-
Nornicotine and Nicotine Induced Neovascularization via Increased VEGF/PEDF Ratio.
Ophthalmic research 20150101
-
Nornicotine application on cockroach dorsal unpaired median neurons induces two distinct ionic currents: implications of different nicotinic acetylcholine receptors.
Neuroscience letters 20120614
-
Determination of nicotine exposure in dogs subjected to passive smoking using methanol extraction of hair followed by hydrophilic interaction chromatography in combination with Fourier transform mass spectrometry.
Talanta 20120115
-
Nicotine modulates alcohol-seeking and relapse by alcohol-preferring (P) rats in a time-dependent manner.
Alcoholism, clinical and experimental research 20120101
-
An interspecific Nicotiana hybrid as a useful and cost-effective platform for production of animal vaccines.
PloS one 20120101
-
A one-year monitoring of nicotine use in sport: frontier between potential performance enhancement and addiction issues.
Forensic science international 20111210
-
Chronic stress and Alzheimer's disease-like pathogenesis in a rat model: prevention by nicotine.
Current neuropharmacology 20111201
-
Emerging Pharmacological Properties of Cholinergic Synaptic Transmission: Comparison between Mammalian and Insect Synaptic and Extrasynaptic Nicotinic Receptors.
Current neuropharmacology 20111201
-
Protonating and determining myosmine intactly by association with citrate anion.
The Analyst 20111121
-
Simultaneous quantification of nicotine and metabolites in rat brain by liquid chromatography-tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111115
-
Thirdhand tobacco smoke: emerging evidence and arguments for a multidisciplinary research agenda.
Environmental health perspectives 20110901
-
Validation of a liquid chromatography-tandem mass spectrometry method for the detection of nicotine biomarkers in hair and an evaluation of wash procedures for removal of environmental nicotine.
Journal of analytical toxicology 20110701
-
Nicotine exposure and metabolizer phenotypes from analysis of urinary nicotine and its 15 metabolites by LC-MS.
Bioanalysis 20110401
-
Nicotine and metabolites in paired umbilical cord tissue and meconium specimens.
Therapeutic drug monitoring 20110201
-
In silico theoretical molecular modeling for Alzheimer's disease: the nicotine-curcumin paradigm in neuroprotection and neurotherapy.
International journal of molecular sciences 20110101
-
Mutation scanning of peach floral genes.
BMC plant biology 20110101
-
Targeting nicotine addiction: the possibility of a therapeutic vaccine.
Drug design, development and therapy 20110101
-
Lethal impacts of cigarette smoke in cultured tobacco cells.
Tobacco induced diseases 20110101
-
Molecular dynamics analysis reveals structural insights into mechanism of nicotine N-demethylation catalyzed by tobacco cytochrome P450 mono-oxygenase.
PloS one 20110101
-
Transcriptome analysis of Bupleurum chinense focusing on genes involved in the biosynthesis of saikosaponins.
BMC genomics 20110101
-
Three nicotine demethylase genes mediate nornicotine biosynthesis in Nicotiana tabacum L.: functional characterization of the CYP82E10 gene.
Phytochemistry 20101201
-
Clustered transcription factor genes regulate nicotine biosynthesis in tobacco.
The Plant cell 20101001
-
A novel pathway for nicotine degradation by Aspergillus oryzae 112822 isolated from tobacco leaves.
Research in microbiology 20100901
-
Identification and quantification of nicotine biomarkers in human oral fluid from individuals receiving low-dose transdermal nicotine: a preliminary study.
Journal of analytical toxicology 20100901
-
Natural toxins for use in pest management.
Toxins 20100801
-
Fundamental reaction pathways for cytochrome P450-catalyzed 5'-hydroxylation and N-demethylation of nicotine.
The journal of physical chemistry. B 20100715
-
Extinction with varenicline and nornicotine, but not ABT-418, weakens conditioned responding evoked by the interoceptive stimulus effects of nicotine.
Neuropharmacology 20100601
-
The pyrolysis of (-)-(S)-nicotine: racemization and decomposition.
Chirality 20100505
-
A novel validated procedure for the determination of nicotine, eight nicotine metabolites and two minor tobacco alkaloids in human plasma or urine by solid-phase extraction coupled with liquid chromatography-electrospray ionization-tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100315
-
The analgesic and toxic effects of nornicotine enantiomers alone and in interaction with morphine in rodent models of acute and persistent pain.
Pharmacology, biochemistry, and behavior 20100101
-
Quantitation of nicotine, its metabolites, and other related alkaloids in urine, serum, and plasma using LC-MS-MS.
Methods in molecular biology (Clifton, N.J.) 20100101
-
The pituri story: a review of the historical literature surrounding traditional Australian Aboriginal use of nicotine in Central Australia.
Journal of ethnobiology and ethnomedicine 20100101
-
Biochemistry and occurrence of o-demethylation in plant metabolism.
Frontiers in physiology 20100101
-
The addition of five minor tobacco alkaloids increases nicotine-induced hyperactivity, sensitization and intravenous self-administration in rats.
The international journal of neuropsychopharmacology 20091101
-
Validation of a GC-FID method for rapid quantification of nicotine in fermented extracts prepared from Nicotiana tabacum fresh leaves and studies of nicotine metabolites.
Journal of pharmaceutical and biomedical analysis 20090712
-
Drugs of abuse that mediate advanced glycation end product formation: a chemical link to disease pathology.
Accounts of chemical research 20090519
-
The A622 gene in Nicotiana glauca (tree tobacco): evidence for a functional role in pyridine alkaloid synthesis.
Plant molecular biology 20090201
-
Smoking and Parkinson's disease: does nicotine affect alpha-synuclein fibrillation?
Biochimica et biophysica acta 20090201
-
Determination of nicotine, cotinine, and related alkaloids in human urine and saliva by automated in-tube solid-phase microextraction coupled with liquid chromatography-mass spectrometry.
Journal of pharmaceutical and biomedical analysis 20090115
-
Enantioseparation of nicotine alkaloids in cigarettes by CE using sulfated beta-CD as a chiral selector and a capillary coated with amino groups.
Electrophoresis 20090101
-
Nicotine content and delivery across tobacco products.
Handbook of experimental pharmacology 20090101
-
[Development of analytical method for determination nicotine metabolites in urine].
Przeglad lekarski 20090101
-
Meconium nicotine and metabolites by liquid chromatography-tandem mass spectrometry: differentiation of passive and nonexposure and correlation with neonatal outcome measures.
Clinical chemistry 20081201
-
Why does anatabine, but not nicotine, accumulate in jasmonate-elicited cultured tobacco BY-2 cells?
Plant & cell physiology 20080801
-
Nicotine metabolism in pregnant and nonpregnant rabbits.
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20080801
-
RNA interference (RNAi)-induced suppression of nicotine demethylase activity reduces levels of a key carcinogen in cured tobacco leaves.
Plant biotechnology journal 20080501
-
[Rapid determination of alkaloids in tobacco using gas chromatography-mass spectrometry with full scan-selected ion monitoring mode].
Se pu = Chinese journal of chromatography 20080501
-
Enantiomeric analysis of anatabine, nornicotine and anabasine in commercial tobacco by multi-dimensional gas chromatography and mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080401
-
CYP82E4-mediated nicotine to nornicotine conversion in tobacco is regulated by a senescence-specific signaling pathway.
Plant molecular biology 20080301
-
Quantification of nicotine, cotinine, trans-3'-hydroxycotinine, nornicotine and norcotinine in human meconium by liquid chromatography/tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080215
-
Separation and measurement of plant alkaloid enantiomers by RP-HPLC analysis of their Fmoc-Alanine analogs.
Phytochemical analysis : PCA 20080101
-
Nornicotine-organocatalyzed aqueous reduction of alpha,beta-unsaturated aldehydes.
Chemical communications (Cambridge, England) 20071214
-
Isolation and characterization of the cytochrome P450 gene CYP82E5v2 that mediates nicotine to nornicotine conversion in the green leaves of tobacco.
Plant & cell physiology 20071101
-
Domestication of plants in the Americas: insights from Mendelian and molecular genetics.
Annals of botany 20071001
-
Analyses of tobacco alkaloids by cation-selective exhaustive injection sweeping microemulsion electrokinetic chromatography.
Journal of chromatography. A 20070914
-
Endogenous formation of N'-nitrosonornicotine in F344 rats in the presence of some antioxidants and grape seed extract.
Journal of agricultural and food chemistry 20070822
-
Effects of tobacco and cigarette smoke extracts on serotonergic raphe neurons in the rat.
Neuroreport 20070611
-
The pharmacological activity of nicotine and nornicotine on nAChRs subtypes: relevance to nicotine dependence and drug discovery.
Journal of neurochemistry 20070401
-
Expression of the receptor of advanced glycation end products in the gingival tissue of smokers with generalized periodontal disease and after nornicotine induction in primary gingival epithelial cells.
Journal of periodontology 20070401
-
Nornicotine inhibition of dopamine transporter function in striatum via nicotinic receptor activation.
Synapse (New York, N.Y.) 20070301
-
Effects of nornicotine enantiomers on intravenous S(-)-nicotine self-administration and cardiovascular function in rats.
Psychopharmacology 20070201
-
Functional analysis of nicotine demethylase genes reveals insights into the evolution of modern tobacco.
The Journal of biological chemistry 20070105
-
Characterisation of nicotine and related compounds using electrospray ionisation with ion trap mass spectrometry and with quadrupole time-of-flight mass spectrometry and their detection by liquid chromatography/electrospray ionisation mass spectrometry.
Rapid communications in mass spectrometry : RCM 20070101
-
Inactivation of the cytochrome P450 gene CYP82E2 by degenerative mutations was a key event in the evolution of the alkaloid profile of modern tobacco.
The New phytologist 20070101
-
Genetic engineering of Nicotiana tabacum for reduced nornicotine content.
Journal of agricultural and food chemistry 20061129
-
Synthesis and pharmacological characterization of nicotinic acetylcholine receptor properties of (+)- and (-)-pyrido-[3,4-b]homotropanes.
Journal of medicinal chemistry 20060601
-
Re: Receptor for advanced glycation end product (RAGE) upregulation in human gingival fibroblasts incubated with nornicotine. Katz J, Caudle RM, Bhattacharyya I, Stewart CM, Cohen DM (2005;76:1171-1174).
Journal of periodontology 20060201
-
CYP2A6 AND CYP2B6 are involved in nornicotine formation from nicotine in humans: interindividual differences in these contributions.
Drug metabolism and disposition: the biological fate of chemicals 20051201
-
Nicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-butanone metabolism by cytochrome P450 2B6.
Drug metabolism and disposition: the biological fate of chemicals 20051201
-
Acute and subacute effects of tobacco alkaloids, tobacco-specific nitrosamines and phenethyl isothiocyanate on N'-nitrosonornicotine metabolism in rats.
Toxicology 20051115
-
Nicotine demethylation in Nicotiana cell suspension cultures: N'-formylnornicotine is not involved.
Phytochemistry 20051001
-
A general procedure for the enantioselective synthesis of the minor tobacco alkaloids nornicotine, anabasine, and anatabine.
The AAPS journal 20050901
-
Nicotine 5'-oxidation and methyl oxidation by P450 2A enzymes.
Drug metabolism and disposition: the biological fate of chemicals 20050801
-
Receptor for advanced glycation end product (RAGE) upregulation in human gingival fibroblasts incubated with nornicotine.
Journal of periodontology 20050701
-
Hammett correlation of nornicotine analogues in the aqueous aldol reaction: implications for green organocatalysis.
The Journal of organic chemistry 20050429
-
Iminium metabolite mechanism for nicotine toxicity and addiction: Oxidative stress and electron transfer.
Medical hypotheses 20050101
-
Determination of the natural abundance delta15N of nicotine and related alkaloids by gas chromatography/isotope ratio mass spectrometry.
Rapid communications in mass spectrometry : RCM 20050101
-
Electronic properties of amino acid side chains: quantum mechanics calculation of substituent effects.
BMC chemical biology 20050101
-
Simultaneous and sensitive measurement of anabasine, nicotine, and nicotine metabolites in human urine by liquid chromatography-tandem mass spectrometry.
Clinical chemistry 20041201
-
Nornicotine aqueous aldol reactions: synthetic and theoretical investigations into the origins of catalysis.
The Journal of organic chemistry 20041001
-
Two-site binding of beta-cyclodextrin to the Alzheimer Abeta(1-40) peptide measured with combined PFG-NMR diffusion and induced chemical shifts.
Biochemistry 20040525
-
In vitro microsomal [correction of mircosomal] metabolism of N-benzyl and N-benzoylnornicotine derivates by rat.
European journal of drug metabolism and pharmacokinetics 20040101
-
Stimulation of nicotine demethylation by NaHCO(3) treatment using greenhouse-grown burley tobacco.
Journal of agricultural and food chemistry 20031217
-
Genotoxic effects of myosmine in human lymphocytes and upper aerodigestive tract epithelial cells.
Toxicology 20031105
-
Fast analysis of nicotine related alkaloids in tobacco and cigarette smoke by megabore capillary gas chromatography.
Journal of chromatography. A 20031031
-
The nicotinic pharmacophore: thermodynamics of the hydrogen-bonding complexation of nicotine, nornicotine, and models.
The Journal of organic chemistry 20031017
-
Dopaminergic and cholinergic involvement in the discriminative stimulus effects of nicotine and cocaine in rats.
Psychopharmacology 20030601
-
N,N-disubstituted piperazines: synthesis and affinities at alpha4beta2(*) and alpha7(*) neuronal nicotinic acetylcholine receptors.
Bioorganic & medicinal chemistry letters 20030106
-
Long-lasting occupancy of central nicotinic acetylcholine receptors after smoking: a PET study in monkeys.
Journal of neurochemistry 20030101
-
Locomotor stimulant effects of nornicotine: role of dopamine.
Pharmacology, biochemistry, and behavior 20021201
-
Anabasine and anatabine as biomarkers for tobacco use during nicotine replacement therapy.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20021201
-
Determination of nicotine and other minor alkaloids in international cigarettes by solid-phase microextraction and gas chromatography/mass spectrometry.
Analytical chemistry 20021001
-
Site of protonation of nicotine and nornicotine in the gas phase: pyridine or pyrrolidine nitrogen?
Journal of the American Chemical Society 20020904
-
Simultaneous analysis of nicotine, nicotine metabolites, and tobacco alkaloids in serum or urine by tandem mass spectrometry, with clinically relevant metabolic profiles.
Clinical chemistry 20020901
-
Aqueous aldol catalysis by a nicotine metabolite.
Journal of the American Chemical Society 20020403
-
Evidence for the involvement of tetrahydrofolate in the demethylation of nicotine by Nicotiana plumbaginifolia cell-suspension cultures.
Planta 20020401
-
Determination of tobacco alkaloids by gas chromatography with nitrogen-phosphorus detection.
Analytical and bioanalytical chemistry 20020401
-
Contributory role for nornicotine in nicotine neuropharmacology: nornicotine-evoked [3H]dopamine overflow from rat nucleus accumbens slices.
Biochemical pharmacology 20011215
-
Nornicotine, a nicotine metabolite and tobacco alkaloid: desensitization of nicotinic receptor-stimulated dopamine release from rat striatum.
European journal of pharmacology 20010928
-
A new and direct synthesis of 2-substituted pyrrolidines.
The Journal of organic chemistry 20010907
-
The effect of tobacco smoke, nicotine, and cotinine on the mutagenicity of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL).
Mutation research 20010725
-
High-performance liquid chromatographic determination of pyridostigmine bromide, nicotine, and their metabolites in rat plasma and urine.
Journal of chromatographic science 20010701
-
Quantification of nicotine, chlorpyrifos and their metabolites in rat plasma and urine using high-performance liquid chromatography.
Journal of chromatography. B, Biomedical sciences and applications 20010615
-
Determination of tobacco alkaloids in single plant cells by capillary electrophoresis.
Journal of chromatography. A 20010511
-
Neuronal nicotinic acetylcholine receptor binding affinities of boron-containing nicotine analogues.
Bioorganic & medicinal chemistry letters 20010507
-
In vitro effects of nicotine on mitochondrial respiration and superoxide anion generation.
Brain research 20010504
-
Accumulation of nicotine and its metabolites in rat brain after intermittent or continuous peripheral administration of [2'-(14)C]nicotine.
Drug metabolism and disposition: the biological fate of chemicals 20010501
-
Comparison of methods for extraction of tobacco alkaloids.
Journal of AOAC International 20010101
-
Enhancement of haloperidol-induced catalepsy by nicotine: an investigation of possible mechanisms.
Canadian journal of physiology and pharmacology 20001101