497-23-4 | 2(5H)-Furanone

Packsize	Purity	Availability	Price	Discounted Price
1g	97%	in stock	$7.00	$5.00
5g	97%	in stock	$10.00	$7.00
25g	97%	in stock	$27.00	$19.00
100g	97%	in stock	$102.00	$71.00
500g	97%	in stock	$505.00	$354.00

Description

• Catalog Number: AB49383
• Chemical Name: 2(5H)-Furanone
• CAS Number: 497-23-4
• Molecular Formula: C4H4O2
• Molecular Weight: 84.0734
• MDL Number: MFCD00005376
• SMILES: C1OC(=O)C=C1

Computed Properties

• Complexity: 93.7
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 6
• Hydrogen Bond Acceptor Count: 2
• XLogP3: -0.6

Literature

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  Journal of agricultural and food chemistry 20091028

• Total synthesis of oidiodendrolides and related norditerpene dilactones from a common precursor: metabolites CJ-14,445, LL-Z1271gamma, oidiolactones A, B, C, and D, and nagilactone F.

  Organic letters 20091015

• In ovo exposure of a Fusarium mycotoxin butenolide induces hepatic and renal oxidative damage in chick embryos, and antioxidants provide protections.

  Toxicology in vitro : an international journal published in association with BIBRA 20091001

• Concise syntheses of the natural products (+)-sylvaticin and (+)-cis-sylvaticin.

  Journal of the American Chemical Society 20090909

• Enzymatic kinetic resolution of primary allenic alcohols. Application to the total synthesis and stereochemical assignment of striatisporolide A.

  Organic & biomolecular chemistry 20090907

• A new class of conjugated strigolactone analogues with fluorescent properties: synthesis and biological activity.

  Organic & biomolecular chemistry 20090907

• Cycloaddition and one-carbon homologation studies in the synthesis of advanced iridoid precursors.

  Organic & biomolecular chemistry 20090907

• Synthesis and evaluation of pyrrolin-2-one compounds, a series of plasminogen activator inhibitor-1 inhibitors.

  Chemical & pharmaceutical bulletin 20090901

• Microbial reactions on 7alpha-hydroxyfrullanolide and evaluation of biotransformed products for antibacterial activity.

  Chemistry & biodiversity 20090901

• Synthesis of functionalized alpha-pyrone and butenolide derivatives by rhodium-catalyzed oxidative coupling of substituted acrylic acids with alkynes and alkenes.

  The Journal of organic chemistry 20090821

• Synthesis of all possible isomers corresponding to the proposed structure of montanacin E, and their antitumor activity.

  The Journal of organic chemistry 20090821

• Induction of abasic sites by the drinking-water mutagen MX in Salmonella TA100.

  Chemico-biological interactions 20090814

• Synthesis of new chiral 2,5-disubstituted 1,3,4-thiadiazoles possessing gamma-butenolide moiety and preliminary evaluation of in vitro anticancer activity.

  European journal of medicinal chemistry 20090801

• N-{4-Bromo-2-[(S)-menth-yloxy]-5-oxo-2,5-dihydro-3-fur-yl}-l-valine.

  Acta crystallographica. Section E, Structure reports online 20090801

• Calixpyrrole derivatives: 'multi hydrogen bond' catalysts for gamma-butenolide synthesis.

  Molecules (Basel, Switzerland) 20090715

• Covalent immobilization of antibacterial furanones via photochemical activation of perfluorophenylazide.

  Langmuir : the ACS journal of surfaces and colloids 20090707

• [A convenient synthesis of furans using bromacetyl-pyran-2-one].

  Die Pharmazie 20090701

• Three adducts of butenolide and apigenin glycoside from the leaves of Machilus japonica.

  Journal of natural products 20090701

• N-[(2S)-4-Chloro-2-(l-menth-yloxy)-5-oxo-2,5-dihydro-furan-3-yl]-l-valine.

  Acta crystallographica. Section E, Structure reports online 20090701

• Asymmetric total synthesis of pyranicin.

  Organic letters 20090618

• Synthesis of 5,5-disubstituted butenolides based on a Pd-catalyzed gamma-arylation strategy.

  Organic letters 20090618

• A short and practical synthesis of two Hagen's gland lactones.

  Carbohydrate research 20090612

• Enantioselective synthesis of chiral allenoates by guanidine-catalyzed isomerization of 3-alkynoates.

  Journal of the American Chemical Society 20090603

• Synthesis and pharmacological evaluation of 2(3H)-furanones and 2(3H)-pyrrolones, combining analgesic and anti-inflammatory properties with reduced gastrointestinal toxicity and lipid peroxidation.

  European journal of medicinal chemistry 20090601

• Antitumor compounds from marine actinomycetes.

  Marine drugs 20090601

• Cytotoxic and HIF-1alpha inhibitory compounds from Crossosoma bigelovii.

  Journal of natural products 20090522

• Total synthesis of ouabagenin and ouabain.

  Chemistry, an Asian journal 20090504

• N-[(2S)-4-Chloro-2-(l-menthyloxy)-5-oxo-2,5-dihydro-3-furyl]-l-alanine.

  Acta crystallographica. Section E, Structure reports online 20090501

• Direct asymmetric Michael addition to nitroalkenes: vinylogous nucleophilicity under dinuclear zinc catalysis.

  Journal of the American Chemical Society 20090408

• Repeated administration of a Fusarium mycotoxin butenolide to rats induces hepatic lipid peroxidation and antioxidant defense impairment.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090301

• Allantofuranone, a new antifungal antibiotic from Allantophomopsis lycopodina IBWF58B-05A.

  The Journal of antibiotics 20090301

• Butenolide induced cytotoxicity by disturbing the prooxidant-antioxidant balance, and antioxidants partly quench in human chondrocytes.

  Toxicology in vitro : an international journal published in association with BIBRA 20090201

• Basal expression of metallothionein suppresses butenolide-induced oxidative stress in liver homogenates in vitro.

  Toxicon : official journal of the International Society on Toxinology 20090201

• Novel experimental Pseudomonas aeruginosa lung infection model mimicking long-term host-pathogen interactions in cystic fibrosis.

  APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20090201

• Effects of Fusarium mycotoxin butenolide on myocardial mitochondria in vitro.

  Toxicology mechanisms and methods 20090201

• Chemistry and structural determination of botcinolides, botcinins, and botcinic acids.

  Chemical communications (Cambridge, England) 20090128

• Synthesis of casuarine-related derivatives via 1,3-dipolar cycloaddition between a cyclic nitrone and an unsaturated gamma-lactone.

  Carbohydrate research 20090126

• Stereoselective rhodium-catalyzed conjugate addition of boronic acids to unprotected delta-hydroxy-gamma-butenolides. Synthesis of (-)-7-oxamuricatacin and beta-substituted derivatives.

  The Journal of organic chemistry 20090102

• Trichothecenes in cereal grains.

  International journal of molecular sciences 20090101

• Optimal tuning of bacterial sensing potential.

  Molecular systems biology 20090101

• 2(3H)-furanones and 2(3H)-pyrrolones: synthesis and antimycobacterial evaluation.

  Acta poloniae pharmaceutica 20090101

• Photochemical key steps in the synthesis of surfactants from furfural-derived intermediates.

  ChemSusChem 20090101

• AI-2 does not function as a quorum sensing molecule in Campylobacter jejuni during exponential growth in vitro.

  BMC microbiology 20090101

• Stereochemical study of a novel tautomeric furanone, homofuraneol.

  Chirality 20090101

• Biofilm formation and acyl homoserine lactone production in Hafnia alvei isolated from raw milk.

  Biological research 20090101

• 7-Methyl-9-p-tolyl-4,9-dihydro-furo[3,4-b]quinolin-1(3H)-one.

  Acta crystallographica. Section E, Structure reports online 20090101

• Lipid peroxidation and antioxidant defense impairment in the hearts of chick embryos induced by in ovo exposure to Fusarium mycotoxin butenolide.

  Toxicon : official journal of the International Society on Toxinology 20081201

• Inhibition of Lux quorum-sensing system by synthetic N-acyl-L-homoserine lactone analogous.

  Acta biochimica et biophysica Sinica 20081201

• Antimycobacterial butanolides from the root of Lindera akoensis.

  Chemistry & biodiversity 20081201

• Efficient synthesis of 3-chloromethyl-2(5H)-furanones and 3-chloromethyl-5,6-dihydropyran-2-ones via the PdCl2-catalyzed chlorocyclocarbonylation of 2,3- or 3,4-allenols.

  The Journal of organic chemistry 20081121

• A concise and modular synthesis of pyranicin.

  Organic letters 20081106

• General, regiodefined access to alpha-substituted butenolides through metal-halogen exchange of 3-bromo-2-silyloxyfurans. Efficient synthesis of an anti-inflammatory gorgonian lipid.

  The Journal of organic chemistry 20081017

• Synthesis of 5-(1-H or 1-alkyl-5-oxopyrrolidin-3-yl)-8-hydroxy-[1,6]-naphthyridine-7-carboxamide inhibitors of HIV-1 integrase.

  Bioorganic & medicinal chemistry letters 20081001

• Neuropharmacology.

  Indian journal of pharmacology 20081001

• Formation of gamma-lactones through CAN-mediated oxidative cleavage of hemiketals.

  The Journal of organic chemistry 20080919

• A smoke-derived butenolide alleviates HgCl2 and ZnCl2 inhibition of water uptake during germination and subsequent growth of tomato--possible involvement of aquaporins.

  Journal of plant physiology 20080908

• Furanone derivatives as quorum-sensing antagonists of Pseudomonas aeruginosa.

  Applied microbiology and biotechnology 20080801

• Photochemical cycloaddition of mono-, 1,1-, and 1,2-disubstituted olefins to a chiral 2(5H)-furanone. Diastereoselective synthesis of (+)-lineatin.

  The Journal of organic chemistry 20080801

• 1-(2-Furo-yl)-3-(o-tol-yl)thio-urea.

  Acta crystallographica. Section E, Structure reports online 20080801

• Sugars containing alpha,beta-unsaturated carbonyl systems: synthesis and their usefulness as scaffolds in carbohydrate chemistry.

  Carbohydrate research 20080721

• Efficient conversion of carbohydrates into 1-C-alditols: application to the synthesis of chiral gamma-substituted butenolides and bicyclic alkaloid analogues.

  The Journal of organic chemistry 20080718

• Chemical composition and inhibitory parameters of essential oil and extracts of Nandina domestica Thunb. to control food-borne pathogenic and spoilage bacteria.

  International journal of food microbiology 20080715

• 1-(3-Cyano-phen-yl)-3-(2-furo-yl)thio-urea.

  Acta crystallographica. Section E, Structure reports online 20080701

• Total synthesis of cis-sylvaticin.

  Organic letters 20080619

• Dynamic function of the spacer region of acetogenins in the inhibition of bovine mitochondrial NADH-ubiquinone oxidoreductase (complex I).

  Biochemistry 20080610

• Direct catalytic asymmetric Mannich-type reactions of gamma-butenolides: effectiveness of Brønsted acid in chiral metal catalysis.

  Organic letters 20080605

• Detection of fungal development in closed spaces through the determination of specific chemical targets.

  Chemosphere 20080501

• Carbonylative polymerization of oxetanes initiated by acetyl cobalt complexes.

  Chemistry, an Asian journal 20080407

• A simple chemical method for synthesizing malonyl hemiesters of 21-hydroxypregnanes, potential intermediates in cardenolide biosynthesis.

  Steroids 20080401

• Novel lanostane and rearranged lanostane-type triterpenoids from Abies sachalinensis - II -.

  Chemical & pharmaceutical bulletin 20080401

• Total synthesis of (+)- and (-)-sundiversifolide via intramolecular acylation and determination of the absolute configuration.

  Organic letters 20080320

• Diastereoselective cyclopropanation of ketone enols with Fischer carbene complexes.

  Journal of the American Chemical Society 20080305

• Botryolides A-E, decarestrictine analogues from a fungicolous Botryotrichum sp. (NRRL 38180).

  Journal of natural products 20080301

• The function of SpnR and the inhibitory effects by halogenated furanone on quorum sensing in Serratia marcescens AS-1.

  Wei sheng wu xue bao = Acta microbiologica Sinica 20080301

• Total synthesis of (+)-achalensolide based on the rh(i)-catalyzed allenic Pauson-Khand-type reaction.

  The Journal of organic chemistry 20080201

• Identifying the important structural elements of brominated furanones for inhibiting biofilm formation by Escherichia coli.

  Bioorganic & medicinal chemistry letters 20080201

• Pyranicin, a non-classical annonaceous acetogenin, is a potent inhibitor of DNA polymerase, topoisomerase and human cancer cell growth.

  International journal of oncology 20080201

• Insect growth regulatory effects of linear diterpenoids and derivatives from Baccharis thymifolia.

  Journal of natural products 20080201

• TOF-SIMS and principal component analysis characterization of the multilayer surface grafting of small molecules: antibacterial furanones.

  Analytical chemistry 20080115

• Two new Monascus metabolites with strong blue fluorescence isolated from red yeast rice.

  Journal of agricultural and food chemistry 20080109

• Synthesis and optical resolution of an allenoic acid by diastereomeric salt formation induced by chiral alkaloids.

  Chirality 20080101

• Novel abietane diterpenoids and aromatic compounds from Cladonia rangiferina and their antimicrobial activity against antibiotics resistant bacteria.

  Chemical & pharmaceutical bulletin 20080101

• Interactions between chromophore and protein in phytochrome identified by novel oxa-, thia- and carba-chromophores.

  Photochemistry and photobiology 20080101

• LuxS-independent formation of AI-2 from ribulose-5-phosphate.

  BMC microbiology 20080101

• Cyclophane-type imidazolium salts with planar chirality as a new class of N-heterocyclic carbene precursors.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20080101

• Ruthenium-catalyzed carbonylative cycloaddition reactions involving carbonyl and imino groups as assembling units.

  Chemical record (New York, N.Y.) 20080101

• Total synthesis of naturally configured pyrrhoxanthin, a carotenoid butenolide from plankton.

  Angewandte Chemie (International ed. in English) 20080101

• Cinnamaldehyde and cinnamaldehyde derivatives reduce virulence in Vibrio spp. by decreasing the DNA-binding activity of the quorum sensing response regulator LuxR.

  BMC microbiology 20080101

• Lack of genomic evidence of AI-2 receptors suggests a non-quorum sensing role for luxS in most bacteria.

  BMC microbiology 20080101

• Antiproliferative compounds of Artabotrys madagascariensis from the Madagascar rainforest.

  Natural product research 20080101

• Bioactivity and chemistry of the genus Hortonia.

  Natural product research 20080101

• Recent progress on the total synthesis of acetogenins from Annonaceae.

  Beilstein journal of organic chemistry 20080101

• Synthesis of a putative substrate for malonyl-coenzyme A: 21-hydroxypregnane 21-O-malonyltransferase and development of an HPLC method for the quantification of the enzyme reaction.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20071215

• Discovery of the apoptosis-inducing activity and high accumulation of the butenolides, menisdaurilide and aquilegiolide in Dicentra spectabilis.

  Planta medica 20071201

• New signaling molecules in some gram-positive and gram-negative bacteria.

  International journal of food microbiology 20071130

• Diastereoselective synthesis of glutamate-appended oxolane rings: synthesis of (s)-(+)-lycoperdic acid.

  The Journal of organic chemistry 20071123

• From genetic diversity to metabolic unity: studies on the biosynthesis of aurafurones and aurafuron-like structures in myxobacteria and streptomycetes.

  Journal of molecular biology 20071116

• Molecular biology of Fusarium mycotoxins.

  International journal of food microbiology 20071020

• Synthetic bromated furanone inhibits autoinducer-2-mediated communication and biofilm formation in oral streptococci.

  Oral microbiology and immunology 20071001

• The natural furanone (5Z)-4-bromo-5-(bromomethylene)-3-butyl-2(5H)-furanone disrupts quorum sensing-regulated gene expression in Vibrio harveyi by decreasing the DNA-binding activity of the transcriptional regulator protein luxR.

  Environmental microbiology 20071001

• Inhibitory effect of Egyptian propolis on Fasciola gigantica eggs with reference to its effect on Clostridium oedematiens and correlation to chemical composition.

  Pakistan journal of biological sciences : PJBS 20071001

• Structural basis of spirolactone recognition by the mineralocorticoid receptor.

  Molecular pharmacology 20070901

• Synthesis of novel antitumoural analogues of dysidiolide from ent-halimic acid.

  Bioorganic & medicinal chemistry 20070901

• Toxic effects of Fusarium mycotoxin butenolide on rat myocardium and primary culture of cardiac myocytes.

  Toxicon : official journal of the International Society on Toxinology 20070901

• Structural and mechanistic basis of penicillin-binding protein inhibition by lactivicins.

  Nature chemical biology 20070901

• Bacterial communications in implant infections: a target for an intelligence war.

  The International journal of artificial organs 20070901

• Two new butenolide derivatives from Saussurea katochaete.

  Die Pharmazie 20070901

• Copper-catalyzed methylenation reaction: total synthesis of (+)-desoxygaliellalactone.

  Organic letters 20070830

• Easy and stereoselective approach to alpha,beta-unsaturated gamma-lactones fused to pyranoses from furanose scaffolds.

  Organic letters 20070816

• Fluoride-assisted regioselective conversion of functionalized furans to alpha-substituted gamma-hydroxybutenolides using singlet oxygen.

  The Journal of organic chemistry 20070803

• The oxidative damage of butenolide to isolated erythrocyte membranes.

  Toxicology in vitro : an international journal published in association with BIBRA 20070801

• Phellinone, a new furanone derivative from the Phellinus linteus KT&G PL-2.

  Archives of pharmacal research 20070801

• Stereoselective route to oxetanocin carbocyclic analogues based on a [2 + 2] photocycloaddition to a chiral 2(5H)-furanone.

  Organic letters 20070719

• Prooxidant action of furanone compounds: implication of reactive oxygen species in the metal-dependent strand breaks and the formation of 8-hydroxy-2'-deoxyguanosine in DNA.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20070701

• Mechanism of the ring contraction process in vitamin B12 biosynthesis by the anaerobe Propionibacterium shermanii under aerobic conditions.

  The FEBS journal 20070701

• Interference with the quorum sensing systems in a Vibrio harveyi strain alters the growth rate of gnotobiotically cultured rotifer Brachionus plicatilis.

  Journal of applied microbiology 20070701

• Stereoselective iodocyclization of (S)-allylalanine derivatives: gamma-lactone vs cyclic carbamate formation.

  Organic letters 20070607

• The ND1 subunit constructs the inhibitor binding domain in bovine heart mitochondrial complex I.

  Biochemistry 20070529

• Design and total synthesis of unnatural analogues of the sub-nanomolar SERCA inhibitor thapsigargin.

  Organic & biomolecular chemistry 20070507

• Vibrational spectra, ab initio calculations, and ring-puckering potential energy function for gamma-crotonolactone.

  The journal of physical chemistry. A 20070503

• Withanolides with phytotoxic activity from Jaborosa caulescens var. caulescens and J. caulescens var. bipinnatifida 1.

  Journal of natural products 20070501

• Rhizobialide: a new stearolactone produced by Mesorhizobium sp. CCNWGX022, a rhizobial endophyte from Glycyrrhiza uralensis.

  Chemistry & biodiversity 20070501

• Novel synthons from mucochloric acid: the first use of alpha,beta-dichloro-gamma-butenolides and gamma-butyrolactams for direct vinylogous aldol addition.

  The Journal of organic chemistry 20070427

• A novel gene cluster in Fusarium graminearum contains a gene that contributes to butenolide synthesis.

  Fungal genetics and biology : FG & B 20070401

• Antiplasmodial hirsutinolides from Vernonia staehelinoides and their utilization towards a simplified pharmacophore.

  Phytochemistry 20070401

• [Butenolide induces apoptosis of cultured chondrocytes: study of its mechanism].

  Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20070401

• Studies on the synthesis of (-)-gymnodimine. Subunit synthesis and coupling.

  The Journal of organic chemistry 20070302

• A new 2,3-dimethyl butenolide from the brittle star Ophiomastix mixta.

  Chemical & pharmaceutical bulletin 20070301

• [Application of HATR-FTIR spectroscopy to the analysis of quality mensuration of rhizoma Atractylodes].

  Guang pu xue yu guang pu fen xi = Guang pu 20070201

• Butenolide synthesis by molybdenum-mediated hetero-pauson-khand reaction of alkynyl aldehydes.

  Journal of the American Chemical Society 20070131

• Influence of epicatechin reactions on the mechanisms of Maillard product formation in low moisture model systems.

  Journal of agricultural and food chemistry 20070124

• Ti-direct, powerful, stereoselective aldol-type additions of esters and thioesters to carbonyl compounds: application to the synthesis and evaluation of lactone analogs of jasmone perfumes.

  Organic & biomolecular chemistry 20070107

• Total synthesis and evaluation of the actin-binding properties of microcarpalide and a focused library of analogues.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20070101

• Effects of the short chain sugar acid 2-buten-4-olide on the hypothalamo-pituitary-adrenal axis in normal and adjuvant-induced arthritic rats.

  Journal of neuroendocrinology 20070101

• Effects of plant lactones on the production of biofilm of Pseudomonas aeruginosa.

  Chemical & pharmaceutical bulletin 20070101

• E/Z-rubrolide O, an anti-inflammatory halogenated furanone from the New Zealand ascidian Synoicum n. sp.

  Journal of natural products 20070101

• Unifying mechanism for bacterial cell signalers (4,5-dihydroxy-2,3-pentanedione, lactones and oligopeptides): electron transfer and reactive oxygen species. Practical medical features.

  Medical hypotheses 20070101

• Pyruvate aldolases in chiral carbon-carbon bond formation.

  Nature protocols 20070101

• Toxicogenomic analysis incorporating operon-transcriptional coupling and toxicant concentration-expression response: analysis of MX-treated Salmonella.

  BMC bioinformatics 20070101

• Regiocontrolled intramolecular cyclizations of carboxylic acids to carbon-carbon triple bonds promoted by acid or base catalyst.

  Organic letters 20061123

• Divergent synthetic strategy leading to structurally diverse pyrrolidines and piperidines from common gamma-aminoalkyl butenolide and aldehyde precursors.

  The Journal of organic chemistry 20061110

• A highly efficient and practical method for catalytic asymmetric vinylogous Mannich (AVM) reactions.

  Angewandte Chemie (International ed. in English) 20061106

• A new gamma-lactone from the leaves of Cinnamomum kotoense.

  Natural product research 20061101

• 13C NMR-based empirical rules to determine the configuration of fatty acid butanolides. Novel gamma-dilactones from Pterogorgia spp.

  Organic letters 20061026

• Enzyme ribonucleotide reductase: unraveling an enigmatic paradigm of enzyme inhibition by furanone derivatives.

  The journal of physical chemistry. B 20061026

• Characterization of volatiles in extracts from oak chips obtained by accelerated solvent extraction (ASE).

  Journal of agricultural and food chemistry 20061018

• Regioselective entry to bromo-gamma-hydroxybutenolides: useful building blocks for assemblying natural product-like libraries.

  Organic letters 20061012

• Ozone's impact on public health: contributions from indoor exposures to ozone and products of ozone-initiated chemistry.

  Environmental health perspectives 20061001

• Constituents of the roots of Pueraria lobata inhibit formation of advanced glycation end products (AGEs).

  Archives of pharmacal research 20061001

• The Stille reaction in the synthesis of the C37-norcarotenoid butenolide pyrrhoxanthin. Scope and limitations.

  The Journal of organic chemistry 20060804

• Convergent synthesis of pyragonicin.

  The Journal of organic chemistry 20060804

• Major secondary metabolites produced by two commercial Trichoderma strains active against different phytopathogens.

  Letters in applied microbiology 20060801

• Total syntheses of (+)-1893B and its three diastereomers and evaluation of their biological activities.

  The Journal of antibiotics 20060801

• Depletion of intracellular glutathione mediates butenolide-induced cytotoxicity in HepG2 cells.

  Toxicology letters 20060714

• Diastereoselective, vinylogous mukaiyama aldol additions of silyloxy furans to cyclic ketones: annulation of butenolides and gamma-lactones.

  Organic letters 20060706

• [Quorum sensing: a new clinical target for Pseudomonas aeruginosa?].

  Medecine et maladies infectieuses 20060701

• Difference in the volatile composition of pine-mushrooms (Tricholoma matsutake Sing.) according to their grades.

  Journal of agricultural and food chemistry 20060628

• [Toxic effect of butenolide on chondrocyte differentiation and the protective effect of selenium].

  Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20060601

• Novel anti-bacterials against MRSA: synthesis of focussed combinatorial libraries of tri-substituted 2(5H)-furanones.

  Current drug discovery technologies 20060601

• The short chain sugar acid, 2-buten-4-olide, activates oxytocin-secreting neurons but not arginine vasopressin-secreting neurons in the hypothalamus of rats.

  Brain research 20060501

• Solution-phase parallel synthesis with oligoethylene glycol sorting tags. Preparation of all four stereoisomers of the hydroxybutenolide fragment of murisolin and related acetogenins.

  The Journal of organic chemistry 20060428

• New peanut (Arachis hypogaea) phytoalexin with prenylated benzenoid and but-2-enolide moieties.

  Journal of agricultural and food chemistry 20060322

• Divergence en route to nonclassical annonaceous acetogenins. Synthesis of pyranicin and pyragonicin.

  The Journal of organic chemistry 20060303

• New Monascus metabolites: structure elucidation and toxicological properties studied with immortalized human kidney epithelial cells.

  Molecular nutrition & food research 20060301

• Isolation and identification of three new 5-alkenyl-3,3(2H)-furanones from two streptomyces species using a genomic screening approach.

  The Journal of antibiotics 20060301

• Heterocyclic analogues of squamocin as inhibitors of mitochondrial complex I. On the role of the terminal lactone of annonaceous acetogenins.

  Biochemistry 20060227

• Utilization of a 1,2-dioxine for the synthesis of the four possible stereoisomers of oak lactone.

  Organic letters 20060202

• Synthesis and conformational analysis of new cyclobutane-fused nucleosides.

  Organic letters 20060202

• Up- and down-regulation of Fragaria x ananassa O-methyltransferase: impacts on furanone and phenylpropanoid metabolism.

  Journal of experimental botany 20060101

• Clustering of Pseudomonas aeruginosa transcriptomes from planktonic cultures, developing and mature biofilms reveals distinct expression profiles.

  BMC genomics 20060101

• Furanones.

  Progress in molecular and subcellular biology 20060101

• Solid-phase synthesis of substituted butenolides and butyrolactones using a traceless sulfone linker.

  Journal of combinatorial chemistry 20060101

• Heteroatom-guided torquoselective olefination of alpha-oxy and alpha-amino ketones via ynolates.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20051223

• Synthesis, structure, and reactivity of unexpectedly stable spiroepoxy-beta-lactones obtained by epoxidation of 4-alkylidene-2-oxetanones.

  Journal of the American Chemical Society 20051207

• Tandem au-catalyzed 3,3-rearrangement-[2 + 2] cycloadditions of propargylic esters: expeditious access to highly functionalized 2,3-indoline-fused cyclobutanes.

  Journal of the American Chemical Society 20051207

• Anti-inflammatory effects of indomethacin's methyl ester derivative and induction of apoptosis in HL-60 Cells.

  Biological & pharmaceutical bulletin 20051201

• Dynamic function of the alkyl spacer of acetogenins in their inhibitory action with mitochondrial complex I (NADH-ubiquinone oxidoreductase).

  Biochemistry 20051115

• Biological activities of retinoidal gamma-hydroxybutenolides in cancer cell apoptosis and differentiation.

  Bioorganic & medicinal chemistry 20051101

• Progress in the synthesis of the lituarines: stereocontrol in sequential C-C bond formation on a spirobutenolide template.

  Organic letters 20051027

• Total synthesis of murisolins and evaluation of tumor-growth inhibitory activity.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20051021

• Total synthesis of milbemycins: a synthesis of (6R)-6-hydroxy-3,4-dihydromilbemycin E.

  Organic & biomolecular chemistry 20051021

• A total synthesis of milbemycin G: approaches to the C1-C10-fragment and completion of the synthesis.

  Organic & biomolecular chemistry 20051021

• Uncatalyzed Mukaiyama-Michael reaction: rapid access to simple and complex enantiopure gamma-butenolides.

  Angewandte Chemie (International ed. in English) 20051014

• A novel total synthesis of kinsenoside and goodyeroside A relying on the efficient reaction of the chiral 2(5H)-furanones.

  Journal of Asian natural products research 20051001

• Mechanism of the solution oxidation of rofecoxib under alkaline conditions.

  Pharmaceutical research 20051001

• Stereocontrolled total synthesis of (-)-kainic acid. Regio- and stereoselective lithiation of pyrrolidine ring with the (+)-sparteine surrogate.

  Organic letters 20050929

• Total synthesis and structural confirmation of (+)-longicin.

  Organic letters 20050901

• Facile synthesis of beta-organotellurobutenolides via electrophilic tellurolactonization of alpha-allenoic acids.

  The Journal of organic chemistry 20050819

• Chromium(III) octaethylporphyrinato tetracarbonylcobaltate: a highly active, selective, and versatile catalyst for epoxide carbonylation.

  Journal of the American Chemical Society 20050817

• Oxidative cyclization reactions: amide trapping groups and the synthesis of furanones.

  Organic letters 20050804

• Rh(I)-catalyzed CO gas-free cyclohydrocarbonylation of alkynes with formaldehyde to alpha,beta-butenolides.

  Chemical communications (Cambridge, England) 20050714

• Inhibition of Bacillus anthracis growth and virulence-gene expression by inhibitors of quorum-sensing.

  The Journal of infectious diseases 20050601

• Novel approach to pro-drugs of lactones: water soluble imidate and ortho-ester derivatives of a furanone-based COX-2 selective inhibitor.

  Bioorganic & medicinal chemistry letters 20050502

• Sesquiterpenes and butenolides, natural anti-HIV constituents from Litsea verticillata.

  Planta medica 20050501

• Pd(II)-catalyzed oxidative dimeric cyclization-coupling reaction of 2,3-allenoic acids: an efficient synthesis of bibutenolide derivatives.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20050408

• Kinetic resolution and chemoenzymatic dynamic kinetic resolution of functionalized gamma-hydroxy amides.

  The Journal of organic chemistry 20050401

• Calbistrin E and two other new metabolites from an Australian isolate of Penicillium striatisporum.

  Journal of natural products 20050401

• Enantioselective syntheses and configuration assignments of gamma-chiral butenolides from Plagiomnium undulatum: butenolide synthesis from tetronic acids.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20050318

• Selective detection of 2-deoxyribonolactone in DNA.

  Journal of the American Chemical Society 20050309

• Quorum-sensing antagonist (5Z)-4-bromo-5-(bromomethylene)-3-butyl-2(5H)-furanone influences siderophore biosynthesis in Pseudomonas putida and Pseudomonas aeruginosa.

  Applied microbiology and biotechnology 20050301

• Anti-tuberculosis constituents from the stem bark of Micromelum hirsutum.

  Planta medica 20050301

• Communiols E-H: new polyketide metabolites from the coprophilous fungus Podospora communis.

  Journal of natural products 20050301

• Effects of quorum sensing molecules of Pseudomonas aeruginosa on organism growth, elastase B production, and primary adhesion to hydrogel contact lenses.

  Eye & contact lens 20050301

• Novel strategy for the synthesis of the butenolide moiety of peridinin.

  Angewandte Chemie (International ed. in English) 20050225

• The Stille reaction in the synthesis of carotenoid butenolides: synthesis of 6'-epi-peridinin.

  Organic letters 20050217

• Biomimetic total synthesis of (+)-himbacine.

  Organic letters 20050217

• I(-)-catalyzed methyl-oxygen bond cleavage in 2-methoxyfurans. An efficient synthesis of butenolides.

  The Journal of organic chemistry 20050204

• Relation of trihalomethane concentrations in public water supplies to stillbirth and birth weight in three water regions in England.

  Environmental health perspectives 20050201

• 2,3-di-O-methoxymethyl-6-O-tert-butyldimethylsilyl-gamma-cyclodextrin: a new class of cyclodextrin derivatives for gas chromatographic separation of enantiomers.

  Journal of chromatography. A 20050121

• Total synthesis of pyranicin.

  Organic letters 20050120

• A gamma-lactone form nafuredin, nafuredin-gamma, also inhibits helminth complex I.

  The Journal of antibiotics 20050101

• New modification of the Perkow reaction: halocarboxylate anions as leaving groups in 3-acyloxyquinoline-2,4(1H,3H)-dione compounds.

  Beilstein journal of organic chemistry 20050101

• Dimerization of butenolide structures. A biomimetic approach to the dimeric sesquiterpene lactones (+/-)-biatractylolide and (+/-)-biepiasterolide.

  The Journal of organic chemistry 20041224

• Selenium-catalyzed halolactonization: nucleophilic activation of electrophilic halogenating reagents.

  The Journal of organic chemistry 20041210

• Regio- and stereoselective construction of gamma-butenolides through phosphine-catalyzed substitution of Morita-Baylis-Hillman acetates: an organocatalytic allylic alkylation.

  Angewandte Chemie (International ed. in English) 20041210

• Differential gene expression shows natural brominated furanones interfere with the autoinducer-2 bacterial signaling system of Escherichia coli.

  Biotechnology and bioengineering 20041205

• Accumulation of allo-isocitric acid by a Penicillium strain.

  The Journal of general and applied microbiology 20041201

• Stereoselective photochemical 1,3-dioxolane addition to 5-alkoxymethyl-2(5H)-furanone: synthesis of bis-tetrahydrofuranyl ligand for HIV protease inhibitor UIC-94017 (TMC-114).

  The Journal of organic chemistry 20041112

• Stereochemical features of Lewis acid-promoted glycosidations involving 4'-spiroannulated DNA building blocks.

  The Journal of organic chemistry 20041029

• Precise structural elucidation of dehydroaltenusin, a specific inhibitor of mammalian DNA polymerase alpha.

  Bioorganic & medicinal chemistry 20041015

• Absolute stereochemistry of acremolactone A, a novel herbicidal epoxydihydropyranyl gamma-lactone from Acremonium roseum I4267.

  Bioscience, biotechnology, and biochemistry 20041001

• Synthesis and determination of the absolute configuration of fugomycin and desoxyfugomycin: CD spectroscopy and fungicidal activity of butenolides.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20040920

• Furanones as potential anti-bacterial coatings on biomaterials.

  Biomaterials 20040901

• Biological performance of a novel synthetic furanone-based antimicrobial.

  Biomaterials 20040901

• Cytotoxicity of 3,4-dihalogenated 2(5H)-furanones.

  The Journal of pharmacy and pharmacology 20040901

• A compound from smoke that promotes seed germination.

  Science (New York, N.Y.) 20040813

• Structure and unexpected chiroptical properties of chiral 4-pyrrolidinyl substituted 2(5H)-furanones.

  Chirality 20040801

• Chemical communication in proteobacteria: biochemical and structural studies of signal synthases and receptors required for intercellular signalling.

  Molecular microbiology 20040801

• A concise synthesis of siphonodictidine.

  Journal of natural products 20040801

• Synthetic furanones inhibit quorum-sensing and enhance bacterial clearance in Pseudomonas aeruginosa lung infection in mice.

  The Journal of antimicrobial chemotherapy 20040601

• The first example of the stereoselective synthesis of 7 beta-carbamoyl-4,5alpha-epoxymorphinan via a novel and reactive gamma-lactone.

  Chemical & pharmaceutical bulletin 20040601

• Suzuki cross-coupling reactions of gamma-alkylidenebutenolides: application to the synthesis of vulpinic acid.

  The Journal of organic chemistry 20040528

• (5Z)-4-bromo-5-(bromomethylene)-3-butyl-2(5H)-furanone reduces corrosion from Desulfotomaculum orientis.

  Environmental microbiology 20040501

• Total synthesis of the nonadjacently linked bis-tetrahydrofuran acetogenin bullatanocin (squamostatin C).

  The Journal of organic chemistry 20040430

• Highly efficient and diastereoselective synthesis of (+)-lineatin.

  Organic letters 20040429

• Butenolides from a cultured microfungus, Acremonium sp.

  Natural product research 20040401

• Development of novel chiral urea catalysts for the hetero-Michael reaction.

  Chemical & pharmaceutical bulletin 20040401

• New beta-caryophyllene-derived terpenoids from the soft coral Sinularia nanolobata.

  Journal of natural products 20040401

• Zooxanthellactone, a novel gamma-lactone-type oxylipine from dinoflagellates of Symbiodinium sp.: structure, distribution, and biological activity.

  Bioscience, biotechnology, and biochemistry 20040401

• Synthesis and inhibitory action of novel acetogenin mimics with bovine heart mitochondrial complex I.

  Biochemistry 20040330

• Stereoselective approach to C-aryl pyranoside synthesis which addresses the problem of C7-substitution in blepharocalyxin E.

  The Journal of organic chemistry 20040319

• Further insights on the structural aspects of PLA(2) inhibition by gamma-hydroxybutenolide-containing natural products: a comparative study on petrosaspongiolides M-R.

  Bioorganic & medicinal chemistry 20040315

• Synthesis of gamma,delta-unsaturated and delta,epsilon-unsaturated alpha-amino acids from fragmentation of gamma- and delta-lactones.

  The Journal of organic chemistry 20040206

• Lambertellols A and B, novel 3,4-dihydronaphthalen-1(2H)-ones with spiro-butenolide produced by Lambertella sp.1346.

  Organic letters 20040122

• Plakolide A, a new gamma-lactone from the marine sponge Plakortis sp.

  Journal of natural products 20040101

• Analysis of Fusarium graminearum mycotoxins in different biological matrices by LC/MS.

  Mycopathologia 20040101

• Abilities of 3,4-diarylfuran-2-one analogs of combretastatin A-4 to inhibit both proliferation of tumor cell lines and growth of relevant tumors in nude mice.

  Anticancer research 20040101

• Effects of natural and chemically synthesized furanones on quorum sensing in Chromobacterium violaceum.

  BMC microbiology 20040101

• Sensitized photooxygenation of the fungicide furalaxyl.

  Environmental science and pollution research international 20040101

• Synthesis and supramolecular properties of conformationally restricted and flexible phospholipids.

  The Journal of organic chemistry 20031226

• Synthesis of the cyclobutanone core of solanoeclepin A intramolecular allene butenolide photocycloaddition.

  Organic & biomolecular chemistry 20031221

• Hydroperoxide and endoperoxide lactones from photooxygenation of 3-alkylidenedihydrofuran-2,4-diones.

  The Journal of organic chemistry 20031212

• Alpha-pyrones and a 2(5H)-furanone from Hyptis pectinata.

  Phytochemistry 20031201

• Novel alpha-pyrones produced by a marine Pseudomonas sp. F92S91: taxonomy and biological activities.

  The Journal of antibiotics 20031201

• Enantioselective synthesis of bicyclo[6.1.0]nonane-9-carboxylic acids via Me2AlOTf-promoted intramolecular Friedel-Crafts alkylation of arenes with the gamma-lactone moiety of 3-oxabicyclo[3.1.0]hexan-2-ones.

  The Journal of organic chemistry 20031128

• Inhibitory effects on mitochondrial complex I of semisynthetic mono-tetrahydrofuran acetogenin derivatives.

  Bioorganic & medicinal chemistry letters 20031117

• Physiological significance of 2-buten-4-olide (2-B4O), an endogenous satiety substance increased in the fasted state.

  Experimental biology and medicine (Maywood, N.J.) 20031101

• Enhancement of the antiplasmodial activity of quassin by transformation into a gamma-lactone.

  Journal of natural products 20031101

• Design, synthesis, and anticancer activity of phosphonic acid diphosphate derivative of adenine-containing butenolide and its water-soluble derivatives of paclitaxel with high antitumor activity.

  Bioorganic & medicinal chemistry 20031001

• Synthesis and evaluation of 5-arylated 2(5H)-furanones and 2-arylated pyridazin-3(2H)-ones as anti-cancer agents.

  The Journal of pharmacy and pharmacology 20030901

• New monascus metabolites with a pyridine structure in red fermented rice.

  Journal of agricultural and food chemistry 20030827

• Novel autoxidation and Michael addition of a butenolide-containing sugar leading to a C-branched-chain glucopyranosidulose, and X-ray structure of intermediates.

  Carbohydrate research 20030812

• Attenuation of Pseudomonas aeruginosa virulence by quorum sensing inhibitors.

  The EMBO journal 20030801

• Iridoids from Kigelia pinnata DC. fruits.

  Phytochemistry 20030801

• Synthesis and inhibitory activity of ubiquinone-acetogenin hybrid inhibitor with bovine mitochondrial complex I.

  Bioorganic & medicinal chemistry letters 20030721

• A GaCl3-catalyzed [4+1] cycloaddition of alpha,beta-unsaturated carbonyl compounds and isocyanides leading to unsaturated gamma-lactone derivatives.

  Journal of the American Chemical Society 20030702

• New taxane diterpenoids from Taiwanese Taxus sumatrana.

  Chemical & pharmaceutical bulletin 20030701

• A cytotoxic butenolide, two new dolabellane diterpenoids, a chroman and a benzoquinol derivative formosan Casearia membranacea.

  Planta medica 20030701

• Isolation and characterization of kallosin A, a novel rearranged pseudopterane diterpenoid from the Caribbean sea plume Pseudopterogorgia kallos (Bielschowsky).

  The Journal of organic chemistry 20030613

• First asymmetric synthesis of (-)-lintetralin via intramolecular Friedel-Crafts-type cyclization.

  Chirality 20030601

• Synthesis of phytuberin. 4-endo-tet acid-catalyzed cyclization of alpha-hydroxy epoxides.

  The Journal of organic chemistry 20030530

• Inhibitory activities of three annonaceous acetogenins on NADH oxidase of chicken liver mitochondria.

  Biological & pharmaceutical bulletin 20030501

• Total synthesis of a cytotoxic acetogenin, pyranicin.

  Organic letters 20030417

• Chalcogenide-Lewis acid mediated reactions of electron-deficient alkynes with aldehydes.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20030404

• Synthetic studies on himbacine, a potent antagonist of the muscarinic M2 subtype receptor. Part 2: synthesis and muscarinic M2 subtype antagonistic activity of the novel himbacine congeners modified at the C-3 position of lactone moiety.

  Bioorganic & medicinal chemistry 20030403

• C2-Symmetric enantiopure ethanotethered bis(alpha,beta-butenolides) as templates for asymmetric synthesis. Application to the synthesis of (+)-grandisol.

  The Journal of organic chemistry 20030321

• Palladium catalyzed kinetic and dynamic kinetic asymmetric transformations of gamma-acyloxybutenolides. Enantioselective total synthesis of (+)-Aflatoxin B1 and B2a.

  Journal of the American Chemical Society 20030312

• A modular synthesis of annonaceous acetogenins.

  The Journal of organic chemistry 20030307

• Total synthesis and structure confirmation of the annonaceous acetogenins 30(S)-hydroxybullatacin, uvarigrandin a, and 5(R)-uvarigrandin a (narumicin I?).

  The Journal of organic chemistry 20030307

• Efficient desymmetrization of 'pseudo'-C2-symmetric substrates: illustration in the synthesis of a disubstituted butenolide from arabitol.

  The Journal of organic chemistry 20030307

• Unprecedented reactivity of N-heterocyclic carbenes toward DMAD and aldehydes leading to novel multicomponent reactions.

  Organic letters 20030306

• Cross-linking of 2-deoxyribonolactone and its beta-elimination product by base excision repair enzymes.

  Biochemistry 20030304

• Two novel ravenelones from the edible mushroom Pulveroboletus ravenelii.

  Chemical & pharmaceutical bulletin 20030301

• The first enantioselective organocatalytic Mukaiyama-Michael reaction: a direct method for the synthesis of enantioenriched gamma-butenolide architecture.

  Journal of the American Chemical Society 20030205

• COX-2 and prostanoid expression in micturition pathways after cyclophosphamide-induced cystitis in the rat.

  American journal of physiology. Regulatory, integrative and comparative physiology 20030201

• Total synthesis of the antitumor acetogenin mosin B: desymmetrization approach to the stereodivergent synthesis of threo/trans/erythro-type acetogenins.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20030120

• Studies on mimicry of naturally occurring annonaceous acetogenins: non-THF analogues leading to remarkable selective cytotoxicity against human tumor cells.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20030103

• Effect of cyclooxygenase-2 (COX-2) inhibitors on prostate cancer cell proliferation.

  Anticancer research 20030101

• In vitro antitumor structure-activity relationships of threo/trans/threo mono-tetrahydrofuranic acetogenins: correlations with their inhibition of mitochondrial complex I.

  Oncology research 20030101

• NMR determination of absolute configuration of butenolides of annonaceous type.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20021216

• The effect of selective inhibition of cyclooxygenase (COX)-2 on acute cardiac allograft rejection.

  Transplantation 20021215

• Design, synthesis, and biological evaluation of a series of beta-lactam-based prodrugs.

  Bioorganic & medicinal chemistry 20021101

• De novo synthesis of 4'-ethoxy nucleoside analogues.

  The Journal of organic chemistry 20021101

• Dramatic rate enhancement with preservation of stereospecificity in the first metal-catalyzed additions of allylboronates.

  Journal of the American Chemical Society 20021002

• Synthesis and cytotoxicity of some rigid derivatives of methyl 2,5-dihydroxycinnamate.

  Archives of pharmacal research 20021001

• [Inhibition of oxygen consumption by annonaceous acetogenins in liver cell respiration and their structure-activity relationship].

  Yao xue xue bao = Acta pharmaceutica Sinica 20021001

• Intramolecular reaction of a phenonium ion. Novel lactonization of 4-aryl-5-tosyloxypentanoates and 4-aryl-5-tosyloxyhexanoates concomitant with a phenyl rearrangement.

  The Journal of organic chemistry 20020920

• Total synthesis of an antitumor agent, mucocin, based on the 'chiron approach'.

  The Journal of organic chemistry 20020809

• Chiral N-alkyl-2,4,6-triphenylpyridiniums as enantioselective triplet photosensitizers. laser flash photolysis and preparative studies.

  The Journal of organic chemistry 20020726

• New monascus metabolite isolated from red yeast rice (angkak, red koji).

  Journal of agricultural and food chemistry 20020703

• Synthesis of new azulene derivatives and study of their effect on lipid peroxidation and lipoxygenase activity.

  Chemical & pharmaceutical bulletin 20020701

• N-Substituted 4-amino-3,3-dipropyl-2(3H)-furanones: new positive allosteric modulators of the GABA(A) receptor sharing electrophysiological properties with the anticonvulsant loreclezole.

  Journal of medicinal chemistry 20020620

• The power of visual imagery in synthesis planning. Stereocontrolled approaches to CGP-60536B, a potent renin inhibitor.

  The Journal of organic chemistry 20020614

• Synthesis of indolizidines and pyrrolizidines through the [2 + 2]cycloaddition of five-membered endocyclic enecarbamates to alkyl ketenes. Unusual regioselectivity of Baeyer-Villiger ring expansions of alkyl aza-bicyclic cyclobutanones.

  The Journal of organic chemistry 20020531

• Oxidative cyclization-dimerization reaction of 2,3-allenoic acids and 1,2-allenyl ketones: an efficient synthesis of 4-(3'-furanyl)butenolide derivatives.

  Angewandte Chemie (International ed. in English) 20020517

• Maillard reaction of D-glucose: identification of a colored product with conjugated pyrrole and furanone rings.

  Journal of agricultural and food chemistry 20020508

• Isopestacin, an isobenzofuranone from Pestalotiopsis microspora, possessing antifungal and antioxidant activities.

  Phytochemistry 20020501

• An approach to furolabdanes and their photooxidation derivatives from R-(+)-sclareolide.

  Journal of natural products 20020501

• First synthesis of the antifungal oidiolactone C from trans-communic acid: cytotoxic and antimicrobial activity in podolactone-related compounds.

  The Journal of organic chemistry 20020419

• The total synthesis of the annonaceous acetogenin, muricatetrocin C.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20020402

• Halogenated furanones inhibit quorum sensing through accelerated LuxR turnover.

  Microbiology (Reading, England) 20020401

• Reactions of purines-containing butenolides with L-cysteine or N-acetyl-L-cysteine as model biological nucleophiles: a potent mechanism-based inhibitor of ribonucleotide reductase caused apoptosis in breast carcinoma MCF7 cells.

  European journal of medicinal chemistry 20020301

• Novel pyrrolo-quinoline derivatives as potent inhibitors for PI3-kinase related kinases.

  Bioorganic & medicinal chemistry 20020101

• Inhibition of quorum sensing in Pseudomonas aeruginosa biofilm bacteria by a halogenated furanone compound.

  Microbiology (Reading, England) 20020101

• Enantioselective carbon-hydrogen insertion is an effective and efficient methodology for the synthesis of (R)-(-)-baclofen.

  Chirality 20020101

• Inhibition of biofilm formation and swarming of Bacillus subtilis by (5Z)-4-bromo-5-(bromomethylene)-3-butyl-2(5H)-furanone.

  Letters in applied microbiology 20020101

• Palladium(0)-catalyzed coupling-cyclization reaction of polymer-supported aryl iodides with 1,2-allenyl carboxylic acids. Solid-phase parallel synthesis of butenolides.

  Journal of combinatorial chemistry 20020101

• Mechanistic studies on the reversible metabolism of rofecoxib to 5-hydroxyrofecoxib in the rat: evidence for transient ring opening of a substituted 2-furanone derivative using stable isotope-labeling techniques.

  Drug metabolism and disposition: the biological fate of chemicals 20011201

• 2-buten-4-olide, an endogenous feeding suppressant, improves spatial performance through brain acidic fibroblast growth factor in mice.

  Brain research bulletin 20011201

• Synthesis of (-)-deoxypukalide, the enantiomer of a degradation product of the furanocembranolide pukalide.

  The Journal of organic chemistry 20011130

• Halogenated furanones from the red alga, Delisea pulchra, inhibit carbapenem antibiotic synthesis and exoenzyme virulence factor production in the phytopathogen Erwinia carotovora.

  FEMS microbiology letters 20011127

• CJ-15,183, a new inhibitor of squalene synthase produced by a fungus, Aspergillus aculeatus.

  The Journal of antibiotics 20011101

• New pyrrolizidinone antibiotics CJ-16,264 and CJ-16,367.

  The Journal of antibiotics 20011101

• Inhibition of biofilm formation and swarming of Escherichia coli by (5Z)-4-bromo-5-(bromomethylene)-3-butyl-2(5H)-furanone.

  Environmental microbiology 20011101

• Design, synthesis, and biological evaluation of novel nucleoside and nucleotide analogues as agents against DNA viruses and/or retroviruses.

  Journal of medicinal chemistry 20011025

• A novel three-component butenolide synthesis.

  Organic letters 20010906

• Identification of a female-specific, antennally active volatile compound of the currant stem girdler.

  Journal of chemical ecology 20010901

• Effects of COX-2 inhibitors on aortic prostacyclin production in cholesterol-fed rabbits.

  Atherosclerosis 20010801

• Enantioselective synthesis of ancepsenolide and its analogs.

  Bioscience, biotechnology, and biochemistry 20010801

• Synthesis and biological evaluation of purine-containing butenolides.

  Journal of medicinal chemistry 20010524

• Approaches to the synthesis of some tyrosine-derived marine sponge metabolites: synthesis of verongamine and purealidin N.

  The Journal of organic chemistry 20010504

• Quinone-annonaceous acetogenins: synthesis and complex I inhibition studies of a new class of natural product hybrids.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20010302

• Two new lactones with mosquito larvicidal activity from three Hortonia species.

  Journal of natural products 20010301

• Enantioselective syntheses of monotetrahydrofuran Annonaceous acetogenins tonkinecin and annonacin starting from carbohydrates.

  The Journal of organic chemistry 20010209

• Molecular structure and vibrational spectra of phenolphthalein and its dianion.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20010201

• Arglabin-DMA, a plant derived sesquiterpene, inhibits farnesyltransferase.

  Oncology reports 20010101

• 2,5-Dimethyl-4-hydroxy-3(2H)-furanone as a secondary metabolite from D-fructose-1,6-diphosphate metabolism by Zygosaccharomyces rouxii.

  Journal of bioscience and bioengineering 20010101