486424-20-8 | Azd2858

Packsize	Purity	Availability	Price	Discounted Price
1mg	99%	in stock	$39.00	$28.00
5mg	99%	in stock	$85.00	$60.00
10mg	99%	in stock	$129.00	$90.00
50mg	99%	in stock	$196.00	$137.00
100mg	99%	in stock	$331.00	$232.00
250mg	99%	in stock	$561.00	$393.00

Description

• Catalog Number: AG19700
• Chemical Name: Azd2858
• CAS Number: 486424-20-8
• Molecular Formula: C21H23N7O3S
• Molecular Weight: 453.5174
• MDL Number: MFCD26397072
• SMILES: CN1CCN(CC1)S(=O)(=O)c1ccc(cc1)c1cnc(c(n1)C(=O)Nc1cccnc1)N

Computed Properties

• Complexity: 730
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 32
• Hydrogen Bond Acceptor Count: 9
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 5
• XLogP3: 0.7

Literature

• Discovery of novel potent and highly selective glycogen synthase kinase-3β (GSK3β) inhibitors for Alzheimer's disease: design, synthesis, and characterization of pyrazines.

  Journal of medicinal chemistry 20121108