498-02-2 | 1-(4-hydroxy-3-methoxyphenyl)ethan-1-one

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$8.00	$6.00
5g	98%	in stock	$11.00	$8.00
10g	98%	in stock	$15.00	$11.00
25g	98%	in stock	$18.00	$13.00
100g	98%	in stock	$56.00	$39.00
500g	98%	in stock	$236.00	$165.00

Description

• Catalog Number: AI51138
• Chemical Name: 1-(4-hydroxy-3-methoxyphenyl)ethan-1-one
• CAS Number: 498-02-2
• Molecular Formula: C9H10O3
• Molecular Weight: 166.1739
• MDL Number: MFCD00008747
• SMILES: COc1cc(ccc1O)C(=O)C

Computed Properties

• Complexity: 167
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 12
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 2
• XLogP3: 0.5

Literature

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  International journal of nephrology 20120101

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  Journal of toxicology and environmental health. Part A 20120101

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  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101

• Selective inhibition by apocynin of the proliferation and adhesion to fibronectin of v-H-ras-transformed 3Y1 cells.

  Bioscience, biotechnology, and biochemistry 20120101

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• Protocatechuic acid alkyl esters: hydrophobicity as a determinant factor for inhibition of NADPH oxidase.

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• Wogonin induces reactive oxygen species production and cell apoptosis in human glioma cancer cells.

  International journal of molecular sciences 20120101

• Chronic intermittent hypoxia increases apnoea index in sleeping rats.

  Advances in experimental medicine and biology 20120101

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• Evaluation of correct endogenous reactive oxygen species content for human sperm capacitation and involvement of the NADPH oxidase system.

  Human reproduction (Oxford, England) 20111201

• Angiotensin II-NADPH oxidase-derived superoxide mediates diabetes-attenuated cell excitability of aortic baroreceptor neurons.

  American journal of physiology. Cell physiology 20111201

• Aldosterone increases kidney tubule cell oxidants through calcium-mediated activation of NADPH oxidase and nitric oxide synthase.

  Free radical biology & medicine 20111201

• Apocynin may limit total cell death following cerebral ischemia and reperfusion by enhancing apoptosis.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20111201

• NADPH oxidase inhibition ameliorates Trypanosoma cruzi-induced myocarditis during Chagas disease.

  The Journal of pathology 20111201

• The phosphorylation status of extracellular-regulated kinase 1/2 in astrocytes and neurons from rat hippocampus determines the thrombin-induced calcium release and ROS generation.

  Journal of neurochemistry 20111201

• Apelin-13 passes through the ADMA-damaged endothelial barrier and acts on vascular smooth muscle cells.

  Peptides 20111201

• Suppression of high pacing-induced ANP secretion by antioxidants in isolated rat atria.

  Peptides 20111201

• Chemical constituents of Cynanchum wilfordii and the chemotaxonomy of two species of the family Asclepiadacease, C. wilfordii and C. auriculatum.

  Archives of pharmacal research 20111201

• Pulmonary particulate matter and systemic microvascular dysfunction.

  Research report (Health Effects Institute) 20111201

• Increased oxidative stress, the renin-angiotensin system, and sympathetic overactivation induce hypertension in kidney androgen-regulated protein transgenic mice.

  Free radical biology & medicine 20111115

• Influence of chylomicron remnants on human monocyte activation in vitro.

  Nutrition, metabolism, and cardiovascular diseases : NMCD 20111101

• Increased expression of the transient receptor potential melastatin 7 channel is critically involved in lipopolysaccharide-induced reactive oxygen species-mediated neuronal death.

  Antioxidants & redox signaling 20111101

• Mechanisms regulating superoxide generation in experimental models of phenylketonuria: an essential role of NADPH oxidase.

  Molecular genetics and metabolism 20111101

• β-Adrenergic receptors desensitization is not involved in exercise-induced cardiac fatigue: NADPH oxidase-induced oxidative stress as a new trigger.

  Journal of applied physiology (Bethesda, Md. : 1985) 20111101

• Antenatal nicotine induces heightened oxidative stress and vascular dysfunction in rat offspring.

  British journal of pharmacology 20111101

• Thioredoxin reductase inhibition reduces relaxation by increasing oxidative stress and s-nitrosylation in mouse aorta.

  Journal of cardiovascular pharmacology 20111101

• The central mechanism underlying hypertension: a review of the roles of sodium ions, epithelial sodium channels, the renin-angiotensin-aldosterone system, oxidative stress and endogenous digitalis in the brain.

  Hypertension research : official journal of the Japanese Society of Hypertension 20111101

• Interleukin-10 released by CD4(+)CD25(+) natural regulatory T cells improves microvascular endothelial function through inhibition of NADPH oxidase activity in hypertensive mice.

  Arteriosclerosis, thrombosis, and vascular biology 20111101

• Redox regulation of cytokeratin 18 protein by NADPH oxidase 1 in preneoplastic human epithelial cells.

  Journal of cancer research and clinical oncology 20111101

• Role of VPO1, a newly identified heme-containing peroxidase, in ox-LDL induced endothelial cell apoptosis.

  Free radical biology & medicine 20111015

• Ox-LDL-induced LOX-1 expression in vascular smooth muscle cells: role of reactive oxygen species.

  Fundamental & clinical pharmacology 20111001

• NOX1, 2, 4, 5: counting out oxidative stress.

  British journal of pharmacology 20111001

• Microsomal oxidative damage promoted by acetaminophen metabolism.

  Toxicology in vitro : an international journal published in association with BIBRA 20111001

• Angiotensin II evokes sensory long-term facilitation of the carotid body via NADPH oxidase.

  Journal of applied physiology (Bethesda, Md. : 1985) 20111001

• Profiling of isoflavonoids in Iris germanica rhizome extracts by microprobe NMR and HPLC-PDA-MS analysis.

  Fitoterapia 20111001

• Plasma-assisted pretreatment of wheat straw for ethanol production.

  Applied biochemistry and biotechnology 20111001

• Viscolin reduces VCAM-1 expression in TNF-α-treated endothelial cells via the JNK/NF-κB and ROS pathway.

  Free radical biology & medicine 20111001

• Neutral sphingomyelinase, NADPH oxidase and reactive oxygen species. Role in acute hypoxic pulmonary vasoconstriction.

  Journal of cellular physiology 20111001

• Arsenic-induced alteration in intracellular calcium homeostasis induces head kidney macrophage apoptosis involving the activation of calpain-2 and ERK in Clarias batrachus.

  Toxicology and applied pharmacology 20111001

• Superoxide modulates myogenic contractions of mouse afferent arterioles.

  Hypertension (Dallas, Tex. : 1979) 20111001

• The neuroprotective action of candesartan is related to interference with the early stages of 6-hydroxydopamine-induced dopaminergic cell death.

  The European journal of neuroscience 20111001

• Hyperglycemia promotes tissue plasminogen activator-induced hemorrhage by Increasing superoxide production.

  Annals of neurology 20111001

• Significance of marrow-derived nicotinamide adenine dinucleotide phosphate oxidase in experimental ischemic stroke.

  Annals of neurology 20111001

• NADPH-oxidase-dependent reactive oxygen species mediate EGFR transactivation by FPRL1 in WKYMVm-stimulated human lung cancer cells.

  Free radical biology & medicine 20110915

• Mycobacterial p(1)-type ATPases mediate resistance to zinc poisoning in human macrophages.

  Cell host & microbe 20110915

• Reactive oxygen species-mediated TRPC6 protein activation in vascular myocytes, a mechanism for vasoconstrictor-regulated vascular tone.

  The Journal of biological chemistry 20110909

• Oscillatory shear stress induces mitochondrial superoxide production: implication of NADPH oxidase and c-Jun NH2-terminal kinase signaling.

  Antioxidants & redox signaling 20110901

• Aldosterone stimulates superoxide production in macula densa cells.

  American journal of physiology. Renal physiology 20110901

• Eplerenone suppresses aldosterone/ salt-induced expression of NOX-4.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20110901

• Effect of hypoxia in mice mesenteric arteries surrounded by adipose tissue.

  Acta physiologica (Oxford, England) 20110901

• Different effects of low- and high-dose insulin on ROS production and VEGF expression in bovine retinal microvascular endothelial cells in the presence of high glucose.

  Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20110901

• NADPH oxidases in cardiovascular disease: insights from in vivo models and clinical studies.

  Basic research in cardiology 20110901

• Up-regulation of thromboxane A₂ impairs cerebrovascular eNOS function in aging atherosclerotic mice.

  Pflugers Archiv : European journal of physiology 20110901

• Epithelial-to-mesenchymal transition in podocytes mediated by activation of NADPH oxidase in hyperhomocysteinemia.

  Pflugers Archiv : European journal of physiology 20110901

• Effects of acute and chronic endurance exercise on intracellular nitric oxide and superoxide in circulating CD34⁺ and CD34⁻ cells.

  Journal of applied physiology (Bethesda, Md. : 1985) 20110901

• Compound C stimulates heme oxygenase-1 gene expression via the Nrf2-ARE pathway to preserve human endothelial cell survival.

  Biochemical pharmacology 20110815

• Conformational behaviour, hydrogen bond competition and intramolecular dynamics in vanillin derivatives: acetovanillone and 6-hydroxy-3-methoxyacetophenone.

  Physical chemistry chemical physics : PCCP 20110807

• Regulation of cyclooxygenase-2 and cytosolic phospholipase A2 gene expression by lipopolysaccharide through the RNA-binding protein HuR: involvement of NADPH oxidase, reactive oxygen species and mitogen-activated protein kinases.

  British journal of pharmacology 20110801

• The endothelium-derived contracting factor uridine adenosine tetraphosphate induces P2Y(2)-mediated pro-inflammatory signaling by monocyte chemoattractant protein-1 formation.

  Journal of molecular medicine (Berlin, Germany) 20110801

• Silver nanoparticles exert a long-lasting antiproliferative effect on human keratinocyte HaCaT cell line.

  Toxicology in vitro : an international journal published in association with BIBRA 20110801

• Activation and induction of cytosolic phospholipase A2 by TNF-α mediated through Nox2, MAPKs, NF-κB, and p300 in human tracheal smooth muscle cells.

  Journal of cellular physiology 20110801

• Nox2-derived reactive oxygen species contribute to hypercholesterolemia-induced inhibition of neovascularization: effects on endothelial progenitor cells and mature endothelial cells.

  Atherosclerosis 20110801

• Endothelial microparticle formation by angiotensin II is mediated via Ang II receptor type I/NADPH oxidase/ Rho kinase pathways targeted to lipid rafts.

  Arteriosclerosis, thrombosis, and vascular biology 20110801

• NADPH oxidase pathway is involved in aortic contraction induced by A3 adenosine receptor in mice.

  The Journal of pharmacology and experimental therapeutics 20110801

• Apocynin attenuates ventilator-induced lung injury in an isolated and perfused rat lung model.

  Intensive care medicine 20110801

• Nox2-derived ROS in PPARγ signaling and cell-cycle progression of lung alveolar epithelial cells.

  Free radical biology & medicine 20110801

• Heme oxygenase 1 is differentially involved in blood flow-dependent arterial remodeling: role of inflammation, oxidative stress, and nitric oxide.

  Hypertension (Dallas, Tex. : 1979) 20110801

• NADPH oxidase and eNOS control cardiomyogenesis in mouse embryonic stem cells on ascorbic acid treatment.

  Free radical biology & medicine 20110715

• Vascular generation of tumor necrosis factor-α reduces nitric oxide availability in small arteries from visceral fat of obese patients.

  Journal of the American College of Cardiology 20110712

• Fibrotic response induced by angiotensin-II requires NAD(P)H oxidase-induced reactive oxygen species (ROS) in skeletal muscle cells.

  Biochemical and biophysical research communications 20110708

• Involvement of vascular peroxidase 1 in angiotensin II-induced vascular smooth muscle cell proliferation.

  Cardiovascular research 20110701

• Relative contributions of mitochondria and NADPH oxidase to deoxycorticosterone acetate-salt hypertension in mice.

  Kidney international 20110701

• Reactive oxygen species (ROS) from NADPH and xanthine oxidase modulate the cutaneous local heating response in healthy humans.

  Journal of applied physiology (Bethesda, Md. : 1985) 20110701

• Catalase and superoxide dismutase conjugated with platelet-endothelial cell adhesion molecule antibody distinctly alleviate abnormal endothelial permeability caused by exogenous reactive oxygen species and vascular endothelial growth factor.

  The Journal of pharmacology and experimental therapeutics 20110701

• Synthesis and biological evaluations of novel apocynin analogues.

  European journal of medicinal chemistry 20110701

• Type 1 diabetes-induced hyper-responsiveness to 5-hydroxytryptamine in rat pulmonary arteries via oxidative stress and induction of cyclooxygenase-2.

  The Journal of pharmacology and experimental therapeutics 20110701

• Precision studies in supramolecular chemistry: a 1H NMR study of hydroxymethoxyacetophenone/β-cyclodextrin complexes.

  Magnetic resonance in chemistry : MRC 20110701

• Nox4 regulates Nrf2 and glutathione redox in cardiomyocytes in vivo.

  Free radical biology & medicine 20110701

• Albumin overload activates intrarenal renin-angiotensin system through protein kinase C and NADPH oxidase-dependent pathway.

  Journal of hypertension 20110701

• Cigarette smoke-induced kinin B1 receptor promotes NADPH oxidase activity in cultured human alveolar epithelial cells.

  Peptides 20110701

• Effect of NADPH-oxidase inhibitors in the experimental model of zymosan-induced shock in mice.

  Free radical research 20110701

• Blockade of NADPH oxidase restores vasoreparative function in diabetic CD34+ cells.

  Investigative ophthalmology & visual science 20110701

• Apocynin attenuates ischemia-reperfusion lung injury in an isolated and perfused rat lung model.

  Translational research : the journal of laboratory and clinical medicine 20110701

• 4-fluoro-2-methoxyphenol, an apocynin analog with enhanced inhibitory effect on leukocyte oxidant production and phagocytosis.

  European journal of pharmacology 20110625

• Interrupted reperfusion reduces the activation of NADPH oxidase after cerebral I/R injury.

  Free radical biology & medicine 20110615

• Angiotensin II induced catabolic effect and muscle atrophy are redox dependent.

  Biochemical and biophysical research communications 20110603

• Cellular stress from excitatory neurotransmission contributes to cholesterol loss in hippocampal neurons aging in vitro.

  Neurobiology of aging 20110601

• Oxidative stress in obstructive nephropathy.

  International journal of experimental pathology 20110601

• Nitrite supplementation reverses vascular endothelial dysfunction and large elastic artery stiffness with aging.

  Aging cell 20110601

• Differential effects of NADPH oxidase and xanthine oxidase inhibition on sympathetic reinnervation in postinfarct rat hearts.

  Free radical biology & medicine 20110601

• Balloon catheter injury abolishes phenylephrine-induced relaxation in the rat contralateral carotid.

  British journal of pharmacology 20110601

• Novel role of AMP-activated protein kinase signaling in cigarette smoke induction of IL-8 in human lung epithelial cells and lung inflammation in mice.

  Free radical biology & medicine 20110601

• Effect of NADPH oxidase inhibition on the expression of kidney injury molecule and calcium oxalate crystal deposition in hydroxy-L-proline-induced hyperoxaluria in the male Sprague-Dawley rats.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20110601

• Kaempferol attenuates 4-hydroxynonenal-induced apoptosis in PC12 cells by directly inhibiting NADPH oxidase.

  The Journal of pharmacology and experimental therapeutics 20110601

• Inward remodeling of resistance arteries requires reactive oxygen species-dependent activation of matrix metalloproteinases.

  American journal of physiology. Heart and circulatory physiology 20110601

• Endogenous hydrogen peroxide up-regulates the expression of nitric oxide synthase in the kidney of SHR.

  Journal of hypertension 20110601

• Effect of angiotensin II and its receptor antagonists on human corpus cavernous contractility and oxidative stress: modulation of nitric oxide mediated relaxation.

  The Journal of urology 20110601

• NADPH treatment decreases C6 glioma cell survival by increasing oxidative stress.

  Frontiers in bioscience (Elite edition) 20110601

• Tetrahydrobiopterin attenuates superoxide-induced reduction in nitric oxide.

  Frontiers in bioscience (Scholar edition) 20110601

• Reversal by growth hormone of homocysteine-induced epithelial-to-mesenchymal transition through membrane raft-redox signaling in podocytes.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20110601

• Dehydroepiandrosterone protects against oxidative stress-induced endothelial dysfunction in ovariectomized rats.

  The Journal of physiology 20110515

• NADPH oxidase 1 mediates upregulation of thromboxane A2 synthase in human vascular smooth muscle cells: inhibition with iloprost.

  European journal of pharmacology 20110511

• NAD(P)H oxidase-derived reactive oxygen species contribute to age-related impairments of endothelium-dependent dilation in rat soleus feed arteries.

  Journal of applied physiology (Bethesda, Md. : 1985) 20110501

• Inhibition of NADPH oxidase alleviates experimental diabetes-induced myocardial contractile dysfunction.

  Diabetes, obesity & metabolism 20110501

• Mammalian Ste20-like protein kinase 3 plays a role in hypoxia-induced apoptosis of trophoblast cell line 3A-sub-E.

  The international journal of biochemistry & cell biology 20110501

• Role of reactive oxygen species in the regulation of cardiac contractility.

  Journal of molecular and cellular cardiology 20110501

• Oxidative stress impairs insulin signal in skeletal muscle and causes insulin resistance in postinfarct heart failure.

  American journal of physiology. Heart and circulatory physiology 20110501

• CRP enhances soluble LOX-1 release from macrophages by activating TNF-α converting enzyme.

  Journal of lipid research 20110501

• Endogenous production of reactive oxygen species by the NADPH oxidase complexes is a determinant of γ-glutamyltransferase expression.

  Free radical research 20110501

• Effects of laccase-natural mediator systems on kenaf pulp.

  Bioresource technology 20110501

• The role of NADPH oxidase in multi-walled carbon nanotubes-induced oxidative stress and cytotoxicity in human macrophages.

  Journal of nanoscience and nanotechnology 20110501

• Murine prolylcarboxypeptidase depletion induces vascular dysfunction with hypertension and faster arterial thrombosis.

  Blood 20110407

• Apocynin administration does not improve behavioral and neuropathological deficits in a transgenic mouse model of Alzheimer's disease.

  Neuroscience letters 20110404

• Induction of HO-1 and redox signaling in endothelial cells by advanced glycation end products: a role for Nrf2 in vascular protection in diabetes.

  Nutrition, metabolism, and cardiovascular diseases : NMCD 20110401

• Red wine polyphenols prevent endothelial dysfunction induced by endothelin-1 in rat aorta: role of NADPH oxidase.

  Clinical science (London, England : 1979) 20110401

• Redox-sensitive regulation of macrophage-inducible nitric oxide synthase expression in vitro does not correlate with the failure of apocynin to prevent lung inflammation induced by endotoxin.

  Immunobiology 20110401

• Hyperuricemia as a mediator of the proinflammatory endocrine imbalance in the adipose tissue in a murine model of the metabolic syndrome.

  Diabetes 20110401

• GroEL1, a heat shock protein 60 of Chlamydia pneumoniae, induces lectin-like oxidized low-density lipoprotein receptor 1 expression in endothelial cells and enhances atherogenesis in hypercholesterolemic rabbits.

  Journal of immunology (Baltimore, Md. : 1950) 20110401

• Multiple multi-copper oxidase gene families in basidiomycetes - what for?

  Current genomics 20110401

• Serotonin 2A and 2B receptor-induced phrenic motor facilitation: differential requirement for spinal NADPH oxidase activity.

  Neuroscience 20110331

• Enhancement of reactive oxygen species and induction of apoptosis in streptozotocin-induced diabetic rats under hyperbaric oxygen exposure.

  International journal of clinical and experimental pathology 20110331

• Involvement of H-Ras and reactive oxygen species in proinflammatory cytokine-induced matrix metalloproteinase-13 expression in human articular chondrocytes.

  Archives of biochemistry and biophysics 20110315

• NADPH oxidase mediates striatal neuronal injury after transient global cerebral ischemia.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20110301

• Evidence that α-lipoic acid inhibits NF-κB activation independent of its antioxidant function.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20110301

• Myocardial oxidative stress contributes to transgenic β₂-adrenoceptor activation-induced cardiomyopathy and heart failure.

  British journal of pharmacology 20110301

• Phenolic compounds as enhancers in enzymatic and electrochemical oxidation of veratryl alcohol and lignins.

  Applied microbiology and biotechnology 20110301

• Inhibition of mineralocorticoid receptor is a renoprotective effect of the 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor pitavastatin.

  Journal of hypertension 20110301

• Tachycardia of atrial myocytes induces collagen expression in atrial fibroblasts through transforming growth factor β1.

  Cardiovascular research 20110301

• Effect of apocynin, a NADPH oxidase inhibitor, on acute lung inflammation.

  Biochemical pharmacology 20110301

• Superoxide anions in the paraventricular nucleus mediate the enhanced cardiac sympathetic afferent reflex and sympathetic activity in renovascular hypertensive rats.

  Journal of applied physiology (Bethesda, Md. : 1985) 20110301

• α1AMP-activated protein kinase preserves endothelial function during chronic angiotensin II treatment by limiting Nox2 upregulation.

  Arteriosclerosis, thrombosis, and vascular biology 20110301

• Phagocyte-like NADPH oxidase generates ROS in INS 832/13 cells and rat islets: role of protein prenylation.

  American journal of physiology. Regulatory, integrative and comparative physiology 20110301

• Role for peroxynitrite in sphingosine-1-phosphate-induced hyperalgesia in rats.

  Pain 20110301

• Mitochondrial complex I and NAD(P)H oxidase are major sources of exacerbated oxidative stress in pressure-overloaded ischemic-reperfused hearts.

  Basic research in cardiology 20110301

• NADPH oxidase-mediated oxidative damage to proteins in the postsynaptic density after transient cerebral ischemia and reperfusion.

  Molecular and cellular neurosciences 20110301

• Intracavernous delivery of a designed angiopoietin-1 variant rescues erectile function by enhancing endothelial regeneration in the streptozotocin-induced diabetic mouse.

  Diabetes 20110301

• Acute NADPH oxidase activation potentiates cerebrovascular permeability response to bradykinin in ischemia-reperfusion.

  Free radical biology & medicine 20110215

• Modulation of NADPH oxidase activation in cerebral ischemia/reperfusion injury in rats.

  Brain research 20110204

• Effect of Apocynin, an inhibitor of NADPH oxidase, in the inflammatory process induced by an experimental model of spinal cord injury.

  Free radical research 20110201

• Superoxide induced by a high-glucose concentration attenuates production of angiogenic growth factors in hypoxic mouse mesenchymal stem cells.

  The Journal of endocrinology 20110201

• Central interactions of aldosterone and angiotensin II in aldosterone- and angiotensin II-induced hypertension.

  American journal of physiology. Heart and circulatory physiology 20110201

• Reactive oxygen species cause endothelial dysfunction in chronic flow overload.

  Journal of applied physiology (Bethesda, Md. : 1985) 20110201

• NADPH oxidase-derived reactive oxygen species mediate decidualization of human endometrial stromal cells in response to cyclic AMP signaling.

  Endocrinology 20110201

• Cigarette smoke extract regulates cytosolic phospholipase A2 expression via NADPH oxidase/MAPKs/AP-1 and p300 in human tracheal smooth muscle cells.

  Journal of cellular biochemistry 20110201

• Inhibition of Nox2 oxidase activity ameliorates influenza A virus-induced lung inflammation.

  PLoS pathogens 20110201

• ASIC-like currents in freshly isolated cerebral artery smooth muscle cells are inhibited by endogenous oxidase activity.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20110201

• Acute superoxide scavenging restores depressed baroreflex sensitivity in renovascular hypertensive rats.

  Autonomic neuroscience : basic & clinical 20110120

• Lipopolysaccharide-induced cytokine expression in alveolar epithelial cells: role of PKCζ-mediated p47phox phosphorylation.

  Chemico-biological interactions 20110115

• Inhibition of renal gluconeogenesis contributes to hypoglycaemic action of NADPH oxidase inhibitor, apocynin.

  Chemico-biological interactions 20110115

• Mitochondrial superoxide anion radicals mediate induction of apoptosis in cardiac myoblasts exposed to chronic hypoxia.

  Archives of biochemistry and biophysics 20110115

• Chronic intake of red wine polyphenols by young rats prevents aging-induced endothelial dysfunction and decline in physical performance: role of NADPH oxidase.

  Biochemical and biophysical research communications 20110114

• Neuromelanin activates microglia and induces degeneration of dopaminergic neurons: implications for progression of Parkinson's disease.

  Neurotoxicity research 20110101

• Selective ascorbate toxicity in malignant mesothelioma: a redox Trojan mechanism.

  American journal of respiratory cell and molecular biology 20110101

• Pro-inflammatory effects of interleukin-17A on vascular smooth muscle cells involve NAD(P)H- oxidase derived reactive oxygen species.

  Journal of vascular research 20110101

• Indoxyl sulfate-induced endothelial dysfunction in patients with chronic kidney disease via an induction of oxidative stress.

  Clinical journal of the American Society of Nephrology : CJASN 20110101

• Cellular iron depletion weakens induction of heme oxygenase-1 by cadmium.

  The international journal of biochemistry & cell biology 20110101

• Phagocyte-like NADPH oxidase promotes cytokine-induced mitochondrial dysfunction in pancreatic β-cells: evidence for regulation by Rac1.

  American journal of physiology. Regulatory, integrative and comparative physiology 20110101

• Folic acid supplementation inhibits NADPH oxidase-mediated superoxide anion production in the kidney.

  American journal of physiology. Renal physiology 20110101

• Angiotensin II induces afterdepolarizations via reactive oxygen species and calmodulin kinase II signaling.

  Journal of molecular and cellular cardiology 20110101

• Amorphous nanosilica induce endocytosis-dependent ROS generation and DNA damage in human keratinocytes.

  Particle and fibre toxicology 20110101

• Occupational exposure to phenolic compounds at coke plants--urinary excretion of methoxyphenols as an indicator of exposure to methoxyphenols.

  Journal of occupational health 20110101

• Ncf1 (p47phox) is essential for direct regulatory T cell mediated suppression of CD4+ effector T cells.

  PloS one 20110101

• Vascular dysfunction in streptozotocin-induced experimental diabetes strictly depends on insulin deficiency.

  Journal of vascular research 20110101

• Cocoa flavanols: effects on vascular nitric oxide and blood pressure.

  Journal of clinical biochemistry and nutrition 20110101

• Oxidative stress in cardiac and skeletal muscle dysfunction associated with diabetes mellitus.

  Journal of clinical biochemistry and nutrition 20110101

• Endotoxin-activated microglia injure brain derived endothelial cells via NF-κB, JAK-STAT and JNK stress kinase pathways.

  Journal of inflammation (London, England) 20110101

• Clinical review: ventilator-induced diaphragmatic dysfunction--human studies confirm animal model findings!

  Critical care (London, England) 20110101

• Inhibition of renin-angiotensin system reverses endothelial dysfunction and oxidative stress in estrogen deficient rats.

  PloS one 20110101

• A growth factor attenuates HIV-1 Tat and morphine induced damage to human neurons: implication in HIV/AIDS-drug abuse cases.

  PloS one 20110101

• 1-[3-Meth-oxy-4-(prop-2-yn-1-yl-oxy)phen-yl]ethanone.

  Acta crystallographica. Section E, Structure reports online 20110101

• Role of endothelial Nox2 NADPH oxidase in angiotensin II-induced hypertension and vasomotor dysfunction.

  Basic research in cardiology 20110101

• Non-endothelial endothelin counteracts hypoxic vasodilation in porcine large coronary arteries.

  BMC physiology 20110101

• Impairment by hypoxia or hypoxia/reoxygenation of nitric oxide-mediated relaxation in isolated monkey coronary artery: the role of intracellular superoxide.

  Journal of pharmacological sciences 20110101

• Intermittent hypoxia-induced cognitive deficits are mediated by NADPH oxidase activity in a murine model of sleep apnea.

  PloS one 20110101

• Anti-inflammatory activity of Chios mastic gum is associated with inhibition of TNF-alpha induced oxidative stress.

  Nutrition journal 20110101

• Chronic apocynin treatment attenuates beta amyloid plaque size and microglial number in hAPP(751)(SL) mice.

  PloS one 20110101

• Functional characterization of human Cd33+ and Cd11b+ myeloid-derived suppressor cell subsets induced from peripheral blood mononuclear cells co-cultured with a diverse set of human tumor cell lines.

  Journal of translational medicine 20110101

• 3',4'-Dihydroxyflavonol reduces superoxide and improves nitric oxide function in diabetic rat mesenteric arteries.

  PloS one 20110101

• Apocynin stimulates osteoblast differentiation and inhibits bone-resorbing mediators in MC3T3-E1 cells.

  Cellular immunology 20110101

• NOX2, p22phox and p47phox are targeted to the nuclear pore complex in ischemic cardiomyocytes colocalizing with local reactive oxygen species.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20110101

• Neonatal astrocyte damage is sufficient to trigger progressive striatal degeneration in a rat model of glutaric acidemia-I.

  PloS one 20110101

• Modification by antioxidant supplementation of changes in human lung function associated with air pollutant exposure: a systematic review.

  BMC public health 20110101

• Anti-inflammatory effects of Chinese medicinal herbs on cerebral ischemia.

  Chinese medicine 20110101

• Oxidative Stress and Vascular Damage in Hypertension: Role of Angiotensin II.

  International journal of hypertension 20110101

• Design and development of a stable polyherbal formulation based on the results of compatibility studies.

  Pharmacognosy research 20110101

• Particulate matter exposure exacerbates high glucose-induced cardiomyocyte dysfunction through ROS generation.

  PloS one 20110101

• Cigarette smoke extract upregulates heme oxygenase-1 via PKC/NADPH oxidase/ROS/PDGFR/PI3K/Akt pathway in mouse brain endothelial cells.

  Journal of neuroinflammation 20110101

• Decolorization of Solophenyl Red 3BL Polyazo Dye by Laccase-Mediator System: Optimization through Response Surface Methodology.

  Enzyme research 20110101

• Increased oxidative stress induces apoptosis in human cystic fibrosis cells.

  PloS one 20110101

• Reactive oxygen species drive herpes simplex virus (HSV)-1-induced proinflammatory cytokine production by murine microglia.

  Journal of neuroinflammation 20110101

• Hypertension and other morbidities with Cushing's syndrome associated with corticosteroids: a review.

  Integrated blood pressure control 20110101

• Aging negatively affects estrogens-mediated effects on nitric oxide bioavailability by shifting ERα/ERβ balance in female mice.

  PloS one 20110101

• Generation of reactive oxygen species in 1-methyl-4-phenylpyridinium (MPP+) treated dopaminergic neurons occurs as an NADPH oxidase-dependent two-wave cascade.

  Journal of neuroinflammation 20110101

• Delayed inflammatory mRNA and protein expression after spinal cord injury.

  Journal of neuroinflammation 20110101

• Mechanisms for vascular cell adhesion molecule-1 activation of ERK1/2 during leukocyte transendothelial migration.

  PloS one 20110101

• Manganese superoxide dismutase: guardian of the powerhouse.

  International journal of molecular sciences 20110101

• Visfatin impairs endothelium-dependent relaxation in rat and human mesenteric microvessels through nicotinamide phosphoribosyltransferase activity.

  PloS one 20110101

• Anti-oxidative effect of apocynin on insulin resistance in high-fat diet mice.

  Annals of clinical and laboratory science 20110101

• Endothelial dysfunction in the apolipoprotein E-deficient mouse: insights into the influence of diet, gender and aging.

  Lipids in health and disease 20110101

• Nicorandil prevents endothelial dysfunction due to antioxidative effects via normalisation of NADPH oxidase and nitric oxide synthase in streptozotocin diabetic rats.

  Cardiovascular diabetology 20110101

• The role of uridine adenosine tetraphosphate in the vascular system.

  Advances in pharmacological sciences 20110101

• Neural degeneration in the retina of the streptozotocin-induced type 1 diabetes model.

  Experimental diabetes research 20110101

• Nox2 oxidase activity accounts for the oxidative stress and vasomotor dysfunction in mouse cerebral arteries following ischemic stroke.

  PloS one 20110101

• What is new in the liver sinusoids? meeting report, 16th International Symposium on Cells of the Hepatic Sinusoid (ISCHS).

  Fibrogenesis & tissue repair 20110101

• Date fruit extract is a neuroprotective agent in diabetic peripheral neuropathy in streptozotocin-induced diabetic rats: a multimodal analysis.

  Oxidative medicine and cellular longevity 20110101

• New role for L-arginine in regulation of inducible nitric-oxide-synthase-derived superoxide anion production in raw 264.7 macrophages.

  TheScientificWorldJournal 20110101

• Defense Mechanisms of Hepatocytes Against Burkholderia pseudomallei.

  Frontiers in microbiology 20110101

• Reactive oxygen species mediate lysophosphatidic acid induced signaling in ovarian cancer cells.

  Free radical biology & medicine 20101215

• Indoxyl sulfate induces leukocyte-endothelial interactions through up-regulation of E-selectin.

  The Journal of biological chemistry 20101210

• 8-isoprostane F2α up-regulates the expression of type 5 phosphodiesterase in cavernosal vascular smooth muscle cells: inhibition with sildenafil, iloprost, nitric oxide and picotamide.

  BJU international 20101201

• p22phox-dependent NADPH oxidase activity is required for megakaryocytic differentiation.

  Cell death and differentiation 20101201

• Angiotensin II upregulates Ca(V)1.2 protein expression in cultured arteries via endothelial H(2)O(2) production.

  Journal of vascular research 20101201

• Japanese encephalitis virus induces matrix metalloproteinase-9 in rat brain astrocytes via NF-κB signalling dependent on MAPKs and reactive oxygen species.

  British journal of pharmacology 20101201

• AT₁ receptor and NAD(P)H oxidase mediate angiotensin II-stimulated antioxidant enzymes and mitogen-activated protein kinase activity in the rat hypothalamus.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20101201

• Effect of inhibitors of NADPH oxidase complex and mitochondrial ATP-sensitive potassium channels on generation of dopaminergic neurons from neurospheres of mesencephalic precursors.

  Developmental dynamics : an official publication of the American Association of Anatomists 20101201

• Homocysteine enhances cell proliferation in vascular smooth muscle cells: role of p38 MAPK and p47phox.

  Acta biochimica et biophysica Sinica 20101201

• Arecoline, a major alkaloid of the areca nut, causes neurotoxicity through enhancement of oxidative stress and suppression of the antioxidant protective system.

  Free radical biology & medicine 20101130

• Role of oxidative stress in high-glucose- and diabetes-induced increased expression of Gq/11α proteins and associated signaling in vascular smooth muscle cells.

  Free radical biology & medicine 20101115

• Reactive oxygen species and the structural remodeling of the visual system after ocular enucleation.

  Neuroscience 20101110

• Reactive oxygen species generated by NADPH oxidase are involved in neurodegeneration in the pilocarpine model of temporal lobe epilepsy.

  Neuroscience letters 20101105

• Receptor for AGEs (RAGE) blockade may exert its renoprotective effects in patients with diabetic nephropathy via induction of the angiotensin II type 2 (AT2) receptor.

  Diabetologia 20101101

• Alcohol-induced exacerbation of ischemic brain injury: role of NAD(P)H oxidase.

  Alcoholism, clinical and experimental research 20101101

• Hypochlorite-oxidized LDL induces intraplatelet ROS formation and surface exposure of CD40L--a prominent role of CD36.

  Atherosclerosis 20101101

• Intrinsic nitric oxide and superoxide production regulates descending vasa recta contraction.

  American journal of physiology. Renal physiology 20101101

• HIV protease inhibitors elicit volume-sensitive Cl- current in cardiac myocytes via mitochondrial ROS.

  Journal of molecular and cellular cardiology 20101101

• Protective effects of apocynin, an inhibitor of NADPH oxidase activity, in splanchnic artery occlusion and reperfusion.

  Journal of leukocyte biology 20101101

• Impaired flow-induced dilation of coronary arterioles of dogs fed a low-salt diet: roles of ANG II, PKC, and NAD(P)H oxidase.

  American journal of physiology. Heart and circulatory physiology 20101101

• Rac1-dependent intracellular superoxide formation mediates vascular endothelial growth factor-induced placental angiogenesis in vitro.

  Endocrinology 20101101

• Renal function and vasomotor activity in mice lacking the Cyp4a14 gene.

  Experimental biology and medicine (Maywood, N.J.) 20101101

• Reactive oxygen species-activated p38/ERK 1/2 MAPK signaling pathway in the Mycobacterium bovis bacillus Calmette Guérin (BCG)-induced CCL2 secretion in human monocytic cell line THP-1.

  Archives of medical research 20101101

• The DOCA-Salt Hypertensive Rat as a Model of Cardiovascular Oxidative and Inflammatory Stress.

  Current cardiology reviews 20101101

• Transcriptional upregulation of brain-derived neurotrophic factor in rostral ventrolateral medulla by angiotensin II: significance in superoxide homeostasis and neural regulation of arterial pressure.

  Circulation research 20101029

• Bone morphogenic protein-4 impairs endothelial function through oxidative stress-dependent cyclooxygenase-2 upregulation: implications on hypertension.

  Circulation research 20101015

• Spinal NADPH oxidase is a source of superoxide in the development of morphine-induced hyperalgesia and antinociceptive tolerance.

  Neuroscience letters 20101011

• NADPH oxidase-derived superoxide impairs calcium transients and contraction in aged murine ventricular myocytes.

  Experimental gerontology 20101001

• NADPH oxidase inhibition ameliorates cardiac dysfunction in rabbits with heart failure.

  Molecular and cellular biochemistry 20101001

• NOX2 deficiency protects against streptozotocin-induced beta-cell destruction and development of diabetes in mice.

  Diabetes 20101001

• Inhibition of NAD(P)H oxidase potentiates AT2 receptor agonist-induced natriuresis in Sprague-Dawley rats.

  American journal of physiology. Renal physiology 20101001

• Contributory role of endothelium and voltage-gated potassium channels in apocynin-induced vasorelaxations.

  Journal of hypertension 20101001

• Impaired 3',5'-cyclic adenosine monophosphate-mediated signaling in immediate early responsive gene X-1-deficient vascular smooth muscle cells.

  Hypertension (Dallas, Tex. : 1979) 20101001

• Role of reactive oxygen species in hyperadrenergic hypertension: biochemical, physiological, and pharmacological evidence from targeted ablation of the chromogranin a (Chga) gene.

  Circulation. Cardiovascular genetics 20101001

• The role of vascular endothelial growth factor-induced activation of NADPH oxidase in choroidal endothelial cells and choroidal neovascularization.

  The American journal of pathology 20101001

• The anti-platelet effects of apocynin in mice are not mediated by inhibition of NADPH oxidase activity.

  Naunyn-Schmiedeberg's archives of pharmacology 20101001

• Indoxyl sulfate stimulates monocyte chemoattractant protein-1 expression in human umbilical vein endothelial cells by inducing oxidative stress through activation of the NADPH oxidase-nuclear factor-κB pathway.

  Circulation journal : official journal of the Japanese Circulation Society 20101001

• Comparative pharmacology of chemically distinct NADPH oxidase inhibitors.

  British journal of pharmacology 20101001

• [Reactive oxygen species participates in low glucose-induced injury of ECV304 cells].

  Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20101001

• Angiotensin II type 1 receptor-dependent oxidative stress mediates endothelial dysfunction in type 2 diabetic mice.

  Antioxidants & redox signaling 20100915

• Increased responsiveness to JNK1/2 mediates the enhanced H2O2-induced stimulation of Cl-/HCO3- exchanger activity in immortalized renal proximal tubular epithelial cells from the SHR.

  Biochemical pharmacology 20100915

• ICAM-1 cytoplasmic tail regulates endothelial glutathione synthesis through a NOX4/PI3-kinase-dependent pathway.

  Free radical biology & medicine 20100915

• Reactive oxygen species and small-conductance calcium-dependent potassium channels are key mediators of inflammation-induced hypotension and shock.

  Journal of molecular medicine (Berlin, Germany) 20100901

• Reduction of endothelial tight junction proteins is related to cerebral aneurysm formation in rats.

  Journal of hypertension 20100901

• Hypoxic relaxation of penile arteries: involvement of endothelial nitric oxide and modulation by reactive oxygen species.

  American journal of physiology. Heart and circulatory physiology 20100901

• High-salt intake enhances superoxide activity in eNOS knockout mice leading to the development of salt sensitivity.

  American journal of physiology. Renal physiology 20100901

• Hypercholesterolemia-induced erectile dysfunction: endothelial nitric oxide synthase (eNOS) uncoupling in the mouse penis by NAD(P)H oxidase.

  The journal of sexual medicine 20100901

• Differential effects of formaldehyde exposure on the cell influx and vascular permeability in a rat model of allergic lung inflammation.

  Toxicology letters 20100901

• Evidence for the role of oxidative stress in the acetylation of histone H3 by ethanol in rat hepatocytes.

  Alcohol (Fayetteville, N.Y.) 20100901

• Post-stroke inhibition of induced NADPH oxidase type 4 prevents oxidative stress and neurodegeneration.

  PLoS biology 20100901

• Elevated systemic TGF-beta impairs aortic vasomotor function through activation of NADPH oxidase-driven superoxide production and leads to hypertension, myocardial remodeling, and increased plaque formation in apoE(-/-) mice.

  American journal of physiology. Heart and circulatory physiology 20100801

• Uremia induces abnormal oxygen consumption in tubules and aggravates chronic hypoxia of the kidney via oxidative stress.

  American journal of physiology. Renal physiology 20100801

• Deficiency of rac1 blocks NADPH oxidase activation, inhibits endoplasmic reticulum stress, and reduces myocardial remodeling in a mouse model of type 1 diabetes.

  Diabetes 20100801

• Involvement of angiotensin II in the remodeling induced by a chronic decrease in blood flow in rat mesenteric resistance arteries.

  Hypertension research : official journal of the Japanese Society of Hypertension 20100801

• Pitavastatin and 4'-hydroxy-3'-methoxyacetophenone (HMAP) reduce cognitive dysfunction in vascular dementia during experimental diabetes.

  Current neurovascular research 20100801

• Role of H(2)O(2) on the kinetics of low-affinity high-capacity Na(+)-dependent alanine transport in SHR proximal tubular epithelial cells.

  Biochemical and biophysical research communications 20100730

• Angiotensin-(1-7) prevents diabetes-induced attenuation in PPAR-gamma and catalase activities.

  European journal of pharmacology 20100725

• NADPH oxidase is involved in protein kinase CKII down-regulation-mediated senescence through elevation of the level of reactive oxygen species in human colon cancer cells.

  FEBS letters 20100716

• Angiotensin II stimulates thick ascending limb superoxide production via protein kinase C(α)-dependent NADPH oxidase activation.

  The Journal of biological chemistry 20100709

• Granzyme B of cytotoxic T cells induces extramitochondrial reactive oxygen species production via caspase-dependent NADPH oxidase activation.

  Immunology and cell biology 20100701

• Polychlorinated biphenyls disrupt intestinal integrity via NADPH oxidase-induced alterations of tight junction protein expression.

  Environmental health perspectives 20100701

• An integrated imaging approach to the study of oxidative stress generation by mitochondrial dysfunction in living cells.

  Environmental health perspectives 20100701

• Impact of elevated dietary sodium intake on NAD(P)H oxidase and SOD in the cortex and medulla of the rat kidney.

  American journal of physiology. Regulatory, integrative and comparative physiology 20100701

• Periadventitial adipose tissue promotes endothelial dysfunction via oxidative stress in diet-induced obese C57Bl/6 mice.

  Circulation journal : official journal of the Japanese Circulation Society 20100701

• The roles of NADPH-oxidase and nNOS for the increased oxidative stress and the oxygen consumption in the diabetic kidney.

  Diabetes/metabolism research and reviews 20100701

• Apocynin attenuates pressure overload-induced cardiac hypertrophy in rats by reducing levels of reactive oxygen species.

  Canadian journal of physiology and pharmacology 20100701

• [Phenol constituents of Pachysandra terminalis and their antioxidant activity].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100701

• Antioxidant treatment restores prejunctional regulation of purinergic transmission in mesenteric arteries of deoxycorticosterone acetate-salt hypertensive rats.

  Neuroscience 20100630

• Pro-oxidant activity of apocynin radical.

  Free radical biology & medicine 20100615

• Molecular mechanisms involving sigma receptor-mediated induction of MCP-1: implication for increased monocyte transmigration.

  Blood 20100610

• Inflammation and apoptosis in aortic tissues of aged type II diabetes: amelioration with alpha-lipoic acid through phosphatidylinositol 3-kinase/Akt- dependent mechanism.

  Life sciences 20100605

• AT1 blockade attenuates atherosclerotic plaque destabilization accompanied by the suppression of cathepsin S activity in apoE-deficient mice.

  Atherosclerosis 20100601

• Short-term calorie restriction reverses vascular endothelial dysfunction in old mice by increasing nitric oxide and reducing oxidative stress.

  Aging cell 20100601

• Activation of AMP-activated protein kinase inhibits oxidized LDL-triggered endoplasmic reticulum stress in vivo.

  Diabetes 20100601

• Roles for Nox4 in the contractile response of bovine pulmonary arteries to hypoxia.

  American journal of physiology. Heart and circulatory physiology 20100601

• Increased ANG II sensitivity following recovery from acute kidney injury: role of oxidant stress in skeletal muscle resistance arteries.

  American journal of physiology. Regulatory, integrative and comparative physiology 20100601

• Oxidative stress and vascular function: implications for pharmacologic treatments.

  Current hypertension reports 20100601

• Why pleiotropic interventions are needed for Alzheimer's disease.

  Molecular neurobiology 20100601

• Apocynin activity in spontaneously hypertensive rats (SHR): preliminary studies in vivo.

  Veterinary research communications 20100601

• Requirement of NOX2 and reactive oxygen species for efficient RIG-I-mediated antiviral response through regulation of MAVS expression.

  PLoS pathogens 20100601

• Cigarette smoke particle-phase extract induces HO-1 expression in human tracheal smooth muscle cells: role of the c-Src/NADPH oxidase/MAPK/Nrf2 signaling pathway.

  Free radical biology & medicine 20100515

• Comparative effects of cilostazol and aspirin on the impairment of endothelium-dependent cerebral vasodilation caused by acute cigarette smoking in rats.

  Journal of thrombosis and thrombolysis 20100501

• The pentose phosphate pathway plays an essential role in supporting human sperm capacitation.

  Fertility and sterility 20100501

• Exposure of Toll-like receptors 4 to bacterial lipopolysaccharide (LPS) impairs human colonic smooth muscle cell function.

  Journal of cellular physiology 20100501

• The induction of reactive oxygen species and loss of mitochondrial Omi/HtrA2 is associated with S-nitrosoglutathione-induced apoptosis in human endothelial cells.

  Toxicology and applied pharmacology 20100501

• RhoA-Rho kinase signaling mediates endothelium- and endoperoxide-dependent contractile activities characteristic of hypertensive vascular dysfunction.

  American journal of physiology. Heart and circulatory physiology 20100501

• Hyperglycaemia-induced impairment of endothelium-dependent vasorelaxation in rat mesenteric arteries is mediated by intracellular methylglyoxal levels in a pathway dependent on oxidative stress.

  Diabetologia 20100501

• The biosynthesis of acetovanillone in tobacco cell-suspension cultures.

  Phytochemistry 20100501

• The Anrep effect requires transactivation of the epidermal growth factor receptor.

  The Journal of physiology 20100501

• Caloric restriction reverses high-fat diet-induced endothelial dysfunction and vascular superoxide production in C57Bl/6 mice.

  Heart and vessels 20100501

• [Antibacterial effect of autologous platelet-rich gel derived from health volunteers in vitro].

  Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery 20100501

• AMPKalpha2 deletion causes aberrant expression and activation of NAD(P)H oxidase and consequent endothelial dysfunction in vivo: role of 26S proteasomes.

  Circulation research 20100402

• Cyclic stretch downregulates arterial vascular connexin43 protein expression: an ex vivo study.

  Biomechanics and modeling in mechanobiology 20100401

• Losartan prevents portal hypertension-induced, redox-mediated endothelial dysfunction in the mesenteric artery in rats.

  Gastroenterology 20100401

• Cooperative induction of CXCL10 involves NADPH oxidase: Implications for HIV dementia.

  Glia 20100401

• Centrally administered lipopolysaccharide elicits sympathetic excitation via NAD(P)H oxidase-dependent mitogen-activated protein kinase signaling.

  Journal of hypertension 20100401

• Redox signaling via lipid raft clustering in homocysteine-induced injury of podocytes.

  Biochimica et biophysica acta 20100401

• PKC-alpha mediates flow-stimulated superoxide production in thick ascending limbs.

  American journal of physiology. Renal physiology 20100401

• 20-HETE-induced nitric oxide production in pulmonary artery endothelial cells is mediated by NADPH oxidase, H2O2, and PI3-kinase/Akt.

  American journal of physiology. Lung cellular and molecular physiology 20100401

• Unacylated ghrelin rescues endothelial progenitor cell function in individuals with type 2 diabetes.

  Diabetes 20100401

• Involvement of NADPH oxidase in age-associated cardiac remodeling.

  Journal of molecular and cellular cardiology 20100401

• Hypoxia sensing in the fetal chicken femoral artery is mediated by the mitochondrial electron transport chain.

  American journal of physiology. Regulatory, integrative and comparative physiology 20100401

• Roles of NADPH oxidases in cisplatin-induced reactive oxygen species generation and ototoxicity.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20100317

• Melanogenesis inhibitors from the desert plant Anastatica hierochuntica in B16 melanoma cells.

  Bioorganic & medicinal chemistry 20100315

• Brief exposure to carbon monoxide preconditions cardiomyogenic cells against apoptosis in ischemia-reperfusion.

  Biochemical and biophysical research communications 20100312

• Diapocynin versus apocynin as pretranscriptional inhibitors of NADPH oxidase and cytokine production by peripheral blood mononuclear cells.

  Biochemical and biophysical research communications 20100312

• Androgens induce oxidative stress and radiation resistance in prostate cancer cells though NADPH oxidase.

  Prostate cancer and prostatic diseases 20100301

• Prediction of solubility of drugs and other compounds in organic solvents.

  Journal of pharmaceutical sciences 20100301

• High glucose increases expression of cyclooxygenase-2, increases oxidative stress and decreases the generation of nitric oxide in mouse microvessel endothelial cells.

  Journal of cellular physiology 20100301

• Tumor necrosis factor induces matrix metalloproteinases in cardiomyocytes and cardiofibroblasts differentially via superoxide production in a PI3Kgamma-dependent manner.

  American journal of physiology. Cell physiology 20100301

• NOX2 is the primary source of angiotensin II-induced superoxide in the macula densa.

  American journal of physiology. Regulatory, integrative and comparative physiology 20100301

• Mechanism of neurodegeneration of neurons with mitochondrial DNA mutations.

  Brain : a journal of neurology 20100301

• Hydrogen peroxide generated from cardiac myocytes impacts metabolic dilation in coronary arterioles.

  International heart journal 20100301

• Potential mechanisms of low-sodium diet-induced cardiac disease: superoxide-NO in the heart.

  Circulation research 20100219

• NAD(P)H oxidase contributes to neurotoxicity in an excitotoxic/prooxidant model of Huntington's disease in rats: protective role of apocynin.

  Journal of neuroscience research 20100215

• Fluoride-containing bioactive glasses inhibit pentose phosphate oxidative pathway and glucose 6-phosphate dehydrogenase activity in human osteoblasts.

  Chemico-biological interactions 20100212

• Effect of apocynin on NADPH oxidase-mediated oxidative stress-LOX-1-eNOS pathway in human endothelial cells exposed to high glucose.

  European journal of pharmacology 20100210

• The effects of oxygen stresses on the development of features of severe retinopathy of prematurity: knowledge from the 50/10 OIR model.

  Documenta ophthalmologica. Advances in ophthalmology 20100201

• Antioxidants reverse age-related collateral growth impairment.

  Journal of vascular research 20100201

• Paraoxonase 2 (PON2) decreases high glucose-induced macrophage triglycerides (TG) accumulation, via inhibition of NADPH-oxidase and DGAT1 activity: studies in PON2-deficient mice.

  Atherosclerosis 20100201

• Apocynin decreases hydrogen peroxide and nitrate concentrations in exhaled breath in healthy subjects.

  Pulmonary pharmacology & therapeutics 20100201

• Modulation of paraoxonase 1 and protein N-homocysteinylation by leptin and the synthetic liver X receptor agonist T0901317 in the rat.

  The Journal of endocrinology 20100201

• Rac1 mediates NaCl-induced superoxide generation in the thick ascending limb.

  American journal of physiology. Renal physiology 20100201

• Role of NADPH oxidase-2 in lipopolysaccharide-induced matrix metalloproteinase expression and cell migration.

  Immunology and cell biology 20100201

• Refractory blood pressure in female SHR to increased oxidative stress is not mediated by NO or by upregulation of renal antioxidant enzymes.

  American journal of physiology. Regulatory, integrative and comparative physiology 20100201

• Reactive oxygen species and cyclooxygenase 2-derived thromboxane A2 reduce angiotensin II type 2 receptor vasorelaxation in diabetic rat resistance arteries.

  Hypertension (Dallas, Tex. : 1979) 20100201

• Protein kinase C-dependent NAD(P)H oxidase activation induced by type 1 diabetes in renal medullary thick ascending limb.

  Hypertension (Dallas, Tex. : 1979) 20100201

• Tumor necrosis factor-alpha: a possible priming agent for the polymorphonuclear leukocyte-reduced nicotinamide-adenine dinucleotide phosphate oxidase in hypertension.

  Hypertension (Dallas, Tex. : 1979) 20100201

• Apocynin attenuate spatial learning deficits and oxidative responses to intermittent hypoxia.

  Sleep medicine 20100201

• Leptin and the Regulation of Renal Sodium Handling and Renal Na-Transporting ATPases: Role in the Pathogenesis of Arterial Hypertension.

  Current cardiology reviews 20100201

• Induction of COX-2/PGE(2)/IL-6 is crucial for cigarette smoke extract-induced airway inflammation: Role of TLR4-dependent NADPH oxidase activation.

  Free radical biology & medicine 20100115

• Total body irradiation causes residual bone marrow injury by induction of persistent oxidative stress in murine hematopoietic stem cells.

  Free radical biology & medicine 20100115

• Ischemia-activated microglia induces neuronal injury via activation of gp91phox NADPH oxidase.

  Biochemical and biophysical research communications 20100115

• Ascorbate protects endothelial barrier function during septic insult: Role of protein phosphatase type 2A.

  Free radical biology & medicine 20100101

• Angiotensin II enhances hyperpolarization-activated currents in rat aortic baroreceptor neurons: involvement of superoxide.

  American journal of physiology. Cell physiology 20100101

• Vasomotor dysfunction in the thoracic aorta of Marfan syndrome is associated with accumulation of oxidative stress.

  Vascular pharmacology 20100101

• Endogenous reactive oxygen species are essential for proliferation of neural stem/progenitor cells.

  Neurochemistry international 20100101

• Rod and cone photoreceptor cells produce ROS in response to stress in a live retinal explant system.

  Molecular vision 20100101

• Mechanisms of tumor necrosis factor-alpha-induced interleukin-6 synthesis in glioma cells.

  Journal of neuroinflammation 20100101

• Apocynin restores endothelial dysfunction in streptozotocin diabetic rats through regulation of nitric oxide synthase and NADPH oxidase expressions.

  Journal of diabetes and its complications 20100101

• N-octanoyl dopamine, a non-hemodyanic dopamine derivative, for cell protection during hypothermic organ preservation.

  PloS one 20100101

• Oxidation of isoeugenol by salen complexes with bulky substituents.

  International journal of molecular sciences 20100101

• Preservation of kidney function with combined inhibition of NADPH oxidase and angiotensin-converting enzyme in diabetic nephropathy.

  American journal of nephrology 20100101

• Precursor of advanced glycation end products mediates ER-stress-induced caspase-3 activation of human dermal fibroblasts through NAD(P)H oxidase 4.

  PloS one 20100101

• Advanced oxidation protein products decrease expression of nephrin and podocin in podocytes via ROS-dependent activation of p38 MAPK.

  Science China. Life sciences 20100101

• NADPH Oxidase versus Mitochondria-Derived ROS in Glucose-Induced Apoptosis of Pericytes in Early Diabetic Retinopathy.

  Journal of ophthalmology 20100101

• Gp91phox (NOX2) in classically activated microglia exacerbates traumatic brain injury.

  Journal of neuroinflammation 20100101

• Role of NAD(P)H oxidase in superoxide generation and endothelial dysfunction in Goto-Kakizaki (GK) rats as a model of nonobese NIDDM.

  PloS one 20100101

• Hypoxia-inducible factor 1alpha determines gastric cancer chemosensitivity via modulation of p53 and NF-kappaB.

  PloS one 20100101

• Association of Toll-like receptor signaling and reactive oxygen species: a potential therapeutic target for posttrauma acute lung injury.

  Mediators of inflammation 20100101

• Advanced glycation end products, oxidative stress and diabetic nephropathy.

  Oxidative medicine and cellular longevity 20100101

• Reactive oxygen species are involved in regulating alpha1-adrenoceptor-activated vascular smooth muscle contraction.

  Journal of biomedical science 20100101

• Oxidant-NO dependent gene regulation in dogs with type I diabetes: impact on cardiac function and metabolism.

  Cardiovascular diabetology 20100101

• Kinin B1 receptor enhances the oxidative stress in a rat model of insulin resistance: outcome in hypertension, allodynia and metabolic complications.

  PloS one 20100101

• Anthrax lethal toxin suppresses murine cardiomyocyte contractile function and intracellular Ca2+ handling via a NADPH oxidase-dependent mechanism.

  PloS one 20100101

• Peroxynitrite mediates diabetes-induced endothelial dysfunction: possible role of Rho kinase activation.

  Experimental diabetes research 20100101

• Knockout of angiotensin 1-7 receptor Mas worsens the course of two-kidney, one-clip Goldblatt hypertension: roles of nitric oxide deficiency and enhanced vascular responsiveness to angiotensin II.

  Kidney & blood pressure research 20100101

• Methylglyoxal augments angiotensin II-induced contraction in rat isolated carotid artery.

  Journal of pharmacological sciences 20100101

• Molecular characteristics of Kraft-AQ pulping lignin fractionated by sequential organic solvent extraction.

  International journal of molecular sciences 20100101

• Reactive oxygen species enhance TLR10 expression in the human monocytic cell line THP-1.

  International journal of molecular sciences 20100101

• Characteristics of lignin from flax shives as affected by extraction conditions.

  International journal of molecular sciences 20100101

• Organic nitrates and nitrate resistance in diabetes: the role of vascular dysfunction and oxidative stress with emphasis on antioxidant properties of pentaerithrityl tetranitrate.

  Experimental diabetes research 20100101

• [NADPH oxidase controls EGF-induced proliferation via the ERK1/2-independent mechanism].

  Biofizika 20100101

• Insights into the development and treatment of cardiovascular disease: a role for animal models.

  The open cardiovascular medicine journal 20100101

• Signaling of reactive oxygen and nitrogen species in Diabetes mellitus.

  Oxidative medicine and cellular longevity 20100101

• Apocynin improves insulin resistance through suppressing inflammation in high-fat diet-induced obese mice.

  Mediators of inflammation 20100101

• Role of the mitochondrion in programmed necrosis.

  Frontiers in physiology 20100101

• A study of standardized extracts of Picrorhiza kurroa Royle ex Benth in experimental nonalcoholic fatty liver disease.

  Journal of Ayurveda and integrative medicine 20100101

• Low concentration of arsenic could induce caspase-3 mediated head kidney macrophage apoptosis with JNK-p38 activation in Clarias batrachus.

  Toxicology and applied pharmacology 20091215

• Effects of apocynin and losartan treatment on renal oxidative stress in a rat model of calcium oxalate nephrolithiasis.

  International urology and nephrology 20091201

• Reactive oxygen species in rostral ventrolateral medulla modulate cardiac sympathetic afferent reflex in rats.

  Acta physiologica (Oxford, England) 20091201

• Accumulation of advanced oxidation protein products induces podocyte apoptosis and deletion through NADPH-dependent mechanisms.

  Kidney international 20091201

• Urotensin II induces rat cardiomyocyte hypertrophy via the transient oxidization of Src homology 2-containing tyrosine phosphatase and transactivation of epidermal growth factor receptor.

  Molecular pharmacology 20091201

• Reactive oxygen species promote angiogenesis in the infarcted rat heart.

  International journal of experimental pathology 20091201

• Nitric oxide-mediated dilation of arterioles to intraluminal administration of aldosterone.

  Journal of cardiovascular pharmacology 20091201

• Antioxidant treatment with tempol and apocynin prevents endothelial dysfunction and development of renovascular hypertension.

  American journal of hypertension 20091201

• Abnormal nitric oxide production in aged rat mesenteric arteries is mediated by NAD(P)H oxidase-derived peroxide.

  American journal of physiology. Heart and circulatory physiology 20091201

• Renal proximal tubular reabsorption is reduced in adult spontaneously hypertensive rats: roles of superoxide and Na+/H+ exchanger 3.

  Hypertension (Dallas, Tex. : 1979) 20091201

• Calcium-independent phospholipase A2beta-Akt signaling is involved in lipopolysaccharide-induced NADPH oxidase 1 expression and foam cell formation.

  Journal of immunology (Baltimore, Md. : 1950) 20091201

• Asymmetric dimethylarginine damages connexin43-mediated endothelial gap junction intercellular communication.

  Biochemistry and cell biology = Biochimie et biologie cellulaire 20091201

• CK2 is a novel negative regulator of NADPH oxidase and a neuroprotectant in mice after cerebral ischemia.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20091125

• Episodic spinal serotonin receptor activation elicits long-lasting phrenic motor facilitation by an NADPH oxidase-dependent mechanism.

  The Journal of physiology 20091115

• Involvement of oxidative pathways in cytokine-induced secretory phospholipase A2-IIA in astrocytes.

  Neurochemistry international 20091101

• Stimulation of coronary collateral growth by granulocyte stimulating factor: role of reactive oxygen species.

  Arteriosclerosis, thrombosis, and vascular biology 20091101

• Involvement of NADPH oxidase and protein kinase C in endothelin-1-induced superoxide production in retinal microvessels.

  Experimental eye research 20091101

• The arachidonic acid effect on platelet nitric oxide level.

  Biochimica et biophysica acta 20091101

• Effects of acute and chronic endurance exercise on intracellular nitric oxide in putative endothelial progenitor cells: role of NAPDH oxidase.

  American journal of physiology. Heart and circulatory physiology 20091101

• Role of reactive oxygen species (ROS) in Mycobacterium bovis bacillus Calmette Guérin-mediated up-regulation of the human cathelicidin LL-37 in A549 cells.

  Microbial pathogenesis 20091101

• Translating the oxidative stress hypothesis into the clinic: NOX versus NOS.

  Journal of molecular medicine (Berlin, Germany) 20091101

• Myristic Acid, A Side Chain of Phorbol Myristate Acetate (PMA), Can Activate Human Polymorphonuclear Leukocytes to Produce Oxygen Radicals More Potently than PMA.

  Journal of clinical biochemistry and nutrition 20091101

• NADPH oxidases participate to doxorubicin-induced cardiac myocyte apoptosis.

  Biochemical and biophysical research communications 20091030

• Chemical interaction in the invasiveness of cogongrass (Imperata cylindrica (L.) Beauv.).

  Journal of agricultural and food chemistry 20091028

• NADPH oxidase and lipid raft-associated redox signaling are required for PCB153-induced upregulation of cell adhesion molecules in human brain endothelial cells.

  Toxicology and applied pharmacology 20091015

• NOX2 inhibition with apocynin worsens stroke outcome in aged rats.

  Brain research 20091006

• Amelioration of adjuvant induced arthritis by apocynin.

  Phytotherapy research : PTR 20091001

• Dyslipidemia-induced neuropathy in mice: the role of oxLDL/LOX-1.

  Diabetes 20091001

• Rac1 is required for cardiomyocyte apoptosis during hyperglycemia.

  Diabetes 20091001

• Serotonin produces monoamine oxidase-dependent oxidative stress in human heart valves.

  American journal of physiology. Heart and circulatory physiology 20091001

• The NADPH oxidase inhibitor diphenyleneiodonium is also a potent inhibitor of cholinesterases and the internal Ca(2+) pump.

  British journal of pharmacology 20091001

• [Chemical constituents of flowers from Polygonum orientale].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20091001

• [Effects of NADPH oxidase inhibition on cardiac function and myocardial calcium regulatory proteins in rabbits with heart failure].

  Zhonghua xin xue guan bing za zhi 20091001

• Apocynin improves endothelial function and prevents the development of hypertension in fructose fed rat.

  Indian journal of pharmacology 20091001

• Hypoxia up-regulates CD36 expression and function via hypoxia-inducible factor-1- and phosphatidylinositol 3-kinase-dependent mechanisms.

  The Journal of biological chemistry 20090925

• Prolonged exposure to ammonia increases extracellular glutamate in cultured rat astrocytes.

  Neuroscience letters 20090922

• In vivo imaging of reactive oxygen and nitrogen species in inflammation using the luminescent probe L-012.

  Free radical biology & medicine 20090915

• Aryl hydrocarbon receptor-dependent induction of the NADPH oxidase subunit NCF1/p47 phox expression leading to priming of human macrophage oxidative burst.

  Free radical biology & medicine 20090915

• Activation of protease calpain by oxidized and glycated LDL increases the degradation of endothelial nitric oxide synthase.

  Journal of cellular and molecular medicine 20090901

• Urotensin II-induced endothelin-1 expression and cell proliferation via epidermal growth factor receptor transactivation in rat aortic smooth muscle cells.

  Atherosclerosis 20090901

• The role of NADPH oxidase 1-derived reactive oxygen species in paraquat-mediated dopaminergic cell death.

  Antioxidants & redox signaling 20090901

• Treatment of spontaneously hypertensive rats with rosiglitazone ameliorates cardiovascular pathophysiology via antioxidant mechanisms in the vasculature.

  American journal of physiology. Endocrinology and metabolism 20090901

• Novel pathway of endothelin-1 and reactive oxygen species in coronary vasospasm with endothelial dysfunction.

  Coronary artery disease 20090901

• Run for your life: exercise, oxidative stress and the ageing endothelium.

  The Journal of physiology 20090901

• Dengue hemorrhage in a mouse model.

  Annals of the New York Academy of Sciences 20090901

• A possible mechanism for the apocynin-induced nitric oxide accumulation in plants.

  Plant signaling & behavior 20090901

• 4-Hydr-oxy-3-meth-oxy-5-nitro-aceto-phenone (5-nitro-apocynin).

  Acta crystallographica. Section E, Structure reports online 20090901

• Apocynin-induced nitric oxide production confers antioxidant protection in maize leaves.

  Journal of plant physiology 20090815

• Enhanced ROS production and redox signaling with combined arsenite and UVA exposure: contribution of NADPH oxidase.

  Free radical biology & medicine 20090815

• Endothelial and potassium channel dependent modulation of noradrenergic vasoconstriction in the pig radial artery.

  European journal of pharmacology 20090815

• Involvement of NOX2 in the development of behavioral and pathologic alterations in isolated rats.

  Biological psychiatry 20090815

• High-cholesterol diet augments endothelial dysfunction via elevated oxidative stress and reduced tetrahydrobiopterin in Ins2(Akita) mice, an autosomal dominant mutant type 1 diabetic model.

  Clinical and experimental pharmacology & physiology 20090801

• Rac1 mediates sex difference in cardiac tumor necrosis factor-alpha expression via NADPH oxidase-ERK1/2/p38 MAPK pathway in endotoxemia.

  Journal of molecular and cellular cardiology 20090801

• Resveratrol improves endothelial function: role of TNF{alpha} and vascular oxidative stress.

  Arteriosclerosis, thrombosis, and vascular biology 20090801

• NADPH oxidase plays a central role in cone cell death in retinitis pigmentosa.

  Journal of neurochemistry 20090801

• NADPH oxidase-derived reactive oxygen species in skeletal muscle modulates the exercise pressor reflex.

  Journal of applied physiology (Bethesda, Md. : 1985) 20090801

• 20-HETE can act as a nonhypoxic regulator of HIF-1alpha in human microvascular endothelial cells.

  American journal of physiology. Heart and circulatory physiology 20090801

• mu-opioid receptor-stimulated synthesis of reactive oxygen species is mediated via phospholipase D2.

  Journal of neurochemistry 20090801

• Beneficial effect of propofol on arterial adenosine triphosphate-sensitive K+ channel function impaired by thromboxane.

  Anesthesiology 20090801

• Overexpression of HO-1 protects against TNF-alpha-mediated airway inflammation by down-regulation of TNFR1-dependent oxidative stress.

  The American journal of pathology 20090801

• Radiation nephropathy is not mitigated by antagonists of oxidative stress.

  Radiation research 20090801

• [Advanced glycation end products induce expression of PAI-1 in cultured human proximal tubular epithelial cells through NADPH oxidase dependent pathway].

  Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20090801

• Role of protein kinase C in NADPH oxidase derived O2*(-)-mediated regulation of KV-LVOCC axis under U46619 induced increase in [Ca2+]i in pulmonary smooth muscle cells.

  Archives of biochemistry and biophysics 20090715

• Inhibition of human vascular NADPH oxidase by apocynin derived oligophenols.

  Bioorganic & medicinal chemistry 20090715

• The role of supplemental oxygen and JAK/STAT signaling in intravitreous neovascularization in a ROP rat model.

  Investigative ophthalmology & visual science 20090701

• The role of nitric oxide and reactive oxygen species in the positive inotropic response to mechanical stretch in the mammalian myocardium.

  Biochimica et biophysica acta 20090701

• Voluntary wheel running restores endothelial function in conduit arteries of old mice: direct evidence for reduced oxidative stress, increased superoxide dismutase activity and down-regulation of NADPH oxidase.

  The Journal of physiology 20090701

• Inhibition of NADPH oxidase is neuroprotective after ischemia-reperfusion.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20090701

• Increased superoxide production contributes to the impaired angiogenesis of fetal pulmonary arteries with in utero pulmonary hypertension.

  American journal of physiology. Lung cellular and molecular physiology 20090701

• Increased myocardial NAD(P)H oxidase-derived superoxide causes the exacerbation of postinfarct heart failure in type 2 diabetes.

  American journal of physiology. Heart and circulatory physiology 20090701

• In vitro and in vivo studies of 6,8-(diaryl)imidazo[1,2-a]pyrazin-3(7H)-ones as new antioxidants.

  Bioorganic & medicinal chemistry 20090701

• NADPH oxidase is the primary source of superoxide induced by NMDA receptor activation.

  Nature neuroscience 20090701

• Mechanism of diastolic stiffening of the failing myocardium and its prevention by angiotensin receptor and calcium channel blockers.

  Journal of cardiovascular pharmacology 20090701

• [NADPH oxidase-derived reactive oxygen species involved in angiotensin II-induced monocyte chemoattractant protein-1 expression in mesangial cells].

  Zhonghua bing li xue za zhi = Chinese journal of pathology 20090701

• 2,2-Dibromo-1-(4-hydr-oxy-3-methoxy-phen-yl)ethanone.

  Acta crystallographica. Section E, Structure reports online 20090701

• Effects of co-administration of dietary sodium arsenite and an NADPH oxidase inhibitor on the rat bladder epithelium.

  Toxicology 20090630

• Relationship between calcium release and NADPH oxidase inhibition in human neutrophils.

  Biochemical and biophysical research communications 20090619

• Activation-dependent stabilization of the human thromboxane receptor: role of reactive oxygen species.

  Journal of lipid research 20090601

• NAD(P)H oxidase-dependent regulation of CCL2 production during retinal inflammation.

  Investigative ophthalmology & visual science 20090601

• ADMA injures the glomerular filtration barrier: role of nitric oxide and superoxide.

  American journal of physiology. Renal physiology 20090601

• Aldosterone-induced mesangial cell proliferation is mediated by EGF receptor transactivation.

  American journal of physiology. Renal physiology 20090601

• Dependence of cathepsin L-induced coronary endothelial dysfunction upon activation of NAD(P)H oxidase.

  Microvascular research 20090601

• Angiotensin II-induced increase in myocardial distensibility and its modulation by the endocardial endothelium in the rabbit heart.

  Experimental physiology 20090601

• Feed-forward signaling of TNF-alpha and NF-kappaB via IKK-beta pathway contributes to insulin resistance and coronary arteriolar dysfunction in type 2 diabetic mice.

  American journal of physiology. Heart and circulatory physiology 20090601

• Oxidative-nitrosative stress in a rabbit pup model of germinal matrix hemorrhage: role of NAD(P)H oxidase.

  Stroke 20090601

• Redox-sensitive Akt and Src regulate coronary collateral growth in metabolic syndrome.

  American journal of physiology. Heart and circulatory physiology 20090601

• Atorvastatin prevents endothelial dysfunction in mesenteric arteries from spontaneously hypertensive rats: role of cyclooxygenase 2-derived contracting prostanoids.

  Hypertension (Dallas, Tex. : 1979) 20090601

• Palmitate induces insulin resistance in H4IIEC3 hepatocytes through reactive oxygen species produced by mitochondria.

  The Journal of biological chemistry 20090529

• Activation of ROS/NF-kappaB and Ca2+/CaM kinase II are necessary for VCAM-1 induction in IL-1beta-treated human tracheal smooth muscle cells.

  Toxicology and applied pharmacology 20090515

• Red wine polyphenols prevent acceleration of neovascularization by angiotensin II in the ischemic rat hindlimb.

  The Journal of pharmacology and experimental therapeutics 20090501

• Bradykinin-induced dilation of human coronary arterioles requires NADPH oxidase-derived reactive oxygen species.

  Arteriosclerosis, thrombosis, and vascular biology 20090501

• NADPH oxidase activity is necessary for acute intermittent hypoxia-induced phrenic long-term facilitation.

  The Journal of physiology 20090501

• Oxidative stress impairs vasorelaxation induced by the soluble guanylyl cyclase activator BAY 41-2272 in spontaneously hypertensive rats.

  American journal of hypertension 20090501

• Antioxidant treatment reduces matrix metalloproteinase-2-induced vascular changes in renovascular hypertension.

  Free radical biology & medicine 20090501

• Vanillin suppresses metastatic potential of human cancer cells through PI3K inhibition and decreases angiogenesis in vivo.

  Journal of agricultural and food chemistry 20090422

• Acrolein activates matrix metalloproteinases by increasing reactive oxygen species in macrophages.

  Toxicology and applied pharmacology 20090415

• An in vitro screening cascade to identify neuroprotective antioxidants in ALS.

  Free radical biology & medicine 20090415

• Kidney androgen-regulated protein transgenic mice show hypertension and renal alterations mediated by oxidative stress.

  Circulation 20090414

• RAGE-induced cytosolic ROS promote mitochondrial superoxide generation in diabetes.

  Journal of the American Society of Nephrology : JASN 20090401

• Angiotensin II inhibits the Na+-K+ pump via PKC-dependent activation of NADPH oxidase.

  American journal of physiology. Cell physiology 20090401

• Apocynin attenuates diaphragm oxidative stress and protease activation during prolonged mechanical ventilation.

  Critical care medicine 20090401

• Cigarette smoke extract induces cytosolic phospholipase A2 expression via NADPH oxidase, MAPKs, AP-1, and NF-kappaB in human tracheal smooth muscle cells.

  Free radical biology & medicine 20090401

• Cocaine and human immunodeficiency virus type 1 gp120 mediate neurotoxicity through overlapping signaling pathways.

  Journal of neurovirology 20090401

• Chronic production of peroxynitrite in the vascular wall impairs vasorelaxation function in SHR/NDmcr-cp rats, an animal model of metabolic syndrome.

  Journal of pharmacological sciences 20090401

• Cilostazol Attenuates 4-hydroxynonenal-enhanced CD36 Expression on Murine Macrophages via Inhibition of NADPH Oxidase-derived Reactive Oxygen Species Production.

  The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 20090401

• Age-accelerated atherosclerosis correlates with failure to upregulate antioxidant genes.

  Circulation research 20090327

• NADPH oxidase in bone marrow-derived cells mediates pulmonary ischemia-reperfusion injury.

  American journal of respiratory cell and molecular biology 20090301

• Role of NADPH oxidase in retinal microvascular permeability increase by RAGE activation.

  Investigative ophthalmology & visual science 20090301

• INO-4885 [5,10,15,20-tetra[N-(benzyl-4'-carboxylate)-2-pyridinium]-21H,23H-porphine iron(III) chloride], a peroxynitrite decomposition catalyst, protects the heart against reperfusion injury in mice.

  The Journal of pharmacology and experimental therapeutics 20090301

• Septic pulmonary microvascular endothelial cell injury: role of alveolar macrophage NADPH oxidase.

  American journal of physiology. Lung cellular and molecular physiology 20090301

• Nox4 NADPH oxidase mediates oxidative stress and apoptosis caused by TNF-alpha in cerebral vascular endothelial cells.

  American journal of physiology. Cell physiology 20090301

• Attenuation of lipopolysaccharide-induced oxidative stress and apoptosis in fetal pulmonary artery endothelial cells by hypoxia.

  Free radical biology & medicine 20090301

• Ketohexokinase-dependent metabolism of fructose induces proinflammatory mediators in proximal tubular cells.

  Journal of the American Society of Nephrology : JASN 20090301

• NADPH oxidase contributes to coronary endothelial dysfunction in the failing heart.

  American journal of physiology. Heart and circulatory physiology 20090301

• Platelet and leukocyte adhesion in the microvasculature at the cerebral surface immediately after subarachnoid hemorrhage.

  Neurosurgery 20090301

• Nitric oxide synthase-dependent responses of the basilar artery during acute infusion of nicotine.

  Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20090301

• Acute hyperglycemia enhances oxidative stress and exacerbates myocardial infarction by activating nicotinamide adenine dinucleotide phosphate oxidase during reperfusion.

  The Journal of thoracic and cardiovascular surgery 20090301

• Role of oxidative stress in the natriuresis induced by central administration of angiotensin II.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20090301

• Sympathoexcitation by oxidative stress in the brain mediates arterial pressure elevation in obesity-induced hypertension.

  Circulation 20090224

• TNF-induced mitochondrial damage: a link between mitochondrial complex I activity and left ventricular dysfunction.

  Free radical biology & medicine 20090215

• Suppression of retinal peroxisome proliferator-activated receptor gamma in experimental diabetes and oxygen-induced retinopathy: role of NADPH oxidase.

  Investigative ophthalmology & visual science 20090201

• Inducible nitric oxide synthase is involved in endothelial dysfunction of mesenteric small arteries from hypothyroid rats.

  Endocrinology 20090201

• Role of neuronal NO synthase in regulating vascular superoxide levels and mitogen-activated protein kinase phosphorylation.

  Cardiovascular research 20090201

• Hyperbaric oxygen stimulates vasculogenic stem cell growth and differentiation in vivo.

  Journal of applied physiology (Bethesda, Md. : 1985) 20090201

• Uric acid inhibits placental system A amino acid uptake.

  Placenta 20090201

• Effects of NADPH oxidase inhibitor on diabetic nephropathy in OLETF rats: the role of reducing oxidative stress in its protective property.

  Diabetes research and clinical practice 20090201

• Enhanced transformation of malachite green by laccase of Ganoderma lucidum in the presence of natural phenolic compounds.

  Applied microbiology and biotechnology 20090201

• Reduction of cerebral infarct volume by apocynin requires pretreatment and is absent in Nox2-deficient mice.

  British journal of pharmacology 20090201

• [Angiotensin II increases ROS production in cardiac fibroblasts by inducing p22phox over-expression].

  Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20090201

• NADPH oxidase and hydrogen peroxide mediate insulin-induced calcium increase in skeletal muscle cells.

  The Journal of biological chemistry 20090123

• MK801 blocks hypoxic blood-brain-barrier disruption and leukocyte adhesion.

  Neuroscience letters 20090116

• Iron-enhanced paraquat-mediated dopaminergic cell death due to increased oxidative stress as a consequence of microglial activation.

  Free radical biology & medicine 20090115

• Quercetin inhibits vascular superoxide production induced by endothelin-1: Role of NADPH oxidase, uncoupled eNOS and PKC.

  Atherosclerosis 20090101

• Inhibition of reactive oxygen species attenuates aneurysm formation in a murine model.

  Atherosclerosis 20090101

• Oxidative stress mediates protein kinase C activation and advanced glycation end product formation in a mesangial cell model of diabetes and high protein diet.

  American journal of nephrology 20090101

• Peroxynitrite-dependent activation of protein phosphatase type 2A mediates microvascular endothelial barrier dysfunction.

  Cardiovascular research 20090101

• Normalizing NADPH oxidase contributes to attenuating diabetic nephropathy by the dual endothelin receptor antagonist CPU0213 in rats.

  American journal of nephrology 20090101

• Platelet-derived growth factor BB stimulates vasculogenesis of embryonic stem cell-derived endothelial cells by calcium-mediated generation of reactive oxygen species.

  Cardiovascular research 20090101

• Hypertension increases contractile responses to hydrogen peroxide in resistance arteries through increased thromboxane A2, Ca2+, and superoxide anion levels.

  The Journal of pharmacology and experimental therapeutics 20090101

• Obesity-related upregulation of monocyte chemotactic factors in adipocytes: involvement of nuclear factor-kappaB and c-Jun NH2-terminal kinase pathways.

  Diabetes 20090101

• H2S protects against methionine-induced oxidative stress in brain endothelial cells.

  Antioxidants & redox signaling 20090101

• Apocynin attenuates tubular apoptosis and tubulointerstitial fibrosis in transgenic mice independent of hypertension.

  Kidney international 20090101

• Nox-2 is a modulator of fibrogenesis in kidney allografts.

  American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20090101

• Role of NOX2 in the regulation of afferent arteriole responsiveness.

  American journal of physiology. Regulatory, integrative and comparative physiology 20090101

• NADPH oxidase has a directional response to shear stress.

  American journal of physiology. Heart and circulatory physiology 20090101

• Regulation of coronary vascular tone via redox modulation in the alpha1-adrenergic-angiotensin-endothelin axis of the myocardium.

  American journal of physiology. Heart and circulatory physiology 20090101

• p38 MAPK contributes to angiotensin II-induced COX-2 expression in aortic fibroblasts from normotensive and hypertensive rats.

  Journal of hypertension 20090101

• Effect of chronic apocynin treatment on nitric oxide and reactive oxygen species production in borderline and spontaneous hypertension.

  Pharmacological reports : PR 20090101

• IL-6 mediated degeneration of forebrain GABAergic interneurons and cognitive impairment in aged mice through activation of neuronal NADPH oxidase.

  PloS one 20090101

• Expression of glutaredoxin-1 in nasal polyps and airway epithelial cells.

  American journal of rhinology & allergy 20090101

• Direct aldosterone action as a profibrotic factor via ROS-mediated SGK1 in peritoneal fibroblasts.

  Kidney & blood pressure research 20090101

• Inhibition of L-type Ca(2+) channels by carbon monoxide.

  Advances in experimental medicine and biology 20090101

• Reduction of oxidative stress does not attenuate the development of angiotensin II-dependent hypertension in Ren-2 transgenic rats.

  Vascular pharmacology 20090101

• Advanced oxidation protein products inhibit proliferation and differentiation of rat osteoblast-like cells via NF-kappaB pathway.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20090101

• NAD(P)H oxidase isoform Nox2 plays a prosurvival role in human leukaemia cells.

  Free radical research 20090101

• Bench-to-bedside review: Diaphragm muscle function in disuse and acute high-dose corticosteroid treatment.

  Critical care (London, England) 20090101

• NADPH oxidase mediates beta-amyloid peptide-induced activation of ERK in hippocampal organotypic cultures.

  Molecular brain 20090101

• Nitric oxide and superoxide dismutase modulate endothelial progenitor cell function in type 2 diabetes mellitus.

  Cardiovascular diabetology 20090101

• Static pressure promotes rat aortic smooth muscle cell proliferation via upregulation of volume-regulated chloride channel.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20090101

• NADPH oxidase-derived ROS contributes to upregulation of TRPC6 expression in puromycin aminonucleoside-induced podocyte injury.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20090101

• Cigarette smoking blocks the protective expression of Nrf2/ARE pathway in peripheral mononuclear cells of young heavy smokers favouring inflammation.

  PloS one 20090101

• Non-cell-autonomous effect of human SOD1 G37R astrocytes on motor neurons derived from human embryonic stem cells.

  Cell stem cell 20081204

• Pharmacological evidence for the stimulation of NADPH oxidase by P2X(7) receptors in mouse submandibular glands.

  Purinergic signalling 20081201

• Renal antioxidant enzymes and glutathione redox status in leptin-induced hypertension.

  Molecular and cellular biochemistry 20081201

• Normobaric hyperoxia inhibits NADPH oxidase-mediated matrix metalloproteinase-9 induction in cerebral microvessels in experimental stroke.

  Journal of neurochemistry 20081201

• Role of TNF-alpha-induced reactive oxygen species in endothelial dysfunction during reperfusion injury.

  American journal of physiology. Heart and circulatory physiology 20081201

• NADPH oxidase contributes to renal damage and dysfunction in Dahl salt-sensitive hypertension.

  American journal of physiology. Regulatory, integrative and comparative physiology 20081201

• Synergistic effect of laccase mediators on pentachlorophenol removal by Ganoderma lucidum laccase.

  Applied microbiology and biotechnology 20081201

• Salvage of nonischemic control lung from injury by unilateral ischemic lung with apocynin, a nicotinamide adenine dinucleotide phosphate (NADPH) oxidase inhibitor, in isolated perfused rat lung.

  Translational research : the journal of laboratory and clinical medicine 20081201

• Glucose and NADPH oxidase drive neuronal superoxide formation in stroke.

  Annals of neurology 20081201

• Expression of NAD(P)H oxidase subunits and their contribution to cardiovascular damage in aldosterone/salt-induced hypertensive rat.

  Journal of Korean medical science 20081201

• [Effect of NADPH oxidase activity inhibitor apocynin on blood pressure in rats exposed to chronic intermittent hypoxia and the possible mechanisms].

  Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20081201

• Neurotoxic activation of microglia is promoted by a nox1-dependent NADPH oxidase.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20081112

• Homocysteine and copper interact to promote type 5 phosphodiesterase expression in rabbit cavernosal smooth muscle cells.

  Asian journal of andrology 20081101

• Apocynin-induced vasodilation involves Rho kinase inhibition but not NADPH oxidase inhibition.

  Cardiovascular research 20081101

• Hypoxia activates NADPH oxidase to increase [ROS]i and [Ca2+]i through the mitochondrial ROS-PKCepsilon signaling axis in pulmonary artery smooth muscle cells.

  Free radical biology & medicine 20081101

• Superoxide from NADPH oxidase upregulates type 5 phosphodiesterase in human vascular smooth muscle cells: inhibition with iloprost and NONOate.

  British journal of pharmacology 20081101

• Excess salt causes cerebral neuronal apoptosis and inflammation in stroke-prone hypertensive rats through angiotensin II-induced NADPH oxidase activation.

  Stroke 20081101

• Diabetes induces pulmonary artery endothelial dysfunction by NADPH oxidase induction.

  American journal of physiology. Lung cellular and molecular physiology 20081101

• Amyloid-beta peptide induces temporal membrane biphasic changes in astrocytes through cytosolic phospholipase A2.

  Biochimica et biophysica acta 20081101

• Reactive oxygen species from NADPH oxidase contribute to altered pulmonary vascular responses in piglets with chronic hypoxia-induced pulmonary hypertension.

  American journal of physiology. Lung cellular and molecular physiology 20081101

• Regulation of globular adiponectin-induced apoptosis by reactive oxygen/nitrogen species in RAW264 macrophages.

  Free radical biology & medicine 20081101

• Microsomal prostaglandin synthase-1-derived prostaglandin E2 protects against angiotensin II-induced hypertension via inhibition of oxidative stress.

  Hypertension (Dallas, Tex. : 1979) 20081101

• ADMA impairs nitric oxide-mediated arteriolar function due to increased superoxide production by angiotensin II-NAD(P)H oxidase pathway.

  Hypertension (Dallas, Tex. : 1979) 20081101

• Uric acid stimulates endothelin-1 gene expression associated with NADPH oxidase in human aortic smooth muscle cells.

  Acta pharmacologica Sinica 20081101

• Platelets stimulate airway smooth muscle cell proliferation through mechanisms involving 5-lipoxygenase and reactive oxygen species.

  Platelets 20081101

• Effects of dietary sodium on reactive oxygen species formation and endothelial dysfunction in low-density lipoprotein receptor-deficient mice on high-fat diet.

  Heart and vessels 20081101

• Hemin-induced necroptosis involves glutathione depletion in mouse astrocytes.

  Free radical biology & medicine 20081015

• iNOS expression requires NADPH oxidase-dependent redox signaling in microvascular endothelial cells.

  Journal of cellular physiology 20081001

• Sequential release of nitric oxide, zinc, and superoxide in hypoglycemic neuronal death.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20081001

• Oxidative stress mediates cardiac fibrosis by enhancing transforming growth factor-beta1 in hypertensive rats.

  Molecular and cellular biochemistry 20081001

• Air pollution exposure potentiates hypertension through reactive oxygen species-mediated activation of Rho/ROCK.

  Arteriosclerosis, thrombosis, and vascular biology 20081001

• The alpha1D-adrenergic receptor induces vascular smooth muscle apoptosis via a p53-dependent mechanism.

  Molecular pharmacology 20081001

• Perivascular nitric oxide and superoxide in neonatal cerebral hypoxia-ischemia.

  American journal of physiology. Heart and circulatory physiology 20081001

• Intermittent hypoxia has organ-specific effects on oxidative stress.

  American journal of physiology. Regulatory, integrative and comparative physiology 20081001

• Role of oxidative stress in multiparity-induced endothelial dysfunction.

  American journal of physiology. Heart and circulatory physiology 20081001

• Lipoteichoic acid induces HO-1 expression via the TLR2/MyD88/c-Src/NADPH oxidase pathway and Nrf2 in human tracheal smooth muscle cells.

  Journal of immunology (Baltimore, Md. : 1950) 20081001

• Classical inhibitors of NOX NAD(P)H oxidases are not specific.

  Current drug metabolism 20081001

• Alternation of retinoic acid induced neural differentiation of P19 embryonal carcinoma cells by reduction of reactive oxygen species intracellular production.

  Neuro endocrinology letters 20081001

• Neovascularization in an arterio-venous loop-containing tissue engineering chamber: role of NADPH oxidase.

  Journal of cellular and molecular medicine 20081001

• Taxol induces oxidative neuronal cell death by enhancing the activity of NADPH oxidase in mouse cortical cultures.

  Neuroscience letters 20080926

• The non-provitamin A carotenoid, lutein, inhibits NF-kappaB-dependent gene expression through redox-based regulation of the phosphatidylinositol 3-kinase/PTEN/Akt and NF-kappaB-inducing kinase pathways: role of H(2)O(2) in NF-kappaB activation.

  Free radical biology & medicine 20080915

• Blockade of neuronal nitric oxide synthase reduces cone cell death in a model of retinitis pigmentosa.

  Free radical biology & medicine 20080915

• Angiotensin II enhances EGF receptor expression levels via ROS formation in HaCaT cells.

  Journal of dermatological science 20080901

• NO and PGI(2) in coronary endothelial dysfunction in transgenic mice with dilated cardiomyopathy.

  Basic research in cardiology 20080901

• Type I collagen induces tissue factor expression and matrix metalloproteinase 9 production in human primary monocytes through a redox-sensitive pathway.

  Journal of thrombosis and haemostasis : JTH 20080901

• Cyclooxygenase 2-selective and nonselective nonsteroidal anti-inflammatory drugs induce oxidative stress by up-regulating vascular NADPH oxidases.

  The Journal of pharmacology and experimental therapeutics 20080901

• Low mercury concentrations cause oxidative stress and endothelial dysfunction in conductance and resistance arteries.

  American journal of physiology. Heart and circulatory physiology 20080901

• NAD(P)H oxidase-derived peroxide mediates elevated basal and impaired flow-induced NO production in SHR mesenteric arteries in vivo.

  American journal of physiology. Heart and circulatory physiology 20080901

• Maturation-induces endothelial dysfunction via vascular inflammation in diabetic mice.

  Basic research in cardiology 20080901

• Activation of microglia with zymosan promotes excitatory amino acid release via volume-regulated anion channels: the role of NADPH oxidases.

  Journal of neurochemistry 20080901

• Intracellular pH regulates superoxide production by the macula densa.

  American journal of physiology. Renal physiology 20080901

• Roles of phosphatidylinositol 3-kinase-Akt and NADPH oxidase in adenosine 5'-triphosphate-sensitive K+ channel function impaired by high glucose in the human artery.

  Hypertension (Dallas, Tex. : 1979) 20080901

• Increased superoxide contributes to enhancement of vascular contraction in Ins2(Akita) diabetic mice, an autosomal dominant mutant model.

  Clinical and experimental pharmacology & physiology 20080901

• The NADPH oxidase is involved in lipopolysaccharide-mediated motor neuron injury.

  Brain research 20080821

• The positive inotropic effect of endothelin-1 is mediated by mitochondrial reactive oxygen species.

  Life sciences 20080815

• Reversal of oxidative stress-induced anxiety by inhibition of phosphodiesterase-2 in mice.

  The Journal of pharmacology and experimental therapeutics 20080801

• Aldosterone and angiotensin II synergistically stimulate migration in vascular smooth muscle cells through c-Src-regulated redox-sensitive RhoA pathways.

  Arteriosclerosis, thrombosis, and vascular biology 20080801

• Diesel exhaust particles induce oxidative stress, proinflammatory signaling, and P-glycoprotein up-regulation at the blood-brain barrier.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20080801

• Oxidative stress plays a permissive role in alpha2-adrenoceptor-mediated events in immortalized SHR proximal tubular epithelial cells.

  Molecular and cellular biochemistry 20080801

• Ammonia induces RNA oxidation in cultured astrocytes and brain in vivo.

  Hepatology (Baltimore, Md.) 20080801

• First evidence for a crosstalk between mitochondrial and NADPH oxidase-derived reactive oxygen species in nitroglycerin-triggered vascular dysfunction.

  Antioxidants & redox signaling 20080801

• An interleukin-6-neutralizing antibody prevents cyclosporine-induced nephrotoxicity in mice.

  The Journal of surgical research 20080801

• Differential mechanisms of angiotensin II and PDGF-BB on migration and proliferation of coronary artery smooth muscle cells.

  Journal of molecular and cellular cardiology 20080801

• Superoxide-dependent cathepsin activation is associated with hypertensive myocardial remodeling and represents a target for angiotensin II type 1 receptor blocker treatment.

  The American journal of pathology 20080801

• Septic impairment of capillary blood flow requires nicotinamide adenine dinucleotide phosphate oxidase but not nitric oxide synthase and is rapidly reversed by ascorbate through an endothelial nitric oxide synthase-dependent mechanism.

  Critical care medicine 20080801

• Differential effect of sulfonylureas on production of reactive oxygen species and apoptosis in cultured pancreatic beta-cell line, MIN6.

  Metabolism: clinical and experimental 20080801

• Superoxide anion mediates angiotensin II-induced potentiation of contractile response to sympathetic stimulation.

  European journal of pharmacology 20080728

• Role of oxidant stress on AT1 receptor expression in neurons of rabbits with heart failure and in cultured neurons.

  Circulation research 20080718

• Redox-sensitive signaling by angiotensin II involves oxidative inactivation and blunted phosphorylation of protein tyrosine phosphatase SHP-2 in vascular smooth muscle cells from SHR.

  Circulation research 20080718

• Role of superoxide and hydrogen peroxide in hypertension induced by an antagonist of adenosine receptors.

  European journal of pharmacology 20080707

• Role of NADPH oxidase in retinal vascular inflammation.

  Investigative ophthalmology & visual science 20080701

• Urokinase plasminogen activator upregulates paraoxonase 2 expression in macrophages via an NADPH oxidase-dependent mechanism.

  Arteriosclerosis, thrombosis, and vascular biology 20080701

• The role of the methoxyphenol apocynin, a vascular NADPH oxidase inhibitor, as a chemopreventative agent in the potential treatment of cardiovascular diseases.

  Current vascular pharmacology 20080701

• Is cardiac hypertrophy in spontaneously hypertensive rats the cause or the consequence of oxidative stress?

  Hypertension research : official journal of the Japanese Society of Hypertension 20080701

• Apocynin improves outcome in experimental stroke with a narrow dose range.

  Neuroscience 20080623

• Fluvastatin prevents glutamate-induced blood-brain-barrier disruption in vitro.

  Life sciences 20080620

• Bioavailability of apocynin through its conversion to glycoconjugate but not to diapocynin.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20080601

• Effect of resveratrol, tyrosol and beta-sitosterol on oxidised low-density lipoprotein-stimulated oxidative stress, arachidonic acid release and prostaglandin E2 synthesis by RAW 264.7 macrophages.

  The British journal of nutrition 20080601

• Kidney fibrosis in hypertensive rats: role of oxidative stress.

  American journal of nephrology 20080601

• Tumour necrosis factor alpha upregulates platelet CD40L in patients with heart failure.

  Cardiovascular research 20080601

• Oxidative stress and COX cause hyper-responsiveness in vascular smooth muscle of the femoral artery from diabetic rats.

  British journal of pharmacology 20080601

• Rho-kinase inhibitor and nicotinamide adenine dinucleotide phosphate oxidase inhibitor prevent impairment of endothelium-dependent cerebral vasodilation by acute cigarette smoking in rats.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20080601

• Zinc triggers microglial activation.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20080528

• Heparin-binding epidermal growth factor-like growth factor signaling in flow-induced arterial remodeling.

  Circulation research 20080523

• Protective effects of apocynin and allopurinol on ischemia/reperfusion-induced liver injury in mice.

  World journal of gastroenterology 20080514

• Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica.

  Science (New York, N.Y.) 20080502

• Reactive oxygen species produced up- or downstream of calcium influx regulate proinflammatory mediator release from mast cells: role of NADPH oxidase and mitochondria.

  Biochimica et biophysica acta 20080501

• Influence of chronic alcohol consumption on inward rectifier potassium channels in cerebral arterioles.

  Microvascular research 20080501

• The NADPH oxidase inhibitor apocynin induces nitric oxide synthesis via oxidative stress.

  Toxicology and applied pharmacology 20080501

• 20-HETE increases superoxide production and activates NAPDH oxidase in pulmonary artery endothelial cells.

  American journal of physiology. Lung cellular and molecular physiology 20080501

• Angiotensin II increases the expression of the transcription factor ETS-1 in mesangial cells.

  American journal of physiology. Renal physiology 20080501

• Mitochondrial dysfunction and redox signaling in atrial tachyarrhythmia.

  Experimental biology and medicine (Maywood, N.J.) 20080501

• H2O2 stimulation of the Cl-/HCO3- exchanger by angiotensin II and angiotensin II type 1 receptor distribution in membrane microdomains.

  Hypertension (Dallas, Tex. : 1979) 20080501

• Inorganic arsenic activates reduced NADPH oxidase in human primary macrophages through a Rho kinase/p38 kinase pathway.

  Journal of immunology (Baltimore, Md. : 1950) 20080501

• C-reactive protein inhibits endothelium-dependent nitric oxide-mediated dilation of retinal arterioles via enhanced superoxide production.

  Investigative ophthalmology & visual science 20080501

• Formyl-methionyl-leucyl-phenylalanine-induced dopaminergic neurotoxicity via microglial activation: a mediator between peripheral infection and neurodegeneration?

  Environmental health perspectives 20080501

• Inflammatory response in microvascular endothelium in sepsis: role of oxidants.

  Journal of clinical biochemistry and nutrition 20080501

• Induction of hypoxia-inducible factor 1alpha gene expression by vascular endothelial growth factor.

  The Journal of biological chemistry 20080425

• Transactivation of epidermal growth factor receptor in vascular and renal systems in rats with experimental hyperleptinemia: role in leptin-induced hypertension.

  Biochemical pharmacology 20080415

• Reactive oxygen species involved in prenylflavonoids, icariin and icaritin, initiating cardiac differentiation of mouse embryonic stem cells.

  Journal of cellular biochemistry 20080401

• Advanced oxidation protein products promote inflammation in diabetic kidney through activation of renal nicotinamide adenine dinucleotide phosphate oxidase.

  Endocrinology 20080401

• A reactive oxygen species-mediated component in neurogenic vasodilatation.

  Cardiovascular research 20080401

• Platelet factor 4/CXCL4-stimulated human monocytes induce apoptosis in endothelial cells by the release of oxygen radicals.

  Journal of leukocyte biology 20080401

• Local production of O2- by NAD(P)H oxidase in the sarcoplasmic reticulum of coronary arterial myocytes: cADPR-mediated Ca2+ regulation.

  Cellular signalling 20080401

• Reactive oxygen species participate in acute renal vasoconstrictor responses induced by ETA and ETB receptors.

  American journal of physiology. Renal physiology 20080401

• Role of 12/15-lipoxygenase in the expression of MCP-1 in mouse macrophages.

  American journal of physiology. Heart and circulatory physiology 20080401

• Oxidative stress and alpha1-adrenoceptor-mediated stimulation of the Cl-/HCO3- exchanger in immortalized SHR proximal tubular epithelial cells.

  British journal of pharmacology 20080401

• Activated NAD(P)H oxidase from supplemental oxygen induces neovascularization independent of VEGF in retinopathy of prematurity model.

  Investigative ophthalmology & visual science 20080401

• Age-related alterations in reactivity of cerebral arterioles: role of oxidative stress.

  Microcirculation (New York, N.Y. : 1994) 20080401

• STAT-1 signaling in human lung fibroblasts is induced by vanadium pentoxide through an IFN-beta autocrine loop.

  Journal of immunology (Baltimore, Md. : 1950) 20080315

• Protective effects of apocynin against cisplatin-induced oxidative stress and nephrotoxicity.

  Toxicology 20080312

• Role of NADPH oxidase and iNOS in vasoconstrictor responses of vessels from hypertensive and normotensive rats.

  British journal of pharmacology 20080301

• Aldosterone induces superoxide generation via Rac1 activation in endothelial cells.

  Endocrinology 20080301

• Regulation of proliferation of skeletal muscle precursor cells by NADPH oxidase.

  Antioxidants & redox signaling 20080301

• Oxidative stress and the genomic regulation of aldosterone-stimulated NHE1 activity in SHR renal proximal tubular cells.

  Molecular and cellular biochemistry 20080301

• NADPH oxidase activation: a mechanism of hypertension-associated erectile dysfunction.

  The journal of sexual medicine 20080301

• Oxidative stress in mononuclear cells plays a dominant role in their adhesion to mouse femoral artery after injury.

  Hypertension (Dallas, Tex. : 1979) 20080301

• NADPH oxidase and uncoupled nitric oxide synthase are major sources of reactive oxygen species in oral squamous cell carcinoma. Potential implications for immune regulation in high oxidative stress conditions.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20080301

• Molecular mechanisms of angiotensin II-mediated mitochondrial dysfunction: linking mitochondrial oxidative damage and vascular endothelial dysfunction.

  Circulation research 20080227

• Role of extracellular signal-regulated kinases (ERK) in leptin-induced hypertension.

  Life sciences 20080213

• Inhibition of NADPH oxidase prevents advanced glycation end product-mediated damage in diabetic nephropathy through a protein kinase C-alpha-dependent pathway.

  Diabetes 20080201

• Lymphocytic microparticles inhibit angiogenesis by stimulating oxidative stress and negatively regulating VEGF-induced pathways.

  American journal of physiology. Regulatory, integrative and comparative physiology 20080201

• In vivo reactive oxygen species production induced by ischemia in muscle arterioles of mice: involvement of xanthine oxidase and mitochondria.

  American journal of physiology. Heart and circulatory physiology 20080201

• Apocynin, NADPH oxidase, and vascular cells: a complex matter.

  Hypertension (Dallas, Tex. : 1979) 20080201

• Apocynin is not an inhibitor of vascular NADPH oxidases but an antioxidant.

  Hypertension (Dallas, Tex. : 1979) 20080201

• Glycated human serum albumin enhances macrophage inflammatory protein-1beta mRNA expression through protein kinase C-delta and NADPH oxidase in macrophage-like differentiated U937 cells.

  Biochimica et biophysica acta 20080201

• Protective effect of dietary potassium against vascular injury in salt-sensitive hypertension.

  Hypertension (Dallas, Tex. : 1979) 20080201

• Lipid rafts keep NADPH oxidase in the inactive state in human renal proximal tubule cells.

  Hypertension (Dallas, Tex. : 1979) 20080201

• Propofol restores brain microvascular function impaired by high glucose via the decrease in oxidative stress.

  Anesthesiology 20080201

• Revisiting oxidative damage in ALS: microglia, Nox, and mutant SOD1.

  The Journal of clinical investigation 20080201

• SOD1 mutations disrupt redox-sensitive Rac regulation of NADPH oxidase in a familial ALS model.

  The Journal of clinical investigation 20080201

• Aldosterone nongenomically produces NADPH oxidase-dependent reactive oxygen species and induces myocyte apoptosis.

  Hypertension research : official journal of the Japanese Society of Hypertension 20080201

• Inhibitory effect of simvastatin on the TNF-alpha- and angiotensin II-induced monocyte adhesion to endothelial cells is mediated through the suppression of geranylgeranyl isoprenoid-dependent ROS generation.

  Archives of pharmacal research 20080201

• Inhibition of NADPH oxidase by apocynin inhibits lipopolysaccharide (LPS) induced up-regulation of arginase in rat alveolar macrophages.

  European journal of pharmacology 20080128

• Dose formulation and analysis of diapocynin.

  Journal of agricultural and food chemistry 20080123

• Exercise and tachycardia increase NADPH oxidase and ryanodine receptor-2 activity: possible role in cardioprotection.

  Cardiovascular research 20080115

• Hemin upregulates Egr-1 expression in vascular smooth muscle cells via reactive oxygen species ERK-1/2-Elk-1 and NF-kappaB.

  Circulation research 20080104

• Peroxisome proliferator-activated receptor alpha agonists enhance cardiomyogenesis of mouse ES cells by utilization of a reactive oxygen species-dependent mechanism.

  Stem cells (Dayton, Ohio) 20080101

• Microglia induce neurotoxicity via intraneuronal Zn(2+) release and a K(+) current surge.

  Glia 20080101

• NADPH oxidase plays a crucial role in the activation of pancreatic stellate cells.

  American journal of physiology. Gastrointestinal and liver physiology 20080101

• Reactive oxygen species contribute to Ca2+ signals produced by osmotic stress in mouse skeletal muscle fibres.

  The Journal of physiology 20080101

• Regulation of swelling-activated Cl(-) current by angiotensin II signalling and NADPH oxidase in rabbit ventricle.

  Cardiovascular research 20080101

• Cognac polyphenolic compounds increase bradykinin-induced nitric oxide production in endothelial cells.

  Physiological research 20080101

• Healing potential of Picrorhiza kurroa (Scrofulariaceae) rhizomes against indomethacin-induced gastric ulceration: a mechanistic exploration.

  BMC complementary and alternative medicine 20080101

• MAO-B elevation in mouse brain astrocytes results in Parkinson's pathology.

  PloS one 20080101

• Acute inhibition of superoxide formation and Rac1 activation by nitric oxide and iloprost in human vascular smooth muscle cells in response to the thromboxane A2 analogue, U46619.

  Prostaglandins, leukotrienes, and essential fatty acids 20080101

• Uridine adenosine tetraphosphate induces contraction and relaxation in rat aorta.

  Vascular pharmacology 20080101

• Protein kinase C-mediated phosphorylation of p47 phox modulates platelet-derived growth factor-induced H2O2 generation and cell proliferation in human umbilical vein endothelial cells.

  Endothelium : journal of endothelial cell research 20080101

• Egr-1 regulates autophagy in cigarette smoke-induced chronic obstructive pulmonary disease.

  PloS one 20080101

• Apocynin: a potent NADPH oxidase inhibitor for the management of atrial fibrillation.

  Redox report : communications in free radical research 20080101

• Exercise training enhanced myocardial endothelial nitric oxide synthase (eNOS) function in diabetic Goto-Kakizaki (GK) rats.

  Cardiovascular diabetology 20080101

• Engineering and Applications of fungal laccases for organic synthesis.

  Microbial cell factories 20080101

• Neuroprotective effects of cannabidiol in endotoxin-induced uveitis: critical role of p38 MAPK activation.

  Molecular vision 20080101

• Apocynin: molecular aptitudes.

  Mediators of inflammation 20080101

• Botanical phenolics and brain health.

  Neuromolecular medicine 20080101

• Spinacia oleracea Modulates Radiation-Induced Biochemical Changes in Mice Testis.

  Indian journal of pharmaceutical sciences 20080101

• Possible involvement of 12-lipoxygenase activation in glucose-deprivation/reload-treated neurons.

  Neuroscience letters 20071218

• Ketamine-induced loss of phenotype of fast-spiking interneurons is mediated by NADPH-oxidase.

  Science (New York, N.Y.) 20071207

• Reactive oxygen species are messengers in maintenance of human and guinea pig gallbladder tonic contraction.

  American journal of physiology. Gastrointestinal and liver physiology 20071201

• Novel mechanism and role of angiotensin II induced vascular endothelial injury in hypertensive diastolic heart failure.

  Arteriosclerosis, thrombosis, and vascular biology 20071201

• Homocysteine stimulates NADPH oxidase-mediated superoxide production leading to endothelial dysfunction in rats.

  Canadian journal of physiology and pharmacology 20071201

• Reactive oxygen species generation by the ethylene-bis-dithiocarbamate (EBDC) fungicide mancozeb and its contribution to neuronal toxicity in mesencephalic cells.

  Neurotoxicology 20071101

• High glucose attenuates protein S-nitrosylation in endothelial cells: role of oxidative stress.

  Diabetes 20071101

• Reactive oxygen species (ROS) mediate the effects of leucine on translation regulation and type I collagen production in hepatic stellate cells.

  Biochimica et biophysica acta 20071101

• Small concentrations of oxLDL induce capillary tube formation from endothelial cells via LOX-1-dependent redox-sensitive pathway.

  Arteriosclerosis, thrombosis, and vascular biology 20071101

• Mitochondrial reactive oxygen species activate the slow force response to stretch in feline myocardium.

  The Journal of physiology 20071101

• Angiotensin II induces capillary formation from endothelial cells via the LOX-1 dependent redox-sensitive pathway.

  Hypertension (Dallas, Tex. : 1979) 20071101

• NADPH oxidase plays a central role in blood-brain barrier damage in experimental stroke.

  Stroke 20071101

• The polymorphonuclear leukocyte contributes to the development of hypertension in the Sabra rat.

  Journal of hypertension 20071101

• Aldosterone causes vasoconstriction in coronary arterioles of rats via angiotensin II type-1 receptor: influence of hypertension.

  European journal of pharmacology 20071031

• Fractionation of flax shives by water and aqueous ammonia treatment in a pressurized low-polarity water extractor.

  Journal of agricultural and food chemistry 20071017

• Mechanism of 6-hydroxydopamine neurotoxicity: the role of NADPH oxidase and microglial activation in 6-hydroxydopamine-induced degeneration of dopaminergic neurons.

  Journal of neurochemistry 20071001

• Role of NADPH oxidase and ANG II in diabetes-induced retinal leukostasis.

  American journal of physiology. Regulatory, integrative and comparative physiology 20071001

• Angiotensin II chronic infusion induces B1 receptor expression in aorta of rats.

  Hypertension (Dallas, Tex. : 1979) 20071001

• Reactive oxygen species and the regulation of renal Na+-K+-ATPase in opossum kidney cells.

  American journal of physiology. Regulatory, integrative and comparative physiology 20071001

• Rho-kinase as a novel gene therapeutic target in treatment of cold ischemia/reperfusion-induced acute lethal liver injury: effect on hepatocellular NADPH oxidase system.

  Gene therapy 20071001

• TNFalpha-initiated oxidative/nitrative stress mediates cardiomyocyte apoptosis in traumatic animals.

  Apoptosis : an international journal on programmed cell death 20071001

• Role of xanthine oxidoreductase in the reversal of diastolic heart failure by candesartan in the salt-sensitive hypertensive rat.

  Hypertension (Dallas, Tex. : 1979) 20071001

• Ethanol preconditioning protects against ischemia/reperfusion-induced brain damage: role of NADPH oxidase-derived ROS.

  Free radical biology & medicine 20071001

• Glycated human serum albumin induces interleukin 8 mRNA expression through reactive oxygen species and NADPH oxidase-dependent pathway in monocyte-derived U937 cells.

  Biological & pharmaceutical bulletin 20071001

• Mechanism of apoptosis induced by apigenin in HepG2 human hepatoma cells: involvement of reactive oxygen species generated by NADPH oxidase.

  Archives of pharmacal research 20071001

• Adverse balance of nitric oxide/peroxynitrite in the dysfunctional endothelium can be reversed by statins.

  Journal of cardiovascular pharmacology 20071001

• Selective loss of catecholaminergic wake active neurons in a murine sleep apnea model.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20070912

• Implication of cytosolic phospholipase A2 (cPLA2) in the regulation of human synoviocyte NADPH oxidase (Nox2) activity.

  Life sciences 20070908

• Administration of pigment epithelium-derived factor (PEDF) inhibits cold injury-induced brain edema in mice.

  Brain research 20070905

• NADPH oxidase mediates angiotensin II-induced endothelin-1 expression in vascular adventitial fibroblasts.

  Cardiovascular research 20070901

• Oxidative stress and increased eNOS and NADPH oxidase expression in mouse microvessel endothelial cells.

  Journal of cellular physiology 20070901

• Aging enhances pressure-induced arterial superoxide formation.

  American journal of physiology. Heart and circulatory physiology 20070901

• NOX5 is expressed at the plasma membrane and generates superoxide in response to protein kinase C activation.

  Biochimie 20070901

• Aldosterone induces epithelial-mesenchymal transition via ROS of mitochondrial origin.

  American journal of physiology. Renal physiology 20070901

• Tumor necrosis factor-alpha in mechanic trauma plasma mediates cardiomyocyte apoptosis.

  American journal of physiology. Heart and circulatory physiology 20070901

• Effects of apocynin and ethanol on intracerebral haemorrhage-induced brain injury in rats.

  Clinical and experimental pharmacology & physiology 20070901

• Sex differences in oxidative stress and the impact on blood pressure control and cardiovascular disease.

  Clinical and experimental pharmacology & physiology 20070901

• Adventitial application of the NADPH oxidase inhibitor apocynin in vivo reduces neointima formation and endothelial dysfunction in rabbits.

  Cardiovascular research 20070901

• Evidence against a role for NADPH oxidase modulating hepatic vascular tone in cirrhosis.

  Gastroenterology 20070901

• Simvastatin reverses target organ damage and oxidative stress in Angiotensin II hypertension: comparison with apocynin, tempol, and hydralazine.

  Journal of cardiovascular pharmacology 20070901

• Pharmacological inhibition of neuronal NADPH oxidase protects against 1-methyl-4-phenylpyridinium (MPP+)-induced oxidative stress and apoptosis in mesencephalic dopaminergic neuronal cells.

  Neurotoxicology 20070901

• Future therapeutic treatment of COPD: struggle between oxidants and cytokines.

  International journal of chronic obstructive pulmonary disease 20070901

• Polyunsaturated fatty acids modulate NOX 4 anion superoxide production in human fibroblasts.

  The Biochemical journal 20070815

• NOX4 activity is determined by mRNA levels and reveals a unique pattern of ROS generation.

  The Biochemical journal 20070815

• (-)-Epicatechin elevates nitric oxide in endothelial cells via inhibition of NADPH oxidase.

  Biochemical and biophysical research communications 20070803

• Reciprocal regulation of endothelial nitric-oxide synthase and NADPH oxidase by betulinic acid in human endothelial cells.

  The Journal of pharmacology and experimental therapeutics 20070801

• The reactivity of ortho-methoxy-substituted catechol radicals with sulfhydryl groups: contribution for the comprehension of the mechanism of inhibition of NADPH oxidase by apocynin.

  Biochemical pharmacology 20070801

• Polyphenols restore endothelial function in DOCA-salt hypertension: role of endothelin-1 and NADPH oxidase.

  Free radical biology & medicine 20070801

• Upregulation of glucose-6-phosphate dehydrogenase and NAD(P)H oxidase activity increases oxidative stress in failing human heart.

  Journal of cardiac failure 20070801

• Impairment of endothelium-dependent relaxation of rat aortas by homocysteine thiolactone and attenuation by captopril.

  Journal of cardiovascular pharmacology 20070801

• Antioxidative effects of azelnidipine on mesangial cell proliferation induced by highly concentrated insulin.

  European journal of pharmacology 20070719

• Activation of NADPH oxidase by transforming growth factor-beta in hepatocytes mediates up-regulation of epidermal growth factor receptor ligands through a nuclear factor-kappaB-dependent mechanism.

  The Biochemical journal 20070715

• Inhibition of NADPH oxidase reduces myocardial oxidative stress and apoptosis and improves cardiac function in heart failure after myocardial infarction.

  Free radical biology & medicine 20070715

• Diphenylene iodonium stimulates glucose uptake in skeletal muscle cells through mitochondrial complex I inhibition and activation of AMP-activated protein kinase.

  Cellular signalling 20070701

• Inhibition of the myosin light chain kinase prevents hypoxia-induced blood-brain barrier disruption.

  Journal of neurochemistry 20070701

• Oxidized low density lipoprotein receptor-1 mediates oxidized low density lipoprotein-induced apoptosis in human umbilical vein endothelial cells: role of reactive oxygen species.

  Vascular pharmacology 20070701

• Possible usefulness of apocynin, an NADPH oxidase inhibitor, for nitrate tolerance: prevention of NO donor-induced endothelial cell abnormalities.

  American journal of physiology. Heart and circulatory physiology 20070701

• Reactive oxygen species mediate a cellular 'memory' of high glucose stress signalling.

  Diabetologia 20070701

• Altering CO2 during reperfusion of ischemic cardiomyocytes modifies mitochondrial oxidant injury.

  Critical care medicine 20070701

• Cerebral vascular dysfunction during hypercholesterolemia.

  Stroke 20070701

• Angiotensin-(1-7) blocks the angiotensin II-stimulated superoxide production.

  Pharmacological research 20070701

• Staphylococcal enterotoxin C1-induced pyrogenic cytokine production in human peripheral blood mononuclear cells is mediated by NADPH oxidase and nuclear factor-kappa B.

  The FEBS journal 20070701

• The NAD(P)H oxidase inhibitor apocynin improves endothelial NO/superoxide balance and lowers effectively blood pressure in spontaneously hypertensive rats: comparison to calcium channel blockade.

  Clinical and experimental hypertension (New York, N.Y. : 1993) 20070701

• NADPH oxidase inhibitors: new antihypertensive agents?

  Journal of cardiovascular pharmacology 20070701

• Caveolin and MAP kinase interaction in angiotensin II preconditioning of the myocardium.

  Journal of cellular and molecular medicine 20070701

• Inhibition of apoptosis-regulated signaling kinase-1 and prevention of congestive heart failure by estrogen.

  Circulation 20070626

• 2,2',4,4'-Tetrachlorobiphenyl upregulates cyclooxygenase-2 in HL-60 cells via p38 mitogen-activated protein kinase and NF-kappaB.

  Toxicology and applied pharmacology 20070615

• Optimization of phenolic compounds analysis by capillary electrophoresis.

  Talanta 20070615

• Angiotensin II mediates postischemic leukocyte-endothelial interactions: role of calcitonin gene-related peptide.

  American journal of physiology. Heart and circulatory physiology 20070601

• Optimal reactive oxygen species concentration and p38 MAP kinase are required for coronary collateral growth.

  American journal of physiology. Heart and circulatory physiology 20070601

• Interleukin-10 counteracts impaired endothelium-dependent relaxation induced by ANG II in murine aortic rings.

  American journal of physiology. Heart and circulatory physiology 20070601

• Depolarization of the macula densa induces superoxide production via NAD(P)H oxidase.

  American journal of physiology. Renal physiology 20070601

• High glucose impairs early and late endothelial progenitor cells by modifying nitric oxide-related but not oxidative stress-mediated mechanisms.

  Diabetes 20070601

• Glutamate release from activated microglia requires the oxidative burst and lipid peroxidation.

  Journal of neurochemistry 20070601

• The uremic solute indoxyl sulfate induces oxidative stress in endothelial cells.

  Journal of thrombosis and haemostasis : JTH 20070601

• Effects of rosiglitazone on native low-density-lipoprotein-induced respiratory burst in circulating monocytes and on the leukocyte-endothelial interaction in cholesterol-fed rats.

  Naunyn-Schmiedeberg's archives of pharmacology 20070601

• NADPH oxidase- and mitochondrion-derived superoxide at rostral ventrolateral medulla in endotoxin-induced cardiovascular depression.

  Free radical biology & medicine 20070515

• Vascular NAD(P)H oxidase mediates endothelial dysfunction in basilar arteries from Otsuka Long-Evans Tokushima Fatty (OLETF) rats.

  Atherosclerosis 20070501

• The role of the renin-angiotensin system and oxidative stress in spontaneously hypertensive rat mesenteric collateral growth impairment.

  American journal of physiology. Heart and circulatory physiology 20070501

• Hypoosmotic swelling and ammonia increase oxidative stress by NADPH oxidase in cultured astrocytes and vital brain slices.

  Glia 20070501

• Apocynin alleviated hepatic oxidative burden and reduced liver injury in hypercholesterolaemia.

  Liver international : official journal of the International Association for the Study of the Liver 20070501

• Disruption of skeletal myocytes initiates superoxide release: contribution of NADPH oxidase.

  Shock (Augusta, Ga.) 20070501

• Transformation of polycyclic aromatic hydrocarbons by laccase is strongly enhanced by phenolic compounds present in soil.

  Environmental science & technology 20070415

• Hypoglycemic neuronal death is triggered by glucose reperfusion and activation of neuronal NADPH oxidase.

  The Journal of clinical investigation 20070402

• Angiotensin type-1-receptor antagonists reduce 6-hydroxydopamine toxicity for dopaminergic neurons.

  Neurobiology of aging 20070401

• NAD(P)H oxidase modulates angiogenesis and the development of portosystemic collaterals and splanchnic hyperaemia in portal hypertensive rats.

  Gut 20070401

• Role of oxidative stress in angiotensin II-induced enhanced expression of Gi(alpha) proteins and adenylyl cyclase signaling in A10 vascular smooth muscle cells.

  American journal of physiology. Heart and circulatory physiology 20070401

• Activation of vascular endothelial growth factor through reactive oxygen species mediates 20-hydroxyeicosatetraenoic acid-induced endothelial cell proliferation.

  The Journal of pharmacology and experimental therapeutics 20070401

• NADPH oxidase modulates myocardial Akt, ERK1/2 activation, and angiogenesis after hypoxia-reoxygenation.

  American journal of physiology. Heart and circulatory physiology 20070401

• Losartan reduces the increased participation of cyclooxygenase-2-derived products in vascular responses of hypertensive rats.

  The Journal of pharmacology and experimental therapeutics 20070401

• Anti-LOX-1 rescues endothelial function in coronary arterioles in atherosclerotic ApoE knockout mice.

  Arteriosclerosis, thrombosis, and vascular biology 20070401

• Inhibition of NAD(P)H oxidase reduces fibronectin expression in stroke-prone renovascular hypertensive rat brain.

  Clinical and experimental pharmacology & physiology 20070401

• Protein modification elicited by oxidized low-density lipoprotein (LDL) in endothelial cells: protection by (-)-epicatechin.

  Free radical biology & medicine 20070401

• Isolation and identification of potential cancer chemopreventive agents from methanolic extracts of green onion (Allium cepa).

  Phytochemistry 20070401

• Regulation of renal ouabain-resistant Na+-ATPase by leptin, nitric oxide, reactive oxygen species, and cyclic nucleotides: implications for obesity-associated hypertension.

  Clinical and experimental hypertension (New York, N.Y. : 1993) 20070401

• Glucose down-regulation of cGMP-dependent protein kinase I expression in vascular smooth muscle cells involves NAD(P)H oxidase-derived reactive oxygen species.

  Free radical biology & medicine 20070315

• NADPH oxidase inhibition improves neurological outcomes in surgically-induced brain injury.

  Neuroscience letters 20070313

• Flow increases superoxide production by NADPH oxidase via activation of Na-K-2Cl cotransport and mechanical stress in thick ascending limbs.

  American journal of physiology. Renal physiology 20070301

• Cyclooxygenase-1 is involved in endothelial dysfunction of mesenteric small arteries from angiotensin II-infused mice.

  Hypertension (Dallas, Tex. : 1979) 20070301

• Sildenafil inhibits the up-regulation of phosphodiesterase type 5 elicited with nicotine and tumour necrosis factor-alpha in cavernosal vascular smooth muscle cells: mediation by superoxide.

  BJU international 20070301

• Reactive oxygen species-dependent hypertension in dopamine D2 receptor-deficient mice.

  Hypertension (Dallas, Tex. : 1979) 20070301

• OKL38 is an oxidative stress response gene stimulated by oxidized phospholipids.

  Journal of lipid research 20070301

• Exercise training prevents arterial baroreflex dysfunction in rats treated with central angiotensin II.

  Hypertension (Dallas, Tex. : 1979) 20070301

• Stimulation of ES-cell-derived cardiomyogenesis and neonatal cardiac cell proliferation by reactive oxygen species and NADPH oxidase.

  Journal of cell science 20070301

• Bone-marrow derived hematopoietic stem/progenitor cells express multiple isoforms of NADPH oxidase and produce constitutively reactive oxygen species.

  Biochemical and biophysical research communications 20070223

• Impact of androgen-induced oxidative stress on hypertension in male SHR.

  American journal of physiology. Regulatory, integrative and comparative physiology 20070201

• Insulin-induced activation of hypoxia-inducible factor-1 requires generation of reactive oxygen species by NADPH oxidase.

  American journal of physiology. Heart and circulatory physiology 20070201

• Preconditioning protects endothelium by preventing ET-1-induced activation of NADPH oxidase and xanthine oxidase in post-ischemic heart.

  Journal of molecular and cellular cardiology 20070201

• Increased oxidative stress impairs endothelial modulation of contractions in arteries from spontaneously hypertensive rats.

  Journal of hypertension 20070201

• NADPH oxidase inhibition prevents cocaine-induced up-regulation of xanthine oxidoreductase and cardiac dysfunction.

  Journal of molecular and cellular cardiology 20070201

• Long-term effects of intrauterine malnutrition on vascular function in female offspring: implications of oxidative stress.

  Life sciences 20070130

• Diphenyleneiodonium induces ROS-independent p53 expression and apoptosis in human RPE cells.

  FEBS letters 20070123

• Hyperhomocysteinemia alters cardiac substrate metabolism by impairing nitric oxide bioavailability through oxidative stress.

  Circulation 20070116

• Tumor necrosis factor-alpha induces endothelial dysfunction in Lepr(db) mice.

  Circulation 20070116

• The oxidation of apocynin catalyzed by myeloperoxidase: proposal for NADPH oxidase inhibition.

  Archives of biochemistry and biophysics 20070115

• Endothelin-A and -B receptors, superoxide, and Ca2+ signaling in afferent arterioles.

  American journal of physiology. Renal physiology 20070101

• Low shear stress preferentially enhances IKK activity through selective sources of ROS for persistent activation of NF-kappaB in endothelial cells.

  American journal of physiology. Cell physiology 20070101

• Nicotine: the link between cigarette smoking and the progression of renal injury?

  American journal of physiology. Heart and circulatory physiology 20070101

• Superoxide mediates acute renal vasoconstriction produced by angiotensin II and catecholamines by a mechanism independent of nitric oxide.

  American journal of physiology. Heart and circulatory physiology 20070101

• Autocrine/paracrine pattern of superoxide production through NAD(P)H oxidase in coronary arterial myocytes.

  American journal of physiology. Heart and circulatory physiology 20070101

• Vascular lipotoxicity: endothelial dysfunction via fatty-acid-induced reactive oxygen species overproduction in obese Zucker diabetic fatty rats.

  Endocrinology 20070101

• Cigarette smoke-induced proinflammatory alterations in the endothelial phenotype: role of NAD(P)H oxidase activation.

  American journal of physiology. Heart and circulatory physiology 20070101

• A long-term 'memory' of HIF induction in response to chronic mild decreased oxygen after oxygen normalization.

  BMC cardiovascular disorders 20070101

• Mechanisms of H2O2-induced oxidative stress in endothelial cells exposed to physiologic shear stress.

  ASAIO journal (American Society for Artificial Internal Organs : 1992) 20070101

• Hydrophobic bile salts induce hepatocyte shrinkage via NADPH oxidase activation.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20070101

• AKL1, a botanical mixture for the treatment of asthma: a randomised, double-blind, placebo-controlled, cross-over study.

  BMC pulmonary medicine 20070101

• Effect of high-salt diet on vascular relaxation and oxidative stress in mesenteric resistance arteries.

  Journal of vascular research 20070101

• Inhibition of NAD(P)H oxidase reduces apoptosis and avascular retina in an animal model of retinopathy of prematurity.

  Molecular vision 20070101

• Apocynin attenuates cerebral infarction after transient focal ischaemia in rats.

  The Journal of international medical research 20070101

• The role of peroxisome proliferator-activated receptors in pulmonary vascular disease.

  PPAR research 20070101

• Inhibition of NAD(P)H oxidase attenuates aggregation of platelets from high-risk cardiac patients with aspirin resistance.

  Pharmacological reports : PR 20070101

• Platelet-derived exosomes from septic shock patients induce myocardial dysfunction.

  Critical care (London, England) 20070101

• Sustained stress response after oxidative stress in trabecular meshwork cells.

  Molecular vision 20070101

• Expression of isoforms of NADPH oxidase components in rat pancreatic islets.

  Life sciences 20061214

• Enhanced oxidative stress in kidneys of salt-sensitive hypertension: role of sensory nerves.

  American journal of physiology. Heart and circulatory physiology 20061201

• Essential role of C-Rel in nitric-oxide synthase-2 transcriptional activation: time-dependent control by salicylate.

  Molecular pharmacology 20061201

• Endotoxin induces toll-like receptor 4 expression in vascular smooth muscle cells via NADPH oxidase activation and mitogen-activated protein kinase signaling pathways.

  Arteriosclerosis, thrombosis, and vascular biology 20061201

• Hydrogen peroxide: a feed-forward dilator that couples myocardial metabolism to coronary blood flow.

  Arteriosclerosis, thrombosis, and vascular biology 20061201

• Beta-1, 3-glucan modulates PKC signalling in Lymnaea stagnalis defence cells: a role for PKC in H2O2 production and downstream ERK activation.

  The Journal of experimental biology 20061201

• Time-dependent transition from H(2)O(2)-extracellular signal-regulated kinase- to O(2)-nitric oxide-dependent mechanisms in the stimulatory effect of leptin on renal Na+/K+/-ATPase in the rat.

  Clinical and experimental pharmacology & physiology 20061201

• Role of reactive oxygen species in Kv channel inhibition and vasoconstriction induced by TP receptor activation in rat pulmonary arteries.

  Annals of the New York Academy of Sciences 20061201

• Angiotensin II-induced NADPH oxidase activation impairs insulin signaling in skeletal muscle cells.

  The Journal of biological chemistry 20061117

• High-fat diet-induced reduction in nitric oxide-dependent arteriolar dilation in rats: role of xanthine oxidase-derived superoxide anion.

  American journal of physiology. Heart and circulatory physiology 20061101

• Myotube depolarization generates reactive oxygen species through NAD(P)H oxidase; ROS-elicited Ca2+ stimulates ERK, CREB, early genes.

  Journal of cellular physiology 20061101

• Activation of nicotinamide adenine dinucleotide phosphate (reduced form) oxidase by advanced glycation end products links oxidative stress to altered retinal vascular endothelial growth factor expression.

  Metabolism: clinical and experimental 20061101

• Superoxide production and NADPH oxidase expression in human rheumatoid synovial cells: regulation by interleukin-1beta and tumour necrosis factor-alpha.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20061101

• European Academy of Paediatrics, Barcelona, Spain, October 7-10, 2006. Abstracts.

  European journal of pediatrics 20061101

• Insulin-induced vascular endothelial growth factor expression is mediated by the NADPH oxidase NOX3.

  Experimental cell research 20061015

• Apocynin normalizes hyperreactivity to phenylephrine in mesenteric arteries from cholesterol-fed mice by improving endothelium-derived hyperpolarizing factor response.

  Free radical biology & medicine 20061015

• Optimization of extraction of phenolic compounds from flax shives by pressurized low-polarity water.

  Journal of agricultural and food chemistry 20061004

• IL-1beta signaling in cat lower esophageal sphincter circular muscle.

  American journal of physiology. Gastrointestinal and liver physiology 20061001

• Angiopoietin-1-induced angiogenesis is modulated by endothelial NADPH oxidase.

  American journal of physiology. Heart and circulatory physiology 20061001

• Exaggerated vasomotor response to ANG II in rats with fetal programming of hypertension associated with exposure to a low-protein diet during gestation.

  American journal of physiology. Regulatory, integrative and comparative physiology 20061001

• Pathophysiological role of the acute inflammatory response during acetaminophen hepatotoxicity.

  Toxicology and applied pharmacology 20061001

• Simvastatin improves diabetes-induced coronary endothelial dysfunction.

  The Journal of pharmacology and experimental therapeutics 20061001

• 5-HT evokes sensory long-term facilitation of rodent carotid body via activation of NADPH oxidase.

  The Journal of physiology 20061001

• Enhancement of cardiac oxidative stress by tachycardia and its critical role in cardiac hypertrophy and fibrosis.

  Journal of hypertension 20061001

• Cytotoxicity of myeloperoxidase/nitrite-oxidized low-density lipoprotein toward endothelial cells is due to a high 7beta-hydroxycholesterol to 7-ketocholesterol ratio.

  Free radical biology & medicine 20061001

• Resveratrol attenuates TNF-alpha-induced activation of coronary arterial endothelial cells: role of NF-kappaB inhibition.

  American journal of physiology. Heart and circulatory physiology 20061001

• Modulation by homocysteine of the iberiotoxin-sensitive, Ca2+ -activated K+ channels of porcine coronary artery smooth muscle cells.

  European journal of pharmacology 20060928

• A transverse tubule NADPH oxidase activity stimulates calcium release from isolated triads via ryanodine receptor type 1 S -glutathionylation.

  The Journal of biological chemistry 20060908

• Nox2, Ca2+, and protein kinase C play a role in angiotensin II-induced free radical production in nucleus tractus solitarius.

  Hypertension (Dallas, Tex. : 1979) 20060901

• Increased reactive oxygen species contributes to kidney injury in mineralocorticoid hypertensive rats.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20060901

• Increased NADPH oxidase activity mediates spontaneous aortic tone in genetically hypertensive rats.

  European journal of pharmacology 20060821

• Reactive oxygen species mediate phorbol ester-stimulated cAMP response in human eosinophils.

  European journal of pharmacology 20060814

• Pollutant particles enhanced H2O2 production from NAD(P)H oxidase and mitochondria in human pulmonary artery endothelial cells.

  American journal of physiology. Cell physiology 20060801

• NADPH oxidase accounts for enhanced superoxide production and impaired endothelium-dependent smooth muscle relaxation in BKbeta1-/- mice.

  Arteriosclerosis, thrombosis, and vascular biology 20060801

• [Effect of NADPH oxidase on hypoxia-inducible factor-1alpha and endothelin-1 expression in human umbilical endothelial cells and its possible mechanism].

  Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20060801

• cAMP-response element-binding protein mediates acid-induced NADPH oxidase NOX5-S expression in Barrett esophageal adenocarcinoma cells.

  The Journal of biological chemistry 20060721

• Tumor necrosis factor-alpha induces endothelial dysfunction in the prediabetic metabolic syndrome.

  Circulation research 20060707

• Critical role of bradykinin-eNOS and oxidative stress-LOX-1 pathway in cardiovascular remodeling under chronic angiotensin-converting enzyme inhibition.

  Atherosclerosis 20060701

• Stretch-induced phosphorylation of focal adhesion kinase in endothelial cells: role of mitochondrial oxidants.

  American journal of physiology. Lung cellular and molecular physiology 20060701

• Serine 1179 phosphorylation of endothelial nitric oxide synthase caused by 2,4,6-trinitrotoluene through PI3K/Akt signaling in endothelial cells.

  Toxicology and applied pharmacology 20060701

• Increased RhoA/Rho-kinase signaling mediates spontaneous tone in aorta from angiotensin II-induced hypertensive rats.

  The Journal of pharmacology and experimental therapeutics 20060701

• Inhibition of ceramide-redox signaling pathway blocks glomerular injury in hyperhomocysteinemic rats.

  Kidney international 20060701

• Changes in vascular reactivity following administration of isoproterenol for 1 week: a role for endothelial modulation.

  British journal of pharmacology 20060701

• Salvianolic acid B from Salvia miltiorrhiza inhibits tumor necrosis factor-alpha (TNF-alpha)-induced MMP-2 upregulation in human aortic smooth muscle cells via suppression of NAD(P)H oxidase-derived reactive oxygen species.

  Journal of molecular and cellular cardiology 20060701

• An osteopontin-NADPH oxidase signaling cascade promotes pro-matrix metalloproteinase 9 activation in aortic mesenchymal cells.

  Circulation research 20060623

• Bone morphogenic protein-4 induces hypertension in mice: role of noggin, vascular NADPH oxidases, and impaired vasorelaxation.

  Circulation 20060620

• Isothermal titration calorimetry and 1H NMR studies on host-guest interaction of paeonol and two of its isomers with beta-cyclodextrin.

  International journal of pharmaceutics 20060619

• Mechanisms of H2O2-induced oxidative stress in endothelial cells.

  Free radical biology & medicine 20060615

• Ischemia induces nuclear NOX2 expression in cardiomyocytes and subsequently activates apoptosis.

  Apoptosis : an international journal on programmed cell death 20060601

• Cardiac contractile dysfunction in Lep/Lep obesity is accompanied by NADPH oxidase activation, oxidative modification of sarco(endo)plasmic reticulum Ca2+-ATPase and myosin heavy chain isozyme switch.

  Diabetologia 20060601

• Rosuvastatin treatment protects against nitrate-induced oxidative stress in eNOS knockout mice: implication of the NAD(P)H oxidase pathway.

  British journal of pharmacology 20060601

• Increased oxidative stress in lambs with increased pulmonary blood flow and pulmonary hypertension: role of NADPH oxidase and endothelial NO synthase.

  American journal of physiology. Lung cellular and molecular physiology 20060601

• Superoxide auto-augments superoxide formation and upregulates gp91(phox) expression in porcine pulmonary artery endothelial cells: inhibition by iloprost.

  European journal of pharmacology 20060524

• Apocynin protects against global cerebral ischemia-reperfusion-induced oxidative stress and injury in the gerbil hippocampus.

  Brain research 20060523

• The NADPH oxidase inhibitor apocynin (acetovanillone) induces oxidative stress.

  Toxicology and applied pharmacology 20060501

• Mitochondrial reactive oxygen species contribute to high NaCl-induced activation of the transcription factor TonEBP/OREBP.

  American journal of physiology. Renal physiology 20060501

• NAD(P)H oxidase contributes to the progression of remote hepatic parenchymal injury and endothelial dysfunction, but not microvascular perfusion deficits.

  American journal of physiology. Gastrointestinal and liver physiology 20060501

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• Notoginsenoside R1 inhibits TNF-alpha-induced fibronectin production in smooth muscle cells via the ROS/ERK pathway.

  Free radical biology & medicine 20060501

• Oxidant stress and blood pressure responses to angiotensin II administration in rats fed varying salt diets.

  American journal of hypertension 20060501

• NAD(P)H oxidase-stimulating activity of serum from type 2 diabetic patients with retinopathy mediates enhanced endothelial expression of E-selectin.

  Life sciences 20060425

• NAD(P)H oxidase in paraventricular nucleus contributes to the effect of angiotensin II on cardiac sympathetic afferent reflex.

  Brain research 20060412

• TNF-alpha dilates cerebral arteries via NAD(P)H oxidase-dependent Ca2+ spark activation.

  American journal of physiology. Cell physiology 20060401

• Microglia potentiate damage to blood-brain barrier constituents: improvement by minocycline in vivo and in vitro.

  Stroke 20060401

• NADPH oxidase in the renal medulla causes oxidative stress and contributes to salt-sensitive hypertension in Dahl S rats.

  Hypertension (Dallas, Tex. : 1979) 20060401

• Control of plasma glucose with alpha-glucosidase inhibitor attenuates oxidative stress and slows the progression of heart failure in mice.

  Cardiovascular research 20060401

• Angiotensin II-stimulated collagen production in cardiac fibroblasts is mediated by reactive oxygen species.

  Journal of hypertension 20060401

• Apocynin but not L-arginine prevents and reverses dexamethasone-induced hypertension in the rat.

  American journal of hypertension 20060401

• Dopamine promotes the survival of embryonic striatal cells: involvement of superoxide and endogenous NADPH oxidase.

  Neurochemical research 20060401

• Regulation of cardiotrophin-1 expression in mouse embryonic stem cells by HIF-1alpha and intracellular reactive oxygen species.

  Journal of cell science 20060315

• Glycated proteins stimulate reactive oxygen species production in cardiac myocytes: involvement of Nox2 (gp91phox)-containing NADPH oxidase.

  Circulation 20060307

• Superoxide anion is elevated in sympathetic neurons in DOCA-salt hypertension via activation of NADPH oxidase.

  American journal of physiology. Heart and circulatory physiology 20060301

• Characteristics and actions of NAD(P)H oxidase on the sarcoplasmic reticulum of coronary artery smooth muscle.

  American journal of physiology. Heart and circulatory physiology 20060301

• Expression of two temporally distinct microglia-related gene clusters after spinal cord injury.

  Glia 20060301

• Elevated concentrations of nonesterified fatty acids increase monocyte expression of CD11b and adhesion to endothelial cells.

  Arteriosclerosis, thrombosis, and vascular biology 20060301

• S-glutathiolation by peroxynitrite of p21ras at cysteine-118 mediates its direct activation and downstream signaling in endothelial cells.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060301

• Effect of apocynin treatment on renal expression of COX-2, NOS1, and renin in Wistar-Kyoto and spontaneously hypertensive rats.

  American journal of physiology. Regulatory, integrative and comparative physiology 20060301

• Oral administration of the NADPH-oxidase inhibitor apocynin partially restores diminished cartilage proteoglycan synthesis and reduces inflammation in mice.

  European journal of pharmacology 20060215

• Penicillamine administration reverses the inhibitory effect of hyperhomocysteinaemia on endothelium-dependent relaxation and superoxide formation in the aorta of the rabbit.

  European journal of pharmacology 20060215

• Inhibition of NADPH oxidase improves impaired reactivity of pial arterioles during chronic exposure to nicotine.

  Journal of applied physiology (Bethesda, Md. : 1985) 20060201

• Role of NAD(P)H oxidase in alcohol-induced impairment of endothelial nitric oxide synthase-dependent dilation of cerebral arterioles.

  Stroke 20060201

• Leptin regulates cardiomyocyte contractile function through endothelin-1 receptor-NADPH oxidase pathway.

  Hypertension (Dallas, Tex. : 1979) 20060201

• Reactive oxygen species mediate shear stress-induced fluid-phase endocytosis in vascular endothelial cells.

  Free radical research 20060201

• Alcohol-induced impairment of neuronal nitric oxide synthase (nNOS)-dependent dilation of cerebral arterioles: role of NAD(P)H oxidase.

  Journal of molecular and cellular cardiology 20060201

• Activation of JNK and xanthine oxidase by TNF-alpha impairs nitric oxide-mediated dilation of coronary arterioles.

  Journal of molecular and cellular cardiology 20060201

• Microglia proliferation is regulated by hydrogen peroxide from NADPH oxidase.

  Journal of immunology (Baltimore, Md. : 1950) 20060115

• NADPH oxidase is involved in angiotensin II-induced apoptosis in H9C2 cardiac muscle cells: effects of apocynin.

  Free radical biology & medicine 20060115

• Contribution of glibenclamide-sensitive, ATP-dependent K+ channel activation to acetophenone analogues-mediated in vitro pulmonary artery relaxation of rat.

  Life sciences 20060102

• Increased superoxide anion production by interleukin-1beta impairs nitric oxide-mediated relaxation in resistance arteries.

  The Journal of pharmacology and experimental therapeutics 20060101

• Low-density lipoprotein cholesterol determines oxidative stress and endothelial dysfunction in saphenous veins from patients with coronary artery disease.

  Arteriosclerosis, thrombosis, and vascular biology 20060101

• c-Jun N-terminal kinase inhibition and alpha-tocopherol protect midbrain dopaminergic neurons from interferon-gamma/lipopolysaccharide-induced injury without affecting nitric oxide production.

  Journal of neuroscience research 20060101

• Intricacies of brain angiotensin II signalling pathways.

  Journal of hypertension 20060101

• Acute pressor effect of central angiotensin II is mediated by NAD(P)H-oxidase-dependent production of superoxide in the hypothalamic cardiovascular regulatory nuclei.

  Journal of hypertension 20060101

• D5 dopamine receptor regulation of reactive oxygen species production, NADPH oxidase, and blood pressure.

  American journal of physiology. Regulatory, integrative and comparative physiology 20060101

• Angiotensin preconditioning of the heart: evidence for redox signaling.

  Cell biochemistry and biophysics 20060101

• Platelet regulation by NO/cGMP signaling and NAD(P)H oxidase-generated ROS.

  Blood cells, molecules & diseases 20060101

• Differential upregulation of Nox homologues of NADPH oxidase by tumor necrosis factor-alpha in human aortic smooth muscle and embryonic kidney cells.

  Journal of cellular and molecular medicine 20060101

• Estrogen-induced DNA synthesis in vascular endothelial cells is mediated by ROS signaling.

  BMC cardiovascular disorders 20060101

• Decreased morbidity following long saphenous vein harvesting using a minimally invasive technique: a randomised controlled trial comparing two techniques for long saphenous vein harvest.

  Journal of cardiothoracic surgery 20060101

• Folic acid inhibits homocysteine-induced superoxide anion production and nuclear factor kappa B activation in macrophages.

  Canadian journal of physiology and pharmacology 20060101

• Apocynin derivatives interrupt intracellular signaling resulting in decreased migration in breast cancer cells.

  Journal of biomedicine & biotechnology 20060101

• Fibrillar beta-amyloid peptide Abeta1-40 activates microglial proliferation via stimulating TNF-alpha release and H2O2 derived from NADPH oxidase: a cell culture study.

  Journal of neuroinflammation 20060101

• NADPH oxidases in the kidney.

  Antioxidants & redox signaling 20060101

• Inhibition of NAD(P)H oxidase alleviates impaired NOS-dependent responses of pial arterioles in type 1 diabetes mellitus.

  Microcirculation (New York, N.Y. : 1994) 20060101

• The microglial NADPH oxidase complex as a source of oxidative stress in Alzheimer's disease.

  Journal of neuroinflammation 20060101

• Arachidonate and NADPH oxidase synergise with iNOS to induce death in macrophages: mechanisms of inflammatory degeneration.

  Pharmacological reports : PR 20060101

• Nebivolol reduces nitroxidative stress and restores nitric oxide bioavailability in endothelium of black Americans.

  Circulation 20051213

• Endothelin mediates superoxide production and vasoconstriction through activation of NADPH oxidase and uncoupled nitric-oxide synthase in the rat aorta.

  The Journal of pharmacology and experimental therapeutics 20051201

• Tachycardia increases NADPH oxidase activity and RyR2 S-glutathionylation in ventricular muscle.

  Journal of molecular and cellular cardiology 20051201

• Oxidized-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine induces vascular endothelial superoxide production: implication of NADPH oxidase.

  Free radical biology & medicine 20051201

• Rac1-NADPH oxidase-regulated generation of reactive oxygen species mediates glutamate-induced apoptosis in SH-SY5Y human neuroblastoma cells.

  Free radical research 20051201

• Increased phagocytic nicotinamide adenine dinucleotide phosphate oxidase-dependent superoxide production in patients with early chronic kidney disease.

  Kidney international. Supplement 20051201

• Bile salt-induced apoptosis involves NADPH oxidase isoform activation.

  Gastroenterology 20051201

• Prevention and reversal by enalapril of target organ damage in angiotensin II hypertension.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20051201

• Coronary microvascular endothelial cell growth regulates expression of the gene encoding p22-phox.

  Free radical biology & medicine 20051115

• NADPH oxidase activity and function are profoundly greater in cerebral versus systemic arteries.

  Circulation research 20051111

• Enhanced oxidative stress impairs cAMP-mediated dilation by reducing Kv channel function in small coronary arteries of diabetic rats.

  American journal of physiology. Heart and circulatory physiology 20051101

• Angiotensin II, reactive oxygen species, and Ca2+ signaling in afferent arterioles.

  American journal of physiology. Renal physiology 20051101

• Activation of NAD(P)H oxidase by outward movements of H+ ions in renal medullary thick ascending limb of Henle.

  American journal of physiology. Renal physiology 20051101

• Endothelin-1 activation of JAK2 in vascular smooth muscle cells involves NAD(P)H oxidase-derived reactive oxygen species.

  Vascular pharmacology 20051101

• Cardioprotective mechanisms of spironolactone associated with the angiotensin-converting enzyme/epidermal growth factor receptor/extracellular signal-regulated kinases, NAD(P)H oxidase/lectin-like oxidized low-density lipoprotein receptor-1, and Rho-kinase pathways in aldosterone/salt-induced hypertensive rats.

  Hypertension research : official journal of the Japanese Society of Hypertension 20051101

• Platelet NAD(P)H-oxidase-generated ROS production regulates alphaIIbbeta3-integrin activation independent of the NO/cGMP pathway.

  Blood 20051015

• Alterations in redox homeostasis and prostaglandins impair endothelial-dependent vasodilation in euglycemic autoimmune nonobese diabetic mice.

  Free radical biology & medicine 20051015

• Expression and modulation of an NADPH oxidase in mammalian astrocytes.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20051005

• NADPH oxidase mediates hypersomnolence and brain oxidative injury in a murine model of sleep apnea.

  American journal of respiratory and critical care medicine 20051001

• Role of NADPH oxidase-mediated generation of reactive oxygen species in the mechanism of apoptosis induced by phenolic acids in HepG2 human hepatoma cells.

  Archives of pharmacal research 20051001

• Increased counteracting effect of eNOS and nNOS on an alpha1-adrenergic rise in total peripheral vascular resistance in spontaneous hypertensive rats.

  Cardiovascular research 20050901

• DFT studies, vibrational spectra and conformational stability of 4-hydroxy-3-methylacetophenone and 4-hydroxy-3-methoxyacetophenone.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20050901

• Aldosterone stimulates matrix metalloproteinases and reactive oxygen species in adult rat ventricular cardiomyocytes.

  Hypertension (Dallas, Tex. : 1979) 20050901

• Antioxidant treatment normalizes nitric oxide production, renal sodium handling and blood pressure in experimental hyperleptinemia.

  Life sciences 20050826

• Modulation of potassium currents by angiotensin and oxidative stress in cardiac cells from the diabetic rat.

  The Journal of physiology 20050815

• gp91phox-containing NAD(P)H oxidase mediates attenuation of nitric oxide-dependent control of myocardial oxygen consumption by ANG II.

  American journal of physiology. Heart and circulatory physiology 20050801

• Rapid increase in serum lipid peroxide 4-hydroxynonenal (HNE) through monocyte NADPH oxidase in early endo-toxemia.

  Free radical research 20050801

• Rosuvastatin treatment protects against nitrate-induced oxidative stress.

  Journal of cardiovascular pharmacology 20050801

• Inhibition of NAD(P)H oxidase activity blocks vascular endothelial growth factor overexpression and neovascularization during ischemic retinopathy.

  The American journal of pathology 20050801

• Involvement of NADPH oxidase isoforms and Src family kinases in CD95-dependent hepatocyte apoptosis.

  The Journal of biological chemistry 20050722

• Resveratrol and curcumin reduce the respiratory burst of Chlamydia-primed THP-1 cells.

  Biochemical and biophysical research communications 20050722

• Effect of sildenafil citrate and a nitric oxide donating sildenafil derivative, NCX 911, on cavernosal relaxation and superoxide formation in hypercholesterolaemic rabbits.

  European journal of pharmacology 20050711

• Mitochondrial respiratory chain and NAD(P)H oxidase are targets for the antiproliferative effect of carbon monoxide in human airway smooth muscle.

  The Journal of biological chemistry 20050708

• At least 2 distinct pathways generating reactive oxygen species mediate vascular cell adhesion molecule-1 induction by advanced glycation end products.

  Arteriosclerosis, thrombosis, and vascular biology 20050701

• Prednisolone augments superoxide formation in porcine pulmonary artery endothelial cells through differential effects on the expression of nitric oxide synthase and NADPH oxidase.

  British journal of pharmacology 20050701

• Supplementation with tetrahydrobiopterin prevents the cardiovascular effects of angiotensin II-induced oxidative and nitrosative stress.

  Journal of hypertension 20050701

• NADPH oxidase inhibitor, apocynin, restores the impaired endothelial-dependent and -independent responses and scavenges superoxide anion in rats with type 2 diabetes complicated by NO dysfunction.

  Diabetes, obesity & metabolism 20050701

• Apocynin but not allopurinol prevents and reverses adrenocorticotropic hormone-induced hypertension in the rat.

  American journal of hypertension 20050701

• [Phenolics from traditional Chinese medicine Sargentodoxa cuneata].

  Yao xue xue bao = Acta pharmaceutica Sinica 20050701

• Cytosolic NADH redox and thiol oxidation regulate pulmonary arterial force through ERK MAP kinase.

  American journal of physiology. Lung cellular and molecular physiology 20050601

• Endothelin-1 enhances oxidative stress, cell proliferation and reduces apoptosis in human umbilical vein endothelial cells: role of ETB receptor, NADPH oxidase and caveolin-1.

  British journal of pharmacology 20050601

• Metformin decreases intracellular production of reactive oxygen species in aortic endothelial cells.

  Metabolism: clinical and experimental 20050601

• High glucose-induced oxidative stress inhibits Na+/glucose cotransporter activity in renal proximal tubule cells.

  American journal of physiology. Renal physiology 20050501

• TGF-beta impairs renal autoregulation via generation of ROS.

  American journal of physiology. Renal physiology 20050501

• C-reactive protein inhibits endothelium-dependent NO-mediated dilation in coronary arterioles by activating p38 kinase and NAD(P)H oxidase.

  Arteriosclerosis, thrombosis, and vascular biology 20050501

• NF-kappaB activation plays a role in superoxide-mediated cerebral endothelial dysfunction after hypoxia/reoxygenation.

  Stroke 20050501

• Inhibition of NADPH oxidase attenuates vasospasm after experimental subarachnoid hemorrhage in rats.

  Stroke 20050501

• Role of NAD(P)H oxidase- and mitochondria-derived reactive oxygen species in cardioprotection of ischemic reperfusion injury by angiotensin II.

  Hypertension (Dallas, Tex. : 1979) 20050501

• Effects of NADPH oxidase inhibitor in diabetic nephropathy.

  Kidney international 20050501

• [Advanced oxidation protein products-induced tumor necrosis factor alpha secretion in monocytes via reactive oxygen species generation].

  Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20050501

• Cigarette smoke condensate induces MMP-12 gene expression in airway-like epithelia.

  Biochemical and biophysical research communications 20050429

• Hyperhomocysteinemia, a cardiac metabolic disease: role of nitric oxide and the p22phox subunit of NADPH oxidase.

  Circulation 20050426

• Nox 2 stimulates muscle differentiation via NF-kappaB/iNOS pathway.

  Free radical biology & medicine 20050415

• Pivotal role of gp91phox-containing NADH oxidase in lipopolysaccharide-induced tumor necrosis factor-alpha expression and myocardial depression.

  Circulation 20050405

• Activation of the JAK/STAT pathway in vascular smooth muscle by serotonin.

  American journal of physiology. Cell physiology 20050401

• Involvement of UVB-induced reactive oxygen species in TGF-beta biosynthesis and activation in keratinocytes.

  Free radical biology & medicine 20050401

• Angiotensin II-induced over-activation of p47phox in fibroblasts from hypertensives: which role in the enhanced ERK1/2 responsiveness to angiotensin II?

  Journal of hypertension 20050401

• Acute hypoxia simultaneously induces the expression of gp91phox and endothelial nitric oxide synthase in the porcine pulmonary artery.

  Thorax 20050401

• Biotransformation of benzaldehyde-type and acetophenone-type derivatives by Pharbitis nil hairy roots.

  Chemical & pharmaceutical bulletin 20050401

• Redox cycling of the herbicide paraquat in microglial cultures.

  Brain research. Molecular brain research 20050324

• Nitric oxide dynamics and endothelial dysfunction in type II model of genetic diabetes.

  European journal of pharmacology 20050321

• Apocynin inhibits NADPH oxidase in phagocytes but stimulates ROS production in non-phagocytic cells.

  Biochimica et biophysica acta 20050311

• Antioxidants inhibit human endothelial cell functions through down-regulation of endothelial nitric oxide synthase activity.

  European journal of pharmacology 20050307

• Role of reactive oxygen species in TGF-beta1-induced mitogen-activated protein kinase activation and epithelial-mesenchymal transition in renal tubular epithelial cells.

  Journal of the American Society of Nephrology : JASN 20050301

• Tumor promoter TPA stimulates MMP-9 secretion from human keratinocytes by activation of superoxide-producing NADPH oxidase.

  Free radical research 20050301

• Tyrosine kinase-mediated activation of NADPH oxidase enhances proliferative capacity of diabetic vascular smooth muscle cells.

  Life sciences 20050225

• A defect of neuronal nitric oxide synthase increases xanthine oxidase-derived superoxide anion and attenuates the control of myocardial oxygen consumption by nitric oxide derived from endothelial nitric oxide synthase.

  Circulation research 20050218

• Endostatin uncouples NO and Ca2+ response to bradykinin through enhanced O2*- production in the intact coronary endothelium.

  American journal of physiology. Heart and circulatory physiology 20050201

• c-Src and hydrogen peroxide mediate transforming growth factor-beta1-induced smooth muscle cell-gene expression in 10T1/2 cells.

  Arteriosclerosis, thrombosis, and vascular biology 20050201

• NADPH oxidase inhibition attenuates oxidative stress but not hypertension produced by chronic ET-1.

  Hypertension (Dallas, Tex. : 1979) 20050201

• The contribution of Nox4 to NADPH oxidase activity in mouse vascular smooth muscle.

  Cardiovascular research 20050201

• Impaired insulin-induced vasodilation in small coronary arteries of Zucker obese rats is mediated by reactive oxygen species.

  American journal of physiology. Heart and circulatory physiology 20050201

• Inhibitors of NADPH oxidase reduce the organ injury in hemorrhagic shock.

  Shock (Augusta, Ga.) 20050201

• Anti-oxidants reverse uraemia-induced down-regulation of mitochondrial membrane potential and interleukin-10 production.

  European journal of clinical investigation 20050201

• Hyperglycemia activates JAK2 signaling pathway in human failing myocytes via angiotensin II-mediated oxidative stress.

  Diabetes 20050201

• Atrial natriuretic peptide induces mitogen-activated protein kinase phosphatase-1 in human endothelial cells via Rac1 and NAD(P)H oxidase/Nox2-activation.

  Circulation research 20050107

• Cytosolic NADPH may regulate differences in basal Nox oxidase-derived superoxide generation in bovine coronary and pulmonary arteries.

  American journal of physiology. Heart and circulatory physiology 20050101

• Very long chain fatty acids activate NADPH oxidase in human dermal fibroblasts.

  Cell biochemistry and function 20050101

• The absence of reactive oxygen species production protects mice against bleomycin-induced pulmonary fibrosis.

  Respiratory research 20050101

• Possible involvement of NADPH oxidase and JNK in homocysteine-induced oxidative stress and apoptosis in human umbilical vein endothelial cells.

  Cardiovascular toxicology 20050101

• Effect of high glucose on superoxide in human mesangial cells: role of angiotensin II.

  Nephron. Experimental nephrology 20050101

• Antioxidant treatment normalizes renal Na+,K+-ATPase activity in leptin-treated rats.

  Pharmacological reports : PR 20050101

• Modeling human arthritic diseases in nonhuman primates.

  Arthritis research & therapy 20050101

• Removal of phenolic compounds in water by ultrafiltration membrane treatments.

  Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering 20050101

• Detection of reactive oxygen species in isolated, perfused lungs by electron spin resonance spectroscopy.

  Respiratory research 20050101

• Time-dependent effect of leptin on renal Na+,K+-ATPase activity.

  Acta biochimica Polonica 20050101

• Angiotensin II stimulates matrix metalloproteinase secretion in human vascular smooth muscle cells via nuclear factor-kappaB and activator protein 1 in a redox-sensitive manner.

  Journal of vascular research 20050101

• Mechanism and characteristics of stimuli-dependent ROS generation in undifferentiated HL-60 cells.

  Antioxidants & redox signaling 20050101

• Activation of microglial NADPH oxidase is synergistic with glial iNOS expression in inducing neuronal death: a dual-key mechanism of inflammatory neurodegeneration.

  Journal of neuroinflammation 20050101

• Oxidation of acetovanillone by photochemical processes and hydroxyl radicals.

  Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering 20050101

• Ultrafine carbon black particles stimulate proliferation of human airway epithelium via EGF receptor-mediated signaling pathway.

  American journal of physiology. Lung cellular and molecular physiology 20041201

• Evalution of oxidative stress in diabetic animals by in vivo electron spin resonance measurement--role of protein kinase C.

  Diabetes research and clinical practice 20041201

• [Advanced oxidation protein products induce reactive oxygen species production in endothelial cells].

  Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20041201

• Angiotensin II impairs neurovascular coupling in neocortex through NADPH oxidase-derived radicals.

  Circulation research 20041112

• Oxidant stress in kidneys of spontaneously hypertensive rats involves both oxidase overexpression and loss of extracellular superoxide dismutase.

  American journal of physiology. Renal physiology 20041101

• Association of increased phagocytic NADPH oxidase-dependent superoxide production with diminished nitric oxide generation in essential hypertension.

  Journal of hypertension 20041101

• Macrophage colony stimulatory factor and interferon-gamma trigger distinct mechanisms for augmentation of beta-amyloid-induced microglia-mediated neurotoxicity.

  Journal of neurochemistry 20041101

• Contribution of vascular NAD(P)H oxidase to endothelial dysfunction in heart failure and the therapeutic effects of HMG-CoA reductase inhibitor.

  Circulation journal : official journal of the Japanese Circulation Society 20041101

• Protective constituents against sepsis in mice from the root cortex of Paeonia suffruticosa.

  Archives of pharmacal research 20041101

• Superoxide mediates sympathoexcitation in heart failure: roles of angiotensin II and NAD(P)H oxidase.

  Circulation research 20041029

• Metabolism of gallic acid and catechin by Lactobacillus hilgardii from wine.

  Journal of agricultural and food chemistry 20041020

• Gene therapy of endothelial nitric oxide synthase and manganese superoxide dismutase restores delayed wound healing in type 1 diabetic mice.

  Circulation 20041019

• Acetylcholine-induced relaxation of rabbit basilar artery in vitro is rapidly reduced by reactive oxygen species in acute hyperglycemia: role of NADPH oxidase.

  Journal of cardiovascular pharmacology 20041001

• Combined effect of testosterone and apocynin on nitric oxide and superoxide production in PMA-differentiated THP-1 cells.

  Biochimica et biophysica acta 20040917

• Requirement for Rac1-dependent NADPH oxidase in the cardiovascular and dipsogenic actions of angiotensin II in the brain.

  Circulation research 20040903

• Mitochondrial requirement for endothelial responses to cyclic strain: implications for mechanotransduction.

  American journal of physiology. Lung cellular and molecular physiology 20040901

• Nitroaspirins and morpholinosydnonimine but not aspirin inhibit the formation of superoxide and the expression of gp91phox induced by endotoxin and cytokines in pig pulmonary artery vascular smooth muscle cells and endothelial cells.

  Circulation 20040831

• NADPH oxidase-dependent acid production in airway epithelial cells.

  The Journal of biological chemistry 20040827

• Cytotoxic mechanisms by M239V presenilin 2, a little-analyzed Alzheimer's disease-causative mutant.

  Journal of neuroscience research 20040815

• Cerebral vascular dysfunction mediated by superoxide in hyperhomocysteinemic mice.

  Stroke 20040801

• Functional role of NADPH oxidase in activation of platelets.

  Antioxidants & redox signaling 20040801

• Role of NADPH oxidase-mediated superoxide production in the regulation of E-selectin expression by endothelial cells subjected to anoxia/reoxygenation.

  Cardiovascular research 20040801

• Effect of NADPH oxidase inhibition on cardiopulmonary bypass-induced lung injury.

  American journal of physiology. Heart and circulatory physiology 20040801

• Apocynin prevents cyclooxygenase 2 expression in human monocytes through NADPH oxidase and glutathione redox-dependent mechanisms.

  Free radical biology & medicine 20040715

• Extracellular superoxide enhances 5-HT-induced murine pulmonary artery vasoconstriction.

  American journal of physiology. Lung cellular and molecular physiology 20040701

• Evidence for contribution of vascular NAD(P)H oxidase to increased oxidative stress in animal models of diabetes and obesity.

  Free radical biology & medicine 20040701

• Characterization of V642I-AbetaPP-induced cytotoxicity in primary neurons.

  Journal of neuroscience research 20040701

• Chronic high pressure-induced arterial oxidative stress: involvement of protein kinase C-dependent NAD(P)H oxidase and local renin-angiotensin system.

  The American journal of pathology 20040701

• Regulation of inducible nitric oxide synthase expression in advanced glycation end product-stimulated raw 264.7 cells: the role of heme oxygenase-1 and endogenous nitric oxide.

  Diabetes 20040701

• NADPH oxidase and cyclooxygenase mediate the ultraviolet B-induced generation of reactive oxygen species and activation of nuclear factor-kappaB in HaCaT human keratinocytes.

  Biochimie 20040701

• NADPH oxidase contributes to angiotensin II signaling in the nucleus tractus solitarius.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20040616

• The switch mechanism of the cell death mode from apoptosis to necrosis in menadione-treated human osteosarcoma cell line 143B cells.

  Microscopy research and technique 20040615

• Stable compounds of cigarette smoke induce endothelial superoxide anion production via NADPH oxidase activation.

  Arteriosclerosis, thrombosis, and vascular biology 20040601

• Race-specific differences in endothelial function: predisposition of African Americans to vascular diseases.

  Circulation 20040601

• Angiotensin II and endothelin-1 regulate MAP kinases through different redox-dependent mechanisms in human vascular smooth muscle cells.

  Journal of hypertension 20040601

• NADPH oxidase-mediated generation of reactive oxygen species is critically required for survival of undifferentiated human promyelocytic leukemia cell line HL-60.

  Free radical research 20040601

• Silvestrol and episilvestrol, potential anticancer rocaglate derivatives from Aglaia silvestris.

  The Journal of organic chemistry 20040514

• Azelnidipine, a newly developed long-acting calcium antagonist, inhibits tumor necrosis factor-alpha-induced interleukin-8 expression in endothelial cells through its anti-oxidative properties.

  Journal of cardiovascular pharmacology 20040501

• Insulin generates free radicals by an NAD(P)H, phosphatidylinositol 3'-kinase-dependent mechanism in human skin fibroblasts ex vivo.

  Diabetes 20040501

• Antioxidants inhibit angiogenesis in vivo through down-regulation of nitric oxide synthase expression and activity.

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• Reactive oxygen species amplify protein kinase C signaling in high glucose-induced fibronectin expression by human peritoneal mesothelial cells.

  Kidney international 20040401

• Involvement of NADPH oxidase-mediated generation of reactive oxygen species in the apototic cell death by capsaicin in HepG2 human hepatoma cells.

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• Endogenous adrenomedullin protects against vascular response to injury in mice.

  Circulation 20040309

• Role of the epidermal growth factor receptor in signaling strain-dependent activation of the brain natriuretic peptide gene.

  The Journal of biological chemistry 20040305

• Role of NAD(P)H oxidase on vascular alterations in angiotensin II-infused mice.

  Journal of hypertension 20040301

• Dietary compounds prevent oxidative damage and nitric oxide production by cells involved in demyelinating disease.

  Biochemical pharmacology 20040301

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  American journal of physiology. Heart and circulatory physiology 20040201

• Tempol lowers blood pressure and sympathetic nerve activity but not vascular O2- in DOCA-salt rats.

  Hypertension (Dallas, Tex. : 1979) 20040201

• Iloprost inhibits superoxide formation and gp91phox expression induced by the thromboxane A2 analogue U46619, 8-isoprostane F2alpha, prostaglandin F2alpha, cytokines and endotoxin in the pig pulmonary artery.

  British journal of pharmacology 20040201

• Amino- and carboxyl-terminal mutants of presenilin 1 cause neuronal cell death through distinct toxic mechanisms: Study of 27 different presenilin 1 mutants.

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• NAD(P)H oxidase inhibitor prevents blood pressure elevation and cardiovascular hypertrophy in aldosterone-infused rats.

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• Beta-amyloid peptides induce mitochondrial dysfunction and oxidative stress in astrocytes and death of neurons through activation of NADPH oxidase.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20040114

• Oxidant stress leads to impaired regulation of renal cortical oxygen consumption by nitric oxide in the aging kidney.

  Journal of the American Society of Nephrology : JASN 20040101

• Reactive oxygen species-sensitive p38 MAPK controls thrombin-induced migration of vascular smooth muscle cells.

  Journal of molecular and cellular cardiology 20040101

• Involvement of reactive oxygen species in bacterial killing within epithelial cells.

  International journal of immunopathology and pharmacology 20040101

• Glycated albumin induces superoxide generation in mesangial cells.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20040101

• Angiotensin II-mediated endothelial dysfunction: role of poly(ADP-ribose) polymerase activation.

  Molecular medicine (Cambridge, Mass.) 20040101

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  Prikladnaia biokhimiia i mikrobiologiia 20040101

• Nitric oxide -- superoxide cooperation in the regulation of renal Na(+),K(+)-ATPase.

  Acta biochimica Polonica 20040101

• A possible involvement of plasma membrane NAD(P)H oxidase in the switch mechanism of the cell death mode from apoptosis to necrosis in menadione-induced cell injury.

  Acta biochimica Polonica 20040101

• ROS production and Glut1 activity in two human megakaryocytic cell lines.

  BioFactors (Oxford, England) 20040101

• Coronary microvascular endothelial stunning after acute pressure overload in the conscious dog is caused by oxidant processes: the role of angiotensin II type 1 receptor and NAD(P)H oxidase.

  Circulation 20031209

• Role of xanthine oxidoreductase and NAD(P)H oxidase in endothelial superoxide production in response to oscillatory shear stress.

  American journal of physiology. Heart and circulatory physiology 20031201

• Role of superoxide in modulating the renal effects of angiotensin II.

  Hypertension (Dallas, Tex. : 1979) 20031201

• Superoxide does not mediate the acute vasoconstrictor effects of angiotensin II: a study in human and porcine arteries.

  Journal of hypertension 20031201

• Angiotensin II mediates LDL-induced superoxide generation in mesangial cells.

  American journal of physiology. Renal physiology 20031101

• Endothelin-1 stimulates arterial VCAM-1 expression via NADPH oxidase-derived superoxide in mineralocorticoid hypertension.

  Hypertension (Dallas, Tex. : 1979) 20031101

• Renal and vascular oxidative stress and salt-sensitivity of arterial pressure.

  Acta physiologica Scandinavica 20031101

• Platelets induce reactive oxygen species-dependent growth of human skin fibroblasts.

  European journal of cell biology 20031101

• Concomitant production of nitric oxide and superoxide in human macrophages.

  Biochemical and biophysical research communications 20031017

• Purification of bioethanol effluent in an UASB reactor system with simultaneous biogas formation.

  Biotechnology and bioengineering 20031005

• Simultaneous determination of 2-methoxyphenol, 2-methoxy-4-methylphenol, 2,6-dimethoxyphenol and 4'-hydroxy-3'-methoxyacetophenone in urine by capillary gas chromatography.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20031005

• Critical role of microglial NADPH oxidase-derived free radicals in the in vitro MPTP model of Parkinson's disease.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20031001

• Angiotensin II-NAD(P)H oxidase-stimulated superoxide modifies tubulovascular nitric oxide cross-talk in renal outer medulla.

  Hypertension (Dallas, Tex. : 1979) 20031001

• Mechanisms involved in the early increase of serotonin contraction evoked by endotoxin in rat middle cerebral arteries.

  British journal of pharmacology 20031001

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• High pressure induces superoxide production in isolated arteries via protein kinase C-dependent activation of NAD(P)H oxidase.

  Circulation 20030909

• Gene transfer of human guanosine 5'-triphosphate cyclohydrolase I restores vascular tetrahydrobiopterin level and endothelial function in low renin hypertension.

  Circulation 20030909

• NADPH oxidase-derived superoxide augments endothelin-1-induced venoconstriction in mineralocorticoid hypertension.

  Hypertension (Dallas, Tex. : 1979) 20030901

• NAD(P)H oxidase-generated superoxide anion accounts for reduced control of myocardial O2 consumption by NO in old Fischer 344 rats.

  American journal of physiology. Heart and circulatory physiology 20030901

• NADPH oxidase and enhanced superoxide generation in intrauterine undernourished rats: involvement of the renin-angiotensin system.

  Cardiovascular research 20030901

• Effect of the NAD(P)H oxidase inhibitor, apocynin, on peripheral nerve perfusion and function in diabetic rats.

  Life sciences 20030822

• High glucose augments the angiotensin II-induced activation of JAK2 in vascular smooth muscle cells via the polyol pathway.

  The Journal of biological chemistry 20030815

• AT1 blockade prevents glucose-induced cardiac dysfunction in ventricular myocytes: role of the AT1 receptor and NADPH oxidase.

  Hypertension (Dallas, Tex. : 1979) 20030801

• Critical role for microglial NADPH oxidase in rotenone-induced degeneration of dopaminergic neurons.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20030716

• Redox regulation of HIF-1alpha levels and HO-1 expression in renal medullary interstitial cells.

  American journal of physiology. Renal physiology 20030601

• Potential inhibitors from wet oxidation of wheat straw and their effect on ethanol production of Saccharomyces cerevisiae: wet oxidation and fermentation by yeast.

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• Increased superoxide production in coronary arteries in hyperhomocysteinemia: role of tumor necrosis factor-alpha, NAD(P)H oxidase, and inducible nitric oxide synthase.

  Arteriosclerosis, thrombosis, and vascular biology 20030301

• Vitamins reverse endothelial dysfunction through regulation of eNOS and NAD(P)H oxidase activities.

  Hypertension (Dallas, Tex. : 1979) 20030301

• Endothelin-1 increases vascular superoxide via endothelin(A)-NADPH oxidase pathway in low-renin hypertension.

  Circulation 20030225

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• Ceramide-induced activation of NADPH oxidase and endothelial dysfunction in small coronary arteries.

  American journal of physiology. Heart and circulatory physiology 20030201

• Late preconditioning by ethanol is initiated via an oxidant-dependent signaling pathway.

  Free radical biology & medicine 20030201

• Stretch enhances contraction of bovine coronary arteries via an NAD(P)H oxidase-mediated activation of the extracellular signal-regulated kinase mitogen-activated protein kinase cascade.

  Circulation research 20030110

• Science review: redox and oxygen-sensitive transcription factors in the regulation of oxidant-mediated lung injury: role for hypoxia-inducible factor-1alpha.

  Critical care (London, England) 20030101

• NAD(P)H oxidase inhibition improves endothelial function in rat and human blood vessels.

  Hypertension (Dallas, Tex. : 1979) 20021101

• Protective effects of apocynin on 'two-hit' injury induced by hemorrhagic shock and lipopolysaccharide.

  Acta pharmacologica Sinica 20021101

• Alpha-tocopherol decreases superoxide anion release in human monocytes under hyperglycemic conditions via inhibition of protein kinase C-alpha.

  Diabetes 20021001

• Proapoptotic and redox state-related signaling of reactive oxygen species generated by transformed fibroblasts.

  Oncogene 20020829

• Tumor necrosis factor-alpha increases airway smooth muscle oxidants production through a NADPH oxidase-like system to enhance myosin light chain phosphorylation and contractility.

  The Journal of biological chemistry 20020621

• Expression of a functionally active gp91phox-containing neutrophil-type NAD(P)H oxidase in smooth muscle cells from human resistance arteries: regulation by angiotensin II.

  Circulation research 20020614

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• Cytotoxic terpenoid and immunosuppressive phenolic glycosides from the root bark of Dictamnus dasycarpus.

  Planta medica 20020501

• Role of mitochondrial oxidant generation in endothelial cell responses to hypoxia.

  Arteriosclerosis, thrombosis, and vascular biology 20020401

• Molecular characterization of a superoxide-generating NAD(P)H oxidase in the ventilatory muscles.

  American journal of respiratory and critical care medicine 20020201

• Redox/ROS regulation of lipopolysaccharide-induced mitogen-activated protein kinase (MAPK) activation and MAPK-mediated TNF-alpha biosynthesis.

  British journal of pharmacology 20020101

• Recombinant human interleukin (IL)-1 beta-mediated regulation of hypoxia-inducible factor-1 alpha (HIF-1 alpha) stabilization, nuclear translocation and activation requires an antioxidant/reactive oxygen species (ROS)-sensitive mechanism.

  European cytokine network 20020101

• Inhibition of NADPH oxidase activation in endothelial cells by ortho-methoxy-substituted catechols.

  Endothelium : journal of endothelial cell research 20020101

• Effect of NADPH oxidase inhibition on E-selectin expression induced by concomitant anoxia/reoxygenation and TNF-alpha.

  Endothelium : journal of endothelial cell research 20020101

• Effects of methoxylation of apocynin and analogs on the inhibition of reactive oxygen species production by stimulated human neutrophils.

  European journal of pharmacology 20011221

• Role of reactive oxygen species in apoptosis induced by N-ethylmaleimide in HepG2 human hepatoblastoma cells.

  European journal of pharmacology 20011214

• Effect of apocynin on ozone-induced airway hyperresponsiveness to methacholine in asthmatics.

  Free radical biology & medicine 20011201

• Vitamin E alleviates renal injury, but not hypertension, during chronic nitric oxide synthase inhibition in rats.

  Journal of the American Society of Nephrology : JASN 20011201

• ET-1 stimulates pulmonary arterial smooth muscle cell proliferation via induction of reactive oxygen species.

  American journal of physiology. Lung cellular and molecular physiology 20011101

• NADH/NADPH oxidase and enhanced superoxide production in the mineralocorticoid hypertensive rat.

  Hypertension (Dallas, Tex. : 1979) 20011101

• Apocynin and 1400 W prevents airway hyperresponsiveness during allergic reactions in mice.

  British journal of pharmacology 20010901

• The effect of natural antioxidants, NAO and apocynin, on oxidative stress in the rat heart following LPS challenge.

  Toxicology letters 20010806

• HIV Tat activates c-Jun amino-terminal kinase through an oxidant-dependent mechanism.

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• Role of reactive oxygen species generated by NADPH oxidase in the mechanism of activation of K(+)-Cl(-)-cotransport by N-ethylmaleimide in HepG2 human hepatoma cells.

  Free radical research 20010701

• Surfactant protein D regulates NF-kappa B and matrix metalloproteinase production in alveolar macrophages via oxidant-sensitive pathways.

  Journal of immunology (Baltimore, Md. : 1950) 20010615

• Atrial natriuretic peptide inhibits tumor necrosis factor-alpha production by interferon-gamma-activated macrophages via suppression of p38 mitogen-activated protein kinase and nuclear factor-kappa B activation.

  Regulatory peptides 20010505

• Elevated superoxide production by active H-ras enhances human lung WI-38VA-13 cell proliferation, migration and resistance to TNF-alpha.

  Oncogene 20010322

• Phenyl propenoic side chain degradation of ferulic acid by Pycnoporus cinnabarinus - elucidation of metabolic pathways using [5-2H]-ferulic acid.

  Journal of biotechnology 20010223

• Superoxide excess in hypertension and aging: a common cause of endothelial dysfunction.

  Hypertension (Dallas, Tex. : 1979) 20010201

• Low-density lipoprotein induced actin cytoskeleton reorganization in endothelial cells: mechanisms of action.

  Endothelium : journal of endothelial cell research 20010101

• Reactive oxygen species regulate macrophage scavenger receptor type I, but not type II, in the human monocytic cell line THP-1.

  Molecular pharmacology 19980601

• Proliferation of airway epithelium after ozone exposure: effect of apocynin and dexamethasone.

  American journal of respiratory and critical care medicine 19980301

• Regulation of RANTES and ICAM-1 expression in murine mesangial cells.

  Journal of the American Society of Nephrology : JASN 19970401

• Axoplasm chemical composition in Myxicola and solubility properties of its structural proteins.

  The Journal of physiology 19751201