49758-35-2 | L-7-Azatryptophan

Packsize	Purity	Availability	Price	Discounted Price
100mg	98%	in stock	$169.00	$119.00
250mg	97%	in stock	$356.00	$249.00
500mg	97%	in stock	$616.00	$431.00
1g	97%	in stock	$869.00	$608.00
5g	97%	in stock	$2,811.00	$1,968.00

Description

• Catalog Number: AG23097
• Chemical Name: L-7-Azatryptophan
• CAS Number: 49758-35-2
• Molecular Formula: C10H11N3O2
• Molecular Weight: 205.2132
• MDL Number: MFCD08272984
• SMILES: N[C@H](C(=O)O)Cc1c[nH]c2c1cccn2

Computed Properties

• Complexity: 247
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 15
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 3
• XLogP3: -2

Literature

• Biophysical and structural studies of the human calcium- and integrin-binding protein family: understanding their functional similarities and differences.

  Biochemistry and cell biology = Biochimie et biologie cellulaire 20121001

• Monitoring lysin motif-ligand interactions via tryptophan analog fluorescence spectroscopy.

  Analytical biochemistry 20120915

• Native state conformational heterogeneity of HP35 revealed by time-resolved FRET.

  The journal of physical chemistry. B 20120906

• Azatryptophans as tools to study polarity requirements for folding of green fluorescent protein.

  Journal of peptide science : an official publication of the European Peptide Society 20101001

• Non-natural amino acid fluorophores for one- and two-step fluorescence resonance energy transfer applications.

  Analytical biochemistry 20100415

• Blue fluorescent amino acids as in vivo building blocks for proteins.

  Chembiochem : a European journal of chemical biology 20100215

• Single-walled carbon nanotube binding peptides: probing tryptophan's importance by unnatural amino acid substitution.

  The journal of physical chemistry. B 20071227

• Expression of compstatin in Escherichia coli: incorporation of unnatural amino acids enhances its activity.

  Protein expression and purification 20060501

• Catalytic folding of the Cepsilon3 domain by its high affinity receptor.

  FEBS letters 20060403

• Domain-specific incorporation of noninvasive optical probes into recombinant proteins.

  Journal of the American Chemical Society 20041103

• Incorporation of the fluorescent amino acid 7-azatryptophan into the core domain 1-47 of hirudin as a probe of hirudin folding and thrombin recognition.

  Protein science : a publication of the Protein Society 20040601

• Static and time-resolved fluorescence investigations of tryptophan analogues--a solvent study.

  Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20040401

• In vivo properties of thiol inhibitors of the three vasopeptidases NEP, ACE and ECE are improved by introduction of a 7-azatryptophan in P2' position.

  The journal of peptide research : official journal of the American Peptide Society 20040201

• Fluorescence based structural analysis of tryptophan analogue-AMP formation in single tryptophan mutants of Bacillus stearothermophilus tryptophanyl-tRNA synthetase.

  Biochemistry 20031223

• Parallel measurement of Ca2+ binding and fluorescence emission upon Ca2+ titration of recombinant skeletal muscle troponin C. Measurement of sequential calcium binding to the regulatory sites.

  The Journal of biological chemistry 20030328

• Study of protein-protein interactions by fluorescence of tryptophan analogs: application to immunoglobulin G binding domain of streptococcal protein G.

  Biopolymers 20030101

• Interaction of 7-azatryptophan and beta-(1-azulenyl)-alanine with a nitroxyl radical.

  Advances in experimental medicine and biology 20030101

• A concerted structural transition in the plasminogen activator inhibitor-1 mechanism of inhibition.

  Biochemistry 20021008

• Fluorescence resonance energy transfer between unnatural amino acids in a structurally modified dihydrofolate reductase.

  Journal of the American Chemical Society 20020821

• Low temperature luminescence behaviours of 7-azatryptophan, 5-hydroxytryptophan and their chromophoric moieties.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20020701

• Sensitization of lanthanides by nonnatural amino acids.

  Photochemistry and photobiology 20020201

• Protein-protein interaction using tryptophan analogues: novel spectroscopic probes for toxin-elongation factor-2 interactions.

  Biochemistry 20010828

• Crystal structure of the lytic transglycosylase from bacteriophage lambda in complex with hexa-N-acetylchitohexaose.

  Biochemistry 20010515