• A curcumin-based 1-week triple therapy for eradication of Helicobacter pylori infection: something to learn from failure?

  Helicobacter 20070601

• Analysis of the signal transduction pathway of nickel-induced matrix metalloproteinase-2 expression in the human keratinocytes in vitro: preliminary findings.

  Journal of cutaneous pathology 20070601

• New sesquiterpenes and calebin derivatives from Curcuma longa.

  Chemical & pharmaceutical bulletin 20070601

• Curcumin inhibits tumor growth and angiogenesis in ovarian carcinoma by targeting the nuclear factor-kappaB pathway.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20070601

• The study of human skin irritation of a novel herbal skin care product and ingredients by human single closed patch testing.

  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20070601

• Novel methoxylated flavone inhibitors of cytochrome P450 1B1 in SCC-9 human oral cancer cells.

  The Journal of pharmacy and pharmacology 20070601

• Inhibitory effect of curcumin on proliferation of human pterygium fibroblasts.

  Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20070601

• Tetrahydrocurcumin prevents brain lipid peroxidation in streptozotocin-induced diabetic rats.

  Journal of medicinal food 20070601

• Hypolipidemic and antioxidant effects of curcumin and capsaicin in high-fat-fed rats.

  Canadian journal of physiology and pharmacology 20070601

• Vasoactive intestinal peptide induces cyclooxygenase-2 expression through nuclear factor-kappaB in human prostate cell lines Differential time-dependent responses in cancer progression.

  Molecular and cellular endocrinology 20070530

• An efficient chemoenzymatic production of small molecule glucosides with in situ UDP-glucose recycling.

  FEBS letters 20070529

• The potentiation of curcumin on insulin-like growth factor-1 action in MCF-7 human breast carcinoma cells.

  Life sciences 20070516

• Curcumin-induced GADD153 upregulation: modulation by glutathione.

  Journal of cellular biochemistry 20070515

• Curcumin activates human glutathione S-transferase P1 expression through antioxidant response element.

  Toxicology letters 20070515

• The characterization of the sol-gel encapsulated curcumin as a possible sensor for small biologically important molecules.

  Cellular and molecular biology (Noisy-le-Grand, France) 20070515

• Effects of curcumin on peroxisome proliferator-activated receptor gamma expression and nuclear translocation/redistribution in culture-activated rat hepatic stellate cells.

  Chinese medical journal 20070505

• The Fanconi anemia (FA) pathway confers glioma resistance to DNA alkylating agents.

  Journal of molecular medicine (Berlin, Germany) 20070501

• Curcumin [1,7-bis(4-hydroxy-3-methoxyphenyl)-1-6-heptadine-3,5-dione; C21H20O6] sensitizes human prostate cancer cells to tumor necrosis factor-related apoptosis-inducing ligand/Apo2L-induced apoptosis by suppressing nuclear factor-kappaB via inhibition of the prosurvival Akt signaling pathway.

  The Journal of pharmacology and experimental therapeutics 20070501

• Suppression of NF-kappaB activation by curcumin leads to inhibition of expression of cyclo-oxygenase-2 and matrix metalloproteinase-9 in human articular chondrocytes: Implications for the treatment of osteoarthritis.

  Biochemical pharmacology 20070501

• High-performance liquid chromatography analysis of curcumin in rat plasma: application to pharmacokinetics of polymeric micellar formulation of curcumin.

  Biomedical chromatography : BMC 20070501

• The interruption of the PDGF and EGF signaling pathways by curcumin stimulates gene expression of PPARgamma in rat activated hepatic stellate cell in vitro.

  Laboratory investigation; a journal of technical methods and pathology 20070501

• Effect of curcumin and curcumin copper complex (1:1) on radiation-induced changes of anti-oxidant enzymes levels in the livers of Swiss albino mice.

  Journal of radiation research 20070501

• Curcumin for maintenance therapy in ulcerative colitis.

  Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20070501

• Microbial metabolism. Part 7 : Curcumin.

  Natural product research 20070501

• [Effect of curcumin on activity of matrix metalloproteinase 2, 9 and nuclear expression of RelA in rat hepatic stellate cells by activating peroxisome proliferator-activated receptor gamma signal].

  Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20070501

• [Study on effect of different extracts in curcuma long on stability of curcumin].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070501

• [The relationship between the effects of curcumin on cerebral ischemia/reperfusion injury and immediately genic expressions of fos, Jun and NF-kappaB in hippocampal CA1 area and its significance in gerbils].

  Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20070501

• Neuroprotective effect of curcumin on focal cerebral ischemic rats by preventing blood-brain barrier damage.

  European journal of pharmacology 20070430

• Curcumin reduces cold storage-induced damage in human cardiac myoblasts.

  Experimental & molecular medicine 20070430

• Cinnamoyl compounds as simple molecules that inhibit p300 histone acetyltransferase.

  Journal of medicinal chemistry 20070419

• Telomerase targeted anticancer bioactive prodrug by antisense-based approach.

  Cancer letters 20070418

• Curcumin potentiates antitumor activity of gemcitabine in an orthotopic model of pancreatic cancer through suppression of proliferation, angiogenesis, and inhibition of nuclear factor-kappaB-regulated gene products.

  Cancer research 20070415

• Protective effect of curcumin against liver warm ischemia/reperfusion injury in rat model is associated with regulation of heat shock protein and antioxidant enzymes.

  World journal of gastroenterology 20070407

• Curcumin attenuates the kainic acid-induced hippocampal cell death in the mice.

  Neuroscience letters 20070406

• Phytochemicals induce breast cancer resistance protein in Caco-2 cells and enhance the transport of benzo[a]pyrene-3-sulfate.

  Toxicological sciences : an official journal of the Society of Toxicology 20070401

• Curcumin attenuates glutamate-induced HT22 cell death by suppressing MAP kinase signaling.

  Molecular and cellular biochemistry 20070401

• Curcumin enhances Apo2L/TRAIL-induced apoptosis in chemoresistant ovarian cancer cells.

  Gynecologic oncology 20070401

• Amyloglucosidase-catalyzed synthesis of eugenyl and curcuminyl glycosides.

  Biotechnology letters 20070401

• Curcumin induces the degradation of cyclin E expression through ubiquitin-dependent pathway and up-regulates cyclin-dependent kinase inhibitors p21 and p27 in multiple human tumor cell lines.

  Biochemical pharmacology 20070401

• Comparative study of copper(II)-curcumin complexes as superoxide dismutase mimics and free radical scavengers.

  European journal of medicinal chemistry 20070401

• Involvement of Bcl-2 family members, phosphatidylinositol 3'-kinase/AKT and mitochondrial p53 in curcumin (diferulolylmethane)-induced apoptosis in prostate cancer.

  International journal of oncology 20070401

• Deleterious effect of nitric oxide inhibition in chronic hepatopulmonary syndrome.

  European journal of gastroenterology & hepatology 20070401

• Prevention of liver cirrhosis in rats by curcumin.

  Liver international : official journal of the International Association for the Study of the Liver 20070401

• IL-1beta causes an increase in intestinal epithelial tight junction permeability.

  Journal of immunology (Baltimore, Md. : 1950) 20070401

• Liposomal curcumin with and without oxaliplatin: effects on cell growth, apoptosis, and angiogenesis in colorectal cancer.

  Molecular cancer therapeutics 20070401

• In vitro assessment of curcumin against murine neuroblastoma cells.

  Neuro endocrinology letters 20070401

• Suppression of ochratoxin biosynthesis by naturally occurring alkaloids.

  Food additives and contaminants 20070401

• Hormetic prevention of molecular damage during cellular aging of human skin fibroblasts and keratinocytes.

  Annals of the New York Academy of Sciences 20070401

• Effect of curcumin on the induction of glutathione S-transferases and NADP(H):quinone oxidoreductase and its possible mechanism of action.

  Yao xue xue bao = Acta pharmaceutica Sinica 20070401

• Curcumin/turmeric solubilized in sodium hydroxide inhibits HNE protein modification--an in vitro study.

  Journal of ethnopharmacology 20070321

• Chalcone inhibits the activation of NF-kappaB and STAT3 in endothelial cells via endogenous electrophile.

  Life sciences 20070320

• Curcumin suppresses AP1 transcription factor-dependent differentiation and activates apoptosis in human epidermal keratinocytes.

  The Journal of biological chemistry 20070302

• Identification of kaempferol as an inhibitor of cigarette smoke-induced activation of the aryl hydrocarbon receptor and cell transformation.

  Carcinogenesis 20070301

• Curcumin-induced apoptosis in human leukemia cell HL-60 is associated with inhibition of telomerase activity.

  Molecular and cellular biochemistry 20070301

• Curcumin prevents lipopolysaccharide-induced atrogin-1/MAFbx upregulation and muscle mass loss.

  Journal of cellular biochemistry 20070301

• Mitochondrial complex I inhibition in Parkinson's disease: how can curcumin protect mitochondria?

  Antioxidants & redox signaling 20070301

• Effect of insulin and its combination with resveratrol or curcumin in attenuation of diabetic neuropathic pain: participation of nitric oxide and TNF-alpha.

  Phytotherapy research : PTR 20070301

• Changes in glycoprotein components in streptozotocin--nicotinamide induced type 2 diabetes: influence of tetrahydrocurcumin from Curcuma longa.

  Plant foods for human nutrition (Dordrecht, Netherlands) 20070301

• Curcumin-induced degradation of ErbB2: A role for the E3 ubiquitin ligase CHIP and the Michael reaction acceptor activity of curcumin.

  Biochimica et biophysica acta 20070301

• Photosensitizer effect of curcumin on UVB-irradiated HaCaT cells through activation of caspase pathways.

  Oncology reports 20070301

• Curcumin attenuates the expression of IL-1beta, IL-6, and TNF-alpha as well as cyclin E in TNF-alpha-treated HaCaT cells; NF-kappaB and MAPKs as potential upstream targets.

  International journal of molecular medicine 20070301

• Curcumin, a Curcuma longa constituent, acts on MAPK p38 pathway modulating COX-2 and iNOS expression in chronic experimental colitis.

  International immunopharmacology 20070301

• Curcumin downregulates homeobox gene NKX3.1 in prostate cancer cell LNCaP.

  Acta pharmacologica Sinica 20070301

• Curcumin, a dietary component, has anticancer, chemosensitization, and radiosensitization effects by down-regulating the MDM2 oncogene through the PI3K/mTOR/ETS2 pathway.

  Cancer research 20070301

• ASC-J9 ameliorates spinal and bulbar muscular atrophy phenotype via degradation of androgen receptor.

  Nature medicine 20070301

• Curcumin potentiates the apoptotic effects of chemotherapeutic agents and cytokines through down-regulation of nuclear factor-kappaB and nuclear factor-kappaB-regulated gene products in IFN-alpha-sensitive and IFN-alpha-resistant human bladder cancer cells.

  Molecular cancer therapeutics 20070301

• Efficacy of curcumin therapy against Angiostrongylus cantonensis-induced eosinophilic meningitis.

  Journal of helminthology 20070301

• Moderate coffee drinking may have many benefits.

  The Journal of the Michigan Dental Association 20070301

• [The effect of curcumin on bleomycin-induced pulmonary fibrosis in rats].

  Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20070301

• Curcumin induces pro-apoptotic endoplasmic reticulum stress in human leukemia HL-60 cells.

  Biochemical and biophysical research communications 20070223

• NCB-02 (standardized Curcumin preparation) protects dinitrochlorobenzene- induced colitis through down-regulation of NFkappa-B and iNOS.

  World journal of gastroenterology 20070221

• Curcumin opens cystic fibrosis transmembrane conductance regulator channels by a novel mechanism that requires neither ATP binding nor dimerization of the nucleotide-binding domains.

  The Journal of biological chemistry 20070216

• Metabolism and anticancer activity of the curcumin analogue, dimethoxycurcumin.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20070215

• Curcumin enhances cystic fibrosis transmembrane regulator expression by down-regulating calreticulin.

  Biochemical and biophysical research communications 20070209

• Curcumin-phospholipid complex: Preparation, therapeutic evaluation and pharmacokinetic study in rats.

  International journal of pharmaceutics 20070207

• Curcuminoids, curcumin, and demethoxycurcumin reduce lead-induced memory deficits in male Wistar rats.

  Journal of agricultural and food chemistry 20070207

• Curcumin induces changes in expression of genes involved in cholesterol homeostasis.

  The Journal of nutritional biochemistry 20070201

• Increased expression of the MGMT repair protein mediated by cysteine prodrugs and chemopreventative natural products in human lymphocytes and tumor cell lines.

  Carcinogenesis 20070201

• Modulation of function of three ABC drug transporters, P-glycoprotein (ABCB1), mitoxantrone resistance protein (ABCG2) and multidrug resistance protein 1 (ABCC1) by tetrahydrocurcumin, a major metabolite of curcumin.

  Molecular and cellular biochemistry 20070201

• The inhibition of human glutathione S-transferases activity by plant polyphenolic compounds ellagic acid and curcumin.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20070201

• Synthesis and characterization of new beta-diketo derivatives with iron chelating ability.

  Journal of inorganic biochemistry 20070201

• Dietary polyphenolic phytochemicals--promising cancer chemopreventive agents in humans? A review of their clinical properties.

  International journal of cancer 20070201

• Modulation of pregnane X receptor- and electrophile responsive element-mediated gene expression by dietary polyphenolic compounds.

  Free radical biology & medicine 20070201

• Curcumin induces G2/M arrest and apoptosis in cisplatin-resistant human ovarian cancer cells by modulating Akt and p38 MAPK.

  Cancer biology & therapy 20070201

• Comparative effects of curcumin and its synthetic analogue on tissue lipid peroxidation and antioxidant status during nicotine-induced toxicity.

  Singapore medical journal 20070201

• Small molecule inhibitors of Stat3 signaling pathway.

  Current cancer drug targets 20070201

• NMR study of the solution structure of curcumin.

  Journal of natural products 20070201

• Spice Healer.

  Scientific American 20070201

• [Comparison of preparing two polylactide nanoparticles loaded lipophilic anti-cancer herb drug by nanoprecipitation method].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070201

• Curcuminoids form reactive glucuronides in vitro.

  Journal of agricultural and food chemistry 20070124

• Quantitative determination of eight components in rhizome (Jianghuang) and tuberous root (Yujin) of Curcuma longa using pressurized liquid extraction and gas chromatography-mass spectrometry.

  Journal of pharmaceutical and biomedical analysis 20070117

• Inhibitory activity of stilbenes on Alzheimer's beta-amyloid fibrils in vitro.

  Bioorganic & medicinal chemistry 20070115

• Determination of curcumin by its quenching effect on the fluorescence of Eu3+-tryptophan complex.

  Journal of pharmaceutical and biomedical analysis 20070104

• Preclinical assessment of curcumin as a potential therapy for B-CLL.

  American journal of hematology 20070101

• Disruption of transforming growth factor-beta signaling by curcumin induces gene expression of peroxisome proliferator-activated receptor-gamma in rat hepatic stellate cells.

  American journal of physiology. Gastrointestinal and liver physiology 20070101

• A two generation reproductive toxicity study with curcumin, turmeric yellow, in Wistar rats.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20070101

• c-Abl kinase regulates curcumin-induced cell death through activation of c-Jun N-terminal kinase.

  Molecular pharmacology 20070101

• Impact of curcumin-induced changes in P-glycoprotein and CYP3A expression on the pharmacokinetics of peroral celiprolol and midazolam in rats.

  Drug metabolism and disposition: the biological fate of chemicals 20070101

• The interference of rosmarinic acid in the DNA fragmentation induced by osmotic shock.

  Frontiers in bioscience : a journal and virtual library 20070101

• Curcumin induces heme oxygenase 1 through generation of reactive oxygen species, p38 activation and phosphatase inhibition.

  International journal of molecular medicine 20070101

• Modulation of protein kinase C by curcumin; inhibition and activation switched by calcium ions.

  British journal of pharmacology 20070101

• Cis-parinaric acid effects, cytotoxicity, c-Jun N-terminal protein kinase, forkhead transcription factor and Mn-SOD differentially in malignant and normal astrocytes.

  Neurochemical research 20070101

• Resveratrol and curcumin suppress immune response through CD28/CTLA-4 and CD80 co-stimulatory pathway.

  Clinical and experimental immunology 20070101

• Spleen tyrosine kinase (Syk), a novel target of curcumin, is required for B lymphoma growth.

  Journal of immunology (Baltimore, Md. : 1950) 20070101

• Curcumin synergistically augments bcr/abl phosphorothioate antisense oligonucleotides to inhibit growth of chronic myelogenous leukemia cells.

  Acta pharmacologica Sinica 20070101

• Effect of azoxymethane and curcumin on transcriptional levels of cyclooxygenase-1 and -2 during initiation of colon carcinogenesis.

  Scandinavian journal of gastroenterology 20070101

• Gene-expression profiling during curcumin-induced apoptosis reveals downregulation of CXCR4.

  Experimental hematology 20070101

• Pharmacological targeting of lysine acetyltransferases in human disease: a progress report.

  Drug discovery today 20070101

• Comparative antioxidant activities of curcumin and its demethoxy and hydrogenated derivatives.

  Biological & pharmaceutical bulletin 20070101

• Synthesis of novel curcumin analogues and their evaluation as selective cyclooxygenase-1 (COX-1) inhibitors.

  Chemical & pharmaceutical bulletin 20070101

• Tumor-induced oxidative stress perturbs nuclear factor-kappaB activity-augmenting tumor necrosis factor-alpha-mediated T-cell death: protection by curcumin.

  Cancer research 20070101

• 'Spicing up' of the immune system by curcumin.

  Journal of clinical immunology 20070101

• Curcumin and kolaviron ameliorate di-n-butylphthalate-induced testicular damage in rats.

  Basic & clinical pharmacology & toxicology 20070101

• Anti-cancer activities of pure curry feeding in cancer cell-transplanted mouse.

  Asia Pacific journal of clinical nutrition 20070101

• Potential usefulness of curcumin in cystic fibrosis.

  Medical hypotheses 20070101

• The chemopreventive polyphenol Curcumin prevents hematogenous breast cancer metastases in immunodeficient mice.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20070101

• Curcumin induced suicidal erythrocyte death.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20070101

• Selection of reliable reference genes for qPCR studies on chondroprotective action.

  BMC molecular biology 20070101

• Possible neuroprotective mechanisms of curcumin in attenuating 3-nitropropionic acid-induced neurotoxicity.

  Methods and findings in experimental and clinical pharmacology 20070101

• Curcumin reduces indomethacin-induced damage in the rat small intestine.

  Journal of applied toxicology : JAT 20070101

• Comparative cytotoxicity and ROS generation by curcumin and tetrahydrocurcumin following visible-light irradiation or treatment with horseradish peroxidase.

  Anticancer research 20070101

• UVB-induced IL-18 production in human keratinocyte cell line NCTC 2544 through NF-kappaB activation.

  Cytokine 20070101

• Antineoplastic and anticlastogenic properties of curcumin.

  Annals of the New York Academy of Sciences 20070101

• Effect of curcumin treatment on protein phosphorylation in K562 cells.

  Annals of the New York Academy of Sciences 20070101

• Antioxidative effects of plant polyphenols: from protection of G protein signaling to prevention of age-related pathologies.

  Annals of the New York Academy of Sciences 20070101

• Predicting the biological activities of 2-methoxyphenol antioxidants: effects of dimers.

  In vivo (Athens, Greece) 20070101

• Review. Facts and fiction of phytotherapy for prostate cancer: a critical assessment of preclinical and clinical data.

  In vivo (Athens, Greece) 20070101

• HPLC-photodiode array detection analysis of curcuminoids in Curcuma species indigenous to Indonesia.

  Phytochemical analysis : PCA 20070101

• Sensitivity of bladder cancer cells to curcumin and its derivatives depends on the extracellular matrix.

  Anticancer research 20070101

• Analysis of the in vitro metabolites of diferuloylmethane (curcumin) by liquid chromatography--tandem mass spectrometry on a hybrid quadrupole linear ion trap system: newly identified metabolites.

  European journal of drug metabolism and pharmacokinetics 20070101

• Protective effect of curcumin and chlorophyllin against DNA mutation induced by cyclophosphamide or benzo[a]pyrene.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20070101

• Curcumin: the Indian solid gold.

  Advances in experimental medicine and biology 20070101

• Highly active anticancer curcumin analogues.

  Advances in experimental medicine and biology 20070101

• Antioxidant and anti-inflammatory properties of curcumin.

  Advances in experimental medicine and biology 20070101

• Modulation of transcription factors by curcumin.

  Advances in experimental medicine and biology 20070101

• Cancer chemopreventive effects of curcumin.

  Advances in experimental medicine and biology 20070101

• Antitumor, anti-invasion, and antimetastatic effects of curcumin.

  Advances in experimental medicine and biology 20070101

• Curcumin as an inhibitor of angiogenesis.

  Advances in experimental medicine and biology 20070101

• Neuroprotective effects of curcumin.

  Advances in experimental medicine and biology 20070101

• Regulation of COX and LOX by curcumin.

  Advances in experimental medicine and biology 20070101

• Molecular targets of curcumin.

  Advances in experimental medicine and biology 20070101

• Cell growth regulation.

  Advances in experimental medicine and biology 20070101

• Curcumin as chemosensitizer.

  Advances in experimental medicine and biology 20070101

• Radioprotection and radiosensitization by curcumin.

  Advances in experimental medicine and biology 20070101

• Immunomodulation by curcumin.

  Advances in experimental medicine and biology 20070101

• Beneficial role of curcumin in skin diseases.

  Advances in experimental medicine and biology 20070101

• Cardioprotective effects of curcumin.

  Advances in experimental medicine and biology 20070101

• Protection from acute and chronic lung diseases by curcumin.

  Advances in experimental medicine and biology 20070101

• Nephroprotective and hepatoprotective effects of curcuminoids.

  Advances in experimental medicine and biology 20070101

• Curcumin and autoimmune disease.

  Advances in experimental medicine and biology 20070101

• Pharmacokinetics and pharmacodynamics of curcumin.

  Advances in experimental medicine and biology 20070101

• Clinical studies with curcumin.

  Advances in experimental medicine and biology 20070101

• Curcumin derivatives inhibit or modulate beta-amyloid precursor protein metabolism.

  Neuro-degenerative diseases 20070101

• Pretreatment of curcumin attenuates coagulopathy and renal injury in LPS-induced endotoxemia.

  Journal of endotoxin research 20070101

• Role of curcumin in cancer therapy.

  Current problems in cancer 20070101

• Control of the growth of human breast cancer cells in culture by manipulation of arachidonate metabolism.

  BMC cancer 20070101

• Aflatoxin induced hemolysis and its amelioration by turmeric extracts and curcumin in vitro.

  Acta poloniae pharmaceutica 20070101

• Curcumin (1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione) blocks the chemotaxis of neutrophils by inhibiting signal transduction through IL-8 receptors.

  Mediators of inflammation 20070101

• Roles of the Akt/mTOR/p70S6K and ERK1/2 signaling pathways in curcumin-induced autophagy.

  Autophagy 20070101

• Antihyperlipidemic effect of curcumin and tetrahydrocurcumin in experimental type 2 diabetic rats.

  Renal failure 20070101

• Protective in vivo effect of curcumin on copper genotoxicity evaluated by comet and micronucleus assays.

  Journal of applied genetics 20070101

• Bioavailability of curcumin: problems and promises.

  Molecular pharmaceutics 20070101

• Putative cancer chemopreventive agents of dietary origin-how safe are they?

  Nutrition and cancer 20070101

• Radiation-induced incidence of thymic lymphoma in mice and its prevention by antioxidants.

  Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20070101

• Comparative radical-scavenging activity of curcumin and tetrahydrocurcumin with thiols as measured by the induction period method.

  In vivo (Athens, Greece) 20070101

• Ameliorative effect of curcumin on aflatoxin-induced toxicity in DNA, RNA and protein in liver and kidney of mice.

  Acta poloniae pharmaceutica 20070101

• Curcumin ameliorates aflatoxin-induced lipid peroxidation in liver, kidney and testis of mice--an in vitro study.

  Acta poloniae pharmaceutica 20070101

• Tumor necrosis factor alpha alters Na+-K+ ATPase activity in rat cardiac myocytes: involvement of NF-kappaB, AP-1 and PGE2.

  Life sciences 20061214

• Metabolic profiling of turmeric (Curcuma longa L.) plants derived from in vitro micropropagation and conventional greenhouse cultivation.

  Journal of agricultural and food chemistry 20061213

• Distinct mechanisms underlie distinct polyphenol-induced neuroprotection.

  FEBS letters 20061211

• Protective effect of curcumin on gamma-radiation induced DNA damage and lipid peroxidation in cultured human lymphocytes.

  Mutation research 20061210

• Dietary antioxidant curcumin inhibits microtubule assembly through tubulin binding.

  The FEBS journal 20061201

• Curcumin maintenance therapy for ulcerative colitis: randomized, multicenter, double-blind, placebo-controlled trial.

  Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20061201

• Contact urticaria from curcumin.

  Dermatitis : contact, atopic, occupational, drug 20061201

• The proteasome as a potential target for novel anticancer drugs and chemosensitizers.

  Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 20061201

• [Up-regulates the expression of maspin gene in prostate cancer cell line LNCaP].

  Yao xue xue bao = Acta pharmaceutica Sinica 20061201

• Influence of curcumin, capsaicin, and piperine on the rat liver drug-metabolizing enzyme system in vivo and in vitro.

  Canadian journal of physiology and pharmacology 20061201

• Curcumin regulates signal transducer and activator of transcription (STAT) expression in K562 cells.

  Biochemical pharmacology 20061130

• Curcumin reverses the effects of chronic stress on behavior, the HPA axis, BDNF expression and phosphorylation of CREB.

  Brain research 20061129

• Curcumin down regulates smokeless tobacco-induced NF-kappaB activation and COX-2 expression in human oral premalignant and cancer cells.

  Toxicology 20061110

• Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.

  Journal of molecular graphics & modelling 20061101

• Novel curcumin analogs targeting TNF-induced NF-kappaB activation and proliferation in human leukemic KBM-5 cells.

  Bioorganic & medicinal chemistry 20061101

• Curry consumption and cognitive function in the elderly.

  American journal of epidemiology 20061101

• Curcumin inhibits hypoxia-inducible factor-1 by degrading aryl hydrocarbon receptor nuclear translocator: a mechanism of tumor growth inhibition.

  Molecular pharmacology 20061101

• Preparation, characterization and anticoagulation of curcumin-eluting controlled biodegradable coating stents.

  Journal of controlled release : official journal of the Controlled Release Society 20061101

• Efficacy and mechanism of action of turmeric supplements in the treatment of experimental arthritis.

  Arthritis and rheumatism 20061101

• Tetrahydrocurcumin: effect on chloroquine-mediated oxidative damage in rat kidney.

  Basic & clinical pharmacology & toxicology 20061101

• Curcumin inhibits in vitro MCP-1 release from mouse pancreatic islets.

  Transplantation proceedings 20061101

• Significance of autologous interleukin-6 production in the HA22T/VGH cell model of hepatocellular carcinoma.

  Annals of the New York Academy of Sciences 20061101

• Inhibitory effect of curcumin on nitric oxide production from lipopolysaccharide-activated primary microglia.

  Life sciences 20061019

• TPA-induced up-regulation of activator protein-1 can be inhibited or enhanced by analogs of the natural product curcumin.

  Biochemical pharmacology 20061016

• Curcumin activated both receptor-mediated and mitochondria-mediated proteolytic pathways for apoptosis in human glioblastoma T98G cells.

  Neuroscience letters 20061016

• Resistance to apoptosis of HCW-2 cells can be overcome by curcumin- or vincristine-induced mitotic catastrophe.

  International journal of cancer 20061015

• Curcumin has potent liver preservation properties in an isolated perfusion model.

  Transplantation 20061015

• Curcumin and dehydrozingerone derivatives: synthesis, radiolabeling, and evaluation for beta-amyloid plaque imaging.

  Journal of medicinal chemistry 20061005

• Curcumin sensitizes tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis through CHOP-independent DR5 upregulation.

  Carcinogenesis 20061001

• Induction of early apoptosis and ROS-generation activity in human gingival fibroblasts (HGF) and human submandibular gland carcinoma (HSG) cells treated with curcumin.

  Archives of oral biology 20061001

• Curcumin improves wound healing by modulating collagen and decreasing reactive oxygen species.

  Molecular and cellular biochemistry 20061001

• Transport of liposomal and albumin loaded curcumin to living cells: an absorption and fluorescence spectroscopic study.

  Biochimica et biophysica acta 20061001

• Jak3- and JNK-dependent vascular endothelial growth factor expression in cutaneous T-cell lymphoma.

  Leukemia 20061001

• Protective effect of dietary curcumin and capsaicin on induced oxidation of low-density lipoprotein, iron-induced hepatotoxicity and carrageenan-induced inflammation in experimental rats.

  The FEBS journal 20061001

• Tetrahydracurcumin-related allergic contact dermatitis.

  Contact dermatitis 20061001

• Curcumin, the active principle of turmeric (Curcuma longa), ameliorates diabetic nephropathy in rats.

  Clinical and experimental pharmacology & physiology 20061001

• Synthesis and biological analysis of new curcumin analogues bearing an enhanced potential for the medicinal treatment of cancer.

  Molecular cancer therapeutics 20061001

• Inhibitory effect of curcumin on MDR1 gene expression in patient leukemic cells.

  Archives of pharmacal research 20061001

• Curry & onion chemicals may prevent colon cancer.

  Health news (Waltham, Mass.) 20061001

• Antioxidant effect of tetrahydrocurcumin in streptozotocin-nicotinamide induced diabetic rats.

  Life sciences 20060927

• Targeting constitutive and interleukin-6-inducible signal transducers and activators of transcription 3 pathway in head and neck squamous cell carcinoma cells by curcumin (diferuloylmethane).

  International journal of cancer 20060915

• Hydrogen peroxide-mediated downregulation of matrix metalloprotease-2 in indomethacin-induced acute gastric ulceration is blocked by melatonin and other antioxidants.

  Free radical biology & medicine 20060915

• A mechanism for coordinating chromatin modification and preinitiation complex assembly.

  Molecular cell 20060915

• Curcumin inhibits neurotensin-mediated interleukin-8 production and migration of HCT116 human colon cancer cells.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20060915

• [Curcumin-induced the expression of inhibitor kappaBalpha protein in human prostate cancer cells].

  Zhonghua wai ke za zhi [Chinese journal of surgery] 20060915

• Progressive nuclear factor-kappaB activation resistant to inhibition by contraction and curcumin in mdx mice.

  Muscle & nerve 20060901

• Modification by curcumin of mutagenic activation of carcinogenic N-nitrosamines by extrahepatic cytochromes P-450 2B1 and 2E1 in rats.

  Cancer science 20060901

• Curcumin attenuates gentamicin-induced renal oxidative damage in rats.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20060901

• Biosynthesis of curcuminoids and gingerols in turmeric (Curcuma longa) and ginger (Zingiber officinale): identification of curcuminoid synthase and hydroxycinnamoyl-CoA thioesterases.

  Phytochemistry 20060901

• Emerging role of polyphenolic compounds in the treatment of neurodegenerative diseases: a review of their intracellular targets.

  European journal of pharmacology 20060901

• Protective effects of curcumin on methylglyoxal-induced oxidative DNA damage and cell injury in human mononuclear cells.

  Acta pharmacologica Sinica 20060901

• Curcuminoids enhance amyloid-beta uptake by macrophages of Alzheimer's disease patients.

  Journal of Alzheimer's disease : JAD 20060901

• Cumulative antioxidant defense against oxidative challenge in galactose-induced cataractogenesis in Wistar rats.

  Indian journal of experimental biology 20060901

• Multiple molecular targets in cancer chemoprevention by curcumin.

  The AAPS journal 20060901

• Comparative effects of curcuminoids on endothelial heme oxygenase-1 expression: ortho-methoxy groups are essential to enhance heme oxygenase activity and protection.

  Experimental & molecular medicine 20060831

• Effects of capsaicin, dihydrocapsaicin, and curcumin on copper-induced oxidation of human serum lipids.

  Journal of agricultural and food chemistry 20060823

• Curcumin abolishes apoptosis resistance of calcitriol-differentiated HL-60 cells.

  FEBS letters 20060821

• Curcumin inhibits the mammalian target of rapamycin-mediated signaling pathways in cancer cells.

  International journal of cancer 20060815

• Comparative study of natural antioxidants - curcumin, resveratrol and melatonin - in cadmium-induced oxidative damage in mice.

  Toxicology 20060815

• Curcumin mediates ceramide generation via the de novo pathway in colon cancer cells.

  Carcinogenesis 20060801

• Dosage effects of curcumin on cell death types in a human osteoblast cell line.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20060801

• Curcumin combats against cigarette smoke and ethanol-induced lipid alterations in rat lung and liver.

  Molecular and cellular biochemistry 20060801

• Combination treatment with curcumin and quercetin of adenomas in familial adenomatous polyposis.

  Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20060801

• Curcumin inhibits trinitrobenzene sulphonic acid-induced colitis in rats by activation of peroxisome proliferator-activated receptor gamma.

  International immunopharmacology 20060801

• House dust mite allergen Der p 1 elevates the release of inflammatory cytokines and expression of adhesion molecules in co-culture of human eosinophils and bronchial epithelial cells.

  International immunology 20060801

• Curcumin inhibits telomerase activity in human cancer cell lines.

  International journal of molecular medicine 20060801

• Suppression of hepatocyte CYP1A2 expression by Kupffer cells via AhR pathway: the central role of proinflammatory cytokines.

  International journal of molecular medicine 20060801

• Curcumin regulated shift from Th1 to Th2 in trinitrobenzene sulphonic acid-induced chronic colitis.

  Acta pharmacologica Sinica 20060801

• Inhibition of oxidative stress and cytokine activity by curcumin in amelioration of endotoxin-induced experimental hepatoxicity in rodents.

  Clinical and experimental immunology 20060801

• Effect of tetrahydrocurcumin on lipid peroxidation and lipids in streptozotocin-nicotinamide-induced diabetic rats.

  Basic & clinical pharmacology & toxicology 20060801

• Modulation of the function of the multidrug resistance-linked ATP-binding cassette transporter ABCG2 by the cancer chemopreventive agent curcumin.

  Molecular cancer therapeutics 20060801

• Solubility and stability of curcumin in solutions containing alginate and other viscosity modifying macromolecules. Studies of curcumin and curcuminoids. XXX.

  Die Pharmazie 20060801

• Trichostatin A improves the anticancer activity of low concentrations of curcumin in human leukemia cells.

  Die Pharmazie 20060801

• [Apoptosis in nasopharyngeal carcinoma cell line NCE induced by curcumin and its molecular mechanism].

  Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery 20060801

• [Effect of curcumin on pulmonary hypertension and wall collagen of pulmonary arterioles of chronic hypoxic hypercapnic rats].

  Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20060801

• Beneficial influence of dietary curcumin, capsaicin and garlic on erythrocyte integrity in high-fat fed rats.

  The Journal of nutritional biochemistry 20060701

• The anti-inflammatory effect of curcumin in an experimental model of sepsis is mediated by up-regulation of peroxisome proliferator-activated receptor-gamma.

  Critical care medicine 20060701

• Curcumin protects against radiation-induced acute and chronic cutaneous toxicity in mice and decreases mRNA expression of inflammatory and fibrogenic cytokines.

  International journal of radiation oncology, biology, physics 20060701

• Effect of curcumin on protein glycosylation, lipid peroxidation, and oxygen radical generation in human red blood cells exposed to high glucose levels.

  Free radical biology & medicine 20060701

• The spice of life: curcumin reduces the mortality associated with experimental sepsis.

  Critical care medicine 20060701

• Curcumin decreases binding of Shiga-like toxin-1B on human intestinal epithelial cell line HT29 stimulated with TNF-alpha and IL-1beta: suppression of p38, JNK and NF-kappaB p65 as potential targets.

  Biological & pharmaceutical bulletin 20060701

• Turmeric and curcumin modulate the conjugation of 1-naphthol in Caco-2 cells.

  Biological & pharmaceutical bulletin 20060701

• Curcumin affects components of the chromosomal passenger complex and induces mitotic catastrophe in apoptosis-resistant Bcr-Abl-expressing cells.

  Molecular cancer research : MCR 20060701

• A specific method for measurement of equine active myeloperoxidase in biological samples and in in vitro tests.

  Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc 20060701

• [Study on the chemical constituents of Curcuma phaeocaulis].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20060701

• [Apoptosis of lens epithelial cell induced by curcumin and its mechanism].

  [Zhonghua yan ke za zhi] Chinese journal of ophthalmology 20060701

• Antitumor agents. 250. Design and synthesis of new curcumin analogues as potential anti-prostate cancer agents.

  Journal of medicinal chemistry 20060629

• Inhibition of homodimerization of Toll-like receptor 4 by curcumin.

  Biochemical pharmacology 20060628

• Curcumin-attenuated trinitrobenzene sulphonic acid induces chronic colitis by inhibiting expression of cyclooxygenase-2.

  World journal of gastroenterology 20060628

• Silencing of the human microsomal glucose-6-phosphate translocase induces glioma cell death: potential new anticancer target for curcumin.

  FEBS letters 20060626

• Curcumin potently blocks Kv1.4 potassium channels.

  Biochemical and biophysical research communications 20060616

• Overexpression of p65/RelA potentiates curcumin-induced apoptosis in HCT116 human colon cancer cells.

  Carcinogenesis 20060601

• Mitochondrial and nuclear DNA damage induced by curcumin in human hepatoma G2 cells.

  Toxicological sciences : an official journal of the Society of Toxicology 20060601

• Curcumin protects PC12 cells against 1-methyl-4-phenylpyridinium ion-induced apoptosis by bcl-2-mitochondria-ROS-iNOS pathway.

  Apoptosis : an international journal on programmed cell death 20060601

• Notch-1 down-regulation by curcumin is associated with the inhibition of cell growth and the induction of apoptosis in pancreatic cancer cells.

  Cancer 20060601

• Pharmacological rescue of carnitine transport in primary carnitine deficiency.

  Human mutation 20060601

• Interferon-alpha resistance can be reversed by inhibition of IFN-alpha-induced COX-2 expression potentially via STAT1 activation in A549 cells.

  Oncology reports 20060601

• Curcumin inhibits hypoxia-induced angiogenesis via down-regulation of HIF-1.

  Oncology reports 20060601

• Synthesis of EF24-tripeptide chloromethyl ketone: a novel curcumin-related anticancer drug delivery system.

  Journal of medicinal chemistry 20060601

• Down-regulation of p210(bcr/abl) by curcumin involves disrupting molecular chaperone functions of Hsp90.

  Acta pharmacologica Sinica 20060601

• Antimicrobials, mucosal coating agents, anesthetics, analgesics, and nutritional supplements for alimentary tract mucositis.

  Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20060601

• Growth inhibition and apoptosis inducing mechanisms of curcumin on human ovarian cancer cell line A2780.

  Chinese journal of integrative medicine 20060601

• Molecular orbital basis for yellow curry spice curcumin's prevention of Alzheimer's disease.

  Journal of agricultural and food chemistry 20060517

• Curcumin suppresses the expression of extracellular matrix genes in activated hepatic stellate cells by inhibiting gene expression of connective tissue growth factor.

  American journal of physiology. Gastrointestinal and liver physiology 20060501

• Rescue of DeltaF508-CFTR (cystic fibrosis transmembrane conductance regulator) by curcumin: involvement of the keratin 18 network.

  The Journal of pharmacology and experimental therapeutics 20060501

• Antitumor action of curcumin in human papillomavirus associated cells involves downregulation of viral oncogenes, prevention of NFkB and AP-1 translocation, and modulation of apoptosis.

  Molecular carcinogenesis 20060501

• Fluorescence enhancement of the protein-curcumin-sodium dodecyl benzene sulfonate system and protein determination.

  Analytical and bioanalytical chemistry 20060501

• Curcumin attenuates thermal hyperalgesia in a diabetic mouse model of neuropathic pain.

  European journal of pharmacology 20060501

• Induction of G2/M arrest and inhibition of cyclooxygenase-2 activity by curcumin in human bladder cancer T24 cells.

  Oncology reports 20060501

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• Effect of curcumin on proliferation of human retinal endothelial cells under in vitro conditions.

  Investigative ophthalmology & visual science 20060501

• Cytotoxic effect of curcumin on Giardia lamblia trophozoites.

  Acta tropica 20060501

• [Effect of curcumin on acetylation of histone H3 in human lymphoma cell line Raji].

  Ai zheng = Aizheng = Chinese journal of cancer 20060501

• Biological effects of curcumin and its role in cancer chemoprevention and therapy.

  Anti-cancer agents in medicinal chemistry 20060501

• Synthetic curcuminoids modulate the arachidonic acid metabolism of human platelet 12-lipoxygenase and reduce sprout formation of human endothelial cells.

  Molecular cancer therapeutics 20060501

• [Prophylactic effect of curcumin on hepatic fibrosis and its relationship with activated hepatic stellate cells].

  Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20060501

• Immediate and delayed treatments with curcumin prevents forebrain ischemia-induced neuronal damage and oxidative insult in the rat hippocampus.

  Neurochemical research 20060501

• Oral administration of diferuloylmethane (curcumin) suppresses proinflammatory cytokines and destructive connective tissue remodeling in experimental abdominal aortic aneurysms.

  Annals of vascular surgery 20060501

• Curcumin's biphasic hormetic response on proteasome activity and heat-shock protein synthesis in human keratinocytes.

  Annals of the New York Academy of Sciences 20060501

• Effect of curcumin on the expression of LDL receptor in mouse macrophages.

  Journal of ethnopharmacology 20060421

• Curcumin enhances the polyglutamine-expanded truncated N-terminal huntingtin-induced cell death by promoting proteasomal malfunction.

  Biochemical and biophysical research communications 20060421

• Antitumor agents 247. New 4-ethoxycarbonylethyl curcumin analogs as potential antiandrogenic agents.

  Bioorganic & medicinal chemistry 20060415

• Indomethacin inactivates gastric peroxidase to induce reactive-oxygen-mediated gastric mucosal injury and curcumin protects it by preventing peroxidase inactivation and scavenging reactive oxygen.

  Free radical biology & medicine 20060415

• Curcumin modulates drug metabolizing enzymes in the female Swiss Webster mouse.

  Life sciences 20060411

• Inhibition of telomerase activity and induction of apoptosis by curcumin in K-562 cells.

  Mutation research 20060411

• Use of liquid chromatography-electrospray ionization tandem mass spectrometry to identify diarylheptanoids in turmeric (Curcuma longa L.) rhizome.

  Journal of chromatography. A 20060407

• Selective protection of curcumin against carbon tetrachloride-induced inactivation of hepatic cytochrome P450 isozymes in rats.

  Life sciences 20060404

• Transcriptional regulation of VCAM-1 expression by tumor necrosis factor-alpha in human tracheal smooth muscle cells: involvement of MAPKs, NF-kappaB, p300, and histone acetylation.

  Journal of cellular physiology 20060401

• Curcumin blocks activation of pancreatic stellate cells.

  Journal of cellular biochemistry 20060401

• Activation of NFkappaB is inhibited by curcumin and related enones.

  Bioorganic & medicinal chemistry 20060401

• Iron chelation in the biological activity of curcumin.

  Free radical biology & medicine 20060401

• Potential synergism of natural products in the treatment of cancer.

  Phytotherapy research : PTR 20060401

• Cellular foundation of curcumin-induced apoptosis in follicular lymphoma cell lines.

  Experimental hematology 20060401

• Discovery of new small molecules and targets towards angiogenesis via chemical genomics approach.

  Current drug targets 20060401

• Curcumin targets Akt cell survival signaling pathway in HTLV-I-infected T-cell lines.

  Cancer science 20060401

• [Regulatory effect of curcumin on p300 and HDAC1 in B-NHL cells].

  Zhongguo shi yan xue ye xue za zhi 20060401

• Curcumin-induced histone hypoacetylation enhances caspase-3-dependent glioma cell death and neurogenesis of neural progenitor cells.

  Stem cells and development 20060401

• Curcumin induces caspase-3-dependent apoptotic pathway but inhibits DNA fragmentation factor 40/caspase-activated DNase endonuclease in human Jurkat cells.

  Molecular cancer therapeutics 20060401

• Chemosensitization to cisplatin by inhibitors of the Fanconi anemia/BRCA pathway.

  Molecular cancer therapeutics 20060401

• [Experimental study on protective effects of curcumin on exaggerated extracellular matrix accumulation of pulmonary fibrosis rats].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060401

• Neuroprotective and anti-ageing effects of curcumin in aged rat brain regions.

  Biogerontology 20060401

• The antioxidants curcumin and quercetin inhibit inflammatory processes associated with arthritis.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20060401

• [Experimental study on effect of curcumin on inhibiting injury of free radical in pulmonary fibrosis rats].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060401

• [The study on reversing mechanism of multidrug resistance of K562/A02 cell line by curcumin and erythromycin].

  Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20060401

• Multiple biological activities of curcumin: a short review.

  Life sciences 20060327

• Role of protein kinase C delta in curcumin-induced antioxidant response element-mediated gene expression in human monocytes.

  Biochemical and biophysical research communications 20060324

• Curcumin inhibits the proliferation and mineralization of cultured osteoblasts.

  European journal of pharmacology 20060318

• The effects of the phenylalanine 256 to valine mutation on the sensitivity of sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA) Ca2+ pump isoforms 1, 2, and 3 to thapsigargin and other inhibitors.

  The Journal of biological chemistry 20060317

• Interleukin-18 induces the production of vascular endothelial growth factor (VEGF) in rheumatoid arthritis synovial fibroblasts via AP-1-dependent pathways.

  Immunology letters 20060315

• Prevention of kainic acid-induced changes in nitric oxide level and neuronal cell damage in the rat hippocampus by manganese complexes of curcumin and diacetylcurcumin.

  Life sciences 20060313

• Curcumin suppresses constitutive activation of AP-1 by downregulation of JunD protein in HTLV-1-infected T-cell lines.

  Leukemia research 20060301

• SERCA pump inhibitors do not correct biosynthetic arrest of deltaF508 CFTR in cystic fibrosis.

  American journal of respiratory cell and molecular biology 20060301

• Inhibition of EGFR signaling in human prostate cancer PC-3 cells by combination treatment with beta-phenylethyl isothiocyanate and curcumin.

  Carcinogenesis 20060301

• Involvement of Nrf2, p38, B-Raf, and nuclear factor-kappaB, but not phosphatidylinositol 3-kinase, in induction of hemeoxygenase-1 by dietary polyphenols.

  Molecular pharmacology 20060301

• Antiproliferation and apoptosis induced by curcumin in human ovarian cancer cells.

  Cell biology international 20060301

• CFTR is required for PKA-regulated ATP sensitivity of Kir1.1 potassium channels in mouse kidney.

  The Journal of clinical investigation 20060301

• Molecular mechanism of tumor necrosis factor-alpha modulation of intestinal epithelial tight junction barrier.

  American journal of physiology. Gastrointestinal and liver physiology 20060301

• Effects of administration of Embelin and Curcumin on lipid peroxidation, hepatic glutathione antioxidant defense and hematopoietic system during N-nitrosodiethylamine/Phenobarbital-induced hepatocarcinogenesis in Wistar rats.

  Molecular and cellular biochemistry 20060301

• Structural relationship of curcumin derivatives binding to the BRCT domain of human DNA polymerase lambda.

  Genes to cells : devoted to molecular & cellular mechanisms 20060301

• Curcumin inhibits WT1 gene expression in human leukemic K562 cells.

  Acta pharmacologica Sinica 20060301

• Apoptosis-inducing effects of curcumin derivatives in human bladder cancer cells.

  Anti-cancer drugs 20060301

• Curcumin analogs as potent aldose reductase inhibitors.

  Archiv der Pharmazie 20060301

• Inhibitory effect of cinnamoyl compounds against human malignant cell line.

  Indian journal of experimental biology 20060301

• Histone modifications in kainate-induced status epilepticus.

  The European journal of neuroscience 20060301

• Turmeric extracts containing curcuminoids prevent experimental rheumatoid arthritis.

  Journal of natural products 20060301

• Microemulsion electrokinetic chromatography for separation and analysis of curcuminoids in turmeric samples.

  Journal of separation science 20060301

• [Effects of Zhikeping on aortic oxyradical and the expression of ICAM-1 in a rat model of experimental early atherosclerosis].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060301

• [Effect of three different curcumin pigmens on the prdiferation of vascular smooth muscle cells by ox-LDL and the expression of LDL-R].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060301

• Curcumin is an inhibitor of p300 histone acetylatransferase.

  Medicinal chemistry (Shariqah (United Arab Emirates)) 20060301

• Amyloid-beta peptide binds with heme to form a peroxidase: relationship to the cytopathologies of Alzheimer's disease.

  Proceedings of the National Academy of Sciences of the United States of America 20060227

• Curcumin induces heme oxygenase-1 in hepatocytes and is protective in simulated cold preservation and warm reperfusion injury.

  Transplantation 20060227

• Validated LC/MS/MS assay for curcumin and tetrahydrocurcumin in rat plasma and application to pharmacokinetic study of phospholipid complex of curcumin.

  Journal of pharmaceutical and biomedical analysis 20060224

• The human transcription factor AP-1 is a mediator of bile acid-induced liver cell apoptosis.

  Biochemical and biophysical research communications 20060217

• Curcumin induces growth-arrest and apoptosis in association with the inhibition of constitutively active JAK-STAT pathway in T cell leukemia.

  Biochemical and biophysical research communications 20060210

• Metabolism of curcuminoids in tissue slices and subcellular fractions from rat liver.

  Journal of agricultural and food chemistry 20060208

• Curcuminoids purified from turmeric powder modulate the function of human multidrug resistance protein 1 (ABCC1).

  Cancer chemotherapy and pharmacology 20060201

• Curcumin (diferuloylmethane) inhibits constitutive active NF-kappaB, leading to suppression of cell growth of human T-cell leukemia virus type I-infected T-cell lines and primary adult T-cell leukemia cells.

  International journal of cancer 20060201

• Piceatannol upregulates endothelial heme oxygenase-1 expression via novel protein kinase C and tyrosine kinase pathways.

  Pharmacological research 20060201

• Curcumin synergistically potentiates the growth-inhibitory and pro-apoptotic effects of celecoxib in osteoarthritis synovial adherent cells.

  Rheumatology (Oxford, England) 20060201

• Dietary curcumin counteracts the outcome of traumatic brain injury on oxidative stress, synaptic plasticity, and cognition.

  Experimental neurology 20060201

• Alpha-glucosidase inhibition of natural curcuminoids and curcumin analogs.

  European journal of medicinal chemistry 20060201

• Cyclooxygenase-2 expression and oxidative DNA adducts in murine intestinal adenomas: modification by dietary curcumin and implications for clinical trials.

  European journal of cancer (Oxford, England : 1990) 20060201

• Opposing action of curcumin and green tea polyphenol in human keratinocytes.

  Molecular nutrition & food research 20060201

• Effects of curcumin on tumour necrosis factor-alpha and interleukin-6 in the late phase of experimental acute pancreatitis.

  Journal of veterinary medicine. A, Physiology, pathology, clinical medicine 20060201

• Curcumin and its analogues as potent inhibitors of low density lipoprotein oxidation: H-atom abstraction from the phenolic groups and possible involvement of the 4-hydroxy-3-methoxyphenyl groups.

  Free radical biology & medicine 20060201

• Attenuation of renal fibrosis by curcumin in rat obstructive nephropathy.

  Urology 20060201

• Curcumin induces apoptosis via inhibition of PI3'-kinase/AKT pathway in acute T cell leukemias.

  Apoptosis : an international journal on programmed cell death 20060201

• Curcumin ameliorates acute thioacetamide-induced hepatotoxicity.

  Journal of gastroenterology and hepatology 20060201

• [Curcumin-induced apoptosis in androgen-dependent prostate cancer cell line LNCaP in vitro].

  Zhonghua nan ke xue = National journal of andrology 20060201

• Induced resistance in the human non small cell lung carcinoma (NCI-H460) cell line in vitro by anticancer drugs.

  Journal of chemotherapy (Florence, Italy) 20060201

• [Inhibitory effect of curcumin on angiogenesis induced by brain derived neurotrophic factor from multiple myeloma cells].

  Zhongguo shi yan xue ye xue za zhi 20060201

• Alisol B acetate, a triterpene from Alismatis rhizoma, induces Bax nuclear translocation and apoptosis in human hormone-resistant prostate cancer PC-3 cells.

  Cancer letters 20060118

• Combined inhibitory effects of curcumin and phenethyl isothiocyanate on the growth of human PC-3 prostate xenografts in immunodeficient mice.

  Cancer research 20060115

• Curcumin inhibits human colon cancer cell growth by suppressing gene expression of epidermal growth factor receptor through reducing the activity of the transcription factor Egr-1.

  Oncogene 20060112

• Aminopeptidase-N/CD13 (EC 3.4.11.2) inhibitors: chemistry, biological evaluations, and therapeutic prospects.

  Medicinal research reviews 20060101

• Curcumin (diferuloylmethane) down-regulates expression of cell proliferation and antiapoptotic and metastatic gene products through suppression of IkappaBalpha kinase and Akt activation.

  Molecular pharmacology 20060101

• Inhibition of lipid peroxidation and protein oxidation in rat liver mitochondria by curcumin and its analogues.

  Biochimica et biophysica acta 20060101

• Curcumin inhibits platelet-derived growth factor-stimulated vascular smooth muscle cell function and injury-induced neointima formation.

  Arteriosclerosis, thrombosis, and vascular biology 20060101

• Cutaneous distribution and localization of dyes affected by vehicles all with different lipophilicity.

  Archives of dermatological research 20060101

• The role of nuclear factor-kappa B in bacterial translocation in cholestatic rats.

  Pediatric surgery international 20060101

• Synergistic inhibitory effects of curcumin and 5-fluorouracil on the growth of the human colon cancer cell line HT-29.

  Chemotherapy 20060101

• The influence of curcumin and manganese complex of curcumin on cadmium-induced oxidative damage and trace elements status in tissues of mice.

  Journal of applied toxicology : JAT 20060101

• Curcumin, an atoxic antioxidant and natural NFkappaB, cyclooxygenase-2, lipooxygenase, and inducible nitric oxide synthase inhibitor: a shield against acute and chronic diseases.

  JPEN. Journal of parenteral and enteral nutrition 20060101

• Of spices and fruits and wine.

  JPEN. Journal of parenteral and enteral nutrition 20060101

• The effects of curcumin on the invasiveness of prostate cancer in vitro and in vivo.

  Prostate cancer and prostatic diseases 20060101

• [Signal transduction mechanism of curcumin in inhibiting the proliferation of bovine lens epithelial cell induced by recombinant human epidermal growth factor].

  Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20060101

• Modulation of nuclear factor E2-related factor 2-mediated gene expression in mice liver and small intestine by cancer chemopreventive agent curcumin.

  Molecular cancer therapeutics 20060101

• The sensitive fluorimetric method for the determination of curcumin using the enhancement of mixed micelle.

  Journal of fluorescence 20060101

• Anti- and pro-oxidant effects of oxidized quercetin, curcumin or curcumin-related compounds with thiols or ascorbate as measured by the induction period method.

  In vivo (Athens, Greece) 20060101

• A combined strategy to reduce restenosis for vascular tissue engineering applications.

  Biotechnology progress 20060101

• Curcumin induces stress response, neurite outgrowth and prevent NF-kappaB activation by inhibiting the proteasome function.

  Neurotoxicity research 20060101

• [Human pregnane X receptor-mediated transcriptional regulation of cytochrome P450 3A4 by some phytochemicals].

  Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20060101

• Analysis of curcuminoids by positive and negative electrospray ionization and tandem mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20060101

• Turmeric (curcumin): a widely used curry ingredient, can contribute to oxidative stress in Asian patients with acute vitiligo.

  Indian journal of dermatology, venereology and leprology 20060101

• Spice it up: disease-fighting flavors.

  Consumer reports 20060101

• Inhibitory effect of curcumin on WT1 gene expression in patient leukemic cells.

  Archives of pharmacal research 20060101

• Modest induction of phase 2 enzyme activity in the F-344 rat prostate.

  BMC cancer 20060101

• Effects of curcumin on tumor angiogenesis and biomarkers, COX-2 and VEGF, in hepatocellular carcinoma cell-implanted nude mice.

  Clinical hemorheology and microcirculation 20060101

• Dose escalation of a curcuminoid formulation.

  BMC complementary and alternative medicine 20060101

• Photodynamic effect of curcumin on NPC/CNE2 cells.

  Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20060101

• Curcumin inhibits cell migration of human colon cancer colo 205 cells through the inhibition of nuclear factor kappa B /p65 and down-regulates cyclooxygenase-2 and matrix metalloproteinase-2 expressions.

  Anticancer research 20060101

• Curcumin activates defensive genes and protects neurons against oxidative stress.

  Antioxidants & redox signaling 20060101

• Prevention of 1,2-dimethylhydrazine-induced circulatory oxidative stress by bis-1,7-(2-hydroxyphenyl)-hepta-1,6-diene-3,5-dione during colon carcinogenesis.

  Pharmacological reports : PR 20060101

• Down-regulation of prostaglandin E2 by curcumin is correlated with inhibition of cell growth and induction of apoptosis in human colon carcinoma cell lines.

  Journal of the Society for Integrative Oncology 20060101

• COX-inhibitors relieve the immunosuppressive effect of tumor cells and improve functions of immune effectors.

  International journal of immunopathology and pharmacology 20060101

• HDAC1 expression and effect of curcumin on proliferation of Raji cells.

  Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20060101

• Curcumin protects mouse brain from oxidative stress caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

  European review for medical and pharmacological sciences 20060101

• Curcumin induces cell death without oligonucleosomal DNA fragmentation in quiescent and proliferating human CD8+ cells.

  Acta biochimica Polonica 20060101

• Regulation of LDL receptor expression by the effect of curcumin on sterol regulatory element pathway.

  Pharmacological reports : PR 20060101

• Curcumin content of turmeric and curry powders.

  Nutrition and cancer 20060101

• Mechanisms of curcumin- and EGF-receptor related protein (ERRP)-dependent growth inhibition of colon cancer cells.

  Nutrition and cancer 20060101

• Antimicrobial emulsion (coating) based on biopolymer containing neem (Melia azardichta) and turmeric (Curcuma longa) extract for wound covering.

  Bio-medical materials and engineering 20060101

• DNA damage in mouse lymphocytes exposed to curcumin and copper.

  Journal of applied genetics 20060101

• Biological evaluation of curcumin and related diarylheptanoids.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20060101

• Combined effects of curcumin and vitamin C to protect endothelial dysfunction in the iris tissue of STZ-induced diabetic rats.

  Clinical hemorheology and microcirculation 20060101

• The impact of diet and exercise on brain plasticity and disease.

  Nutrition and health 20060101

• Curcumin-induced cell cycle arrest and apoptosis in human acute promyelocytic leukemia HL-60 cells via MMP changes and caspase-3 activation.

  Anticancer research 20060101

• Curcumin-induced apoptosis of human colon cancer colo 205 cells through the production of ROS, Ca2+ and the activation of caspase-3.

  Anticancer research 20060101

• Celecoxib and curcumin additively inhibit the growth of colorectal cancer in a rat model.

  Digestion 20060101

• Effect of tetrahydrocurcumin on plasma antioxidants in streptozotocin-nicotinamide experimental diabetes.

  Journal of basic and clinical physiology and pharmacology 20060101

• Curcumin, a potential inhibitor of MMP-2 in human laryngeal squamous carcinoma cells HEp2.

  Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20060101

• Protective effect of curcumin on endotoxin-induced acute lung injury in rats.

  Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20060101

• Effects of TNF-alpha and curcumin on the expression of VEGF in Raji and U937 cells and on angiogenesis in ECV304 cells.

  Chinese medical journal 20051220

• Antioxidant and antiinflammatory activities of xanthorrhizol in hippocampal neurons and primary cultured microglia.

  Journal of neuroscience research 20051215

• Beneficial effects of the bioflavonoids curcumin and quercetin on early function in cadaveric renal transplantation: a randomized placebo controlled trial.

  Transplantation 20051215

• Modulation of signal transduction by tea catechins and related phytochemicals.

  Mutation research 20051211

• Hydrogen peroxide stimulates proliferation and migration of human prostate cancer cells through activation of activator protein-1 and up-regulation of the heparin affin regulatory peptide gene.

  The Journal of biological chemistry 20051209

• Monoacetylcurcumin: a new inhibitor of eukaryotic DNA polymerase lambda and a new ligand for inhibitor-affinity chromatography.

  Biochemical and biophysical research communications 20051202

• Curcumin prevents methylglyoxal-induced oxidative stress and apoptosis in mouse embryonic stem cells and blastocysts.

  Journal of cellular physiology 20051201

• Curcumin treatment protects rat retinal neurons against excitotoxicity: effect on N-methyl-D: -aspartate-induced intracellular Ca(2+) increase.

  Experimental brain research 20051201

• Synthesis and biological evaluation of polyhydroxycurcuminoids.

  Bioorganic & medicinal chemistry 20051201

• Prevention of Alzheimer's disease: Omega-3 fatty acid and phenolic anti-oxidant interventions.

  Neurobiology of aging 20051201

• Curcumin induces human HT-29 colon adenocarcinoma cell apoptosis by activating p53 and regulating apoptosis-related protein expression.

  Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20051201

• [Apoptosis induced by curcumin and its effect on c-myc and caspase-3 expressions in human melanoma A375 cell line].

  Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20051201

• Effect of curcumin on atherosclerosis in apoE/LDLR-double knockout mice.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20051201

• [Progress on the study of mechanism of the direct action of TCM bioactive components on ovarian cancer].

  Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20051201

• Curcumin is a potent broad spectrum inhibitor of matrix metalloproteinase gene expression in human astroglioma cells.

  Biochemical and biophysical research communications 20051118

• Curcuma longa L. constituents inhibit sortase A and Staphylococcus aureus cell adhesion to fibronectin.

  Journal of agricultural and food chemistry 20051116

• Inhibition of nuclear translocation of nuclear factor-kappaB despite lack of functional IkappaBalpha protein overcomes multiple defects in apoptosis signaling in human B-cell malignancies.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20051115

• Effects of naturally occurring compounds on fibril formation and oxidative stress of beta-amyloid.

  Journal of agricultural and food chemistry 20051102

• Curcumin sensitizes tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis through reactive oxygen species-mediated upregulation of death receptor 5 (DR5).

  Carcinogenesis 20051101

• Curcumin suppresses interleukin 1beta-mediated microsomal prostaglandin E synthase 1 by altering early growth response gene 1 and other signaling pathways.

  The Journal of pharmacology and experimental therapeutics 20051101

• Effect of artemisinin/artesunate as inhibitors of hepatitis B virus production in an 'in vitro' replicative system.

  Antiviral research 20051101

• Synthesis and characterization of dual function vanadyl, gallium and indium curcumin complexes for medicinal applications.

  Journal of inorganic biochemistry 20051101

• Time-dependent changes in antioxidant enzymes and vascular reactivity of aorta in streptozotocin-induced diabetic rats treated with curcumin.

  Journal of cardiovascular pharmacology 20051101

• Curcumin blocks fibrosis in anti-Thy 1 glomerulonephritis through up-regulation of heme oxygenase 1.

  Kidney international 20051101

• Curcumin therapy in inflammatory bowel disease: a pilot study.

  Digestive diseases and sciences 20051101

• Curcumin treatment abrogates endoplasmic reticulum retention and aggregation-induced apoptosis associated with neuropathy-causing myelin protein zero-truncating mutants.

  American journal of human genetics 20051101

• Use of cancer chemopreventive phytochemicals as antineoplastic agents.

  The Lancet. Oncology 20051101

• Proapoptotic effect of curcumin on human neutrophils: activation of the p38 mitogen-activated protein kinase pathway.

  Critical care medicine 20051101

• An old spice with new twists: curcumin, p38 mitogen-activated protein kinase, and apoptosis.

  Critical care medicine 20051101

• Curcumin protects human chondrocytes from IL-l1beta-induced inhibition of collagen type II and beta1-integrin expression and activation of caspase-3: an immunomorphological study.

  Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft 20051101

• Curcumin inhibits the classical and the alternate pathways of complement activation.

  Annals of the New York Academy of Sciences 20051101

• Curcumin: getting back to the roots.

  Annals of the New York Academy of Sciences 20051101

• [Recent development and future direction of anti-aging therapy by supplements].

  Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 20051101

• Curcumin suppresses growth and induces apoptosis in primary effusion lymphoma.

  Oncogene 20051027

• Curcumin suppresses the paclitaxel-induced nuclear factor-kappaB pathway in breast cancer cells and inhibits lung metastasis of human breast cancer in nude mice.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20051015

• Curcumin suppresses phorbol ester-induced matrix metalloproteinase-9 expression by inhibiting the PKC to MAPK signaling pathways in human astroglioma cells.

  Biochemical and biophysical research communications 20051007

• Neuroprotective mechanisms of curcumin against cerebral ischemia-induced neuronal apoptosis and behavioral deficits.

  Journal of neuroscience research 20051001

• The role and regulation of hepatic stellate cell apoptosis in reversal of liver fibrosis.

  Apoptosis : an international journal on programmed cell death 20051001

• Effects of nuclear factor-kappaB inhibitors and its implication on natural killer T-cell lymphoma cells.

  British journal of haematology 20051001

• Curcumin suppresses growth of head and neck squamous cell carcinoma.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20051001

• Neuroprotective properties of the natural phenolic antioxidants curcumin and naringenin but not quercetin and fisetin in a 6-OHDA model of Parkinson's disease.

  Free radical research 20051001

• A pilot study of the antioxidant effect of curcumin in tropical pancreatitis.

  The Indian journal of medical research 20051001

• [Protective effect of curcumin on myocardial ischemia reperfusion injury in rats].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20051001

• Curcumin synergistically potentiates the growth inhibitory and pro-apoptotic effects of celecoxib in pancreatic adenocarcinoma cells.

  Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20051001

• Tetrahydrocurcumin in plasma and urine: quantitation by high performance liquid chromatography.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050925

• Liposome-encapsulated curcumin: in vitro and in vivo effects on proliferation, apoptosis, signaling, and angiogenesis.

  Cancer 20050915

• Evaluation of a new copper(II)-curcumin complex as superoxide dismutase mimic and its free radical reactions.

  Free radical biology & medicine 20050915

• Celecoxib and curcumin synergistically inhibit the growth of colorectal cancer cells.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20050915

• Stability-indicating HPTLC determination of curcumin in bulk drug and pharmaceutical formulations.

  Journal of pharmaceutical and biomedical analysis 20050901

• Chemopreventive effects of embelin and curcumin against N-nitrosodiethylamine/phenobarbital-induced hepatocarcinogenesis in Wistar rats.

  Fitoterapia 20050901

• Curcumin (diferuloylmethane) inhibits constitutive NF-kappaB activation, induces G1/S arrest, suppresses proliferation, and induces apoptosis in mantle cell lymphoma.

  Biochemical pharmacology 20050901

• Study of the interaction of proteins with curcumin and SDS and its analytical application.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20050901

• Curcumin: the story so far.

  European journal of cancer (Oxford, England : 1990) 20050901

• Inhibition of survival signalling by dietary polyphenols and indole-3-carbinol.

  European journal of cancer (Oxford, England : 1990) 20050901

• Effects of SKI306X on arachidonate metabolism and other inflammatory mediators.

  Biological & pharmaceutical bulletin 20050901

• Antidepressant effects of curcumin in the forced swim test and olfactory bulbectomy models of depression in rats.

  Pharmacology, biochemistry, and behavior 20050901

• Efficiency of foam fractionation for the enrichment of nonpolar compounds from aqueous extracts of plant materials.

  Journal of natural products 20050901

• [Effect of curcumin on the gene expression of low density lipoprotein receptors].

  Chinese journal of integrative medicine 20050901

• Inhibition of cellular proliferation and induction of apoptosis by curcumin in human malignant astrocytoma cell lines.

  Journal of neuro-oncology 20050901

• Synthesis of guaiacol-alpha-D: -glucoside and curcumin-bis-alpha-D: -glucoside by an amyloglucosidase from Rhizopus.

  Biotechnology letters 20050901

• [Inhibition of the expression of prostate specific antigen by curcumin].

  Yao xue xue bao = Acta pharmaceutica Sinica 20050901

• [Effects of curcumin on the acetylation of histone H3, P53 and the proliferation of NB4 cells].

  Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20050901

• Curcumin inhibits interferon-alpha induced NF-kappaB and COX-2 in human A549 non-small cell lung cancer cells.

  Biochemical and biophysical research communications 20050826

• Synthesis of novel curcumin mimics with asymmetrical units and their anti-angiogenic activity.

  Bioorganic & medicinal chemistry letters 20050815

• The relationship between the anti-inflammatory effects of curcumin and cellular glutathione content in myelomonocytic cells.

  Biochemical pharmacology 20050815

• Curcumin-induced antiproliferative and proapoptotic effects in melanoma cells are associated with suppression of IkappaB kinase and nuclear factor kappaB activity and are independent of the B-Raf/mitogen-activated/extracellular signal-regulated protein kinase pathway and the Akt pathway.

  Cancer 20050815

• Curcumin has a palliative action on gentamicin-induced nephrotoxicity in rats.

  Fundamental & clinical pharmacology 20050801

• Effect of curcumin on multidrug resistance in resistant human gastric carcinoma cell line SGC7901/VCR.

  Acta pharmacologica Sinica 20050801

• Elucidation of anti-allergic activities of curcumin-related compounds with a special reference to their anti-oxidative activities.

  Biological & pharmaceutical bulletin 20050801

• [Chemical genomics on new angiogenesis inhibitors].

  Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 20050801

• [Effect of curcumin on caspase 8- and caspase 9- induced apoptosis of lymphoma Raji cell].

  Zhongguo shi yan xue ye xue za zhi 20050801

• Inhibition of radiation induced nitration by curcumin and nicotinamide in mouse macrophages.

  Molecular and cellular biochemistry 20050801

• C-reactive protein decreases expression of thrombomodulin and endothelial protein C receptor in human endothelial cells.

  Surgery 20050801

• Inhibition of Naja naja venom hyaluronidase by plant-derived bioactive components and polysaccharides.

  Biochemistry. Biokhimiia 20050801

• Curcumin derivatives inhibit the formation of Jun-Fos-DNA complex independently of their conserved cysteine residues.

  Journal of biochemistry and molecular biology 20050731

• Modulation of alpha-crystallin chaperone activity in diabetic rat lens by curcumin.

  Molecular vision 20050726

• The effects of curcumin on depressive-like behaviors in mice.

  European journal of pharmacology 20050725

• Combined effects of GSTP1 and MRP1 in melanoma drug resistance.

  British journal of cancer 20050725

• Resveratrol and curcumin reduce the respiratory burst of Chlamydia-primed THP-1 cells.

  Biochemical and biophysical research communications 20050722

• Active site binding modes of curcumin in HIV-1 protease and integrase.

  Bioorganic & medicinal chemistry letters 20050715

• Effect of anti-inflammatory and antioxidant drugs on the long-term repair of severely injured mouse skeletal muscle.

  Experimental physiology 20050701

• Apoptosis and age-dependant induction of nuclear and mitochondrial etheno-DNA adducts in Long-Evans Cinnamon (LEC) rats: enhanced DNA damage by dietary curcumin upon copper accumulation.

  Carcinogenesis 20050701

• Thioredoxin reductase is irreversibly modified by curcumin: a novel molecular mechanism for its anticancer activity.

  The Journal of biological chemistry 20050701

• Comparative effects of curcumin and an analogue of curcumin in carbon tetrachloride-induced hepatotoxicity in rats.

  Basic & clinical pharmacology & toxicology 20050701

• Relationship between intracellular ROS production and membrane mobility in curcumin- and tetrahydrocurcumin-treated human gingival fibroblasts and human submandibular gland carcinoma cells.

  Oral diseases 20050701

• Studies on curcumin and curcuminoids. XXIX. Photoinduced cytotoxicity of curcumin in selected aqueous preparations.

  Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20050701

• Curcumin attenuates diet-induced hypercholesterolemia in rats.

  Medical science monitor : international medical journal of experimental and clinical research 20050701

• School students as Drosophila experimenters.

  PLoS biology 20050701

• Curcumin inhibits the expression of COX-2 in UVB-irradiated human keratinocytes (HaCaT) by inhibiting activation of AP-1: p38 MAP kinase and JNK as potential upstream targets.

  Experimental & molecular medicine 20050630

• Curcumin enhances Vinorelbine mediated apoptosis in NSCLC cells by the mitochondrial pathway.

  Biochemical and biophysical research communications 20050617

• Antitumor effects of curcumin, alone or in combination with cisplatin or doxorubicin, on human hepatic cancer cells. Analysis of their possible relationship to changes in NF-kB activation levels and in IAP gene expression.

  Cancer letters 20050616

• Inhibition of multidrug resistance proteins MRP1 and MRP2 by a series of alpha,beta-unsaturated carbonyl compounds.

  Biochemical pharmacology 20050615

• Curcumin inhibits immunostimulatory function of dendritic cells: MAPKs and translocation of NF-kappa B as potential targets.

  Journal of immunology (Baltimore, Md. : 1950) 20050615

• Suppressive effects of dietary curcumin on the increased activity of renal ornithine decarboxylase in mice treated with a renal carcinogen, ferric nitrilotriacetate.

  Biochimica et biophysica acta 20050610

• Chemopreventive and therapeutic effects of curcumin.

  Cancer letters 20050608

• Antioxidant and antiproliferative activity of curcumin semicarbazone.

  Bioorganic & medicinal chemistry letters 20050602

• Synthesis and biological evaluation of aromatic enones related to curcumin.

  Bioorganic & medicinal chemistry 20050602

• Antioxidant and antigenotoxic effects of plant cell wall hydroxycinnamic acids in cultured HT-29 cells.

  Molecular nutrition & food research 20050601

• Anti-oxidant activities of curcumin and related enones.

  Bioorganic & medicinal chemistry 20050601

• Curcumin decreases cell proliferation rates through BTG2-mediated cyclin D1 down-regulation in U937 cells.

  International journal of oncology 20050601

• CSN5/Jab1 is involved in ligand-dependent degradation of estrogen receptor {alpha} by the proteasome.

  Molecular and cellular biology 20050601

• Application of capillary zone electrophoresis in the separation and determination of the curcuminoids in urine.

  Journal of pharmaceutical and biomedical analysis 20050601

• Curcumin and turmeric delay streptozotocin-induced diabetic cataract in rats.

  Investigative ophthalmology & visual science 20050601

• Curcumin blocks HIV protease inhibitor ritonavir-induced vascular dysfunction in porcine coronary arteries.

  Journal of the American College of Surgeons 20050601

• Sodium phenylbutyrate prolongs survival and regulates expression of anti-apoptotic genes in transgenic amyotrophic lateral sclerosis mice.

  Journal of neurochemistry 20050601

• Protective role of antioxidative food factors in oxidative stress caused by hyperglycemia.

  Annals of the New York Academy of Sciences 20050601

• Chemopreventive properties of curcumin.

  Future oncology (London, England) 20050601

• The inhibitory mechanism of curcumin and its derivative against beta-catenin/Tcf signaling.

  FEBS letters 20050523

• Curcumin selectively induces apoptosis in deregulated cyclin D1-expressed cells at G2 phase of cell cycle in a p53-dependent manner.

  The Journal of biological chemistry 20050520

• Differential apoptotic and redox regulatory activities of curcumin and its derivatives.

  Free radical biology & medicine 20050515

• Calcyclin (S100A6) expression is stimulated by agents evoking oxidative stress via the antioxidant response element.

  Biochimica et biophysica acta 20050515

• Increase of intracellular glutathione by low-level NO mediated by transcription factor NF-kappaB in RAW 264.7 cells.

  Biochimica et biophysica acta 20050515

• Pharmacological basis for the use of turmeric in gastrointestinal and respiratory disorders.

  Life sciences 20050513

• Curcumin modulation of Na,K-ATPase: phosphoenzyme accumulation, decreased K+ occlusion, and inhibition of hydrolytic activity.

  British journal of pharmacology 20050501

• Nutraceuticals and cancer management.

  Frontiers in bioscience : a journal and virtual library 20050501

• Plant-derived anti-inflammatory compounds affect MIF tautomerase activity.

  International immunopharmacology 20050501

• Inhibition of NFkappaB activation with curcumin attenuates plasma inflammatory cytokines surge and cardiomyocytic apoptosis following cardiac ischemia/reperfusion.

  The Journal of surgical research 20050501

• Curcumin, a potent anti-tumor reagent, is a novel histone deacetylase inhibitor regulating B-NHL cell line Raji proliferation.

  Acta pharmacologica Sinica 20050501

• Primum non nocere: does the current research publication system (or the lay press) harm our patients?

  American journal of respiratory and critical care medicine 20050501

• Free phytosterols facilitate excretion of endogenous cholesterol in gerbils.

  The Journal of nutritional biochemistry 20050501

• The anti-inflammatory compound curcumin inhibits Neisseria gonorrhoeae-induced NF-kappaB signaling, release of pro-inflammatory cytokines/chemokines and attenuates adhesion in late infection.

  Biological chemistry 20050501

• [Effect of curcumin on expression of human low density lipoprotein receptors in Xenopus Laevis oocytes].

  Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20050501

• Curcumin inhibits ROS formation and apoptosis in methylglyoxal-treated human hepatoma G2 cells.

  Annals of the New York Academy of Sciences 20050501

• [Possible candidates for the compound which is expected to attenuate dioxin toxicity].

  Fukuoka igaku zasshi = Hukuoka acta medica 20050501

• Mechanism of inhibition of ascites tumor growth in mice by curcumin is mediated by NF-kB and caspase activated DNase.

  Molecular and cellular biochemistry 20050501

• Protective role of tetrahydrocurcumin (THC) an active principle of turmeric on chloroquine induced hepatotoxicity in rats.

  Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20050430

• Bile acids induce MUC2 overexpression in human colon carcinoma cells.

  Cancer 20050415

• Curcumin-induced histone hypoacetylation: the role of reactive oxygen species.

  Biochemical pharmacology 20050415

• Phosphorylation of c-Jun N-terminal Kinases (JNKs) is involved in the preventive effect of xanthorrhizol on cisplatin-induced hepatotoxicity.

  Archives of toxicology 20050401

• Human colon cancer cells lacking Bax resist curcumin-induced apoptosis and Bax requirement is dispensable with ectopic expression of Smac or downregulation of Bcl-XL.

  Carcinogenesis 20050401

• Inhibition of NF-kappa B activation can attenuate ischemia/reperfusion-induced contractility impairment via decreasing cardiomyocytic proinflammatory gene up-regulation and matrix metalloproteinase expression.

  Journal of cardiovascular pharmacology 20050401

• Curcumin overcomes the inhibitory effect of nitric oxide on Leishmania.

  Parasitology research 20050401

• Design, synthesis, biological evaluation and molecular docking of curcumin analogues as antioxidant, cyclooxygenase inhibitory and anti-inflammatory agents.

  Bioorganic & medicinal chemistry letters 20050401

• Common spice may slow Alzheimer's.

  Health news (Waltham, Mass.) 20050401

• [The inhibitory effect of curcumin on the growth of human colon cancer cells (HT-29, WiDr) in vitro].

  The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi 20050401

• Synthesis and antitumor activity of some curcumin analogs.

  Archiv der Pharmazie 20050401

• A potential role of the curry spice curcumin in Alzheimer's disease.

  Current Alzheimer research 20050401

• Preventive and therapeutic effects of NF-kappaB inhibitor curcumin in rats colitis induced by trinitrobenzene sulfonic acid.

  World journal of gastroenterology 20050328

• Curcumin regulates expression and activity of matrix metalloproteinases 9 and 2 during prevention and healing of indomethacin-induced gastric ulcer.

  The Journal of biological chemistry 20050311

• Activation of PPAR{gamma} by curcumin inhibits Moser cell growth and mediates suppression of gene expression of cyclin D1 and EGFR.

  American journal of physiology. Gastrointestinal and liver physiology 20050301

• Constitutive activation of transcription factor AP-1 in cervical cancer and suppression of human papillomavirus (HPV) transcription and AP-1 activity in HeLa cells by curcumin.

  International journal of cancer 20050301

• Zedoariae rhizoma and curcumin inhibits platelet-derived growth factor-induced proliferation of human hepatic myofibroblasts.

  International immunopharmacology 20050301

• Mixed ligand copper(II) complexes of phenanthroline/bipyridyl and curcumin diketimines as DNA intercalators and their electrochemical behavior under Nafion and clay modified electrodes.

  Journal of inorganic biochemistry 20050301

• EF24, a novel synthetic curcumin analog, induces apoptosis in cancer cells via a redox-dependent mechanism.

  Anti-cancer drugs 20050301

• Nutraceuticals as anti-angiogenic agents: hopes and reality.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20050301

• Transcription factors as targets of the anti-inflammatory treatment. A cell culture study with extracts from some Mediterranean diet plants.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20050301

• Induction of apoptosis by curcumin and its implications for cancer therapy.

  Current cancer drug targets 20050301

• Sensitization of taxol-induced apoptosis by curcumin involves down-regulation of nuclear factor-kappaB and the serine/threonine kinase Akt and is independent of tubulin polymerization.

  The Journal of biological chemistry 20050225

• Curcuminoids and sesquiterpenoids in turmeric (Curcuma longa L.) suppress an increase in blood glucose level in type 2 diabetic KK-Ay mice.

  Journal of agricultural and food chemistry 20050223

• Curcumin stimulates cystic fibrosis transmembrane conductance regulator Cl- channel activity.

  The Journal of biological chemistry 20050218

• Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo.

  The Journal of biological chemistry 20050218

• Effects of dietary chemopreventive phytochemicals on P-glycoprotein function.

  Biochemical and biophysical research communications 20050218

• Differential activation of heme oxygenase-1 by chalcones and rosolic acid in endothelial cells.

  The Journal of pharmacology and experimental therapeutics 20050201

• Detection and quantitation of curcumin in mouse lung cell cultures by matrix-assisted laser desorption ionization time of flight mass spectrometry.

  Analytical biochemistry 20050201

• Curcumin treatment enhances the repair and regeneration of wounds in mice exposed to hemibody gamma-irradiation.

  Plastic and reconstructive surgery 20050201

• Curcumin: a new radio-sensitizer of squamous cell carcinoma cells.

  Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 20050201

• Gene expression profiling identifies activating transcription factor 3 as a novel contributor to the proapoptotic effect of curcumin.

  Molecular cancer therapeutics 20050201

• Antioxidative constituents of Etlingera elatior.

  Journal of natural products 20050201

• Successful application of TD-DFT in transient absorption spectra assignment.

  Organic letters 20050120

• Curcumin for malaria therapy.

  Biochemical and biophysical research communications 20050114

• Xanthorrhizol has a potential to attenuate the high dose cisplatin-induced nephrotoxicity in mice.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20050101

• Effects of dietary quillaja saponin and curcumin on the performance and immune status of weaned piglets.

  Journal of animal science 20050101

• Correction of the CF defect by curcumin: hypes and disappointments.

  BioEssays : news and reviews in molecular, cellular and developmental biology 20050101

• Curcumin induces glutathione biosynthesis and inhibits NF-kappaB activation and interleukin-8 release in alveolar epithelial cells: mechanism of free radical scavenging activity.

  Antioxidants & redox signaling 20050101

• Consumption of the putative chemopreventive agent curcumin by cancer patients: assessment of curcumin levels in the colorectum and their pharmacodynamic consequences.

  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20050101

• Protracted lithium treatment protects against the ER stress elicited by thapsigargin in rat PC12 cells: roles of intracellular calcium, GRP78 and Bcl-2.

  The pharmacogenomics journal 20050101

• [Effects of combined use of curcumin and catechin on cyclooxygenase-2 mRNA expression in dimethylhydrazine-induced rat colon carcinogenesis].

  Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20050101

• Water-soluble antioxidants improve the antioxidant and anticancer activity of low concentrations of curcumin in human leukemia cells.

  Die Pharmazie 20050101

• Influence of dietary spices on the fluidity of erythrocytes in hypercholesterolaemic rats.

  The British journal of nutrition 20050101

• Antiangiogenic agents: studies on fumagillin and curcumin analogs.

  Current pharmaceutical design 20050101

• Effects of TNF-alpha and curcumin on the expression of thrombomodulin and endothelial protein C receptor in human endothelial cells.

  Thrombosis research 20050101

• Re-evaluation of cytotoxicity and iron chelation activity of three beta-diketones by semiempirical molecular orbital method.

  In vivo (Athens, Greece) 20050101

• Curcumin impregnation improves the mechanical properties and reduces the inflammatory response associated with poly(L-lactic acid) fiber.

  Journal of biomaterials science. Polymer edition 20050101

• Protective effect of curcumin during selenium induced toxicity on dehydrogenases in hepatic tissue.

  Indian journal of physiology and pharmacology 20050101

• PARP cleavage and caspase activity to assess chemosensitivity.

  Methods in molecular medicine 20050101

• New developments in the realm of complementary medicine.

  The journal of supportive oncology 20050101

• Effect of bis[curcumino]oxovanadium complex on non-diabetic and streptozotocin-induced diabetic rats.

  Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 20050101

• Pathologic alterations detected in acute pancreatitis induced by sodium taurocholate in rats and therapeutic effects of curcumin, ciprofloxacin and metronidazole combination.

  Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 20050101

• Novel curcumin- and emodin-related compounds identified by in silico 2D/3D conformer screening induce apoptosis in tumor cells.

  BMC cancer 20050101

• Expression profiles of apoptotic genes induced by curcumin in human breast cancer and mammary epithelial cell lines.

  Anticancer research 20050101

• Effect of curcumin on immune function of mice.

  Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20050101

• Modulatory effects of curcumin and curcumin analog on circulatory lipid profiles during nicotine-induced toxicity in Wistar rats.

  Journal of medicinal food 20050101

• Effect of photo-irradiated curcumin treatment against oxidative stress in streptozotocin-induced diabetic rats.

  Journal of medicinal food 20050101

• Comparative effects of curcumin and its analog on alcohol- and polyunsaturated fatty acid-induced alterations in circulatory lipid profiles.

  Journal of medicinal food 20050101

• Antiangiogenic activity of curcumin in hepatocellular carcinoma cells implanted nude mice.

  Clinical hemorheology and microcirculation 20050101

• Effect of tetrahydrocurcumin on erythromycin estolate-induced lipid peroxidation in rats.

  Journal of basic and clinical physiology and pharmacology 20050101

• Amelioration of immune cell number depletion and potentiation of depressed detoxification system of tumor-bearing mice by curcumin.

  Cancer detection and prevention 20050101

• Radioprotection of turmeric extracts in bacterial system.

  Acta biologica Hungarica 20050101

• Anticancer effect of curcumin on human B cell non-Hodgkin's lymphoma.

  Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20050101

• Zyflamend, a unique herbal preparation with nonselective COX inhibitory activity, induces apoptosis of prostate cancer cells that lack COX-2 expression.

  Nutrition and cancer 20050101

• Curcumin, a diferuloylmethane, attenuates cyclosporine-induced renal dysfunction and oxidative stress in rat kidneys.

  BMC pharmacology 20050101

• Effects of water-soluble antioxidants and MAPKK/MEK inhibitor on curcumin-induced apoptosis in HL-60 human leukemic cells.

  Asian Pacific journal of cancer prevention : APJCP 20050101

• Immunomodulatory effects of curcumin.

  Immunopharmacology and immunotoxicology 20050101

• Induction of cytotoxicity and apoptosis and inhibition of cyclooxygenase-2 gene expression, by curcumin and its analog, alpha-diisoeugenol.

  Anticancer research 20050101

• Curcumin inhibits phorbol ester-induced up-regulation of cyclooxygenase-2 and matrix metalloproteinase-9 by blocking ERK1/2 phosphorylation and NF-kappaB transcriptional activity in MCF10A human breast epithelial cells.

  Antioxidants & redox signaling 20050101

• Curcumin differentially sensitizes malignant glioma cells to TRAIL/Apo2L-mediated apoptosis through activation of procaspases and release of cytochrome c from mitochondria.

  Journal of experimental therapeutics & oncology 20050101

• Effect of tetrahydrocurcumin on blood glucose, plasma insulin and hepatic key enzymes in streptozotocin induced diabetic rats.

  Journal of basic and clinical physiology and pharmacology 20050101

• Chemosensitization of hormone-refractory prostate cancer cells by curcumin to TRAIL-induced apoptosis.

  Journal of experimental therapeutics & oncology 20050101

• [Preventive role of curcumin in lung cancer].

  Przeglad lekarski 20050101

• Preparation of curcumin prodrugs and their in vitro anti-tumor activities.

  Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20050101

• Expression of the constitutively activated RelA/NF-kappaB in human astrocytic tumors and the in vitro implication in the regulation of urokinase-type plasminogen activator, migration, and invasion.

  Brain tumor pathology 20050101

• Thapsigargin or curcumin does not promote maturation of processing mutants of the ABC transporters, CFTR, and P-glycoprotein.

  Biochemical and biophysical research communications 20041210

• Nonsteroidal anti-inflammatory agents differ in their ability to suppress NF-kappaB activation, inhibition of expression of cyclooxygenase-2 and cyclin D1, and abrogation of tumor cell proliferation.

  Oncogene 20041209

• Curcumin, a novel p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription.

  The Journal of biological chemistry 20041203

• Prooxidant activity of curcumin: copper-dependent formation of 8-hydroxy-2'-deoxyguanosine in DNA and induction of apoptotic cell death.

  Toxicology in vitro : an international journal published in association with BIBRA 20041201

• Epidermal growth factor stimulates urokinase-type plasminogen activator expression in human gingival fibroblasts. Possible modulation by genistein and curcumin.

  Journal of periodontal research 20041201

• Complementary inhibition of synoviocyte, smooth muscle cell or mouse lymphoma cell proliferation by a vanadyl curcumin complex compared to curcumin alone.

  Journal of inorganic biochemistry 20041201

• Curcumin, the active constituent of turmeric, inhibits amyloid peptide-induced cytochemokine gene expression and CCR5-mediated chemotaxis of THP-1 monocytes by modulating early growth response-1 transcription factor.

  Journal of neurochemistry 20041201

• Curcumin protects mitochondria from oxidative damage and attenuates apoptosis in cortical neurons.

  Acta pharmacologica Sinica 20041201

• Curcumin inhibits NF-kappaB activation and reduces the severity of experimental steatohepatitis in mice.

  Journal of hepatology 20041201

• Chemical genetics for therapeutic target mining.

  Expert opinion on therapeutic targets 20041201

• [Induction of apoptosis in human nasopharyngeal carcinoma cell line CNE-2Z by curcumin].

  Ai zheng = Aizheng = Chinese journal of cancer 20041201

• [Modulation of intestinal mucosal inflammatory factors by curcumin in rats with colitis].

  Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20041201

• Curcumin blocks homocysteine-induced endothelial dysfunction in porcine coronary arteries.

  Journal of vascular surgery 20041201

• In vivo modulation of signaling factors involved in cell survival.

  Journal of radiation research 20041201

• [Curcumin inhibits the proliferation of cultured human fetal retinal pigment epithelium cells].

  Yan ke xue bao = Eye science 20041201

• Curcumin stability and its effect on glutathione S-transferase P1-1 mRNA expression in K562 cells.

  Annals of the New York Academy of Sciences 20041201

• Effects of curcumin (diferuloylmethane) on nuclear factor kappaB signaling in interleukin-1beta-stimulated chondrocytes.

  Annals of the New York Academy of Sciences 20041201

• [Research of anti-proliferation of curcumin on A549 human lung cancer cells and its mechanism].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20041201

• [Study on preparation of the inclusion compound of curcumin with beta-cyclodextrin].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20041201

• Rho/Rhotekin-mediated NF-kappaB activation confers resistance to apoptosis.

  Oncogene 20041118

• Activation of PPARgamma is required for curcumin to induce apoptosis and to inhibit the expression of extracellular matrix genes in hepatic stellate cells in vitro.

  The Biochemical journal 20041115

• Nuclear factor-kappaB and IkappaB kinase are constitutively active in human pancreatic cells, and their down-regulation by curcumin (diferuloylmethane) is associated with the suppression of proliferation and the induction of apoptosis.

  Cancer 20041115

• Biochemical mechanism of modulation of human P-glycoprotein (ABCB1) by curcumin I, II, and III purified from Turmeric powder.

  Biochemical pharmacology 20041115

• Anti-allergic principles from Thai zedoary: structural requirements of curcuminoids for inhibition of degranulation and effect on the release of TNF-alpha and IL-4 in RBL-2H3 cells.

  Bioorganic & medicinal chemistry 20041115

• Nitric oxide is synthesized in acute leukemia cells after exposure to phenolic antioxidants and initially protects against mitochondrial membrane depolarization.

  Cancer letters 20041108

• Curcumin induces c-jun N-terminal kinase-dependent apoptosis in HCT116 human colon cancer cells.

  Carcinogenesis 20041101

• Curcumin-induced GADD153 gene up-regulation in human colon cancer cells.

  Carcinogenesis 20041101

• Localization and functional analyses of the MLC1 protein involved in megalencephalic leukoencephalopathy with subcortical cysts.

  Human molecular genetics 20041101

• Protection of liver cells from ethanol cytotoxicity by curcumin in liver slice culture in vitro.

  Journal of ethnopharmacology 20041101

• Induction of proteasome expression in skeletal muscle is attenuated by inhibitors of NF-kappaB activation.

  British journal of cancer 20041101

• Biologic evaluation of curcumin and structural derivatives in cancer chemoprevention model systems.

  Phytochemistry 20041101

• The spice of life for cystic fibrosis.

  Gastroenterology 20041101

• [Experimental study on anticancer effect of curcumin on Raji cells in vitro].

  Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20041101

• [Determination of curcumin in urine by capillary electrophoresis].

  Se pu = Chinese journal of chromatography 20041101

• [The effect of curcumin on bladder cancer cell line EJ in vitro].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20041101

• Circular dichroism spectroscopic studies reveal pH dependent binding of curcumin in the minor groove of natural and synthetic nucleic acids.

  Organic & biomolecular chemistry 20041021

• Human glutamate cysteine ligase gene regulation through the electrophile response element.

  Free radical biology & medicine 20041015

• Phase I clinical trial of oral curcumin: biomarkers of systemic activity and compliance.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20041015

• Amelioration of genotoxic damage by certain phytoproducts in human lymphocyte cultures.

  Chemico-biological interactions 20041015

• Molecular responses of vascular smooth muscle cells and phagocytes to curcumin-eluting bioresorbable stent materials.

  Biomaterials 20041001

• Curcumin modulates free radical quenching in myocardial ischaemia in rats.

  The international journal of biochemistry & cell biology 20041001

• Ectopic expression of Bcl-XL or Ku70 protects human colon cancer cells (SW480) against curcumin-induced apoptosis while their down-regulation potentiates it.

  Carcinogenesis 20041001

• The arachidonic acid 5-lipoxygenase inhibitor nordihydroguaiaretic acid inhibits tumor necrosis factor alpha activation of microglia and extends survival of G93A-SOD1 transgenic mice.

  Journal of neurochemistry 20041001

• Some like it hot: curcumin and CFTR.

  Trends in molecular medicine 20041001

• A new curcumin derivative, HBC, interferes with the cell cycle progression of colon cancer cells via antagonization of the Ca2+/calmodulin function.

  Chemistry & biology 20041001

• [Effect of curcumin on STAT5 signaling pathway in primary CML cells].

  Zhongguo shi yan xue ye xue za zhi 20041001

• Curcumin inhibits mitogen stimulated lymphocyte proliferation, NFkappaB activation, and IL-2 signaling.

  The Journal of surgical research 20041001

• Evidence against the rescue of defective DeltaF508-CFTR cellular processing by curcumin in cell culture and mouse models.

  The Journal of biological chemistry 20040924

• Inhibition of growth and survival of human head and neck squamous cell carcinoma cells by curcumin via modulation of nuclear factor-kappaB signaling.

  International journal of cancer 20040920

• Curcumin does not stimulate cAMP-mediated chloride transport in cystic fibrosis airway epithelial cells.

  Biochemical and biophysical research communications 20040917

• Antioxidants regulate normal human keratinocyte differentiation.

  Biochemical pharmacology 20040915

• Abnormal solvent effects on hydrogen atom abstraction. 2. Resolution of the curcumin antioxidant controversy. The role of sequential proton loss electron transfer.

  The Journal of organic chemistry 20040903

• Chiral benzyl centers through asymmetric catalysis. a three-step synthesis of (R)-(-)-alpha-curcumene via asymmetric hydrovinylation.

  Organic letters 20040902

• Modulation of arachidonic acid metabolism by curcumin and related beta-diketone derivatives: effects on cytosolic phospholipase A(2), cyclooxygenases and 5-lipoxygenase.

  Carcinogenesis 20040901

• Curcumin impairs tumor suppressor p53 function in colon cancer cells.

  Carcinogenesis 20040901

• In vitro and in vivo anti-tumoral effect of curcumin against melanoma cells.

  International journal of cancer 20040901

• Curcumin and cystic fibrosis.

  Journal of pediatric gastroenterology and nutrition 20040901

• Paeoniflorin induces apoptosis of lymphocytes through a redox-linked mechanism.

  Journal of cellular biochemistry 20040901

• Effect of curcumin on normal and tumor cells: role of glutathione and bcl-2.

  Molecular cancer therapeutics 20040901

• Evaluation of DNA damage in mice topically exposed to total particulate matter from mainstream and sidestream smoke from cigarettes and bidis.

  Mutagenesis 20040901

• [Study on the SFE condition for curcumin in Curcuma longa].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20040901

• Peroxynitrite interaction with curcumin solubilized in ethanolic solution.

  Cellular and molecular biology (Noisy-le-Grand, France) 20040901

• Synthetic curcumin analogs inhibit activator protein-1 transcription and tumor-induced angiogenesis.

  Biochemical and biophysical research communications 20040820

• Comparative effects of curcumin and an analog of curcumin on alcohol and PUFA induced oxidative stress.

  Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20040820

• Effect of curcumin on gelatinase A (MMP-2) activity in B16F10 melanoma cells.

  Cancer letters 20040810

• Can curcumin cure cystic fibrosis?

  The New England journal of medicine 20040805

• Mining MEDLINE for implicit links between dietary substances and diseases.

  Bioinformatics (Oxford, England) 20040804

• Synthesis of symmetrical bis-alkynyl or alkyl pyridine and thiophene derivatives and their antiangiogenic activities.

  Bioorganic & medicinal chemistry letters 20040802

• Cyclic mechanical stretch augments both interleukin-8 and monocyte chemotactic protein-3 production in the cultured human uterine cervical fibroblast cells.

  Molecular human reproduction 20040801

• Curcumin inhibits cell motility and alters microfilament organization and function in prostate cancer cells.

  Cell motility and the cytoskeleton 20040801

• Curcumin and derivatives.

  Acta crystallographica. Section C, Crystal structure communications 20040801

• Hydrogen-bonding and C-H...pi interactions in 1,7-bis(4-hydroxy-3-methoxyphenyl)heptane-3,5-dione (tetrahydrocurcumin).

  Acta crystallographica. Section C, Crystal structure communications 20040801

• Comparison of the anti-proliferation and apoptosis-induction activities of sulindac, celecoxib, curcumin, and nifedipine in mismatch repair-deficient cell lines.

  Journal of the Formosan Medical Association = Taiwan yi zhi 20040801

• Curcumin interaction with copper and iron suggests one possible mechanism of action in Alzheimer's disease animal models.

  Journal of Alzheimer's disease : JAD 20040801

• Synthesis and biological evaluation of novel curcumin analogs as anti-cancer and anti-angiogenesis agents.

  Bioorganic & medicinal chemistry 20040715

• Expression of angiogenic factors vascular endothelial growth factor and interleukin-8/CXCL8 is highly responsive to ambient glutamine availability: role of nuclear factor-kappaB and activating protein-1.

  Cancer research 20040715

• Fluoride curcumin derivatives: new mitochondrial uncoupling agents.

  FEBS letters 20040702

• Curcumin-induced apoptosis in scleroderma lung fibroblasts: role of protein kinase cepsilon.

  American journal of respiratory cell and molecular biology 20040701

• Role of curcumin, a naturally occurring phenolic compound of turmeric in accelerating the repair of excision wound, in mice whole-body exposed to various doses of gamma-radiation.

  The Journal of surgical research 20040701

• Immunomodulatory activity of curcumin: suppression of lymphocyte proliferation, development of cell-mediated cytotoxicity, and cytokine production in vitro.

  Biochemical pharmacology 20040701

• Curcumin blocks multiple sites of the TGF-beta signaling cascade in renal cells.

  Kidney international 20040701

• Human UDP-glucuronosyltransferases show atypical metabolism of mycophenolic acid and inhibition by curcumin.

  Drug metabolism and disposition: the biological fate of chemicals 20040701

• Solvatochromic correlations and ground- and excited-state dipole moments of curcuminoid dyes.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20040701

• Curcumin sensitizes prostate cancer cells to tumor necrosis factor-related apoptosis-inducing ligand/Apo2L by inhibiting nuclear factor-kappaB through suppression of IkappaBalpha phosphorylation.

  Molecular cancer therapeutics 20040701

• Curcumin allergy in relation to yellow chlorhexidine solution used for skin disinfection prior to surgery.

  Contact dermatitis 20040701

• Suppression of protein kinase C and nuclear oncogene expression as possible action mechanisms of cancer chemoprevention by Curcumin.

  Archives of pharmacal research 20040701

• Curcumin influences hepatic expression patterns of matrix metalloproteinases in liver toxicity.

  The Italian journal of biochemistry 20040701

• Curcumin ameliorates oxidative stress during nicotine-induced lung toxicity in Wistar rats.

  The Italian journal of biochemistry 20040701

• Phytochemical-induced changes in gene expression of carcinogen-metabolizing enzymes in cultured human primary hepatocytes.

  Xenobiotica; the fate of foreign compounds in biological systems 20040701

• [Preparative separation of curcumin from turmeric by column chromatography].

  Se pu = Chinese journal of chromatography 20040701

• Therapeutic potential of curcumin in prostate cancer--V: Interference with the osteomimetic properties of hormone refractory C4-2B prostate cancer cells.

  The Prostate 20040615

• Induced circular dichroism spectra reveal binding of the antiinflammatory curcumin to human alpha1-acid glycoprotein.

  Bioorganic & medicinal chemistry 20040615

• The effect of curcumin on cadmium-induced oxidative damage and trace elements level in the liver of rats and mice.

  Toxicology letters 20040615

• Green tea polyphenol and curcumin inversely regulate human involucrin promoter activity via opposing effects on CCAAT/enhancer-binding protein function.

  The Journal of biological chemistry 20040604

• Molecular cloning and characterization of a glucosyltransferase catalyzing glucosylation of curcumin in cultured Catharanthus roseus cells.

  FEBS letters 20040604

• Induction of manganese-superoxide dismutase by YS 51, a synthetic 1-(beta-naphtylmethyl)6,7-dihydroxy- 1,2,3,4-tetrahydroisoquinoline alkaloid: implication for anti-inflammatory actions.

  Pharmacology 20040601

• Inhibition of nuclear factor-kappaB and nitric oxide by curcumin induces G2/M cell cycle arrest and apoptosis in human melanoma cells.

  Melanoma research 20040601

• Spicy treatment for cystic fibrosis.

  Lab animal 20040601

• Interventions in aging and age-associated pathologies by means of nutritional approaches.

  Annals of the New York Academy of Sciences 20040601

• Antioxidant effect of curcumin in selenium induced cataract of Wistar rats.

  Indian journal of experimental biology 20040601

• Carboplatin induces apoptotic cell death through downregulation of constitutively active nuclear factor-kappaB in human HPV-18 E6-positive HEp-2 cells.

  Biochemical and biophysical research communications 20040528

• Induction of apoptosis in human lung cancer cells by curcumin.

  Cancer letters 20040528

• Curcumin (diferuloylmethane) inhibits receptor activator of NF-kappa B ligand-induced NF-kappa B activation in osteoclast precursors and suppresses osteoclastogenesis.

  Journal of immunology (Baltimore, Md. : 1950) 20040515

• Dermal wound healing processes with curcumin incorporated collagen films.

  Biomaterials 20040501

• Protective role of tetrahydrocurcumin against erythromycin estolate-induced hepatotoxicity.

  Pharmacological research 20040501

• Anti-apoptotic effects of curcumin on photosensitized human epidermal carcinoma A431 cells.

  Journal of cellular biochemistry 20040501

• Antioxidant status of red blood cells and liver in hypercholesterolemic rats fed hypolipidemic spices.

  International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20040501

• Curcumin, a major constituent of turmeric, corrects cystic fibrosis defects.

  Science (New York, N.Y.) 20040423

• Glucose enhances human macrophage LOX-1 expression: role for LOX-1 in glucose-induced macrophage foam cell formation.

  Circulation research 20040416

• Curcumin blocks NF-kappaB and the motogenic response in Helicobacter pylori-infected epithelial cells.

  Biochemical and biophysical research communications 20040416

• Nuclear factor-kappaB and STAT3 are constitutively active in CD138+ cells derived from multiple myeloma patients, and suppression of these transcription factors leads to apoptosis.

  Blood 20040415

• Interleukin-17 signal transduction pathways implicated in inducing matrix metalloproteinase-3, -13 and aggrecanase-1 genes in articular chondrocytes.

  Cellular signalling 20040401

• Effects of curcumin and curcumin derivatives on mitochondrial permeability transition pore.

  Free radical biology & medicine 20040401

• Determination of acidity constants of curcumin in aqueous solution and apparent rate constant of its decomposition.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20040401

• Spectrophotometric and electrochemical determination of the formation constants of the complexes Curcumin-Fe(III)-water and Curcumin-Fe(II)-water.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20040401

• [Effects of Smac gene overexpression on chemotherapeutic sensitivity of gastric cancer cell line MKN-45].

  Ai zheng = Aizheng = Chinese journal of cancer 20040401

• Reactions of superoxide radicals with curcumin: probable mechanisms by optical spectroscopy and EPR.

  Free radical research 20040401

• Inhibition of proteasomal function by curcumin induces apoptosis through mitochondrial pathway.

  The Journal of biological chemistry 20040319

• Curcumin has potent anti-amyloidogenic effects for Alzheimer's beta-amyloid fibrils in vitro.

  Journal of neuroscience research 20040315

• Hypoxic up-regulation of triosephosphate isomerase expression in mouse brain capillary endothelial cells.

  Archives of biochemistry and biophysics 20040315

• Detection of curcumin and its metabolites in hepatic tissue and portal blood of patients following oral administration.

  British journal of cancer 20040308

• Sulindac sulfide and caffeic acid phenethyl ester suppress the motility of lung adenocarcinoma cells promoted by transforming growth factor-beta through Akt inhibition.

  Journal of cancer research and clinical oncology 20040301

• A novel homologous recombination system to study 92 kDa type IV collagenase transcription demonstrates that the NF-kappaB motif drives the transition from a repressed to an activated state of gene expression.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040301

• PDGF-BB enhances alpha1beta1 integrin-mediated activation of the ERK/AP-1 pathway involved in collagen matrix remodeling by rat mesangial cells.

  Journal of cellular physiology 20040301

• TNF-alpha-induced increase in intestinal epithelial tight junction permeability requires NF-kappa B activation.

  American journal of physiology. Gastrointestinal and liver physiology 20040301

• Curcumin suppresses lipopolysaccharide-induced cyclooxygenase-2 expression by inhibiting activator protein 1 and nuclear factor kappab bindings in BV2 microglial cells.

  Journal of pharmacological sciences 20040301

• Effect of curcumin on radiation-impaired healing of excisional wounds in mice.

  Journal of wound care 20040301

• Manganese complexes of curcumin analogues: evaluation of hydroxyl radical scavenging ability, superoxide dismutase activity and stability towards hydrolysis.

  Free radical research 20040301

• Characterization of curcumin-PVP solid dispersion obtained by spray drying.

  International journal of pharmaceutics 20040301

• [Effect of curcumin on STAT5 signaling molecule in K562 cells].

  Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20040301

• Curcumin, a multi-functional chemopreventive agent, blocks growth of colon cancer cells by targeting beta-catenin-mediated transactivation and cell-cell adhesion pathways.

  Journal of molecular histology 20040301

• [Studies on photoluminescence characteristics of curcumin in acrylamide polymer].

  Guang pu xue yu guang pu fen xi = Guang pu 20040301

• Curcumin confers radiosensitizing effect in prostate cancer cell line PC-3.

  Oncogene 20040226

• Determination of binding constant of transcription factor myc-max/max-max and E-box DNA: the effect of inhibitors on the binding.

  Biochimica et biophysica acta 20040224

• Inhibition of B(a)P induced strand breaks in presence of curcumin.

  Mutation research 20040214

• P-glycoprotein expression does not change the apoptotic pathway induced by curcumin in HL-60 cells.

  Cancer chemotherapy and pharmacology 20040201

• Ectopic expression of Hsp70 confers resistance and silencing its expression sensitizes human colon cancer cells to curcumin-induced apoptosis.

  Carcinogenesis 20040201

• Role of curcumin and the inhibition of NF-kappaB in the onset of chemotherapy-induced mucosal barrier injury.

  Leukemia 20040201

• Through metal binding, curcumin protects against lead- and cadmium-induced lipid peroxidation in rat brain homogenates and against lead-induced tissue damage in rat brain.

  Journal of inorganic biochemistry 20040201

• Evaluation of the nitric oxide radical scavenging activity of manganese complexes of curcumin and its derivative.

  Biological & pharmaceutical bulletin 20040201

• Curcumin ameliorates left ventricular function in rabbits with pressure overload: inhibition of the remodeling of the left ventricular collagen network associated with suppression of myocardial tumor necrosis factor-alpha and matrix metalloproteinase-2 expression.

  Biological & pharmaceutical bulletin 20040201

• Modification of radiation-induced acute oral mucositis in the rat.

  International journal of radiation biology 20040201

• All-trans retinoic acid potentiates Taxotere-induced cell death mediated by Jun N-terminal kinase in breast cancer cells.

  Oncogene 20040115

• Differential and special properties of the major human UGT1-encoded gastrointestinal UDP-glucuronosyltransferases enhance potential to control chemical uptake.

  The Journal of biological chemistry 20040109

• Neuroprotective effect of curcumin in middle cerebral artery occlusion induced focal cerebral ischemia in rats.

  Life sciences 20040109

• Anti-invasive gene expression profile of curcumin in lung adenocarcinoma based on a high throughput microarray analysis.

  Molecular pharmacology 20040101

• Synthesis of curcumin analogues as potential antioxidant, cancer chemopreventive agents.

  Archiv der Pharmazie 20040101

• Analysis of transcription factor remodeling in phase II gene expression with curcumin.

  Methods in enzymology 20040101

• Modulation of human multidrug-resistance MDR-1 gene by natural curcuminoids.

  BMC cancer 20040101

• Biological properties of curcumin-cellular and molecular mechanisms of action.

  Critical reviews in food science and nutrition 20040101

• Cytotoxicity, ROS-generation activity and radical-scavenging activity of curcumin and related compounds.

  Anticancer research 20040101

• Curcumin and resveratrol induce apoptosis and nuclear translocation and activation of p53 in human neuroblastoma.

  Anticancer research 20040101

• Evaluation of radioprotective action of compounds using Saccharomyces cerevisiae.

  Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20040101

• Growth-inhibitory effects of curcumin on ovary cancer cells and its mechanisms.

  Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20040101

• Quantitative determination of curcuminoids in Curcuma rhizomes and rapid differentiation of Curcuma domestica Val. and Curcuma xanthorrhiza Roxb. by capillary electrophoresis.

  Phytochemical analysis : PCA 20040101

• Inhibition of colonic aberrant crypt foci by curcumin in rats is affected by age.

  Nutrition and cancer 20040101

• AP-1 complexes mediate oxidized LDL-induced overproduction of TGF-beta(1) in rat mesangial cells.

  Cell biochemistry and function 20040101

• [Curcumin as method of choice for cystic fibrosis?].

  Pharmazie in unserer Zeit 20040101

• Curcumin inhibits the growth of AGS human gastric carcinoma cells in vitro and shows synergism with 5-fluorouracil.

  Journal of medicinal food 20040101

• Prevention and repair of DNA damage by selected phytochemicals as measured by single cell gel electrophoresis.

  Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20040101

• Sulfur free radical reactivity with curcumin as reference for evaluating antioxidant properties of medicinal zingiberales.

  Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20040101

• Interactive effects of saffron with garlic and curcumin against cyclophosphamide induced genotoxicity in mice.

  Asia Pacific journal of clinical nutrition 20040101

• [Effect of curcumin on extracellular matrix accumulation in the glomeruli in nephrotoxic sera nephritis rats].

  Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20040101

• Influence of dietary curcumin, capsaicin and garlic on the antioxidant status of red blood cells and the liver in high-fat-fed rats.

  Annals of nutrition & metabolism 20040101

• Phytoestrogens in common herbs regulate prostate cancer cell growth in vitro.

  Nutrition and cancer 20040101

• Modulatory effects of curcumin on lipid peroxidation and antioxidant status during nicotine-induced toxicity.

  Polish journal of pharmacology 20040101

• Hepatoprotective effect of sesquiterpenes in turmeric.

  BioFactors (Oxford, England) 20040101

• Cancer prevention by antioxidants.

  BioFactors (Oxford, England) 20040101

• Inhibition of nicotine-induced toxicity by curcumin and curcumin analog: a comparative study.

  Journal of medicinal food 20040101

• Matrix metalloproteinase-2: mechanism and regulation of NF-kappaB-mediated activation and its role in cell motility and ECM-invasion.

  Glycoconjugate journal 20040101

• Photo-irradiated curcumin supplementation in streptozotocin-induced diabetic rats: effect on lipid peroxidation.

  Therapie 20040101

• Direct inhibitory effect of curcumin on Src and focal adhesion kinase activity.

  Biochemical pharmacology 20031215

• Manganese complexes of curcumin and its derivatives: evaluation for the radical scavenging ability and neuroprotective activity.

  Free radical biology & medicine 20031215

• Production of unnatural glucosides of curcumin with drastically enhanced water solubility by cell suspension cultures of Catharanthus roseus.

  FEBS letters 20031204

• Isolation and characterization of human esophageal microvascular endothelial cells: mechanisms of inflammatory activation.

  American journal of physiology. Gastrointestinal and liver physiology 20031201

• Rapid transcriptional suppression of rat cytochrome P450 genes by endotoxin treatment and its inhibition by curcumin.

  The Journal of pharmacology and experimental therapeutics 20031201

• In vitro hemocompatibility studies of drug-loaded poly-(L-lactic acid) fibers.

  Biomaterials 20031201

• Curcumin suppresses Janus kinase-STAT inflammatory signaling through activation of Src homology 2 domain-containing tyrosine phosphatase 2 in brain microglia.

  Journal of immunology (Baltimore, Md. : 1950) 20031201

• Curcumin inhibits protease-activated receptor-2 and -4-mediated mast cell activation.

  Clinica chimica acta; international journal of clinical chemistry 20031201

• Screening of the inhibitory effect of vegetable constituents on the aryl hydrocarbon receptor-mediated activity induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin.

  Biological & pharmaceutical bulletin 20031201

• Curcumin-induced inhibition of cellular reactive oxygen species generation: novel therapeutic implications.

  Journal of biosciences 20031201

• Curcumin inhibits ultraviolet light induced human immunodeficiency virus gene expression.

  Molecular and cellular biochemistry 20031201

• Interplay between MRP inhibition and metabolism of MRP inhibitors: the case of curcumin.

  Chemical research in toxicology 20031201

• [Protective effect and mechanism of pretreatment with curcumin on infectious brain edema in rats].

  Zhonghua er ke za zhi = Chinese journal of pediatrics 20031201

• Regulation of expression of stromyelysin-1 by proinflammatory cytokines in mouse brain astrocytes.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20031201

• Cox-2 is needed but not sufficient for apoptosis induced by Cox-2 selective inhibitors in colon cancer cells.

  Apoptosis : an international journal on programmed cell death 20031201

• Protective effect of curcumin against lead neurotoxicity in rat.

  Human & experimental toxicology 20031201

• Curcumin as a DNA topoisomerase II poison.

  Journal of enzyme inhibition and medicinal chemistry 20031201

• Curcumin-induced cell death in two leukemia cell lines: K562 and Jurkat.

  Annals of the New York Academy of Sciences 20031201

• Curcumin inhibits dose-dependently and time-dependently neuroglial cell proliferation and growth.

  Neuro endocrinology letters 20031201

• Some anti-chronic inflammatory compounds are DNA polymerase lambda-specific inhibitors.

  Biochemical pharmacology 20031115

• Accumulation of the amyloid precursor-like protein APLP2 and reduction of APLP1 in retinoic acid-differentiated human neuroblastoma cells upon curcumin-induced neurite retraction.

  Brain research. Molecular brain research 20031106

• Sensitive and rapid isocratic liquid chromatography method for the quantitation of curcumin in plasma.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20031105

• Extraction of essential oil and pigments from Curcuma longa [L] by steam distillation and extraction with volatile solvents.

  Journal of agricultural and food chemistry 20031105

• Synthesis of glycosylcurcuminoids.

  Chemical & pharmaceutical bulletin 20031101

• Biomimetic oxidation of curcumin with hydrogen peroxide catalyzed by 5,10,15,20-tetraarylporphyrinatoiron(III) chlorides in dichloromethane.

  Chemical & pharmaceutical bulletin 20031101

• Enzyme induction and dietary chemicals as approaches to cancer chemoprevention: the Seventh DeWitt S. Goodman Lecture.

  Cancer research 20031101

• Inhibitory effect of curcumin on proliferation of K562 cells involves down-regulation of p210(bcr/abl) initiated Ras signal transduction pathway.

  Acta pharmacologica Sinica 20031101

• [Curcumin inhibited the proliferation and extracellular matrix production of human mesangial cells].

  Zhonghua er ke za zhi = Chinese journal of pediatrics 20031101

• [Inhibitive effect of curcumin and amiloride on the fibrosis of rat hepatic stellate cells induced by oxidative stress].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20031101

• Cellular redistribution of inducible Hsp70 protein in the human and rabbit heart in response to the stress of chronic hypoxia: role of protein kinases,

  The Journal of biological chemistry 20031031

• [Analysis of anti-proliferation of curcumin on human breast cancer cells and its mechanism].

  Zhonghua yi xue za zhi 20031025

• Comparison of yield, composition, and antioxidant activity of turmeric (Curcuma longa L.) extracts obtained using various techniques.

  Journal of agricultural and food chemistry 20031022

• Induction of apoptosis by curcumin: mediation by glutathione S-transferase P1-1 inhibition.

  Biochemical pharmacology 20031015

• Copper modulates activities of genistein, nitric oxide, and curcumin in breast tumor cells.

  Biochemical and biophysical research communications 20031010

• Human wee1 kinase is directly transactivated by and increased in association with c-Fos/AP-1: rheumatoid synovial cells overexpressing these genes go into aberrant mitosis.

  Oncogene 20031009

• Curcumin (diferuloylmethane) inhibits constitutive and IL-6-inducible STAT3 phosphorylation in human multiple myeloma cells.

  Journal of immunology (Baltimore, Md. : 1950) 20031001

• Curcumin inhibits UV irradiation-induced oxidative stress and apoptotic biochemical changes in human epidermoid carcinoma A431 cells.

  Journal of cellular biochemistry 20031001

• Blocking NF-kappaB activation may be an effective strategy in the fever therapy.

  The Japanese journal of physiology 20031001

• Dietary ginger constituents, galanals A and B, are potent apoptosis inducers in Human T lymphoma Jurkat cells.

  Cancer letters 20030925

• Changes in temperature modulate heme oxygenase-1 induction by curcumin in renal epithelial cells.

  Biochemical and biophysical research communications 20030905

• Curcumin inhibits phorbol ester-induced expression of cyclooxygenase-2 in mouse skin through suppression of extracellular signal-regulated kinase activity and NF-kappaB activation.

  Carcinogenesis 20030901

• Design and development of integrase inhibitors as anti-HIV agents.

  Current medicinal chemistry 20030901

• Role of phenolic O-H and methylene hydrogen on the free radical reactions and antioxidant activity of curcumin.

  Free radical biology & medicine 20030901

• Protective effects of curcumin and photo-irradiated curcumin on circulatory lipids and lipid peroxidation products in alcohol and polyunsaturated fatty acid-induced toxicity.

  Phytotherapy research : PTR 20030901

• Curcumin: a potential vaginal contraceptive.

  Contraception 20030901

• Correspondence re: Somasundaram et al., Dietary curcumin inhibits chemotherapy-induced apoptosis in models of human breast cancer. Cancer Res., 62: 3868-3875, 2002.

  Cancer research 20030815

• Protective effects of curcumin against amiodarone-induced pulmonary fibrosis in rats.

  British journal of pharmacology 20030801

• Irreversible inhibition of CD13/aminopeptidase N by the antiangiogenic agent curcumin.

  Chemistry & biology 20030801

• Efficacy and irritancy of enhancers on the in-vitro and in-vivo percutaneous absorption of curcumin.

  The Journal of pharmacy and pharmacology 20030801

• Pharmacological modulation of fatty acid desaturation and of cholesterol biosynthesis in THP-1 cells.

  Lipids 20030801

• [Protective effect of curcumin on experimental liver injury in mice].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20030801

• Efficacies of plant phenolic compounds on sodium butyrate induced anti-tumour activity.

  Indian journal of experimental biology 20030801

• Curcumin attenuates DNB-induced murine colitis.

  American journal of physiology. Gastrointestinal and liver physiology 20030701

• Activation of peroxisome proliferator-activated receptor-gamma contributes to the inhibitory effects of curcumin on rat hepatic stellate cell growth.

  American journal of physiology. Gastrointestinal and liver physiology 20030701

• Structure of curcumin in complex with lipoxygenase and its significance in cancer.

  International journal of molecular medicine 20030701

• Inhibition of nicotine-DNA adduct formation in mice by six dietary constituents.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20030701

• Curcumin (diferuloylmethane) down-regulates cigarette smoke-induced NF-kappaB activation through inhibition of IkappaBalpha kinase in human lung epithelial cells: correlation with suppression of COX-2, MMP-9 and cyclin D1.

  Carcinogenesis 20030701

• Molecular mechanisms of curcumin-induced cytotoxicity: induction of apoptosis through generation of reactive oxygen species, down-regulation of Bcl-XL and IAP, the release of cytochrome c and inhibition of Akt.

  Carcinogenesis 20030701

• Curcumin attenuates allergen-induced airway hyperresponsiveness in sensitized guinea pigs.

  Biological & pharmaceutical bulletin 20030701

• Involvement of p38 MAPK, JNK, p42/p44 ERK and NF-kappaB in IL-1beta-induced chemokine release in human airway smooth muscle cells.

  Respiratory medicine 20030701

• Zingiberene and curcumene in wild tomato.

  Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20030701

• [Study on the effects of curcumin on angiogenesis].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20030701

• Hepatobiliary clearance of labelled mebrofenin in normal and D-galactosamine HCl-induced hepatitis rats and the protective effect of turmeric extract.

  Indian journal of physiology and pharmacology 20030701

• Effect of curcumin on galactose-induced cataractogenesis in rats.

  Molecular vision 20030609

• Translation inhibitors sensitize prostate cancer cells to apoptosis induced by tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) by activating c-Jun N-terminal kinase.

  The Journal of biological chemistry 20030606

• Role of MAPK pathways in light chain-induced cytokine production in human proximal tubule cells.

  American journal of physiology. Renal physiology 20030601

• Curcumin inhibited the arylamines N-acetyltransferase activity, gene expression and DNA adduct formation in human lung cancer cells (A549).

  Toxicology in vitro : an international journal published in association with BIBRA 20030601

• Dietary compounds inhibit proliferation and contraction of keloid and hypertrophic scar-derived fibroblasts in vitro: therapeutic implication for excessive scarring.

  The Journal of trauma 20030601

• Pro-inflammatory agents accumulate during donor liver cold preservation: a study on increased adhesion molecule expression and abrogation by curcumin in cultured endothelial cells.

  Cryobiology 20030601

• Curcumin enhances the immunosuppressive activity of cyclosporine in rat cardiac allografts and in mixed lymphocyte reactions.

  Transplantation proceedings 20030601

• Effects of baicalein, berberine, curcumin and hesperidin on mucin release from airway goblet cells.

  Planta medica 20030601

• Photophysical studies on binding of curcumin to bovine serum albumins.

  Photochemistry and photobiology 20030601

• Enhanced release of IL-1beta and TNF-alpha following endotoxin challenge from rat alveolar macrophages cultured in low-mg(2+) medium.

  Magnesium research 20030601

• Suppression of nitric oxide oxidation to nitrite by curcumin is due to the sequestration of the reaction intermediate nitrogen dioxide, not nitric oxide.

  Nitric oxide : biology and chemistry 20030601

• Antispasmodic effects of curcuminoids on isolated guinea-pig ileum and rat uterus.

  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20030601

• Efficacy of a diarylheptanoid derivative against Leishmania amazonensis.

  Memorias do Instituto Oswaldo Cruz 20030601

• Age-related difference in susceptibility of Apc(Min/+) mice towards the chemopreventive efficacy of dietary aspirin and curcumin.

  British journal of cancer 20030506

• Curcumin activates the haem oxygenase-1 gene via regulation of Nrf2 and the antioxidant-responsive element.

  The Biochemical journal 20030501

• Inhibition of cell survival signal protein kinase B/Akt by curcumin in human prostate cancer cells.

  Journal of cellular biochemistry 20030501

• Cytoprotective and cytotoxic effects of curcumin: dual action on H2O2-induced oxidative cell damage in NG108-15 cells.

  Biological & pharmaceutical bulletin 20030501

• In vitro peroxynitrite scavenging activity of diarylheptanoids from Curcuma longa.

  Phytotherapy research : PTR 20030501

• Curcumin, the major component of food flavour turmeric, reduces mucosal injury in trinitrobenzene sulphonic acid-induced colitis.

  British journal of pharmacology 20030501

• Modulation of inflammatory mediators by ibuprofen and curcumin treatment during chronic inflammation in rat.

  Immunopharmacology and immunotoxicology 20030501

• Arrest of apoptosis in auditory neurons: implications for sensorineural preservation in cochlear implantation.

  Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 20030501

• Efficacy and irritancy of enhancers on the in-vitro and in-vivo percutaneous absorption of curcumin.

  The Journal of pharmacy and pharmacology 20030501

• Inhibition of myeloperoxidase-catalyzed tyrosylation by phenolic antioxidants in vitro.

  Bioscience, biotechnology, and biochemistry 20030501

• 4-Hydroxy-3-methoxybenzoic acid methyl ester: a curcumin derivative targets Akt/NF kappa B cell survival signaling pathway: potential for prostate cancer management.

  Neoplasia (New York, N.Y.) 20030501

• Osteopontin induces nuclear factor kappa B-mediated promatrix metalloproteinase-2 activation through I kappa B alpha /IKK signaling pathways, and curcumin (diferulolylmethane) down-regulates these pathways.

  The Journal of biological chemistry 20030418

• Ruthenium red, inhibitor of mitochondrial Ca2+ uniporter, inhibits curcumin-induced apoptosis via the prevention of intracellular Ca2+ depletion and cytochrome c release.

  Biochemical and biophysical research communications 20030418

• The effect of nanometer size of porous anodic aluminum oxide on adsorption and fluorescence of tetrahydroxyflavanol.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20030401

• [Follicular penetration. An important pathway for topically applied substances].

  Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20030401

• Rapid and selective apoptosis in human leukemic cells induced by Aplidine through a Fas/CD95- and mitochondrial-mediated mechanism.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20030401

• Effects of curcumin on cyclosporine-induced cholestasis and hypercholesterolemia and on cyclosporine metabolism in the rat.

  Planta medica 20030401

• Curcumin is a potent inhibitor of phenol sulfotransferase (SULT1A1) in human liver and extrahepatic tissues.

  Xenobiotica; the fate of foreign compounds in biological systems 20030401

• Contact allergy to tetrahydrocurcumin.

  Contact dermatitis 20030401

• Evidence for phosphorylation requirement for human bilirubin UDP-glucuronosyltransferase (UGT1A1) activity.

  Biochemical and biophysical research communications 20030328

• Curcumin differentially modulates mRNA profiles in Jurkat T and human peripheral blood mononuclear cells.

  Bioorganic & medicinal chemistry 20030320

• Protein kinase CK2 and protein kinase D are associated with the COP9 signalosome.

  The EMBO journal 20030317

• Human colon cancer cells differ in their sensitivity to curcumin-induced apoptosis and heat shock protects them by inhibiting the release of apoptosis-inducing factor and caspases.

  FEBS letters 20030313

• Fungicidal property of Curcuma longa L. rhizome-derived curcumin against phytopathogenic fungi in a greenhouse.

  Journal of agricultural and food chemistry 20030312

• Curcumin alters EpRE and AP-1 binding complexes and elevates glutamate-cysteine ligase gene expression.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030301

• Initial stages of neural regeneration in Helisoma trivolvis are dependent upon PLA2 activity.

  Journal of neurobiology 20030301

• Studies on the role of some synthetic curcuminoid derivatives in the inhibition of tumour specific angiogenesis.

  Journal of experimental & clinical cancer research : CR 20030301

• Hypoxia up-regulates glyceraldehyde-3-phosphate dehydrogenase in mouse brain capillary endothelial cells: involvement of Na+/Ca2+ exchanger.

  Biochimica et biophysica acta 20030217

• Unique, pH-dependent biphasic band shape of the visible circular dichroism of curcumin-serum albumin complex.

  Biochemical and biophysical research communications 20030214

• High glucose-induced, endothelin-dependent fibronectin synthesis is mediated via NF-kappa B and AP-1.

  American journal of physiology. Cell physiology 20030201

• Curcumin prevents alcohol-induced liver disease in rats by inhibiting the expression of NF-kappa B-dependent genes.

  American journal of physiology. Gastrointestinal and liver physiology 20030201

• Curcumin (diferuloylmethane) down-regulates the constitutive activation of nuclear factor-kappa B and IkappaBalpha kinase in human multiple myeloma cells, leading to suppression of proliferation and induction of apoptosis.

  Blood 20030201

• Relevance of mitogen activated protein kinase (MAPK) and phosphotidylinositol-3-kinase/protein kinase B (PI3K/PKB) pathways to induction of apoptosis by curcumin in breast cells.

  Biochemical pharmacology 20030201

• Anticarcinogenic effect of bis-1,7-(2-hydroxyphenyl)-hepta-1,6-diene-3,5-dione a curcumin analog on DMH-induced colon cancer model.

  Pharmacological research 20030201

• Differential regulation of cytokines and transcription factors in liver by curcumin following hemorrhage/resuscitation.

  Shock (Augusta, Ga.) 20030201

• Safety and anti-inflammatory activity of curcumin: a component of tumeric (Curcuma longa).

  Journal of alternative and complementary medicine (New York, N.Y.) 20030201

• Design, synthesis, and biological evaluation of angiogenesis inhibitors: aromatic enone and dienone analogues of curcumin.

  Bioorganic & medicinal chemistry letters 20030106

• Curcumin in plasma and urine: quantitation by high-performance liquid chromatography.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030105

• Inhibition of growth and sensitization to cisplatin-mediated killing of ovarian cancer cells by polyphenolic chemopreventive agents.

  Journal of cellular physiology 20030101

• Curcumin ameliorates ethanol and nonethanol experimental pancreatitis.

  American journal of physiology. Gastrointestinal and liver physiology 20030101

• Curcumin (diferuloyl-methane) enhances tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in LNCaP prostate cancer cells.

  Molecular cancer therapeutics 20030101

• Diferuloylmethane inhibits neutrophil infiltration and improves survival of mice in high-dose endotoxin shock.

  Shock (Augusta, Ga.) 20030101

• In vitro curcumin modulates ferric nitrilotriacetate (Fe-NTA) and hydrogen peroxide (H2O2)-induced peroxidation of microsomal membrane lipids and DNA damage.

  Teratogenesis, carcinogenesis, and mutagenesis 20030101

• Antigenotoxic potential of certain dietary constituents.

  Teratogenesis, carcinogenesis, and mutagenesis 20030101

• Inhibitory effects of the ginsenoside Rg3 on phorbol ester-induced cyclooxygenase-2 expression, NF-kappaB activation and tumor promotion.

  Mutation research 20030101

• No prevention of liver and kidney tumors in Long-Evans Cinnamon rats by dietary curcumin, but inhibition at other sites and of metastases.

  Mutation research 20030101

• Mechanism-based in vitro screening of potential cancer chemopreventive agents.

  Mutation research 20030101

• Curcumin exhibits antimetastatic properties by modulating integrin receptors, collagenase activity, and expression of Nm23 and E-cadherin.

  Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20030101

• Anticancer potential of curcumin: preclinical and clinical studies.

  Anticancer research 20030101

• Dietary supplementation of curcumin enhances antioxidant and phase II metabolizing enzymes in ddY male mice: possible role in protection against chemical carcinogenesis and toxicity.

  Pharmacology & toxicology 20030101

• Suppression of altered hepatic foci development by curcumin in wistar rats.

  Nutrition and cancer 20030101

• Antitumor activity of extract of Zingiber aromaticum and its bioactive sesquiterpenoid zerumbone.

  Nutrition and cancer 20030101

• Comparison of antiproliferative effects of experimental and established antipsoriatic drugs on human keratinocytes, using a simple 96-well-plate assay.

  In vitro cellular & developmental biology. Animal 20030101

• Curcumin decreases the DNA adduct formation, arylamines N-acetyltransferase activity and gene expression in human colon tumor cells (colo 205).

  In vivo (Athens, Greece) 20030101

• The effect of curcumin on mismatch repair (MMR) proteins hMSH2 and hMLH1 after ultraviolet (UV) irradiation on HL-60 cells.

  Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20030101

• Prevention of intrahepatic metastasis by curcumin in an orthotopic implantation model.

  Oncology 20030101

• Protection of pancreatic beta-cell by the potential antioxidant bis-o-hydroxycinnamoyl methane, analogue of natural curcuminoid in experimental diabetes.

  Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20030101

• Curcumin-induced suppression of cell proliferation correlates with down-regulation of cyclin D1 expression and CDK4-mediated retinoblastoma protein phosphorylation.

  Oncogene 20021212

• Beta-catenin-mediated transactivation and cell-cell adhesion pathways are important in curcumin (diferuylmethane)-induced growth arrest and apoptosis in colon cancer cells.

  Oncogene 20021205

• Protection against cancer by plant phenylpropenoids: induction of mammalian anticarcinogenic enzymes.

  Mini reviews in medicinal chemistry 20021201

• Requirement for PIKfyve enzymatic activity in acute and long-term insulin cellular effects.

  Endocrinology 20021201

• Curcumin prevents and ameliorates trinitrobenzene sulfonic acid-induced colitis in mice.

  Gastroenterology 20021201

• Microarray-based analysis of anti-angiogenic activity of demethoxycurcumin on human umbilical vein endothelial cells: crucial involvement of the down-regulation of matrix metalloproteinase.

  Japanese journal of cancer research : Gann 20021201

• [Effects of curcumin on proliferation and apoptosis in human hepatic cells].

  Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20021201

• [Inhibitory effects of curcumin on apoptosis of human ovary cancer cell line A2780 and its molecular mechanism].

  Ai zheng = Aizheng = Chinese journal of cancer 20021201

• Solubility, chemical and photochemical stability of curcumin in surfactant solutions. Studies of curcumin and curcuminoids, XXVIII.

  Die Pharmazie 20021201

• Inhibitory effect of curcumin and its natural analogues on genotoxicity of heterocyclic amines from cooked food.

  Indian journal of experimental biology 20021201

• Inositol 1,3,4-trisphosphate 5/6-kinase associates with the COP9 signalosome by binding to CSN1.

  The Journal of biological chemistry 20021129

• Amyloid-beta induces Smac release via AP-1/Bim activation in cerebral endothelial cells.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20021115

• Antitumor agents. 217. Curcumin analogues as novel androgen receptor antagonists with potential as anti-prostate cancer agents.

  Journal of medicinal chemistry 20021107

• Antitumor agents. Part 214: synthesis and evaluation of curcumin analogues as cytotoxic agents.

  Bioorganic & medicinal chemistry 20021101

• Mitogen-activated protein kinases mediate stretch-induced c-fos mRNA expression in myometrial smooth muscle cells.

  American journal of physiology. Cell physiology 20021101

• Adenovirus-mediated mda-7 gene expression radiosensitizes non-small cell lung cancer cells via TP53-independent mechanisms.

  Molecular therapy : the journal of the American Society of Gene Therapy 20021101

• Cyclic mechanical stretch augments prostacyclin production in cultured human uterine myometrial cells from pregnant women: possible involvement of up-regulation of prostacyclin synthase expression.

  The Journal of clinical endocrinology and metabolism 20021101

• Curcumin induces caspase-3-independent apoptosis in human multidrug-resistant cells.

  Annals of the New York Academy of Sciences 20021101

• Naphthalene toxicity and antioxidant nutrients.

  Toxicology 20021030

• Curcumin inhibits telomerase activity through human telomerase reverse transcritpase in MCF-7 breast cancer cell line.

  Cancer letters 20021008

• New and known symmetrical curcumin derivatives inhibit the formation of Fos-Jun-DNA complex.

  Cancer letters 20021008

• Molecular mechanisms of anti-angiogenic effect of curcumin.

  Biochemical and biophysical research communications 20021004

• Curcumin down-regulates AR gene expression and activation in prostate cancer cell lines.

  International journal of oncology 20021001

• Curcumin activates the aryl hydrocarbon receptor yet significantly inhibits (-)-benzo(a)pyrene-7R-trans-7,8-dihydrodiol bioactivation in oral squamous cell carcinoma cells and oral mucosa.

  Cancer research 20021001

• Nutritional support for chronic myelogenous and other leukemias: a review of the scientific literature.

  Alternative medicine review : a journal of clinical therapeutic 20021001

• [Chemopreventive effect of tea and curcumin on DMBA-induced oral carcinogenesis in hamsters].

  Wei sheng yan jiu = Journal of hygiene research 20021001

• Activations of ERK1/2 and JNK by transforming growth factor beta negatively regulate Smad3-induced alkaline phosphatase activity and mineralization in mouse osteoblastic cells.

  The Journal of biological chemistry 20020927

• Curcumin inhibits interleukin 8 production and enhances interleukin 8 receptor expression on the cell surface:impact on human pancreatic carcinoma cell growth by autocrine regulation.

  Cancer 20020915

• Metal-mediated DNA damage induced by curcumin in the presence of human cytochrome P450 isozymes.

  Archives of biochemistry and biophysics 20020915

• Studies of curcumin and curcuminoids. XXVII. Cyclodextrin complexation: solubility, chemical and photochemical stability.

  International journal of pharmaceutics 20020905

• Hydrazinocurcumin, a novel synthetic curcumin derivative, is a potent inhibitor of endothelial cell proliferation.

  Bioorganic & medicinal chemistry 20020901

• Comparative effects of curcumin and photo-irradiated curcumin on alcohol- and polyunsaturated fatty acid-induced hyperlipidemia.

  Pharmacological research 20020901

• Protective effects of curcumin against ischaemia/reperfusion insult in rat forebrain.

  Pharmacological research 20020901

• Discovery of natural products from Curcuma longa that protect cells from beta-amyloid insult: a drug discovery effort against Alzheimer's disease.

  Journal of natural products 20020901

• Theoretical elucidation on the antioxidant mechanism of curcumin: a DFT study.

  Organic letters 20020822

• Transforming growth factor-beta1 modulates matrix metalloproteinase-9 production through the Ras/MAPK signaling pathway in transformed keratinocytes.

  Biochemical and biophysical research communications 20020816

• Modulation of P-glycoprotein expression and function by curcumin in multidrug-resistant human KB cells.

  Biochemical pharmacology 20020815

• Hydrazinocurcumin, a novel synthetic curcumin derivative, is a potent inhibitor of endothelial cell proliferation.

  Bioorganic & medicinal chemistry 20020801

• Anti-tumor promoting potential of selected spice ingredients with antioxidative and anti-inflammatory activities: a short review.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20020801

• Curcumin inhibits cell cycle progression of immortalized human umbilical vein endothelial (ECV304) cells by up-regulating cyclin-dependent kinase inhibitor, p21WAF1/CIP1, p27KIP1 and p53.

  International journal of oncology 20020801

• Inhibition of 7,12-dimethylbenz[a]anthracene (DMBA)-induced oral carcinogenesis in hamsters by tea and curcumin.

  Carcinogenesis 20020801

• Curcumin's effects on sialic acid level and sialidase activity in Ehrlich ascites tumor bearing mice.

  The Tohoku journal of experimental medicine 20020801

• Capillary electrophoresis with amperometric detection of curcumin in Chinese herbal medicine pretreated by solid-phase extraction.

  Journal of chromatography. A 20020712

• Curcumin (diferuloylmethane), a singlet oxygen ((1)O(2)) quencher.

  Biochemical and biophysical research communications 20020705

• Radioprotective action of curcumin extracted from Curcuma longa LINN: inhibitory effect on formation of urinary 8-hydroxy-2'-deoxyguanosine, tumorigenesis, but not mortality, induced by gamma-ray irradiation.

  International journal of radiation oncology, biology, physics 20020701

• Prostaglandin F(2alpha), cytokines and cyclic mechanical stretch augment matrix metalloproteinase-1 secretion from cultured human uterine cervical fibroblast cells.

  Molecular human reproduction 20020701

• Dietary curcumin inhibits chemotherapy-induced apoptosis in models of human breast cancer.

  Cancer research 20020701

• Curcuma longa extract supplementation reduces oxidative stress and attenuates aortic fatty streak development in rabbits.

  Arteriosclerosis, thrombosis, and vascular biology 20020701

• Activation of Raf-1/MEK-1/2/p42/44(MAPK) cascade alone is sufficient to uncouple LDL receptor expression from cell growth.

  Molecular and cellular biochemistry 20020701

• Integrity of erythrocytes of hypercholesterolemic rats during spices treatment.

  Molecular and cellular biochemistry 20020701

• Bis-1,7-(2-hydroxyphenyl)-hepta-1,6-diene-3,5-dione (a curcumin analog) ameliorates DMH-induced hepatic oxidative stress during colon carcinogenesis.

  Pharmacological research 20020701

• Anticancer activities of curcumin on human Burkitt's lymphoma.

  Zhonghua zhong liu za zhi [Chinese journal of oncology] 20020701

• Curcumin disrupts mitotic spindle structure and induces micronucleation in MCF-7 breast cancer cells.

  Mutation research 20020627

• Lipopolysaccharide-mediated reactive oxygen species and signal transduction in the regulation of interleukin-1 gene expression.

  The Journal of biological chemistry 20020621

• Improved HPLC method for the determination of curcumin, demethoxycurcumin, and bisdemethoxycurcumin.

  Journal of agricultural and food chemistry 20020619

• Curcumin inhibits experimental allergic encephalomyelitis by blocking IL-12 signaling through Janus kinase-STAT pathway in T lymphocytes.

  Journal of immunology (Baltimore, Md. : 1950) 20020615

• Chemopreventive efficacy and pharmacokinetics of curcumin in the min/+ mouse, a model of familial adenomatous polyposis.

  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20020601

• Membrane-type matrix metalloproteinases mediate curcumin-induced cell migration in non-tumorigenic colon epithelial cells differing in Apc genotype.

  Carcinogenesis 20020601

• Anti-tumour studies of metal chelates of synthetic curcuminoids.

  Journal of experimental & clinical cancer research : CR 20020601

• Effect of antioxidants (vitamin C, E and turmeric extract) on methimazole induced hypothyroidism in rats.

  Indian journal of experimental biology 20020601

• Curcumin suppresses activation of NF-kappaB and AP-1 induced by phorbol ester in cultured human promyelocytic leukemia cells.

  Journal of biochemistry and molecular biology 20020531

• Curcumin enhances cytotoxicity of chemotherapeutic agents in prostate cancer cells by inducing p21(WAF1/CIP1) and C/EBPbeta expressions and suppressing NF-kappaB activation.

  The Prostate 20020515

• Relative contribution of NF-kappaB and AP-1 in the modulation by curcumin and pyrrolidine dithiocarbamate of the UVB-induced cytokine expression by keratinocytes.

  Cytokine 20020507

• Involvement of the mitogen-activated protein kinase family in tetracaine-induced PC12 cell death.

  Anesthesiology 20020501

• Basal levels and patterns of anticancer drug-induced activation of nuclear factor-kappaB (NF-kappaB), and its attenuation by tamoxifen, dexamethasone, and curcumin in carcinoma cells.

  Biochemical pharmacology 20020501

• Effect of curcuminoids as anti-inflammatory agents on the hepatic microvascular response to endotoxin.

  Shock (Augusta, Ga.) 20020501

• Medicinal foodstuffs. XXIX. Potent protective effects of sesquiterpenes and curcumin from Zedoariae Rhizoma on liver injury induced by D-galactosamine/lipopolysaccharide or tumor necrosis factor-alpha.

  Biological & pharmaceutical bulletin 20020501

• The molecular mechanisms for the antitumorigenic effect of curcumin.

  Current medicinal chemistry. Anti-cancer agents 20020501

• Structural identification of new curcumin dimers and their contribution to the antioxidant mechanism of curcumin.

  Journal of agricultural and food chemistry 20020424

• The slippage of the Ca2+ pump and its control by anions and curcumin in skeletal and cardiac sarcoplasmic reticulum.

  The Journal of biological chemistry 20020419

• Botanical antioxidants for chemoprevention of photocarcinogenesis.

  Frontiers in bioscience : a journal and virtual library 20020401

• Shogaols from Zingiber officinale protect IMR32 human neuroblastoma and normal human umbilical vein endothelial cells from beta-amyloid(25-35) insult.

  Planta medica 20020401

• Inhibition of interleukin-1-stimulated MAP kinases, activating protein-1 (AP-1) and nuclear factor kappa B (NF-kappa B) transcription factors down-regulates matrix metalloproteinase gene expression in articular chondrocytes.

  Matrix biology : journal of the International Society for Matrix Biology 20020401

• Biodegradable microspheres of curcumin for treatment of inflammation.

  Indian journal of physiology and pharmacology 20020401

• Antimutagenic potential of curcumin on chromosomal aberrations in Wistar rats.

  Mutation research 20020325

• Study on the supramolecular interaction of curcumin and beta-cyclodextrin by spectrophotometry and its analytical application.

  Journal of agricultural and food chemistry 20020313

• Curcumin exerts multiple suppressive effects on human breast carcinoma cells.

  International journal of cancer 20020310

• Caffeic acid phenethyl ester and curcumin: a novel class of heme oxygenase-1 inducers.

  Molecular pharmacology 20020301

• The chemopreventive compound curcumin is an efficient inhibitor of Epstein-Barr virus BZLF1 transcription in Raji DR-LUC cells.

  Molecular carcinogenesis 20020301

• Latent activity of curcumin against leishmaniasis in vitro.

  Biological & pharmaceutical bulletin 20020301

• Effect of curcumin on ethanol-induced stress on mononuclear cells.

  Phytotherapy research : PTR 20020301

• Evaluation of antioxidant properties of root bark of Hemidesmus indicus R. Br. (Anantmul).

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20020301

• Quenching of superoxide ions by curcumin. A mechanistic study in acetonitrile.

  Annali di chimica 20020301

• [Study on the effect of Rhizoma Curcuma Longa on gastrin receptor].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20020301

• Curcumin induces apoptosis in human breast cancer cells through p53-dependent Bax induction.

  FEBS letters 20020213

• Sensitive markers used to identify compounds that trigger apoptosis in cultured hepatocytes.

  Toxicological sciences : an official journal of the Society of Toxicology 20020201

• Pre-clinical and early-phase clinical studies of curcumin as chemopreventive agent for endemic cancers in Taiwan.

  Gan to kagaku ryoho. Cancer & chemotherapy 20020201

• Curcumin (diferuloylmethane) induces apoptosis through activation of caspase-8, BID cleavage and cytochrome c release: its suppression by ectopic expression of Bcl-2 and Bcl-xl.

  Carcinogenesis 20020101

• Prevention of radiation-induced mammary tumors.

  International journal of radiation oncology, biology, physics 20020101

• Metabolism of the cancer chemopreventive agent curcumin in human and rat intestine.

  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20020101

• Leishmanicidal effect of curcumin in vitro.

  Biological & pharmaceutical bulletin 20020101

• Curcumin inhibits collagen synthesis and hepatic stellate cell activation in-vivo and in-vitro.

  The Journal of pharmacy and pharmacology 20020101

• Efficacy of turmeric on blood sugar and polyol pathway in diabetic albino rats.

  Plant foods for human nutrition (Dordrecht, Netherlands) 20020101

• Synthetic derivatives of curcumin and their activity against Leishmania amazonensis.

  Arzneimittel-Forschung 20020101

• Inhibition of human low density lipoprotein oxidation by active principles from spices.

  Molecular and cellular biochemistry 20020101

• Curcumin: a new cell-permeant inhibitor of the inositol 1,4,5-trisphosphate receptor.

  Cell calcium 20020101

• Chemotherapeutic potential of curcumin for colorectal cancer.

  Current pharmaceutical design 20020101

• Inhibition of mouse skin tumor promotion by anti-inflammatory diarylheptanoids derived from Alpinia oxyphylla Miquel (Zingiberaceae).

  Oncology research 20020101

• Total synthesis and anti-leishmanial activity of some curcumin analogues.

  Arzneimittel-Forschung 20020101

• The protective effects of tetrahydrocurcumin on oxidative stress in cholesterol-fed rabbits.

  Journal of atherosclerosis and thrombosis 20020101

• Evaluation of antioxidant activities and antimutagenicity of turmeric oil: a byproduct from curcumin production.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20020101

• Effect of different curcumin dosages on human gall bladder.

  Asia Pacific journal of clinical nutrition 20020101

• Curcumin differentially regulates TGF-beta1, its receptors and nitric oxide synthase during impaired wound healing.

  BioFactors (Oxford, England) 20020101

• Turmeric (Curcuma longa) and curcumin inhibit the growth of Helicobacter pylori, a group 1 carcinogen.

  Anticancer research 20020101

• The experimental and clinical study on the effect of curcumin on cell cycle proteins and regulating proteins of apoptosis in acute myelogenous leukemia.

  Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20020101

• c-Jun N-terminal kinase is involved in motility of endothelial cell.

  Experimental & molecular medicine 20011231

• Curcumin, a molecule that inhibits the Ca2+-ATPase of sarcoplasmic reticulum but increases the rate of accumulation of Ca2+.

  The Journal of biological chemistry 20011214

• Curcumin induces apoptosis in human melanoma cells through a Fas receptor/caspase-8 pathway independent of p53.

  Experimental cell research 20011210

• Regulation of pro-inflammatory cytokine expression by curcumin in hyaline membrane disease (HMD).

  Life sciences 20011207

• Inhibition of the SERCA Ca2+ pumps by curcumin. Curcumin putatively stabilizes the interaction between the nucleotide-binding and phosphorylation domains in the absence of ATP.

  European journal of biochemistry 20011201

• Diarylheptanoids with free radical scavenging and hepatoprotective activity in vitro from Curcuma longa.

  Planta medica 20011201

• Clinical development of leukocyte cyclooxygenase 2 activity as a systemic biomarker for cancer chemopreventive agents.

  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20011201

• A laser flash photolysis study of curcumin in dioxane-water mixtures.

  Photochemistry and photobiology 20011201

• Modulation of radiation-induced protein kinase C activity by phenolics.

  Journal of radiological protection : official journal of the Society for Radiological Protection 20011201

• Curcumin downregulates cell survival mechanisms in human prostate cancer cell lines.

  Oncogene 20011115

• Mechanisms of curcumin-induced apoptosis of Ehrlich's ascites carcinoma cells.

  Biochemical and biophysical research communications 20011102

• Mechanism of heme oxygenase-1 gene induction by curcumin in human renal proximal tubule cells.

  American journal of physiology. Renal physiology 20011101

• The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20011101

• Curcumin, a medicinal herbal compound capable of inducing the heat shock response.

  Critical care medicine 20011101

• Curcumin: a heat shock response inducer and potential cytoprotector.

  Critical care medicine 20011101

• Protective effects of curcumin against oxidative damage on skin cells in vitro: its implication for wound healing.

  The Journal of trauma 20011101

• Signal transduction system for interleukin-6 synthesis stimulated by lipopolysaccharide in human osteoblasts.

  Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20011101

• Specific inhibition of cyclooxygenase-2 (COX-2) expression by dietary curcumin in HT-29 human colon cancer cells.

  Cancer letters 20011030

• Curcumin prevents intravesical tumor implantation of the MBT-2 tumor cell line in C3H mice.

  The Journal of urology 20011001

• NF-kappaB and the MAP kinases/AP-1 pathways are both involved in interleukin-6 and interleukin-8 expression in fibroblast-like synoviocytes stimulated by protein I/II, a modulin from oral streptococci.

  Cellular microbiology 20011001

• Induction of stress response renders human tumor cell lines resistant to curcumin-mediated apoptosis: role of reactive oxygen intermediates.

  Cell stress & chaperones 20011001

• Total synthesis of Calebin-A, preparation of its analogues, and their neuronal cell protectivity against beta-amyloid insult.

  Bioorganic & medicinal chemistry letters 20010917

• Curcumin inhibits activation of Vgamma9Vdelta2 T cells by phosphoantigens and induces apoptosis involving apoptosis-inducing factor and large scale DNA fragmentation.

  Journal of immunology (Baltimore, Md. : 1950) 20010915

• Caspase-dependent cleavage of ErbB-2 by geldanamycin and staurosporin.

  The Journal of biological chemistry 20010907

• Effect of glutathione depletion on caspase-3 independent apoptosis pathway induced by curcumin in Jurkat cells.

  Free radical biology & medicine 20010901

• Quercetin and curcumin up-regulate antioxidant gene expression in rat kidney after ureteral obstruction or ischemia/reperfusion injury.

  Transplantation proceedings 20010901

• Occurrence of ochratoxin A in black pepper, coriander, ginger and turmeric in India.

  Food additives and contaminants 20010901

• Curcuma longa (turmeric). Monograph.

  Alternative medicine review : a journal of clinical therapeutic 20010901

• Curcumin-induced differentiation of mouse embryonal carcinoma PCC4 cells.

  Differentiation; research in biological diversity 20010901

• [Study on active constituents of traditional Chinese medicine reversing multidrug resistance of tumor cells in vitro].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20010901

• Protection of radiation-induced protein damage by curcumin.

  Biophysical chemistry 20010830

• The use of a high-volume screening procedure to assess the effects of dietary flavonoids on human cyp1a1 expression.

  Drug metabolism and disposition: the biological fate of chemicals 20010801

• Regulation of ANP clearance receptors by EGF in mesangial cells from NOD mice.

  American journal of physiology. Renal physiology 20010801

• A curcuminoid and sesquiterpenes as inhibitors of macrophage TNF-alpha release from Curcuma zedoaria.

  Planta medica 20010801

• HIV-1 integrase inhibitory phenylpropanoid glycosides from Clerodendron trichotomum.

  Archives of pharmacal research 20010801

• Inhibition of invasion and induction of apoptosis by curcumin in H-ras-transformed MCF10A human breast epithelial cells.

  Archives of pharmacal research 20010801

• Pharmacodynamic and pharmacokinetic study of oral Curcuma extract in patients with colorectal cancer.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20010701

• Mechanistic studies on the inhibitory action of dietary dibenzoylmethane, a beta-diketone analogue of curcumin, on 7,12-dimethylbenz[a]anthracene-induced mammary tumorigenesis.

  Proceedings of the National Science Council, Republic of China. Part B, Life sciences 20010701

• Biological activities of Curcuma longa L.

  Memorias do Instituto Oswaldo Cruz 20010701

• Role of glutathione S-transferase P1, P-glycoprotein and multidrug resistance-associated protein 1 in acquired doxorubicin resistance.

  International journal of cancer 20010615

• Differential regulation of apoptosis in AK-5 tumor cells by the proto-oncogene Bcl-2: presence of Bcl-2 dependent and independent pathways.

  FEBS letters 20010615

• Curcumin, a natural product present in turmeric, decreases tumor growth but does not behave as an anticachectic compound in a rat model.

  Cancer letters 20010610

• Inhibition of cytochrome P450 isozymes by curcumins in vitro and in vivo.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20010601

• Therapeutic potential of curcumin in human prostate cancer. III. Curcumin inhibits proliferation, induces apoptosis, and inhibits angiogenesis of LNCaP prostate cancer cells in vivo.

  The Prostate 20010601

• Disparate effects of similar phenolic phytochemicals as inhibitors of oxidative damage to cellular DNA.

  Mutation research 20010510

• Unusually large numbers of electrons for the oxidation of polyphenolic antioxidants.

  Biochimica et biophysica acta 20010503

• Curcumin modifies Apc(min) apoptosis resistance and inhibits 2-amino 1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) induced tumour formation in Apc(min) mice.

  Carcinogenesis 20010501

• Effects of dietary curcumin on glutathione S-transferase and malondialdehyde-DNA adducts in rat liver and colon mucosa: relationship with drug levels.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20010501

• Chemical studies on antioxidant mechanism of curcumin: analysis of oxidative coupling products from curcumin and linoleate.

  Journal of agricultural and food chemistry 20010501

• Curcuminoids from Curcuma longa L. (Zingiberaceae) that protect PC12 rat pheochromocytoma and normal human umbilical vein endothelial cells from betaA(1-42) insult.

  Neuroscience letters 20010427

• Cytoprotective effect of curcumin in human proximal tubule epithelial cells exposed to shiga toxin.

  Biochemical and biophysical research communications 20010427

• Curcumin induces the mitochondrial permeability transition pore mediated by membrane protein thiol oxidation.

  FEBS letters 20010420

• How curcumin works preferentially with water soluble antioxidants.

  Journal of the American Chemical Society 20010404

• Inhibitors of human immunodeficiency virus type 1 reverse transcriptase target distinct phases of early reverse transcription.

  Journal of virology 20010401

• Synergistic induction of apoptosis in human leukemia cells (U937) exposed to bryostatin 1 and the proteasome inhibitor lactacystin involves dysregulation of the PKC/MAPK cascade.

  Blood 20010401

• Effect of ultraviolet A on ornithine decarboxylase and metallothionein gene expression in mouse skin.

  Photodermatology, photoimmunology & photomedicine 20010401

• Mechanisms of cancer chemoprevention by curcumin.

  Proceedings of the National Science Council, Republic of China. Part B, Life sciences 20010401

• Growth suppression of hamster flank organs by topical application of catechins, alizarin, curcumin, and myristoleic acid.

  Archives of dermatological research 20010401

• Is the effect of interleukin-1 on glutathione oxidation in cultured human fibroblasts involved in nuclear factor-kappaB activation?

  Antioxidants & redox signaling 20010401

• Oncostatin M-induced matrix metalloproteinase and tissue inhibitor of metalloproteinase-3 genes expression in chondrocytes requires Janus kinase/STAT signaling pathway.

  Journal of immunology (Baltimore, Md. : 1950) 20010301

• Lack of chemopreventive effects of lycopene and curcumin on experimental rat prostate carcinogenesis.

  Carcinogenesis 20010301

• Induction of apoptosis by garcinol and curcumin through cytochrome c release and activation of caspases in human leukemia HL-60 cells.

  Journal of agricultural and food chemistry 20010301

• Alternative activation of extracellular signal-regulated protein kinases in curcumin and arsenite-induced HSP70 gene expression in human colorectal carcinoma cells.

  European journal of cell biology 20010301

• Signal transduction system for interleukin-6 and interleukin-11 synthesis stimulated by epinephrine in human osteoblasts and human osteogenic sarcoma cells.

  Biochemical pharmacology 20010201

• Characterization of metabolites of the chemopreventive agent curcumin in human and rat hepatocytes and in the rat in vivo, and evaluation of their ability to inhibit phorbol ester-induced prostaglandin E2 production.

  Cancer research 20010201

• Effects of the antioxidants curcumin or selenium on cisplatin-induced nephrotoxicity and lipid peroxidation in rats.

  Pharmacological research 20010201

• Involvement of glutathione metabolism in the cytotoxicity of the phenethyl isothiocyanate and its cysteine conjugate to human leukaemia cells in vitro.

  Biochemical pharmacology 20010115

• Effects of turmeric on the activities of benzo(a)pyrene-induced cytochrome P-450 isozymes.

  Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20010101

• Protective effect of thiourea, a hydroxyl-radical scavenger, on curcumin-induced chromosomal aberrations in an in vitro mammalian cell system.

  Teratogenesis, carcinogenesis, and mutagenesis 20010101

• Antioxidants in chemoprevention of skin cancer.

  Current problems in dermatology 20010101

• Inhibition of carcinogen induced c-Ha-ras and c-fos proto-oncogenes expression by dietary curcumin.

  BMC cancer 20010101

• Curcumin induced modulation of cell cycle and apoptosis in gastric and colon cancer cells.

  Anticancer research 20010101

• Syntheses of Curcumin Bioconjugates and Study of Their Antibacterial Activities against beta-Lactamase-Producing Microorganisms.

  Bioconjugate chemistry 20010101

• Potential role of antioxidants during ethanol-induced changes in the fatty acid composition and arachidonic acid metabolites in male Wistar rats.

  Cell biology and toxicology 20010101

• Phase I clinical trial of curcumin, a chemopreventive agent, in patients with high-risk or pre-malignant lesions.

  Anticancer research 20010101

• Phenolic anti-inflammatory antioxidant reversal of Abeta-induced cognitive deficits and neuropathology.

  Neurobiology of aging 20010101

• Chemopreventive effects of curcumin on glandular stomach carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine and sodium chloride in rats.

  Anticancer research 20010101

• Study on curcumin-oligonucleotide conjugate as a probable anticancer agent: its hybridisation with telomere target sequence 5'-GGGATTGGGATT-3'.

  Nucleic acids research. Supplement (2001) 20010101

• Spontaneous shift in transcriptional profile of explanted glomeruli via activation of the MAP kinase family.

  American journal of physiology. Renal physiology 20001101

• Arsenite induces apoptosis of murine T lymphocytes through membrane raft-linked signaling for activation of c-Jun amino-terminal kinase.

  Journal of immunology (Baltimore, Md. : 1950) 20001015

• Anti-apoptotic effect of quercetin: intervention in the JNK- and ERK-mediated apoptotic pathways.

  Kidney international 20000901

• Synthesis and HIV-1 integrase inhibitory activities of caffeoylglucosides.

  Bioorganic & medicinal chemistry letters 20000821

• Modulation of apoptotic and inflammatory genes by bioflavonoids and angiotensin II inhibition in ureteral obstruction.

  Urology 20000801

• Therapeutic potential of curcumin in human prostate cancer-I. curcumin induces apoptosis in both androgen-dependent and androgen-independent prostate cancer cells.

  Prostate cancer and prostatic diseases 20000801

• Steroid hormone activity of flavonoids and related compounds.

  Breast cancer research and treatment 20000701

• Plant phenolics decrease intestinal tumors in an animal model of familial adenomatous polyposis.

  Carcinogenesis 20000501

• The effect of mycophenolate mofetil and polyphenolic bioflavonoids on renal ischemia reperfusion injury and repair.

  The Journal of urology 20000301

• Pulmonary protective effects of curcumin against paraquat toxicity.

  Life sciences 20000101

• Curcumin prevents adriamycin nephrotoxicity in rats.

  British journal of pharmacology 20000101

• Therapeutic potential of curcumin in human prostate cancer. II. Curcumin inhibits tyrosine kinase activity of epidermal growth factor receptor and depletes the protein.

  Molecular urology 20000101

• Oral administration of a turmeric extract inhibits LDL oxidation and has hypocholesterolemic effects in rabbits with experimental atherosclerosis.

  Atherosclerosis 19991201

• The effect of curcumin on glutathione-linked enzymes in K562 human leukemia cells.

  Toxicology letters 19990920

• Effects of Curcuma Longa on proliferation of cultured bovine smooth muscle cells and on expression of low density lipoprotein receptor in cells.

  Chinese medical journal 19990401

• Geometrically and conformationally restrained cinnamoyl compounds as inhibitors of HIV-1 integrase: synthesis, biological evaluation, and molecular modeling.

  Journal of medicinal chemistry 19981008

• Stimulation of the stress-induced expression of stress proteins by curcumin in cultured cells and in rat tissues in vivo.

  Cell stress & chaperones 19980901

• Curcumin attenuation of acute adriamycin myocardial toxicity in rats.

  British journal of pharmacology 19980601

• Protective effect of turmeric (Curcuma longa L.) extract on carbon tetrachloride-induced liver damage in rats.

  Indian journal of experimental biology 19980601

• Subchronic oral toxicity of turmeric and ethanolic turmeric extract in female mice and rats.

  Toxicology letters 19980501

• Chemopreventive efficacy of curcumin-free aqueous turmeric extract in 7,12-dimethylbenz[a]anthracene-induced rat mammary tumorigenesis.

  Cancer letters 19980116

• Curcumin and curcumin derivatives inhibit Tat-mediated transactivation of type 1 human immunodeficiency virus long terminal repeat.

  Research in virology 19980101

• Retardation of experimental tumorigenesis and reduction in DNA adducts by turmeric and curcumin.

  Nutrition and cancer 19980101

• Interactions of alpha, beta-unsaturated aldehydes and ketones with human glutathione S-transferase P1-1.

  Chemico-biological interactions 19971212

• Inhibitory effects of curcumin-free aqueous turmeric extract on benzo[a]pyrene-induced forestomach papillomas in mice.

  Cancer letters 19970916

• Curcumin analogs with altered potencies against HIV-1 integrase as probes for biochemical mechanisms of drug action.

  Journal of medicinal chemistry 19970912

• Effect of turmeric oil and turmeric oleoresin on cytogenetic damage in patients suffering from oral submucous fibrosis.

  Cancer letters 19970624

• Arylamide inhibitors of HIV-1 integrase.

  Journal of medicinal chemistry 19970411

• Effects of n-tritriacontane-16,18-dione, curcumin, chlorphyllin, dihydroguaiaretic acid, tannic acid and phytic acid on the initiation stage in a rat multi-organ carcinogenesis model.

  Cancer letters 19970226

• Synergistic effects of curcumin on all-trans retinoic acid- and 1 alpha,25-dihydroxyvitamin D3-induced differentiation in human promyelocytic leukemia HL-60 cells.

  Oncology research 19970101

• Transcriptional regulation by transforming growth factor beta of the expression of retinoic acid and retinoid X receptor genes in osteoblastic cells is mediated through AP-1.

  The Journal of biological chemistry 19961206

• Inhibition of HIV-1 Tat-mediated transactivation by quinacrine and chloroquine.

  Biochemical and biophysical research communications 19960904

• Differential inhibition of HIV-1 preintegration complexes and purified integrase protein by small molecules.

  Proceedings of the National Academy of Sciences of the United States of America 19960903

• Effect of curcumin on certain lysosomal hydrolases in isoproterenol-induced myocardial infarction in rats.

  Biochemical pharmacology 19960112

• Antifungal activity of turmeric oil extracted from Curcuma longa (Zingiberaceae).

  Journal of ethnopharmacology 19951215

• Inhibition of human immunodeficiency virus type-1 integrase by curcumin.

  Biochemical pharmacology 19950418

• Curcumin, an anti-tumour promoter and anti-inflammatory agent, inhibits induction of nitric oxide synthase in activated macrophages.

  Biochemical and biophysical research communications 19950117

• Three inhibitors of type 1 human immunodeficiency virus long terminal repeat-directed gene expression and virus replication.

  Proceedings of the National Academy of Sciences of the United States of America 19930301

• Reversal of aflatoxin induced liver damage by turmeric and curcumin.

  Cancer letters 19920930

• Protective role of aqueous turmeric extract against mutagenicity of direct-acting carcinogens as well as benzo [alpha] pyrene-induced genotoxicity and carcinogenicity.

  Journal of cancer research and clinical oncology 19920101

• Pharmacology of Curcuma longa.

  Planta medica 19910201

• Evaluation of turmeric (Curcuma longa) for gastric and duodenal antiulcer activity in rats.

  Journal of ethnopharmacology 19900401

• Sister chromatid exchange and chromosome aberrations induced by curcumin and tartrazine on mammalian cells in vivo.

  Cytobios 19900101

• Turmeric and curcumin as topical agents in cancer therapy.

  Tumori 19870227

• Potential anticancer activity of turmeric (Curcuma longa).

  Cancer letters 19851101