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Synthesis and antiviral activity of novel HCV NS3 protease inhibitors with P4 capping groups.
Bioorganic & medicinal chemistry letters 20121215
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Design, synthesis and antibacterial activity of minor groove binders: the role of non-cationic tail groups.
European journal of medicinal chemistry 20121001
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Synthesis and biological evaluation of cyanoguanidine derivatives of loratadine.
Bioorganic & medicinal chemistry letters 20121001
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Poly[bis-(1-carbamoylguanidinium) [tri-μ-chlorido-dichloridobismuthate(III)]].
Acta crystallographica. Section E, Structure reports online 20120501
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Alkoxy-1,3,5-triazapentadien(e/ato) copper(II) complexes: template formation and applications for the preparation of pyrimidines and as catalysts for oxidation of alcohols to carbonyl products.
Chemistry (Weinheim an der Bergstrasse, Germany) 20120116
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A liquid chromatography-tandem mass spectrometry method for the detection of economically motivated adulteration in protein-containing foods.
Journal of chromatography. A 20120113
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Tris(2-carbamoylguanidinium) hydrogen fluoro-phospho-nate fluoro-phospho-nate monohydrate.
Acta crystallographica. Section E, Structure reports online 20120101
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[Effects of nitrification inhibitors DCD and DMPP on cinnamon soil' s gross nitrogen mineralization and nitrification rates].
Ying yong sheng tai xue bao = The journal of applied ecology 20120101
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Synthesis and histamine H(3) and H(4) receptor activity of conformationally restricted cyanoguanidines related to UR-PI376.
Archiv der Pharmazie 20111201
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Aging impairs vasodilatory responses in rats.
Korean journal of anesthesiology 20111201
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2-(1,3-Benzothia-zol-2-yl)guanidinium chloride.
Acta crystallographica. Section E, Structure reports online 20111101
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[Mitigation of nitrous oxide emissions in vegetable system by treating soil with dicyandiamide, a nitrification inhibitor].
Huan jing ke xue= Huanjing kexue 20111101
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Direct synthesis of nanoporous carbon nitride fibers using Al-based porous coordination polymers (Al-PCPs).
Chemical communications (Cambridge, England) 20110728
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Thiourea isosteres as anion receptors and transmembrane transporters.
Chemical communications (Cambridge, England) 20110721
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Antitumor effect of BPR-DC-2, a novel synthetic cyclic cyanoguanidine derivative, involving the inhibition of MDR-1 expression and down-regulation of p-AKT and PARP-1 in lung cancer.
Investigational new drugs 20110401
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Complexes of copper(II) with 3-(ortho-substituted phenylhydrazo)pentane-2,4-diones: syntheses, properties and catalytic activity for cyclohexane oxidation.
Dalton transactions (Cambridge, England : 2003) 20110328
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Novel chelating resin with cyanoguanidine group: useful recyclable materials for Hg(II) removal in aqueous environment.
Journal of hazardous materials 20110130
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The resistance of the yeast Saccharomyces cerevisiae to the biocide polyhexamethylene biguanide: involvement of cell wall integrity pathway and emerging role for YAP1.
BMC molecular biology 20110101
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Histamine H4 receptor agonists.
Bioorganic & medicinal chemistry letters 20101215
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Effect of cattle slurry pre-treatment by separation and addition of nitrification inhibitors on gaseous emissions and N dynamics: a laboratory study.
Chemosphere 20100401
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Nanoparticulate Quillaja saponin induces apoptosis in human leukemia cell lines with a high therapeutic index.
International journal of nanomedicine 20100101
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Partial purification and characterization of the mode of action of enterocin S37: a bacteriocin produced by Enterococcus faecalis S37 isolated from poultry feces.
Journal of environmental and public health 20100101
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Target enzyme mutations are the molecular basis for resistance towards pharmacological inhibition of nicotinamide phosphoribosyltransferase.
BMC cancer 20100101
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Determination of impurities in medical products containing metformin hydrochloride.
Acta poloniae pharmaceutica 20100101
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Bis(1-carbamimidoyl-2-ethyl-isourea)copper(II) dinitrate.
Acta crystallographica. Section E, Structure reports online 20091101
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Synthesis and structure-activity relationships of cyanoguanidine-type and structurally related histamine H4 receptor agonists.
Journal of medicinal chemistry 20091022
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Development and validation of an analytical method for metformin hydrochloride and its related compound (1-cyanoguanidine) in tablet formulations by HPLC-UV.
Talanta 20091015
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Bis(1-carbamimidoyl-2-ethyl-isourea)copper(II) bis-(perchlorate).
Acta crystallographica. Section E, Structure reports online 20091001
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Different routes for amination of platinum(II)-bound cyanoguanidine.
Inorganic chemistry 20090921
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Cyanoguanidine-based lactam derivatives as a novel class of orally bioavailable factor Xa inhibitors.
Bioorganic & medicinal chemistry letters 20090801
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Modulatory action of potassium channel openers on field potential and histamine release from rat peritoneal mast cells.
Canadian journal of physiology and pharmacology 20090801
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Purinergic P2X(7) receptor antagonists: Chemistry and fundamentals of biological screening.
Bioorganic & medicinal chemistry 20090715
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Effect of timing of joint application of hydroquinone and dicyandiamide on nitrous oxide emission from irrigated lowland rice paddy field.
Chemosphere 20090601
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Bis[diamino-(ethoxy-carbonyl-amino)-methyl-ium] sulfate.
Acta crystallographica. Section E, Structure reports online 20090401
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Selective P2X(7) receptor antagonists for chronic inflammation and pain.
Purinergic signalling 20090301
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The use of microelectrode array (MEA) to study the protective effects of potassium channel openers on metabolically compromised HL-1 cardiomyocytes.
Physiological measurement 20090201
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Regression of orthotopic neuroblastoma in mice by targeting the endothelial and tumor cell compartments.
Journal of translational medicine 20090101
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Structure-activity relationship analysis of cytotoxic cyanoguanidines: selection of CHS 828 as candidate drug.
BMC research notes 20090101
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Synthesis and activity of N-cyanoguanidine-piperazine P2X7 antagonists.
Bioorganic & medicinal chemistry letters 20080715
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Attenuation of N2O emission rates from agricultural soil at different dicyandiamide concentrations.
Environmental monitoring and assessment 20080201
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Structure-activity studies of novel cyanoguanidine ATP-sensitive potassium channel openers for the treatment of overactive bladder.
Journal of medicinal chemistry 20071129
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Design, synthesis, and SAR study of a series of N-alkyl-N'-[2-(aryloxy)-5-nitrobenzenesulfonyl]ureas and -cyanoguanidine as selective antagonists of the TPalpha and TPbeta isoforms of the human thromboxane A2 receptor.
Journal of medicinal chemistry 20070809
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Novel P2X7 receptor antagonists ease the pain.
British journal of pharmacology 20070701
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Overactive bladder treatments in early phase clinical trials.
Expert opinion on investigational drugs 20070701
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Molecular structure, bioavailability and bioactivity of [Cu(o-phen)2(cnge)](NO3)2.2H2O and [Cu(o-phen)(cnge)(H2O)(NO3)2] complexes.
Journal of inorganic biochemistry 20070501
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Biodegradability of end-groups of the biocide polyhexamethylene biguanide (PHMB) assessed using model compounds.
Journal of industrial microbiology & biotechnology 20060801
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[Effects of nitrification inhibitors on nitrate content in soil and pakchoi and on pakchoi yield].
Ying yong sheng tai xue bao = The journal of applied ecology 20060201
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Structure-activity relationships of K(ATP) channel openers.
Current topics in medicinal chemistry 20060101
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Identification of molecular mechanisms for cellular drug resistance by combining drug activity and gene expression profiles.
British journal of cancer 20050822
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[HPLC determination of metformin hydrochloride-related substances].
Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20050701
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Effects of slow-release urea fertilizers on urease activity, microbial biomass, and nematode communities in an aquic brown soil.
Science in China. Series C, Life sciences 20050501
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Quantitative structure-activity relationship by CoMFA for cyclic urea and nonpeptide-cyclic cyanoguanidine derivatives on wild type and mutant HIV-1 protease.
Journal of molecular modeling 20050301
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Neuroprotective effect of KR-31378, a novel potassium channel activator, on spinal cord ischemic injury in rabbits.
Journal of investigative surgery : the official journal of the Academy of Surgical Research 20050101
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Antitumoural effects of the pyridyl cyanoguanidine CHS 828 on three different types of neuroendocrine tumours xenografted to nude mice.
Neuroendocrinology 20050101
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Effect of two amino acids in TM17 of Sulfonylurea receptor SUR1 on the binding of ATP-sensitive K+ channel modulators.
Diabetes 20041201
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Novel glycine transporter type-2 reuptake inhibitors. Part 2: beta- and gamma-amino acid derivatives.
Bioorganic & medicinal chemistry 20040815
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Arylcyanoguanidines as activators of Kir6.2/SUR1K ATP channels and inhibitors of insulin release.
Journal of medicinal chemistry 20040603
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Hypotonic stress increases efficacy of rilmakalim, but not pinacidil, to activate ATP-sensitive K(+) current in guinea pig ventricular myocytes.
Journal of pharmacological sciences 20040601
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Multiparametric evaluation of apoptosis: effects of standard cytotoxic agents and the cyanoguanidine CHS 828.
Molecular cancer therapeutics 20040501
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Interaction of a novel dihydropyridine K+ channel opener, A-312110, with recombinant sulphonylurea receptors and KATP channels: comparison with the cyanoguanidine P1075.
British journal of pharmacology 20040401
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Design, synthesis, and biological evaluation of thio-containing compounds with serum HDL-cholesterol-elevating properties.
Journal of medicinal chemistry 20040129
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Design and synthesis of novel cyanoguanidine ATP-sensitive potassium channel openers for the treatment of overactive bladder.
Bioorganic & medicinal chemistry letters 20040119
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Dihydropyridine neuropeptide Y Y1 receptor antagonists 2. bioisosteric urea replacements.
Bioorganic & medicinal chemistry 20040115
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Development and characterization of two human tumor sublines expressing high-grade resistance to the cyanoguanidine CHS 828.
Anti-cancer drugs 20040101
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Dicyandiamide and 3,4-dimethyl pyrazole phosphate decrease N2O emissions from grassland but dicyandiamide produces deleterious effects in clover.
Journal of plant physiology 20031201
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A selective human H(4)-receptor agonist: (-)-2-cyano-1-methyl-3-[(2R,5R)-5- [1H-imidazol-4(5)-yl]tetrahydrofuran-2-y] methylguanidine.
Journal of medicinal chemistry 20030703
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Bis(cyanoguanidine)silver(I) nitrate-cyanoguanidine (1/1).
Acta crystallographica. Section C, Crystal structure communications 20030601
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Synthesis and biological activity of 3,3-diamino-sulfonylacrylonitriles as novel inhibitors of glucose induced insulin secretion from beta cells.
Bioorganic & medicinal chemistry 20030320
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A pharmacophore model for sulphonyl-urea (-cyanoguanidine) compounds with dual action, thromboxane receptor antagonists and thromboxane synthase inhibitors.
European journal of medicinal chemistry 20030101
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Activation of p53 protein in normal and in tumor cells by a novel anticancer agent CHS 828.
Drugs under experimental and clinical research 20030101
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The stereoenantiomers of a pinacidil analog open or close cloned ATP-sensitive K+ channels.
The Journal of biological chemistry 20021025
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The combination of the antitumoural pyridyl cyanoguanidine CHS 828 and etoposide in vitro--from cytotoxic synergy to complete inhibition of apoptosis.
British journal of pharmacology 20021001
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Potent and selective inhibitors of PDGF receptor phosphorylation. 2. Synthesis, structure activity relationship, improvement of aqueous solubility, and biological effects of 4-[4-(N-substituted (thio)carbamoyl)-1-piperazinyl]-6,7-dimethoxyquinazoline derivatives.
Journal of medicinal chemistry 20020926
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Structure-activity relationship of linear peptide Bu-His-DPhe-Arg-Trp-Gly-NH(2) at the human melanocortin-1 and -4 receptors: arginine substitution.
Bioorganic & medicinal chemistry letters 20020902
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Interactions between the new cytotoxic drug CHS 828 and amiloride and mitomycin C in a human tumour cell line and in tumour cells from patients.
Chemotherapy 20020901
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A Phase I study of CHS 828 in patients with solid tumor malignancy.
Clinical cancer research : an official journal of the American Association for Cancer Research 20020901
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Emission of nitrous oxide from rice-wheat systems of Indo-Gangetic plains of India.
Environmental monitoring and assessment 20020701
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Hydrophobic similarity between molecules: a MST-based hydrophobic similarity index.
Journal of computational chemistry 20020415
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Modulation of pyridyl cyanoguanidine (CHS 828) induced cytotoxicity by 3-aminobenzamide in U-937 GTB cells.
Biochemical pharmacology 20020415
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Tricyclic cyanoguanidines: synthesis, site of action and insecticidal activity of a novel class of reversible acetylcholinesterase inhibitors.
Bioorganic & medicinal chemistry 20020301
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Synthesis of 5,6-dihydro-11H-benzo[5,6]-cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidine-N-cyanoguanidine derivatives as inhibitors of ras farnesyl protein transferase.
Bioorganic & medicinal chemistry letters 20020225
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A novel anti-ischemic ATP-sensitive potassium channel (K(ATP)) opener without vasorelaxation: N-(6-aminobenzopyranyl)-N'-benzyl-N' '-cyanoguanidine analogue.
Journal of medicinal chemistry 20011122
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Human beta3 adrenergic receptor agonists containing cyanoguanidine and nitroethylenediamine moieties.
Bioorganic & medicinal chemistry letters 20010212
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A hollow fiber model for in vitro studies of cytotoxic compounds: activity of the cyanoguanidine CHS 828.
Anti-cancer drugs 20010101
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A modified spray reagent for the detection of amino acids on thin layer chromatography plates.
Amino acids 20010101
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Occupational allergic contact dermatitis caused by 2,4,6-tris-(dimethylaminomethyl)phenol, and review of sensitizing epoxy resin hardeners.
International journal of dermatology 19961201
