491-38-3 | 4H-1-Benzopyran-4-one

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$11.00	$8.00
5g	98%	in stock	$20.00	$14.00
10g	98%	in stock	$29.00	$21.00
25g	98%	in stock	$71.00	$50.00

Description

• Catalog Number: AG19187
• Chemical Name: 4H-1-Benzopyran-4-one
• CAS Number: 491-38-3
• Molecular Formula: C9H6O2
• Molecular Weight: 146.1427
• MDL Number: MFCD00024064
• SMILES: O=c1ccoc2c1cccc2

Computed Properties

• Complexity: 196
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 2
• XLogP3: 1.4

Literature

• Evaluating agarwood products for 2-(2-phenylethyl)chromones using direct analysis in real time time-of-flight mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20121215

• Synthesis and characterization of VO(II), Co(II), Ni(II), Cu(II) and Zn(II) complexes of chromone based azo-linked Schiff base ligand.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20121201

• Chromone containing sulfonamides as potent carbonic anhydrase inhibitors.

  Journal of enzyme inhibition and medicinal chemistry 20121001

• Anti-adipogenic chromone glycosides from Cnidium monnieri fruits in 3T3-L1 cells.

  Bioorganic & medicinal chemistry letters 20121001

• Small molecule activators of proteasome-related HslV peptidase.

  Bioorganic & medicinal chemistry letters 20121001

• 6-Methyl-4-oxo-4H-chromene-3-carbaldehyde.

  Acta crystallographica. Section E, Structure reports online 20121001

• Ethyl (E)-3-(6-methyl-4-oxo-4H-chromen-3-yl)prop-2-enoate.

  Acta crystallographica. Section E, Structure reports online 20121001

• Discovery of MAO-B inhibitors - present status and future directions part I: oxygen heterocycles and analogs.

  Mini reviews in medicinal chemistry 20120901

• Microplate assay for screening the antibacterial activity of Schiff bases derived from substituted benzopyran-4-one.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20120901

• Selected chromone derivatives as inhibitors of monoamine oxidase.

  Bioorganic & medicinal chemistry letters 20120901

• Synthesis and evaluation of substituted chroman-4-one and chromone derivatives as sirtuin 2-selective inhibitors.

  Journal of medicinal chemistry 20120823

• Endo-xylanase GH11 activation by the fungal metabolite eugenitin.

  Biotechnology letters 20120801

• In search for new chemical entities as adenosine receptor ligands: development of agents based on benzo-γ-pyrone skeleton.

  European journal of medicinal chemistry 20120801

• Simple synthesis of carbon-11-labeled chromen-4-one derivatives as new potential PET agents for imaging of DNA-dependent protein kinase (DNA-PK) in cancer.

  Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20120801

• Discovery of novel A3 adenosine receptor ligands based on chromone scaffold.

  Biochemical pharmacology 20120701

• Convenient synthesis of novel geiparvarin analogs with potential anti-cancer activity via click chemistry.

  European journal of medicinal chemistry 20120701

• In vitro antioxidant activity study of novel chromone derivatives.

  Chemical biology & drug design 20120601

• Cyclin-dependent kinase inhibition by flavoalkaloids.

  Mini reviews in medicinal chemistry 20120601

• K2CO3-catalyzed synthesis of chromones and 4-quinolones through the cleavage of aromatic C-O bonds.

  Organic letters 20120601

• Synthesis of the unique angular tricyclic chromone structure proposed for aspergillitine, and its relationship with alkaloid TMC-120B.

  Organic & biomolecular chemistry 20120528

• Conjugate addition of isocyanides to chromone 3-carboxylic acid: an efficient one-pot synthesis of chroman-4-one 2-carboxamides.

  Organic & biomolecular chemistry 20120507

• Development of multiple QSAR models for consensus predictions and unified mechanistic interpretations of the free-radical scavenging activities of chromone derivatives.

  Journal of molecular modeling 20120501

• Identification of novel adenosine A(2A) receptor antagonists by virtual screening.

  Journal of medicinal chemistry 20120308

• Chromone derivatives from Halenia elliptica and their anti-HBV activities.

  Phytochemistry 20120301

• Inhibition of monoamine oxidase by selected C6-substituted chromone derivatives.

  European journal of medicinal chemistry 20120301

• A thiopyranchromenone and other chromone derivatives from an Endolichenic fungus, Preussia africana.

  Journal of natural products 20120224

• New tacrine-4-oxo-4H-chromene hybrids as multifunctional agents for the treatment of Alzheimer's disease, with cholinergic, antioxidant, and β-amyloid-reducing properties.

  Journal of medicinal chemistry 20120209

• Substituted chromones as highly potent nontoxic inhibitors, specific for the breast cancer resistance protein.

  Journal of medicinal chemistry 20120126

• Domino reactions of 2-methyl chromones containing an electron withdrawing group with chromone-fused dienes.

  Organic & biomolecular chemistry 20120121

• 3-Formylchromone interacts with cysteine 38 in p65 protein and with cysteine 179 in IκBα kinase, leading to down-regulation of nuclear factor-κB (NF-κB)-regulated gene products and sensitization of tumor cells.

  The Journal of biological chemistry 20120102

• Synthesis and anti-inflammatory activity of some benzofuran and benzopyran-4-one derivatives.

  Chemical & pharmaceutical bulletin 20120101

• A new chromone from Angelica polymorpha with cytotoxic activity.

  Journal of Asian natural products research 20120101

• Microbial transformations of 7-hydroxyflavanone.

  TheScientificWorldJournal 20120101

• Photoinduced synthesis of new diisochromenochromen-4-ones and their antimicrobial activities.

  TheScientificWorldJournal 20120101

• A novel chromone derivative with anti-inflammatory property via inhibition of ROS-dependent activation of TRAF6-ASK1-p38 pathway.

  PloS one 20120101

• Biotransformation of prim-O-glucosylcimifugin by human intestinal flora and its inhibition on NO production and DPPH free radical.

  Journal of Asian natural products research 20120101

• Chromone and flavonoid alkaloids: occurrence and bioactivity.

  Molecules (Basel, Switzerland) 20111227

• A unified strategy for the asymmetric total syntheses of diversonol and lachnone C.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20111202

• In vitro antimicrobial and antioxidant activities of anthrone and chromone from the latex of Aloe harlana Reynolds.

  Phytotherapy research : PTR 20111201

• 2-(4-Chloro-phen-yl)chromen-4-one.

  Acta crystallographica. Section E, Structure reports online 20111201

• One-pot synthesis of functionalized spirobenzofuranones via MCR involving 3-cyanochromones.

  The Journal of organic chemistry 20111104

• Subchronic toxicity evaluation of aloesin.

  Regulatory toxicology and pharmacology : RTP 20111101

• In vitro and in vivo assessment of the genotoxic activity of aloesin.

  Regulatory toxicology and pharmacology : RTP 20111101

• Synthesis, characterization and biological activity of some new VO(IV), Co(II), Ni(II), Cu(II) and Zn(II) complexes of chromone based NNO Schiff base derived from 2-aminothiazole.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20111101

• [Preparative isolation and purification of five non-volatile compounds from Fructus caryophylli and Flos caryophylli by high-speed counter-current chromatography].

  Se pu = Chinese journal of chromatography 20111101

• Efficient assembly of chromone skeleton from 2,3-allenoic acids and benzynes.

  Organic letters 20111007

• Dietary chromones as antioxidant agents--the structural variable.

  Food & function 20111001

• Identification of benzopyran-4-one derivatives (isoflavones) as positive modulators of GABA(A) receptors.

  ChemMedChem 20110801

• Chromone, a privileged scaffold for the development of monoamine oxidase inhibitors.

  Journal of medicinal chemistry 20110728

• Chromones and coumarins from the dried fructus of Cnidium monnieri.

  Fitoterapia 20110701

• Discovery of new chromone containing sulfonamides as potent inhibitors of bovine cytosolic carbonic anhydrase.

  Bioorganic & medicinal chemistry 20110601

• Natural flavonoids as potential multifunctional agents in prevention of diabetic cataract.

  Interdisciplinary toxicology 20110601

• Mercury ions complexation with a series of heterocyclic derivatives of 3-hydroxychromone: spectral effects and prospects for ultrasensitive Hg2+ probing.

  The journal of physical chemistry. A 20110505

• Synthesis of new chiral heterocyclic Schiff base modulated Cu(II)/Zn(II) complexes: their comparative binding studies with CT-DNA, mononucleotides and cleavage activity.

  Journal of photochemistry and photobiology. B, Biology 20110503

• Highly enantioselective and efficient synthesis of flavanones including pinostrobin through the rhodium-catalyzed asymmetric 1,4-addition.

  Organic letters 20110415

• Transition-metal-free intramolecular Ullmann-type O-arylation: synthesis of chromone derivatives.

  Angewandte Chemie (International ed. in English) 20110411

• Qualitative and quantitative analysis of chemical constituents in traditional Chinese medicinal formula Tong-Xie-Yao-Fang by high-performance liquid chromatography/diode array detection/electrospray ionization tandem mass spectrometry.

  Analytica chimica acta 20110408

• Towards the discovery of a novel class of monoamine oxidase inhibitors: structure-property-activity and docking studies on chromone amides.

  ChemMedChem 20110404

• 7-Fluoro-4-oxochromene-3-carbaldehyde.

  Acta crystallographica. Section E, Structure reports online 20110401

• Cytotoxic metabolites from the soil-derived fungus Exophiala pisciphila.

  Molecules (Basel, Switzerland) 20110330

• Double-tandem [4π+2π]·[2π+2π]·[4π+2π]·[2π+2π] synthetic sequence with photoprotolytic oxametathesis and photoepoxidation in the chromone series.

  The Journal of organic chemistry 20110304

• Three new constituents from the roots of Erythrina variegata and their antibacterial activity against methicillin-resistant Staphylococcus aureus.

  Chemistry & biodiversity 20110301

• New chromone derivative terminalianone from African plant Terminalia brownii Fresen (Combretaceae) in Tanzania.

  Journal of Asian natural products research 20110301

• Tandem reactions leading to bicyclic pyrimidine nucleosides and benzopyran-4-ones.

  The Journal of organic chemistry 20110204

• Chromone-3-carboxylic acid as a potential electron scavenger: a surface-enhanced Raman scattering study.

  Physical chemistry chemical physics : PCCP 20110121

• Chromone 3-phenylcarboxamides as potent and selective MAO-B inhibitors.

  Bioorganic & medicinal chemistry letters 20110115

• What's in a Name? Can Mullein Weed Beat TB Where Modern Drugs Are Failing?

  Evidence-based complementary and alternative medicine : eCAM 20110101

• In vitro study of the PLA2 inhibition and antioxidant activities of Aloe vera leaf skin extracts.

  Lipids in health and disease 20110101

• Zebrafish bioassay-guided natural product discovery: isolation of angiogenesis inhibitors from East African medicinal plants.

  PloS one 20110101

• The effects of topical sodium cromoglicate on itch and flare in human skin induced by intradermal histamine: a randomised double-blind vehicle controlled intra-subject design trial.

  BMC research notes 20110101

• Approaches to neural stem cells and cancer cells based on natural products.

  Chemical & pharmaceutical bulletin 20110101

• Cytotoxicity Effects of Amoora rohituka and chittagonga on Breast and Pancreatic Cancer Cells.

  Evidence-based complementary and alternative medicine : eCAM 20110101

• Variations in Mre11/Rad50/Nbs1 status and DNA damage-induced S-phase arrest in the cell lines of the NCI60 panel.

  BMC cancer 20110101

• Evolutionary Implications and Physicochemical Analyses of Selected Proteins of Type III Polyketide Synthase Family.

  Evolutionary bioinformatics online 20110101

• A new benzofuran glucoside from Ficus tikoua Bur.

  International journal of molecular sciences 20110101

• Structure-based development of small molecule PFKFB3 inhibitors: a framework for potential cancer therapeutic agents targeting the Warburg effect.

  PloS one 20110101

• Protective therapy with novel chromone derivative against Leishmania donovani infection induces Th1 response in vivo.

  Chemotherapy 20110101

• Spectroscopic study of solvent effects on the electronic absorption spectra of flavone and 7-hydroxyflavone in neat and binary solvent mixtures.

  International journal of molecular sciences 20110101

• Structural revision and synthesis of altechromone A.

  Journal of natural products 20101227

• DNA-dependent protein kinase (DNA-PK) inhibitors. Synthesis and biological activity of quinolin-4-one and pyridopyrimidin-4-one surrogates for the chromen-4-one chemotype.

  Journal of medicinal chemistry 20101223

• Characterization of delta-guaiene synthases from cultured cells of Aquilaria, responsible for the formation of the sesquiterpenes in agarwood.

  Plant physiology 20101201

• Electron density studies on hydrogen bonding in two chromone derivatives.

  Acta crystallographica. Section B, Structural science 20101201

• 3-(6-Bromo-4-oxo-4H-chromen-3-yl)-3,4-dihydro-2H-1,2,4-benzothia-diazine-1,1-dione.

  Acta crystallographica. Section E, Structure reports online 20101201

• Effect of different monotherapies on serum nitric oxide and pulmonary functions in children with mild persistent asthma.

  Archives of medical science : AMS 20101201

• Synthesis and evaluation of indole, pyrazole, chromone and pyrimidine based conjugates for tumor growth inhibitory activities--development of highly efficacious cytotoxic agents.

  European journal of medicinal chemistry 20101101

• [Study on volatile components from peel of Aquilaria sinensis and the anti-tumor activity].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20101101

• 3-(6-Fluoro-4-oxo-4H-chromen-3-yl)-3,4-dihydro-2H-1,2,4-benzothia-diazine-1,1-dione.

  Acta crystallographica. Section E, Structure reports online 20101101

• 4-Hy-droxy-3-[(4-hy-droxy-6,7-dimethyl-2-oxo-2H-chromen-3-yl)(4-oxo-4H-chromen-3-yl)meth-yl]-6,7-dimethyl-2H-chromen-2-one.

  Acta crystallographica. Section E, Structure reports online 20101101

• Synthesis of aminoquinazoline derivatives and their antiproliferative activities against melanoma cell line.

  Bioorganic & medicinal chemistry letters 20101001

• New 4H-chromen-4-one and 2H-chromene derivatives as anti-picornavirus capsid-binders.

  Bioorganic & medicinal chemistry 20100901

• Pressurized liquid extraction followed by LC-ESI/MS for analysis of four chromones in Radix Saposhnikoviae.

  Journal of separation science 20100901

• ATM-independent, high-fidelity nonhomologous end joining predominates in human embryonic stem cells.

  Aging 20100901

• A new chromone derivative from Berchemia lineata.

  Yao xue xue bao = Acta pharmaceutica Sinica 20100901

• Design and synthesis of novel hydroxyalkylaminomethylchromones for their IL-5 inhibitory activity.

  Bioorganic & medicinal chemistry 20100701

• Probing the probes: fitness factors for small molecule tools.

  Chemistry & biology 20100625

• (E)-2-styrylchromones as potential anti-norovirus agents.

  Bioorganic & medicinal chemistry 20100615

• Synthesis and evaluation of novel chromone analogs for their inhibitory activity against interleukin-5.

  European journal of medicinal chemistry 20100601

• 2-Ethyl-8-methoxy-methyl-4-oxo-4H-chromen-7-yl (1S,4R)-4,7,7-trimethyl-3-oxo-2-oxabicyclo-[2.2.1]heptane-1-carboxyl-ate.

  Acta crystallographica. Section E, Structure reports online 20100601

• A chromone from Seseli praecox (Apiaceae).

  Natural product communications 20100401

• One-pot synthesis of chromenylfurandicarboxylates and cyclopenta[b]chromenedicarboxylates involving zwitterionic intermediates. A DFT investigation on the regioselectivity of the reaction.

  The Journal of organic chemistry 20100319

• New 2-(2-phenylethyl)chromone derivatives from the seeds of Cucumis melo L var. reticulatus.

  Natural product communications 20100301

• Antibacterial effect of some benzopyrone derivatives.

  European journal of medicinal chemistry 20100101

• Polycyclic polyprenylated acylphloroglucinols and chromone O-glucosides from Hypericum henryi subsp. uraloides.

  Chemistry & biodiversity 20100101

• Structural features and biological properties of ellagitannins in some plant families of the order Myrtales.

  International journal of molecular sciences 20100101

• Forced unbinding of GPR17 ligands from wild type and R255I mutant receptor models through a computational approach.

  BMC structural biology 20100101

• Dynamic dependence on ATR and ATM for double-strand break repair in human embryonic stem cells and neural descendants.

  PloS one 20100101

• [Influence of copper (II) complex on the activity of selected oxidative enzymes].

  Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20100101

• [Influence of chromone compounds on the activity of selected antioxidant enzymes in patients with physical limitations].

  Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20100101

• Biological activities of 2-styrylchromones.

  Mini reviews in medicinal chemistry 20100101

• Anticancer effect and structure-activity analysis of marine products isolated from metabolites of mangrove fungi in the South China Sea.

  Marine drugs 20100101

• Marine drugs from sponge-microbe association--a review.

  Marine drugs 20100101

• Oral and inhaled sodium cromoglicate in the management of systemic mastocytosis: a case report.

  Journal of medical case reports 20100101

• The p110α and p110β isoforms of class I phosphatidylinositol 3-kinase are involved in toll-like receptor 5 signaling in epithelial cells.

  Mediators of inflammation 20100101

• Recent advances in fragment-based QSAR and multi-dimensional QSAR methods.

  International journal of molecular sciences 20100101

• 2-Meth-oxy-3-[(3,4,5-trimethoxy-anilino)methyl-idene]-3,4-dihydro-2H-1-benzopyran-4-one.

  Acta crystallographica. Section E, Structure reports online 20100101

• 5,7-Bis(benz-yloxy)-2-[4-(benz-yloxy)phen-yl]-4H-chromen-4-one.

  Acta crystallographica. Section E, Structure reports online 20100101

• Synthesis and Antibacterial and Antifungal Studies of Novel Nitrogen Containing Heterocycles from 5-Ethylpyridin-2-ethanol.

  Indian journal of pharmaceutical sciences 20100101

• Crystal and molecular structure of lancerodiol-p-hydroxybenzoate.

  Pharmacognosy research 20100101

• Modeling of thermodynamic and physico-chemical properties of coumarins bioactivity against Candida albicans using a Levenberg-Marquardt neural network.

  Advances and applications in bioinformatics and chemistry : AABC 20100101

• Synthesis of 6-aminomethyl derivatives of benzopyran-4-one with dual biological properties: anti-inflammatory-analgesic and antimicrobial.

  European journal of medicinal chemistry 20091201

• 5,7-Dimeth-oxy-2-(4-methoxy-phen-yl)-4H-1-benzopyran-4-one methanol solvate monohydrate.

  Acta crystallographica. Section E, Structure reports online 20091101

• 3,5,7-Trimeth-oxy-2-(4-methoxy-phen-yl)-4H-1-benzopyran-4-one.

  Acta crystallographica. Section E, Structure reports online 20091101

• Modulation of carcinogen metabolizing enzymes by chromanone A; a new chromone derivative from algicolous marine fungus Penicillium sp.

  Environmental toxicology and pharmacology 20091101

• Synthesis and antioxidant properties of new chromone derivatives.

  Bioorganic & medicinal chemistry 20091015

• Total synthesis of euplectin, a natural product with a chromone fused indenone.

  Organic letters 20091001

• Chrotacumines A-D, chromone alkaloids from Dysoxylum acutangulum.

  Journal of natural products 20091001

• Study on the complexation of isoquercitrin with beta-cyclodextrin and its derivatives by spectroscopy.

  Analytica chimica acta 20090914

• Synthesis and antitumor activity of novel dithiocarbamate substituted chromones.

  European journal of medicinal chemistry 20090901

• Energetics of coumarin and chromone.

  The journal of physical chemistry. B 20090813

• Breast cancer resistance protein (BCRP/ABCG2): new inhibitors and QSAR studies by a 3D linear solvation energy approach.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20090812

• N-[2-(6-Methyl-4-oxo-4H-chromen-3-yl)-4-oxothia-zolidin-3-yl]furan-2-carbox-amide N,N-dimethyl-formamide solvate.

  Acta crystallographica. Section E, Structure reports online 20090801

• Flavonoid glucuronides and a chromone from the aquatic macrophyte Stratiotes aloides.

  Journal of natural products 20090522

• Photodimerization of chromone.

  Chemical communications (Cambridge, England) 20090507

• Current mathematical methods used in QSAR/QSPR studies.

  International journal of molecular sciences 20090501

• [Studies on chemical constituents from roots of Angelica polymorpha].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090401

• Photodegradation product of sulcotrione and the physiological response of maize (Zea mays) and white mustard (Sinapis alba).

  Chemosphere 20090301

• First total synthesis of a polyunsaturated chromone metabolite isolated from the brown algae Zonaria tournefortii.

  Organic letters 20090205

• Design and synthesis of 4-aryl-4-oxobutanoic acid amides as calpain inhibitors.

  Bioorganic & medicinal chemistry letters 20090115

• Chromone and chromanone glucosides from Hypericum sikokumontanum and their anti-Helicobacter pylori activities.

  Phytochemistry 20090101

• Synthesis, characterization and DNA-binding properties of the Cu(II) complex with 7-methoxychromone-3-carbaldehyde-benzoylhydrazone.

  Chemical & pharmaceutical bulletin 20090101

• Chromones from the tubers of Eranthis cilicica and their antioxidant activity.

  Phytochemistry 20090101

• Studies on the antimicrobial activity and brine shrimp toxicity of Zeyheria tuberculosa (Vell.) Bur. (Bignoniaceae) extracts and their main constituents.

  Annals of clinical microbiology and antimicrobials 20090101

• Pioglitazone enhances collateral blood flow in ischemic hindlimb of diabetic mice through an Akt-dependent VEGF-mediated mechanism, regardless of PPARgamma stimulation.

  Cardiovascular diabetology 20090101

• Intestinal absorption of aloin, aloe-emodin, and aloesin; A comparative study using two in vitro absorption models.

  Nutrition research and practice 20090101

• InPACdb--Indian plant anticancer compounds database.

  Bioinformation 20090101

• Efficient synthesis of chromone and flavonoid derivatives with diverse heterocyclic units.

  Chemistry, an Asian journal 20081201

• A tropical marine microbial natural products geobibliography as an example of desktop exploration of current research using web visualisation tools.

  Marine drugs 20081201

• pH controlled release of chromone from chromone-Fe3O4 nanoparticles.

  Journal of the American Chemical Society 20081105

• Chemical substructures that enrich for biological activity.

  Bioinformatics (Oxford, England) 20081101

• Tectorigenin monohydrate: an isoflavone from Belamcanda chinensis.

  Acta crystallographica. Section E, Structure reports online 20081101

• QSAR study of p56(lck) protein tyrosine kinase inhibitory activity of flavonoid derivatives using MLR and GA-PLS.

  International journal of molecular sciences 20080901

• Synthesis and biological properties of benzothiazole, benzoxazole, and chromen-4-one analogues of the potent antitumor agent 2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole (PMX 610, NSC 721648).

  Journal of medicinal chemistry 20080828

• 2-(5,7-Dimeth-oxy-4-oxo-4H-chromen-2-yl)phenyl 4-toluene-sulfonate.

  Acta crystallographica. Section E, Structure reports online 20080801

• Relationship between structure and antioxidative properties of some 3-formylchromone derivatives.

  Medicinal chemistry (Shariqah (United Arab Emirates)) 20080701

• 3D-QSAR studies on chromone derivatives as HIV-1 protease inhibitors: application of molecular field analysis.

  Archiv der Pharmazie 20080601

• [Study of the Saposhnikovia divaricata with space mutagenesis by Fourier transform infrared spectroscopy].

  Guang pu xue yu guang pu fen xi = Guang pu 20080601

• Rhodium-catalyzed oxidative coupling between salicylaldehydes and internal alkynes with C-H bond cleavage to produce 2,3-disubstituted chromones.

  Chemistry, an Asian journal 20080505

• Modeling and synthesis of novel tight-binding inhibitors of cytochrome P450 2C9.

  Bioorganic & medicinal chemistry 20080401

• BACE1 (beta-secretase) inhibitory chromone glycosides from Aloe vera and Aloe nobilis.

  Planta medica 20080401

• Indoleamine 2,3-dioxygenase is the anticancer target for a novel series of potent naphthoquinone-based inhibitors.

  Journal of medicinal chemistry 20080327

• 3D-QSAR investigation of synthetic antioxidant chromone derivatives by molecular field analysis.

  International journal of molecular sciences 20080301

• 4'-methoxy-2-styrylchromone a novel microtubule-stabilizing antimitotic agent.

  Biochemical pharmacology 20080215

• Some QSAR studies for a group of sulfonamide Schiff base as carbonic anhydrase CA II inhibitors.

  International journal of molecular sciences 20080201

• Chromone and chromanone derivatives as strand transfer inhibitors of HIV-1 integrase.

  Archives of pharmacal research 20080101

• Influence of phosphorohydrazone derivatives of benzopyrones on polymerization and viscosity of fibrin.

  Acta biochimica Polonica 20080101

• Influence of aromatic and aliphatic moieties on thrombin inhibitors potency.

  The open biochemistry journal 20080101

• Synthesis and Pharmacological Evaluation of (6-Substituted 4-Oxo-4H-chromene-3 yl) methyl N-substituted Aminoacetates.

  Indian journal of pharmaceutical sciences 20080101

• 7-(Hydroxy-meth-yl)-2-(1-hydr-oxy-1-methyl-ethyl)-4-meth-oxy-2,3-dihydro-5H-furo[3,2-g]chromen-5-one methanol hemisolvate.

  Acta crystallographica. Section E, Structure reports online 20080101

• Effect of beta-cyclodextrin nanocavity confinement on the photophysics of robinetin.

  Journal of photochemistry and photobiology. B, Biology 20071214

• Spectra and DNA-binding affinities of Copper(II), Nickel(II) complexes with a novel glycine Schiff base derived from chromone.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20071101

• Synthesis and biological evaluation of the mitochondrial complex 1 inhibitor 2-[4-(4-fluorobutyl)benzylsulfanyl]-3-methylchromene-4-one as a potential cardiac positron emission tomography tracer.

  Journal of medicinal chemistry 20070906

• (1)H and (13)C NMR signal assignments of paecilin A and B, two new chromone derivatives from mangrove endophytic fungus Paecilomyces sp. (tree 1-7).

  Magnetic resonance in chemistry : MRC 20070901

• Design, syntheses, and antitumor activity of novel chromone and aurone derivatives.

  Bioorganic & medicinal chemistry 20070801

• Structure of the cytochrome b6f complex: quinone analogue inhibitors as ligands of heme cn.

  Journal of molecular biology 20070629

• Nodulisporol and Nodulisporone, novel specific inhibitors of human DNA polymerase lambda from a fungus, Nodulisporium sp.

  Bioorganic & medicinal chemistry 20070501

• A comparison of stigmatellin conformations, free and bound to the photosynthetic reaction center and the cytochrome bc1 complex.

  Journal of molecular biology 20070420

• Acridone derivatives: design, synthesis, and inhibition of breast cancer resistance protein ABCG2.

  Bioorganic & medicinal chemistry 20070415

• A chromone analog inhibits TNF-alpha induced expression of cell adhesion molecules on human endothelial cells via blocking NF-kappaB activation.

  Bioorganic & medicinal chemistry 20070415

• Synthesis and insecticidal activity of chromanone and chromone analogues of diacylhydrazines.

  Bioorganic & medicinal chemistry 20070301

• Fingerprint analysis of the fruits of Cnidium monnieri extract by high-performance liquid chromatography-diode array detection-electrospray ionization tandem mass spectrometry.

  Journal of pharmaceutical and biomedical analysis 20070219

• The responses of HT22 cells to the blockade of mitochondrial complexes and potential protective effect of selenium supplementation.

  International journal of biological sciences 20070101

• Anti-cancer and immunostimulatory activity of chromones and other constituents from Cassia petersiana.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20070101

• Biological activity of 3-formylchromones and related compounds.

  In vivo (Athens, Greece) 20070101

• Synthesis, spectroscopy and alkylating properties of Pd(II) complexes of phosphorohydrazones of coumarin and chromone with potential antibacterial activity.

  Acta poloniae pharmaceutica 20070101

• Dietary flavonoids attenuate tumor necrosis factor alpha-induced adhesion molecule expression in human aortic endothelial cells. Structure-function relationships and activity after first pass metabolism.

  The Journal of biological chemistry 20061201

• In vivo antitumor, in vitro antibacterial activity and alkylating properties of phosphorohydrazine derivatives of coumarin and chromone.

  European journal of medicinal chemistry 20061101

• Synthesis of 2,3,6,8-tetrasubstituted chromone scaffolds.

  The Journal of organic chemistry 20060901

• Synthesis, molecular characterization, and biological activity of novel synthetic derivatives of chromen-4-one in human cancer cells.

  Journal of medicinal chemistry 20060629

• Chromone derivatives from the filamentous fungus Lachnum sp. BCC 2424.

  Journal of natural products 20060601

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• Phototransformation of the herbicide sulcotrione on maize cuticular wax.

  Environmental science & technology 20060501

• [The synthesis of arginine derivatives of chromone and azauracil].

  Bioorganicheskaia khimiia 20060101

• A new chromone from Cassia nodosa.

  Journal of Asian natural products research 20060101

• Structure-Activity Relationships of Synthetic Coumarins as HIV-1 Inhibitors.

  Bioinorganic chemistry and applications 20060101

• Discovery of potent chromen-4-one inhibitors of the DNA-dependent protein kinase (DNA-PK) using a small-molecule library approach.

  Journal of medicinal chemistry 20051201

• Sesquiterpene chromones from Ferula fukanensis and their nitric oxide production inhibitory effects.

  Journal of natural products 20051201

• Synthesis and in vivo analgesic and anti-inflammatory activity of some bi heterocyclic coumarin derivatives.

  European journal of medicinal chemistry 20050901

• Inhibition of epidermal growth factor-induced cell transformation by tannins.

  Phytochemistry 20050901

• Reactions of 3-formylchromone with active methylene and methyl compounds and some subsequent reactions of the resulting condensation products.

  Molecules (Basel, Switzerland) 20050831

• Time dependent density functional theory study of electronic absorption properties of lead(II) complexes with a series of hydroxyflavones.

  The journal of physical chemistry. A 20050804

• Rotenoids and isoflavones from Sarcolobus globosus.

  Planta medica 20050801

• Carbonic anhydrase inhibitors. Inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, IX, and XII with Schiff's bases incorporating chromone and aromatic sulfonamide moieties, and their zinc complexes.

  Bioorganic & medicinal chemistry letters 20050615

• Synthesis and biological evaluation of chromone carboxamides as calpain inhibitors.

  Bioorganic & medicinal chemistry letters 20050602

• Chemical constituents from Cimicifuga foetida.

  Journal of Asian natural products research 20050401

• Donor-substituted phenyl-pi-chromones: electrochemiluminescence and intriguing electronic properties.

  Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20050401

• (2Z)-3-(5-Hydroxy-4-oxo-4H-chromen-3-yl)acrylonitrile.

  Acta crystallographica. Section C, Crystal structure communications 20050401

• [Treatment of allergic rhinitis: update 2005].

  MMW Fortschritte der Medizin 20050310

• Synthesis and hybridization properties of the conjugates of oligonucleotides and stabilization agents. Part 3.

  Bioorganic & medicinal chemistry 20050301

• Mechanism of action and resistant profile of anti-HIV-1 coumarin derivatives.

  Virology 20050220

• A new chromone from Ficus lyrata.

  Journal of Asian natural products research 20050201

• Selective benzopyranone and pyrimido[2,1-a]isoquinolin-4-one inhibitors of DNA-dependent protein kinase: synthesis, structure-activity studies, and radiosensitization of a human tumor cell line in vitro.

  Journal of medicinal chemistry 20050127

• [Preparative isolation and purification of cinnamoyl-C-glycoside chromone from aloe vera by high-speed countercurrent chromatography].

  Se pu = Chinese journal of chromatography 20050101

• The antioxidative effect of icariin in human erythrocytes against free-radical-induced haemolysis.

  The Journal of pharmacy and pharmacology 20041201

• Molecular control of a bimodal distribution of quinone-analogue inhibitor binding sites in the cytochrome b(6)f complex.

  Journal of molecular biology 20041119

• Phosphorohydrazines of 4-oxo-4H-1-benzopyran and 1-benzopyran-2,4-dione exhibit antitumor activity against L1210 leukemia.

  Die Pharmazie 20040901

• Anti-AIDS agents. 60. Substituted 3'R,4'R-di-O-(-)-camphanoyl-2',2'-dimethyldihydropyrano[2,3-f]chromone (DCP) analogues as potent anti-HIV agents.

  Journal of medicinal chemistry 20040729

• Conformational analysis of the biflavanoid GB2 and a polyhydroxylated flavanone-chromone of Cratoxylum neriifolium.

  Planta medica 20040701

• Aryl hydrocarbon receptor activation of an antitumor aminoflavone: basis of selective toxicity for MCF-7 breast tumor cells.

  Molecular cancer therapeutics 20040601

• New metabolic pathways for flavanones catalyzed by rat liver microsomes.

  Drug metabolism and disposition: the biological fate of chemicals 20040401

• Diterpene derivative and chromone from Hypericum perforatum.

  Natural product research 20040201

• The design and synthesis of novel inhibitors of NADH:ubiquinone oxidoreductase.

  Bioorganic & medicinal chemistry letters 20040119

• Synthesis and pharmaceutical activity of new series of chromonyl derivatives.

  Bollettino chimico farmaceutico 20040101

• Chromone studies. Part 13. Synthesis and electron-impact mass spectrometric studies of 5-hydroxy-2-isopropyl-7-methoxychromone, a constituent of the medicinal plant Baeckea frutescens, and side-chain analogues.

  Journal of natural products 20030801

• Synthesis and evaluation of antirhinovirus activity of 3-hydroxy and 3-methoxy 2-styrylchromones.

  Antiviral chemistry & chemotherapy 20030701

• Four new 2-(2-phenylethyl)chromone derivatives from withered wood of Aquilaria sinensis.

  Chemical & pharmaceutical bulletin 20030501

• Acaricidal activity of tonka bean extracts. Synthesis and structure-activity relationships of bioactive derivatives.

  Journal of natural products 20030501

• Structural requirement of isoflavonones for the inhibitory activity of interleukin-5.

  European journal of medicinal chemistry 20030501

• Perturbation of planarity as the possible mechanism of solvent-dependent variations of fluorescence quantum yield in 2-aryl-3-hydroxychromones.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20030301

• Highly regioselective Friedländer annulations with unmodified ketones employing novel amine catalysts: syntheses of 2-substituted quinolines, 1,8-naphthyridines, and related heterocycles.

  The Journal of organic chemistry 20030124

• Insect antifeedant activity of flavones and chromones against Spodoptera litura.

  Journal of agricultural and food chemistry 20030115

• Coumarin, chromone, and 4(3H)-pyrimidinone novel bicyclic and tricyclic derivatives as antiplatelet agents: synthesis, biological evaluation, and comparative molecular field analysis.

  Bioorganic & medicinal chemistry 20030102

• Novel chromone derivatives from the fungus Aspergillus versicolor isolated from the marine sponge Xestospongia exigua.

  Journal of natural products 20030101

• Naphthoquinone derivatives and lignans from the Paraguayan crude drug 'tayï pytá' (Tabebuia heptaphylla, Bignoniaceae).

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20030101

• Antifungal methylphenone derivatives and 5-methylcoumarins from Mutisia friesiana.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20030101

• Chemical constituents of Stellera chamaejasme L.

  Journal of Asian natural products research 20021201

• Chromone and phenanthrene alkaloids from Dennettia tripetala.

  Chemical & pharmaceutical bulletin 20021201

• The isolation of two new chromone derivatives from the New Zealand fungus Tolypocladium extinguens.

  Journal of natural products 20021101

• Central nervous system activity of Leucas inflata Benth. in mice.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20020901

• Radioprotective effects of 2-imino-3-[(chromone-2-yl)carbonyl] thiazolidines against gamma-irradiation in mice.

  Journal of radiation research 20020901

• Chromatography of the chromone and flavonoid alkaloids.

  Journal of chromatography. A 20020816

• Binding of 1-benzopyran-4-one derivatives to aldose reductase: a free energy perturbation study.

  Bioorganic & medicinal chemistry 20020501

• Two benzophenone O-arabinosides and a chromone from Hypericum annulatum.

  Phytochemistry 20020401

• Mushroom tyrosinase inhibition activity of some chromones.

  Chemical & pharmaceutical bulletin 20020301

• Six new 2-(2-phenylethyl)chromones from Agarwood.

  Chemical & pharmaceutical bulletin 20020301

• Synthesis, antimicrobial, and alkylating properties of 3-phosphonic derivatives of chromone.

  Archiv der Pharmazie 20011201

• Electrolytic partial fluorination of organic compounds. 55. Highly regio- and stereoselective anodic monofluorination of 2,3-dihydrochroman-4-one and chromone derivatives.

  The Journal of organic chemistry 20011116

• Studies on constituents from Chamaecyparis pisifera and antibacterial activity of diterpenes.

  Chemical & pharmaceutical bulletin 20011101

• Advances in cancer therapy with plant based natural products.

  Current medicinal chemistry 20011001

• S17834, a new inhibitor of cell adhesion and atherosclerosis that targets nadph oxidase.

  Arteriosclerosis, thrombosis, and vascular biology 20011001

• Coumarins derivatives as dual inhibitors of acetylcholinesterase and monoamine oxidase.

  Journal of medicinal chemistry 20010913

• [Color reactions for identification of sodium cromoglycate].

  Die Pharmazie 20010501

• [Therapy of allergic rhinitis].

  Therapeutische Umschau. Revue therapeutique 20010501

• A new class of nonsteroidal aromatase inhibitors: design and synthesis of chromone and xanthone derivatives and inhibition of the P450 enzymes aromatase and 17 alpha-hydroxylase/C17,20-lyase.

  Journal of medicinal chemistry 20010301

• Synthesis and biological evaluation of some novel 4H-benzopyran-4-one derivatives as nonsteroidal antiestrogens.

  European journal of medicinal chemistry 20010301

• [Studies on quality specification standards for Saposhnicovia divaricata (Turcz.) Schischk].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20010301

• Coumarin and chromen-4-one analogues as tautomerase inhibitors of macrophage migration inhibitory factor: discovery and X-ray crystallography.

  Journal of medicinal chemistry 20010215

• Inhibition of neutrophil O(2)(-) production by unsymmetrical methylene derivatives of benzopyrans: their use as potential antiinflammatory agents.

  European journal of medicinal chemistry 20010101