4621-66-3 | Thionicotinamide

Packsize	Purity	Availability	Price	Discounted Price
5g	98%	in stock	$14.00	$10.00
25g	98%	in stock	$38.00	$27.00
100g	98%	in stock	$110.00	$77.00
500g	98%	in stock	$511.00	$358.00

Description

• Catalog Number: AI50713
• Chemical Name: Thionicotinamide
• CAS Number: 4621-66-3
• Molecular Formula: C6H6N2S
• Molecular Weight: 138.1902
• MDL Number: MFCD00006399
• SMILES: NC(=S)c1cccnc1
• NSC Number: 18336

Computed Properties

• Complexity: 114
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 9
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 1
• XLogP3: 0.7

Literature

• Structural and kinetic isotope effect studies of nicotinamidase (Pnc1) from Saccharomyces cerevisiae.

  Biochemistry 20120110

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101

• Elucidating the structure-activity relationships of the vasorelaxation and antioxidation properties of thionicotinic acid derivatives.

  Molecules (Basel, Switzerland) 20100106

• 3-Carbamothioylpyridinium iodide.

  Acta crystallographica. Section E, Structure reports online 20091001

• Novel bUT-B2 urea transporter isoform is constitutively activated.

  American journal of physiology. Regulatory, integrative and comparative physiology 20090801

• Molecular cloning and characterization of a novel lactate dehydrogenase gene from Clonorchis sinensis.

  Parasitology research 20060601

• Electron transfer kinetics and mechanistic study of the thionicotinamide coordinated to the pentacyanoferrate(III)/(II) complexes: a model system for the in vitro activation of thioamides anti-tuberculosis drugs.

  Journal of inorganic biochemistry 20050201

• Urea transport in MDCK cells that are stably transfected with UT-A1.

  American journal of physiology. Cell physiology 20040601

• Interactions between transhydrogenase and thio-nicotinamide Analogues of NAD(H) and NADP(H) underline the importance of nucleotide conformational changes in coupling to proton translocation.

  The Journal of biological chemistry 20030829

• Structures of D-glyceraldehyde-3-phosphate dehydrogenase complexed with coenzyme analogues.

  Acta crystallographica. Section D, Biological crystallography 20020801

• [Chemical studies the mechanism of action of isoniazid].

  Arzneimittel-Forschung 19661101