479-18-5 | Diphylline

Packsize	Purity	Availability	Price	Discounted Price
100mg	98%	in stock	$15.00	$10.00
25g	98%	in stock	$58.00	$41.00
100g	98%	in stock	$105.00	$73.00
500g	98%	in stock	$183.00	$128.00

Description

• Catalog Number: AD24339
• Chemical Name: Diphylline
• CAS Number: 479-18-5
• Molecular Formula: C10H14N4O4
• Molecular Weight: 254.2426
• MDL Number: MFCD00005759
• SMILES: OCC(Cn1cnc2c1c(=O)n(C)c(=O)n2C)O

Computed Properties

• Complexity: 364
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 18
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 3
• Undefined Atom Stereocenter Count: 1
• XLogP3: -1.8

Literature

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  International journal of pharmaceutics 20121015

• Prediction of dissolution time and coating thickness of sustained release formulations using Raman spectroscopy and terahertz pulsed imaging.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20120401

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  Molecular pharmacology 20120301

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  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20120101

• Combination of probenecid-sulphadoxine-pyrimethamine for intermittent preventive treatment in pregnancy.

  Malaria journal 20120101

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  PloS one 20120101

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  International journal of pharmaceutics 20110630

• Validation of Raman spectroscopic procedures in agreement with ICH guideline Q2 with considering the transfer to real time monitoring of an active coating process.

  Journal of pharmaceutical and biomedical analysis 20101201

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

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  FEBS letters 20100219

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• Spectrophotometric and reversed-phase high-performance liquid chromatographic method for the determination of doxophylline in pharmaceutical formulations.

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  BMB reports 20081130

• Hydroxypropyl methylcellulose acetate succinate: potential drug-excipient incompatibility.

  AAPS PharmSciTech 20080901

• Synthesis, pharmacological activity and nitric oxide generation by nitrate derivatives of theophylline.

  The Journal of pharmacy and pharmacology 20080501

• Synthesis and activity against HBV of novel Tetra-seconucleoside analogues of dyphlline having the acyclic chains of ACV and HBG.

  Nucleosides, nucleotides & nucleic acids 20080301

• A comparison of the stability of ertapenem and meropenem in pharmaceutical preparations in solid state.

  Journal of pharmaceutical and biomedical analysis 20080107

• New validated liquid chromatographic and chemometrics-assisted UV spectroscopic methods for the determination of two multicomponent cough mixtures in syrup.

  Journal of AOAC International 20080101

• [Combining LABA and ICS in patients with severe COPD].

  Polskie Archiwum Medycyny Wewnetrznej 20070101

• Extruded and spheronized beads containing Carbopol 974P to deliver nonelectrolytes and salts of weakly basic drugs.

  International journal of pharmaceutics 20060914

• [Clinical observation on shufei granule in improving right ventricular function of patients with chronic pulmonary heart disease].

  Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20060801

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• Rapid determination of acyclovir in plasma and cerebrospinal fluid by micellar electrokinetic chromatography with direct sample injection and its clinical application.

  Electrophoresis 20060201

• HPLC and chemometric assisted spectrophotometric methods for simultaneous determination of diprophylline, phenobarbitone and papaverine hydrochloride.

  Farmaco (Societa chimica italiana : 1989) 20050901

• Optimization and characterization of controlled release multi-particulate beads coated with starch acetate.

  International journal of pharmaceutics 20050427

• Modeling of drug release from partially coated matrices made of a high viscosity HPMC.

  International journal of pharmaceutics 20040519

• Simultaneous determination of theophylline and dyphylline by micellar electrokinetic chromatography and application in drug formulations.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20031005

• Wet granulation fine particle ethylcellulose tablets: effect of production variables and mathematical modeling of drug release.

  AAPS pharmSci 20030601

• Kinetic-spectrophotometric determination of theophylline, dyphylline, and proxyphylline by use of partial least-squares regression.

  Analytical and bioanalytical chemistry 20020901

• Electrophoretic behaviour of pharmacologically active alkylxanthines.

  Journal of chromatography. A 20020315

• Application of micellar electrokinetic chromatography to the quality control of a pharmaceutical preparation containing three bronchodilators.

  Electrophoresis 20020201

• Multi-component kinetic-spectrophotometric analysis. Selection of wavelength and time ranges.

  The Analyst 20010701