498-60-2 | 3-Furaldehyde

Packsize	Purity	Availability	Price	Discounted Price
250mg	98%	in stock	$8.00	$5.00
1g	98%	in stock	$12.00	$8.00
5g	98%	in stock	$33.00	$23.00
10g	98%	in stock	$65.00	$45.00
25g	98%	in stock	$158.00	$110.00

Description

• Catalog Number: AB65047
• Chemical Name: 3-Furaldehyde
• CAS Number: 498-60-2
• Molecular Formula: C5H4O2
• Molecular Weight: 96.0841
• MDL Number: MFCD00010424
• SMILES: O=Cc1cocc1

Computed Properties

• Complexity: 70.5
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 7
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• XLogP3: 0.5

Upstream Synthesis Route

Furan-3-carbaldehyde, also known as 3-formylfuran, is a versatile compound that finds common applications in chemical synthesis. Its unique structure, with a furan ring attached to an aldehyde functional group, allows for various chemical reactions and transformations. In organic synthesis, Furan-3-carbaldehyde serves as a key building block for the preparation of many important compounds.One essential application of Furan-3-carbaldehyde is as a precursor in the synthesis of heterocyclic compounds. By utilizing its aldehyde group, chemists can introduce Furan-3-carbaldehyde into multistep reactions to form complex ring structures, such as furan derivatives. These heterocyclic compounds have diverse functional groups and can exhibit a wide range of biological activities or serve as intermediates in the production of pharmaceuticals, agrochemicals, and materials.Another significant use of Furan-3-carbaldehyde is in the construction of natural product analogs. Chemists can modify the furan ring system or functional groups of Furan-3-carbaldehyde to mimic natural products with important biological properties. These analogs often possess enhanced stability, improved bioavailability, or altered activity compared to their natural counterparts, making them valuable tools for drug discovery and development.Overall, the application of Furan-3-carbaldehyde in chemical synthesis demonstrates its importance as a valuable building block for the preparation of diverse molecules with potential pharmaceutical, agricultural, or material applications.

Literature

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  The Journal of organic chemistry 20110603

• Neonicotinoid insecticides: oxidative stress in planta and metallo-oxidase inhibition.

  Journal of agricultural and food chemistry 20110511

• Photoisomerization and photochemistry of matrix-isolated 3-furaldehyde.

  The journal of physical chemistry. A 20101202

• Adsorption and separation of reactive aromatic isomers and generation and stabilization of their radicals within cadmium(II)-triazole metal-organic confined space in a single-crystal-to-single-crystal fashion.

  Journal of the American Chemical Society 20100526

• A direct RP-HPLC method for the determination of furanic aldehydes and acids in honey.

  Talanta 20090415

• Total synthesis of 20-norsalvinorin A. 1. Preparation of a key intermediate.

  The Journal of organic chemistry 20090320

• Synthesis of heteroaryl imines: theoretical and experimental approach to the determination of the configuration of C=N double bond.

  The Journal of organic chemistry 20060915

• Synthesis of new lipophilic ipomeanol analogues and their cytotoxic activities.

  Archiv der Pharmazie 20050101

• [Studies on the chemical constituents of the volatiles of Clerodendron bungei].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20040201

• Synthesis of (+)-manoalide via a copper(I)-mediated 1,2-metalate rearrangement.

  The Journal of organic chemistry 20030516