504-24-5 | 4-Aminopyridine

Packsize	Purity	Availability	Price	Discounted Price
10g	99%	in stock	$23.00	$16.00
25g	99%	in stock	$34.00	$24.00
100g	99%	in stock	$101.00	$71.00

Description

• Catalog Number: AB51742
• Chemical Name: 4-Aminopyridine
• CAS Number: 504-24-5
• Molecular Formula: C5H6N2
• Molecular Weight: 94.1145
• MDL Number: MFCD00006439
• SMILES: Nc1ccncc1

Computed Properties

• Complexity: 48
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 7
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 1
• XLogP3: 0.3

Literature

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• 4-Amino-pyridinium cis-2-carb-oxy-cyclo-hexane-1-carboxyl-ate.

  Acta crystallographica. Section E, Structure reports online 20111001

• Significant effects of 4-aminopyridine and tetraethylammonium in the treatment of 6-hydroxydopamine-induced Parkinson's disease.

  Behavioural brain research 20110930

• DNA-linked nanoparticle building blocks for programmable matter.

  Angewandte Chemie (International ed. in English) 20110919

• jShaw1, a low-threshold, fast-activating K(v)3 from the hydrozoan jellyfish Polyorchis penicillatus.

  The Journal of experimental biology 20110915

• Preictal and ictal neurovascular and metabolic coupling surrounding a seizure focus.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20110914

• Role of perivascular adipose tissue-derived methyl palmitate in vascular tone regulation and pathogenesis of hypertension.

  Circulation 20110906

• 4-Aminopyridine improves gait variability in cerebellar ataxia due to CACNA 1A mutation.

  Journal of neurology 20110901

• On the mode of action of emodepside: slow effects on membrane potential and voltage-activated currents in Ascaris suum.

  British journal of pharmacology 20110901

• Role of inducible nitric oxide synthase in the pathogenesis of experimental leptospirosis.

  Microbial pathogenesis 20110901

• Regional differences in the effects of isoflurane on neurotransmitter release.

  Neuropharmacology 20110901

• Orthogonal wave propagation of epileptiform activity in the planar mouse hippocampus in vitro.

  Epilepsia 20110901

• Role of calcium-activated potassium channels in the genesis of 3,4-diaminopyridine-induced periodic contractions in isolated canine coronary artery smooth muscles.

  The Journal of pharmacology and experimental therapeutics 20110901

• Adult human heart slices are a multicellular system suitable for electrophysiological and pharmacological studies.

  Journal of molecular and cellular cardiology 20110901

• The role of regularity and synchrony of cerebellar Purkinje cells for pathological nystagmus.

  Annals of the New York Academy of Sciences 20110901

• Autoimmune channelopathies of the nervous system.

  Current neuropharmacology 20110901

• The pore structure and gating mechanism of K2P channels.

  The EMBO journal 20110831

• Compensatory network alterations upon onset of epilepsy in synapsin triple knock-out mice.

  Neuroscience 20110825

• Participation of the GABAergic system on the glutamate release of frontal cortex synaptosomes from Wistar rats with experimental autoimmune encephalomyelitis.

  Neuroscience 20110825

• Pioglitazone, a peroxisome proliferator-activated receptor-γ agonist, induces dilation of isolated porcine retinal arterioles: role of nitric oxide and potassium channels.

  Investigative ophthalmology & visual science 20110824

• Curcumin inhibits glutamate release in nerve terminals from rat prefrontal cortex: possible relevance to its antidepressant mechanism.

  Progress in neuro-psychopharmacology & biological psychiatry 20110815

• Luteolin inhibits the release of glutamate in rat cerebrocortical nerve terminals.

  Journal of agricultural and food chemistry 20110810

• Chemical cell-surface receptor engineering using affinity-guided, multivalent organocatalysts.

  Journal of the American Chemical Society 20110810

• Suppression of a neocortical potassium channel activity by intracellular amyloid-β and its rescue with Homer1a.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20110803

• Single-pixel optical fluctuation analysis of calcium channel function in active zones of motor nerve terminals.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20110803

• Arrangement of subunits in functional NMDA receptors.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20110803

• Two distinct Ca(2+) signaling pathways modulate sperm flagellar beating patterns in mice.

  Biology of reproduction 20110801

• A bistable computational model of recurring epileptiform activity as observed in rodent slice preparations.

  Neural networks : the official journal of the International Neural Network Society 20110801

• Role of myosin light chain kinase in cardiotrophin-1-induced cardiac myofibroblast cell migration.

  American journal of physiology. Heart and circulatory physiology 20110801

• A randomized trial of 4-aminopyridine in EA2 and related familial episodic ataxias.

  Neurology 20110719

• Activation of κ opioid receptors increases intrinsic excitability of dentate gyrus granule cells.

  The Journal of physiology 20110715

• Severe accidental overdose of 4-aminopyridine due to a compounding pharmacy error.

  The Journal of emergency medicine 20110701

• Pharmacotherapy of vestibular and ocular motor disorders, including nystagmus.

  Journal of neurology 20110701

• A-type K+ current dominates somatic excitability of delayed firing neurons in rat substantia gelatinosa.

  Synapse (New York, N.Y.) 20110701

• Contractile and electrophysiological properties of pulmonary artery smooth muscle are not altered in TASK-1 knockout mice.

  The Journal of physiology 20110701

• Idebenone inhibition of glutamate release from rat cerebral cortex nerve endings by suppression of voltage-dependent calcium influx and protein kinase A.

  Naunyn-Schmiedeberg's archives of pharmacology 20110701

• Dalfampridine: a brief review of its mechanism of action and efficacy as a treatment to improve walking in patients with multiple sclerosis.

  Current medical research and opinion 20110701

• Testosterone relaxes human internal spermatic vein through potassium channel opening action.

  Urology 20110701

• Kynurenic acid synthesis and kynurenine aminotransferases expression in colon derived normal and cancer cells.

  Scandinavian journal of gastroenterology 20110701

• Treatment of walking impairment in multiple sclerosis: an unmet need for a disease-specific disability.

  Expert opinion on pharmacotherapy 20110701

• The 4-aminopyridine in vitro epilepsy model analyzed with a perforated multi-electrode array.

  Neuropharmacology 20110601

• Perivascular adipose tissue and its role in type 2 diabetes and cardiovascular disease.

  Current diabetes reports 20110601

• Dichotomous cellular properties of mouse orexin/hypocretin neurons.

  The Journal of physiology 20110601

• Adenosine triphosphate-sensitive potassium channel blockers attenuate the antiallodynic effect of R-PIA in neuropathic rats.

  Anesthesia and analgesia 20110601

• Role of calcium and potassium channels in effects of hydrogen sulfide on frog myocardial contractility.

  Bulletin of experimental biology and medicine 20110601

• Control of programmed cell death by distinct electrical activity patterns.

  Cerebral cortex (New York, N.Y. : 1991) 20110501

• Baclofen and adenosine inhibition of synaptic transmission at CA3-CA1 synapses display differential sensitivity to K+ channel blockade.

  Cellular and molecular neurobiology 20110501

• Pharmacology of currents underlying the different firing patterns of spinal sensory neurons and interneurons identified in vivo using multivariate analysis.

  Journal of neurophysiology 20110501

• Acrolein induces myelin damage in mammalian spinal cord.

  Journal of neurochemistry 20110501

• A-type K+ currents in intralaminar thalamocortical relay neurons.

  Pflugers Archiv : European journal of physiology 20110501

• A new approach for generic screening and quantitation of potential genotoxic alkylation compounds by pre-column derivatization and LC-MS/MS analysis.

  Analytical and bioanalytical chemistry 20110501

• Guidelines and best practices for appropriate use of dalfampridine in managed care populations.

  The American journal of managed care 20110501

• Synthesis of 3-aryl-2-arylamidobenzofurans based on the Curtius rearrangement.

  The Journal of organic chemistry 20110415

• Regioselective cobalt-catalyzed formation of bicyclic 3- and 4-aminopyridines.

  Organic letters 20110415

• Voltage-gated K+ channels play a role in cAMP-stimulated neuritogenesis in mouse neuroblastoma N2A cells.

  Journal of cellular physiology 20110401

• Effect of 4-aminopyridine on gravity dependence and neural integrator function in patients with idiopathic downbeat nystagmus.

  Journal of neurology 20110401

• Impaired spare respiratory capacity in cortical synaptosomes from Sod2 null mice.

  Free radical biology & medicine 20110401

• Transcriptional activation of the anchoring protein SAP97 by heat shock factor (HSF)-1 stabilizes K(v) 1.5 channels in HL-1 cells.

  British journal of pharmacology 20110401

• Is connexin36 critical for GABAergic hypersynchronization in the hippocampus?

  The Journal of physiology 20110401

• Pulsed magnetic fields enhance the rate of recovery of damaged nerve excitability.

  Bioelectromagnetics 20110401

• Electrophysiological, pharmacological and molecular profile of the transient outward rectifying conductance in rat sympathetic preganglionic neurons in vitro.

  Neuroscience 20110331

• Inhibition of glutamate release by bupropion in rat cerebral cortex nerve terminals.

  Progress in neuro-psychopharmacology & biological psychiatry 20110330

• Electrochemiluminescent metallopolymer-nanoparticle composites: nanoparticle size effects.

  Analytical chemistry 20110315

• Errors in the measurement of voltage-activated ion channels in cell-attached patch-clamp recordings.

  Nature communications 20110315

• Effect of potassium channel opener pinacidil on the contractions elicited electrically or by noradrenaline in the human radial artery.

  European journal of pharmacology 20110311

• Properties of deactivation gating currents in Shaker channels.

  Biophysical journal 20110302

• Targeting atrioventricular differences in ion channel properties for terminating acute atrial fibrillation in pigs.

  Cardiovascular research 20110301

• Pharmacological evidence that Ca²+ channels and, to a lesser extent, K+ channels mediate the relaxation of testosterone in the canine basilar artery.

  Steroids 20110301

• Distance- and activity-dependent modulation of spike back-propagation in layer V pyramidal neurons of the medial entorhinal cortex.

  Journal of neurophysiology 20110301

• The stretch-dependent potassium channel TREK-1 and its function in murine myometrium.

  The Journal of physiology 20110301

• Presynaptic action potential waveform determines cortical synaptic latency.

  The Journal of physiology 20110301

• L-Type calcium channel blockade reduces network activity in human epileptic hypothalamic hamartoma tissue.

  Epilepsia 20110301

• Effects of 3-4 diaminopyridine (DAP) in motor neuron diseases.

  Journal of clinical neuromuscular disease 20110301

• Vasodilatory effect of hydroxyethyl methacrylate and triethylene glycol dimethacrylate in rat aorta through calcium antagonistic action.

  Journal of endodontics 20110301

• 4-aminopyridinium 2-(anthracen-9-yl)-3-oxo-3H-inden-1-olate monohydrate.

  Acta crystallographica. Section C, Crystal structure communications 20110301

• Protein kinase inhibitor as a potential candidate for epilepsy treatment.

  Epilepsia 20110301

• RNA editing of Kv1.1 channels may account for reduced ictogenic potential of 4-aminopyridine in chronic epileptic rats.

  Epilepsia 20110301

• Membrane potential-dependent modulation of recurrent inhibition in rat neocortex.

  PLoS biology 20110301

• Depressogenic effects of medications: a review.

  Dialogues in clinical neuroscience 20110301

• [Design, synthesis and antiepileptic activity of 4-(2-acetoxybenzoylamino) butyrate derivatives].

  Yao xue xue bao = Acta pharmaceutica Sinica 20110301

• Treatment of walking impairment in multiple sclerosis with dalfampridine.

  Therapeutic advances in neurological disorders 20110301

• Dual function of Zn2+ on the intrinsic excitability of dopaminergic neurons in rat substantia nigra.

  Neuroscience 20110223

• Functional nicotinic acetylcholine receptors containing α6 subunits are on GABAergic neuronal boutons adherent to ventral tegmental area dopamine neurons.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20110216

• Treatment for Lambert-Eaton myasthenic syndrome.

  The Cochrane database of systematic reviews 20110216

• Activity-dependent regulation of surface glucose transporter-3.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20110209

• Effects of acetazolamide on transient K+ currents and action potentials in nodose ganglion neurons of adult rats.

  CNS neuroscience & therapeutics 20110201

• Different expression of large-conductance calcium-activated K+ channels in human internal mammary and radial arteries.

  Cardiovascular research 20110201

• Encoding of the cough reflex in anesthetized guinea pigs.

  American journal of physiology. Regulatory, integrative and comparative physiology 20110201

• Microwave assisted synthesis and solid-state characterization of lithocholyl amides of isomeric aminopyridines.

  Steroids 20110201

• Dynamic Kv4.3-CaMKII unit in heart: an intrinsic negative regulator for CaMKII activation.

  European heart journal 20110201

• Imbalanced K+ and Ca2+ subthreshold interactions contribute to increased hypothalamic presympathetic neuronal excitability in hypertensive rats.

  The Journal of physiology 20110201

• Vascular endothelial growth factor up-regulation in the mouse hippocampus and its role in the control of epileptiform activity.

  The European journal of neuroscience 20110201

• Protein kinase A signalling is involved in the relaxant responses to the selective β-oestrogen receptor agonist diarylpropionitrile in rat aortic smooth muscle in vitro.

  The Journal of pharmacy and pharmacology 20110201

• [Pharmacological treatment of nystagmus].

  Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 20110201

• Potassium channel blockers as an effective treatment to restore impulse conduction in injured axons.

  Neuroscience bulletin 20110201

• Leptin enhances nitric oxide-dependent relaxation of the clitoral corpus cavernosum.

  Korean journal of urology 20110201

• 4-Amino-pyridinium-3-sulfonate monohydrate.

  Acta crystallographica. Section E, Structure reports online 20110201

• A Cys-loop mutation in the Caenorhabditis elegans nicotinic receptor subunit UNC-63 impairs but does not abolish channel function.

  The Journal of biological chemistry 20110128

• Ethanol extract of seeds of Oenothera odorata induces vasorelaxation via endothelium-dependent NO-cGMP signaling through activation of Akt-eNOS-sGC pathway.

  Journal of ethnopharmacology 20110127

• Two mechanisms underlie the slow noradrenergic depolarization in the rat tail artery in vitro.

  Autonomic neuroscience : basic & clinical 20110120

• A novel Caenorhabditis elegans allele, smn-1(cb131), mimicking a mild form of spinal muscular atrophy, provides a convenient drug screening platform highlighting new and pre-approved compounds.

  Human molecular genetics 20110115

• Virtual screening identification of nonfolate compounds, including a CNS drug, as antiparasitic agents inhibiting pteridine reductase.

  Journal of medicinal chemistry 20110113

• 4-(Dimethylamino)pyridine as a powerful auxiliary reagent in the electroless synthesis of gold nanotubes.

  Langmuir : the ACS journal of surfaces and colloids 20110104

• Acupuncture's Effects in Treating the Sequelae of Acute and Chronic Spinal Cord Injuries: A Review of Allopathic and Traditional Chinese Medicine Literature.

  Evidence-based complementary and alternative medicine : eCAM 20110101

• Antihypertension Induced by Tanshinone IIA Isolated from the Roots of Salvia miltiorrhiza.

  Evidence-based complementary and alternative medicine : eCAM 20110101

• The conduction block produced by oxcarbazepine in the isolated rat sciatic nerve: a comparison with lamotrigine.

  Neurological research 20110101

• Superoxide differentially controls pulmonary and systemic vascular tone through multiple signalling pathways.

  Cardiovascular research 20110101

• 2-Aminoethoxydiphenyl borate blocks electrical coupling and inhibits voltage-gated K+ channels in guinea pig arteriole cells.

  American journal of physiology. Heart and circulatory physiology 20110101

• Age- and region-specific effects of anticonvulsants and bumetanide on 4-aminopyridine-induced seizure-like events in immature rat hippocampal-entorhinal cortex slices.

  Epilepsia 20110101

• Potassium channel blocker, 4-aminopyridine-3-methanol, restores axonal conduction in spinal cord of an animal model of multiple sclerosis.

  Experimental neurology 20110101

• Effect of intravenous anesthetic propofol on synaptic vesicle exocytosis at the frog neuromuscular junction.

  Acta pharmacologica Sinica 20110101

• Cerebellar Purkinje cells fire paroxysmal depolarization shift (PDS)-like events in response to epileptogenic drugs.

  Neurological research 20110101

• Potassium channels as a potential therapeutic target for trigeminal neuropathic and inflammatory pain.

  Molecular pain 20110101

• Bladder contractility is mediated by different K+ channels in the urothelium and detrusor smooth muscle.

  Journal of pharmacological sciences 20110101

• 4-Aminopyridine: new life for an old drug. Reply.

  Annals of neurology 20110101

• Volume regulated anion channel currents of rat hippocampal neurons and their contribution to oxygen-and-glucose deprivation induced neuronal death.

  PloS one 20110101

• Nuclear translocation of jacob in hippocampal neurons after stimuli inducing long-term potentiation but not long-term depression.

  PloS one 20110101

• Ion channel inhibitors block caspase activation by mechanisms other than restoring intracellular potassium concentration.

  Cell death & disease 20110101

• Real-time CARS imaging reveals a calpain-dependent pathway for paranodal myelin retraction during high-frequency stimulation.

  PloS one 20110101

• The role of Eag and HERG channels in cell proliferation and apoptotic cell death in SK-OV-3 ovarian cancer cell line.

  Cancer cell international 20110101

• Multiple sclerosis therapeutic pipeline: opportunities and challenges.

  The Mount Sinai journal of medicine, New York 20110101

• Patient considerations in the management of multiple sclerosis: development and clinical utility of oral agents.

  Patient preference and adherence 20110101

• Gray matter NG2 cells display multiple Ca2+-signaling pathways and highly motile processes.

  PloS one 20110101

• Enhanced integration of newborn neurons after neonatal insults.

  Frontiers in neuroscience 20110101

• Newborn Analgesia Mediated by Oxytocin during Delivery.

  Frontiers in cellular neuroscience 20110101

• Cellular mechanisms of acute decrease of glutamate release induced by raloxifene in rat cerebral cortex.

  Neuropharmacology 20110101

• Enzyme-carrying electrospun nanofibers.

  Methods in molecular biology (Clifton, N.J.) 20110101

• A computational model of the ionic currents, Ca2+ dynamics and action potentials underlying contraction of isolated uterine smooth muscle.

  PloS one 20110101

• Impact of extended-release dalfampridine on walking ability in patients with multiple sclerosis.

  Neuropsychiatric disease and treatment 20110101

• New synthetic thrombin inhibitors: molecular design and experimental verification.

  PloS one 20110101

• Role of Kv1 potassium channels in regulating dopamine release and presynaptic D2 receptor function.

  PloS one 20110101

• HTDP-2, a new synthetic compound, inhibits glutamate release through reduction of voltage-dependent Ca²⁺ influx in rat cerebral cortex nerve terminals.

  Pharmacology 20110101

• Characteristics of weak base-induced vacuoles formed around individual acidic organelles.

  Folia histochemica et cytobiologica 20110101

• Potassium-induced intermittent vasomotion in rat isolated pulmonary artery.

  Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20110101

• Powerful technique to test selectivity of agents acting on cardiac ion channels: the action potential voltage-clamp.

  Current medicinal chemistry 20110101

• Timing actions to avoid refractoriness: a simple solution for streaming sensory signals.

  PloS one 20110101

• High-level inhibition of mitochondrial complexes III and IV is required to increase glutamate release from the nerve terminal.

  Molecular neurodegeneration 20110101

• Update on treatment options for Lambert-Eaton myasthenic syndrome: focus on use of amifampridine.

  Neuropsychiatric disease and treatment 20110101

• Development and validation of a new method to measure walking speed in free-living environments using the actibelt® platform.

  PloS one 20110101

• Association between walking speed and age in healthy, free-living individuals using mobile accelerometry--a cross-sectional study.

  PloS one 20110101

• Evaluation of candidate genes from orphan FEB and GEFS+ loci by analysis of human brain gene expression atlases.

  PloS one 20110101

• Acute nerve stretch and the compound motor action potential.

  Journal of brachial plexus and peripheral nerve injury 20110101

• 4-aminopyridine induces apoptosis of human acute myeloid leukemia cells via increasing [Ca2+]i through P2X7 receptor pathway.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20110101

• [The influence of ATP-dependent K(+)-channel diazoxide opener on the opening of mitochondrial permeability transition pore in rat liver mitochondria].

  Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20110101

• Targeting VIP and PACAP receptor signalling: new therapeutic strategies in multiple sclerosis.

  ASN neuro 20110101

• Cerebellum and ocular motor control.

  Frontiers in neurology 20110101

• Large Genomic Deletions in CACNA1A Cause Episodic Ataxia Type 2.

  Frontiers in neurology 20110101

• Ca2+ cycling in heart cells from ground squirrels: adaptive strategies for intracellular Ca2+ homeostasis.

  PloS one 20110101

• The A-current modulates learning via NMDA receptors containing the NR2B subunit.

  PloS one 20110101

• Protein 4.1B contributes to the organization of peripheral myelinated axons.

  PloS one 20110101

• Bisphenol A and 17β-estradiol promote arrhythmia in the female heart via alteration of calcium handling.

  PloS one 20110101

• Rem2-targeted shRNAs reduce frequency of miniature excitatory postsynaptic currents without altering voltage-gated Ca²⁺ currents.

  PloS one 20110101

• Disrupted membrane structure and intracellular Ca²⁺ signaling in adult skeletal muscle with acute knockdown of Bin1.

  PloS one 20110101

• Symptomatic therapy and rehabilitation in primary progressive multiple sclerosis.

  Neurology research international 20110101

• HIV-1gp120 induces neuronal apoptosis through enhancement of 4-aminopyridine-senstive outward K+ currents.

  PloS one 20110101

• A human TREK-1/HEK cell line: a highly efficient screening tool for drug development in neurological diseases.

  PloS one 20110101

• Objective assessment of motor fatigue in Multiple Sclerosis using kinematic gait analysis: a pilot study.

  Journal of neuroengineering and rehabilitation 20110101

• Activity of Ca -activated Cl channels contributes to regulating receptor- and store-operated Ca entry in human pulmonary artery smooth muscle cells.

  Pulmonary circulation 20110101

• Acute alterations of somatodendritic action potential dynamics in hippocampal CA1 pyramidal cells after kainate-induced status epilepticus in mice.

  PloS one 20110101

• ROCKing Regeneration: Rho Kinase Inhibition as Molecular Target for Neurorestoration.

  Frontiers in molecular neuroscience 20110101

• Enhanced Synaptic Activity and Epileptiform Events in the Embryonic KCC2 Deficient Hippocampus.

  Frontiers in cellular neuroscience 20110101

• Cholinergic partition cells and lamina x neurons induce a muscarinic-dependent short-term potentiation of commissural glutamatergic inputs in lumbar motoneurons.

  Frontiers in neural circuits 20110101

• Distinct roles of microRNA-1 and -499 in ventricular specification and functional maturation of human embryonic stem cell-derived cardiomyocytes.

  PloS one 20110101

• Onset of Pup Locomotion Coincides with Loss of NR2C/D-Mediated Cortico-Striatal EPSCs and Dampening of Striatal Network Immature Activity.

  Frontiers in cellular neuroscience 20110101

• Simultaneous parasympathetic and sympathetic activation reveals altered autonomic control of heart rate, vascular tension, and epinephrine release in anesthetized hypertensive rats.

  Frontiers in neurology 20110101

• [The role of fast and slow potassium currents in electrical activity of amphibian myelinated nerve fibres].

  Uspekhi fiziologicheskikh nauk 20110101

• Mice null for calsequestrin 1 exhibit deficits in functional performance and sarcoplasmic reticulum calcium handling.

  PloS one 20110101

• Critical state of energy metabolism in brain slices: the principal role of oxygen delivery and energy substrates in shaping neuronal activity.

  Frontiers in neuroenergetics 20110101

• Population diversity and function of hyperpolarization-activated current in olfactory bulb mitral cells.

  Scientific reports 20110101

• Presence and functional role of the rapidly activating delayed rectifier K(+) current in left and right atria of adult mice.

  European journal of pharmacology 20101215

• Orphan drugs. BioMarin Europe replies.

  BMJ (Clinical research ed.) 20101207

• Orphan drugs. Regulation is flawed.

  BMJ (Clinical research ed.) 20101207

• Tyrosinase inhibitory effect of benzoic acid derivatives and their structure-activity relationships.

  Journal of enzyme inhibition and medicinal chemistry 20101201

• Antipruritic activity of extracts of Humulus scandens, the combinations of bioactive flavonoids.

  Fitoterapia 20101201

• Characterization of ionic currents and electrophysiological properties of goldfish somatotropes in primary culture.

  General and comparative endocrinology 20101201

• Action potential bursts in central snail neurons elicited by paeonol: roles of ionic currents.

  Acta pharmacologica Sinica 20101201

• Ocular surface wetness is regulated by TRPM8-dependent cold thermoreceptors of the cornea.

  Nature medicine 20101201

• 4-Amino-pyridinium azide 4-amino-pyridine solvate.

  Acta crystallographica. Section E, Structure reports online 20101201

• Current profiles of astrocytes from the corpus callosum of newborn and 28-day-old rats.

  Neuroscience letters 20101126

• Cortico-hippocampal hyperexcitability in synapsin I/II/III knockout mice: age-dependency and response to the antiepileptic drug levetiracetam.

  Neuroscience 20101124

• Anticonvulsant effect of (E)-2-benzylidene-4-phenyl-1,3-diselenole in a pilocarpine model in mice.

  Life sciences 20101120

• Ionic currents in intimal cultured synoviocytes from the rabbit.

  American journal of physiology. Cell physiology 20101101

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101

• Dalfampridine (Ampyra) for multiple sclerosis.

  The Nurse practitioner 20101101

• 3,4-diaminopyridine for the treatment of Lambert-Eaton myasthenic syndrome.

  Expert review of clinical immunology 20101101

• Contribution of adenosine A(2A) and A(2B) receptors to ischemic coronary dilation: role of K(V) and K(ATP) channels.

  Microcirculation (New York, N.Y. : 1994) 20101101

• The electrocardiogram of a man found in the forest.

  The Netherlands journal of medicine 20101101

• Action potential bursts in central snail neurons elicited by procaine: roles of ionic currents.

  The Chinese journal of physiology 20101031

• Mechanisms of the relaxant effect of a danshen and gegen formulation on rat isolated cerebral basilar artery.

  Journal of ethnopharmacology 20101028

• Mechanisms of vasorelaxation induced by Ziziphora clinopodioides Lam. (Lamiaceae) extract in rat thoracic aorta.

  Journal of ethnopharmacology 20101028

• Merging nucleophilic and hydrogen bonding catalysis: an anion binding approach to the kinetic resolution of propargylic amines.

  Journal of the American Chemical Society 20101006

• Metabolic control of vesicular glutamate transport and release.

  Neuron 20101006

• Differential effects of trimethylamine and quinine on seizures induced by 4-aminopyridine administration in the entorhinal cortex of vigilant rats.

  Seizure 20101001

• Contributory role of endothelium and voltage-gated potassium channels in apocynin-induced vasorelaxations.

  Journal of hypertension 20101001

• Dalfampridine extended release: in multiple sclerosis.

  CNS drugs 20101001

• Possible mechanisms of vasorelaxation for 5,7-dimethoxyflavone from Kaempferia parviflora in the rat aorta.

  Phytotherapy research : PTR 20101001

• A phase 3 trial of extended release oral dalfampridine in multiple sclerosis.

  Annals of neurology 20101001

• High doses of 4-aminopyridine improve functionality in chronic complete spinal cord injury patients with MRI evidence of cord continuity.

  Archives of medical research 20101001

• catena-Poly[[silver(I)-μ-4-aminopyridine] perchlorate]: a 1-D staircase coordination polymer.

  Acta crystallographica. Section E, Structure reports online 20101001

• Dalfampridine (Ampyra) for MS.

  The Medical letter on drugs and therapeutics 20100920

• Exploring the mechanism of endothelial involvement in acidosis-induced vasodilatation of aortic tissues from normal and diabetic rats.

  European journal of pharmacology 20100910

• In vivo 4-aminopyridine treatment alters the neurotoxin 3-acetylpyridine-induced plastic changes in intrinsic electrophysiological properties of rat cerebellar Purkinje neurones.

  European journal of pharmacology 20100910

• Methyl palmitate: a potent vasodilator released in the retina.

  Investigative ophthalmology & visual science 20100901

• K+ currents in isolated vestibular afferent calyx terminals.

  Journal of the Association for Research in Otolaryngology : JARO 20100901

• Voltage-dependent K(+) channels are positive regulators of alpha cell action potential generation and glucagon secretion in mice and humans.

  Diabetologia 20100901

• In vitro ictogenesis and parahippocampal networks in a rodent model of temporal lobe epilepsy.

  Neurobiology of disease 20100901

• Endothelin A receptors mediate relaxation of guinea pig internal anal sphincter through cGMP pathway.

  Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20100901

• Anharmonic vibrational analysis of 3,4-diaminopyridine and 3-aminopyridine by density functional theory calculations.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20100901

• Memantine depresses glutamate release through inhibition of voltage-dependent Ca2+ entry and protein kinase C in rat cerebral cortex nerve terminals: an NMDA receptor-independent mechanism.

  Neurochemistry international 20100901

• Inhibition of spontaneous excitatory transmission induced by codeine is independent on presynaptic K+ channels and novel voltage-dependent Ca2+ channels in the guinea-pig nucleus tractus solitarius.

  Neuroscience 20100901

• Membrane potential-dependent inactivation of voltage-gated ion channels in alpha-cells inhibits glucagon secretion from human islets.

  Diabetes 20100901

• Evidence both L-type and non-L-type voltage-dependent calcium channels contribute to cerebral artery vasospasm following loss of NO in the rat.

  Vascular pharmacology 20100901

• Rho-kinase/ROCK: A key regulator of the cytoskeleton and cell polarity.

  Cytoskeleton (Hoboken, N.J.) 20100901

• The price you pay.

  Drug and therapeutics bulletin 20100901

• Drug-induced changes in action potential duration are proportional to action potential duration in rat ventricular myocardium.

  General physiology and biophysics 20100901

• Synthesis and anticonvulsant activity of certain substituted furochromone, benzofuran and flavone derivatives.

  Chemical & pharmaceutical bulletin 20100901

• Emerging oral agents for multiple sclerosis.

  The American journal of managed care 20100901

• Dalfampridine in multiple sclerosis.

  Drugs of today (Barcelona, Spain : 1998) 20100901

• Chronic progressive multiple sclerosis - pathogenesis of neurodegeneration and therapeutic strategies.

  Current neuropharmacology 20100901

• Bis(4-amino-pyridinium) sulfate monohydrate.

  Acta crystallographica. Section E, Structure reports online 20100901

• Tanshinone IIA modulates pulmonary vascular response to agonist and hypoxia primarily via inhibiting Ca2+ influx and release in normal and hypoxic pulmonary hypertension rats.

  European journal of pharmacology 20100825

• Mechanisms involved in the effects of endothelin-1 in pig prostatic small arteries.

  European journal of pharmacology 20100825

• 3-D-QSAR and docking studies on the neuronal choline transporter.

  Bioorganic & medicinal chemistry letters 20100815

• Integrative emphases on intimate, intrinsic propensity/pathological processes--causes of self recovery limits and also, subtle related targets for neuroprotectionl pleiotropicity/multimodal actions, by accessible therapeutic approaches--in spinal cord injuries.

  Journal of medicine and life 20100815

• alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) antagonists: from bench to bedside.

  Journal of medicinal chemistry 20100812

• Clonidine, an alpha2-receptor agonist, diminishes GABAergic neurotransmission to cardiac vagal neurons in the nucleus ambiguus.

  Brain research 20100806

• A new experimental model of focal seizures in the entorhinal cortex.

  Epilepsia 20100801

• Effects of 3',4'-dihydroxyflavonol on vascular contractions of rat aortic rings.

  Clinical and experimental pharmacology & physiology 20100801

• Intrinsic activation of GABA(A) receptors suppresses epileptiform activity in the cerebral cortex of immature mice.

  Epilepsia 20100801

• Differential involvement of potassium channel subtypes in early and late sepsis-induced hyporesponsiveness to vasoconstrictors.

  Journal of cardiovascular pharmacology 20100801

• Episodic cerebellar dysfunction in a bichon frise: a canine case of episodic ataxia?

  The Journal of small animal practice 20100801

• Drug refractoriness of epileptiform activity in organotypic hippocampal slice cultures depends on the mode of provocation.

  Epilepsy research 20100801

• [Effects of telmisartan on 4-Aminopyridine-sensitive voltage dependant potassium channel of lymphocyte derived from spontaneously hypertensive rat].

  Zhonghua xin xue guan bing za zhi 20100801

• Mechanism of inhibition of acetylcholine secretion in newly formed mouse synapses involving Ca2+-dependent kinases and voltage-gated K+-channels.

  Bulletin of experimental biology and medicine 20100801

• 4-Amino-pyridinium 2-hy-droxy-benzoate.

  Acta crystallographica. Section E, Structure reports online 20100801

• 4-Amino-pyridinium 4-carb-oxy-butano-ate.

  Acta crystallographica. Section E, Structure reports online 20100801

• Astaxanthin inhibits glutamate release in rat cerebral cortex nerve terminals via suppression of voltage-dependent Ca(2+) entry and mitogen-activated protein kinase signaling pathway.

  Journal of agricultural and food chemistry 20100728

• Activation of the cardiac Na(+)-Ca(2+) exchanger by sorcin via the interaction of the respective Ca(2+)-binding domains.

  Journal of molecular and cellular cardiology 20100701

• Modulation of the frequency response of Shaker potassium channels by the quiver peptide suggesting a novel extracellular interaction mechanism.

  Journal of neurogenetics 20100701

• 4-aminopyridine: new life for an old drug.

  Annals of neurology 20100701

• In search of models of pharmacoresistant epilepsy.

  Epilepsia 20100701

• Ligand-exchange processes on solvated zinc cations: water exchange on [Zn(H2O)4(L)]2+.2H2O (L=heterocyclic ligand).

  Chemistry (Weinheim an der Bergstrasse, Germany) 20100625

• [Expression and properties of potassium channels in human mammary epithelial cell line MCF10A and its possible role in proliferation].

  Sheng li xue bao : [Acta physiologica Sinica] 20100625

• Intrinsic membrane properties of pre-oromotor neurons in the intermediate zone of the medullary reticular formation.

  Neuroscience 20100616

• Endothelium-dependent and -independent vasorelaxation induced by CIJ-3-2F, a novel benzyl-furoquinoline with antiarrhythmic action, in rat aorta.

  Life sciences 20100605

• Bursts and hyperexcitability in non-myelinated axons of the rat hippocampus.

  Neuroscience 20100602

• Isolation of somatic Na+ currents by selective inactivation of axonal channels with a voltage prepulse.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20100602

• KChIP2 attenuates cardiac hypertrophy through regulation of Ito and intracellular calcium signaling.

  Journal of molecular and cellular cardiology 20100601

• 3,4-diaminopyridine safety in clinical practice: an observational, retrospective cohort study.

  Journal of neurology 20100601

• HL-1 cells express an inwardly rectifying K+ current activated via muscarinic receptors comparable to that in mouse atrial myocytes.

  Pflugers Archiv : European journal of physiology 20100601

• Effects of hydroxamate metalloendoprotease inhibitors on botulinum neurotoxin A poisoned mouse neuromuscular junctions.

  Neuropharmacology 20100601

• Differences in Na+ conductance density and Na+ channel functional properties between dopamine and GABA neurons of the rat substantia nigra.

  Journal of neurophysiology 20100601

• Normal targeting of a tagged Kv1.5 channel acutely transfected into fresh adult cardiac myocytes by a biolistic method.

  American journal of physiology. Cell physiology 20100601

• Compression induces acute demyelination and potassium channel exposure in spinal cord.

  Journal of neurotrauma 20100601

• Regional differences in nerve terminal Na+ channel subtype expression and Na+ channel-dependent glutamate and GABA release in rat CNS.

  Journal of neurochemistry 20100601

• Current therapy for Lambert-Eaton myasthenic syndrome: development of 3,4-diaminopyridine phosphate salt as first-line symptomatic treatment.

  Current medical research and opinion 20100601

• Characterization of voltage-gated K+ currents contributing to subthreshold membrane potential oscillations in hippocampal CA1 interneurons.

  Journal of neurophysiology 20100601

• Effects of K+channels inhibitors on the cholinergic relaxation of the isolated aorta of adult offspring rats exposed to maternal diabetes.

  Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20100601

• Comparative hemodynamic effects of levosimendan alone and in conjunction with 4-aminopyridine or calcium chloride in a rodent model of severe verapamil poisoning.

  Journal of medical toxicology : official journal of the American College of Medical Toxicology 20100601

• Synthesis, crystal structure and magnetic properties of two oxalato-bridged dimetallic trinuclear complexes combined with a polar cation.

  Dalton transactions (Cambridge, England : 2003) 20100528

• The therapeutic mode of action of 4-aminopyridine in cerebellar ataxia.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20100526

• Hypericin, the active component of St. John's wort, inhibits glutamate release in the rat cerebrocortical synaptosomes via a mitogen-activated protein kinase-dependent pathway.

  European journal of pharmacology 20100525

• The effect of 3,4-diaminopyridine on the patients with hereditary pure cerebellar ataxia.

  Journal of the neurological sciences 20100515

• Calcium oscillations induced by gambierol in cerebellar granule cells.

  Journal of cellular biochemistry 20100515

• Diverse antiepileptic drugs increase the ratio of background synaptic inhibition to excitation and decrease neuronal excitability in neurones of the rat entorhinal cortex in vitro.

  Neuroscience 20100505

• Local control of postinhibitory rebound spiking in CA1 pyramidal neuron dendrites.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20100505

• From learning to forgetting: behavioral, circuitry, and molecular properties define the different functional states of the recognition memory trace.

  Hippocampus 20100501

• NR2D-containing NMDA receptors mediate tissue plasminogen activator-promoted neuronal excitotoxicity.

  Cell death and differentiation 20100501

• Acute restraint stress enhances calcium mobilization and glutamate exocytosis in cerebrocortical synaptosomes from mice.

  Neurochemical research 20100501

• Investigation of selective molecular interactions using two-dimensional Fourier transform IR spectroscopy.

  Analytical and bioanalytical chemistry 20100501

• Functional ion channels in mouse cardiac c-kit(+) cells.

  American journal of physiology. Cell physiology 20100501

• Effects of sex and estrogen on chicken ductus arteriosus reactivity.

  American journal of physiology. Regulatory, integrative and comparative physiology 20100501

• Independent epileptiform discharge patterns in the olfactory and limbic areas of the in vitro isolated Guinea pig brain during 4-aminopyridine treatment.

  Journal of neurophysiology 20100501

• Water-soluble PDE4 inhibitors for the treatment of dry eye.

  Bioorganic & medicinal chemistry letters 20100501

• The role of nitric oxide and potassium channels in the effect of adrenomedullin in human internal thoracic arteries.

  Regulatory peptides 20100409

• Communication between thiamin cofactors in the Escherichia coli pyruvate dehydrogenase complex E1 component active centers: evidence for a 'direct pathway' between the 4'-aminopyrimidine N1' atoms.

  The Journal of biological chemistry 20100409

• Ion transport in a human lens epithelial cell line exposed to hyposmotic and apoptotic stress.

  Journal of cellular physiology 20100401

• Hypoxia sensing in the fetal chicken femoral artery is mediated by the mitochondrial electron transport chain.

  American journal of physiology. Regulatory, integrative and comparative physiology 20100401

• Metabolic syndrome reduces the contribution of K+ channels to ischemic coronary vasodilation.

  American journal of physiology. Heart and circulatory physiology 20100401

• Spadin, a sortilin-derived peptide, targeting rodent TREK-1 channels: a new concept in the antidepressant drug design.

  PLoS biology 20100401

• An excitatory loop with astrocytes contributes to drive neurons to seizure threshold.

  PLoS biology 20100401

• [Lambert-Eaton myasthenic syndrome (LEMS)].

  Brain and nerve = Shinkei kenkyu no shinpo 20100401

• [Development of oral therapies for multiple sclerosis--fingolimod, cladribine and other drugs].

  Medizinische Monatsschrift fur Pharmazeuten 20100401

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20100401

• CXCL12 inhibits expression of the NMDA receptor's NR2B subunit through a histone deacetylase-dependent pathway contributing to neuronal survival.

  Cell death & disease 20100401

• 4-Amino-pyridinium picrate.

  Acta crystallographica. Section E, Structure reports online 20100401

• 4-(Methyl-amino)pyridine.

  Acta crystallographica. Section E, Structure reports online 20100401

• Distribution and role of Kv3.1b in neurons in the medial septum diagonal band complex.

  Neuroscience 20100331

• Evaluation of the sesquiterpene (-)-alpha-bisabolol as a novel peripheral nervous blocker.

  Neuroscience letters 20100312

• [Progress of therapy in patients with multiple sclerosis].

  MMW Fortschritte der Medizin 20100304

• Effects of 4-aminopyridine on organelle movement in cultured mouse dorsal root ganglion neurites.

  Journal of molecular neuroscience : MN 20100301

• Antiepileptic drugs abolish ictal but not interictal epileptiform discharges in vitro.

  Epilepsia 20100301

• Neural stem/progenitor cells derived from the embryonic dorsal telencephalon of D6/GFP mice differentiate primarily into neurons after transplantation into a cortical lesion.

  Cellular and molecular neurobiology 20100301

• Flufenamic acid suppresses epileptiform activity in hippocampus by reducing excitatory synaptic transmission and neuronal excitability.

  Epilepsia 20100301

• Electrophysiological properties of human induced pluripotent stem cells.

  American journal of physiology. Cell physiology 20100301

• Tetramerization domain mutations in KCNA5 affect channel kinetics and cause abnormal trafficking patterns.

  American journal of physiology. Cell physiology 20100301

• Downregulated Kv4.3 expression in the RVLM as a potential mechanism for sympathoexcitation in rats with chronic heart failure.

  American journal of physiology. Heart and circulatory physiology 20100301

• Transient outward potassium current in ICC.

  American journal of physiology. Gastrointestinal and liver physiology 20100301

• Property of I(K,)(n) in inner hair cells isolated from guinea-pig cochlea.

  Hearing research 20100301

• Dalfampridine approved for MS.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20100301

• Abstracts of the 16th Annual Society on NeuroImmune Pharmacology (SNIP) Conference. April 13-17, 2010. Manhattan Beach, California, USA.

  Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 20100301

• Phentolamine inhibits the pacemaker activity of mouse interstitial cells of Cajal by activating ATP-sensitive K+ channels.

  Archives of pharmacal research 20100301

• Past, present and future therapeutics for cerebellar ataxias.

  Current neuropharmacology 20100301

• Mechanisms of action of hydrogen sulfide in relaxation of mouse distal colonic smooth muscle.

  European journal of pharmacology 20100225

• Phospholipase C-independent effects of 3M3FBS in murine colon.

  European journal of pharmacology 20100225

• [The modulation of 4-aminopyridine sensitive potassium channel to bifurcation scenario of the spontaneous neural firing rhythms].

  Sheng li xue bao : [Acta physiologica Sinica] 20100225

• Suppression of the intrinsic apoptosis pathway by synaptic activity.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20100217

• Multiple effects of 4-aminopyridine on feline and rabbit sinoatrial node myocytes and multicellular preparations.

  Pflugers Archiv : European journal of physiology 20100201

• Cannabidiol displays antiepileptiform and antiseizure properties in vitro and in vivo.

  The Journal of pharmacology and experimental therapeutics 20100201

• Region- and pattern-specific effects of glutamate uptake blockers on epileptiform activity in rat brain slices.

  Epilepsy research 20100201

• Development of K(+) and Na(+) conductances in rodent postnatal semicircular canal type I hair cells.

  American journal of physiology. Regulatory, integrative and comparative physiology 20100201

• Quantification of 4-aminopyridine in plasma by capillary electrophoresis with electrokinetic injection.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100201

• Single-Dose pharmacokinetics of sustained-release fampridine (Fampridine-SR) in healthy volunteers and adults with renal impairment.

  Journal of clinical pharmacology 20100201

• [4-Aminopyridine (Fampridine). A new attempt for the symptomatic treatment of multiple sclerosis].

  Der Nervenarzt 20100201

• MLCK and PKC Involvements via Gi and Rho A Protein in Contraction by the Electrical Field Stimulation in Feline Esophageal Smooth Muscle.

  The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 20100201

• Secondhand smoke exposure alters K+ channel function and intrinsic cell excitability in a subset of second-order airway neurons in the nucleus tractus solitarius of young guinea pigs.

  The European journal of neuroscience 20100201

• Cellular coupling of potassium channels with beta2 adrenoceptors in mediating myometrial relaxation in buffaloes (Bubalus bubalis).

  Journal of veterinary pharmacology and therapeutics 20100201

• Human embryonic stem cell neural differentiation and enhanced cell survival promoted by hypoxic preconditioning.

  Cell death & disease 20100201

• Benzyl N-(4-pyrid-yl)carbamate.

  Acta crystallographica. Section E, Structure reports online 20100201

• Apamin reduces neuromuscular transmission by activating inhibitory muscarinic M(2) receptors on motor nerve terminals.

  European journal of pharmacology 20100125

• Development of multi-electrode array screening for anticonvulsants in acute rat brain slices.

  Journal of neuroscience methods 20100115

• Rebound bursts in GABAergic neurons of the thalamic reticular nucleus in postnatal mice.

  Physiological research 20100101

• Optical suppression of experimental seizures in rat brain slices.

  Epilepsia 20100101

• Increased basal synaptic inhibition of hippocampal area CA1 pyramidal neurons by an antiepileptic drug that enhances I(H).

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20100101

• Elementary properties of CaV1.3 Ca(2+) channels expressed in mouse cochlear inner hair cells.

  The Journal of physiology 20100101

• Novel potassium channel blocker, 4-AP-3-MeOH, inhibits fast potassium channels and restores axonal conduction in injured guinea pig spinal cord white matter.

  Journal of neurophysiology 20100101

• Block of mouse Slo1 and Slo3 K+ channels by CTX, IbTX, TEA, 4-AP and quinidine.

  Channels (Austin, Tex.) 20100101

• Vacuoles: a hollow threat?

  Canadian journal of anaesthesia = Journal canadien d'anesthesie 20100101

• Improvement of diaphragm and limb muscle isotonic contractile performance by K+ channel blockade.

  Journal of neuroengineering and rehabilitation 20100101

• Involvement of the 4-aminopyridine-sensitive transient A-type K+ current in macrophage-induced neuronal injury.

  The European journal of neuroscience 20100101

• Atrial natriuretic peptide regulates Ca channel in early developmental cardiomyocytes.

  PloS one 20100101

• Superoxidedismutase-mimetic copper(II) complexes containing saccharinate and 4-aminopyridine/4-cyanopyridine.

  Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 20100101

• Presynaptic calcium signalling in cerebellar mossy fibres.

  Frontiers in neural circuits 20100101

• Nitroprusside modulates pulmonary vein arrhythmogenic activity.

  Journal of biomedical science 20100101

• Matrix metalloproteinase-9 activity increased by two different types of epileptic seizures that do not induce neuronal death: a possible role in homeostatic synaptic plasticity.

  Neurochemistry international 20100101

• Nerve terminal degeneration is independent of muscle fiber genotype in SOD1 mice.

  PloS one 20100101

• Voltage-gated K+ currents in mouse articular chondrocytes regulate membrane potential.

  Channels (Austin, Tex.) 20100101

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20100101

• 4-aminopyridine-sensitive K+ channels contributes to NaHS-induced membrane hyperpolarization and relaxation in the rat coronary artery.

  Vascular pharmacology 20100101

• New drugs: Liraglutide, dalfampridine, and abobotulinumtoxinA.

  Journal of the American Pharmacists Association : JAPhA 20100101

• Vasodilator effect of Cassiarin A, a novel antiplasmodial alkaloid from Cassia siamea, in rat isolated mesenteric artery.

  Biological & pharmaceutical bulletin 20100101

• Vasorelaxant effects of Clearfil SE Bond and Clearfil S(3) Bond mediated by calcium antagonistic action.

  Journal of biomaterials science. Polymer edition 20100101

• Cerebral hemodynamic responses to seizure in the mouse brain: simultaneous near-infrared spectroscopy-electroencephalography study.

  Journal of biomedical optics 20100101

• Endothelium-independent vasorelaxation by Ligusticum wallichii in isolated rat aorta: comparison of a butanolic fraction and tetramethylpyrazine, the main active component of Ligusticum wallichii.

  Biological & pharmaceutical bulletin 20100101

• Checks and balances in neuromodulation.

  Frontiers in behavioral neuroscience 20100101

• Temporal coding at the immature depolarizing GABAergic synapse.

  Frontiers in cellular neuroscience 20100101

• Optical mapping of release properties in synapses.

  Frontiers in neural circuits 20100101

• Human neural stem cells differentiate and promote locomotor recovery in an early chronic spinal cord injury NOD-scid mouse model.

  PloS one 20100101

• Strategies for study of neuroprotection from cold-preconditioning.

  Journal of visualized experiments : JoVE 20100101

• High-density expression of Ca2+-permeable ASIC1a channels in NG2 glia of rat hippocampus.

  PloS one 20100101

• Vasorelaxation induced by amodiaquine in rat superior mesenteric arteries: in vivo and in vitro studies.

  Acta poloniae pharmaceutica 20100101

• Clostridium perfringens epsilon toxin targets granule cells in the mouse cerebellum and stimulates glutamate release.

  PloS one 20100101

• Pharmacological Preconditioning with GYKI 52466: A Prophylactic Approach to Neuroprotection.

  Frontiers in neuroscience 20100101

• Novel HTS strategy identifies TRAIL-sensitizing compounds acting specifically through the caspase-8 apoptotic axis.

  PloS one 20100101

• Feasibility of combination allogeneic stem cell therapy for spinal cord injury: a case report.

  International archives of medicine 20100101

• Muscle receptor organs in the crayfish abdomen: a student laboratory exercise in proprioception.

  Journal of visualized experiments : JoVE 20100101

• The Eag potassium channel as a new prognostic marker in ovarian cancer.

  Diagnostic pathology 20100101

• Testosterone and cholesterol vasodilation of rat aorta involves L-type calcium channel inhibition.

  Advances in pharmacological sciences 20100101

• New approaches in the management of multiple sclerosis.

  Drug design, development and therapy 20100101

• DREAM regulates BDNF-dependent spinal sensitization.

  Molecular pain 20100101

• New methods for diagnosis and treatment of vestibular diseases.

  F1000 medicine reports 20100101

• Walking impairment in patients with multiple sclerosis: exercise training as a treatment option.

  Neuropsychiatric disease and treatment 20100101

• Quinidine depresses the transmural electrical heterogeneity of transient outward potassium current of the right ventricular outflow tract free wall.

  Journal of cardiovascular disease research 20100101

• Eye disorders in patients with multiple sclerosis: natural history and management.

  Clinical ophthalmology (Auckland, N.Z.) 20100101

• From the bench to the bedside: Breaking down the blood-brain barrier, decoding the habenula, understanding hand choice, and the role of ketone bodies in epilepsy.

  Surgical neurology international 20100101

• Re-evaluation of the action potential upstroke velocity as a measure of the Na+ current in cardiac myocytes at physiological conditions.

  PloS one 20100101

• Functional roles of distributed synaptic clusters in the mitral-granule cell network of the olfactory bulb.

  Frontiers in integrative neuroscience 20100101

• Kv1.5 in the immune system: the good, the bad, or the ugly?

  Frontiers in physiology 20100101

• Dalfampridine sustained-release for symptomatic improvement of walking speed in patients with multiple sclerosis.

  Core evidence 20100101

• [Effect of 4-aminopyridine-sensitive potassium current on high frequency tonic firing of the rat retinal ganglion cells].

  Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20100101

• Aminopyridines potentiate synaptic and neuromuscular transmission by targeting the voltage-activated calcium channel beta subunit.

  The Journal of biological chemistry 20091225

• Changing the 'channel': aminopyridines potentiate synaptic and neuromuscular transmission by targeting the voltage-activated calcium channel beta subunit.

  The Journal of biological chemistry 20091225

• Input-specific GABAergic signaling to newborn neurons in adult dentate gyrus.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20091202

• Transduction mechanism(s) of Na-saccharin in the blowfly Protophormia terraenovae: evidence for potassium and calcium conductance involvement.

  Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology 20091201

• Neither K+ channels nor PI3K/Akt mediates the vasodilative effect of nebivolol on different types of rat arteries.

  Journal of cardiovascular pharmacology and therapeutics 20091201

• Hydrogen peroxide affects contractile activity and anti-oxidant enzymes in rat uterus.

  British journal of pharmacology 20091201

• Characterization of TWIK-2, a two-pore domain K+ channel, cloned from the rat middle cerebral artery.

  Experimental biology and medicine (Maywood, N.J.) 20091201

• Assessment of the cardiac safety of fampridine-SR sustained-release tablets in a thorough QT/QTc evaluation at therapeutic and supratherapeutic doses in healthy individuals.

  Expert opinion on investigational drugs 20091201

• Potassium induced dilation in bovine coronary artery involves both inward rectifier potassium channels and Na+ /K+ ATPase.

  Acta physiologica Hungarica 20091201

• Nitric oxide modulation of GABAergic synaptic transmission in mechanically isolated rat auditory cortical neurons.

  The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 20091201

• 4-Aminopyridine catalyzed direct and regioselective acylation of N-tosylhydrazide.

  Organic letters 20091105

• In Vitro electrophysiological activity of nerispirdine, a novel 4-aminopyridine derivative.

  Clinical and experimental pharmacology & physiology 20091101

• Lysophosphatidylcholine- and MCP-1-induced chemotaxis of monocytes requires potassium channel activity.

  Pflugers Archiv : European journal of physiology 20091101

• 3,4-Diaminopyridine is more effective than placebo in a randomized, double-blind, cross-over drug study in LEMS.

  Muscle & nerve 20091101

• Experience-dependent intrinsic plasticity in interneurons of barrel cortex layer IV.

  Journal of neurophysiology 20091101

• Modulation of noradrenergic neurotransmission in isolated rat radial artery.

  Journal of pharmacological sciences 20091101

• Heparin and suramin alter plitidepsin uptake via inhibition of GPCR coupled signaling.

  Journal of chemotherapy (Florence, Italy) 20091101

• [Dynamic research shows significant therapeutic advances].

  Soins; la revue de reference infirmiere 20091101

• 2-Amino-5-chloro-pyridinium nitrate.

  Acta crystallographica. Section E, Structure reports online 20091101

• Membrane current-based mechanisms for excitability transitions in neurons of the rat mesencephalic trigeminal nuclei.

  Neuroscience 20091020

• Preconditioning with 4-aminopyridine protects cerebellar granule neurons against excitotoxicity.

  Brain research 20091019

• Effects of gamma-aminobutyric acid (GABA) agonists and a GABA uptake inhibitor on pharmacoresistant seizure like events in organotypic hippocampal slice cultures.

  Epilepsy research 20091001

• Management of myasthenic conditions: nonimmune issues.

  Current opinion in neurology 20091001

• A multi PDZ-domain protein Pdzd2 contributes to functional expression of sensory neuron-specific sodium channel Na(V)1.8.

  Molecular and cellular neurosciences 20091001

• Maturation of O2 sensing and signaling in the chicken ductus arteriosus.

  American journal of physiology. Lung cellular and molecular physiology 20091001

• The effects of dehydroepiandrosterone (DHEA)/DHEA-sulfate (DHEAS) on the contraction responses of the clitoral cavernous smooth muscle from female rabbits.

  The journal of sexual medicine 20091001

• Pyridoxine inhibits depolarization-evoked glutamate release in nerve terminals from rat cerebral cortex: a possible neuroprotective mechanism?

  The Journal of pharmacology and experimental therapeutics 20091001

• Excitatory roles of protein kinase C in striatal cholinergic interneurons.

  Journal of neurophysiology 20091001

• Pharmacokinetics of 4-aminopyridine derivatives in dogs.

  Journal of veterinary pharmacology and therapeutics 20091001

• Apple procyanidins induced vascular relaxation in isolated rat aorta through NO/cGMP pathway in combination with hyperpolarization by multiple K+ channel activations.

  Bioscience, biotechnology, and biochemistry 20091001

• Pharmacokinetics and tolerability of single escalating doses of fampridine sustained-release tablets in patients with multiple sclerosis: a Phase I-II, open-label trial.

  Clinical therapeutics 20091001

• Steady-state pharmacokinetics and tolerability of orally administered fampridine sustained-release 10-mg tablets in patients with multiple sclerosis: a 2-week, open-label, follow-up study.

  Clinical therapeutics 20091001

• catena-Poly[bis-(4-amino-pyridinium) [[tetra-aqua-nickel(II)]-μ-benzene-1,2,4,5-tetra-carboxyl-ato] dihydrate].

  Acta crystallographica. Section E, Structure reports online 20091001

• Repeated 4-aminopyridine induced seizures diminish the efficacy of glutamatergic transmission in the neocortex.

  Experimental neurology 20090901

• 4-Aminopyridine improves spatial memory in a murine model of HIV-1 encephalitis.

  Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 20090901

• Modulation of presynaptic glucocorticoid receptors on glutamate release from rat hippocampal nerve terminals.

  Synapse (New York, N.Y.) 20090901

• Facilitation of glutamate release from rat cerebral cortex nerve terminal by subanesthetic concentration propofol.

  Synapse (New York, N.Y.) 20090901

• Impaired voltage gated potassium channel responses in a fetal lamb model of persistent pulmonary hypertension of the newborn.

  Pediatric research 20090901

• Reduction of repolarization reserve unmasks the proarrhythmic role of endogenous late Na(+) current in the heart.

  American journal of physiology. Heart and circulatory physiology 20090901

• Regulation of intracerebral arteriolar tone by K(v) channels: effects of glucose and PKC.

  American journal of physiology. Cell physiology 20090901

• Synthesis and evaluation of a series of 2,4-diaminopyridine derivatives as potential positron emission tomography tracers for neuropeptide Y Y1 receptors.

  Bioorganic & medicinal chemistry letters 20090901

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20090901

• Effects of 4-Aminopyridine on Cloned hERG Channels Expressed in Mammalian Cells.

  Archives of drug information 20090901

• Dual effect of exogenous hydrogen sulfide on the spontaneous contraction of gastric smooth muscle in guinea-pig.

  European journal of pharmacology 20090815

• Endothelial and potassium channel dependent modulation of noradrenergic vasoconstriction in the pig radial artery.

  European journal of pharmacology 20090815

• Allosteric interaction of the anticholinergic drug [N-(4-phenyl)-phenacyl-l-hyoscyamine] (Phenthonium) with nicotinic receptors of post-ganglionic sympathetic neurons of the rat vas deferens.

  European journal of pharmacology 20090815

• Thermoplastic cellulose-graft-poly(L-lactide) copolymers homogeneously synthesized in an ionic liquid with 4-dimethylaminopyridine catalyst.

  Biomacromolecules 20090810

• Aging and muscle fiber type alter K+ channel contributions to the myogenic response in skeletal muscle arterioles.

  Journal of applied physiology (Bethesda, Md. : 1985) 20090801

• Somatostatin release, electrical activity, membrane currents and exocytosis in human pancreatic delta cells.

  Diabetologia 20090801

• L-aspartate as an amino acid neurotransmitter: mechanisms of the depolarization-induced release from cerebrocortical synaptosomes.

  Journal of neurochemistry 20090801

• Peripheral nerve at extreme low temperatures 2: pharmacologic modulation of temperature effects.

  Cryobiology 20090801

• Peripheral nerve at extreme low temperatures 1: effects of temperature on the action potential.

  Cryobiology 20090801

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  Expert opinion on pharmacotherapy 20090801

• Nuclear calcium signaling controls expression of a large gene pool: identification of a gene program for acquired neuroprotection induced by synaptic activity.

  PLoS genetics 20090801

• Treating epilepsy via adaptive neurostimulation: a reinforcement learning approach.

  International journal of neural systems 20090801

• catena-Poly[bis-(4-amino-pyridinium) [[diaqua-manganese(II)]-di-μ-chlorido] dichloride].

  Acta crystallographica. Section E, Structure reports online 20090801

• Hypotensive and endothelium-independent vasorelaxant effects of methanolic extract from Curcuma longa L. in rats.

  Journal of ethnopharmacology 20090730

• Neocortical disynaptic inhibition requires somatodendritic integration in interneurons.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20090715

• A potent and nitric oxide-dependent hypotensive effect induced in rats by semi-purified fractions from Maytenus ilicifolia.

  Vascular pharmacology 20090701

• Identification of Ikr kinetics and drug binding in native myocytes.

  Annals of biomedical engineering 20090701

• Efficacy of 3,4-diaminopyridine and pyridostigmine in the treatment of Lambert-Eaton myasthenic syndrome: a randomized, double-blind, placebo-controlled, crossover study.

  Clinical pharmacology and therapeutics 20090701

• Testosterone might cause relaxation of human corpus cavernosum by potassium channel opening action.

  Urology 20090701

• Fangchinoline inhibits glutamate release from rat cerebral cortex nerve terminals (synaptosomes).

  Neurochemistry international 20090701

• Inhibitory effect of glutamate release from rat cerebrocortical synaptosomes by dextromethorphan and its metabolite 3-hydroxymorphinan.

  Neurochemistry international 20090701

• Characteristics of rostral solitary tract nucleus neurons with identified afferent connections that project to the parabrachial nucleus in rats.

  Journal of neurophysiology 20090701

• Design, synthesis and structure-activity relationships of (1H-pyridin-4-ylidene)amines as potential antimalarials.

  Bioorganic & medicinal chemistry letters 20090701

• Sustained-release fampridine for multiple sclerosis.

  Expert opinion on investigational drugs 20090701

• 4-Aminopyridinium 4-aminobenzoate dihydrate and 4-aminopyridinium nicotinate.

  Acta crystallographica. Section C, Crystal structure communications 20090701

• Total synthesis of 4-acetyl-1,3-dihydroimidazo[4,5-c]pyridin-2-one, a new microbial metabolite from a Streptomyces species.

  Natural product communications 20090701

• Improved copper(I)-NHC catalytic efficiency on huisgen reaction by addition of aromatic nitrogen donors.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20090622

• Dihydropyridine block of voltage-dependent K+ currents in rat dorsal root ganglion neurons.

  Neuroscience 20090616

• Effect of acidosis on the mechanism(s) of insulin-induced vasorelaxation in normal Wistar-Kyoto (WKY) rat aorta.

  Regulatory peptides 20090605

• Retrograde opioid signaling regulates glutamatergic transmission in the hypothalamus.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20090603

• Electrophysiological properties of octopus neurons of the cat cochlear nucleus: an in vitro study.

  Journal of the Association for Research in Otolaryngology : JARO 20090601

• A role for nitroxyl (HNO) as an endothelium-derived relaxing and hyperpolarizing factor in resistance arteries.

  British journal of pharmacology 20090601

• Network-based activity induced by 4-aminopyridine in rat dorsal horn in vitro is mediated by both chemical and electrical synapses.

  The Journal of physiology 20090601

• Conformational isomers of the [(5-methyl-2-pyridinio)aminomethylene]diphosphonate dianion and [(5-methyl-2-pyridyl)aminomethylene]diphosphonate trianion in salts with 4-aminopyridine and ammonia.

  Acta crystallographica. Section C, Crystal structure communications 20090601

• Brain-derived neurotrophic factor and electrophysiological properties of voltage-gated ion channels during neuronal stem cell development.

  Brain research 20090526

• N-acetylcysteine-induced vasodilation involves voltage-gated potassium channels in rat aorta.

  Life sciences 20090522

• A1 receptors mediate adenosine inhibitory effects in mouse ileum via activation of potassium channels.

  Life sciences 20090522

• A general screening strategy for peptide-based fluorogenic ligands: probes for dynamic studies of PDZ domain-mediated interactions.

  Journal of the American Chemical Society 20090520

• Loss of functional K+ channels encoded by ether-à-go-go-related genes in mouse myometrium prior to labour onset.

  The Journal of physiology 20090515

• Motor cortex bilateral motor representation depends on subcortical and interhemispheric interactions.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20090513

• Redox variants of NO (NO{middle dot} and HNO) elicit vasorelaxation of resistance arteries via distinct mechanisms.

  American journal of physiology. Heart and circulatory physiology 20090501

• Endothelium-independent vasorelaxation by the selective alpha estrogen receptor agonist propyl pyrazole triol in rat aortic smooth muscle.

  The Journal of pharmacy and pharmacology 20090501

• 10 questions about 4-aminopyridine and the treatment of multiple sclerosis.

  The neurologist 20090501

• Bis(4-amino-pyridinium) tetra-chlorido-cobaltate(II).

  Acta crystallographica. Section E, Structure reports online 20090501

• Seletracetam (ucb 44212) inhibits high-voltage-activated Ca2+ currents and intracellular Ca2+ increase in rat cortical neurons in vitro.

  Epilepsia 20090401

• Isoliquiritigenin, a flavonoid from licorice, plays a dual role in regulating gastrointestinal motility in vitro and in vivo.

  Phytotherapy research : PTR 20090401

• Properties and ionic mechanisms of action potential adaptation, restitution, and accommodation in canine epicardium.

  American journal of physiology. Heart and circulatory physiology 20090401

• Evidence for a critical period in the development of excitability and potassium currents in mouse lumbar superficial dorsal horn neurons.

  Journal of neurophysiology 20090401

• Automated potentiometric titrations in KCl/water-saturated octanol: method for quantifying factors influencing ion-pair partitioning.

  Analytical chemistry 20090401

• Characterizing the mechanisms of insulin vasodilatation of normal and streptozotocin-induced diabetic rat aorta.

  Journal of cardiovascular pharmacology 20090401

• The therapeutic potential of focal cooling for neocortical epilepsy.

  Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 20090401

• Anticonvulsant and antiepileptic actions of 2-deoxy-D-glucose in epilepsy models.

  Annals of neurology 20090401

• Bis(4-amino-pyridinium) bis(hydrogen oxalate) monohydrate.

  Acta crystallographica. Section E, Structure reports online 20090401

• 4-Amino-pyridinium hydrogen succinate.

  Acta crystallographica. Section E, Structure reports online 20090401

• 2-(4-Amino-pyridinio)acetate.

  Acta crystallographica. Section E, Structure reports online 20090401

• Anticonvulsant properties of saponins from Ficus platyphylla stem bark.

  Brain research bulletin 20090330

• Activity-dependent control of neuronal output by local and global dendritic spike attenuation.

  Neuron 20090326

• 4-Aminopyridine toxicity mimics autoimmune-mediated limbic encephalitis.

  Neurology 20090324

• 2,4-Diaminopyridine delta-opioid receptor agonists and their associated hERG pharmacology.

  Bioorganic & medicinal chemistry letters 20090315

• Myosin light chain phosphatase activation is involved in the hydrogen sulfide-induced relaxation in mouse gastric fundus.

  European journal of pharmacology 20090315

• Spatiotemporal dynamics of perfusion and oximetry during ictal discharges in the rat neocortex.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20090304

• 5-HT inhibition of rat insulin 2 promoter Cre recombinase transgene and proopiomelanocortin neuron excitability in the mouse arcuate nucleus.

  Neuroscience 20090303

• Modification of ionotropic glutamate receptor-mediated processes in the rat hippocampus following repeated, brief seizures.

  Neuroscience 20090303

• Nicotinic and muscarinic cholinergic receptors coexist on GABAergic nerve endings in the mouse striatum and interact in modulating GABA release.

  Neuropharmacology 20090301

• Facilitation of glutamate release from rat cerebrocortical glutamatergic nerve terminals (synaptosomes) by phosphatidylserine and phosphatidylcholine.

  Synapse (New York, N.Y.) 20090301

• Quantitative assessment of the distributions of membrane conductances involved in action potential backpropagation along basal dendrites.

  Journal of neurophysiology 20090301

• Pre-synaptic nicotinic and D receptors functionally interact on dopaminergic nerve endings of rat and mouse nucleus accumbens.

  Journal of neurochemistry 20090301

• Molecular mechanism of KCl-induced relaxation of the esophagus.

  European journal of pharmacology 20090301

• Epileptiform synchronization in the cingulate cortex.

  Epilepsia 20090301

• Nicotinic receptor-evoked hippocampal norepinephrine release is highly sensitive to inhibition by isoflurane.

  British journal of anaesthesia 20090301

• Deleting the accessory subunit KChIP2 results in loss of I(to,f) and increased I(K,slow) that maintains normal action potential configuration.

  Heart rhythm 20090301

• Synchronous GABA-receptor-dependent potentials in limbic areas of the in-vitro isolated adult guinea pig brain.

  The European journal of neuroscience 20090301

• Partial compensation for N-type Ca(2+) channel loss by P/Q-type Ca(2+) channels underlines the differential release properties supported by these channels at cerebrocortical nerve terminals.

  The European journal of neuroscience 20090301

• An unusual case of 4-aminopyridine toxicity in a multiple sclerosis patient: epileptic disorder or toxic encephalopathy?

  Acta neurologica Belgica 20090301

• Impact of pesticides use in agriculture: their benefits and hazards.

  Interdisciplinary toxicology 20090301

• Improving function: a new treatment era for multiple sclerosis?

  Lancet (London, England) 20090227

• Sustained-release oral fampridine in multiple sclerosis: a randomised, double-blind, controlled trial.

  Lancet (London, England) 20090227

• Ligand-selective photodissociation from [Ru(bpy)(4AP)4]2+: a spectroscopic and computational study.

  Inorganic chemistry 20090216

• N-(4-pyridyl) methyl carbamate inhibits fast potassium currents in guinea pig dorsal root ganglion cells.

  Journal of the neurological sciences 20090215

• Stabilizing effects of eicosapentaenoic acid on Kv1.5 channel protein expressed in mammalian cells.

  European journal of pharmacology 20090214

• Controlled cytoplasmic and nuclear localization of plasmid DNA and siRNA by differentially tailored polyethylenimine.

  Journal of controlled release : official journal of the Controlled Release Society 20090210

• Adaptative modifications of right coronary myocytes voltage-gated K+ currents in rat with hypoxic pulmonary hypertension.

  Pflugers Archiv : European journal of physiology 20090201

• Protein kinase A modulates A-type potassium currents of larval zebrafish (Danio rerio) white muscle fibres.

  Acta physiologica (Oxford, England) 20090201

• Histamine enhances voltage-gated potassium currents of ON bipolar cells in macaque retina.

  Investigative ophthalmology & visual science 20090201

• Characterization of ion channels in human preadipocytes.

  Journal of cellular physiology 20090201

• Isoflurane modulates excitability in the mouse thalamus via GABA-dependent and GABA-independent mechanisms.

  Neuropharmacology 20090201

• Blockade of voltage-sensitive K+ channels increases contractility more in transverse than in longitudinal rat detrusor strips.

  Urology 20090201

• Inhibitory effect of glutamate release from rat cerebrocortical nerve terminals by resveratrol.

  Neurochemistry international 20090201

• Enhanced hypoxia susceptibility in hippocampal slices from a mouse model of rett syndrome.

  Journal of neurophysiology 20090201

• Inhibition of Ca(2+)-dependent glutamate release from cerebral cortex synaptosomes of rats with experimental autoimmune encephalomyelitis.

  Journal of neurochemistry 20090201

• Pharmacokinetics of 14C-radioactivity after oral intake of a single dose of 14C-labeled fampridine (4-aminopyridine) in healthy volunteers.

  Clinical therapeutics 20090201

• Endothelium-independent vasodilation induced by kolaviron, a biflavonoid complex from Garcinia kola seeds, in rat superior mesenteric arteries.

  Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20090201

• Bis{(E)-3-[(diethyl-methyl-ammonio)meth-yl]-N-[3-(N,N-dimethyl-sulfamo-yl)-1-methyl-pyridin-4-yl-idene]-4-methoxy-anilinium} tetra-iodide penta-hydrate.

  Acta crystallographica. Section E, Structure reports online 20090201

• Endothelium-independent vasorelaxant effect of sodium ferulate on rat thoracic aorta.

  Life sciences 20090116

• Cyanocobalamin, vitamin B12, depresses glutamate release through inhibition of voltage-dependent Ca2+ influx in rat cerebrocortical nerve terminals (synaptosomes).

  European journal of pharmacology 20090114

• Synthesis and evaluation of dextran-budesonide conjugates as colon specific prodrugs for treatment of ulcerative colitis.

  International journal of pharmaceutics 20090105

• The role of potassium channels in the vasodilatory effect of caffeine in human internal mammary arteries.

  Vascular pharmacology 20090101

• Role of acid-sensing ion channel 3 in sub-acute-phase inflammation.

  Molecular pain 20090101

• [Treatment approach to congenital myasthenic syndrome in a patient with acetylcholine receptor deficiency].

  No to hattatsu = Brain and development 20090101

• The relaxation mechanisms of tetrandrine on the rabbit corpus cavernosum tissue in vitro.

  Natural product research 20090101

• Diminished presynaptic GABA(B) receptor function in the neocortex of a genetic model of absence epilepsy.

  Neuro-Signals 20090101

• [A case of Lambert-Eaton myasthenic syndrome with small cell lung cancer, treated with 3,4-diaminopyridine].

  Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20090101

• Diphenyl diselenide and diphenyl ditelluride increase the latency for 4-aminopyridine-induced chemical seizure and prevent death in mice.

  Acta biochimica Polonica 20090101

• In vitro study of the tocolytic effect of oroxylin A from Scutellaria baicalensis root.

  Journal of biomedical science 20090101

• Conduction failures in rabbit saphenous nerve unmyelinated fibers.

  Neuro-Signals 20090101

• Characterization of voltage-gated Ca(2+) conductances in layer 5 neocortical pyramidal neurons from rats.

  PloS one 20090101

• Chemically-induced RAT mesenchymal stem cells adopt molecular properties of neuronal-like cells but do not have basic neuronal functional properties.

  PloS one 20090101

• Why do taste cells generate action potentials?

  Journal of biology 20090101

• Role of potassium channels in the relaxant effect of levosimendan in guinea pig tracheal preparations.

  Pharmacological reports : PR 20090101

• Arylbenzazepines are potent modulators for the delayed rectifier K+ channel: a potential mechanism for their neuroprotective effects.

  PloS one 20090101

• Characterization of voltage-gated potassium channels in human neural progenitor cells.

  PloS one 20090101

• Glutamate release from astrocytic gliosomes under physiological and pathological conditions.

  International review of neurobiology 20090101

• [The influence of palladium containing new synthesized biological active substances to protein metabolism in organism].

  Georgian medical news 20090101

• Kv4 Channels Underlie the Subthreshold-Operating A-type K-current in Nociceptive Dorsal Root Ganglion Neurons.

  Frontiers in molecular neuroscience 20090101

• Enhancing m currents: a way out for neuropathic pain?

  Frontiers in molecular neuroscience 20090101

• Glutamate excitotoxicity inflicts paranodal myelin splitting and retraction.

  PloS one 20090101

• Predominant functional expression of Kv1.3 by activated microglia of the hippocampus after Status epilepticus.

  PloS one 20090101

• Characterisation of K+ currents in the C8-B4 microglial cell line and their regulation by microglia activating stimuli.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20090101

• Selective and irreversible inhibitors of mosquito acetylcholinesterases for controlling malaria and other mosquito-borne diseases.

  PloS one 20090101

• Ion channels to inactivate neurons in Drosophila.

  Frontiers in molecular neuroscience 20090101

• Characterization of multiple ion channels in cultured human cardiac fibroblasts.

  PloS one 20090101

• Effects of taurine on contractions of the porcine coronary artery.

  Pharmacological reports : PR 20090101

• Regulators involved in the electrically stimulated response of feline esophageal smooth muscle.

  Pharmacology 20090101

• Effects of protamine sulphate on spontaneous and calcium-induced contractile activity in the rat uterus are potassium channels-mediated.

  General physiology and biophysics 20090101

• Antinociceptive action of oxytocin involves inhibition of potassium channel currents in lamina II neurons of the rat spinal cord.

  Molecular pain 20090101

• Status epilepticus affects the gigantocellular network of the pontine reticular formation.

  BMC neuroscience 20090101

• Developmental expression of a functional TASK-1 2P domain K+ channel in embryonic chick heart.

  Journal of biomedical science 20090101

• Developmental expression of BK channels in chick cochlear hair cells.

  BMC developmental biology 20090101

• Neural progenitor cells attenuate inflammatory reactivity and neuronal loss in an animal model of inflamed AD brain.

  Journal of neuroinflammation 20090101

• A new photosensory function for simple photoreceptors, the intrinsically photoresponsive neurons of the sea slug onchidium.

  Frontiers in cellular neuroscience 20090101

• Distance-dependent homeostatic synaptic scaling mediated by a-type potassium channels.

  Frontiers in cellular neuroscience 20090101

• The symptomatic management of multiple sclerosis.

  Annals of Indian Academy of Neurology 20090101

• Rehabilitation challenges in multiple sclerosis.

  Annals of Indian Academy of Neurology 20090101

• Excitotoxic insults lead to peroxiredoxin hyperoxidation.

  Oxidative medicine and cellular longevity 20090101

• Neurokinin-1 receptor activation in globus pallidus.

  Frontiers in neuroscience 20090101

• Frequency-Domain Analysis of Intrinsic Neuronal Properties using High-Resistant Electrodes.

  Frontiers in neuroscience 20090101

• Altered expression of voltage-gated potassium channel 4.2 and voltage-gated potassium channel 4-interacting protein, and changes in intracellular calcium levels following lithium-pilocarpine-induced status epilepticus.

  Neuroscience 20081202

• ATP signalling in epilepsy.

  Purinergic signalling 20081201

• The minimum coronary artery diameter in which coronary spasm can be identified by synchrotron radiation coronary angiography.

  European journal of radiology 20081201

• Effects of taurine on aortic rings isolated from fructose-fed insulin resistance Sprague-Dawley rat are changed.

  Cardiovascular drugs and therapy 20081201

• [Pharmacotherapy of central oculomotor disorders].

  Der Nervenarzt 20081201

• Involvement of the cAMP-dependent pathway in the reduction of epileptiform bursting caused by somatostatin in the mouse hippocampus.

  Naunyn-Schmiedeberg's archives of pharmacology 20081201

• HSP70 expression protects against hippocampal neurodegeneration induced by endogenous glutamate in vivo.

  Neuropharmacology 20081201

• Reverse Na(+)/Ca(2+)-exchange mediated Ca(2+)-entry and noradrenaline release in Na(+)-loaded peripheral sympathetic nerves.

  Neurochemistry international 20081201

• Effects of exercise training and hypercholesterolemia on adenosine activation of voltage-dependent K+ channels in coronary arterioles.

  Journal of applied physiology (Bethesda, Md. : 1985) 20081201

• Long-lasting in vivo inotropic effects of the K(+) channel blocker 3,4-diaminopyridine during fatigue-inducing stimulation.

  Muscle & nerve 20081201

• K(+)-channel openers suppress epileptiform activities induced by 4-aminopyridine in cultured rat hippocampal neurons.

  Journal of pharmacological sciences 20081201

• [Influence of 4-aminopyridine on human ovarian luteinized granulosa cell proliferation, production, and apoptosis through inhibiting voltage-gated K+ channel].

  Zhonghua fu chan ke za zhi 20081201

• 2-Nitro-N-(4-pyridinio)benzene-sulfonamidate monohydrate.

  Acta crystallographica. Section E, Structure reports online 20081201

• 4-(4-Nitro-benzene-sulfonamido)pyridinium bromide.

  Acta crystallographica. Section E, Structure reports online 20081201

• Bis[4-(2-nitro-benzene-sulfonamido)-pyridinium] hexa-fluoro-silicate.

  Acta crystallographica. Section E, Structure reports online 20081201

• 4-(4-Nitro-benzene-sulfonamido)pyridinium nitrate.

  Acta crystallographica. Section E, Structure reports online 20081201

• 4-aminopyridine toxicity with unintentional overdose in four patients with multiple sclerosis.

  Neurology 20081125

• Spectroscopic and structural elucidation of 4-dimethylaminopyridine and its hydrogensquarate.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20081115

• The mode of death of epilepsy-induced 'dark' neurons is neither necrosis nor apoptosis: an electron-microscopic study.

  Brain research 20081106

• Decreased connexin43 expression in the mouse heart potentiates pacing-induced remodeling of repolarizing currents.

  American journal of physiology. Heart and circulatory physiology 20081101

• Repolarization abnormalities and afterdepolarizations in a canine model of sudden cardiac death.

  American journal of physiology. Regulatory, integrative and comparative physiology 20081101

• Mechanisms mediating the oxygen-induced vasoreactivity of the ductus arteriosus in the chicken embryo.

  American journal of physiology. Regulatory, integrative and comparative physiology 20081101

• Conductances mediating intrinsic theta-frequency membrane potential oscillations in layer II parasubicular neurons.

  Journal of neurophysiology 20081101

• Comparison of acute, chronic and post-treatment effects of carbamazepine and vinpocetine on hearing loss and seizures induced by 4-aminopyridine.

  Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 20081101

• The effects of oxaliplatin, an anticancer drug, on potassium channels of the peripheral myelinated nerve fibres of the adult rat.

  Neurotoxicology 20081101

• HDT-1, a new synthetic compound, inhibits glutamate release in rat cerebral cortex nerve terminals (synaptosomes).

  Acta pharmacologica Sinica 20081101

• Mechanisms underlying pioglitazone-mediated relaxation in isolated blood vessel.

  Journal of pharmacological sciences 20081101

• (4-Aminopyridine-kappaN1)(phthalocyaninato-kappa4N)zinc(II) tetrahydrofuran disolvate.

  Acta crystallographica. Section C, Crystal structure communications 20081101

• A PI3-kinase-mediated negative feedback regulates neuronal excitability.

  PLoS genetics 20081101

• Activity-dependent regulation of the dopamine transporter is mediated by Ca(2+)/calmodulin-dependent protein kinase signaling.

  The European journal of neuroscience 20081101

• Octa-akis(4-amino-pyridine)-1κN,2κN-aqua-2κO-μ-carbonato-1:2κO,O':O''-dinickel(II) dichloride penta-hydrate.

  Acta crystallographica. Section E, Structure reports online 20081101

• 4-(4-Nitro-benzene-sulfonamido)pyri-dinium chloride.

  Acta crystallographica. Section E, Structure reports online 20081101

• 4-Nitro-N-(4-pyridinio)benzene-sulfonamidate monohydrate.

  Acta crystallographica. Section E, Structure reports online 20081101

• Dynamic, nonlinear feedback regulation of slow pacemaking by A-type potassium current in ventral tegmental area neurons.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20081022

• Fampridine for MS responders: clinically relevant or hypothesis generating?

  Neurology 20081007

• Dose comparison trial of sustained-release fampridine in multiple sclerosis.

  Neurology 20081007

• Functional brain imaging of peripheral and central vestibular disorders.

  Brain : a journal of neurology 20081001

• Comparative effects of tramadol on vascular reactivity in normotensive and spontaneously hypertensive rats.

  Clinical and experimental pharmacology & physiology 20081001

• Low-voltage-activated potassium channels underlie the regulation of intrinsic firing properties of rat vestibular ganglion cells.

  Journal of neurophysiology 20081001

• Protein-ligand interaction prediction: an improved chemogenomics approach.

  Bioinformatics (Oxford, England) 20081001

• p75 neurotrophin receptor regulates agonist-induced pulmonary vasoconstriction.

  American journal of physiology. Heart and circulatory physiology 20081001

• K+ channel inhibition modulates the biochemical and morphological differentiation of human placental cytotrophoblast cells in vitro.

  American journal of physiology. Regulatory, integrative and comparative physiology 20081001

• Sustained-release fampridine for symptomatic treatment of multiple sclerosis.

  The Annals of pharmacotherapy 20081001

• Vasorelaxant effect of a self-etch adhesive system through calcium antagonistic action.

  Journal of endodontics 20081001

• Rhythmic discharge induced by temperature variation and drugs in isolated sympathetic ganglia.

  Clinical and experimental hypertension (New York, N.Y. : 1993) 20081001

• 4-Amino-pyridinium 4-nitro-benzoate 4-nitro-benzoic acid.

  Acta crystallographica. Section E, Structure reports online 20081001

• Testosterone deprivation by castration impairs expression of voltage-dependent potassium channels in rat aorta.

  European journal of pharmacology 20080928

• Role of voltage-dependent potassium channels and myo-endothelial gap junctions in 4-aminopyridine-induced inhibition of acetylcholine relaxation in rat carotid artery.

  European journal of pharmacology 20080904

• Generalization of seizures parallels the formation of 'dark' neurons in the hippocampus and pontine reticular formation after focal-cortical application of 4-aminopyridine (4-AP) in the rat.

  Brain research 20080904

• Sulfonylurea receptor-dependent and -independent pathways mediate vasodilation induced by ATP-sensitive K+ channel openers.

  Molecular pharmacology 20080901

• K+ channels and the cAMP-PKA pathway modulate TGF-beta1-induced migration of rat vascular myofibroblasts.

  Journal of cellular physiology 20080901

• On the role of calcium and potassium currents in circadian modulation of firing rate in rat suprachiasmatic nucleus neurons: multielectrode dish analysis.

  Neuroscience research 20080901

• Mechanisms of hyperthermia-induced depression of GABAergic synaptic transmission in the immature rat hippocampus.

  Journal of neurochemistry 20080901

• Can inhibition of IKur promote atrial fibrillation?

  Heart rhythm 20080901

• [Study on intermolecular interaction between 4-aminopyridine and methacrylic acid using two dimensional FTIR spectroscopy].

  Guang pu xue yu guang pu fen xi = Guang pu 20080901

• mGlu5 receptor deletion does not confer seizure protection to mice.

  Life sciences 20080829

• Vitamin B2 inhibits glutamate release from rat cerebrocortical nerve terminals.

  Neuroreport 20080827

• An analytical flow injection system to measure glutamate in microdialysis samples based on an enzymatic reaction and electrochemical detection.

  Neurochemical research 20080801

• Layer-specific generation and propagation of seizures in slices of developing neocortex: role of excitatory GABAergic synapses.

  Journal of neurophysiology 20080801

• Experimental diabetes enhances Ca2+ mobilization and glutamate exocytosis in cerebral synaptosomes from mice.

  Diabetes research and clinical practice 20080801

• Calcitonin gene-related peptide inhibits angiotensin II-mediated vasoconstriction in human radial arteries: role of the Kir channel.

  The Journal of thoracic and cardiovascular surgery 20080801

• Characterization of ionic currents in human neural stem cells.

  The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 20080801

• Tetraethylammonium (TEA) increases the inactivation time constant of the transient K+ current in suprachiasmatic nucleus neurons.

  Brain research 20080724

• Mechanism of ligand photodissociation in photoactivable [Ru(bpy)2L2]2+ complexes: a density functional theory study.

  Journal of the American Chemical Society 20080723

• Pre- and post-synaptic mechanisms of synaptic strength homeostasis revealed by slowpoke and shaker K+ channel mutations in Drosophila.

  Neuroscience 20080717

• Potassium channel blocker 4-aminopyridine is effective in interictal cerebellar symptoms in episodic ataxia type 2--a video case report.

  Movement disorders : official journal of the Movement Disorder Society 20080715

• Ruthenium porphyrin functionalized single-walled carbon nanotube arrays--a step toward light harvesting antenna and multibit information storage.

  Journal of the American Chemical Society 20080709

• Spontaneous activity in Purkinje cells: multi-electrode recording from organotypic cerebellar slice cultures.

  Brain research 20080707

• Postnatal inflammation increases seizure susceptibility in adult rats.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20080702

• Effects of the muscarinic agonist, 5-methylfurmethiodide, on contraction and electrophysiology of Ascaris suum muscle.

  International journal for parasitology 20080701

• Functional and molecular identification of pH-sensitive K+ channels in murine urinary bladder smooth muscle.

  BJU international 20080701

• Partial inhibition of complex I activity increases Ca-independent glutamate release rates from depolarized synaptosomes.

  Journal of neurochemistry 20080701

• Mitochondria-dependent regulation of Kv currents in rat pulmonary artery smooth muscle cells.

  American journal of physiology. Lung cellular and molecular physiology 20080701

• Kaempferol stimulates large conductance Ca2+ -activated K+ (BKCa) channels in human umbilical vein endothelial cells via a cAMP/PKA-dependent pathway.

  British journal of pharmacology 20080701

• Potassium channel contributions to afferent arteriolar tone in normal and diabetic rat kidney.

  American journal of physiology. Renal physiology 20080701

• Effects of subtype-selective group I mGluR antagonists on synchronous activity induced by 4-aminopyridine/CGP 55845 in adult guinea pig hippocampal slices.

  Neuropharmacology 20080701

• Niflumic acid hyperpolarizes smooth muscle cells via calcium-activated potassium channel in spiral modiolar artery of guinea pigs.

  Acta pharmacologica Sinica 20080701

• Detection of IUPAC and IUPAC-like chemical names.

  Bioinformatics (Oxford, England) 20080701

• Unmodified CdSe quantum dots induce elevation of cytoplasmic calcium levels and impairment of functional properties of sodium channels in rat primary cultured hippocampal neurons.

  Environmental health perspectives 20080701

• A reduction in the amount and anti-contractile effect of periadventitial mesenteric adipose tissue precedes hypertension development in spontaneously hypertensive rats.

  Hypertension research : official journal of the Japanese Society of Hypertension 20080701

• Tetra-kis(4-amino-pyridine-κN)dichlorido-copper(II) monohydrate.

  Acta crystallographica. Section E, Structure reports online 20080701

• Chemiluminescent detection systems of horseradish peroxidase employing nucleophilic acylation catalysts.

  Analytical biochemistry 20080615

• A glue-based, screw-free method for implantation of intra-cranial electrodes in young mice.

  Journal of neuroscience methods 20080615

• Single-channel properties of I K,slow1 and I K,slow2 in mouse ventricular myocytes.

  Pflugers Archiv : European journal of physiology 20080601

• The use of FTIR and NMR spectroscopies to study prepolymerisation interactions in nitrogen heterocycles.

  Analytical and bioanalytical chemistry 20080601

• Mechanisms of neuromodulation as dissected using Sr2+ at motor nerve endings.

  Journal of neurophysiology 20080601

• Electrophysiological properties and gap junction coupling of striatal astrocytes.

  Neurochemistry international 20080601

• In vivo imaging of seizure activity in a novel developmental seizure model.

  Experimental neurology 20080601

• Standard antiepileptic drugs fail to block epileptiform activity in rat organotypic hippocampal slice cultures.

  British journal of pharmacology 20080601

• Differential cholinergic modulation of Ca2+ transients evoked by backpropagating action potentials in apical and basal dendrites of cortical pyramidal neurons.

  Journal of neurophysiology 20080601

• Cellular bases for human atrial fibrillation.

  Heart rhythm 20080601

• The therapeutic effects of Rho-ROCK inhibitors on CNS disorders.

  Therapeutics and clinical risk management 20080601

• Water and ion channels: crucial in the initiation and progression of apoptosis in central nervous system?

  Current neuropharmacology 20080601

• Rapid effects of 1alpha,25(OH)2D3 in resting human peripheral blood mononuclear cells.

  European journal of pharmacology 20080531

• 5-HT1A receptor-mediated activation of a G-protein-coupled inwardly rectifying K+ current in rat medial preoptic area neurons.

  European journal of pharmacology 20080531

• Iberiotoxin-sensitive large conductance Ca2+ -dependent K+ (BK) channels regulate the spike configuration in the burst firing of cerebellar Purkinje neurons.

  Brain research 20080530

• Neuronal proto-oncogene expression in the pharmacological assessment of the synaptic mechanisms of the hippocampus in rats.

  Ideggyogyaszati szemle 20080530

• Estradiol modulation of phenylephrine-induced excitatory responses in ventromedial hypothalamic neurons of female rats.

  Proceedings of the National Academy of Sciences of the United States of America 20080520

• Drug assessment based on detection of L-glutamate released from C6 glioma cells using an enzyme-luminescence method.

  Analytical chemistry 20080515

• The role of Akt-GSK-3beta signaling and synaptic strength in phencyclidine-induced neurodegeneration.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20080501

• Kv1 and Kir2 potassium channels are expressed in rat brain endothelial cells.

  Pflugers Archiv : European journal of physiology 20080501

• Facilitatory effect of glutamate exocytosis from rat cerebrocortical nerve terminals by alpha-tocopherol, a major vitamin E component.

  Neurochemistry international 20080501

• Antiepileptic activity of zonisamide on hippocampal CA3 neurons does not depend on carbonic anhydrase inhibition.

  Epilepsy research 20080501

• Voltage-dependent K+ channels regulate the duration of reactive hyperemia in the canine coronary circulation.

  American journal of physiology. Heart and circulatory physiology 20080501

• NKCC1 and KCC2 prevent hyperexcitability in the mouse hippocampus.

  Epilepsy research 20080501

• Microtubule-associated protein 2-positive cells derived from microglia possess properties of functional neurons.

  Biochemical and biophysical research communications 20080418

• Glycinergic synaptic currents in the deep cerebellar nuclei.

  Neuropharmacology 20080401

• Subthreshold sodium current underlies essential functional specializations at primary auditory afferents.

  Journal of neurophysiology 20080401

• The anchoring protein SAP97 retains Kv1.5 channels in the plasma membrane of cardiac myocytes.

  American journal of physiology. Heart and circulatory physiology 20080401

• 4-Aminopyridine-sensitive outward currents in preBötzinger complex neurons influence respiratory rhythm generation in neonatal mice.

  The Journal of physiology 20080401

• Mouse N-acetyltransferase type 2, the homologue of human N-acetyltransferase type 1.

  Biochemical pharmacology 20080401

• 2-hydroxyoleic acid affects cardiomyocyte [Ca2+]i transient and contractility in a region-dependent manner.

  American journal of physiology. Heart and circulatory physiology 20080401

• The cyclooxygenase-2/prostaglandin E2 pathway is involved in the somatostatin-induced decrease of epileptiform bursting in the mouse hippocampus.

  Neuropharmacology 20080401

• A study on the inhibition of adenosine deaminase.

  Journal of enzyme inhibition and medicinal chemistry 20080401

• The characteristics of action potential and nonselective cation current of cardiomyocytes in rabbit superior vena cava.

  Science in China. Series C, Life sciences 20080401

• Testosterone relaxes rabbit seminal vesicle by calcium channel inhibition.

  The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 20080401

• 4-Amino-pyridinium 4-amino-benzene-sulfonate 4-ammonio-benzene-sulfonate monohydrate.

  Acta crystallographica. Section E, Structure reports online 20080401

• Kvbeta1.1 associates with Kvalpha1.4 in Chinese hamster ovary cells and pigeon type II vestibular hair cells and enhances the amplitude, inactivation and negatively shifts the steady-state inactivation range.

  Neuroscience 20080327

• Preparation and characterization of polyelectrolyte-coated gold nanoparticles.

  Langmuir : the ACS journal of surfaces and colloids 20080318

• Licking for taste solutions by potassium-deprived rats: specificity and mechanisms.

  Physiology & behavior 20080318

• Diminished A-type potassium current and altered firing properties in presympathetic PVN neurones in renovascular hypertensive rats.

  The Journal of physiology 20080315

• Pre- and postsynaptic plasticity underlying augmented glutamatergic inputs to hypothalamic presympathetic neurons in spontaneously hypertensive rats.

  The Journal of physiology 20080315

• Effects of 4-aminopyridine on sharp wave-ripples in rat hippocampal slices.

  Neuroreport 20080305

• Characterization of the slowly inactivating sodium current INa2 in canine cardiac single Purkinje cells.

  Experimental physiology 20080301

• Maturation of the contractile response of the Emu ductus arteriosus.

  Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20080301

• Role of neuronal voltage-gated K(+) channels in the modulation of the nitrergic neurotransmission of the pig urinary bladder neck.

  British journal of pharmacology 20080301

• Kv4 (A-type) potassium currents in the mouse medial nucleus of the trapezoid body.

  The European journal of neuroscience 20080301

• Studies of the lauroylation of wheat straw hemicelluloses under heating.

  Journal of agricultural and food chemistry 20080227

• Sequence dependence of methylation rate enhancement in meta-phenyleneethynylene foldamers.

  Chemical communications (Cambridge, England) 20080227

• Simultaneous glutamate and EEG activity measurements during seizures in rat hippocampal region with the use of an electrochemical biosensor.

  Journal of neuroscience methods 20080215

• Vasorelaxant effect of taurine is diminished by tetraethylammonium in rat isolated arteries.

  European journal of pharmacology 20080202

• Differential effects of isoflurane on A-type and delayed rectifier K channels in rat substantia nigra.

  European journal of pharmacology 20080202

• Transition between two excitabilities in mesencephalic V neurons.

  Journal of computational neuroscience 20080201

• Antagonistic effects of atipamezole, flumazenil and 4-aminopyridine against anaesthesia with medetomidine, midazolam and ketamine combination in cats.

  Journal of feline medicine and surgery 20080201

• Mechanism of guanosine-induced neuroprotection in rat hippocampal slices submitted to oxygen-glucose deprivation.

  Neurochemistry international 20080201

• Vesicular release of glutamate from hippocampal neurons in culture: an immunocytochemical assay.

  Experimental brain research 20080201

• Reduced ictogenic potential of 4-aminopyridine in the perirhinal and entorhinal cortex of kainate-treated chronic epileptic rats.

  Neurobiology of disease 20080201

• Currents contributing to decision making in neurons B31/B32 of Aplysia.

  Journal of neurophysiology 20080201

• B chain is a functional subunit of beta-bungarotoxin for inducing apoptotic death of human neuroblastoma SK-N-SH cells.

  Toxicon : official journal of the International Society on Toxinology 20080201

• Neonatal rat cardiac fibroblasts express three types of voltage-gated K+ channels: regulation of a transient outward current by protein kinase C.

  American journal of physiology. Heart and circulatory physiology 20080201

• Clinical studies in spinal cord injury: moving towards successful trials.

  British journal of neurosurgery 20080201

• Sildenafil inhibits duodenal contractility via activation of the NO-K+ channel pathway.

  Fundamental & clinical pharmacology 20080201

• Mechanisms underlying the vasorelaxant effect induced by proanthocyanidin-rich fraction from Croton celtidifolius in rat small resistance arteries.

  Journal of pharmacological sciences 20080201

• 9-(Dimethoxy-meth-yl)anthracene.

  Acta crystallographica. Section E, Structure reports online 20080201

• Vasorelaxant effect of isopropyl 3-(3, 4-dihydroxyphenyl)-2-hydroxypropanoate, a novel metabolite from Salvia miltiorrhiza, on isolated rat mesenteric artery.

  European journal of pharmacology 20080128

• Ginsenosides Rg1 and Rb1 enhance glutamate release through activation of protein kinase A in rat cerebrocortical nerve terminals (synaptosomes).

  European journal of pharmacology 20080106

• Antiepileptic effect of carbenoxolone on seizures induced by 4-aminopyridine: a study in the rat hippocampus and entorhinal cortex.

  Brain research 20080102

• Mechanisms of the vasorelaxant effect of 1, 5-dihydroxy-2, 3-dimethoxy-xanthone, an active metabolite of 1-hydroxy-2, 3, 5-trimethoxy-xanthone isolated from a Tibetan herb, Halenia elliptica, on rat coronary artery.

  Life sciences 20080102

• Leptin inhibits 4-aminopyridine- and pentylenetetrazole-induced seizures and AMPAR-mediated synaptic transmission in rodents.

  The Journal of clinical investigation 20080102

• Anticonvulsant effects of leptin in epilepsy.

  The Journal of clinical investigation 20080102

• Role of the cyclic-AMP/PKA cascade and of P/Q-type Ca++ channels in endocannabinoid-mediated long-term depression in the nucleus accumbens.

  Neuropharmacology 20080101

• Characterization of the effects of ryanodine, TTX, E-4031 and 4-AP on the sinoatrial and atrioventricular nodes.

  Progress in biophysics and molecular biology 20080101

• Inotropic effects of the K+ channel blocker 3,4-diaminopyridine on fatigued diaphragm muscle.

  Respiratory physiology & neurobiology 20080101

• Involvement of voltage-gated K+ and Na+ channels in gastric epithelial cell migration.

  Molecular and cellular biochemistry 20080101

• Characterization of agonist-induced vasoconstriction in mouse pulmonary artery.

  American journal of physiology. Heart and circulatory physiology 20080101

• Decreased function of voltage-gated potassium channels contributes to augmented myogenic tone of uterine arteries in late pregnancy.

  American journal of physiology. Heart and circulatory physiology 20080101

• 4-Aminopyridine derivatives with anticholinesterase and antiamnesic activity.

  Bioorganic & medicinal chemistry letters 20080101

• Potassium channels are involved in testosterone-induced vasorelaxation of human umbilical artery.

  Naunyn-Schmiedeberg's archives of pharmacology 20080101

• Blockade of AMPA-receptors attenuates 4-aminopyridine seizures, decreases the activation of inhibitory neurons but is ineffective against seizure-related astrocytic swelling.

  Epilepsy research 20080101

• A quantitative method to assess extrasynaptic NMDA receptor function in the protective effect of synaptic activity against neurotoxicity.

  BMC neuroscience 20080101

• Functional and pharmacological characterization of a Shal-related K+ channel subunit in Zebrafish.

  BMC physiology 20080101

• Delayed rectifier and A-type potassium channels associated with Kv 2.1 and Kv 4.3 expression in embryonic rat neural progenitor cells.

  PloS one 20080101

• [Lambert-Eaton Myasthenic Syndrome associated with vocal cord carcinoma].

  Revue neurologique 20080101

• Late expression of FosB transcription factor in 4-aminopyridine-induced seizures in the rat cerebral cortex.

  Acta histochemica 20080101

• New highly asymmetric Henry reaction catalyzed by Cu(II) and a C(1)-symmetric aminopyridine ligand, and its application to the synthesis of miconazole.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20080101

• Molecular and cellular limits to somatosensory specificity.

  Molecular pain 20080101

• Monomer versus alcohol activation in the 4-dimethylaminopyridine-catalyzed ring-opening polymerization of lactide and lactic O-carboxylic anhydride.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20080101

• Differentiation of human embryonic stem cells to regional specific neural precursors in chemically defined medium conditions.

  PloS one 20080101

• Effects of active conductance distribution over dendrites on the synaptic integration in an identified nonspiking interneuron.

  PloS one 20080101

• Neurotherapeutics in multiple sclerosis: novel agents and emerging treatment strategies.

  The Mount Sinai journal of medicine, New York 20080101

• L-type Ca2+ channel function is linked to dystrophin expression in mammalian muscle.

  PloS one 20080101

• A naturally occurring omega current in a Kv3 family potassium channel from a platyhelminth.

  BMC neuroscience 20080101

• Probing the dynamics of identified neurons with a data-driven modeling approach.

  PloS one 20080101

• Mobilisation of stored calcium in the neck region of human sperm--a mechanism for regulation of flagellar activity.

  The International journal of developmental biology 20080101

• Modelling drug modulation of nystagmus.

  Progress in brain research 20080101

• Aminopyridines for the treatment of cerebellar and ocular motor disorders.

  Progress in brain research 20080101

• Upregulated H-current in hyperexcitable CA1 dendrites after febrile seizures.

  Frontiers in cellular neuroscience 20080101

• Dendritic backpropagation and synaptic plasticity in the mormyrid electrosensory lobe.

  Journal of physiology, Paris 20080101

• Fatigue characteristics in multiple sclerosis: the North American Research Committee on Multiple Sclerosis (NARCOMS) survey.

  Health and quality of life outcomes 20080101

• 4-aminopyridine-induced contracture in frog ventricle is due to calcium released from intracellular stores.

  Indian journal of physiology and pharmacology 20080101

• 2-Nitro-N-(4-pyridinio)benzene-sulfonamidate.

  Acta crystallographica. Section E, Structure reports online 20080101

• Long-lasting dephosphorylation of connexin 43 in acute seizures is regulated by NMDA receptors in the rat cerebral cortex.

  Molecular medicine reports 20080101

• Preparation and characterization of 4-dimethylaminopyridine-stabilized palladium nanoparticles.

  Langmuir : the ACS journal of surfaces and colloids 20071204

• Role of K(+) channels in the regulation of electrical spontaneous activity of the mouse small intestine.

  Pflugers Archiv : European journal of physiology 20071201

• A fast transient outward current in layer II/III neurons of rat perirhinal cortex.

  Pflugers Archiv : European journal of physiology 20071201

• Long-lasting plasma membrane permeabilization in mammalian cells by nanosecond pulsed electric field (nsPEF).

  Bioelectromagnetics 20071201

• 4-Aminopyridine (fampridine) effectively treats amlodipine poisoning: a case report.

  Journal of clinical pharmacy and therapeutics 20071201

• Epileptiform synchronization in the rat insular and perirhinal cortices in vitro.

  The European journal of neuroscience 20071201

• KCNA1 and TRPC6 ion channels and NHE1 exchanger operate the biological outcome of HGF/scatter factor in renal tubular cells.

  Growth factors (Chur, Switzerland) 20071201

• Emerging synergisms between drugs and physiologically-patterned weak magnetic fields: implications for neuropharmacology and the human population in the twenty-first century.

  Current neuropharmacology 20071201

• Visceral afferents directly activate catecholamine neurons in the solitary tract nucleus.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20071128

• (-)-Epigallocatechin gallate, the most active polyphenolic catechin in green tea, presynaptically facilitates Ca2+-dependent glutamate release via activation of protein kinase C in rat cerebral cortex.

  Synapse (New York, N.Y.) 20071101

• Pharmacological characterization and molecular determinants of the activation of transient receptor potential V2 channel orthologs by 2-aminoethoxydiphenyl borate.

  Molecular pharmacology 20071101

• Electrophysiological properties of human adipose tissue-derived stem cells.

  American journal of physiology. Cell physiology 20071101

• The plateau outward current in canine ventricle, sensitive to 4-aminopyridine, is a constitutive contributor to ventricular repolarization.

  British journal of pharmacology 20071101

• Effects of ralfinamide, a Na+ channel blocker, on firing properties of nociceptive dorsal root ganglion neurons of adult rats.

  Experimental neurology 20071101

• Is there a functional correlate of Kv1.5 in the ventricle of canine heart and what would it mean for the use of I(Kur) blockers?

  British journal of pharmacology 20071101

• Adult astroglia is competent for Na+/Ca2+ exchanger-operated exocytotic glutamate release triggered by mild depolarization.

  Journal of neurochemistry 20071101

• Effects of K+ channel modulators on oscillatory contractions in sinoaortic denervated rat aortas.

  Biological & pharmaceutical bulletin 20071101

• Distinct mammalian precursors are committed to generate neurons with defined dendritic projection patterns.

  PLoS biology 20071101

• Acetaldehyde mediates alcohol activation of the mesolimbic dopamine system.

  The European journal of neuroscience 20071101

• Evoked membrane potential change in rat optic nerve fiber: computer simulation.

  Neuroscience bulletin 20071101

• Adenosine A1 but not A2a receptor agonist reduces hyperalgesia caused by a surgical incision in rats: a pertussis toxin-sensitive G protein-dependent process.

  Anesthesiology 20071101

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20071101

• Role of 4-aminopyridine-sensitive potassium channels in peripheral antinociception.

  European journal of pharmacology 20071031

• Kv1.1/1.2 channels are downstream effectors of nitric oxide on synaptic GABA release to preautonomic neurons in the paraventricular nucleus.

  Neuroscience 20071026

• State-dependent enhancement of subthreshold A-type potassium current by 4-aminopyridine in tuberomammillary nucleus neurons.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20071003

• Heat shock proteins and p53 play a critical role in K+ channel-mediated tumor cell proliferation and apoptosis.

  Apoptosis : an international journal on programmed cell death 20071001

• Potentiation phase of spike timing-dependent neuromodulation by a serotonergic interneuron involves an increase in the fraction of transmitter release.

  Journal of neurophysiology 20071001

• Zn(2+) slows down Ca(V)3.3 gating kinetics: implications for thalamocortical activity.

  Journal of neurophysiology 20071001

• The gender differences in the relaxation to levosimendan of human internal mammary artery.

  Cardiovascular drugs and therapy 20071001

• 4-Aminopyridine restores impaired hypoxic pulmonary vasoconstriction in endotoxemic mice.

  Anesthesiology 20071001

• Somatostatin inhibits the excitability of rat small-diameter trigeminal ganglion neurons that innervate nasal mucosa and project to the upper cervical dorsal horn via activation of somatostatin 2a receptor.

  Neuroscience 20070907

• Influence of sex, high-fat diet, and exercise training on potassium currents of swine coronary smooth muscle.

  American journal of physiology. Heart and circulatory physiology 20070901

• Temporal variability of repolarization in rat ventricular myocytes paced with time-varying frequencies.

  Experimental physiology 20070901

• Functional characterization of voltage-gated K+ channels in mouse pulmonary artery smooth muscle cells.

  American journal of physiology. Cell physiology 20070901

• Adiponectin is a novel humoral vasodilator.

  Cardiovascular research 20070901

• 4-aminopyridine restores vertical and horizontal neural integrator function in downbeat nystagmus.

  Brain : a journal of neurology 20070901

• Mechanisms of the vasorelaxant effect of 1-hydroxy-2, 3, 5-trimethoxy-xanthone, isolated from a Tibetan herb, Halenia elliptica, on rat coronary artery.

  Life sciences 20070901

• Time-dependent alteration in cromakalim-induced relaxation of corpus cavernosum from streptozocin-induced diabetic rats.

  Life sciences 20070901

• Heterogeneous composition of voltage-dependent K(+) currents in hepatic stellate cells.

  Yonsei medical journal 20070831

• Synaptic adhesion molecule OBCAM; synaptogenesis and dynamic internalization.

  Brain research 20070824

• Axon initial segment Kv1 channels control axonal action potential waveform and synaptic efficacy.

  Neuron 20070816

• Role of ERK1/2 signaling pathways in 4-aminopyridine-induced rat pulmonary vasoconstriction.

  European journal of pharmacology 20070813

• 4-Aminopyridine derivatives enhance impulse conduction in guinea-pig spinal cord following traumatic injury.

  Neuroscience 20070810

• [Successful treatment of a Lambert-Eaton myasthenic syndrome patient with 3,4-diaminopyridine].

  Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20070810

• The effect of zinc on glycinergic inhibitory postsynaptic currents in rat spinal dorsal horn neurons.

  Brain research 20070803

• Beneficial effects of 3,4-diaminopyridine on positioning downbeat nystagmus in a circumscribed uvulo-nodular lesion.

  Journal of neurology 20070801

• Beta1 (KCNMB1) subunits mediate lithocholate activation of large-conductance Ca2+-activated K+ channels and dilation in small, resistance-size arteries.

  Molecular pharmacology 20070801

• Area-specific resonance of excitatory networks in neocortex: control by outward currents.

  Epilepsia 20070801

• Membrane cholesterol modulates Kv1.5 potassium channel distribution and function in rat cardiomyocytes.

  The Journal of physiology 20070801

• Functional expression of ion channels in mesenchymal stem cells derived from umbilical cord vein.

  Stem cells (Dayton, Ohio) 20070801

• Differential expression of intrinsic membrane currents in defined cell types of the anterolateral bed nucleus of the stria terminalis.

  Journal of neurophysiology 20070801

• Models wagging the dog: are circuits constructed with disparate parameters?

  Neural computation 20070801

• Blockade of gap junction coupling by glycyrrhetinic acids in guinea pig cochlear artery: a whole-cell voltage- and current-clamp study.

  British journal of pharmacology 20070801

• The effect of hydrogen peroxide in human internal thoracic arteries: role of potassium channels, nitric oxide and cyclooxygenase products.

  Cardiovascular drugs and therapy 20070801

• Concatemers of brain Kv1 channel alpha subunits that give similar K+ currents yield pharmacologically distinguishable heteromers.

  Neuropharmacology 20070801

• In vivo assessment of safety and mechanisms underlying in vitro relaxation induced by Mikania laevigata Schultz Bip. ex Baker in the rat trachea.

  Journal of ethnopharmacology 20070725

• The role of small-conductance Ca2+-activated K+ channels in the modulation of 4-aminopyridine-induced burst firing in rat cerebellar Purkinje cells.

  Brain research 20070702

• Studies on some salicylaldehyde Schiff base derivatives and their complexes with Cr(III), Mn(II), Fe(III), Ni(II) and Cu(II).

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20070701

• Myasthenia gravis and Lambert-Eaton myasthenic syndrome in the same patient.

  Muscle & nerve 20070701

• Action potential clamp fingerprints of K+ currents in canine cardiomyocytes: their role in ventricular repolarization.

  Acta physiologica (Oxford, England) 20070701

• Detection of potassium currents and regulation of multidrug resistance by potassium channels in human gastric cancer cells.

  Cell biology international 20070701

• Cardiovascular effects of the aqueous extract from Caesalpinia ferrea: involvement of ATP-sensitive potassium channels.

  Vascular pharmacology 20070701

• Molecular expression and pharmacological identification of a role for K(v)7 channels in murine vascular reactivity.

  British journal of pharmacology 20070701

• K+ channel modulation of slow wave activity in the guinea-pig prostate.

  British journal of pharmacology 20070701

• Electrophysiologic mechanism underlying action potential prolongation by sevoflurane in rat ventricular myocytes.

  Anesthesiology 20070701

• Bis(4-aminopyridinium) hexachloridostannate(IV) and bis(p-toluidinium) hexachloridostannate(IV).

  Acta crystallographica. Section C, Crystal structure communications 20070701

• Therapeutic potential of neuronal two-pore domain potassium-channel modulators.

  Current opinion in investigational drugs (London, England : 2000) 20070701

• Survival of Swiss-Webster mouse cerebellar granule neurons is promoted by a combination of potassium channel blockers.

  Toxicology letters 20070615

• The functional difference between transient and sustained K+ currents on the action potentials in tetrodotoxin-resistant adult rat trigeminal ganglion neurons.

  Brain research 20070604

• Activators of the PKA and PKG pathways attenuate RhoA-mediated suppression of the KDR current in cerebral arteries.

  American journal of physiology. Heart and circulatory physiology 20070601

• Potassium initiates vasodilatation induced by a single skeletal muscle contraction in hamster cremaster muscle.

  The Journal of physiology 20070601

• Caffeine facilitation of glutamate release from rat cerebral cortex nerve terminals (synaptosomes) through activation protein kinase C pathway: an interaction with presynaptic adenosine A1 receptors.

  Synapse (New York, N.Y.) 20070601

• Inhibition of KATP channels in the rat tail artery by neurally released noradrenaline acting on postjunctional alpha2-adrenoceptors.

  The Journal of physiology 20070601

• Pituitary adenylate cyclase-activating polypeptide (PACAP) stimulates the oxygen sensing type I (glomus) cells of rat carotid bodies via reduction of a background TASK-like K+ current.

  Journal of neurochemistry 20070601

• Responses of the human submandibular artery to ACh and VIP.

  Journal of dental research 20070601

• Effects of long-term 4-aminopyridine therapy on glucose tolerance and glucokinetics in patients with spinal cord injury.

  Pharmacotherapy 20070601

• Donepezil in Alzheimer's disease: From conventional trials to pharmacogenetics.

  Neuropsychiatric disease and treatment 20070601

• Codeine presynaptically inhibits the glutamatergic synaptic transmission in the nucleus tractus solitarius of the guinea pig.

  Neuroscience 20070525

• Somatostatinergic modulation of firing pattern and calcium-activated potassium currents in medium spiny neostriatal neurons.

  Neuroscience 20070511

• Involvement of a Go-type G-protein coupled to guanylate cyclase in the phototransduction cGMP cascade of molluscan simple photoreceptors.

  Brain research 20070504

• Molecular and functional characterization of Kv4.2 and KChIP2 expressed in the porcine left ventricle.

  Pflugers Archiv : European journal of physiology 20070501

• The role of NO-cGMP pathway and potassium channels on the relaxation induced by clonidine in the rat mesenteric arterial bed.

  Vascular pharmacology 20070501

• Function of Kv1.5 channels and genetic variations of KCNA5 in patients with idiopathic pulmonary arterial hypertension.

  American journal of physiology. Cell physiology 20070501

• Signaling mechanisms of angiotensin II-induced attenuation of GABAergic input to hypothalamic presympathetic neurons.

  Journal of neurophysiology 20070501

• Characterization of the relaxant response to N,N'-dipropyl-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine in porcine coronary arteries.

  The Journal of pharmacology and experimental therapeutics 20070501

• Molecular docking study of the binding of aminopyridines within the K+ channel.

  Journal of molecular modeling 20070501

• Neurokinins enhance excitability in capsaicin-responsive DRG neurons.

  Experimental neurology 20070501

• Differential dependence of regulatory volume decrease behavior in rabbit corneal epithelial cells on MAPK superfamily activation.

  Experimental eye research 20070501

• Gastric emptying effect by 4-aminopyridine in patients with chronic spinal cord injury.

  Archives of medical research 20070501

• The synthesis, structure and properties of N-acetylated derivatives of ethyl 3-amino-1H-pyrazole-4-carboxylate.

  Chemical & pharmaceutical bulletin 20070501

• Fampridine-SR for multiple sclerosis and spinal cord injury.

  Expert review of neurotherapeutics 20070501

• Neuromuscular paralysis and recovery in mice injected with botulinum neurotoxins A and C.

  The European journal of neuroscience 20070501

• Hippocampal seizures cause depolymerization of filamentous actin in neurons independent of acute morphological changes.

  Brain research 20070427

• [Decreased A-type potassium current mediates the hyperexcitability of nociceptive neurons in the chronically compressed dorsal root ganglia].

  Sheng li xue bao : [Acta physiologica Sinica] 20070425

• Differential intrinsic response dynamics determine synaptic signal processing in frog vestibular neurons.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20070418

• Electrical characterization of interstitial cells of Cajal-like cells and smooth muscle cells isolated from the mouse ureteropelvic junction.

  The Journal of urology 20070401

• The anticonvulsant activity of acetone, the major ketone body in the ketogenic diet, is not dependent on its metabolites acetol, 1,2-propanediol, methylglyoxal, or pyruvic acid.

  Epilepsia 20070401

• Episodic ataxia type 2.

  Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 20070401

• Group I metabotropic glutamate receptor-dependent TRPC channel trafficking in hippocampal neurons.

  Journal of neurochemistry 20070401

• Fampridine-SR in multiple sclerosis: a randomized, double-blind, placebo-controlled, dose-ranging study.

  Multiple sclerosis (Houndmills, Basingstoke, England) 20070401

• [Changes in potassium channel currents of prostate epithelial cell of old rats and significance thereof].

  Zhonghua yi xue za zhi 20070327

• Effects of static magnetic fields on the voltage-gated potassium channel currents in trigeminal root ganglion neurons.

  Neuroscience letters 20070326

• Voltage-gated potassium conductances in Gymnotus electrocytes(AB).

  Neuroscience 20070316

• H2O2 activates redox- and 4-aminopyridine-sensitive Kv channels in coronary vascular smooth muscle.

  American journal of physiology. Heart and circulatory physiology 20070301

• Vasopressin stimulates action potential firing by protein kinase C-dependent inhibition of KCNQ5 in A7r5 rat aortic smooth muscle cells.

  American journal of physiology. Heart and circulatory physiology 20070301

• Endothelium-dependent and -independent relaxation induced by pinocembrin in rat aortic rings.

  Vascular pharmacology 20070301

• Opposing inward and outward conductances regulate rebound discharges in olfactory mitral cells.

  Journal of neurophysiology 20070301

• Sirolimus causes relaxation of human vascular smooth muscle: a novel action of sirolimus mediated via ATP-sensitive potassium channels.

  The Journal of pharmacology and experimental therapeutics 20070301

• Functional contribution of the endothelial component to the vasorelaxing effect of resveratrol and NS 1619, activators of the large-conductance calcium-activated potassium channels.

  Naunyn-Schmiedeberg's archives of pharmacology 20070301

• Involvement of persistent Na+ current in spike initiation in primary sensory neurons of the rat mesencephalic trigeminal nucleus.

  Journal of neurophysiology 20070301

• Pharmacological characterisation of capsaicin-induced relaxations in human and porcine isolated arteries.

  Naunyn-Schmiedeberg's archives of pharmacology 20070301

• Testosterone relaxes isolated human radial artery by potassium channel opening action.

  Journal of pharmacological sciences 20070301

• Simulation of developmental changes in action potentials with ventricular cell models.

  Systems and synthetic biology 20070301

• Different metabolism of glutamatergic and GABAergic compartments in superfused hippocampal slices characterized by nuclear magnetic resonance spectroscopy.

  Neuroscience 20070223

• Roles of volume-sensitive chloride channel in excitotoxic neuronal injury.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20070207

• Phase 2 trial of sustained-release fampridine in chronic spinal cord injury.

  Spinal cord 20070201

• Mechanisms of seizure propagation in a cortical model.

  Journal of computational neuroscience 20070201

• Voltage-gated K+ channels are associated with cell proliferation and cell cycle of ovarian cancer cell.

  Gynecologic oncology 20070201

• Pre-synaptic histamine H3 receptors regulate glutamate, but not GABA release in rat thalamus.

  Neuropharmacology 20070201

• Development of more potent 4-dimethylaminopyridine analogues.

  Organic letters 20070201

• Temperature modulation of ventricular arrhythmogenicity in a canine tissue model of Brugada syndrome.

  Heart rhythm 20070201

• Effects of phorbol-12,13-dibuterate on sodium currents and potassium currents in rat trigeminal ganglion neurons.

  Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20070201

• Influence of procainamide on the neuromuscular blockade caused by rocuronium and investigation on the mechanism of action of procainamide on the neuromuscular junction.

  Revista brasileira de anestesiologia 20070201

• Electrochemical evaluation of 4-(dimethylamino)pyridine adsorption on polycrystalline gold.

  Langmuir : the ACS journal of surfaces and colloids 20070130

• Progress toward a rationally designed, chemically powered rotary molecular motor.

  Journal of the American Chemical Society 20070117

• The dietary flavonoid quercetin activates BKCa currents in coronary arteries via production of H2O2. Role in vasodilatation.

  Cardiovascular research 20070115

• Hemodynamic effects of potent and selective JNK inhibitors in anesthetized rats: implication for targeting protein kinases in metabolic diseases.

  Bioorganic & medicinal chemistry letters 20070115

• Melanocortins and agouti-related protein modulate the excitability of two arcuate nucleus neuron populations by alteration of resting potassium conductances.

  The Journal of physiology 20070115

• Propagation of postsynaptic currents and potentials via gap junctions in GABAergic networks of the rat hippocampus.

  The Journal of physiology 20070115

• Stability studies of ionised and non-ionised 3,4-diaminopyridine: hypothesis of degradation pathways and chemical structure of degradation products.

  Journal of pharmaceutical and biomedical analysis 20070104

• Ion-channel regulation of chondrocyte matrix synthesis in 3D culture under static and dynamic compression.

  Biomechanics and modeling in mechanobiology 20070101

• Ontogeny of chicken ductus arteriosus response to oxygen and vasoconstrictors.

  American journal of physiology. Regulatory, integrative and comparative physiology 20070101

• Presynaptic mechanisms underlying the alpha-lipoic acid facilitation of glutamate exocytosis in rat cerebral cortex nerve terminals.

  Neurochemistry international 20070101

• 4-aminopyridine prevents the conformational changes associated with p/c-type inactivation in shaker channels.

  The Journal of pharmacology and experimental therapeutics 20070101

• Differential contributions of Shaker and Shab K+ currents to neuronal firing patterns in Drosophila.

  Journal of neurophysiology 20070101

• Abnormal intracellular calcium handling underlying T-wave alternans and its hysteresis.

  Cardiology 20070101

• Physiological role of dendrotoxin-sensitive K+ channels in the rat cerebellar Purkinje neurons.

  Physiological research 20070101

• Evidence for a large conductance voltage gated cationic channel in rough endoplasmic reticulum of rat hepatocytes.

  Archives of biochemistry and biophysics 20070101

• Therapeutic considerations for eye movement disorders.

  Developments in ophthalmology 20070101

• Effect of cardioactive drugs on action potential generation and propagation in embryonic stem cell-derived cardiomyocytes.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20070101

• Spontaneous electrical activity in sheep mesenteric lymphatics.

  Lymphatic research and biology 20070101

• Electrophysiological properties of pituitary cells in primary culture from Atlantic cod (Gadus morhua).

  Neuroendocrinology 20070101

• Investigation of relaxant effects of propofol on sheep sphincter of Oddi.

  Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 20070101

• Pharmacological validation of a semi-automated in vitro hippocampal brain slice assay for assessment of seizure liability.

  Journal of pharmacological and toxicological methods 20070101

• Vasorelaxation induced by the new nitric oxide donor cis-[Ru(Cl)(bpy)(2)(NO)](PF(6)) is due to activation of K(Ca) by a cGMP-dependent pathway.

  Vascular pharmacology 20070101

• Inwardly rectifying K(+) (Kir) channels antagonize ictal-like epileptiform activity in area CA1 of the rat hippocampus.

  Hippocampus 20070101

• [The application of 4-aminopyridine in calcium channel inhibitors acute poisoning].

  Przeglad lekarski 20070101

• [Prolonged after-potentials of the myelinated nervous fibres in amphibia after 4-aminopyridine-induced blockage of potassium channels].

  Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20070101

• A novel p38 alpha MAPK inhibitor suppresses brain proinflammatory cytokine up-regulation and attenuates synaptic dysfunction and behavioral deficits in an Alzheimer's disease mouse model.

  Journal of neuroinflammation 20070101

• Immature neurons and GABA networks may contribute to epileptogenesis in pediatric cortical dysplasia.

  Epilepsia 20070101

• Analysis and interpretation of dynamic FDG PET oncological studies using data reduction techniques.

  Biomedical engineering online 20070101

• The role of voltage-gated potassium channels in the regulation of mouse uterine contractility.

  Reproductive biology and endocrinology : RB&E 20070101

• [Treatment of Lambert-Eaton syndrome with 3,4- diaminopyridine and pyridostigmine].

  Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20070101

• Tools for investigating peptide-protein interactions: peptide incorporation of environment-sensitive fluorophores via on-resin derivatization.

  Nature protocols 20070101

• Tools for investigating peptide-protein interactions: peptide incorporation of environment-sensitive fluorophores through SPPS-based 'building block' approach.

  Nature protocols 20070101

• Synthesis of anhydride precursors of the environment-sensitive fluorophores 4-DMAP and 6-DMN.

  Nature protocols 20070101

• The actions of lamotrigine and levetiracetam on the conduction properties of isolated rat sciatic nerve.

  European journal of pharmacology 20061228

• Generation and detection of single metal nanoparticles using scanning electrochemical microscopy techniques.

  The journal of physical chemistry. B 20061221

• Postnatal development of carotid body glomus cell response to hypoxia.

  Respiratory physiology & neurobiology 20061201

• Voltage-gated K+ channels at an early stage of chronic hypoxia-induced pulmonary hypertension in newborn piglets.

  American journal of physiology. Lung cellular and molecular physiology 20061201

• Cyclothiazide prolongs low [Mg2+]-induced seizure-like events.

  Journal of neurophysiology 20061201

• NR2B antagonists restrict spatiotemporal spread of activity in a rat model of cortical dysplasia.

  Epilepsy research 20061201

• Calcium-activated afterhyperpolarizations regulate synchronization and timing of epileptiform bursts in hippocampal CA3 pyramidal neurons.

  Journal of neurophysiology 20061201

• Hydrogen peroxide: a feed-forward dilator that couples myocardial metabolism to coronary blood flow.

  Arteriosclerosis, thrombosis, and vascular biology 20061201

• Consistent dynamics suggests tight regulation of biophysical parameters in a small network of bursting neurons.

  Journal of neurobiology 20061201

• Activation of potassium channels by tempol in arterial smooth muscle cells from normotensive and deoxycorticosterone acetate-salt hypertensive rats.

  Hypertension (Dallas, Tex. : 1979) 20061201

• (+/-)-Naringenin as large conductance Ca(2+)-activated K+ (BKCa) channel opener in vascular smooth muscle cells.

  British journal of pharmacology 20061201

• Inotropic effects of the K+ channel blocker 3,4-diaminopyridine: differential responses of rat soleus and extensor digitorum longus.

  IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society 20061201

• Studies on the mechanisms underlying beta-adrenoceptor-mediated relaxation of rat abdominal aorta.

  Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20061201

• K+ channels involved in contractility of rabbit small intestine.

  Journal of physiology and biochemistry 20061201

• Oxyhemoglobin-induced suppression of voltage-dependent K+ channels in cerebral arteries by enhanced tyrosine kinase activity.

  Circulation research 20061124

• Modification of both the electrophilic center and substituents on the nonleaving group in pyridinolysis of O-4-nitrophenyl benzoate and thionobenzoates.

  The Journal of organic chemistry 20061124

• Theoretical prediction of relative and absolute pKa values of aminopyridines.

  Biophysical chemistry 20061120

• Unexpected inhibitory regulation of glutamate release from rat cerebrocortical nerve terminals by presynaptic 5-hydroxytryptamine-2A receptors.

  Journal of neuroscience research 20061115

• Broad-spectrum effects of 4-aminopyridine to modulate amyloid beta1-42-induced cell signaling and functional responses in human microglia.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20061108

• Synthesis and spectroscopic characterization of copper(II) tetraazaiminooxime macrocyclic complexes--a tetragonal distortion analysis.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20061101

• H2O2-induced redox-sensitive coronary vasodilation is mediated by 4-aminopyridine-sensitive K+ channels.

  American journal of physiology. Heart and circulatory physiology 20061101

• Heterogeneous potassium conductances contribute to the diverse firing properties of postnatal mouse vestibular ganglion neurons.

  Journal of neurophysiology 20061101

• Properties of a time-dependent potassium current in pig atrium: evidence for a role of kv1.5 in repolarization.

  The Journal of pharmacology and experimental therapeutics 20061101

• Pharmacological and molecular evidence for the involvement of Kv4.3 in ultra-fast activating K+ currents in murine portal vein myocytes.

  British journal of pharmacology 20061101

• Potassium channels-mediated vasorelaxation of rat aorta induced by resveratrol.

  Basic & clinical pharmacology & toxicology 20061101

• Imipramine inhibits A-type delayed rectifier and ATP-sensitive K+ currents independent of G-protein and protein kinase C in murine proximal colonic myocytes.

  Archives of pharmacal research 20061101

• [Influence of 4-aminopyridine on cell proliferation through inhibiting voltage-gated K+ channel in ovarian cancer].

  Zhonghua fu chan ke za zhi 20061101

• [Calcium-dependent chloride channels in plasma membrane of oocytes from toad, Bufo bufo gargarizans].

  Sheng li xue bao : [Acta physiologica Sinica] 20061025

• [Electrophysiological study on rat conduit pulmonary artery smooth muscle cells under normoxia and acute hypoxia].

  Sheng li xue bao : [Acta physiologica Sinica] 20061025

• Regulation of synaptic input to hypothalamic presympathetic neurons by GABA(B) receptors.

  Neuroscience 20061013

• Histamine decreases myogenic tone in rat cerebral arteries by H2-receptor-mediated KV channel activation, independent of endothelium and cyclic AMP.

  European journal of pharmacology 20061010

• Two opposing roles of 4-AP-sensitive K+ current in initiation and invasion of spikes in rat mesencephalic trigeminal neurons.

  Journal of neurophysiology 20061001

• Reactivity of human placental chorionic plate vessels from pregnancies complicated by intrauterine growth restriction (IUGR).

  Biology of reproduction 20061001

• Kv7/KCNQ/M-channels in rat glutamatergic hippocampal axons and their role in regulation of excitability and transmitter release.

  The Journal of physiology 20061001

• Mechanisms of vasoactive intestinal peptide-elicited coronary vasodilation in the isolated perfused rat heart.

  Neuropeptides 20061001

• Comparison of endothelial function in the carotid artery between normal and short-term hypercholesterolemic rabbits.

  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20061001

• Role of megakaryoblastic acute leukemia-1 in ERK1/2-dependent stimulation of serum response factor-driven transcription by BDNF or increased synaptic activity.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20060927

• Interleukin-1beta induces hyperpolarization and modulates synaptic inhibition in preoptic and anterior hypothalamic neurons.

  Neuroscience 20060915

• Properties of ion channels in rabbit mesenchymal stem cells from bone marrow.

  Biochemical and biophysical research communications 20060915

• Immature neuronal phenotype derived from mouse skin precursor cells differentiated in vitro.

  Brain research 20060913

• Treatment of the gravity dependence of downbeat nystagmus with 3,4-diaminopyridine.

  Neurology 20060912

• Barium ions inhibit the dynamic response of guinea-pig corneal cold receptors to heating but not to cooling.

  The Journal of physiology 20060901

• 4-aminopyridine, a Kv channel antagonist, prevents apoptosis of rat cerebellar granule neurons.

  Neuropharmacology 20060901

• The H current blocker ZD7288 decreases epileptiform hyperexcitability in the rat neocortex by depressing synaptic transmission.

  Neuropharmacology 20060901

• Mechanisms underlying biochanin A-induced relaxation of the aorta differ between normotensive and hypertensive rats.

  Clinical and experimental pharmacology & physiology 20060901

• Determination of some heavy metal cations in molten snow by transient isotachophoresis/ capillary zone electrophoresis.

  Journal of separation science 20060901

• Serotonin depolarizes the membrane potential in rat mesenteric artery myocytes by decreasing voltage-gated K+ currents.

  Biochemical and biophysical research communications 20060825

• Comparative effects of lidocaine and tramadol on injured peripheral nerves.

  European journal of pharmacology 20060814

• The Edinger-Westphal nucleus of the juvenile rat contains transient- and repetitive-firing neurons.

  Neuroscience 20060811

• Expression of pannexin1 in the CNS of adult mouse: cellular localization and effect of 4-aminopyridine-induced seizures.

  Neuroscience 20060811

• Inflammation increases the excitability of masseter muscle afferents.

  Neuroscience 20060811

• A model of the mammalian optic nerve fibre based on experimental data.

  Vision research 20060801

• Evidence for two-pore domain potassium channels in rat cerebral arteries.

  American journal of physiology. Heart and circulatory physiology 20060801

• A-type K+ current of dopamine and GABA neurons in the ventral tegmental area.

  Journal of neurophysiology 20060801

• Exocytotic release of creatine in rat brain.

  Synapse (New York, N.Y.) 20060801

• Population patch clamp improves data consistency and success rates in the measurement of ionic currents.

  Journal of biomolecular screening 20060801

• Termination of epileptiform activity by cooling in rat hippocampal slice epilepsy models.

  Epilepsy research 20060801

• The role of potassium channels in the vasodilatory effect of levosimendan in human internal thoracic arteries.

  European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20060801

• Hydrogen sulfide mediates hypoxia-induced relaxation of trout urinary bladder smooth muscle.

  The Journal of experimental biology 20060801

• Expression and function of potassium channels in the human placental vasculature.

  American journal of physiology. Regulatory, integrative and comparative physiology 20060801

• [Regulating effects of delayed rectifier potassium channel on the tone of human passively sensitized bronchial smooth muscle].

  Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20060801

• hKv1.5 channels play a pivotal role in the functions of human alveolar macrophages.

  Biochemical and biophysical research communications 20060728

• Membrane potassium currents in human radial artery and their regulation by nitric oxide donor.

  Cardiovascular research 20060715

• Solvent polarity effect on excited-state lifetime of carotenoids and some dyes.

  Biopolymers 20060701

• Potassium channel blockers in multiple sclerosis: neuronal Kv channels and effects of symptomatic treatment.

  Pharmacology & therapeutics 20060701

• Src family tyrosine kinases differentially modulate exocytosis from rat brain nerve terminals.

  Neurochemistry international 20060701

• Neuromuscular stimulation causes muscle phenotype-dependent changes in the expression of the IGFs and their binding proteins in developing slow and fast muscle of chick embryos.

  Developmental dynamics : an official publication of the American Association of Anatomists 20060701

• Hypoosmolar conditions reduce extracellular volume fraction and enhance epileptiform activity in the CA3 region of the immature rat hippocampus.

  Journal of neuroscience research 20060701

• Molecular and Functional Differences between Heart mKv1.7 Channel Isoforms.

  The Journal of general physiology 20060701

• Available treatment options for the management of Lambert-Eaton myasthenic syndrome.

  Expert opinion on pharmacotherapy 20060701

• Neocortical hyperexcitability in a genetic model of absence seizures and its reduction by levetiracetam.

  Epilepsia 20060701

• Synthesis, reactivity, and X-ray crystal structure of some mixed-ligand oxovanadium(V) complexes: first report of binuclear oxovanadium(V) complexes containing 4,4'-bipyridine type bridge.

  Inorganic chemistry 20060626

• Postnatal development of a new type of epileptiform activity in the rat hippocampus.

  Brain research 20060622

• Facilitation of glutamate release by nicotine involves the activation of a Ca2+/calmodulin signaling pathway in rat prefrontal cortex nerve terminals.

  Synapse (New York, N.Y.) 20060615

• Are there protective treatments for cognitive decline in MS?

  Journal of the neurological sciences 20060615

• No benefit of 3,4-diaminopyridine in essential tremor: a placebo-controlled crossover study.

  Neurology 20060613

• Cerebral neurons of transgenic ALS mice are vulnerable to glutamate release stimulation but not to increased extracellular glutamate due to transport blockade.

  Experimental neurology 20060601

• Adenosine stimulates depolarization and rise in cytoplasmic [Ca2+] in type I cells of rat carotid bodies.

  American journal of physiology. Cell physiology 20060601

• Effects of gap junction blockers on human neocortical synchronization.

  Neurobiology of disease 20060601

• Interneuron and pyramidal cell interplay during in vitro seizure-like events.

  Journal of neurophysiology 20060601

• Perivascular adipose tissue and mesenteric vascular function in spontaneously hypertensive rats.

  Arteriosclerosis, thrombosis, and vascular biology 20060601

• Esterification of 7-theophyllineacetic acid with diethylene glycol monomethyl ether.

  Acta pharmaceutica (Zagreb, Croatia) 20060601

• Presynaptic GABA(B) receptors regulate retinohypothalamic tract synaptic transmission by inhibiting voltage-gated Ca2+ channels.

  Journal of neurophysiology 20060601

• beta-adrenoceptor mediated responses in rat pulmonary artery: putative role of TASK-1 related K channels.

  Naunyn-Schmiedeberg's archives of pharmacology 20060601

• The effects of presynaptic calcium channel modulation by roscovitine on transmitter release at the adult frog neuromuscular junction.

  The European journal of neuroscience 20060601

• The functional significance of gap junction channels in the epileptogenicity and seizure susceptibility of juvenile rats.

  Epilepsia 20060601

• Extended-release bupropion for patients with major depressive disorder presenting with symptoms of reduced energy, pleasure, and interest: findings from a randomized, double-blind, placebo-controlled study.

  The Journal of clinical psychiatry 20060601

• Effects of 4-aminopyridine on classical conditioning of the rabbit (Oryctolagus cuniculus) nictitating membrane response.

  Behavioural pharmacology 20060601

• Mechanisms underlying the relaxation induced by isokaempferide from Amburana cearensis in the guinea-pig isolated trachea.

  Life sciences 20060530

• Unique combination of anatomy and physiology in cells of the rat paralaminar thalamic nuclei adjacent to the medial geniculate body.

  The Journal of comparative neurology 20060520

• Dual mechanisms of angiotensin-induced activation of mouse sympathetic neurones.

  The Journal of physiology 20060515

• Surface plasmon resonance spectroscopy study of electrostatically adsorbed layers.

  Langmuir : the ACS journal of surfaces and colloids 20060509

• Intraperitoneal instillation of polihexanide produces hypotension and vasodilation: in vivo and in vitro study in rats.

  International journal of colorectal disease 20060501

• Alterations of behavior and spatial learning after unilateral entorhinal ablation of rats.

  Life sciences 20060501

• Involvement of Kv1.1 and Nav1.5 in proliferation of gastric epithelial cells.

  Journal of cellular physiology 20060501

• MR-visible coatings for endovascular device visualization.

  Journal of magnetic resonance imaging : JMRI 20060501

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• Potassium channel-related relaxation by levosimendan in the human internal mammary artery.

  The Annals of thoracic surgery 20060501

• The mechanism of endothelium-independent relaxation induced by the wine polyphenol resveratrol in human internal mammary artery.

  Journal of pharmacological sciences 20060501

• Altered seizure susceptibility in mice lacking the Ca(v)2.3 E-type Ca2+ channel.

  Epilepsia 20060501

• Potassium channels in the vasodilating action of levosimendan on the human umbilical artery.

  Journal of the Society for Gynecologic Investigation 20060501

• Endothelium-derived factors and k+ channels are involved in the vasorelaxation induced by Sida cordifolia L. in the rat superior mesenteric artery.

  Die Pharmazie 20060501

• Activity-dependent movements of postsynaptic scaffolds at inhibitory synapses.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20060426

• Metformin reduces blood pressure and restores endothelial function in aorta of streptozotocin-induced diabetic rats.

  Life sciences 20060425

• Indapamide induces apoptosis of GH3 pituitary cells independently of its inhibition of voltage-dependent K+ currents.

  European journal of pharmacology 20060424

• Vasomotor action of insulin on the rabbit normal cavernous smooth muscle.

  European journal of pharmacology 20060424

• 18F-fluorodeoxyglucose hypometabolism in cerebellar tonsil and flocculus in downbeat nystagmus.

  Neuroreport 20060424

• Nitric oxide-dependent vasorelaxation induced by extractive solutions and fractions of Maytenus ilicifolia Mart ex Reissek (Celastraceae) leaves.

  Journal of ethnopharmacology 20060406

• Intrinsic optical signal imaging of neocortical seizures: the 'epileptic dip'.

  Neuroreport 20060403

• Kv channels contribute to nitric oxide- and atrial natriuretic peptide-induced relaxation of a rat conduit artery.

  The Journal of pharmacology and experimental therapeutics 20060401

• A role for voltage-gated, but not Ca2+-activated, K+ channels in regulating spontaneous contractile activity in myometrium from virgin and pregnant rats.

  British journal of pharmacology 20060401

• Possible mediators involved in decreasing peripheral vascular resistance with blackcurrant concentrate (BC) in hind-limb perfusion model of the rat.

  Vascular pharmacology 20060401

• Effects in vitro and in vivo of a gap junction blocker on epileptiform activities in a genetic model of absence epilepsy.

  Epilepsy research 20060401

• Cannabinoid agonists induce relaxation in the bovine ophthalmic artery: evidences for CB1 receptors, nitric oxide and potassium channels.

  British journal of pharmacology 20060401

• Fetal exposure to 3,4-diaminopyridine in a pregnant woman with congenital myasthenia syndrome.

  The Annals of pharmacotherapy 20060401

• The role of potassium channels in relaxant effect of levosimendan in rat small mesenteric arteries.

  Cardiovascular drugs and therapy 20060401

• Early effects of embryonic movement: 'a shot out of the dark'.

  Journal of anatomy 20060401

• Single-channel response of hamster oocytes to fertilization with homologous spermatozoa.

  Biocell : official journal of the Sociedades Latinoamericanas de Microscopia Electronica ... et. al 20060401

• [Influence of lidocaine on the neuromuscular block produced by rocuronium: study in rat phrenic-diaphragmatic nerve preparation.].

  Revista brasileira de anestesiologia 20060401

• Laminar analysis of initiation and spread of epileptiform discharges in three in vitro models.

  Brain research bulletin 20060331

• A unique example of a high symmetry three- and four-connected hydrogen bonded 3D-network.

  Chemical communications (Cambridge, England) 20060314

• 1,4-Diazabicyclo[2.2.2]octane derivatives: a novel class of voltage-gated potassium channel blockers.

  Molecular pharmacology 20060301

• Functional changes in genetically dysmyelinated spinal cord axons of shiverer mice: role of juxtaparanodal Kv1 family K+ channels.

  Journal of neurophysiology 20060301

• Endogenous acetylcholine enhances synchronized interneuron activity in rat neocortex.

  Journal of neurophysiology 20060301

• Investigation of the role of TASK-2 channels in rat pulmonary arteries; pharmacological and functional studies following RNA interference procedures.

  British journal of pharmacology 20060301

• Different anticonvulsive effects of hesperidin and its aglycone hesperetin on electrical activity in the rat hippocampus in-vitro.

  The Journal of pharmacy and pharmacology 20060301

• [Fatigue and episodic exhaustion as a feature of multiple sclerosis].

  Revue neurologique 20060301

• [Pathophysiology and treatment of fatigue in multiple sclerosis].

  Revue neurologique 20060301

• Influence of extracellular pH on the modulatory effect of zinc ions on Kv1.3 potassium channels.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20060301

• Possible activation of the NO-cyclic GMP-protein kinase G-K+ channels pathway by gabapentin on the formalin test.

  Pharmacology, biochemistry, and behavior 20060301

• Transient-outward K+ channel inhibition facilitates L-type Ca2+ current in heart.

  Journal of cardiovascular electrophysiology 20060301

• A metallocene-pyrrolidinopyridine nucleophilic catalyst for asymmetric synthesis.

  Organic letters 20060216

• Serotonergic enhancement of a 4-AP-sensitive current mediates the synaptic depression phase of spike timing-dependent neuromodulation.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20060215

• A xanthine-based epithelium-dependent airway relaxant KMUP-3 (7-[2-[4-(4-nitrobenzene)piperazinyl]ethyl]-1,3-dimethylxanthine) increases respiratory performance and protects against tumor necrosis factor-alpha-induced tracheal contraction, involving nitric oxide release and expression of cGMP and protein kinase G.

  The Journal of pharmacology and experimental therapeutics 20060201

• Dose responses of three 4-aminopyridine derivatives on axonal conduction in spinal cord trauma.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20060201

• Presynaptic effects of anandamide and WIN55,212-2 on glutamatergic nerve endings isolated from rat hippocampus.

  Neurochemistry international 20060201

• Facilitatory effect of aspirin on glutamate release from rat hippocampal nerve terminals: involvement of protein kinase C pathway.

  Neurochemistry international 20060201

• An unusual case of 4-aminopyridine toxicity.

  The Journal of emergency medicine 20060201

• Enantioselective TADMAP-catalyzed carboxyl migration reactions for the synthesis of stereogenic quaternary carbon.

  Journal of the American Chemical Society 20060125

• Effect of genistein on voltage-gated potassium channels in guinea pig proximal colon smooth muscle cells.

  World journal of gastroenterology 20060121

• Concerted action between Ca2+ and hyperosmolality initiates sperm motility in amphioxus Branchiostoma belcheri tsingtauense.

  Theriogenology 20060120

• Capsaicin-induced, capsazepine-insensitive relaxation of the guinea-pig ileum.

  European journal of pharmacology 20060113

• Contribution of glibenclamide-sensitive, ATP-dependent K+ channel activation to acetophenone analogues-mediated in vitro pulmonary artery relaxation of rat.

  Life sciences 20060102

• Voltage-dependent K+ channel acts as sex steroid sensor in endocrine cells of the human ovary.

  Journal of cellular physiology 20060101

• Structural and functional MRI following 4-aminopyridine-induced seizures: a comparative imaging and anatomical study.

  Neurobiology of disease 20060101

• Voltage-dependent currents in isolated vestibular afferent calyx terminals.

  Journal of neurophysiology 20060101

• Volatile anesthetic effects on glutamate versus GABA release from isolated rat cortical nerve terminals: 4-aminopyridine-evoked release.

  The Journal of pharmacology and experimental therapeutics 20060101

• Pharmacological characterization of ionic currents that regulate high-frequency spontaneous activity of electromotor neurons in the weakly electric fish, Apteronotus leptorhynchus.

  Journal of neurobiology 20060101

• Potentiation by high potassium of lipopolysaccharide-induced nitric oxide production from cultured astrocytes.

  Neurochemistry international 20060101

• Stereoselective effects of the novel anticonvulsant lacosamide against 4-AP induced epileptiform activity in rat visual cortex in vitro.

  Neuropharmacology 20060101

• An investigation into the effect of the type IV phosphodiesterase inhibitor rolipram in the modulation of glutamate release from rat prefrontocortical nerve terminals.

  Synapse (New York, N.Y.) 20060101

• A delayed ATP-elicited K+ current in freshly isolated smooth muscle cells from mouse aorta.

  British journal of pharmacology 20060101

• Fictive locomotor patterns generated by tetraethylammonium application to the neonatal rat spinal cord in vitro.

  Neuroscience 20060101

• The effect of BAPTA and 4AP in scala media on transduction and cochlear gain.

  Hearing research 20060101

• Cold sensitivity in axotomized fibers of experimental neuromas in mice.

  Pain 20060101

• Cocaine elicits action potential bursts in a central snail neuron: the role of delayed rectifying K+ current.

  Neuroscience 20060101

• Enhanced excitability of rat trigeminal root ganglion neurons via decrease in A-type potassium currents following temporomandibular joint inflammation.

  Neuroscience 20060101

• Carbenoxolone does not cross the blood brain barrier: an HPLC study.

  BMC neuroscience 20060101

• Epileptiform activity induced by pharmacologic reduction of M-current in the developing hippocampus in vitro.

  Epilepsia 20060101

• Pharmacological evidence for calcium channel inhibition by danshen (Salvia miltiorrhiza) on rat isolated femoral artery.

  Journal of cardiovascular pharmacology 20060101

• Systemic blood pressure response to the inhibition of two hyperpolarizing pathways: a comparison to NO-synthase inhibition.

  Physiological research 20060101

• Inhibition by endomorphin-1 and endomorphin-2 of excitatory transmission in adult rat substantia gelatinosa neurons.

  Neuroscience 20060101

• Multicellular tumour spheroid as a model for evaluation of [18F]FDG as biomarker for breast cancer treatment monitoring.

  Cancer cell international 20060101

• [Effect of xymedone on high-voltage-activated Ca2+ currents in pyramidal neurons of the entorhinal cortex].

  Eksperimental'naia i klinicheskaia farmakologiia 20060101

• Ventricular slices of adult mouse hearts--a new multicellular in vitro model for electrophysiological studies.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20060101

• Alterations of seizure-induced c-fos immunolabelling and gene expression in the rat cerebral cortex following dexamethasone treatment.

  Acta histochemica 20060101

• Nerve injury induces robust allodynia and ectopic discharges in Nav1.3 null mutant mice.

  Molecular pain 20060101

• Oscillatory circuits underlying locomotor networks in the rat spinal cord.

  Critical reviews in neurobiology 20060101

• Potassium currents in isolated statocyst neurons and RPeD1 in the pond snail, Lymnaea stagnalis.

  Journal of neurophysiology 20051201

• Effect of 4-aminopyridine (4-AP) on the spontaneous activity and neuromuscular junction in the rat colon.

  Pharmacological research 20051201

• Ca2+-activated K+-current density is correlated with soma size in rat vestibular-afferent neurons in culture.

  Journal of neurophysiology 20051201

• Effects of I(Ks) channel inhibitors in insulin-secreting INS-1 cells.

  Pflugers Archiv : European journal of physiology 20051201

• Astrocytic glutamate release-induced transient depolarization and epileptiform discharges in hippocampal CA1 pyramidal neurons.

  Journal of neurophysiology 20051201

• Oxaliplatin induces hyperexcitability at motor and autonomic neuromuscular junctions through effects on voltage-gated sodium channels.

  British journal of pharmacology 20051201

• In vivo imaging of dendritic spines during electrographic seizures.

  Annals of neurology 20051201

• Transient voltage-dependent potassium currents are reduced in NTS neurons isolated from renal wrap hypertensive rats.

  Journal of neurophysiology 20051201

• Effects of retigabine on the neurodegeneration and extracellular glutamate changes induced by 4-aminopyridine in rat hippocampus in vivo.

  Neurochemical research 20051201

• Late N-methyl-D-aspartate receptor blockade rescues hippocampal neurons from excitotoxic stress and death after 4-aminopyridine-induced epilepsy.

  The European journal of neuroscience 20051201

• Probable activation of the opioid receptor-nitric oxide-cyclic GMP-K+ channels pathway by codeine.

  Pharmacology, biochemistry, and behavior 20051201

• Characterization of potassium channels involved in volume regulation of human spermatozoa.

  Molecular human reproduction 20051201

• Potassium currents in primary cultured astrocytes from the rat corpus callosum.

  Journal of neurocytology 20051201

• PP2 inhibits glutamate release from nerve endings by affecting vesicle mobilization.

  Neuroreport 20051128

• Glutamatergic regulation of the p70S6 kinase in primary mouse neurons.

  The Journal of biological chemistry 20051118

• Enhanced oxidative stress impairs cAMP-mediated dilation by reducing Kv channel function in small coronary arteries of diabetic rats.

  American journal of physiology. Heart and circulatory physiology 20051101

• Attenuation of apoptosis in enterocytes by blockade of potassium channels.

  American journal of physiology. Gastrointestinal and liver physiology 20051101

• Electronic, infrared, and Raman spectral studies of the reaction of iodine with 4-aminopyridine.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20051101

• Cholinergic modulation of status epilepticus in the rat barrel field region of primary somatosensory cortex.

  Experimental neurology 20051101

• Transient outward K+ currents in rat dissociated subfornical organ neurones and angiotensin II effects.

  The Journal of physiology 20051101

• Functional characterization and expression of endothelin receptors in rat carotid artery: involvement of nitric oxide, a vasodilator prostanoid and the opening of K+ channels in ETB-induced relaxation.

  British journal of pharmacology 20051101

• KMUP-1 activates BKCa channels in basilar artery myocytes via cyclic nucleotide-dependent protein kinases.

  British journal of pharmacology 20051101

• Depolarization-induced release of ethanolamine from brain synaptic preparations in vitro.

  Brain research 20051026

• From uncharged to decacationic molecules: syntheses and spectroscopic properties of heteroarenium-substituted pyridines.

  Organic & biomolecular chemistry 20051021

• Design and synthesis of a new type of ferrocene-based planar chiral DMAP analogues. A new catalyst system for asymmetric nucleophilic catalysis.

  The Journal of organic chemistry 20051014

• Sex differences in the cannabinoid modulation of an A-type K+ current in neurons of the mammalian hypothalamus.

  Journal of neurophysiology 20051001

• Dopamine modulation of two delayed rectifier potassium currents in a small neural network.

  Journal of neurophysiology 20051001

• Mechanism of the endothelium-dependent vasodilator effect of an alcohol-free extract obtained from a vinifera grape skin.

  Pharmacological research 20051001

• Synthesis of phosphatidylcholine: an improved method without using the cadmium chloride complex of sn-glycero-3-phosphocholine.

  Chemistry and physics of lipids 20051001

• Electrophysiological and functional effects of the KCNQ channel blocker XE991 on murine portal vein smooth muscle cells.

  British journal of pharmacology 20051001

• Lateral entorhinal cortex lesions rearrange afferents, glutamate receptors, increase seizure latency and suppress seizure-induced c-fos expression in the hippocampus of adult rat.

  Journal of neurochemistry 20051001

• Quinine, a blocker of neuronal cx36 channels, suppresses seizure activity in rat neocortex in vivo.

  Epilepsia 20051001

• Independent roles of calcium and voltage-dependent potassium currents in controlling spike frequency adaptation in lateral amygdala pyramidal neurons.

  The European journal of neuroscience 20051001

• Perivascular adipose tissue modulates vascular function in the human internal thoracic artery.

  The Journal of thoracic and cardiovascular surgery 20051001

• Isolation of 4-aminopyridine resistant mutants affecting alkali-insoluble glucan content of cell walls in Saccharomyces cerevisiae.

  Indian journal of experimental biology 20051001

• Long-range oscillatory Ca2+ waves in rat spinal dorsal horn.

  The European journal of neuroscience 20051001

• 8-isoprostaglandin E(2) activates Ca(2+)-dependent K(+) current via cyclic AMP signaling pathway in murine renal artery.

  European journal of pharmacology 20050927

• Novel inhibitor of p38 MAP kinase as an anti-TNF-alpha drug: discovery of N-[4-[2-ethyl-4-(3-methylphenyl)-1,3-thiazol-5-yl]-2-pyridyl]benzamide (TAK-715) as a potent and orally active anti-rheumatoid arthritis agent.

  Journal of medicinal chemistry 20050922

• Heterogeneous expression and regulation of hippocampal prostaglandin E2 receptors.

  Journal of neuroscience research 20050915

• Inhibition of Na+ channel currents in rat myoblasts by 4-aminopyridine.

  Toxicology and applied pharmacology 20050915

• Inducibility of abnormal automaticity and triggered activity in myocardial sleeves of canine pulmonary veins.

  International journal of cardiology 20050915

• GABAergic excitation promotes neuronal differentiation in adult hippocampal progenitor cells.

  Neuron 20050915

• Transient potassium conductances protect nucleus tractus solitarius neurons from NMDA induced excitotoxic plateau depolarizations.

  Brain research 20050914

• Reduced molecular expression of K(+) channel proteins in vascular smooth muscle from rats made hypertensive with N{omega}-nitro-L-arginine.

  American journal of physiology. Heart and circulatory physiology 20050901

• Reduced functional expression of K(+) channels in vascular smooth muscle cells from rats made hypertensive with N{omega}-nitro-L-arginine.

  American journal of physiology. Heart and circulatory physiology 20050901

• Inhibition of the A-type K+ channels of dorsal root ganglion neurons by the long-duration anesthetic butamben.

  The Journal of pharmacology and experimental therapeutics 20050901

• Multiple potassium channels mediate nitric oxide-induced inhibition of rat vascular smooth muscle cell proliferation.

  Nitric oxide : biology and chemistry 20050901

• Development of novel 4-aminopyridine derivatives as potential treatments for neurological injury and disease.

  European journal of medicinal chemistry 20050901

• Antihypertensive and endothelium-dependent vasodilator effects of Alpinia zerumbet, a medicinal plant.

  Journal of cardiovascular pharmacology 20050901

• A-type potassium current in retinal arteriolar smooth muscle cells.

  Investigative ophthalmology & visual science 20050901

• Transient K+ current is blocked by lanthanum in Drosophila neurons.

  Neurochemical research 20050901

• Paired motor neuron-muscle recordings in zebrafish test the receptor blockade model for shaping synaptic current.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20050831

• Kv1.5 surface expression is modulated by retrograde trafficking of newly endocytosed channels by the dynein motor.

  Circulation research 20050819

• How to enhance ipsilateral actions of pyramidal tract neurons.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20050810

• Cholinergic suppression of KCNQ channel currents enhances excitability of striatal medium spiny neurons.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20050810

• Insulin-activated, K+-channel-sensitive Akt pathway is primary mediator of ML-1 cell proliferation.

  American journal of physiology. Cell physiology 20050801

• A functional glutamatergic neurone network in the medial septum and diagonal band area.

  The Journal of physiology 20050801

• Rat subicular networks gate hippocampal output activity in an in vitro model of limbic seizures.

  The Journal of physiology 20050801

• Nuclear factor-kappaB activation by reactive oxygen species mediates voltage-gated K+ current enhancement by neurotoxic beta-amyloid peptides in nerve growth factor-differentiated PC-12 cells and hippocampal neurones.

  Journal of neurochemistry 20050801

• Pharmacological evidence for the activation of Ca2+-activated K+ channels by meloxicam in the formalin test.

  Pharmacology, biochemistry, and behavior 20050801

• Voltage-gated potassium channels regulate the response of retinal growth cones to axon extension and guidance cues.

  The European journal of neuroscience 20050801

• Demonstration of kynurenine aminotransferases I and II and characterization of kynurenic acid synthesis in oligodendrocyte cell line (OLN-93).

  Neurochemical research 20050801

• Cellular mechanisms underlying cutaneous pressure-induced vasodilation: in vivo involvement of potassium channels.

  American journal of physiology. Heart and circulatory physiology 20050701

• Optically recorded response of the superficial dorsal horn: dissociation from neuronal activity, sensitivity to formalin-evoked skin nociceptor activation.

  Journal of neurophysiology 20050701

• Parathyroid hormone-related protein-mediated responses in pulmonary arteries and veins of newborn lambs.

  American journal of physiology. Lung cellular and molecular physiology 20050701

• Quantitative analysis of voltage-gated potassium currents from primary equine (Equus caballus) and elephant (Loxodonta africana) articular chondrocytes.

  American journal of physiology. Regulatory, integrative and comparative physiology 20050701

• Effects of alpha-dendrotoxin on K+ currents and action potentials in tetrodotoxin-resistant adult rat trigeminal ganglion neurons.

  The Journal of pharmacology and experimental therapeutics 20050701

• Novel method to assess cardiac electrophysiology in the rat: characterization of standard ion channel blockers.

  Journal of cardiovascular pharmacology 20050701

• Design of novel injectable cationic microspheres based on aminated gelatin for prolonged insulin action.

  The Journal of pharmacy and pharmacology 20050701

• Arsenic trioxide-induced hela cell death is partially prevented by K+ channel blockers.

  Yao xue xue bao = Acta pharmaceutica Sinica 20050701

• NCAM 180 acting via a conserved C-terminal domain and MLCK is essential for effective transmission with repetitive stimulation.

  Neuron 20050616

• Horizontal spread of activity in neocortical inhibitory networks.

  Brain research. Developmental brain research 20050609

• Preparation of biodegradable networks by photo-crosslinking lactide, epsilon-caprolactone and trimethylene carbonate-based oligomers functionalized with fumaric acid monoethyl ester.

  Biomaterials 20050601

• A-type voltage-gated K+ currents influence firing properties of isolectin B4-positive but not isolectin B4-negative primary sensory neurons.

  Journal of neurophysiology 20050601

• The effects of Delta9-tetrahydrocannabinol in rat mesenteric vasculature, and its interactions with the endocannabinoid anandamide.

  British journal of pharmacology 20050601

• Vinpocetine blockade of sodium channels inhibits the rise in sodium and calcium induced by 4-aminopyridine in synaptosomes.

  Neurochemistry international 20050601

• Output-mode transitions are controlled by prolonged inactivation of sodium channels in pyramidal neurons of subiculum.

  PLoS biology 20050601

• Structural and functional alterations of spinal cord axons in adult Long Evans Shaker (LES) dysmyelinated rats.

  Experimental neurology 20050601

• Demonstration of kynurenine aminotransferases I and II and characterization of kynurenic acid synthesis in cultured cerebral cortical neurons.

  Journal of neuroscience research 20050601

• Testosterone relaxes human internal mammary artery in vitro.

  Journal of cardiovascular pharmacology 20050601

• Dysfunction of the brain calcium channel CaV2.1 in absence epilepsy and episodic ataxia--a comment.

  Brain : a journal of neurology 20050601

• Intracellular calcium disturbances induced by arsenic and its methylated derivatives in relation to genomic damage and apoptosis induction.

  Environmental health perspectives 20050601

• A new chain-like cadmium(II) coordination polymer containing chains of water molecules.

  Acta crystallographica. Section C, Crystal structure communications 20050601

• Anticonvulsant activity of androsterone and etiocholanolone.

  Epilepsia 20050601

• Mechanisms contributing to the exacerbated epileptiform activity in hippocampal slices expressing a C-terminal truncated GABA(B2) receptor subunit.

  Epilepsy research 20050601

• Luteolin induces vasorelaxion in rat thoracic aorta via calcium and potassium channels.

  Die Pharmazie 20050601

• Optical monitoring of progressive synchronization in dentate granule cells during population burst activities.

  The European journal of neuroscience 20050601

• Thyroliberin blocks the potassium A-current in neurons in the respiratory center of adult rats in vitro.

  Neuroscience and behavioral physiology 20050601

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20050601

• A pH-sensitive potassium conductance (TASK) and its function in the murine gastrointestinal tract.

  The Journal of physiology 20050515

• Ginkgolide B, a constituent of Ginkgo biloba, facilitates glutamate exocytosis from rat hippocampal nerve terminals.

  European journal of pharmacology 20050509

• Synaptic depolarizing GABA Response in adults is excitatory and proconvulsive when GABAB receptors are blocked.

  Journal of neurophysiology 20050501

• Frequency-dependent potentiation of voltage-activated responses only in the intact neurohypophysis of the rat.

  Pflugers Archiv : European journal of physiology 20050501

• The effects of putative K+ channel blockers on volume regulation of murine spermatozoa.

  Biology of reproduction 20050501

• In vivo treatment with the K+ channel blocker 4-aminopyridine protects against kainate-induced neuronal cell death through activation of NMDA receptors in murine hippocampus.

  Neuropharmacology 20050501

• Inhibition of persistent sodium current fraction and voltage-gated L-type calcium current by propofol in cortical neurons: implications for its antiepileptic activity.

  Epilepsia 20050501

• Atria selective prolongation by NIP-142, an antiarrhythmic agent, of refractory period and action potential duration in guinea pig myocardium.

  Journal of pharmacological sciences 20050501

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20050501

• Isolation of a new two-dimensional honeycomb carbonato-bridged copper(II) complex exhibiting long-range ferromagnetic ordering.

  Chemical communications (Cambridge, England) 20050428

• Potassium channel blockers inhibit the triggers of attacks in the calcium channel mouse mutant tottering.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20050420

• Treatment for Lambert-Eaton myasthenic syndrome.

  The Cochrane database of systematic reviews 20050418

• Surface complexation modeling of the sorption of 2-, 3-, and 4-aminopyridine by montmorillonite.

  Journal of colloid and interface science 20050415

• Cosorption of Zn(II) and 2-, 3-, or 4-aminopyridine by montmorillonite.

  Journal of colloid and interface science 20050415

• Synthesis and characterization of hydrogen-bonded assemblies of W6S8L6 clusters.

  Inorganic chemistry 20050404

• Effects of the gap junction blocker glycyrrhetinic acid on gastrointestinal smooth muscle cells.

  American journal of physiology. Gastrointestinal and liver physiology 20050401

• New type of synaptically mediated epileptiform activity independent of known glutamate and GABA receptors.

  Journal of neurophysiology 20050401

• BL-1249 [(5,6,7,8-tetrahydro-naphthalen-1-yl)-[2-(1H-tetrazol-5-yl)-phenyl]-amine]: a putative potassium channel opener with bladder-relaxant properties.

  The Journal of pharmacology and experimental therapeutics 20050401

• Effects of haloperidol and clozapine on glutamate release from nerve terminals isolated from rat prefrontal cortex.

  Synapse (New York, N.Y.) 20050401

• Postnatal maturational shift from PKCzeta and voltage-gated K+ channels to RhoA/Rho kinase in pulmonary vasoconstriction.

  Cardiovascular research 20050401

• Nuclear Ca2+ and CaM kinase IV specify hormonal- and Notch-responsiveness.

  Journal of neurochemistry 20050401

• The vasorelaxing effect of CGRP and natriuretic peptides in isolated bovine retinal arteries.

  Investigative ophthalmology & visual science 20050401

• Serum- and glucocorticoid-inducible kinase 1 (SGK1) mediates glucocorticoid-induced inhibition of insulin secretion.

  Diabetes 20050401

• Electrocorticographic and deep intracerebral EEG recording in mice using a telemetry system.

  Brain research. Brain research protocols 20050401

• Effect of 3,4-diaminopyridine on the postural control in patients with downbeat nystagmus.

  Annals of the New York Academy of Sciences 20050401

• Effect of 4-aminopyridine on upbeat and downbeat nystagmus elucidates the mechanism of downbeat nystagmus.

  Annals of the New York Academy of Sciences 20050401

• Terpinen-4-ol: mechanisms of relaxation on rabbit duodenum.

  The Journal of pharmacy and pharmacology 20050401

• Effects of streptozotocin-induced diabetes on Kv channels in rat small coronary smooth muscle cells.

  The Chinese journal of physiology 20050331

• Cu(II) acetate- and Mn(III) acetate-mediated radical reactions of [60]fullerene with ketonic compounds.

  Organic & biomolecular chemistry 20050307

• Properties of synaptically evoked astrocyte calcium signal reveal synaptic information processing by astrocytes.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20050302

• Shal and shaker differential contribution to the K+ currents in the Drosophila mushroom body neurons.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20050302

• Dopamine modulates excitability of basolateral amygdala neurons in vitro.

  Journal of neurophysiology 20050301

• Potential antidepressant LY 367265 presynaptically inhibits the release of glutamate in rat cerebral cortex.

  Synapse (New York, N.Y.) 20050301

• Effects of statins on vascular function of endothelin-1.

  British journal of pharmacology 20050301

• Effects of NS1608, a BK(Ca) channel agonist, on the contractility of guinea-pig urinary bladder in vitro.

  British journal of pharmacology 20050301

• Cognitive deficits in aged rats correlate with levels of L-arginine, not with nNOS expression or 3,4-DAP-evoked transmitter release in the frontoparietal cortex.

  European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20050301

• Neocortical c-fos mRNA transcription in repeated, brief, acute seizures: is c-fos a coincidence detector?

  International journal of molecular medicine 20050301

• 4-aminopyridine restores visual ocular motor function in upbeat nystagmus.

  Journal of neurology, neurosurgery, and psychiatry 20050301

• Complex expression and localization of inactivating Kv channels in cultured hippocampal astrocytes.

  Journal of neurophysiology 20050301

• Impaired KATP channel function in the fetoplacental circulation of patients with type 1 diabetes mellitus.

  American journal of obstetrics and gynecology 20050301

• Characterization of ionic currents in human mesenchymal stem cells from bone marrow.

  Stem cells (Dayton, Ohio) 20050301

• catena-Poly[bis[(eta2-1-allyl-3-aminopyridinium)copper(I)]-di-mu-chloro-copper(I)-di-mu-chloro-copper(I)-di-mu-chloro].

  Acta crystallographica. Section C, Crystal structure communications 20050301

• The modulation of Ca2+ and K+ channels but not changes in cAMP signaling contribute to the inhibition of glutamate release by cannabinoid receptors in cerebrocortical nerve terminals.

  Neuropharmacology 20050301

• Mechanisms of ATP action on motor nerve terminals at the frog neuromuscular junction.

  The European journal of neuroscience 20050301

• [Voltage-activated potassium channel blockers inhibit anisodamine-induced relaxation of rabbit aortic smooth muscles precontracted with noradrenaline].

  Sheng li xue bao : [Acta physiologica Sinica] 20050225

• Contrasting effects of tetraethylammonium and 4-aminopyridine on the gastrointestinal function of mice.

  European journal of pharmacology 20050221

• Examining the out-of-center distortion in the [NbOF5]2- anion.

  Inorganic chemistry 20050221

• Template-assisted cross olefin metathesis.

  Angewandte Chemie (International ed. in English) 20050218

• Activity-dependent long-term potentiation of intrinsic excitability in hippocampal CA1 pyramidal neurons.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20050216

• Protein kinase C activation-induced increases of neural activity are enhanced in the hypothalamus of spontaneously hypertensive rats.

  Brain research 20050208

• Heteromultimeric Kv1 channels contribute to myogenic control of arterial diameter.

  Circulation research 20050204

• Hypercholesterolemia abolishes voltage-dependent K+ channel contribution to adenosine-mediated relaxation in porcine coronary arterioles.

  American journal of physiology. Heart and circulatory physiology 20050201

• Localization and function of the Kv3.1b subunit in the rat medulla oblongata: focus on the nucleus tractus solitarii.

  The Journal of physiology 20050201

• Modulation of the voltage-dependent K+ current by intracellular Mg2+ in rat aortic smooth muscle cells.

  Cardiovascular research 20050201

• Mechanisms underlying the endothelium-independent relaxation induced by angiotensin II in rat aorta.

  Journal of cardiovascular pharmacology 20050201

• Pharmacology of vertigo/nystagmus/oscillopsia.

  Current opinion in neurology 20050201

• Effects of adenosine agonist R-phenylisopropyl-adenosine on halothane anesthesia and antinociception in rats.

  Acta pharmacologica Sinica 20050201

• Single-channel properties support a potential contribution of hyperpolarization-activated cyclic nucleotide-gated channels and If to cardiac arrhythmias.

  Circulation 20050201

• Rapid stimulation causes electrical remodeling in cultured atrial myocytes.

  Journal of molecular and cellular cardiology 20050201

• A TASK-like pH- and amine-sensitive 'leak' K+ conductance regulates neonatal rat facial motoneuron excitability in vitro.

  The European journal of neuroscience 20050201

• Endothelium-dependent and -independent vasorelaxation by a theophylline derivative MCPT: roles of cyclic nucleotides, potassium channel opening and phosphodiesterase inhibition.

  Life sciences 20050107

• Synaptic transmission and synchronous activity is disrupted in hippocampal slices taken from aged TAS10 mice.

  Hippocampus 20050101

• Effect of normoxia and hypoxia on K(+) current and resting membrane potential of fetal rabbit pulmonary artery smooth muscle.

  Physiological research 20050101

• Characterization of outward currents in interstitial cells from the guinea pig bladder.

  The Journal of urology 20050101

• Orexins cause depolarization via nonselective cationic and K+ channels in isolated locus coeruleus neurons.

  Neuroscience research 20050101

• Picosecond kinetics of excited-state charge separation in 4-(dimethylamino)pyridine.

  Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20050101

• Involvement of potassium channels and nitric oxide in tramadol antinociception.

  Pharmacology, biochemistry, and behavior 20050101

• Modulation of available vesicles and release kinetics at the inhibitor of the crayfish neuromuscular junction.

  Neuroscience 20050101

• Participation of ATP-sensitive K+ channels in the peripheral antinociceptive effect of fentanyl in rats.

  Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20050101

• 5-Hydroxytryptamine action in the rat olfactory bulb: in vitro electrophysiological patch-clamp recordings of juxtaglomerular and mitral cells.

  Neuroscience 20050101

• Ectopic action potential generation in cortical interneurons during synchronized GABA responses.

  Neuroscience 20050101

• Biophysical characterization of whole-cell currents in O2-sensitive neurons from the rat glossopharyngeal nerve.

  Neuroscience 20050101

• The application of optical recording of intrinsic signals to simultaneously acquire functional, pathological and localizing information and its potential role in neurosurgery.

  Stereotactic and functional neurosurgery 20050101

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20050101

• Seizure spread through the life cycle: optical imaging in combined brain slices from immature, adult, and senile rats in vitro.

  Neurobiology of disease 20050101

• Repetitive low-frequency stimulation reduces epileptiform synchronization in limbic neuronal networks.

  Neurobiology of disease 20050101

• Decreased vasodilation induced by a new nitric oxide donor in two kidney, one clip hypertensive rats is due to impaired k channel activation.

  Clinical and experimental pharmacology & physiology 20050101

• Characteristics of the electrical oscillations evoked by 4-aminopyridine on dorsal root fibers and their relation to fictive locomotor patterns in the rat spinal cord in vitro.

  Neuroscience 20050101

• Mu-opioid-mediated inhibition of glutamate synaptic transmission in rat central amygdala neurons.

  Neuroscience 20050101

• Heterogeneous expression of voltage-dependent Na+ and K+ channels in mammalian retinal bipolar cells.

  Visual neuroscience 20050101

• [Transformation of electrical activity in the myelinated nerve fibres of amphibia by 4-aminopyridine].

  Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20050101

• Postnatal development of intrinsic GABAergic rhythms in mouse hippocampus.

  Neuroscience 20050101

• Electrophysiological effects of 4-aminopyridine on fictive locomotor activity of the rat spinal cord in vitro.

  Acta neurochirurgica. Supplement 20050101

• Direct evidence for mutual interactions between perineuronal astrocytes and interneurons in the CA1 region of the rat hippocampus.

  Neuroscience 20050101

• Pituitary adenylate cyclase activating polypeptide reduces A-type K+ currents and caspase activity in cultured adult mouse olfactory neurons.

  Neuroscience 20050101

• Activation of neuropeptide Y Y1 receptors inhibits glutamate release through reduction of voltage-dependent Ca2+ entry in the rat cerebral cortex nerve terminals: suppression of this inhibitory effect by the protein kinase C-dependent facilitatory pathway.

  Neuroscience 20050101

• In ovo neuromuscular stimulation alters the skeletal muscle phenotype of the chick.

  Journal of muscle research and cell motility 20050101

• Electrophysiological properties of pluripotent human and mouse embryonic stem cells.

  Stem cells (Dayton, Ohio) 20050101

• Phobic memory and somatic vulnerabilities in anorexia nervosa: a necessary unity?

  Annals of general psychiatry 20050101

• 17beta-estradiol inhibits outward potassium currents recorded in rat parabrachial nucleus cells in vitro.

  Neuroscience 20050101

• Nonselective cation current in rabbit ventricular myocytes.

  Methods and findings in experimental and clinical pharmacology 20050101

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20050101

• Study of the effect of ion channel modulators on photosynthetic oxygen evolution.

  Journal of chemical information and modeling 20050101

• Reduced flavin: NMR investigation of N5-H exchange mechanism, estimation of ionisation constants and assessment of properties as biological catalyst.

  BMC biochemistry 20050101

• Octopamine increases the excitability of neurons in the snail feeding system by modulation of inward sodium current but not outward potassium currents.

  BMC neuroscience 20050101

• Symptomatic and disease-modifying therapies for multiple sclerosis: recent developments: highlights of the 9th Annual Meeting of the Americas Committee for Treatment and Research in Multiple Sclerosis, October 3, 2004, Toronto, Ontario, Canada.

  Reviews in neurological diseases 20050101

• Alterations in conduction characteristics of crushed peripheral nerves.

  Restorative neurology and neuroscience 20050101

• Effect of 15-HETE on potassium channels of rabbit pulmonary arterial smooth muscles during hypoxia.

  Sheng li xue bao : [Acta physiologica Sinica] 20041225

• Heterogeneity of action potential durations in isolated mouse left and right atria recorded using voltage-sensitive dye mapping.

  American journal of physiology. Heart and circulatory physiology 20041201

• Inhibition of tumor cell proliferation by sigma ligands is associated with K+ Channel inhibition and p27kip1 accumulation.

  The Journal of pharmacology and experimental therapeutics 20041201

• Effect of 4-aminopyridine on gait in ambulatory spinal cord injuries: a double-blind, placebo-controlled, crossover trial.

  Spinal cord 20041201

• Diltiazem inhibits hKv1.5 and Kv4.3 currents at therapeutic concentrations.

  Cardiovascular research 20041201

• Relaxation induced by acetylcholine involves endothelium-derived hyperpolarizing factor in 2-kidney 1-clip hypertensive rat carotid arteries.

  Pharmacology 20041201

• Vinpocetine prevents 4-aminopyridine-induced changes in the EEG, the auditory brainstem responses and hearing.

  Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 20041201

• Stressor-related impairment of synaptic transmission in hippocampal slices from alpha-synuclein knockout mice.

  The European journal of neuroscience 20041201

• Low-voltage-activated A-current controls the firing dynamics of mouse hypothalamic orexin neurons.

  The European journal of neuroscience 20041201

• Kv3 voltage-gated potassium channels regulate neurotransmitter release from mouse motor nerve terminals.

  The European journal of neuroscience 20041201

• The relaxant effect of vasoactive intestinal polypeptide in the isolated canine uterine artery: the role of endothelium.

  Journal of veterinary medicine. A, Physiology, pathology, clinical medicine 20041201

• Electrophysiological and pharmacological characterization of K+-currents in muscle fibres isolated from the ventral sucker of Fasciola hepatica.

  Parasitology 20041201

• [Effect of potassium channel on the proliferation, apoptosis and related-gene expression in human bronchial smooth muscle cells].

  Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20041201

• Repeated 4-aminopyridine seizures reduce parvalbumin content in the medial mammillary nucleus of the rat brain.

  Brain research. Molecular brain research 20041124

• Rate dependence and regulation of action potential and calcium transient in a canine cardiac ventricular cell model.

  Circulation 20041116

• Adenosine inhibits GABAergic and glycinergic transmission in adult rat substantia gelatinosa neurons.

  Journal of neurophysiology 20041101

• Engagement of rat striatal neurons by cortical epileptiform activity investigated with paired recordings.

  Journal of neurophysiology 20041101

• Increased release of serotonin from rat ileum due to dexfenfluramine.

  American journal of physiology. Regulatory, integrative and comparative physiology 20041101

• Ionic mechanisms mediating the myogenic response in newborn porcine cerebral arteries.

  American journal of physiology. Heart and circulatory physiology 20041101

• Volume regulation of mature and immature spermatozoa in a primate model, and possible ion channels involved.

  Human reproduction (Oxford, England) 20041101

• Neuroepithelial oxygen chemoreceptors of the zebrafish gill.

  The Journal of physiology 20041101

• K+ channel blockade impairs remyelination in the cuprizone model.

  Glia 20041101

• Role of potassium channels in the frequency-dependent activity of regenerating nerves.

  Pharmacology 20041101

• Opioid inhibition of GABAergic neurotransmission in mechanically isolated rat periaqueductal gray neurons.

  Neuroscience research 20041101

• Contractile responses of isolated rat mesenteric arteries to acute episodes of severe hypoxia and subsequent reoxygenation.

  Microvascular research 20041101

• Role of K+ channels in M2 muscarinic receptor-mediated inhibition of noradrenaline release from the rat stomach.

  Journal of pharmacological sciences 20041101

• Somatostatin receptors differentially affect spontaneous epileptiform activity in mouse hippocampal slices.

  The European journal of neuroscience 20041101

• Investigation of the mechanism of nicotine-induced relaxation on the sheep sphincter of Oddi.

  Canadian journal of physiology and pharmacology 20041101

• Potassium channel diversity within the muscular components of the feline lower esophageal sphincter.

  Canadian journal of physiology and pharmacology 20041101

• [Determination of trace germanium in coal by spectrophotometry with 2,4-dichlorophenylfluorone].

  Guang pu xue yu guang pu fen xi = Guang pu 20041101

• Enhancement of purinergic neurotransmission by galantamine and other acetylcholinesterase inhibitors in the rat vas deferens.

  European journal of pharmacology 20041025

• Role of IKur in controlling action potential shape and contractility in the human atrium: influence of chronic atrial fibrillation.

  Circulation 20041019

• Sodium-activated potassium conductance participates in the depolarizing afterpotential following a single action potential in rat hippocampal CA1 pyramidal cells.

  Brain research 20041015

• Multi-state, 4-aminopyridine-sensitive ion channels in human spermatozoa.

  Developmental biology 20041015

• Unique roles of SK and Kv4.2 potassium channels in dendritic integration.

  Neuron 20041014

• Arachidonic acid relaxes human pulmonary arteries through K+ channels and nitric oxide pathways.

  European journal of pharmacology 20041006

• Acute relaxation of mouse duodenum [correction of duodenun] by estrogens. Evidence for an estrogen receptor-independent modulation of muscle excitability.

  European journal of pharmacology 20041006

• Differential activation of potassium channels in cerebral and hindquarter arteries of rats during simulated microgravity.

  American journal of physiology. Heart and circulatory physiology 20041001

• The involvement of K(v)3.4 voltage-gated potassium channel in the growth of an oral squamous cell carcinoma cell line.

  Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20041001

• Antispasticity medications: uses and limitations of enteral therapy.

  American journal of physical medicine & rehabilitation 20041001

• Characterization of the voltage-activated currents in cultured atrial myocytes isolated from the heart of the common oyster Crassostrea gigas.

  The Journal of experimental biology 20041001

• Influence of vasostatins, the chromogranin A-derived peptides, on the working heart of the eel (Anguilla anguilla): negative inotropy and mechanism of action.

  General and comparative endocrinology 20041001

• [Endothelium-independent vasorelaxant effect of puerarin on rat thoracic aorta].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20041001

• Stress induces CRF release in the paraventricular nucleus, and both CRF and GABA release in the amygdala.

  Physiology & behavior 20040930

• Effect of the mobile phase on antibody-based enantiomer separations of amino acids in high-performance liquid chromatography.

  Journal of chromatography. A 20040917

• Functional properties of K+ currents in adult mouse ventricular myocytes.

  The Journal of physiology 20040915

• Dopamine inhibits mitral/tufted--> granule cell synapses in the frog olfactory bulb.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20040915

• Oxygen-sensitive Kv channel gene transfer confers oxygen responsiveness to preterm rabbit and remodeled human ductus arteriosus: implications for infants with patent ductus arteriosus.

  Circulation 20040914

• Overexpression of human KCNA5 increases IK V and enhances apoptosis.

  American journal of physiology. Cell physiology 20040901

• Seizure susceptibility to various convulsant stimuli in dystrophin-deficient mdx mice.

  Neuroscience research 20040901

• Visceral periadventitial adipose tissue regulates arterial tone of mesenteric arteries.

  Hypertension (Dallas, Tex. : 1979) 20040901

• Characterization of the ion channel currents in single myocytes of the guinea pig prostate.

  The Journal of urology 20040901

• Zinc inhibits glutamate release via activation of pre-synaptic K channels and reduces ischaemic damage in rat hippocampus.

  Journal of neurochemistry 20040901

• Evidence for a novel K(+) channel modulated by alpha(1A)-adrenoceptors in cardiac myocytes.

  Molecular pharmacology 20040901

• Pharmacological evidence for a key role of voltage-gated K+ channels in the function of rat aortic smooth muscle cells.

  British journal of pharmacology 20040901

• Phase 2 reentry as a trigger to initiate ventricular fibrillation during early acute myocardial ischemia.

  Circulation 20040831

• Upbeat about downbeat nystagmus.

  Neurology 20040824

• Effect of 3,4-diaminopyridine on the gravity dependence of ocular drift in downbeat nystagmus.

  Neurology 20040824

• Preferential expression and function of voltage-gated, O2-sensitive K+ channels in resistance pulmonary arteries explains regional heterogeneity in hypoxic pulmonary vasoconstriction: ionic diversity in smooth muscle cells.

  Circulation research 20040806

• A guinea pig hippocampal slice model of organophosphate-induced seizure activity.

  The Journal of pharmacology and experimental therapeutics 20040801

• KMUP-1, a xanthine derivative, induces relaxation of guinea-pig isolated trachea: the role of the epithelium, cyclic nucleotides and K+ channels.

  British journal of pharmacology 20040801

• Acetylation of raw cotton for oil spill cleanup application: an FTIR and 13C MAS NMR spectroscopic investigation.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20040801

• Effects of local administrations of tempol and diethyldithio-carbamic on peripheral nerve activity.

  Hypertension (Dallas, Tex. : 1979) 20040801

• Properties of Xenopus Kv1.10 channels expressed in HEK293 cells.

  Journal of neurobiology 20040801

• Inactivating and non-inactivating potassium currents in isolated inner hair cells from guinea pig cochlea.

  Acta oto-laryngologica. Supplementum 20040801

• Phasic stimuli evoke precisely timed spikes in intermittently discharging mitral cells.

  Journal of neurophysiology 20040801

• Fatigue in multiple sclerosis: multidimensional assessment and response to symptomatic treatment.

  Multiple sclerosis (Houndmills, Basingstoke, England) 20040801

• Regulation by equilibrative nucleoside transporter of adenosine outward currents in adult rat spinal dorsal horn neurons.

  Brain research bulletin 20040730

• Acquired dendritic channelopathy in temporal lobe epilepsy.

  Science (New York, N.Y.) 20040723

• K(+) channel activity and redox status are differentially required for JNK activation by UV and reactive oxygen species.

  Experimental cell research 20040715

• Substance P induces inward current and regulates pacemaker currents through tachykinin NK1 receptor in cultured interstitial cells of Cajal of murine small intestine.

  European journal of pharmacology 20040708

• Functional expression of TRESK-2, a new member of the tandem-pore K+ channel family.

  The Journal of biological chemistry 20040702

• Involvement of anion channel(s) in the modulation of the transient outward K(+) channel in rat ventricular myocytes.

  American journal of physiology. Cell physiology 20040701

• KW-7158 [(2S)-(+)-3,3,3-trifluoro-2-hydroxy-2-methyl-N-(5,5,10-trioxo-4,10-dihydrothieno[3,2-c][1]benzothiepin-9-yl)propanamide] enhances A-type K+ currents in neurons of the dorsal root ganglion of the adult rat.

  The Journal of pharmacology and experimental therapeutics 20040701

• GABAA receptor-dependent synchronization leads to ictogenesis in the human dysplastic cortex.

  Brain : a journal of neurology 20040701

• 'Low' concentrations of sodium fluoride inhibit neurotransmitter release from the guinea-pig superior cervical ganglion.

  Neuroscience letters 20040701

• Adenosine A2A receptor blockade differentially influences excitotoxic mechanisms at pre- and postsynaptic sites in the rat striatum.

  Journal of neuroscience research 20040701

• Intracellular calcium increase in epileptiform activity: modulation by levetiracetam and lamotrigine.

  Epilepsia 20040701

• Inhibitory effect of lamotrigine on A-type potassium current in hippocampal neuron-derived H19-7 cells.

  Epilepsia 20040701

• Quantitative effects produced by modifications of neuronal activity on the size of GABAA receptor clusters in hippocampal slice cultures.

  The European journal of neuroscience 20040701

• 1-[(4-Chlorobenzoyl)methyl]-4-(N,N-dimethylamino)pyridinium bromide sesquihydrate and 1-[(4-bromobenzoyl)methyl]-4-(N,N-dimethylamino)pyridinium bromide sesquihydrate.

  Acta crystallographica. Section C, Crystal structure communications 20040701

• Role of sodium and calcium channel block in unmasking the Brugada syndrome.

  Heart rhythm 20040701

• Study of the involvement of K+ channels in the peripheral antinociception of the kappa-opioid receptor agonist bremazocine.

  European journal of pharmacology 20040628

• Protective cap over CA1 synapses: extrasynaptic glutamate does not reach the postsynaptic density.

  Brain research 20040618

• Changes in electrophysiological properties of regenerating rat peripheral nerves after crush injury.

  Neuroscience letters 20040617

• Determination of A 3,4-diaminopyridine in plasma by liquid chromatography with electrochemical detection using solid-phase extraction.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040615

• Enhanced brain motor activity in patients with MS after a single dose of 3,4-diaminopyridine.

  Neurology 20040608

• Hypoxia-induced inhibition of whole cell membrane currents and ion transport of A549 cells.

  American journal of physiology. Lung cellular and molecular physiology 20040601

• Ca2+-activated K+ channels underlying the impaired acetylcholine-induced vasodilation in 2K-1C hypertensive rats.

  The Journal of pharmacology and experimental therapeutics 20040601

• Noncompetitive metabotropic glutamate5 receptor antagonist (E)-2-methyl-6-styryl-pyridine (SIB1893) depresses glutamate release through inhibition of voltage-dependent Ca2+ entry in rat cerebrocortical nerve terminals (synaptosomes).

  The Journal of pharmacology and experimental therapeutics 20040601

• Distinct phenotypes of congenital acetylcholine receptor deficiency.

  Neuromuscular disorders : NMD 20040601

• Transmembrane action potential heterogeneity in the canine isolated arterially perfused right atrium: effect of IKr and IKur/Ito block.

  American journal of physiology. Heart and circulatory physiology 20040601

• Identification of a Kv3.4 channel in corneal epithelial cells.

  Investigative ophthalmology & visual science 20040601

• Cure of experimental botulism and antibotulismic effect of toosendanin.

  Acta pharmacologica Sinica 20040601

• Investigation of the mechanism of nicotine induced relaxation in rabbit corpus cavernosum in vitro.

  Urological research 20040601

• Combination of variable frequency train stimulation and K+ channel blockade to augment skeletal muscle force.

  IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society 20040601

• Intestinal zinc uptake in freshwater rainbow trout: evidence for apical pathways associated with potassium efflux and modified by calcium.

  Biochimica et biophysica acta 20040527

• Input resistance is voltage dependent due to activation of Ih channels in rat CA1 pyramidal cells.

  Journal of neuroscience research 20040515

• Treatment of episodic ataxia type 2 with the potassium channel blocker 4-aminopyridine.

  Neurology 20040511

• Electrophysiological and morphological characterization of identified motor neurons in the Drosophila third instar larva central nervous system.

  Journal of neurophysiology 20040501

• Nifedipine affects the anticonvulsant activity of topiramate in various animal models of epilepsy.

  Neuropharmacology 20040501

• Vascular relaxation response to hydrogen peroxide is impaired in hypertension.

  British journal of pharmacology 20040501

• Effect of 4-aminopyridine on synaptic transmission in rat hippocampal slices.

  Brain research 20040501

• 4-Aminopyridine-induced epileptogenesis depends on activation of mitogen-activated protein kinase ERK.

  Journal of neurochemistry 20040501

• Orexigen-sensitive NPY/AgRP pacemaker neurons in the hypothalamic arcuate nucleus.

  Nature neuroscience 20040501

• Valproate reduced synaptic activity increase induced by 4-aminopyridine at the hippocampal CA3-CA1 synapse.

  Epilepsia 20040501

• Sevoflurane depolarizes pre-synaptic mitochondria in the central nervous system.

  Acta anaesthesiologica Scandinavica 20040501

• Detection of glutamate in optically trapped single nerve terminals by Raman spectroscopy.

  Analytical chemistry 20040501

• Calibration-free estimates of batch process yields and detection of process upsets using in situ spectroscopic measurements and nonisothermal kinetic models: 4-(dimethylamino)pyridine- catalyzed esterification of butanol.

  Analytical chemistry 20040501

• Effects of acetazolamide and 4-aminopyridine on CO2-induced slowly adapting pulmonary stretch receptor inhibition in rats.

  Chemical senses 20040501

• Khellinone derivatives as blockers of the voltage-gated potassium channel Kv1.3: synthesis and immunosuppressive activity.

  Journal of medicinal chemistry 20040422

• Resonantly enhanced two photon ionization and zero kinetic energy spectroscopy of jet-cooled 4-aminopyridine.

  The Journal of chemical physics 20040422

• Fabrication of temperature-sensitive imprinted polymer hydrogel.

  Macromolecular bioscience 20040419

• Synthesis of sequential polydepsipeptides utilizing a new approach for the synthesis of depsipeptides.

  Biopolymers 20040415

• 4-aminopyridine improves downbeat nystagmus, smooth pursuit, and VOR gain.

  Neurology 20040413

• Diclofenac-induced peripheral antinociception is associated with ATP-sensitive K+ channels activation.

  Life sciences 20040402

• Gastric ulcers reduce A-type potassium currents in rat gastric sensory ganglion neurons.

  American journal of physiology. Gastrointestinal and liver physiology 20040401

• A voltage-gated K(+) current in renal inner medullary collecting duct cells.

  American journal of physiology. Cell physiology 20040401

• Potassium channel dysfunction in cerebral arteries of insulin-resistant rats is mediated by reactive oxygen species.

  Stroke 20040401

• Chromogranin A N-terminal fragments vasostatin-1 and the synthetic CGA 7-57 peptide act as cardiostatins on the isolated working frog heart.

  General and comparative endocrinology 20040401

• K(+) currents produce P(1) in the RW CAP: evidence from DC current bias, K(+) channel blockade and recordings from cochlea and brainstem.

  Hearing research 20040401

• Demonstration of calcium-activated transient outward chloride current and delayed rectifier potassium currents in Swine atrial myocytes.

  Journal of molecular and cellular cardiology 20040401

• High-fat diet alters K+-currents in porcine coronary arteries and adenosine sensitivity during metabolic inhibition.

  Journal of cardiovascular pharmacology 20040401

• Inhibition of transient K+ current by copper in Drosophila neurons.

  Neurochemical research 20040401

• Seizure susceptibility to various convulsant stimuli of knockout interleukin-6 mice.

  Pharmacology, biochemistry, and behavior 20040401

• Electrical heterogeneity of canine right ventricular transient outward potassium currents.

  Chinese medical journal 20040401

• Studying cardiac arrhythmias in the mouse--a reasonable model for probing mechanisms?

  Trends in cardiovascular medicine 20040401

• Effect of blockers of potential-dependent and calcium-activated K+-channels on facilitation of neuromuscular transmission.

  Bulletin of experimental biology and medicine 20040401

• [Synthesis and spectral properties of tailed sercine tetraphenylporphyrin cobalt complex].

  Guang pu xue yu guang pu fen xi = Guang pu 20040401

• Characterization of a fast transient outward current in neocortical neurons from epilepsy patients.

  Journal of neuroscience research 20040315

• Periodic orbit analysis reveals subtle effects of atropine on epileptiform activity in the guinea-pig hippocampal slice.

  Neuroscience letters 20040311

• Regulation of myometrial phospholipase C system and uterine contraction by beta-adrenergic receptors in midpregnant rat.

  Biology of reproduction 20040301

• Potassium currents regulating secretion from Brunner's glands in guinea pig duodenum.

  American journal of physiology. Gastrointestinal and liver physiology 20040301

• Amyloid beta-protein fragment 31-35 suppresses delayed rectifying potassium channels in membrane patches excised from hippocampal neurons in rats.

  Synapse (New York, N.Y.) 20040301

• Protection against cocaine toxicity in mice by the dopamine D3/D2 agonist R-(+)-trans-3,4a,10b-tetrahydro-4-propyl-2H,5H-[1]benzopyrano[4,3-b]-1,4-oxazin-9-ol [(+)-PD 128,907].

  The Journal of pharmacology and experimental therapeutics 20040301

• The role of bradykinin, AT2 and angiotensin 1-7 receptors in the EDRF-dependent vasodilator effect of angiotensin II on the isolated mesenteric vascular bed of the rat.

  British journal of pharmacology 20040301

• Kynurenic acid production in cultured bovine aortic endothelial cells. Homocysteine is a potent inhibitor.

  Naunyn-Schmiedeberg's archives of pharmacology 20040301

• The sleep lipid oleamide may represent an endogenous anticonvulsant: an in vitro comparative study in the 4-aminopyridine rat brain-slice model.

  Neuropharmacology 20040301

• Blunted effect of the Kv channel inhibitor on pulmonary circulation in Tibetan sheep: a model for studying hypoxia and pulmonary artery pressure regulation.

  Respirology (Carlton, Vic.) 20040301

• Novel truncating RAPSN mutations causing congenital myasthenic syndrome responsive to 3,4-diaminopyridine.

  Neuromuscular disorders : NMD 20040301

• PACAP inhibits delayed rectifier potassium current via a cAMP/PKA transduction pathway: evidence for the involvement of I k in the anti-apoptotic action of PACAP.

  The European journal of neuroscience 20040301

• Anticonvulsant activity of the testosterone-derived neurosteroid 3alpha-androstanediol.

  Neuroreport 20040301

• Nitric oxide decreases a calcium-activated potassium current via activation of phosphodiesterase 2 in Helix U-cells.

  Brain research 20040227

• Morphine inhibits glutamate exocytosis from rat cerebral cortex nerve terminals (synaptosomes) by reducing Ca2+ influx.

  Synapse (New York, N.Y.) 20040201

• Attenuation by 4-aminopyridine of delayed vasorelaxation by troglitazone.

  Metabolism: clinical and experimental 20040201

• Inhibition of ultra-rapid delayed rectifier K+ current by verapamil in human atrial myocytes.

  Journal of molecular and cellular cardiology 20040201

• Isosteviol as a potassium channel opener to lower intracellular calcium concentrations in cultured aortic smooth muscle cells.

  Planta medica 20040201

• Characterization of the participation of sodium channels on the rise in Na+ induced by 4-aminopyridine (4-AP) in synaptosomes.

  Neurochemical research 20040201

• Lambert-Eaton myasthenic syndrome.

  Revue neurologique 20040201

• K+ channels in cardiomyocytes of the pulmonate snail helix.

  The Journal of membrane biology 20040201

• [High throughput screening method of potassium channel regulators].

  Yao xue xue bao = Acta pharmaceutica Sinica 20040201

• Biophysical properties and metabolic regulation of a TASK-like potassium channel in rat carotid body type 1 cells.

  American journal of physiology. Lung cellular and molecular physiology 20040101

• GABA(B) receptor activation and limbic network ictogenesis.

  Neuropharmacology 20040101

• The possible role of myelin destruction as a precipitating event in Alzheimer's disease.

  Neurobiology of aging 20040101

• Attenuation of I(K,slow1) and I(K,slow2) in Kv1/Kv2DN mice prolongs APD and QT intervals but does not suppress spontaneous or inducible arrhythmias.

  American journal of physiology. Heart and circulatory physiology 20040101

• 1H NMR studies on molecular motions of 4-aminopyridinium and pyrrolidinium cations in new ferroics.

  Solid state nuclear magnetic resonance 20040101

• Activaton of GABAB receptor inhibits the excitability of rat small diameter trigeminal root ganglion neurons.

  Neuroscience 20040101

• Comparative anticonvulsant activity of N-acetyl-1-aryl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline derivatives in rodents.

  Pharmacology, biochemistry, and behavior 20040101

• Initiation of electrographic seizures by neuronal networks in entorhinal and perirhinal cortices in vitro.

  Neuroscience 20040101

• Pharmacokinetics and safety of multiple oral doses of sustained-release 4-aminopyridine (Fampridine-SR) in subjects with chronic, incomplete spinal cord injury.

  Archives of physical medicine and rehabilitation 20040101

• Differential alterations of receptor densities of three muscarinic acetylcholine receptor subtypes and current densities of the corresponding K+ channels in canine atria with atrial fibrillation induced by experimental congestive heart failure.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20040101

• Electrophysiologic changes in the lateral and basal amygdaloid nuclei in temporal lobe epilepsy: an in vitro study in epileptic rats.

  Neuroscience 20040101

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20040101

• Histamine activates a background, arachidonic acid-sensitive K channel in embryonic chick dorsal root ganglion neurons.

  Neuroscience 20040101

• Mechanisms underlying the riluzole inhibition of glutamate release from rat cerebral cortex nerve terminals (synaptosomes).

  Neuroscience 20040101

• 4-Aminopyridine activates calcium influx through modulation of the pore-forming purinergic receptor in human peripheral blood mononuclear cells.

  Canadian journal of physiology and pharmacology 20040101

• A Ca2+-independent slow afterhyperpolarization in substantia nigra compacta neurons.

  Neuroscience 20040101

• Opioidergic modulation of excitability of rat trigeminal root ganglion neuron projections to the superficial layer of cervical dorsal horn.

  Neuroscience 20040101

• Characterization of the actions of AvTx 7 isolated from Agelaia vicina (Hymenoptera: Vespidae) wasp venom on synaptosomal glutamate uptake and release.

  Journal of biochemical and molecular toxicology 20040101

• [Inhibition of voltage-gated K+ current in rat intrapulmonary arterial smooth muscle cells by endothelin-1].

  Yao xue xue bao = Acta pharmaceutica Sinica 20040101

• Influence of enteric-coated lactose on the release profile of 4-aminopyridine from HPMC matrix tablets.

  Pharmaceutical development and technology 20040101

• Low micromolar concentrations of 4-aminopyridine facilitate fictive locomotion expressed by the rat spinal cord in vitro.

  Neuroscience 20040101

• Effects of potassium and anion channel blockers on the cellular response of human osteoarthritic chondrocytes.

  Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 20040101

• A potential role for astrocytes in mediating the antiepileptic actions of furosemide in vitro.

  Neuroscience 20040101

• Aspartate release from rat hippocampal synaptosomes.

  Neuroscience 20040101

• Depolarization-activated K+ currents of the bushy neurones of the rat cochlear nucleus in a thin brain slice preparation.

  Acta physiologica Hungarica 20040101

• In vivo properties of potassium channels in cerebral blood vessels during diabetes mellitus.

  Microcirculation (New York, N.Y. : 1994) 20040101

• Uterine extracellular matrix components are altered during defective decidualization in interleukin-11 receptor alpha deficient mice.

  Reproductive biology and endocrinology : RB&E 20040101

• The use of 4-aminopyridine (fampridine) in demyelinating disorders.

  CNS drug reviews 20040101

• [Possible role of ammonium as a paracrine regulator in the uterine tissue].

  Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20040101

• Modulation by 4-aminopyridine and calcium on the effect of adenosine on isolated spontaneously beating rat atria.

  Journal of basic and clinical physiology and pharmacology 20040101

• Osborn waves: history and significance.

  Indian pacing and electrophysiology journal 20040101

• Endothelium-independent vasorelaxant effect of puerarin on rat thoracic aorta.

  Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference 20040101

• Testosterone causes simultaneous decrease of [Ca2+]I and tension in rabbit coronary arteries: by opening voltage dependent potassium channels.

  Yonsei medical journal 20031230

• Manipulating transmitter release at the neuromuscular junction of neonatal rats alters the expression of ChAT and GAP-43 in motoneurons.

  Brain research. Developmental brain research 20031219

• 3,4-DAP-evoked transmitter release in hippocampal slices of aged rats with impaired memory.

  Brain research bulletin 20031215

• Pentose phosphate pathway coordinates multiple redox-controlled relaxing mechanisms in bovine coronary arteries.

  American journal of physiology. Heart and circulatory physiology 20031201

• Catalase has negligible inhibitory effects on endothelium-dependent relaxations in mouse isolated aorta and small mesenteric artery.

  British journal of pharmacology 20031201

• Multiple effects of mefenamic acid on K(+) currents in smooth muscle cells from pig proximal urethra.

  British journal of pharmacology 20031201

• Presynaptic group I metabotropic glutamate receptors modulate synaptic transmission in the rat superior colliculus via 4-AP sensitive K(+) channels.

  British journal of pharmacology 20031201

• Ion-channel currents of smooth muscle cells isolated from the prostate of guinea-pig.

  BJU international 20031201

• Long-lasting anticonvulsant effect of focal cooling on experimental neocortical seizures.

  Epilepsia 20031201

• Involvement of gap junctions in the manifestation and control of the duration of seizures in rats in vivo.

  Epilepsia 20031201

• UV-induced corneal epithelial cell death by activation of potassium channels.

  Investigative ophthalmology & visual science 20031201

• Cultivation in rotating bioreactors promotes maintenance of cardiac myocyte electrophysiology and molecular properties.

  Tissue engineering 20031201

• On the photobiological properties of chimeras combining quaternary ammonium derivatives of retinoic amides and psoralen. A study with cultured human keratinocytes.

  Photochemistry and photobiology 20031201

• [Thyroliberin blocks potassium A-current in neurons of the respiratory center of adult rats in vitro].

  Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20031201

• Mechanisms contributing to the exacerbated epileptiform activity in hippocampal slices of GABAB1 receptor subunit knockout mice.

  Epilepsy research 20031201

• Endothelium-dependent vasorelaxant effects of the aqueous extracts of the Eucommia ulmoides Oliv. leaf and bark: implications on their antihypertensive action.

  Vascular pharmacology 20031201

• Cyclopentyladenosine and some of its low-efficacy derivatives inhibit striatal synaptosomal release of acetylcholine to a similar degree.

  European journal of pharmacology 20031128

• Heterogeneous Baylis-Hillman using a polystyrene-bound 4-(N-benzyl-N-methylamino)pyridine as reusable catalyst.

  Chemical communications (Cambridge, England) 20031121

• Two-pore domain K channel, TASK-1, in pulmonary artery smooth muscle cells.

  Circulation research 20031114

• Distinct roles of Kv1 and Kv3 potassium channels at the calyx of Held presynaptic terminal.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20031112

• Regulation of granule cell excitability by a low-threshold calcium spike in turtle olfactory bulb.

  Journal of neurophysiology 20031101

• Comparison of time- and voltage-dependent K+ currents in myocytes from left and right atria of adult mice.

  American journal of physiology. Heart and circulatory physiology 20031101

• Regional and frequency-dependent changes in action potentials and transient outward K+ currents in ventricular myocytes from J-2-K cardiomyopathic hamsters.

  Basic research in cardiology 20031101

• Mesenteric lymph from rats with thermal injury prolongs the action potential and increases Ca2+ transient in rat ventricular myocytes.

  Shock (Augusta, Ga.) 20031101

• Distinct quantal features of AMPA and NMDA synaptic currents in hippocampal neurons: implication of glutamate spillover and receptor saturation.

  Biophysical journal 20031101

• The increase of voltage-gated potassium channel Kv3.4 mRNA expression in oral squamous cell carcinoma.

  Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20031101

• Valproate suppresses status epilepticus induced by 4-aminopyridine in CA1 hippocampus region.

  Epilepsia 20031101

• [Formulation and stability of hospital preparation of 3,4-diaminopyridine capsules].

  Annales pharmaceutiques francaises 20031101

• Synaptic and non-synaptic mechanisms of amygdala recruitment into temporolimbic epileptiform activities.

  The European journal of neuroscience 20031101

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20031101

• Modulation of rabbit corneal epithelial cell proliferation by growth factor-regulated K(+) channel activity.

  The Journal of membrane biology 20031101

• [beta-adrenoceptor subtypes involved in relaxations of guinea-pig gastrointestinal smooth muscles: distribution and signaling pathway of beta 3-adrenoceptors].

  Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20031101

• Ca2+-activated K+ (BK) channel inactivation contributes to spike broadening during repetitive firing in the rat lateral amygdala.

  The Journal of physiology 20031015

• An ID-like current that is downregulated by Ca2+ modulates information coding at CA3-CA3 synapses in the rat hippocampus.

  The Journal of physiology 20031015

• Biophysical properties and ionic signature of neuronal progenitors of the postnatal subventricular zone in situ.

  Journal of neurophysiology 20031001

• Sternohyoid muscle fatigue properties of dy/dy dystrophic mice, an animal model of merosin-deficient congenital muscular dystrophy.

  Pediatric research 20031001

• Effects of 4-aminopyridine on stretched mammalian spinal cord: the role of potassium channels in axonal conduction.

  Journal of neurophysiology 20031001

• Non-contractile cells with thin processes resembling interstitial cells of Cajal found in the wall of guinea-pig mesenteric arteries.

  The Journal of physiology 20031001

• SR141716A-sensitive enhancement of ET-1 hypotensive effect by chronic NOS inhibition.

  Hypertension (Dallas, Tex. : 1979) 20031001

• Differential effects of lidocaine and tramadol on modified nerve impulse by 4-aminopyridine in rats.

  Pharmacology 20031001

• 4-aminopyridine transiently increases intraocular pressure in rabbits.

  Pharmacology 20031001

• Expression of heat shock protein 70 induced by 4-aminopyridine through glutamate-mediated excitotoxic stress in rat hippocampus in vivo.

  Neuropharmacology 20031001

• Reduction of voltage-operated potassium currents by levetiracetam: a novel antiepileptic mechanism of action?

  Neuropharmacology 20031001

• The cholinomimetic agent bethanechol activates IK(ACh) in feline atrial myocytes.

  Naunyn-Schmiedeberg's archives of pharmacology 20031001

• Amitriptyline eliminates calculi through urinary tract smooth muscle relaxation.

  Kidney international 20031001

• Cerebrovascular vasodilation to extraluminal acidosis occurs via combined activation of ATP-sensitive and Ca2+-activated potassium channels.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20031001

• Differential thermosensitivity of sensory neurons in the guinea pig trigeminal ganglion.

  Journal of neurophysiology 20031001

• Inhibitory effects of potassium channel blockers on carbachol-induced contraction in rat detrusor muscle.

  Journal of Korean medical science 20031001

• Endothelium-dependent relaxation of canine uterine artery in response to acetylcholine: the possible involvement of alternative pathways.

  Journal of veterinary medicine. A, Physiology, pathology, clinical medicine 20031001

• Functional properties of four splice variants of a human pancreatic tandem-pore K+ channel, TALK-1.

  American journal of physiology. Cell physiology 20030901

• Use-dependent shift from inhibitory to excitatory GABAA receptor action in SP-O interneurons in the rat hippocampal CA3 area.

  Journal of neurophysiology 20030901

• Elevated glucose impairs cAMP-mediated dilation by reducing Kv channel activity in rat small coronary smooth muscle cells.

  American journal of physiology. Heart and circulatory physiology 20030901

• Physiological regulation of Munc18/nSec1 phosphorylation on serine-313.

  Journal of neurochemistry 20030901

• Synthesis and characterization of materials containing arrays of decavanadate clusters.

  Frontiers in bioscience : a journal and virtual library 20030901

• K+ channels in cultured bovine retinal pericytes: effects of beta-adrenergic stimulation.

  Journal of cardiovascular pharmacology 20030901

• Electrical properties of detrusor smooth muscles from the pig and human urinary bladder.

  British journal of pharmacology 20030901

• Ionic basis for the regulation of spontaneous excitation in detrusor smooth muscle cells of the guinea-pig urinary bladder.

  British journal of pharmacology 20030901

• Potassium channels in human umbilical artery cells.

  Journal of the Society for Gynecologic Investigation 20030901

• Epileptiform activity in rat spinal dorsal horn in vitro has common features with neuropathic pain.

  Pain 20030901

• Regulation of epileptiform activity in hippocampus by nicotinic acetylcholine receptor activation.

  Epilepsy research 20030901

• Epileptiform synchronization in the human dysplastic cortex.

  Epileptic disorders : international epilepsy journal with videotape 20030901

• Long-term restitution of 4-aminopyridine-sensitive currents in Kv1DN ventricular myocytes using adeno-associated virus-mediated delivery of Kv1.5.

  FEBS letters 20030828

• [Comparison of the electrophysiological features between the rhythmic cells of the aortic vestibule and the sinoatrial node in the rabbit].

  Sheng li xue bao : [Acta physiologica Sinica] 20030825

• Mechanisms of vasorelaxation to 17beta-oestradiol in rat arteries.

  European journal of pharmacology 20030822

• A role for Src kinase in the regulation of glutamate release from rat cerebrocortical nerve terminals.

  Neuroreport 20030806

• Developmental differences in Ca2+-activated K+ channel activity in ovine basilar artery.

  American journal of physiology. Heart and circulatory physiology 20030801

• Wheel-running exercise alters rat diaphragm action potentials and their regulation by K+ channels.

  Journal of applied physiology (Bethesda, Md. : 1985) 20030801

• Is the interaction between felbamate and valproate against seizures induced by 4-aminopyridine and pentylenetetrazole in mice beneficial?

  Pharmacological research 20030801

• Predominant expression of Kv1.3 voltage-gated K+ channel subunit in rat prostate cancer cell lines: electrophysiological, pharmacological and molecular characterisation.

  Pflugers Archiv : European journal of physiology 20030801

• Spike-dependent intrinsic plasticity increases firing probability in rat striatal neurons in vivo.

  The Journal of physiology 20030801

• The role of K+ channels in vasorelaxation induced by hypoxia and the modulator effects of lidocaine in the rat carotid artery.

  Anesthesia and analgesia 20030801

• Ca2+-activated K+ channels in the endothelial cell layer involved in modulation of neurogenic contractions in rat penile arteries.

  European journal of pharmacology 20030801

• [Changes of potassium channel activity of hindlimb arterial smooth muscle cells in tail-suspended rats].

  Hang tian yi xue yu yi xue gong cheng = Space medicine & medical engineering 20030801

• Sialic acid contributes to generation of ectopic spontaneous discharges in rats with neuropathic pain.

  Neuroscience letters 20030731

• Protein kinase C inhibits the transplasma membrane influx of Ca2+ triggered by 4-aminopyridine in Jurkat T lymphocytes.

  Biochimica et biophysica acta 20030723

• Potassium channels, the cerebellum, and treatment for downbeat nystagmus.

  Neurology 20030722

• Treatment of downbeat nystagmus with 3,4-diaminopyridine: a placebo-controlled study.

  Neurology 20030722

• Differences in the mechanisms for relaxation of aorta induced by 17beta-estradiol or progesterone between normotensive and hypertensive rats.

  European journal of pharmacology 20030704

• Carbon isosteres of the 4-aminopyridine substructure of chloroquine: effects on pK(a), hematin binding, inhibition of hemozoin formation, and parasite growth.

  Journal of medicinal chemistry 20030703

• Properties and functional role of voltage-dependent potassium channels in dendrites of rat cerebellar Purkinje neurons.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20030702

• In vivo gene transfer of Kv1.5 normalizes action potential duration and shortens QT interval in mice with long QT phenotype.

  American journal of physiology. Heart and circulatory physiology 20030701

• In vitro relaxation of vascular smooth muscle by atropine: involvement of K+ channels and endothelium.

  Naunyn-Schmiedeberg's archives of pharmacology 20030701

• The effect of isoflurane and sevoflurane on cerebrocortical presynaptic Ca2+ and protein kinase C activity.

  Journal of neurosurgical anesthesiology 20030701

• Acute vasodilator effects of HMG-CoA reductase inhibitors: involvement of PI3-kinase/Akt pathway and Kv channels.

  Journal of cardiovascular pharmacology 20030701

• Delayed rectifier K currents in NF1 Schwann cells. Pharmacological block inhibits proliferation.

  Neurobiology of disease 20030701

• Fully automated synthesis module for preparation of S-(2-[(18)F]fluoroethyl)-L-methionine by direct nucleophilic exchange on a quaternary 4-aminopyridinium resin.

  Nuclear medicine and biology 20030701

• 4-Aminopyridine inhibits the neuromuscular effects of nitric oxide and 8-Br-cGMP.

  Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20030701

• Postdecentralization plasticity of voltage-gated K+ currents in glandular sympathetic neurons in rats.

  The European journal of neuroscience 20030701

• Efficacy and safety of 4-aminopyridine in patients with long-term spinal cord injury: a randomized, double-blind, placebo-controlled trial.

  Pharmacotherapy 20030701

• Use-dependent removal of the 4-aminopyridine-induced block of the transient K+ current in rat dorsal root ganglia.

  Journal of pharmacological sciences 20030701

• Continuous monitoring of intracerebral glutamate levels in awake monkeys using microdialysis and enzyme fluorometric detection.

  Journal of neuroscience methods 20030630

• Fluoxetine depresses glutamate exocytosis in the rat cerebrocortical nerve terminals (synaptosomes) via inhibition of P/Q-type Ca2+ channels.

  Synapse (New York, N.Y.) 20030615

• Inhibition of HERG K+ current and prolongation of the guinea-pig ventricular action potential by 4-aminopyridine.

  The Journal of physiology 20030615

• Phenylarsine oxide inhibits alpha-latrotoxin-stimulated [3H]GABA release from rat brain synaptosomes.

  Neurochemistry international 20030601

• Comparison of potassium currents in human decidua before and after the onset of labor.

  Biology of reproduction 20030601

• Insulin-like growth factor I modifies electrophysiological properties of rat brain stem neurons.

  Journal of neurophysiology 20030601

• Vasodilatory and electrophysiological actions of 8-iso-prostaglandin E2 in porcine coronary artery.

  The Journal of pharmacology and experimental therapeutics 20030601

• Actions of the sodium channel inhibitor 202W92 on rat midbrain dopaminergic neurons.

  Synapse (New York, N.Y.) 20030601

• Voltage-gated potassium currents in rat vas deferens smooth muscle cells.

  Pflugers Archiv : European journal of physiology 20030601

• Apoptosis repressor with caspase domain inhibits cardiomyocyte apoptosis by reducing K+ currents.

  American journal of physiology. Cell physiology 20030601

• An important role for the Na+-Ca2+ exchanger in the decrease in cytosolic Ca2+ concentration induced by isoprenaline in the porcine coronary artery.

  The Journal of physiology 20030601

• Sphingosine 1-phosphate and control of vascular tone.

  American journal of physiology. Heart and circulatory physiology 20030601

• NO- activates soluble guanylate cyclase and Kv channels to vasodilate resistance arteries.

  Hypertension (Dallas, Tex. : 1979) 20030601

• Two modes of exocytosis from synaptosomes are differentially regulated by protein phosphatase types 2A and 2B.

  Journal of neurochemistry 20030601

• Differential expression of three distinct potassium currents in the ventral cochlear nucleus.

  Journal of neurophysiology 20030601

• Fully automated synthesis of O-(3-[18F]fluoropropyl)-L-tyrosine by direct nucleophilic exchange on a quaternary 4-aminopyridinium resin.

  Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20030601

• Chronic beta-adrenoceptor blockade and human atrial cell electrophysiology: evidence of pharmacological remodelling.

  Cardiovascular research 20030601

• Kv3.1b is a novel component of CNS nodes.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20030601

• A toxic fraction from scolopendra venom increases the basal release of neurotransmitters in the ventral ganglia of crustaceans.

  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20030601

• Rational modelling of the voltage-dependent K+ channel inactivation by aminopyridines.

  Biophysical chemistry 20030601

• Activation of peripheral ATP-sensitive K+ channels mediates the antinociceptive effect of Crotalus durissus terrificus snake venom.

  European journal of pharmacology 20030523

• Molecular variants of KCNQ channels expressed in murine portal vein myocytes: a role in delayed rectifier current.

  Circulation research 20030516

• Properties and molecular basis of the mouse urinary bladder voltage-gated K+ current.

  The Journal of physiology 20030515

• Effect of varying the restriction degree of 4-aminopyridine release from HPMC matrices on the mechanism controlling the process.

  International journal of pharmaceutics 20030512

• Electrical remodeling in hearts from a calcium-dependent mouse model of hypertrophy and failure: complex nature of K+ current changes and action potential duration.

  Journal of the American College of Cardiology 20030507

• Block of Na+,K+-ATPase and induction of hybrid death by 4-aminopyridine in cultured cortical neurons.

  The Journal of pharmacology and experimental therapeutics 20030501

• A novel O2-sensing mechanism in rat glossopharyngeal neurones mediated by a halothane-inhibitable background K+ conductance.

  The Journal of physiology 20030501

• A correlation between a proteomic evaluation and conventional measurements in the assessment of renal proximal tubular toxicity.

  Toxicological sciences : an official journal of the Society of Toxicology 20030501

• Effects of three different L-type Ca2+ entry blockers on airway constriction induced by muscarinic receptor stimulation.

  British journal of anaesthesia 20030501

• Neurotoxic and myotoxic actions of Naja naja kaouthia venom on skeletal muscle in vitro.

  Toxicon : official journal of the International Society on Toxinology 20030501

• Calcium influx via L- and N-type calcium channels activates a transient large-conductance Ca2+-activated K+ current in mouse neocortical pyramidal neurons.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20030501

• Regulation of backpropagating action potentials in mitral cell lateral dendrites by A-type potassium currents.

  Journal of neurophysiology 20030501

• Calcium channels involved in noradrenaline release from sympathetic neurones in rabbit carotid artery.

  Pharmacology & toxicology 20030501

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20030501

• [Effects of potassium channel blockers on the proliferation of rat bronchial smooth muscle cells].

  Yao xue xue bao = Acta pharmaceutica Sinica 20030501

• The vascular response to the K+ channel inhibitor 4-aminopyridine in hypertensive rats.

  European journal of pharmacology 20030418

• Developmental changes in the expression of potassium currents of embryonic, neonatal and mature mouse inner hair cells.

  The Journal of physiology 20030415

• Circadian variation of cardiac K+ channel gene expression.

  Circulation 20030415

• Cellular uptake of a catechol iron chelator and chloroquine into Plasmodium falciparum infected erythrocytes.

  Biochemical pharmacology 20030415

• Streptozotocin-diabetes alters action potentials in rat diaphragm.

  Respiratory physiology & neurobiology 20030415

• Normalization of Ca2+ signals by small oblique dendrites of CA1 pyramidal neurons.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20030415

• Protein kinase C-epsilon-null mice have decreased hypoxic pulmonary vasoconstriction.

  American journal of physiology. Heart and circulatory physiology 20030401

• Lipid factor (bVLF) from bovine vitreous body evokes in EGFR-T17 cells a Ca2+-dependent K+ current associated with inositol 1,4,5-trisphosphate-independent Ca2+ mobilization.

  Journal of cellular physiology 20030401

• The adenosine inhibition of glutamate exocytosis in synaptosomes is removed by the collapse of the vesicle-cytosol deltapH plus the opening of farnesol-sensitive Ca(2+) channels.

  Cell calcium 20030401

• Calcium-activated transient outward chloride current and phase 1 repolarization of swine ventricular action potential.

  Cardiovascular research 20030401

• The p42/44mitogen-activated protein kinase inhibitor PD 98059, but not U 0126, increases a K+ current in cardiomyocytes.

  Clinical and experimental pharmacology & physiology 20030401

• Dopamine D1-class receptors selectively modulate a slowly inactivating potassium current in rat medial prefrontal cortex pyramidal neurons.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20030401

• GABAC receptors in the rat superior colliculus and pretectum participate in synaptic neurotransmission.

  Journal of neurophysiology 20030401

• Sharp wave-like activity in the hippocampus in vitro in mice lacking the gap junction protein connexin 36.

  Journal of neurophysiology 20030401

• Novel imidazoline compounds that inhibit Kir-mediated vasorelaxation in rat middle cerebral artery.

  Naunyn-Schmiedeberg's archives of pharmacology 20030401

• Voltage-dependent ion channel currents in putative neuroendocrine cells dissociated from the ventral prostate of rat.

  Pflugers Archiv : European journal of physiology 20030401

• Pharmacokinetics of an immediate-release oral formulation of Fampridine (4-aminopyridine) in normal subjects and patients with spinal cord injury.

  Journal of clinical pharmacology 20030401

• Involvement of inwardly rectifying K+ channels in secretory responses of human ileal mucosa.

  The Journal of pharmacy and pharmacology 20030401

• Synergistic interaction between felbamate and lamotrigine against seizures induced by 4-aminopyridine and pentylenetetrazole in mice.

  European journal of pharmacology 20030328

• Mechanisms of vasorelaxation to testosterone in the rat aorta.

  European journal of pharmacology 20030328

• Vibrational spectra, assignments and normal coordinate analysis of 2-amino-5-bromopyridine.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20030315

• Kv3 potassium conductance is necessary and kinetically optimized for high-frequency action potential generation in hippocampal interneurons.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20030315

• Resting potential and submembrane calcium concentration of inner hair cells in the isolated mouse cochlea are set by KCNQ-type potassium channels.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20030315

• Cl- channel blockers inhibit transition of quiescent (G0) fibroblasts into the cell cycle.

  Journal of cellular physiology 20030301

• Selective depression by general anesthetics of glutamate versus GABA release from isolated cortical nerve terminals.

  The Journal of pharmacology and experimental therapeutics 20030301

• Ca2+ current-mediated regulation of action potential by pacing rate in rat ventricular myocytes.

  Cardiovascular research 20030301

• Volatile anesthetics regulate pulmonary vascular tension through different potassium channel subtypes in isolated rabbit lungs.

  Canadian journal of anaesthesia = Journal canadien d'anesthesie 20030301

• Adenosine A1 receptor-mediated presynaptic inhibition of GABAergic transmission in immature rat hippocampal CA1 neurons.

  Journal of neurophysiology 20030301

• Multiple presynaptic and postsynaptic sites of inhibitory modulation by myomodulin at ARC neuromuscular junctions of Aplysia.

  Journal of neurophysiology 20030301

• Metabotropic glutamate receptor activation enhances the activities of two types of Ca2+-activated k+ channels in rat hippocampal astrocytes.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20030301

• A photosensitive vascular smooth muscle store of nitric oxide in mouse aorta: no dependence on expression of endothelial nitric oxide synthase.

  British journal of pharmacology 20030301

• Inhibition of EDHF by two new combinations of K+-channel inhibitors in rat isolated mesenteric arteries.

  British journal of pharmacology 20030301

• Mechanisms of hydrogen-peroxide-induced biphasic response in rat mesenteric artery.

  British journal of pharmacology 20030301

• Group I metabotropic glutamate receptor activation produces prolonged epileptiform neuronal synchronization and alters evoked population responses in the hippocampus.

  Epilepsy research 20030301

• Effects of pentylenetetrazole and 4-aminopyridine on the auditory brainstem response (ABR) and on the hearing sensitivity in the guinea pig in vivo.

  Epilepsy research 20030301

• Investigation of the mechanism of nicotine-induced relaxation in guinea pig gallbladder.

  The Journal of surgical research 20030301

• Gateways to clinical trials. March 2003.

  Methods and findings in experimental and clinical pharmacology 20030301

• Functional role of potassium channels in the vasodilating mechanism of levosimendan in porcine isolated coronary artery.

  Cardiovascular drugs and therapy 20030301

• Effects of acetazolamide and 4-aminoprydine on the responses of deflationary slowly adapting pulmonary stretch receptors to CO2 inhalation in the rat.

  Life sciences 20030227

• Calcium and voltage dependent inactivation of sodium and calcium currents limits calcium influx in Helisoma neurons.

  Journal of neurobiology 20030215

• Non-competitive NMDA receptor antagonists moderate seizure-induced c-fos expression in the rat cerebral cortex.

  Brain research bulletin 20030215

• An endothelium-derived factor modulates purinergic neurotransmission to mesenteric arterial smooth muscle of hamster.

  European journal of pharmacology 20030214

• Is there an A-type K+ current in guinea pig ventricular myocytes?

  American journal of physiology. Heart and circulatory physiology 20030201

• Blockage of voltage-gated K+ channels inhibits adhesion and proliferation of hepatocarcinoma cells.

  International journal of molecular medicine 20030201

• Regional upregulation of Kv2.1-encoded current, IK,slow2, in Kv1DN mice is abolished by crossbreeding with Kv2DN mice.

  American journal of physiology. Heart and circulatory physiology 20030201

• Comparative anticonvulsant activity of some 2,3-benzodiazepine derivatives in rodents.

  Pharmacology, biochemistry, and behavior 20030201

• Role of nitric oxide and K+ channels in relaxation induced by polygodial in rabbit corpus cavernosum in vitro.

  Journal of cardiovascular pharmacology 20030201

• Transient and progressive electrophysiological alterations in the corticostriatal pathway in a mouse model of Huntington's disease.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20030201

• Membrane properties related to the firing behavior of zebrafish motoneurons.

  Journal of neurophysiology 20030201

• TOK homologue in Neurospora crassa: first cloning and functional characterization of an ion channel in a filamentous fungus.

  Eukaryotic cell 20030201

• Effects of 4-aminopyridine on cardiac repolarization, PR interval, and heart rate in patients with spinal cord injury.

  Pharmacotherapy 20030201

• Evidence for the primary role for 4-aminopyridine-sensitive K(v) channels in beta(3)-adrenoceptor-mediated, cyclic AMP-independent relaxations of guinea-pig gastrointestinal smooth muscles.

  Naunyn-Schmiedeberg's archives of pharmacology 20030201

• [Investigation of regulating effects of potassium channels on the tone of rat bronchial smooth muscle].

  Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20030201

• TGF-beta1 induces the expression of fast inactivating K+ (I(A)) channels in rat vascular myofibroblasts.

  Biochemical and biophysical research communications 20030131

• Influence of enteric citric acid on the release profile of 4-aminopyridine from HPMC matrix tablets.

  International journal of pharmaceutics 20030130

• A new strategy for neurochemical photodelivery: metal-ligand heterolytic cleavage.

  Journal of the American Chemical Society 20030129

• Synthesis of starch derivatives with labile cationic groups.

  International journal of biological macromolecules 20030115

• Possible involvement of potassium channels in peripheral antinociception induced by metamizol: lack of participation of ATP-sensitive K+ channels.

  Pharmacology, biochemistry, and behavior 20030101

• Contribution of K+ channels to relaxation induced by 17beta-estradiol but not by progesterone in isolated rat mesenteric artery rings.

  Journal of cardiovascular pharmacology 20030101

• ETA, mixed ETA/ETB receptor antagonists, and protein kinase C inhibitor prevent acute hypoxic pulmonary vasoconstriction: influence of potassium channels.

  Journal of cardiovascular pharmacology 20030101

• Opisthotonic posturing with neuromuscular irritability attributable to 4-aminopyridine ingestion by a healthy pediatric patient.

  Pediatrics 20030101

• Persistent sodium and calcium currents in rat hypoglossal motoneurons.

  Journal of neurophysiology 20030101

• Frog saccular hair cells dissociated with protease VIII exhibit inactivating BK currents, K(V) currents, and low-frequency electrical resonance.

  Hearing research 20030101

• Pharmacology of neuronal background potassium channels.

  Neuropharmacology 20030101

• Presynaptic K+ channel modulation is a crucial ionic basis of neuronal damage induced by ischemia in rat hippocampal CA1 pyramidal neurons.

  Zoological science 20030101

• Molecular mechanisms of glutamate release by bovine chromaffin cells in primary culture.

  Neuroscience 20030101

• Potassium currents in vestibular type II hair cells activated by hydrostatic pressure.

  Neuroscience 20030101

• Metabotropic glutamate and muscarinic cholinergic receptor-mediated preferential inhibition of N-methyl-D-aspartate component of transmissions in rat ventral tegmental area.

  Neuroscience 20030101

• Electrophysiological characterization of cardiac muscarinic acetylcholine receptors: different subtypes mediate different potassium currents.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20030101

• Two distinct effects of cGMP on cytosolic Ca2+ concentration of rat pancreatic beta-cells.

  Journal of pharmacological sciences 20030101

• Potassium channel blockers tetraethylammonium and 4-aminopyridine fail to prevent microglial activation induced by elevated potassium concentration.

  Acta biologica Hungarica 20030101

• Anticonvulsant, sedative and muscle relaxant effects of carbenoxolone in mice.

  BMC pharmacology 20030101

• 4-aminopyridine decreases progesterone production by porcine granulosa cells.

  Reproductive biology and endocrinology : RB&E 20030101

• Endolymphatic sodium homeostasis by Reissner's membrane.

  Neuroscience 20030101

• Voltage-dependent K+ currents in rat cardiac dorsal root ganglion neurons.

  Neuroscience 20030101

• [The role of delayed rectifier potassium channels in the regulation of bronchial smooth muscle tension in asthmatic rats].

  Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20030101

• Treatment for Lambert-Eaton myasthenic syndrome.

  The Cochrane database of systematic reviews 20030101

• Voltage-dependent ebselen and diorganochalcogenides inhibition of 45Ca2+ influx into brain synaptosomes.

  Journal of biochemical and molecular toxicology 20030101

• Structural analysis of oligosaccharides by a combination of electrospray mass spectrometry and bromine isotope tagging of reducing-end sugars with 2-amino-5-bromopyridine.

  Rapid communications in mass spectrometry : RCM 20030101

• Involvement of amygdala networks in epileptiform synchronization in vitro.

  Neuroscience 20030101

• Effect of thymol on kinetic properties of Ca and K currents in rat skeletal muscle.

  BMC pharmacology 20030101

• Pharmacokinetic studies of single and multiple oral doses of fampridine-SR (sustained-release 4-aminopyridine) in patients with chronic spinal cord injury.

  Clinical neuropharmacology 20030101

• Effects of neurosteroids on epileptiform activity induced by picrotoxin and 4-aminopyridine in the rat hippocampal slice.

  Epilepsy research 20030101

• Seizure, neurotransmitter release, and gene expression are closely related in the striatum of 4-aminopyridine-treated rats.

  Epilepsy research 20030101

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20030101

• K+ channels and their effects on membrane potential in rat bronchial smooth muscle cells.

  Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20030101

• Relaxant effect of omeprazole and lansoprazole in guinea pig gallbladder muscle strips in vitro.

  Journal of gastroenterology 20030101

• New treatment methods in verapamil poisoning: experimental studies.

  Polish journal of pharmacology 20030101

• [Severe felodipine and theophylline poisoning successfully treated by 4-aminopyridine: a case report].

  Przeglad lekarski 20030101

• [Successful treatment by 4--aminopyridine of three cases of severe verapamil poisoning].

  Przeglad lekarski 20030101

• The effect of mebudipine and dibudipine, two new Ca2+ channel blockers, in comparison with nifedipine on Ca2+ spikes of F1 neuronal soma membrane in Helix aspersa.

  Acta physiologica Hungarica 20030101

• N-methyl-D-aspartate receptor dependent transcriptional regulation of two calcium/calmodulin-dependent protein kinase type II isoforms in rodent cerebral cortex.

  Neuroscience 20030101

• Transforming growth factor-alpha changes firing properties of developing neocortical GABAergic neurons by down-regulation of voltage-gated potassium currents.

  Neuroscience 20030101

• ACh differentially modulates voltage-gated K channels in glomus cells between DBA/2J and A/J strains of mice.

  Advances in experimental medicine and biology 20030101

• Synthesis, structural characterization and in vitro antitumor activity of 4-dimethylaminopyridinium (6-chloro-1,1-dioxo-1,4,2-benzodithiazin-3-yl)methanides.

  European journal of medicinal chemistry 20030101

• Modulation of action potential firing by iberiotoxin and NS1619 in rat dorsal root ganglion neurons.

  Neuroscience 20030101

• Biophysical properties of Kv3.1 channels in SH-SY5Y human neuroblastoma cells.

  Receptors & channels 20030101

• Cellular and ionic basis for the sex-related difference in the manifestation of the Brugada syndrome and progressive conduction disease phenotypes.

  Journal of electrocardiology 20030101

• O2-sensitive K+ channels in immortalised rat chromaffin-cell-derived MAH cells.

  The Journal of physiology 20021215

• Smooth muscle membrane potential modulates endothelium-dependent relaxation of rat basilar artery via myo-endothelial gap junctions.

  The Journal of physiology 20021215

• Hypoxic fetoplacental vasoconstriction in humans is mediated by potassium channel inhibition.

  American journal of physiology. Heart and circulatory physiology 20021201

• Properties of potassium currents in Purkinje cells of failing human hearts.

  American journal of physiology. Heart and circulatory physiology 20021201

• Epileptiform synchronization and GABA(B) receptor antagonism in the juvenile rat hippocampus.

  The Journal of pharmacology and experimental therapeutics 20021201

• Potassium currents during the action potential of hippocampal CA3 neurons.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20021201

• Intracerebral temperature alterations associated with focal seizures.

  Epilepsy research 20021201

• Masking synchronous GABA-mediated potentials controls limbic seizures.

  Epilepsia 20021201

• 4-aminopyridine- and dendrotoxin-sensitive potassium channels influence excitability of vagal mechano-sensitive endings in guinea-pig oesophagus.

  British journal of pharmacology 20021201

• Presynaptic cross-talk of beta-adrenoreceptor and 5-hydroxytryptamine receptor signalling in the modulation of glutamate release from cerebrocortical nerve terminals.

  British journal of pharmacology 20021201

• Regional analysis of whole cell currents from hair cells of the turtle posterior crista.

  Journal of neurophysiology 20021201

• Ionic currents underlying fast action potentials in the obliquely striated muscle cells of the octopus arm.

  Journal of neurophysiology 20021201

• Characterisation of the ionic currents in freshly isolated rat ureter smooth muscle cells: evidence for species-dependent currents.

  Pflugers Archiv : European journal of physiology 20021201

• Thalamocortical oscillations in a genetic model of absence seizures.

  The European journal of neuroscience 20021201

• New N-pyridinyl(methyl)-indole-2- and 3-(alkyl)carboxamides and derivatives acting as systemic and topical inflammation inhibitors.

  Journal of enzyme inhibition and medicinal chemistry 20021201

• Far field effects of seizure like events induced by application of 4-AP in combined entorhinal cortex hippocampal slices.

  Brain research 20021122

• Neonatal toluene exposure selectively alters sensitivity to different chemoconvulsant drugs in juvenile rats.

  Pharmacology, biochemistry, and behavior 20021101

• The enterins inhibit the contractile activity of the anterior aorta of Aplysia kurodai.

  The Journal of experimental biology 20021101

• Contribution of the K(Ca) channel to membrane potential and O2 sensitivity is decreased in an ovine PPHN model.

  American journal of physiology. Lung cellular and molecular physiology 20021101

• Graded response of K+ current, membrane potential, and [Ca2+]i to hypoxia in pulmonary arterial smooth muscle.

  American journal of physiology. Lung cellular and molecular physiology 20021101

• Dynamical description of sinoatrial node pacemaking: improved mathematical model for primary pacemaker cell.

  American journal of physiology. Heart and circulatory physiology 20021101

• Expression of voltage-gated K+ channels in human atrium.

  Basic research in cardiology 20021101

• The effects of general anesthetics on norepinephrine release from isolated rat cortical nerve terminals.

  Anesthesia and analgesia 20021101

• Ionic currents determining the membrane characteristics of type I spiral ganglion neurons of the guinea pig.

  The European journal of neuroscience 20021101

• [Beta 3-adrenoceptor-mediated relaxation of guinea-pig gastric funds smooth muscle: cAMP-independent characteristics and a primary role of 4-aminopyridine-sensitive voltage-dependent K+ (Kv) channels].

  Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20021101

• Raphé grafts and 3,4-diaminopyridine-evoked overflow of serotonin in the rat hippocampus after 5,7-dihydroxytryptamine lesions: evidence for 5-HT1A autoreceptors.

  Neuroreport 20021028

• Acetylation of rice straw with or without catalysts and its characterization as a natural sorbent in oil spill cleanup.

  Journal of agricultural and food chemistry 20021023

• Exocytotic release of alanine from cultured cerebellar neurons.

  Brain research 20021018

• Synergistic interaction between valproate and lamotrigine against seizures induced by 4-aminopyridine and pentylenetetrazole in mice.

  European journal of pharmacology 20021018

• Characterization of K(+) currents using an in situ patch clamp technique in body wall muscle cells from Caenorhabditis elegans.

  The Journal of physiology 20021015

• Characterization of the A-type potassium current in murine gastric antrum.

  The Journal of physiology 20021015

• Analysis of the pressor response to the K+ channel inhibitor 4-aminopyridine.

  European journal of pharmacology 20021011

• Enzymatic synthesis of dextran-containing hydrogels.

  Biomaterials 20021001

• On the natriuretic effect of verapamil: inhibition of ENaC and transepithelial sodium transport.

  American journal of physiology. Renal physiology 20021001

• The molecular site of action of K(ATP) channel inhibitors determines their ability to inhibit iNOS-mediated relaxation in rat aorta.

  Cardiovascular research 20021001

• A potassium ion channel is involved in cytokine production by activated human macrophages.

  Clinical and experimental immunology 20021001

• Physiological origins of evoked magnetic fields and extracellular field potentials produced by guinea-pig CA3 hippocampal slices.

  The Journal of physiology 20021001

• Role of synaptic metabotropic glutamate receptors in epileptiform discharges in hippocampal slices.

  Journal of neurophysiology 20021001

• Protection of potassium channel inhibitors against hypoxia/reoxygenation-induced death of cultured hippocampal neurons.

  Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20021001

• The peripheral antinociceptive effect of resveratrol is associated with activation of potassium channels.

  Neuropharmacology 20021001

• 15N and 13C NMR study of protonated monoaminopyridines in CDCl3-DMSO.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20021001

• Differential excitability and voltage-dependent Ca2+ signalling in two types of medial entorhinal cortex layer V neurons.

  The European journal of neuroscience 20021001

• Network and pharmacological mechanisms leading to epileptiform synchronization in the limbic system in vitro.

  Progress in neurobiology 20021001

• Facile synthesis of functionalized 4-aminopyridines.

  Chemical communications (Cambridge, England) 20020921

• Differential effects of muscimol upon the firing frequency of large and small amplitude antidromic dorsal root action potentials in rat spinal cord in vitro.

  Neuroscience letters 20020920

• O2 sensing in the human ductus arteriosus: regulation of voltage-gated K+ channels in smooth muscle cells by a mitochondrial redox sensor.

  Circulation research 20020920

• Vanilloid-sensitive afferents activate neurons with prominent A-type potassium currents in nucleus tractus solitarius.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20020915

• Delayed rectifier potassium channels contribute to the depressed pulmonary artery contractility in pneumonia.

  Journal of applied physiology (Bethesda, Md. : 1985) 20020901

• Potential switch from eupnea to fictive gasping after blockade of glycine transmission and potassium channels.

  American journal of physiology. Regulatory, integrative and comparative physiology 20020901

• Voltage- and calcium-activated currents in cultured olfactory receptor neurons of male Mamestra brassicae (Lepidoptera).

  Chemical senses 20020901

• Nitric oxide induces hyperpolarization by opening ATP-sensitive K(+) channels in guinea pig spiral modiolar artery.

  Hearing research 20020901

• A-type potassium currents active at subthreshold potentials in mouse cerebellar Purkinje cells.

  The Journal of physiology 20020901

• Beta 3-adrenoceptor in rat aorta: molecular and biochemical characterization and signalling pathway.

  British journal of pharmacology 20020901

• Micromolar lidocaine selectively blocks propagating ectopic impulses at a distance from their site of origin.

  Pain 20020901

• Presynaptic factors in the regulation of DSI expression in hippocampus.

  Neuropharmacology 20020901

• Sarcoplasmic reticulum K(+) channels from human and sheep atrial cells display a specific electro-pharmacological profile.

  Journal of molecular and cellular cardiology 20020901

• [Delayed rectifier K(+) channel regulated by cyclooxygenase-2 in human gastric cancer cell].

  Zhonghua zhong liu za zhi [Chinese journal of oncology] 20020901

• Preparation of 3,4-diaminopyridine microparticles by solvent-evaporation methods.

  International journal of pharmaceutics 20020821

• Decreased neuronal synchronization during experimental seizures.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20020815

• Comparison of spontaneous and evoked epileptiform activity in three in vitro epilepsy models.

  Brain research 20020802

• Calcium channel subtypes contributing to acetylcholine release from normal, 4-aminopyridine-treated and myasthenic syndrome auto-antibodies-affected neuromuscular junctions.

  British journal of pharmacology 20020801

• Consequences of reduced production of NO on vascular reactivity of porcine coronary arteries after angioplasty: importance of EDHF.

  British journal of pharmacology 20020801

• Coupling of calcium homeostasis to axonal sodium in axons of mouse optic nerve.

  Journal of neurophysiology 20020801

• A Ba(2+)-sensitive K(+) current contributes to the resting membrane potential of neurons in rat suprachiasmatic nucleus.

  Journal of neurophysiology 20020801

• Effects of antiepileptic drugs on induced epileptiform activity in a rat model of dysplasia.

  Epilepsy research 20020801

• Metabotropic glutamate 1 (mGlu1) receptor antagonists enhance GABAergic neurotransmission: a mechanism for the attenuation of post-ischemic injury and epileptiform activity?

  Neuropharmacology 20020801

• Neuroscience. Animal studies raise hopes for spinal cord repair.

  Science (New York, N.Y.) 20020712

• Potassium channels and human corporeal smooth muscle cell tone: diabetes and relaxation of human corpus cavernosum smooth muscle by adenosine triphosphate sensitive potassium channel openers.

  The Journal of urology 20020701

• Chronic carbon monoxide enhanced IbTx-sensitive currents in rat resistance pulmonary artery smooth muscle cells.

  American journal of physiology. Lung cellular and molecular physiology 20020701

• Hypoxic vasorelaxation inhibition by organ culture correlates with loss of Kv channels but not Ca(2+) channels.

  American journal of physiology. Heart and circulatory physiology 20020701

• Presence of a calcium-activated chloride current in mouse ventricular myocytes.

  American journal of physiology. Heart and circulatory physiology 20020701

• Correlation of repolarization of ventricular monophasic action potential with ECG in the murine heart.

  American journal of physiology. Heart and circulatory physiology 20020701

• Relaxant effects of selective phosphodiesterase inhibitors on U46619 precontracted human intralobar pulmonary arteries and role of potassium channels.

  Journal of cardiovascular pharmacology 20020701

• A BK(Ca) to K(v) switch during spermatogenesis in the rat seminiferous tubules.

  Biology of reproduction 20020701

• AMRP peptides modulate a novel K(+) current in pleural sensory neurons of Aplysia.

  Journal of neurophysiology 20020701

• Neocortical potassium currents are enhanced by the antiepileptic drug lamotrigine.

  Epilepsia 20020701

• K+-induced hyperpolarization in rat mesenteric artery: identification, localization and role of Na+/K+-ATPases.

  British journal of pharmacology 20020701

• Improvement of dy/dy dystrophic diaphragm by 3,4-diaminopyridine.

  Muscle & nerve 20020701

• Increased [18F]2-fluoro-2-deoxy-D-glucose ([18F]FDG) yield with recycled target [18O]water: factors affecting the [18F]FDG yield.

  Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20020701

• Ciguatoxin-induced oscillations in membrane potential and action potential firing in rat parasympathetic neurons.

  The European journal of neuroscience 20020701

• Sevoflurane reduces synaptic glutamate release in human synaptosomes.

  Journal of neurosurgical anesthesiology 20020701

• Proconvulsant-induced seizures in alpha(4) nicotinic acetylcholine receptor subunit knockout mice.

  Neuropharmacology 20020701

• Effects of continuous low-dose exposure to organic and inorganic mercury during development on epileptogenicity in rats.

  Neurotoxicology 20020701

• Decreased 4-aminopyridine sensitive K+ currents in endothelial cells from hypertensive rats.

  Hypertension research : official journal of the Japanese Society of Hypertension 20020701

• Low 4-aminopyridine concentration-induced contraction is mediated by neuronal noradrenaline in canine saphenous vein.

  Vascular pharmacology 20020701

• Patch-clamp recordings from white matter glia in thin longitudinal slices of adult rat spinal cord.

  Journal of neuroscience methods 20020630

• Two distinct types of transient outward currents in area postrema neurons in rat brain slices.

  Brain research 20020628

• Spinal cord interneurones labelled transneuronally from the adrenal gland by a GFP-herpes virus construct contain the potassium channel subunit Kv3.1b.

  Autonomic neuroscience : basic & clinical 20020628

• Electromigration dispersion in capillary zone electrophoresis. Experimental validation of use of the Haarhoff-Van der Linde function.

  Journal of chromatography. A 20020614

• Induction of nitric oxide and respiratory burst response in activated goldfish macrophages requires potassium channel activity.

  Developmental and comparative immunology 20020601

• Membrane currents in canine bronchial artery and their regulation by excitatory agonists.

  American journal of physiology. Lung cellular and molecular physiology 20020601

• A 4-AP-sensitive current is enhanced by chronic carbon monoxide exposure in coronary artery myocytes.

  American journal of physiology. Heart and circulatory physiology 20020601

• TNBS ileitis evokes hyperexcitability and changes in ionic membrane properties of nociceptive DRG neurons.

  American journal of physiology. Gastrointestinal and liver physiology 20020601

• Cardiovascular effects of Urtica dioica L. (Urticaceae) roots extracts: in vitro and in vivo pharmacological studies.

  Journal of ethnopharmacology 20020601

• Inactivation and pharmacological properties of sqKv1A homotetramers in Xenopus oocytes cannot account for behavior of the squid 'delayed rectifier' K(+) conductance.

  Biophysical journal 20020601

• Reduction of high-frequency network oscillations (ripples) and pathological network discharges in hippocampal slices from connexin 36-deficient mice.

  The Journal of physiology 20020601

• Phospholipase C-mediated signalling is not required for histamine-induced catecholamine secretion from bovine chromaffin cells.

  Journal of neurochemistry 20020601

• Mechanisms involved in the relaxant action of the ethanolic extract of propolis in the guinea-pig trachea in-vitro.

  The Journal of pharmacy and pharmacology 20020601

• Presynaptic mu-opioid receptors regulate a late step of the secretory process in rat ventral tegmental area GABAergic neurons.

  Neuropharmacology 20020601

• Involvement of ATP-sensitive K(+) channels in the peripheral antinociceptive effect induced by dipyrone.

  European journal of pharmacology 20020524

• Presynaptic modulation of synaptic transmission by opioid receptor in rat subthalamic nucleus in vitro.

  The Journal of physiology 20020515

• Lamina-specific membrane and discharge properties of rat spinal dorsal horn neurones in vitro.

  The Journal of physiology 20020515

• 9-Carboxymethyl-5H,10H-imidazo[1,2-a]indeno[1,2-e]pyrazin-4-one-2-carbocylic acid (RPR117824): selective anticonvulsive and neuroprotective AMPA antagonist.

  Bioorganic & medicinal chemistry 20020501

• Channels involved in transient currents unmasked by removal of extracellular calcium in cardiac cells.

  American journal of physiology. Heart and circulatory physiology 20020501

• Developmental lead exposure differentially alters the susceptibility to chemoconvulsants in rats.

  Toxicology 20020501

• A telencephalic nucleus essential for song learning contains neurons with physiological characteristics of both striatum and globus pallidus.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20020501

• Stimulatory effect of paeoniflorin on the release of noradrenaline from ileal synaptosomes of guinea-pig in-vitro.

  The Journal of pharmacy and pharmacology 20020501

• Paired pulse facilitation is turned into paired pulse depression in hippocampal slices after epilepsy induced by 4-aminopyridine in vivo.

  Neuropharmacology 20020501

• Carbonic anhydrase inhibitor sulthiame reduces intracellular pH and epileptiform activity of hippocampal CA3 neurons.

  Epilepsia 20020501

• [Influence of 4-aminopyridine on voltage-activated K(+) current and cell proliferation in small cell lung cancer].

  Zhonghua zhong liu za zhi [Chinese journal of oncology] 20020501

• Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

  The Journal of biological chemistry 20020419

• The nature of the receptor site for the reversible K+ channel blocking by aminopyridines.

  Biophysical chemistry 20020410

• [Treatment of severe botulism with 3,4-diaminopyridine]].

  Presse medicale (Paris, France : 1983) 20020406

• Does extracellular calcium determine what pool of GABA is the target for alpha-latrotoxin?

  Neurochemistry international 20020401

• Inhibition of glutamate release by fluspirilene in cerebrocortical nerve terminals (synaptosomes).

  Synapse (New York, N.Y.) 20020401

• Determinants of 4-aminopyridine sensitivity in a human brain kv1.4 k(+) channel: phenylalanine substitutions in leucine heptad repeat region stabilize channel closed state.

  Molecular pharmacology 20020401

• Inhibitors of pentose phosphate pathway cause vasodilation: involvement of voltage-gated potassium channels.

  The Journal of pharmacology and experimental therapeutics 20020401

• Effects of haloperidol on K(+) currents in acutely isolated rat retinal ganglion cells.

  Investigative ophthalmology & visual science 20020401

• Synaptically released acetylcholine evokes Ca2+ elevations in astrocytes in hippocampal slices.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20020401

• Control of the propagation of dendritic low-threshold Ca(2+) spikes in Purkinje cells from rat cerebellar slice cultures.

  The Journal of physiology 20020401

• Dopamine selectively reduces GABA(B) transmission onto dopaminergic neurones by an unconventional presynaptic action.

  The Journal of physiology 20020401

• Two-component molecular crystals composed of chloronitrobenzoic acids and 4-aminopyridine.

  Acta crystallographica. Section C, Crystal structure communications 20020401

• Neuropeptide Y increases 4-aminopyridine-sensitive transient outward potassium current in rat ventricular myocytes.

  British journal of pharmacology 20020401

• Effect of halothane on neuronal excitation in the superficial dorsal horn of rat spinal cord slices: evidence for a presynaptic action.

  The European journal of neuroscience 20020401

• Crystal structure of 8-chloroandrographolide triacetate.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20020401

• Effects of anion and cation inhibitors and carbonic anhydrase inhibitors upon the activity of the gypsy moth (Lepidoptera: Lymantriidae) nucleo-polyhedrovirus.

  Journal of economic entomology 20020401

• Glucocorticoid feedback increases the sensitivity of the limbic system to stress.

  Physiology & behavior 20020401

• Developmental changes in the functional characteristics and expression of voltage-gated K+ channel currents in rat aortic myocytes.

  Cardiovascular research 20020401

• 4-Aminopyridine: effects on electrical activity during ischemia and reperfusion in perfused rat hearts.

  Molecular and cellular biochemistry 20020401

• Gateways to Clinical Trials.

  Methods and findings in experimental and clinical pharmacology 20020401

• Functional expression of TREK-2 K+ channel in cultured rat brain astrocytes.

  Brain research 20020322

• Differential effects of remacemide and desglycinyl-remacemide on epileptiform burst firing in the rat hippocampal slice.

  Neuroscience letters 20020315

• ATP dependence of the SNARE/caveolin 1 interaction in the hippocampus.

  Biochemical and biophysical research communications 20020315

• Development of a new photocurable composite resin with reduced curing shrinkage.

  Dental materials : official publication of the Academy of Dental Materials 20020301

• Specificity of cold thermotransduction is determined by differential ionic channel expression.

  Nature neuroscience 20020301

• Inward rectifier K(+) current in human bronchial smooth muscle cells: inhibition with antisense oligonucleotides targeted to Kir2.1 mRNA.

  American journal of respiratory cell and molecular biology 20020301

• Synchronous and asynchronous exocytosis induced by subthreshold high K+ at Cs(+)-loaded terminals of rat hippocampal neurons.

  Journal of neurophysiology 20020301

• Effects of K+ channel blockers on developing rat myelinated CNS axons: identification of four types of K+ channels.

  Journal of neurophysiology 20020301

• Postsynaptic induction and presynaptic expression of group 1 mGluR-dependent LTD in the hippocampal CA1 region.

  Journal of neurophysiology 20020301

• GABA application to hippocampal CA3 or CA1 stratum lacunosum-moleculare excites an interneuron network.

  Journal of neurophysiology 20020301

• Physiological role of calcium-activated potassium currents in the rat lateral amygdala.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20020301

• Hypoxia-induced secretion of serotonin from intact pulmonary neuroepithelial bodies in neonatal rabbit.

  The Journal of physiology 20020301

• Neocortical seizure termination by focal cooling: temperature dependence and automated seizure detection.

  Epilepsia 20020301

• Pharmacological evidence for the activation of K(+) channels by diclofenac.

  European journal of pharmacology 20020301

• Cn11, the first example of a scorpion toxin that is a true blocker of Na(+) currents in crayfish neurons.

  The Journal of experimental biology 20020301

• Reversal of chronic hypoxia-induced alterations in pulmonary artery smooth muscle electromechanical coupling upon air breathing.

  Cardiovascular research 20020301

• A homeostatic mechanism counteracting K(+) -evoked choline release in adult brain.

  Journal of neurochemistry 20020301

• Spinal cord injury medicine. 1. Etiology, classification, and acute medical management.

  Archives of physical medicine and rehabilitation 20020301

• Maturation alters the contribution of potassium channels to resting and 5HT-induced tone in small cerebral arteries of the sheep.

  Brain research. Developmental brain research 20020227

• Formation of molecular ladder elements with macrocyclic platforms via linear bifunctional ligands.

  Inorganic chemistry 20020225

• Mechanism of 4-aminopyridine block of the transient outward K-current in identified Helix neuron.

  Brain research 20020215

• Nitric oxide and convulsions in 4-aminopyridine-treated mice.

  European journal of pharmacology 20020215

• A Shaker homologue encodes an A-type current in Xenopus laevis.

  Brain research 20020208

• Upregulation of Kv 1.4 protein and gene expression after chronic spinal cord injury.

  The Journal of comparative neurology 20020204

• Gender-specific K(+)-channel contribution to adenosine-induced relaxation in coronary arterioles.

  Journal of applied physiology (Bethesda, Md. : 1985) 20020201

• Ion channel diversity in the feline smooth muscle esophagus.

  American journal of physiology. Gastrointestinal and liver physiology 20020201

• Excitatory mechanism of deflationary slowly adapting pulmonary stretch receptors in the rat lung.

  The Journal of pharmacology and experimental therapeutics 20020201

• Novel properties of peptides derived from the sequence coded by exon 26A of human elastin.

  The international journal of biochemistry & cell biology 20020201

• Inhibitory effects of volatile anesthetics on K+ and Cl- channel currents in porcine tracheal and bronchial smooth muscle.

  Anesthesiology 20020201

• Ionic basis of the resting membrane potential and action potential in the pharyngeal muscle of Caenorhabditis elegans.

  Journal of neurophysiology 20020201

• D2 receptors inhibit the secretory process downstream from calcium influx in dopaminergic neurons: implication of K+ channels.

  Journal of neurophysiology 20020201

• Calcium signaling at single mossy fiber presynaptic terminals in the rat hippocampus.

  Journal of neurophysiology 20020201

• Electrophysiologically distinct smooth muscle cell subtypes in rat conduit and resistance pulmonary arteries.

  The Journal of physiology 20020201

• Testosterone-induced vasorelaxation in the rat mesenteric arterial bed is mediated predominantly via potassium channels.

  British journal of pharmacology 20020201

• Properties of voltage dependent potassium currents in acutely isolated rat oculomotor neurons.

  Neuroscience research 20020201

• Inhibition of slow Ca(2+)-activated K(+) current by 4-aminopyridine in rat hippocampal CA1 pyramidal neurones.

  British journal of pharmacology 20020201

• Cytochrome P450-dependent eicosapentaenoic acid metabolites are novel BK channel activators.

  Hypertension (Dallas, Tex. : 1979) 20020201

• Mechanisms modulating estrogen-induced uterine vasodilation.

  Vascular pharmacology 20020201

• Elimination of fast inactivation in Kv4 A-type potassium channels by an auxiliary subunit domain.

  Proceedings of the National Academy of Sciences of the United States of America 20020122

• Gating, modulation and subunit composition of voltage-gated K(+) channels in dendritic inhibitory interneurones of rat hippocampus.

  The Journal of physiology 20020115

• Effects of antiepileptic drugs on afterdischarge generation in rat hippocampal slices.

  Brain research 20020104

• Stimulated increase in free cytosolic Ca(2+) and protein kinase C activity in human cerebrocortical synaptosomes.

  Brain research 20020104

• Determinants of renal microvascular response to ACh: afferent and efferent arteriolar actions of EDHF.

  American journal of physiology. Renal physiology 20020101

• Nitric oxide induces apoptosis by activating K+ channels in pulmonary vascular smooth muscle cells.

  American journal of physiology. Heart and circulatory physiology 20020101

• Molecular basis of voltage-dependent potassium currents in porcine granulosa cells.

  Molecular pharmacology 20020101

• 4-aminopyridine influences heart rate variability in long-standing spinal cord injury.

  American journal of therapeutics 20020101

• A-type potassium currents dominate repolarisation of neonatal rat primary auditory neurones in situ.

  Neuroscience 20020101

• Limbic network interactions leading to hyperexcitability in a model of temporal lobe epilepsy.

  Journal of neurophysiology 20020101

• Multiple mechanisms of vascular smooth muscle relaxation by the activation of proteinase-activated receptor 2 in mouse mesenteric arterioles.

  British journal of pharmacology 20020101

• Presynaptic inhibition of GABAergic miniature currents by metabotropic glutamate receptor in the rat CNS.

  Neuroscience 20020101

• Rate-dependent changes in action potential duration and membrane currents in hamster ventricular myocytes.

  Pflugers Archiv : European journal of physiology 20020101

• Voltage-gated ionic currents in an identified modulatory cell type controlling molluscan feeding.

  The European journal of neuroscience 20020101

• [Morphologic and electrophysiologic characteristics of cultured vestibular ganglia neurons].

  Gaceta medica de Mexico 20020101

• The effect of sevoflurane on glutamate release and uptake in rat cerebrocortical presynaptic terminals.

  Acta anaesthesiologica Scandinavica 20020101

• Pathological changes of isolated spinal cord axons in response to mechanical stretch.

  Neuroscience 20020101

• [Outwardly rectifying potassium currents in isolated outer hair cells in cochlea of guinea pig].

  Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology 20020101

• Laminar properties of 4-aminopyridine-induced synchronous network activities in rat neocortex.

  Neuroscience 20020101

• In vivo and in vitro electrophysiological monitoring of rat neocortical activity after dietary fumonisin exposure.

  Mycopathologia 20020101

• Ca2+ overload evokes a transient outward current in guinea-pig ventricular myocytes.

  Circulation journal : official journal of the Japanese Circulation Society 20020101

• Activation thresholds of K(V), BK andCl(Ca) channels in smooth muscle cells in pial precapillary arterioles.

  Journal of vascular research 20020101

• Influence of ion channels on the proliferation of human chondrocytes.

  Biorheology 20020101

• Relation between potassium-channel kinetics and the intrinsic dynamics in isolated retinal bipolar cells.

  Journal of computational neuroscience 20020101

• Voltage-gated potassium ion channels in colon cancer.

  Oncology reports 20020101

• Ultrarapid delayed rectifier K(+) current in H9c2 rat ventricular cell line: biophysical property and molecular identity.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20020101

• Concentration- and time-dependent effect of aminooxyacetic acid on cortical epileptogenicity.

  Acta biologica Hungarica 20020101

• Differential expression of K+ currents in mammalian retinal bipolar cells.

  Visual neuroscience 20020101

• The Kv2.2 alpha subunit contributes to delayed rectifier K(+) currents in myocytes from rabbit corpus cavernosum.

  Journal of andrology 20020101

• Quinine suppresses extracellular potassium transients and ictal epileptiform activity without decreasing neuronal excitability in vitro.

  Neuroscience 20020101

• Involvement of electrical coupling in the in vivo ictal epileptiform activity induced by 4-aminopyridine in the neocortex.

  Neuroscience 20020101

• Calcitonin gene-related peptide dilates the pregnant rat uterine vascular bed via guanylate cyclase, ATP- and Ca-sensitive potassium channels and gap junctions.

  Current medical research and opinion 20020101

• Synergism between prostanoids and other vasoactive agents.

  Journal of cardiac surgery 20020101

• On the mechanisms of post-rest adaptation in the isolated electrically driven left atria of rats.

  Journal of basic and clinical physiology and pharmacology 20020101

• Aminopyridines for symptomatic treatment in multiple sclerosis.

  The Cochrane database of systematic reviews 20020101

• [Effect of synaptosomal cytosolic [3H]GABA pool depletion on secretory ability of alpha-latrotoxin].

  Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20020101

• Effects of potassium channel blockers on hyperinflation-induced rapidly adapting pulmonary stretch receptor stimulation in the rabbit.

  Life sciences 20011221

• Presynaptic Ca2+-activated K+ channels in glutamatergic hippocampal terminals and their role in spike repolarization and regulation of transmitter release.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20011215

• The role of Kv1.2-containing potassium channels in serotonin-induced glutamate release from thalamocortical terminals in rat frontal cortex.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20011215

• Control of Ca(2+) influx by cannabinoid and metabotropic glutamate receptors in rat cerebellar cortex requires K(+) channels.

  The Journal of physiology 20011215

• Testosterone-induced relaxation of rat aorta is androgen structure specific and involves K+ channel activation.

  Journal of applied physiology (Bethesda, Md. : 1985) 20011201

• Synaptic regulation of the slow Ca2+-activated K+ current in hippocampal CA1 pyramidal neurons: implication in epileptogenesis.

  Journal of neurophysiology 20011201

• Functional and molecular analysis of transient voltage-dependent K+ currents in rat hippocampal granule cells.

  The Journal of physiology 20011201

• Intrinsic optical signals and electrographic seizures in the rat limbic system.

  Neurobiology of disease 20011201

• Olfactory receptor axons influence the development of glial potassium currents in the antennal lobe of the moth Manduca sexta.

  Glia 20011201

• Histamine H3 receptor activation inhibits glutamate release from rat striatal synaptosomes.

  Neuropharmacology 20011201

• Mechanisms of axonal dysfunction after spinal cord injury: with an emphasis on the role of voltage-gated potassium channels.

  Brain research. Brain research reviews 20011201

• 4-aminopyridine poisoning of crows in the Chicago area.

  Veterinary and human toxicology 20011201

• Nitrergic relaxation in urethral smooth muscle: involvement of potassium channels and alternative redox forms of NO.

  Naunyn-Schmiedeberg's archives of pharmacology 20011201

• MaxiK channel-mediated relaxation of guinea-pig aorta following stimulation of IP receptor with beraprost via cyclic AMP-dependent and -independent mechanisms.

  Naunyn-Schmiedeberg's archives of pharmacology 20011201

• Tetra-butyl ammonium attenuates evoked release of acetylcholine from mouse hemidiaphragm preparation.

  Brain research bulletin 20011201

• Fatigue in progressive multiple sclerosis: results of a randomized, double-blind, placebo-controlled, crossover trial of oral 4-aminopyridine.

  Multiple sclerosis (Houndmills, Basingstoke, England) 20011201

• Poisoning with calcium channel blockers--a case report and review of the literature.

  Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 20011201

• Molecular composition of 4-aminopyridine-sensitive voltage-gated K(+) channels of vascular smooth muscle.

  Circulation research 20011123

• Heteromultimeric Kv1.2-Kv1.5 channels underlie 4-aminopyridine-sensitive delayed rectifier K(+) current of rabbit vascular myocytes.

  Circulation research 20011123

• Characterization of action potential-evoked calcium transients in mouse postganglionic sympathetic axon bundles.

  The Journal of physiology 20011115

• Basolateral K+ conductance establishes driving force for cation absorption by outer sulcus epithelial cells.

  The Journal of membrane biology 20011115

• Role of potassium channels in the relaxation induced by the nitric oxide (NO) donor DEA/NO in the isolated rat basilar artery.

  Neuroscience letters 20011102

• Inhibitory effect of bepridil on hKv1.5 channel current: comparison with amiodarone and E-4031.

  European journal of pharmacology 20011102

• GDNF acutely modulates excitability and A-type K(+) channels in midbrain dopaminergic neurons.

  Nature neuroscience 20011101

• Inhibition of voltage-gated K(+) currents by endothelin-1 in human pulmonary arterial myocytes.

  American journal of physiology. Lung cellular and molecular physiology 20011101

• Propafenone modulates potassium channel activities of vascular smooth muscle from rat portal veins.

  The Journal of pharmacology and experimental therapeutics 20011101

• Anorexic effect of K+ channel blockade in mesenteric arterial smooth muscle and intestinal epithelial cells.

  Journal of applied physiology (Bethesda, Md. : 1985) 20011101

• Initial and sustained phases of myogenic response of rat mesenteric small arteries.

  American journal of physiology. Heart and circulatory physiology 20011101

• Anandamide-induced relaxation of sheep coronary arteries: the role of the vascular endothelium, arachidonic acid metabolites and potassium channels.

  British journal of pharmacology 20011101

• Cellular target of voltage and calcium-dependent K(+) channel blockers involved in EDHF-mediated responses in rat superior mesenteric artery.

  British journal of pharmacology 20011101

• The contribution of ionic currents to changes in refractoriness of human atrial myocytes associated with chronic atrial fibrillation.

  Cardiovascular research 20011101

• Potassium channel blocker activates extracellular signal-regulated kinases through Pyk2 and epidermal growth factor receptor in rat cardiomyocytes.

  Journal of the American College of Cardiology 20011101

• Slowly inactivating potassium conductance (I(D)): a potential target for stroke therapy.

  Stroke 20011101

• Prolonged bursts occur in normal calcium in hippocampal slices after raising excitability and blocking synaptic transmission.

  Journal of neurophysiology 20011101

• Effects of different types of K+ channel modulators on the spontaneous myogenic contraction of guinea-pig urinary bladder smooth muscle.

  Acta physiologica Scandinavica 20011101

• Modulation of gonadotropin II release by K+ channel blockers in goldfish gonadotropes: a novel stimulatory action of 4-aminopyridine.

  Journal of neuroendocrinology 20011101

• Effects of 4-aminopyridine on electrically evoked cochlear emissions and mechano-transduction in guinea pig outer hair cells.

  Hearing research 20011101

• Opposing changes in phosphorylation of specific sites in synapsin I during Ca2+-dependent glutamate release in isolated nerve terminals.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20011015

• Sequential and opposite regulation of two outward K(+) currents by ET-1 in cultured striatal astrocytes.

  American journal of physiology. Cell physiology 20011001

• Calcium channel types involved in intrinsic amino acid neurotransmitters release evoked by depolarizing agents in cortical neurons.

  Neurochemistry international 20011001

• Augmented K(+) currents and mitochondrial membrane depolarization in pulmonary artery myocyte apoptosis.

  American journal of physiology. Lung cellular and molecular physiology 20011001

• Rapidly inactivating and non-inactivating calcium-activated potassium currents in frog saccular hair cells.

  The Journal of physiology 20011001

• Effects of potassium channel and Na+-Ca2+ exchange blockers on the responses of slowly adapting pulmonary stretch receptors to hyperinflation in flecainide-treated rats.

  British journal of pharmacology 20011001

• Brain-derived neurotrophic factor triggers a rapid glutamate release through increase of intracellular Ca(2+) and Na(+) in cultured cerebellar neurons.

  Journal of neuroscience research 20011001

• Voltage-gated sodium channels shape subthreshold EPSPs in layer 5 pyramidal neurons from rat prefrontal cortex.

  Journal of neurophysiology 20011001

• Role of potassium channels in isoflurane- and sevoflurane-induced attenuation of hypoxic pulmonary vasoconstriction in isolated perfused rabbit lungs.

  Anesthesiology 20011001

• Stability of 4-DMAP in solution.

  Drug development and industrial pharmacy 20011001

• Electrophysiological alterations and upregulation of ATP receptors in retinal glial Müller cells from rats infected with the Borna disease virus.

  Glia 20010901

• Characterization of mice with a combined suppression of I(to) and I(K,slow).

  American journal of physiology. Heart and circulatory physiology 20010901

• Modulation of excitability by alpha-dendrotoxin-sensitive potassium channels in neocortical pyramidal neurons.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20010901

• Hippocampal heterotopia lack functional Kv4.2 potassium channels in the methylazoxymethanol model of cortical malformations and epilepsy.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20010901

• Effects of the ion-channel blocker quinine on human sperm volume, kinematics and mucus penetration, and the involvement of potassium channels.

  Molecular human reproduction 20010901

• Decrease in the Ca2+-activated K+ current of pulmonary arterial smooth muscle in pulmonary hypertension rats.

  Naunyn-Schmiedeberg's archives of pharmacology 20010901

• Involvement of cyclic GMP and potassium channels in relaxation evoked by the nitric oxide donor, diethylamine NONOate, in the rat small isolated mesenteric artery.

  Naunyn-Schmiedeberg's archives of pharmacology 20010901

• Characterisation of [(125)I]-apamin binding sites in rat brain membranes with HE293 cells transfected with SK channel subtypes.

  Neuropharmacology 20010901

• Suppression of K(+)-induced hyperpolarization by phenylephrine in rat mesenteric artery: relevance to studies of endothelium-derived hyperpolarizing factor.

  British journal of pharmacology 20010901

• Dibutyryl-cyclic GMP induces peripheral antinociception via activation of ATP-sensitive K(+) channels in the rat PGE2-induced hyperalgesic paw.

  British journal of pharmacology 20010901

• Inhibitory effects of brefeldin A, a membrane transport blocker, on the bradykinin-induced hyperpolarization-mediated relaxation in the porcine coronary artery.

  British journal of pharmacology 20010901

• Compartmental models of rat cerebellar Purkinje cells based on simultaneous somatic and dendritic patch-clamp recordings.

  The Journal of physiology 20010901

• Effects of hydrogen peroxide on the transient outward current in rabbit atrial myocytes.

  Clinical and experimental pharmacology & physiology 20010901

• The role of endothelium-derived hyperpolarizing factor in the regulation of the uterine circulation in pregnant rats.

  American journal of obstetrics and gynecology 20010901

• Basic electrical properties of in situ endothelial cells of small pulmonary arteries during postnatal development.

  American journal of respiratory cell and molecular biology 20010901

• Adenosine inhibits glutamate exocytosis largely without interfering with Ca2+ influx in rat cerebrocortical synaptosomes.

  Neuroscience letters 20010831

• Taking the gender gap to heart.

  Circulation research 20010831

• Gender-based differences in cardiac repolarization in mouse ventricle.

  Circulation research 20010831

• Neurophysiological evidence of spared upper motor conduction fibers in clinically complete spinal cord injury: discomplete SCI in rats.

  Journal of the neurological sciences 20010815

• The relaxation induced by S-nitroso-glutathione and S-nitroso-N-acetylcysteine in rat aorta is not related to nitric oxide production.

  The Journal of pharmacology and experimental therapeutics 20010801

• Fenfluramine-induced pulmonary vasoconstriction: role of serotonin receptors and potassium channels.

  Journal of applied physiology (Bethesda, Md. : 1985) 20010801

• A model for 4-aminopyridine action on K channels: similarities to tetraethylammonium ion action.

  Biophysical journal 20010801

• Resolving the gating charge movement associated with late transitions in K channel activation.

  Biophysical journal 20010801

• General rules for the packing of hydrogen-bonded crystals as derived from the analysis of squaric acid anions: aminoaromatic nitrogen base co-crystals.

  Acta crystallographica. Section B, Structural science 20010801

• Impairment of hypoxic pulmonary vasoconstriction in mice lacking the voltage-gated potassium channel Kv1.5.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010801

• Expression and function of native potassium channel [K(V)alpha1] subunits in terminal arterioles of rabbit.

  The Journal of physiology 20010801

• Hypoxic vasoconstriction of rat main pulmonary artery: role of endogenous nitric oxide, potassium channels, and phosphodiesterase inhibition.

  Journal of cardiovascular pharmacology 20010801

• Nitric oxide activates voltage-dependent potassium currents of crustacean skeletal muscle.

  Nitric oxide : biology and chemistry 20010801

• 5-HT1A receptor-mediated activation of G-protein-gated inwardly rectifying K+ current in rat periaqueductal gray neurons.

  Neuropharmacology 20010801

• Membrane properties of principal neurons of the lateral superior olive.

  Journal of neurophysiology 20010801

• Effects of 4-aminopyridine on motor evoked potentials in patients with spinal cord injury: a double-blinded, placebo-controlled crossover trial.

  Journal of neurotrauma 20010801

• Highly 4-aminopyridine sensitive delayed rectifier current modulates the excitability of guinea pig cerebellar Purkinje cells.

  Experimental brain research 20010801

• Randomized trial of 4-aminopyridine in patients with chronic incomplete spinal cord injury.

  Journal of neurology 20010801

• [Quantitative evaluation of the effect of 3,4-diaminopyridine in a patient with Lambert-Eaton myasthenic syndrome using dynamic dynamometry].

  Rinsho shinkeigaku = Clinical neurology 20010801

• A novel mechanical dissociation technique for studying acutely isolated maturing Drosophila central neurons.

  Journal of neuroscience methods 20010730

• Lamotrigine inhibition of glutamate release from isolated cerebrocortical nerve terminals (synaptosomes) by suppression of voltage-activated calcium channel activity.

  Neuroreport 20010720

• High glucose impairs voltage-gated K(+) channel current in rat small coronary arteries.

  Circulation research 20010720

• Gap junctions synchronize the firing of inhibitory interneurons in guinea pig hippocampus.

  Brain research 20010713

• Bcl-2 decreases voltage-gated K+ channel activity and enhances survival in vascular smooth muscle cells.

  American journal of physiology. Cell physiology 20010701

• Relaxation to authentic nitric oxide and SIN-1 in rat isolated mesenteric arteries: variable role for smooth muscle hyperpolarization.

  British journal of pharmacology 20010701

• Long-term recordings of networks of immortalized GnRH neurons reveal episodic patterns of electrical activity.

  Journal of neurophysiology 20010701

• KT3.2 and KT3.3, two novel human two-pore K(+) channels closely related to TASK-1.

  Journal of neurophysiology 20010701

• Imaging of 4-AP-induced, GABA(A)-dependent spontaneous synchronized activity mediated by the hippocampal interneuron network.

  Journal of neurophysiology 20010701

• Pharmacological evidence for the activation of potassium channels as the mechanism involved in the hypotensive and vasorelaxant effect of dioclein in rat small resistance arteries.

  British journal of pharmacology 20010701

• Diversity of K+ channels in circular smooth muscle of opossum lower esophageal sphincter.

  Canadian journal of physiology and pharmacology 20010701

• Lipid peroxidation and aluminium effects on the cholinergic system in nerve terminals.

  Neurotoxicity research 20010701

• Developmental characteristics of epileptiform activity in immature rat neocortex: a comparison of four in vitro seizure models.

  Brain research. Developmental brain research 20010629

• 'Use-dependent' effects of cisapride on postrest action potentials in rabbit ventricular myocardium.

  European journal of pharmacology 20010622

• Theoretical analysis of the molecular determinants responsible for the K(+) channel blocking by aminopyridines.

  Biophysical chemistry 20010615

• Potassium channel blocker TEA prevents CA1 hippocampal injury following transient forebrain ischemia in adult rats.

  Neuroscience letters 20010608

• Potassium channels regulate tone in rat pulmonary veins.

  American journal of physiology. Lung cellular and molecular physiology 20010601

• Synchronized Ca2+ signals mediated by Ca2+ action potentials in the hippocampal neuron network in vitro.

  Cell calcium 20010601

• Superfusion of synaptosomes to study presynaptic mechanisms involved in neurotransmitter release from rat brain.

  Brain research. Brain research protocols 20010601

• Alterations in a redox oxygen sensing mechanism in chronic hypoxia.

  Journal of applied physiology (Bethesda, Md. : 1985) 20010601

• Membrane resonance and subthreshold membrane oscillations in mesencephalic V neurons: participants in burst generation.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20010601

• Dopamine D4 receptor-deficient mice display cortical hyperexcitability.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20010601

• Skin surface electric potential induced by ion-flux through epidermal cell layers.

  Biochemical and biophysical research communications 20010601

• Tonotopic map of potassium currents in chick auditory hair cells using an intact basilar papilla.

  Hearing research 20010601

• Pharmacological modulation of SK3 channels.

  Neuropharmacology 20010601

• Functional and molecular expression of a voltage-dependent K(+) channel (Kv1.1) in interstitial cells of Cajal.

  The Journal of physiology 20010601

• Mechanisms underlying presynaptic facilitatory effect of cyclothiazide at the calyx of Held of juvenile rats.

  The Journal of physiology 20010601

• Focal cooling rapidly terminates experimental neocortical seizures.

  Annals of neurology 20010601

• Normal coordinate analysis of 4-aminopyridine. Effect of substituent on pyridine ring in metal complexes of 4-substituted pyridines.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20010601

• Role of K+ -channels in homotaurine-induced analgesia.

  Fundamental & clinical pharmacology 20010601

• A voltage-dependent transient K(+) current in rat dental pulp cells.

  The Japanese journal of physiology 20010601

• The reversal of xylazine hydrochloride by yohimbine and 4-aminopyridine in goats.

  Journal of the South African Veterinary Association 20010601

• Effect of exogenous nitric oxide on electrogenesis in myelinated and unmyelinated nerve fibers.

  Bulletin of experimental biology and medicine 20010601

• Increment of calcium-activated and delayed rectifier potassium current by hyposmotic swelling in gastric antral circular myocytes of guinea pig.

  Acta pharmacologica Sinica 20010601

• minK-related peptide 1 associates with Kv4.2 and modulates its gating function: potential role as beta subunit of cardiac transient outward channel?

  Circulation research 20010525

• Inhibition of glutamate release by BIA 2-093 and BIA 2-024, two novel derivatives of carbamazepine, due to blockade of sodium but not calcium channels.

  Biochemical pharmacology 20010515

• Oxygen dilation in fetal pulmonary arterioles: role of K(+) channels.

  The Journal of surgical research 20010515

• Stretch-dependent potassium channels in murine colonic smooth muscle cells.

  The Journal of physiology 20010515

• Targeted replacement of KV1.5 in the mouse leads to loss of the 4-aminopyridine-sensitive component of I(K,slow) and resistance to drug-induced qt prolongation.

  Circulation research 20010511

• Ion channels associated with the ectopic discharges generated after segmental spinal nerve injury in the rat.

  Brain research 20010504

• Sites and ionic mechanisms of hypoxic vasoconstriction in frog skin.

  American journal of physiology. Regulatory, integrative and comparative physiology 20010501

• Mobilization of calcium from intracellular stores, potentiation of neurotransmitter-induced calcium transients, and capacitative calcium entry by 4-aminopyridine.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20010501

• A redox-based mechanism for the contractile and relaxing effects of NO in the guinea-pig gall bladder.

  The Journal of physiology 20010501

• Time-dependent distribution and neuronal localization of c-fos protein in the rat hippocampus following 4-aminopyridine seizures.

  Epilepsy research 20010501

• Capsaicin-induced relaxation in rabbit coronary artery.

  The Journal of veterinary medical science 20010501

• A comparison of methods for pharmacophore generation with the catalyst software and their use for 3D-QSAR: application to a set of 4-aminopyridine thrombin inhibitors.

  Mini reviews in medicinal chemistry 20010501

• Firing properties of identified superior laryngeal neurons in the nucleus ambiguus in the rat.

  Neuroscience letters 20010427

• Presynaptic N-methyl-D-aspartate receptor activation inhibits neurotransmitter release through nitric oxide formation in rat hippocampal nerve terminals.

  Brain research. Molecular brain research 20010418

• Distinct K currents result in physiologically distinct cell types in the inferior colliculus of the rat.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20010415

• Calcium influx-independent depression of transmitter release by 5-HT at lamprey spinal cord synapses.

  The Journal of physiology 20010415

• Acute exposure to trichloroethylene differentially alters the susceptibility to chemoconvulsants in mice.

  Toxicology 20010412

• Syntheses of the first amine-dicarboxyboranes and their bis(methylester) and bis(N-ethylamide) derivatives.

  Inorganic chemistry 20010409

• Effects of phosphodiesterase inhibitors on hypoxic pulmonary vasoconstriction. Influence of K(+) channels and nitric oxide.

  European journal of pharmacology 20010406

• Okadaic acid and cyclosporin A modulate [(3)H]GABA release from rat brain synaptosomes.

  Neurochemistry international 20010401

• Inhibition of vesicular glutamate storage and exocytotic release by Rose Bengal.

  Journal of neurochemistry 20010401

• Calcium dynamics and electrophysiological properties of cerebellar Purkinje cells in SCA1 transgenic mice.

  Journal of neurophysiology 20010401

• Differential expression of KV and KCa channels in vascular smooth muscle cells during 1-day culture.

  Pflugers Archiv : European journal of physiology 20010401

• The expression and regulation of depolarization-activated K+ channels in the insulin-secreting cell line INS-1.

  Pflugers Archiv : European journal of physiology 20010401

• [Effects of 4-aminopyridine on calcium currents and sodium currents in guinea pig ventricular myocytes].

  Yao xue xue bao = Acta pharmaceutica Sinica 20010401

• [Effect of 4-aminopyridine on taurine-regulated release of amino acid from rat cortical synaptosomes].

  Yao xue xue bao = Acta pharmaceutica Sinica 20010401

• Effects of pituitary adenylate cyclase activating polypeptide on lumbosacral preganglionic neurons in the neonatal rat spinal cord.

  Brain research 20010323

• Influence of admixed carboxymethylcellulose on release of 4-aminopyridine from hydroxypropyl methylcellulose matrix tablets.

  International journal of pharmaceutics 20010323

• Modulation of voltage-dependent K+ channel current in vascular smooth muscle cells from rat mesenteric arteries.

  The Journal of membrane biology 20010315

• Role of K+ channels in N-acetylprocainamide-induced relaxation of bovine tracheal smooth muscle.

  European journal of pharmacology 20010309

• Transient outward current modulates discontinuous conduction in rabbit ventricular cell pairs.

  Cardiovascular research 20010301

• Positive and negative contractile effects of somatostatin-14 on rat ventricular cardiomyocytes.

  Journal of cardiovascular pharmacology 20010301

• Three types of depolarization-activated potassium currents in acutely isolated mouse vestibular neurons.

  Journal of neurophysiology 20010301

• Synaptic and nonsynaptic contributions to giant ipsps and ectopic spikes induced by 4-aminopyridine in the hippocampus in vitro.

  Journal of neurophysiology 20010301

• HNS-32, a novel azulene-1-carboxamidine derivative, inhibits nifedipine-sensitive and -insensitive contraction of the isolated rabbit aorta.

  Naunyn-Schmiedeberg's archives of pharmacology 20010301

• Anticonvulsant properties and bio-guided isolation of palmitone from leaves of Annona diversifolia.

  Planta medica 20010301

• The effects of different 4-aminopyridine and morphine combinations on the intensity of morphine abstinence.

  Pharmacological research 20010301

• Coordinated control of cell Ca(2+) loading and triggered release from the sarcoplasmic reticulum underlies the rapid inotropic response to increased L-type Ca(2+) current.

  Circulation research 20010202

• Theta-frequency bursting and resonance in cerebellar granule cells: experimental evidence and modeling of a slow k+-dependent mechanism.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20010201

• Blockage of one class of potassium channel alters the effectiveness of halothane in a brain circuit of Drosophila.

  Anesthesia and analgesia 20010201

• Facilitated glutamatergic transmission in the striatum of D2 dopamine receptor-deficient mice.

  Journal of neurophysiology 20010201

• Swim stress alters the behavioural response of mice to GABA-related and some GABA-unrelated convulsants.

  Epilepsy research 20010201

• Modulation of diaphragm action potentials by K(+) channel blockers.

  Respiration physiology 20010201

• Pharmacological properties of excitation-contraction mechanisms in isolated mouse left atria.

  Pharmacology 20010201

• H3 receptor-mediated inhibition of intestinal acetylcholine release: pharmacological characterization of signal transduction pathways.

  Naunyn-Schmiedeberg's archives of pharmacology 20010201

• Distinguishing cochlear pathophysiology in 4-aminopyridine and furosemide treated ears using a nonlinear systems identification technique.

  The Journal of the Acoustical Society of America 20010201

• Validation of a CE assay for the analysis of isomeric aminopyridines and diaminopyridines.

  Journal of pharmaceutical and biomedical analysis 20010201

• Nitrooxy alkyl apovincaminate activates K+ currents in rat neocortical neurons.

  Japanese journal of pharmacology 20010201

• Large-conductance calcium-activated potassium channels in neonatal rat intracardiac ganglion neurons.

  Pflugers Archiv : European journal of physiology 20010201

• Chloride distribution in the CA1 region of newborn and adult hippocampus by light microscopic histochemistry.

  Histochemistry and cell biology 20010201

• The identification of the sympathetic neurons innervating the hamster submandibular gland and their electrophysiological membrane properties.

  The Bulletin of Tokyo Dental College 20010201

• Recording of spared motor evoked potentials and its augmentation by 4-aminopyridine in chronic spinal cord-injured rats.

  Chinese medical journal 20010201

• Cold transduction by inhibition of a background potassium conductance in rat primary sensory neurones.

  Neuroscience letters 20010119

• K(ATP) channel blockers selectively interact with A(1)-adenosine receptor mediated modulation of acetylcholine release in the rat hippocampus.

  Brain research 20010119

• Neurogenic bladder in Lambert-Eaton myasthenic syndrome and its response to 3,4-diaminopyridine.

  Journal of the neurological sciences 20010115

• Development and validation of a capillary electrophoresis assay for the determination of 3,4-diaminopyridine and 4-aminopyridine including related substances.

  Journal of chromatography. A 20010112

• Persistence of botulinum neurotoxin A demonstrated by sequential administration of serotypes A and E in rat EDL muscle.

  Toxicon : official journal of the International Society on Toxinology 20010101

• Dendritic coincidence detection of EPSPs and action potentials.

  Nature neuroscience 20010101

• Role of potassium channels in regulation of brain arteriolar tone: comparison of cerebrum versus brain stem.

  Stroke 20010101

• Localization and mechanisms of action of cannabinoid receptors at the glutamatergic synapses of the mouse nucleus accumbens.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20010101

• Modulation of Ca(2+) signaling by K(+) channels in a hypothalamic neuronal cell line (GT1-1).

  Journal of neurophysiology 20010101

• Phorbol ester-induced inhibition of potassium currents in rat sensory neurons requires voltage-dependent entry of calcium.

  Journal of neurophysiology 20010101

• Direct depolarization and antidromic action potentials transiently suppress dendritic IPSPs in hippocampal CA1 pyramidal cells.

  Journal of neurophysiology 20010101

• Two kinds of transient outward currents, I(A) and I(Adepol), in F76 and D1 soma membranes of the subesophageal ganglia of Helix aspersa.

  The Journal of membrane biology 20010101

• Activation of potassium conductance by ophiopogonin-D in acutely dissociated rat paratracheal neurones.

  British journal of pharmacology 20010101

• Three types of K(+) currents in murine osteocyte-like cells (MLO-Y4).

  Bone 20010101

• Mechanisms of NO-resistant relaxation induced by acetylcholine in rabbit renal arteries.

  The Journal of veterinary medical science 20010101

• Treatment of the neuromuscular junction with 4-aminopyridine results in improved reinnervation following nerve injury in neonatal rats.

  Neuroscience 20010101

• The effect of acidosis on the ECG of the rat heart.

  Experimental physiology 20010101

• BTS 72664-- a novel CNS drug with potential anticonvulsant, neuroprotective, and antimigraine properties.

  CNS drug reviews 20010101

• Is the proliferation of human chondrocytes regulated by ionic channels?

  Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 20010101

• A simple electrolyte for determination of small cations in natural waters by capillary electrophoresis.

  Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering 20010101

• Do interictal discharges promote or control seizures? Experimental evidence from an in vitro model of epileptiform discharge.

  Epilepsia 20010101

• GABA-mediated synchronization in the human neocortex: elevations in extracellular potassium and presynaptic mechanisms.

  Neuroscience 20010101

• Increased extracellular concentration of transmitter amino acids following 4-aminopyridine treatment in rat striatum.

  Neurobiology (Budapest, Hungary) 20010101

• Striatal catecholamine release induced by 4-aminopyridine.

  Neurobiology (Budapest, Hungary) 20010101

• Properties of interneurones in the intermediolateral cell column of the rat spinal cord: role of the potassium channel subunit Kv3.1.

  Neuroscience 20010101

• Mechanical and electrophysiological effects of thiopental on rat cardiac left ventricular papillary muscle.

  British journal of anaesthesia 20010101

• Acute spinal cord injury, part II: contemporary pharmacotherapy.

  Clinical neuropharmacology 20010101

• Pharmacology of airway afferent nerve activity.

  Respiratory research 20010101

• Aminopyridines for symptomatic treatment in multiple sclerosis.

  The Cochrane database of systematic reviews 20010101

• Nociceptin-induced outward current in substantia gelatinosa neurones of the adult rat spinal cord.

  Neuroscience 20010101

• Auxotonic contractile responses of rat tracheal and bronchial airway smooth muscle.

  Pulmonary pharmacology & therapeutics 20010101

• Evidence for a new mechanism of action of diclofenac: activation of K+ channels.

  Proceedings of the Western Pharmacology Society 20010101

• Voltage-clamp analysis of membrane currents and excitation-contraction coupling in a crustacean muscle.

  Journal of muscle research and cell motility 20010101

• Effect of ondansetron on the contractile responses to positive inotropic agents in electrically driven left atria of rats.

  Journal of basic and clinical physiology and pharmacology 20010101

• Antagonism of botulinum toxin A-mediated muscle paralysis by 3, 4-diaminopyridine delivered via osmotic minipumps.

  Toxicon : official journal of the International Society on Toxinology 20001001

• KCNA10: a novel ion channel functionally related to both voltage-gated potassium and CNG cation channels.

  American journal of physiology. Renal physiology 20000601

• TASK (TWIK-related acid-sensitive K+ channel) is expressed in glomerulosa cells of rat adrenal cortex and inhibited by angiotensin II.

  Molecular endocrinology (Baltimore, Md.) 20000601

• Gene structures and expression profiles of three human KCND (Kv4) potassium channels mediating A-type currents I(TO) and I(SA).

  Genomics 20000301

• The effects of quinine and 4-aminopyridine on conditioned place preference and changes in motor activity induced by morphine in rats.

  Progress in neuro-psychopharmacology & biological psychiatry 19990501

• Role of potassium channels in halothane-epinephrine arrhythmias.

  Research communications in molecular pathology and pharmacology 19980601

• Molecular identification of a component of delayed rectifier current in gastrointestinal smooth muscles.

  The American journal of physiology 19980501

• A novel inward rectifier K+ channel with unique pore properties.

  Neuron 19980501

• Genomic organization, chromosomal localization, tissue distribution, and biophysical characterization of a novel mammalian Shaker-related voltage-gated potassium channel, Kv1.7.

  The Journal of biological chemistry 19980306

• The effects of 4-aminopyridine and Bay K 8644 on verapamil-induced cardiovascular toxicity in anesthetized rats.

  Journal of toxicology. Clinical toxicology 19980101

• Signalling pathways in bradykinin- and nitric oxide-induced hypotension in the normotensive rat; role of K+-channels.

  British journal of pharmacology 19970701

• Effects of felbamate on muscarinic and metabotropic-glutamate agonist-mediated responses and magnesium-free or 4-aminopyridine-induced epileptiform activity in guinea pig olfactory cortex neurons in vitro.

  The Journal of pharmacology and experimental therapeutics 19960601

• Effect of calcium chloride and 4-aminopyridine therapy on desipramine toxicity in rats.

  Journal of toxicology. Clinical toxicology 19960101

• K-channel blockers attenuate the presynaptic effects of the D2/D3 agonist quinpirole in monkeys.

  Pharmacology, biochemistry, and behavior 19950801

• Felbamate displays in vitro antiepileptic effects as a broad spectrum excitatory amino acid receptor antagonist.

  European journal of pharmacology 19941227

• Novel zinc chelators which inhibit the binding of HIV-EP1 (HIV enhancer binding protein) to NF-kappa B recognition sequence.

  Journal of medicinal chemistry 19941209

• Interictal discharges in the hippocampus of rats with long-term pilocarpine seizures.

  Neuroscience letters 19940620

• Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.

  Molecular pharmacology 19940601

• Gating-dependent mechanism of 4-aminopyridine block in two related potassium channels.

  The Journal of general physiology 19931101

• Identity of a novel delayed rectifier current from human heart with a cloned K+ channel current.

  Circulation research 19930701

• Cloning of ShIII (Shaw-like) cDNAs encoding a novel high-voltage-activating, TEA-sensitive, type-A K+ channel.

  Proceedings. Biological sciences 19920422

• Effects of anticonvulsant drugs on 4-aminopyridine-induced seizures in mice.

  Epilepsy research 19920301

• Molecular basis of functional diversity of voltage-gated potassium channels in mammalian brain.

  The EMBO journal 19891101

• Sprouting of mammalian motor neurones at nodes of Ranvier: the role of the denervated motor endplate.

  Brain research 19830404

• 4-Aminopyridine reversal of fentanyl-induced respiratory depression in normocapnic and hypercapnic patients.

  British journal of anaesthesia 19810401