464-43-7 | (+)-Borneol

Packsize	Purity	Availability	Price	Discounted Price
1g	95%	in stock	$52.00	$36.00

Description

• Catalog Number: AG24490
• Chemical Name: (+)-Borneol
• CAS Number: 464-43-7
• Molecular Formula: C10H18O
• Molecular Weight: 154.24932
• MDL Number: MFCD00066427
• SMILES: O[C@H]1C[C@@H]2C([C@@]1(C)CC2)(C)C

Computed Properties

• Complexity: 185
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 3
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 1
• Hydrogen Bond Donor Count: 1
• XLogP3: 2.7

Literature

• Toxicological role of an acyl glucuronide metabolite in diclofenac-induced acute liver injury in mice.

  Journal of applied toxicology : JAT 20170501

• In vivo effect of borneol on rat hepatic CYP2B expression and activity.

  Chemico-biological interactions 20170105

• Borneol Depresses P-Glycoprotein Function by a NF-κB Signaling Mediated Mechanism in a Blood Brain Barrier in Vitro Model.

  International journal of molecular sciences 20151101

• Effect of Xiongbing compound on the pharmacokinetics and brain targeting of tetramethylpyrazine.

  The Journal of pharmacy and pharmacology 20121101

• Borneol administration protects primary rat hepatocytes against exogenous oxidative DNA damage.

  Mutagenesis 20120901

• The effect of camphor and borneol on rat thymocyte viability and oxidative stress.

  Molecules (Basel, Switzerland) 20120827

• The effects of combined menthol and borneol on fluconazole permeation through the cornea ex vivo.

  European journal of pharmacology 20120805

• Velamo do campo: its volatile constituents, secretory elements, and biological activity.

  Journal of medicinal food 20120701

• Formation of β-cyclodextrin inclusion enhances the stability and aqueous solubility of natural borneol.

  Journal of food science 20120601

• Kinetics and mechanisms of the tropospheric reactions of menthol, borneol, fenchol, camphor, and fenchone with hydroxyl radicals (OH) and chlorine atoms (Cl).

  The journal of physical chemistry. A 20120426

• [Research of bornrol promote drugs through blood-brain barrier].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20120401

• Selective extraction of oxygenated compounds from oregano with sub-critical water.

  Journal of the science of food and agriculture 20120315

• Pharmacokinetics of natural borneol after oral administration in mice brain and its effect on excitation ratio.

  European journal of drug metabolism and pharmacokinetics 20120301

• Molecular metabolic fingerprinting approach to investigate the effects of borneol on metabolic alterations in the liver of nitric oxide deficient hypertensive rats.

  Molecular and cellular biochemistry 20120301

• Enhancing effects of different dosages of borneol on pharmacokinetics of salvanic acid B after oral administration to rats.

  Journal of Asian natural products research 20120101

• Preparation of natural borneol/2-hydroxypropyl-β-cyclodextrin inclusion complex and its effect on the absorption of tetramethylpyrazine phosphate in mouse.

  Chemical & pharmaceutical bulletin 20120101

• [Effects of penetration enhancers on curcumin transdermal drug delivery].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20120101

• Fumigant toxicity of lemon eucalyptus oil constituents to acaricide-susceptible and acaricide-resistant Tetranychus urticae.

  Pest management science 20111201

• Enhanced intestinal absorption of daidzein by borneol/menthol eutectic mixture and microemulsion.

  AAPS PharmSciTech 20111201

• [Volatile metabolites analysis and molecular identification of endophytic fungi bn12 from Cinnamomum camphora chvar. borneol].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20111201

• Chemical composition and antimicrobial activity of essential oils of Thymus algeriensis, Eucalyptus globulus and Rosmarinus officinalis from Morocco.

  Journal of the science of food and agriculture 20111101

• [Effect of single-used borneol and combining it with diazepam on content of neurotransmitter in corpus striatum of rats].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20111101

• MT103 inhibits tumor growth with minimal toxicity in murine model of lung carcinoma via induction of apoptosis.

  Investigational new drugs 20111001

• Novel irreversible small molecule inhibitors of replication protein A display single-agent activity and synergize with cisplatin.

  Molecular cancer therapeutics 20111001

• [Effect of electroacupuncture combined with intragastric administration of borneol on the permeability of blood-brain barrier in the mouse].

  Zhen ci yan jiu = Acupuncture research 20111001

• Pharmacokinetic study of borneol and menthol in rats after oral administration of qingyan drop pills.

  Planta medica 20110901

• Comparative pharmacokinetic and bioavailability studies of three salvianolic acids after the administration of Salviae miltiorrhizae alone or with synthetical borneol in rats.

  Fitoterapia 20110901

• Enhancement and mechanism of transdermal absorption of terpene-induced propranolol hydrochloride.

  Archives of pharmacal research 20110901

• [Study on rat nasal absorption in situ of borneol based on single pass perfusion method].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110901

• [Effects of aromatic resuscitation drugs on blood brain barrier in cerebral ischemia-reperfusion injury model rats].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110901

• A short-chain dehydrogenase involved in terpene metabolism from Zingiber zerumbet.

  The FEBS journal 20110801

• [Study on pharmacokinetics of borneol in rats injected with novel-xingnaojing by GC-FID].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110801

• Effects of borneol on the intestinal transport and absorption of two P-glycoprotein substrates in rats.

  Archives of pharmacal research 20110701

• Identification of camphor oxidation and reduction products in Pseudomonas putida: new activity of the cytochrome P450cam system.

  Journal of chemical ecology 20110601

• Protection by borneol on cortical neurons against oxygen-glucose deprivation/reperfusion: involvement of anti-oxidation and anti-inflammation through nuclear transcription factor κappaB signaling pathway.

  Neuroscience 20110310

• The distribution and expression of claudin-5 and occludin at the rat blood-optic nerve barrier after borneol treatment.

  Molecular biology reports 20110201

• Enhancing effect of natural borneol on the absorption of geniposide in rat via intranasal administration.

  Journal of Zhejiang University. Science. B 20110201

• Toxicological evaluation of acyl glucuronides of nonsteroidal anti-inflammatory drugs using human embryonic kidney 293 cells stably expressing human UDP-glucuronosyltransferase and human hepatocytes.

  Drug metabolism and disposition: the biological fate of chemicals 20110101

• [Intestinal absorption properties of three components in salvianolic acid extract and the effect of borneol on their absorption in rats].

  Yao xue xue bao = Acta pharmaceutica Sinica 20101201

• Impacts of bicyclo-monoterpene enhancers on transdermal delivery of ligustrazine.

  Yao xue xue bao = Acta pharmaceutica Sinica 20101101

• [Microdialysis and HPLC method for determination of concentration of pantoprazole in rat striatum aftercombined administration with borneol].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20101001

• Effect of borneol on the distribution of danshensu to the eye in rabbit via oral administration.

  Current eye research 20100701

• The orally combined neuroprotective effects of sodium ferulate and borneol against transient global ischaemia in C57 BL/6J mice.

  The Journal of pharmacy and pharmacology 20100701

• The in situ and in vivo study on enhancing effect of borneol in nasal absorption of Geniposide in rats.

  Archives of pharmacal research 20100501

• Pharmacokinetic interaction between puerarin and edaravone, and effect of borneol on the brain distribution kinetics of puerarin in rats.

  The Journal of pharmacy and pharmacology 20100301

• [Callus induction of Cinnamonum camphora and formation of borneol].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100301

• Stereoselective flunoxaprofen-S-acyl-glutathione thioester formation mediated by acyl-CoA formation in rat hepatocytes.

  Drug metabolism and disposition: the biological fate of chemicals 20100101

• Antimicrobial activity and essential oil composition of a new T. argyrophyllum (C. Koch) Tvzel var. argyrophyllum chemotype.

  Journal of oleo science 20100101

• Oral characteristics of bergenin and the effect of absorption enhancers in situ, in vitro and in vivo.

  Arzneimittel-Forschung 20100101

• Amidation of alcohols with nitriles under solvent-free conditions using molecular iodine as a catalyst.

  Journal of oleo science 20100101

• Investigation of the volatile fraction of rosemary infusion extracts.

  Scientia pharmaceutica 20100101

• [Study on antiinflammatory effect of different chemotype of Cinnamomum camphora on rat arthritis model induced by Freund's adjuvant].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20091201

• Investigation of sensory and volatile characteristics of farmed and wild barramundi (Lates calcarifer) using gas chromatography-olfactometry mass spectrometry and descriptive sensory analysis.

  Journal of agricultural and food chemistry 20091111

• Application of headspace solid phase microextraction for study of noncovalent interaction of borneol with human serum albumin.

  Acta pharmacologica Sinica 20091101

• Suppression of linalool acetate production in Lavandula x intermedia.

  Natural product communications 20091101

• Anti-Helicobacter pylori activity and essential oil composition of Thymus caramanicus from Iran.

  Natural product communications 20090801

• [The enhancing effect of borneol on the absorption of tetramethylpyrazine].

  Yao xue xue bao = Acta pharmaceutica Sinica 20090801

• [Determination of d-borneol in the different parts of Cinnamomum camphora by GC-MS].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090701

• Effects of borneol on the level of DNA damage induced in primary rat hepatocytes and testicular cells by hydrogen peroxide.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090601

• Occurrence of dissolved and particle-bound taste and odor compounds in Swiss lake waters.

  Water research 20090501

• [Study on natural borneol and synthetic borneol affecting mucosal permeability of gardenia extract].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090501

• [Effects of borneol on pharmacokinetics of protocatechuic acid in rabbits].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090501

• Experimental and ab-initio calculated vcd spectra of the first OH-stretching overtone of (1R)-(-) and (1S)-(+)-endo-BORNEOL.

  Physical chemistry chemical physics : PCCP 20090421

• Essential oil composition of Artemisia herba-alba from southern Tunisia.

  Molecules (Basel, Switzerland) 20090420

• Determination of camphor and borneol in Flos Chrysanthemi Indici by UAE and GC-FID.

  Journal of chromatographic science 20090401

• Carvacrol is a novel inhibitor of Drosophila TRPL and mammalian TRPM7 channels.

  Cell calcium 20090301

• Influence of borneol on primary mice oral fibroblasts: a penetration enhancer may be used in oral submucous fibrosis.

  Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20090301

• [Effect of borneol/mentholum eutectic mixture on nasal-brain delivery of neurotoxin loaded nanoparticles].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090301

• Phytotoxicity of constituents of glandular trichomes and the leaf surface of camphorweed, Heterotheca subaxillaris.

  Phytochemistry 20090101

• Investigation of anti-oxidative, cytotoxic, DNA-damaging and DNA-protective effects of plant volatiles eugenol and borneol in human-derived HepG2, Caco-2 and VH10 cell lines.

  Mutation research 20090101

• Influence of borneol on in vitro corneal permeability and on in vivo and in vitro corneal toxicity.

  The Journal of international medical research 20090101

• NIR-VCD, vibrational circular dichroism in the near-infrared: experiments, theory and calculations.

  Chirality 20090101

• Fragrance material review on borneol.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20081101

• Fragrance material review on l-borneol.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20081101

• Fragrance material review on isoborneol.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20081101

• [Characterization of chemical components of essential oil from flowers of Chrysanthemum morifolium produced in Anhui province].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20081001

• Enantioselective formation of ibuprofen-S-acyl-glutathione in vitro in incubations of ibuprofen with rat hepatocytes.

  Chemical research in toxicology 20080901

• Identification and characterization of potent CYP2B6 inhibitors in Woohwangcheongsimwon suspension, an herbal preparation used in the treatment and prevention of apoplexy in Korea and China.

  Drug metabolism and disposition: the biological fate of chemicals 20080601

• ThermoTRP channels in nociceptors: taking a lead from capsaicin receptor TRPV1.

  Current neuropharmacology 20080301

• Herbal compounds and toxins modulating TRP channels.

  Current neuropharmacology 20080301

• Effect of borneol on the distribution of gastrodin to the brain in mice via oral administration.

  Journal of drug targeting 20080201

• [Influence of borneol on nasal absorption of Ligustrazinee].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080201

• Inhibition of 7,12-dimethylbenz[a]anthracene induced mouse skin carcinogenesis by Artemisia capillaris.

  Journal of food science 20080101

• Effects of borneol and thymoquinone on TNBS-induced colitis in mice.

  Folia biologica 20080101

• Molecular and cellular limits to somatosensory specificity.

  Molecular pain 20080101

• A simple gas chromatographic method for the simultaneous determination and pharmacokinetic study of tetramethylpyrazine phosphate and borneol in mouse plasma and brain tissue after oral administration of the fufang tetramethylpyrazine phosphate tablets.

  Journal of chromatographic science 20080101

• In vitro characterization of borneol metabolites by GC-MS upon incubation with rat liver microsomes.

  Journal of chromatographic science 20080101

• The antithrombotic effect of borneol related to its anticoagulant property.

  The American journal of Chinese medicine 20080101

• Spectrophotometric and calorimetric titration studies on molecular recognition of camphor and borneol by nucleobase-modified beta-cyclodextrins.

  The journal of physical chemistry. B 20071025

• Bismuth subgallate/borneol (suile) is superior to bacitracin in the human forearm biopsy model for acute wound healing.

  Advances in skin & wound care 20070901

• The enhancing effect of synthetical borneol on the absorption of tetramethylpyrazine phosphate in mouse.

  International journal of pharmaceutics 20070607

• Monoterpenoid agonists of TRPV3.

  British journal of pharmacology 20070601

• Molecular cytotoxic mechanisms of catecholic polychlorinated biphenyl metabolites in isolated rat hepatocytes.

  Chemico-biological interactions 20070501

• Gas chromatography-mass spectrometry following pressurized hot water extraction and solid-phase microextraction for quantification of eucalyptol, camphor, and borneol in Chrysanthemum flowers.

  Journal of separation science 20070101

• Protective effect of (+/-) isoborneol against 6-OHDA-induced apoptosis in SH-SY5Y cells.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20070101

• [Studies on GC fingerprint of volatile oil of Houttuynia cordata].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20061201

• Chemical composition and antifungal activity of Salvia macrochlamys and Salvia recognita essential oils.

  Journal of agricultural and food chemistry 20060906

• Promoting effect of borneol on the permeability of puerarin eye drops and timolol maleate eye drops through the cornea in vitro.

  Die Pharmazie 20060901

• [Effect of ligustrazine, synthetic borneol on lasting time of ciliary movement].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20060801

• Heme oxygenase induction and biliverdin excretion: implications for the bile fluorescence biomarker.

  Marine environmental research 20060701

• Herbal monoterpene alcohols inhibit propofol metabolism and prolong anesthesia time.

  Life sciences 20060530

• Bile fluorescence, heme oxygenase induction, and increased biliverdin excretion by mixtures of environmental toxicants.

  Aquatic toxicology (Amsterdam, Netherlands) 20060501

• [Effect of absorption enhancers on nasal ginsenoside Rg1 delivery and its nasal ciliotoxicity].

  Yao xue xue bao = Acta pharmaceutica Sinica 20060201

• [Near infrared spectrometry (NIRS) method for the determination of borneol in sustained-release drugs].

  Guang pu xue yu guang pu fen xi = Guang pu 20060101

• [Analysis of volatile constituents from Anemarrhena asphodeloides by GC-MS].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20051101

• Enantiomeric excess determination by fourier transform near-infrared vibrational circular dichroism spectroscopy: simulation of real-time process monitoring.

  Applied spectroscopy 20050901

• Valproic acid glucuronidation is associated with increases in 15-F2t-isoprostane in rats.

  Free radical biology & medicine 20050601

• Conformational rigidification via derivatization facilitates the determination of absolute configuration using chiroptical spectroscopy: a case study of the chiral alcohol endo-borneol.

  The Journal of organic chemistry 20050415

• (+)- And (-)-borneol: efficacious positive modulators of GABA action at human recombinant alpha1beta2gamma2L GABA(A) receptors.

  Biochemical pharmacology 20050401

• Application of quantitative structure-toxicity relationships for acute NSAID cytotoxicity in rat hepatocytes.

  Chemico-biological interactions 20050210

• Determination of enantiomeric excess in samples of chiral molecules using fourier transform vibrational circular dichroism spectroscopy: simulation of real-time reaction monitoring.

  Analytical chemistry 20041201

• [Effect of borneol on the intercellular tight junction and pinocytosis vesicles in vitro blood-brain barrier model].

  Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20040701

• chemical composition, plant genetic differences, antimicrobial and antifungal activity investigation of the essential oil of Rosmarinus officinalis L.

  Journal of agricultural and food chemistry 20040602

• [Synthetical evaluation of promoting effect of some kinds of transdermal enhancers with grey relational cluster method].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20040501

• Glucuronidation of haloperidol by rat liver microsomes: involvement of family 2 UDP-glucuronosyltransferases.

  Life sciences 20040402

• [Measurement of borneol based on near infrared spectroscopy].

  Guang pu xue yu guang pu fen xi = Guang pu 20040201

• Thermodynamics of the molecular and chiral recognition of cycloalkanols and camphor by modified beta-cyclodextrins possessing simple aromatic tethers.

  The Journal of organic chemistry 20040109

• Antioxidant property of volatile oils determined by the ferric reducing ability.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20040101

• Mechanistic studies on the bioactivation of diclofenac: identification of diclofenac-S-acyl-glutathione in vitro in incubations with rat and human hepatocytes.

  Chemical research in toxicology 20031101

• Synergistic effect of bismuth subgallate and borneol, the major components of Sulbogin, on the healing of skin wound.

  Biomaterials 20030801

• Repellent effects of isoborneol on subterranean termites (Isoptera: Rhinotermitidae) in soils of different composition.

  Journal of economic entomology 20030801

• [Studies on the quality standard of xingnao tinctures].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20030801

• High-affinity monoclonal antibodies for detection of the microbial metabolite, 2-methylisoborneol.

  Journal of agricultural and food chemistry 20030618

• UDP-glucuronosyltransferase-dependent bioactivation of clofibric acid to a DNA-damaging intermediate in mouse hepatocytes.

  Chemico-biological interactions 20030506

• Fungicidal property of Curcuma longa L. rhizome-derived curcumin against phytopathogenic fungi in a greenhouse.

  Journal of agricultural and food chemistry 20030312

• Inhibition of acetylcholine-mediated effects by borneol.

  Biochemical pharmacology 20030101

• Antimicrobial and antioxidant activity of the essential oil and methanol extracts of Thymus pectinatus Fisch. et Mey. Var. pectinatus (Lamiaceae).

  Journal of agricultural and food chemistry 20030101

• [Studies on heart-protecting musk pH-dependent gradient-release pellets].

  Yao xue xue bao = Acta pharmaceutica Sinica 20021001

• [Kinetic study on the volatility of menthol and borneol].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20021001

• [Determination of volatile constituents in guanxin suhe wan by gas chromatography-mass spectrometry].

  Se pu = Chinese journal of chromatography 20020701

• Volatile compounds emitted by sclerotia of Sclerotinia minor, Sclerotinia sclerotiorum, and Sclerotium rolfsii.

  Journal of agricultural and food chemistry 20020619

• Composition and antimicrobial activity of the essential oils of Micromeria cristata subsp. phrygia and the enantiomeric distribution of borneol.

  Journal of agricultural and food chemistry 20010901

• Switching of a macromolecular helicity for visual distinction of molecular recognition events.

  Journal of the American Chemical Society 20010822

• Antiviral properties of isoborneol, a potent inhibitor of herpes simplex virus type 1.

  Antiviral research 19990901