465-58-7 | 2-amino-2-methyl-butanoic acid

Packsize	Purity	Availability	Price	Discounted Price
250mg	99%	2 weeks	$55.00	$38.00
1g	99%	2 weeks	$143.00	$100.00
5g	99%	2 weeks	$482.00	$337.00

Description

• Catalog Number: AD29162
• Chemical Name: 2-amino-2-methyl-butanoic acid
• CAS Number: 465-58-7
• Molecular Formula: C5H11NO2
• Molecular Weight: 117.1463
• MDL Number: MFCD00272968
• SMILES: CC(C(=O)O)(CC)N
• NSC Number: 1019

Computed Properties

• Complexity: 103
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 8
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 2
• Undefined Atom Stereocenter Count: 1
• XLogP3: -2.3

Literature

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  Neuroscience 20120628

• R-Isovaline: a subtype-specific agonist at GABA(B)-receptors?

  Neuroscience 20120110

• Photostability of Iiovaline and its precursor 5-Ethyl-5- methylhydantoin exposed to simulated space radiations.

  International journal of molecular sciences 20120101

• Isovaline, a rare amino acid, has anticonvulsant properties in two in vitro hippocampal seizure models by increasing interneuronal activity.

  Epilepsia 20111101

• Distribution and stable isotopic composition of amino acids from fungal peptaibiotics: assessing the potential for meteoritic contamination.

  Astrobiology 20110301

• Configurational assignment of D- and L-isovalines in intact, natural, and synthetic peptides by 2D-NMR spectroscopy.

  Chemistry & biodiversity 20100601

• Analgesic properties of the novel amino acid, isovaline.

  Anesthesia and analgesia 20100401

• (S)-alpha-methyl,alpha-amino acids: a new stereocontrolled synthesis.

  Amino acids 20100301

• Isovaline causes inhibition by increasing potassium conductance in thalamic neurons.

  Neuroscience 20091215

• Aib and iva in the biosphere: neither rare nor necessarily extraterrestrial.

  Chemistry & biodiversity 20090101

• Studies on the selective trifluoroacetolytic scission of native peptaibols and model peptides using HPLC and ESI-CID-MS.

  Chemistry & biodiversity 20081101

• Prebiotic amino acids as asymmetric catalysts.

  Science (New York, N.Y.) 20040220

• A simple and rapid enzymatic assay for the branched-chain alpha-ketoacid dehydrogenase complex using high-performance liquid chromatography.

  Journal of inherited metabolic disease 20040101

• Antibodies directed against L and D isovaline using a chemical derivatizing reagent for the measurement of their enantiomeric ratio in extraterrestrial samples: first step-production and characterization of antibodies.

  Chirality 20020601