4781-83-3 | 2-Iminothiolane HCl

Packsize	Purity	Availability	Price	Discounted Price
100mg	95%	in stock	$32.00	$22.00
250mg	95%	in stock	$40.00	$28.00
500mg	95%	in stock	$80.00	$56.00
1g	95%	in stock	$118.00	$82.00
5g	95%	in stock	$582.00	$407.00
25g	95%	in stock	$2,035.00	$1,424.00

Description

• Catalog Number: AG19839
• Chemical Name: 2-Iminothiolane HCl
• CAS Number: 4781-83-3
• Molecular Formula: C4H8ClNS
• Molecular Weight: 137.631
• MDL Number: MFCD00039013
• SMILES: N=C1CCCS1.Cl
• NSC Number: 340007

Computed Properties

• Complexity: 69.9
• Covalently-Bonded Unit Count: 2
• Heavy Atom Count: 7
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 2

Upstream Synthesis Route

2-Iminothiolane hydrochloride, also known as Traut's reagent, is a versatile compound widely used in chemical synthesis due to its unique properties. This compound is a highly reactive reagent that acts as a sulfhydryl modifier, allowing for the specific derivatization of thiol groups in biomolecules such as proteins and peptides. In chemical synthesis, 2-Iminothiolane hydrochloride is commonly used in the modification of thiol-containing compounds to introduce functional groups or labels for various purposes. One of its key applications is in protein chemistry, where it is used to attach molecules of interest to specific thiol groups on proteins, enabling the study of protein structure, function, and interactions.Furthermore, 2-Iminothiolane hydrochloride is valuable in the creation of thiol-reactive crosslinkers, which are essential for the formation of covalent bonds between biomolecules. This reagent plays a crucial role in the development of conjugates for various biochemical analyses, such as enzyme immunoassays and protein labeling techniques.Overall, the unique reactivity of 2-Iminothiolane hydrochloride makes it an indispensable tool in chemical synthesis, particularly in the modification and functionalization of thiol-containing biomolecules for diverse research and industrial applications.