490-11-9 | Pyridine-3,4-dicarboxylic acid

Packsize	Purity	Availability	Price	Discounted Price
1g	97%	in stock	$16.00	$11.00
25g	97%	in stock	$20.00	$14.00
500g	97%	in stock	$299.00	$209.00

Description

• Catalog Number: AB44336
• Chemical Name: Pyridine-3,4-dicarboxylic acid
• CAS Number: 490-11-9
• Molecular Formula: C7H5NO4
• Molecular Weight: 167.1189
• MDL Number: MFCD00006392
• SMILES: OC(=O)c1cnccc1C(=O)O
• NSC Number: 178

Computed Properties

• Complexity: 204
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 12
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 2
• XLogP3: -0.1

Upstream Synthesis Route

3,4-Pyridinedicarboxylic Acid, also known as isonicotinic acid, plays a crucial role in chemical synthesis as a versatile building block for various compounds. Its unique molecular structure containing a pyridine ring and two carboxylic acid groups makes it a valuable precursor for the synthesis of pharmaceuticals, dyes, and coordination complexes.In organic synthesis, 3,4-pyridinedicarboxylic acid is commonly used as a starting material for the production of pyridine-based drugs such as isoniazid, which is used in the treatment of tuberculosis. It serves as a key intermediate in the synthesis of various heterocyclic compounds with diverse biological activities.Furthermore, in coordination chemistry, the presence of the two carboxylic acid groups in 3,4-pyridinedicarboxylic acid enables it to act as a chelating ligand that can coordinate with metal ions to form stable coordination complexes. These complexes have applications in catalysis, material science, and bioinorganic chemistry.Overall, 3,4-Pyridinedicarboxylic Acid is a versatile compound with wide-ranging applications in chemical synthesis, making it a valuable tool for researchers and chemists working across different fields of study.

Literature

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  Dalton transactions (Cambridge, England : 2003) 20110227

• Synthesis characterization and biological activity study of new schiff and mannich bases and some metal complexes derived from isatin and dithiooxamide.

  Bioinorganic chemistry and applications 20110101

• Poly[(μ(3)-4-carb-oxy-pyridine-3-carboxyl-ato-κN:O:O)(triphenyl-phosphine-κP)silver(I)].

  Acta crystallographica. Section E, Structure reports online 20100901

• Hairpin-shaped tetranuclear palladium(II) complex: synthesis, crystal structure, DNA binding and cytotoxicity activity studies.

  European journal of medicinal chemistry 20100701

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  Journal of medicinal chemistry 20081127

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  Chemistry (Weinheim an der Bergstrasse, Germany) 20070101

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  Dalton transactions (Cambridge, England : 2003) 20050807

• Molecular rectification: application in dye-sensitized solar cells.

  Langmuir : the ACS journal of surfaces and colloids 20050329

• Syntheses, structures, and photoluminescence of a novel class of d10 metal complexes constructed from pyridine-3,4-dicarboxylic acid with different coordination architectures.

  Inorganic chemistry 20040322

• Temperature-controlled hydrothermal synthesis of a 2D ferromagnetic coordination bilayered polymer and a novel 3D network with inorganic Co3(OH)2 ferrimagnetic chains.

  Chemical communications (Cambridge, England) 20040221

• Crystal structures of E. coli nicotinate mononucleotide adenylyltransferase and its complex with deamido-NAD.

  Structure (London, England : 1993) 20020101