4985-46-0 | (2S)-2-amino-3-(4-hydroxyphenyl)propanamide

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$34.00	$24.00
5g	98%	in stock	$74.00	$52.00
25g	98%	in stock	$267.00	$187.00
100g	98%	in stock	$760.00	$532.00

Description

• Catalog Number: AB46395
• Chemical Name: (2S)-2-amino-3-(4-hydroxyphenyl)propanamide
• CAS Number: 4985-46-0
• Molecular Formula: C9H12N2O2
• Molecular Weight: 180.2038
• MDL Number: MFCD00069935
• SMILES: N[C@H](C(=O)N)Cc1ccc(cc1)O

Computed Properties

• Complexity: 177
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 13
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 3
• XLogP3: -0.6

Literature

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  Analytical chemistry 20120619

• Design of novel tyrosine-nitrogen mustard hybrid molecules active against uterine, ovarian and breast cancer cell lines.

  Steroids 20120401

• Fluorescence polarization biosensor based on an aptamer enzymatic cleavage protection strategy.

  Analytical and bioanalytical chemistry 20111201

• Optimization of the structure-switching aptamer-based fluorescence polarization assay for the sensitive tyrosinamide sensing.

  Analytica chimica acta 20111130

• Aptamer enzymatic cleavage protection assay for the gold nanoparticle-based colorimetric sensing of small molecules.

  Analytica chimica acta 20111114

• Glycan labeling strategies and their use in identification and quantification.

  Analytical and bioanalytical chemistry 20100801

• Inhibition of Ser/Thr phosphatases induces capacitation-associated signaling in the presence of Src kinase inhibitors.

  The Journal of biological chemistry 20100312

• Design strategies of fluorescent biosensors based on biological macromolecular receptors.

  Sensors (Basel, Switzerland) 20100101

• Noncompetitive fluorescence polarization aptamer-based assay for small molecule detection.

  Analytical chemistry 20090901

• Simultaneous delivery of doxorubicin and gemcitabine to tumors in vivo using prototypic polymeric drug carriers.

  Biomaterials 20090701

• Identification of tyrosine 806 as a molecular determinant of RET kinase sensitivity to ZD6474.

  Endocrine-related cancer 20090301

• Synthesis, spectroscopic and structural elucidation of tyrosinamide hydrogensquarate monohydrate.

  Amino acids 20090201

• Electropolymerized tyrosine-based thin films: selective cell binding via peptide recognition to novel electropolymerized biomimetic tyrosine RGDY films.

  Analytical biochemistry 20090101

• Image-guided and passively tumour-targeted polymeric nanomedicines for radiochemotherapy.

  British journal of cancer 20080916

• Microcalorimetrics studies of the thermodynamics and binding mechanism between L-tyrosinamide and aptamer.

  The journal of physical chemistry. B 20080529

• Physiological variations of stem cell factor and stromal-derived factor-1 in murine models of liver injury and regeneration.

  Liver international : official journal of the International Association for the Study of the Liver 20080301

• CE with electrochemical detection for investigation of label-free recognition of amino acid amides by guanine-rich DNA aptamers.

  Electrophoresis 20070801

• Antineoplastic agents. 515. Synthesis of human cancer cell growth inhibitors derived from 3,4-methylenedioxy-5,4'-dimethoxy-3'-amino-Z-stilbene.

  Journal of natural products 20050801

• NF-kappaB pathway protects cochlear hair cells from aminoglycoside-induced ototoxicity.

  Journal of neuroscience research 20050301

• Influence of alkyl group on amide nitrogen atom on fluorescence quenching of tyrosine amide and N-acetyltyrosine amide.

  Biophysical chemistry 20041001

• Immobilized DNA aptamers as target-specific chiral stationary phases for resolution of nucleoside and amino acid derivative enantiomers.

  Analytical chemistry 20040215

• Enzymatic copolymerization alters the structure of unpolymerized mixtures of the biomimetic monomers: the amphiphilic decyl ester of L-tyrosine and L-tyrosineamide--an AFM investigation of nano- to micrometer-scale structure differences.

  Biomacromolecules 20040101

• Chemolabile cellular microarrays for screening small molecules and peptides.

  Molecular diversity 20040101

• Antineoplastic agents. 487. Synthesis and biological evaluation of the antineoplastic agent 3,4-methylenedioxy-5,4'-dimethoxy-3'-amino-Z-stilbene and derived amino acid amides.

  Journal of medicinal chemistry 20030213

• Probing the binding specificity of C-type lectins in vivo.

  Methods in enzymology 20030101

• Spectroscopic properties of tyrosyl radicals in dipeptides.

  Journal of the American Chemical Society 20020515

• In vitro selection of DNA aptamers that bind L-tyrosinamide.

  Bioorganic & medicinal chemistry 20011001