4961-41-5 | Tetraethylenepentamine pentahydrochloride

Packsize	Purity	Availability	Price	Discounted Price
5g	94%	in stock	$67.00	$47.00
25g	94%	in stock	$278.00	$195.00

Description

• Catalog Number: AB79522
• Chemical Name: Tetraethylenepentamine pentahydrochloride
• CAS Number: 4961-41-5
• Molecular Formula: C8H28Cl5N5
• Molecular Weight: 371.6064
• MDL Number: MFCD00083503
• SMILES: NCCNCCNCCNCCN.Cl.Cl.Cl.Cl.Cl

Computed Properties

• Complexity: 78.6
• Covalently-Bonded Unit Count: 6
• Heavy Atom Count: 18
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 10
• Rotatable Bond Count: 10

Literature

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  Experimental biology and medicine (Maywood, N.J.) 20151101

• Susceptibility of PTEN-positive metastatic tumors to small interfering RNA targeting the mammalian target of rapamycin.

  Nanomedicine : nanotechnology, biology, and medicine 20150101

• Advanced cancer therapy by integrative antitumor actions via systemic administration of miR-499.

  Journal of controlled release : official journal of the Controlled Release Society 20140510

• Polyaspartamide derivative nanoparticles with tunable surface charge achieve highly efficient cellular uptake and low cytotoxicity.

  Langmuir : the ACS journal of surfaces and colloids 20120807

• Copper is required for cobalt-induced transcriptional activity of hypoxia-inducible factor-1.

  The Journal of pharmacology and experimental therapeutics 20120801

• Spectroscopic investigation into oxidative degradation of silica-supported amine sorbents for CO(2) capture.

  ChemSusChem 20120801

• RGD-based active targeting of novel polycation liposomes bearing siRNA for cancer treatment.

  Journal of controlled release : official journal of the Controlled Release Society 20120610

• Potential biosorbent based on sugarcane bagasse modified with tetraethylenepentamine for removal of eosin Y.

  International journal of biological macromolecules 20120401

• Amino-functionalized nano-size composite materials for dispersive solid-phase extraction of phosphate in water samples.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20120101

• Chemical modification of chitosan by tetraethylenepentamine and adsorption study for anionic dye removal.

  Carbohydrate research 20110715

• Carbon dioxide capture by functionalized solid amine sorbents with simulated flue gas conditions.

  Environmental science & technology 20110701

• Novel phenol capturer derived from the as-synthesized MCM-41.

  Journal of hazardous materials 20110615

• Dicetyl phosphate-tetraethylenepentamine-based liposomes for systemic siRNA delivery.

  Bioconjugate chemistry 20110316

• Short-term exposure of umbilical cord blood CD34+ cells to granulocyte-macrophage colony-stimulating factor early in culture improves ex vivo expansion of neutrophils.

  Cytotherapy 20110301

• Adsorption of CO2 from flue gas streams by a highly efficient and stable aminosilica adsorbent.

  Journal of the Air & Waste Management Association (1995) 20110201

• In vitro characterization of two novel biodegradable vectors for the delivery of radiolabeled antisense oligonucleotides.

  Cancer biotherapy & radiopharmaceuticals 20101201

• Preparation of polyamine-functionalized copper specific adsorbents for selective adsorption of copper.

  Colloids and surfaces. B, Biointerfaces 20100701

• A new capillary electrophoresis buffer for determining organic and inorganic anions in electroplating bath with surfactant additives.

  Journal of chromatography. A 20100507

• Utilization of rice husk ash as silica source for the synthesis of mesoporous silicas and their application to CO2 adsorption through TREN/TEPA grafting.

  Journal of hazardous materials 20100315

• Poly(methyl methacrylate)-graft-oligoamines as low cytotoxic and efficient nonviral gene vectors.

  Molecular bioSystems 20100101

• A highly sensitive probe detecting low pH area of HeLa cells based on rhodamine B modified beta-cyclodextrins.

  Bioorganic & medicinal chemistry 20090815

• Chitosan based oligoamine polymers: synthesis, characterization, and gene delivery.

  Journal of controlled release : official journal of the Controlled Release Society 20090701

• Role for copper in the cellular and regulatory effects of heme-hemopexin.

  Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20090601

• Copper modulates the differentiation of mouse hematopoietic progenitor cells in culture.

  Cell transplantation 20090101

• Synthesis of magnetic chelating resins functionalized with tetraethylenepentamine for adsorption of molybdate anions from aqueous solutions.

  Journal of hazardous materials 20080630

• Transplantation of ex vivo expanded cord blood cells using the copper chelator tetraethylenepentamine: a phase I/II clinical trial.

  Bone marrow transplantation 20080501

• The effect of the copper chelator tetraethylenepentamine on reactive oxygen species generation by human hematopoietic progenitor cells.

  Stem cells and development 20071201

• Profiling preparations of recombinant birch pollen allergen Bet v 1a with capillary zone electrophoresis in pentamine modified fused-silica capillaries.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060724

• Chelatable cellular copper modulates differentiation and self-renewal of cord blood-derived hematopoietic progenitor cells.

  Experimental hematology 20051001

• Mitochondrial membrane potential is reduced in copper-deficient C2C12 cells in the absence of apoptosis.

  Biological trace element research 20050701

• NGF promotes copper accumulation required for optimum neurite outgrowth and protein methylation.

  Journal of neurobiology 20050401

• Linear polyamine copper chelator tetraethylenepentamine augments long-term ex vivo expansion of cord blood-derived CD34+ cells and increases their engraftment potential in NOD/SCID mice.

  Experimental hematology 20040601

• The effect of tetraethylenepentamine, a synthetic copper chelating polyamine, on expression of CD34 and CD38 antigens on normal and leukemic hematopoietic cells.

  Leukemia & lymphoma 20040301

• Pre-clinical development of cord blood-derived progenitor cell graft expanded ex vivo with cytokines and the polyamine copper chelator tetraethylenepentamine.

  Cytotherapy 20040101

• Analysis of organic acids and inorganic anions in beverage drinks by capillary electrophoresis.

  Electrophoresis 20030901

• Cellular copper content modulates differentiation and self-renewal in cultures of cord blood-derived CD34+ cells.

  British journal of haematology 20020301

• Inhibitors and specificity of Pseudomonas aeruginosa LasA.

  The Journal of biological chemistry 19970411