4837-90-5 | 4-Methoxyindole

Packsize	Purity	Availability	Price	Discounted Price
1g	≥98%	in stock	$15.00	$10.00
5g	98%	in stock	$20.00	$14.00
10g	98%	in stock	$37.00	$26.00
25g	98%	in stock	$91.00	$64.00

Description

• Catalog Number: AB67839
• Chemical Name: 4-Methoxyindole
• CAS Number: 4837-90-5
• Molecular Formula: C9H9NO
• Molecular Weight: 147.1739
• MDL Number: MFCD00009737
• SMILES: COc1cccc2c1cc[nH]2

Computed Properties

• Complexity: 138
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 1
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 1
• XLogP3: 2.7

Upstream Synthesis Route

4-Methoxy-1H-indole, also known as 4-methoxyindole, is a versatile compound widely utilized in chemical synthesis. As a key building block in organic chemistry, 4-methoxyindole is valued for its ability to participate in various reactions, leading to the synthesis of complex molecules and pharmaceuticals.One of the primary applications of 4-methoxyindole is in the production of indole derivatives, which are crucial in the pharmaceutical industry. By functionalizing the methoxy group, chemists can introduce diverse substituents to the core indole structure, thereby creating novel compounds with potential therapeutic benefits. This compound serves as a valuable precursor for the synthesis of indole-based drugs, such as anti-cancer agents, antimicrobial compounds, and serotonin receptor modulators.Furthermore, 4-methoxyindole can be employed in the preparation of natural product analogs and heterocyclic compounds. Its unique chemical properties make it a valuable starting material for the synthesis of biologically active molecules, agrochemicals, and materials used in diverse fields of research.In summary, 4-methoxy-1H-indole plays a crucial role in chemical synthesis as a key intermediate for the generation of pharmaceuticals, natural product analogs, and other valuable compounds. Its versatility and reactivity make it an indispensable component in organic chemistry research and drug discovery endeavors.

Literature

• Prospective acetylcholinesterase inhibitory activity of indole and its analogs.

  Bioorganic & medicinal chemistry letters 20120415

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101

• Prediction of genotoxicity of chemical compounds by statistical learning methods.

  Chemical research in toxicology 20050601

• HPLC and solubility study of the interaction between pindolol and cyclodextrins.

  Journal of pharmaceutical and biomedical analysis 20050309

• Liquid chromatographic assay for the simultaneous determination of indole-3-carbinol and its acid condensation products in plasma.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030425