461-82-5 | 4-(Trifluoromethoxy)aniline

Packsize	Purity	Availability	Price	Discounted Price
5g	98%	in stock	$22.00	$15.00
25g	98%	in stock	$41.00	$29.00
100g	98%	in stock	$89.00	$62.00
500g	98%	in stock	$249.00	$175.00

Description

• Catalog Number: AB44736
• Chemical Name: 4-(Trifluoromethoxy)aniline
• CAS Number: 461-82-5
• Molecular Formula: C7H6F3NO
• Molecular Weight: 177.1238
• MDL Number: MFCD00041314
• SMILES: FC(Oc1ccc(cc1)N)(F)F

Computed Properties

• Complexity: 140
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 12
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 1
• XLogP3: 2.2

Literature

• Triarylmethanes, a new class of cx50 inhibitors.

  Frontiers in pharmacology 20120101

• 2,5-Dimethyl-3-[4-(trifluoro-meth-oxy)anilino]-cyclo-hex-2-enone.

  Acta crystallographica. Section E, Structure reports online 20110301

• tert-Butyl 6-methyl-2-oxo-4-[4-(trifluoro-meth-oxy)anilino]cyclo-hex-3-ene-1-carboxyl-ate.

  Acta crystallographica. Section E, Structure reports online 20101201

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101

• Expanding the diversity of allosteric bcr-abl inhibitors.

  Journal of medicinal chemistry 20101014

• Synthesis of 1-(4-trifluoromethoxyphenyl)-2,5-dimethyl-3-(2-R-thiazol-4-yl)-1H-pyrroles via chain heterocyclization.

  Molecules (Basel, Switzerland) 20100223

• Trifluoromethoxy substituted anilines: metalation as the key step for structural elaboration.

  The Journal of organic chemistry 20030613

• The metabolism of 4-trifluoromethoxyaniline and [13C]-4-trifluoromethoxyacetanilide in the rat: detection and identification of metabolites excreted in the urine by NMR and HPLC-NMR.

  Journal of pharmaceutical and biomedical analysis 20020601