506-32-1 | Arachidonic acid

Packsize	Purity	Availability	Price	Discounted Price
1g	10%	in stock	$27.00	$19.00
5g	10%	in stock	$79.00	$55.00
25g	10%	in stock	$236.00	$165.00

Description

• Catalog Number: AB45569
• Chemical Name: Arachidonic acid
• CAS Number: 506-32-1
• Molecular Formula: C20H32O2
• Molecular Weight: 304.4669
• MDL Number: MFCD00004417
• SMILES: CCCCCC=CCC=CCC=CCC=CCCCC(=O)O

Computed Properties

• Complexity: 362
• Covalently-Bonded Unit Count: 1
• Defined Bond Stereocenter Count: 4
• Heavy Atom Count: 22
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 14
• XLogP3: 6.3

Literature

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  Chemico-biological interactions 20180201

• Insights into myalgic encephalomyelitis/chronic fatigue syndrome phenotypes through comprehensive metabolomics.

  Scientific reports 20180101

• Liqustri lucidi Fructus inhibits hepatic injury and functions as an antioxidant by activation of AMP-activated protein kinase in vivo and in vitro.

  Chemico-biological interactions 20170125

• Anti-inflammatory and antiedematogenic activity of the Ocimum basilicum essential oil and its main compound estragole: In vivo mouse models.

  Chemico-biological interactions 20160925

• Inhibition of interleukin-1β-induced endothelial tissue factor expression by the synthetic cannabinoid WIN 55,212-2.

  Oncotarget 20160920

• Discovery of Novel 15-Lipoxygenase Activators To Shift the Human Arachidonic Acid Metabolic Network toward Inflammation Resolution.

  Journal of medicinal chemistry 20160512

• Effects of Common Pesticides on Prostaglandin D2 (PGD2) Inhibition in SC5 Mouse Sertoli Cells, Evidence of Binding at the COX-2 Active Site, and Implications for Endocrine Disruption.

  Environmental health perspectives 20160401

• 5-, 12- and 15-Hydroxyeicosatetraenoic acids induce cellular hypertrophy in the human ventricular cardiomyocyte, RL-14 cell line, through MAPK- and NF-κB-dependent mechanism.

  Archives of toxicology 20160201

• Change in soluble epoxide hydrolase (sEH) during cisplatin-induced acute renal failure in mice.

  The Journal of toxicological sciences 20150801

• The peroxidase activity of ADM-Fe(3+) cooperates with lipid peroxidation: The participation of hydroperoxide and hydroxyl radicals in the damage to proteins and DNA.

  Chemico-biological interactions 20150705

• 15-Oxoeicosatetraenoic acid is a 15-hydroxyprostaglandin dehydrogenase-derived electrophilic mediator of inflammatory signaling pathways.

  Chemico-biological interactions 20150605

• Targeting of splice variants of human cytochrome P450 2C8 (CYP2C8) to mitochondria and their role in arachidonic acid metabolism and respiratory dysfunction.

  The Journal of biological chemistry 20141024

• Tandem pore domain halothane-inhibited K+ channel subunits THIK1 and THIK2 assemble and form active channels.

  The Journal of biological chemistry 20141010

• Acute arsenic treatment alters arachidonic acid and its associated metabolite levels in the brain of C57Bl/6 mice.

  Canadian journal of physiology and pharmacology 20140801

• Lipidomic analyses of female mice lacking hepatic lipase and endothelial lipase indicate selective modulation of plasma lipid species.

  Lipids 20140601

• Acute mercury toxicity modulates cytochrome P450, soluble epoxide hydrolase and their associated arachidonic acid metabolites in C57Bl/6 mouse heart.

  Toxicology letters 20140407

• Arachidonic acid affects biofilm formation and PGE2 level in Candida albicans and non-albicans species in presence of subinhibitory concentration of fluconazole and terbinafine.

  The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases 20140101

• JAK2-targeted anti-inflammatory effect of a resveratrol derivative 2,4-dihydroxy-N-(4-hydroxyphenyl)benzamide.

  Biochemical pharmacology 20131215

• Investigations on the metabolic stability of cytosolic phospholipase A2α inhibitors with 1-indolylpropan-2-one structure.

  Chemico-biological interactions 20131125

• Effects of cannabinoids and related fatty acids upon the viability of P19 embryonal carcinoma cells.

  Archives of toxicology 20131101

• Isoliquiritigenin induces growth inhibition and apoptosis through downregulating arachidonic acid metabolic network and the deactivation of PI3K/Akt in human breast cancer.

  Toxicology and applied pharmacology 20131001

• Effect of human 15-lipoxygenase-1 metabolites on vascular function in mouse mesenteric arteries and hearts.

  Prostaglandins & other lipid mediators 20131001

• Protective effect of conjugated linolenic acid isomers present in vegetable oils against arsenite-induced renal toxicity in rat model.

  Nutrition (Burbank, Los Angeles County, Calif.) 20130601

• Ammodytoxins efficiently release arachidonic acid and induce apoptosis in a motoneuronal cell line in an enzymatic activity-dependent manner.

  Neurotoxicology 20130301

• 2-Arachidonoyl-glycerol- and arachidonic acid-stimulated neutrophils release antimicrobial effectors against E. coli, S. aureus, HSV-1, and RSV.

  Journal of leukocyte biology 20130201

• Inhibition of platelet-mediated arterial thrombosis and platelet granule exocytosis by 3',4'-dihydroxyflavonol and quercetin.

  Platelets 20130101

• Contrary effects of sphingosine-1-phosphate on expression of α-smooth muscle actin in transforming growth factor β1-stimulated lung fibroblasts.

  European journal of pharmacology 20121205

• The diacylglycerol lipases: structure, regulation and roles in and beyond endocannabinoid signalling.

  Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20121205

• Modulation of neuropathic-pain-related behaviour by the spinal endocannabinoid/endovanilloid system.

  Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20121205

• Acute arsenic toxicity alters cytochrome P450 and soluble epoxide hydrolase and their associated arachidonic acid metabolism in C57Bl/6 mouse heart.

  Xenobiotica; the fate of foreign compounds in biological systems 20121201

• Kupffer cell depletion attenuates leptin-mediated methoxamine-stimulated portal perfusion pressure and thromboxane A2 release in a rodent model of NASH-cirrhosis.

  Clinical science (London, England : 1979) 20121201

• In vitro platelet antiaggregatory properties of 4-methylcoumarins.

  Biochimie 20121201

• Arachidonic acid induces an increase of β-1,4-galactosyltransferase I expression in MDA-MB-231 breast cancer cells.

  Journal of cellular biochemistry 20121101

• Relation between dietary fat intake type and serum fatty acid status in children with cystic fibrosis.

  Journal of pediatric gastroenterology and nutrition 20121101

• Phospholipid sources for adrenic acid mobilization in RAW 264.7 macrophages. Comparison with arachidonic acid.

  Biochimica et biophysica acta 20121101

• Improved β-carotene biosynthesis and gene transcription in Blakeslea trispora with arachidonic acid.

  Biotechnology letters 20121101

• The effects of polyphenols on oxidative stress and the arachidonic acid cascade. Implications for the prevention/treatment of high prevalence diseases.

  Biochemical pharmacology 20121101

• New approaches to assess the transthyretin binding capacity of bioactivated thyroid hormone disruptors.

  Toxicological sciences : an official journal of the Society of Toxicology 20121101

• Chronic doxorubicin cardiotoxicity modulates cardiac cytochrome P450-mediated arachidonic acid metabolism in rats.

  Drug metabolism and disposition: the biological fate of chemicals 20121101

• Simultaneous activation of p38 and JNK by arachidonic acid stimulates the cytosolic phospholipase A2-dependent synthesis of lipid droplets in human monocytes.

  Journal of lipid research 20121101

• EV-077 in vitro inhibits platelet aggregation in type-2 diabetics on aspirin.

  Thrombosis research 20121101

• High-density lipoprotein and 4F peptide reduce systemic inflammation by modulating intestinal oxidized lipid metabolism: novel hypotheses and review of literature.

  Arteriosclerosis, thrombosis, and vascular biology 20121101

• A cellular lipidomic study on the Aβ-induced neurotoxicity and neuroprotective effects of EGCG by using UPLC/MS-based glycerolipids profiling and multivariate analysis.

  Molecular bioSystems 20121030

• Regulation of the expression of key genes involved in HDL metabolism by unsaturated fatty acids.

  The British journal of nutrition 20121028

• Prostaglandin H synthase-2-catalyzed oxygenation of 2-arachidonoylglycerol is more sensitive to peroxide tone than oxygenation of arachidonic acid.

  The Journal of biological chemistry 20121026

• Glutathione promotes prostaglandin H synthase (cyclooxygenase)-dependent formation of malondialdehyde and 15(S)-8-iso-prostaglandin F2α.

  FEBS letters 20121019

• Metabolomic investigation of the anti-platelet aggregation activity of ginsenoside Rk₁ reveals attenuated 12-HETE production.

  Journal of proteome research 20121005

• Breastfeeding and long-chain polyunsaturated fatty acid intake in the first 4 post-natal months and infant cognitive development: an observational study.

  Maternal & child nutrition 20121001

• Dietary linoleic acid elevates endogenous 2-AG and anandamide and induces obesity.

  Obesity (Silver Spring, Md.) 20121001

• Arachidonic acid depletion extends survival of cold-stored platelets by interfering with the [glycoprotein Ibα--14-3-3ζ] association.

  Haematologica 20121001

• Interaction between NO and COX pathways modulating hepatic endothelial cells from control and cirrhotic rats.

  Journal of cellular and molecular medicine 20121001

• Stilbenoids from Gnetum macrostachyum attenuate human platelet aggregation and adhesion.

  Phytotherapy research : PTR 20121001

• Epithelium-dependent modulation of responsiveness of airways from caveolin-1 knockout mice is mediated through cyclooxygenase-2 and 5-lipoxygenase.

  British journal of pharmacology 20121001

• Influence of dietary fatty acids on muscle fatty acid composition and expression levels of Δ6 desaturase-like and Elovl5-like elongase in common carp (Cyprinus carpio var. Jian).

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20121001

• The in vitro effects of verbascoside on human platelet aggregation.

  Journal of thrombosis and thrombolysis 20121001

• Platelet aggregometry in the presence of PGE(1) provides a reliable method for cilostazol monitoring.

  Thrombosis research 20121001

• Anti-inflammatory mechanism of action of azithromycin in LPS-stimulated J774A.1 cells.

  Pharmacological research 20121001

• Arachidonic acid stimulates DNA synthesis in brown preadipocytes through the activation of protein kinase C and MAPK.

  Biochimica et biophysica acta 20121001

• Platelet mapping as part of modified thromboelastography (TEG®) in patients undergoing cardiac surgery and cardiopulmonary bypass.

  Anaesthesia 20121001

• Report: Platelet aggregation inhibition activity of selected legumes of Pakistan.

  Pakistan journal of pharmaceutical sciences 20121001

• Biological efficacy of twice daily aspirin in type 2 diabetic patients with coronary artery disease.

  American heart journal 20121001

• Modulation of plant TPC channels by polyunsaturated fatty acids.

  Journal of experimental botany 20121001

• The different inhibitory effects of Huang-Lian-Jie-Du-Tang on cyclooxygenase 2 and 5-lipoxygenase.

  Journal of ethnopharmacology 20120928

• Preparation of human milk fat substitutes from palm stearin with arachidonic and docosahexaenoic acid: combination of enzymatic and physical methods.

  Journal of agricultural and food chemistry 20120919

• Antiplatelet effect of phloroglucinol is related to inhibition of cyclooxygenase, reactive oxygen species, ERK/p38 signaling and thromboxane A2 production.

  Toxicology and applied pharmacology 20120915

• Identification of novel bioactive aldehyde-modified phosphatidylethanolamines formed by lipid peroxidation.

  Free radical biology & medicine 20120915

• Characterization of the in vivo antiplatelet activity of the antihypertensive agent losartan.

  Journal of cardiovascular pharmacology and therapeutics 20120901

• Teleost fish larvae adapt to dietary arachidonic acid supply through modulation of the expression of lipid metabolism and stress response genes.

  The British journal of nutrition 20120901

• Effects of fatty acids on endothelial cells: inflammation and monocyte adhesion.

  The Journal of surgical research 20120901

• trans Arachidonic acid isomers inhibit NADPH-oxidase activity by direct interaction with enzyme components.

  Biochimica et biophysica acta 20120901

• Chemical-physical changes in cell membrane microdomains of breast cancer cells after omega-3 PUFA incorporation.

  Cell biochemistry and biophysics 20120901

• A mechanism underlying the effects of polyunsaturated fatty acids on breast cancer.

  International journal of molecular medicine 20120901

• Differences between group X and group V secretory phospholipase A(2) in lipolytic modification of lipoproteins.

  Cellular & molecular biology letters 20120901

• Clinical outcomes using a platelet function-guided approach for secondary prevention in patients with ischemic stroke or transient ischemic attack.

  Stroke 20120901

• A novel C(28)-hydroxylated lupeolic acid suppresses the biosynthesis of eicosanoids through inhibition of cytosolic phospholipase A(2).

  Biochemical pharmacology 20120901

• Chronic lithium feeding reduces upregulated brain arachidonic acid metabolism in HIV-1 transgenic rat.

  Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 20120901

• The synthesis and in vivo pharmacokinetics of fluorinated arachidonic acid: implications for imaging neuroinflammation.

  Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20120901

• Multiple roles of heparin in the aggregation of p25α.

  Journal of molecular biology 20120824

• [Neurological, neuropsychological, and ophthalmological evolution after one year of docosahexaenoic acid supplementation in phenylketonuric patients].

  Revista de neurologia 20120816

• Lamotrigine blocks NMDA receptor-initiated arachidonic acid signalling in rat brain: implications for its efficacy in bipolar disorder.

  The international journal of neuropsychopharmacology 20120801

• Hind limb suspension and long-chain omega-3 PUFA increase mRNA endocannabinoid system levels in skeletal muscle.

  The Journal of nutritional biochemistry 20120801

• Hypertension, cardiovascular risk and polymorphisms in genes controlling the cytochrome P450 pathway of arachidonic acid: A sex-specific relation?

  Prostaglandins & other lipid mediators 20120801

• Role of the adenosine(2A) receptor-epoxyeicosatrienoic acid pathway in the development of salt-sensitive hypertension.

  Prostaglandins & other lipid mediators 20120801

• Effects of chronic clozapine administration on markers of arachidonic acid cascade and synaptic integrity in rat brain.

  Psychopharmacology 20120801

• Possible mechanisms underlying the biphasic regulatory effects of arachidonic acid on Ca2+ signaling in HEK293 cells.

  Cellular signalling 20120801

• Conversion of human 5-lipoxygenase to a 15-lipoxygenase by a point mutation to mimic phosphorylation at Serine-663.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20120801

• The P2Y2/Src/p38/COX-2 pathway is involved in the resistance to ursolic acid-induced apoptosis in colorectal and prostate cancer cells.

  Biochimie 20120801

• OX1 orexin/hypocretin receptor signaling through arachidonic acid and endocannabinoid release.

  Molecular pharmacology 20120801

• Aspirin response variability after major orthopedic surgery.

  Thrombosis research 20120801

• Arachidonate-enriched triglyceride oil does not promote tumor development in a rat medium-term multi-organ carcinogenesis model.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120801

• Antitumor and immunostimulatory activity of a polysaccharide-protein complex from Scolopendra subspinipes mutilans L. Koch in tumor-bearing mice.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120801

• Capacitative and non-capacitative signaling complexes in human platelets.

  Biochimica et biophysica acta 20120801

• Simplified platelet sample preparation for SDS-PAGE-based proteomic studies.

  Proteomics. Clinical applications 20120801

• Influence of cigarette smoking on synthesis of eicosanoids, isoprostanes and lipoxygenase metabolites in apical periodontitis.

  Archives of oral biology 20120801

• Irbesartan does not influence the antiplatelet effect of aspirin in spontaneously hypertensive rats.

  CNS neuroscience & therapeutics 20120801

• Status of cis and trans fatty acids in Brazilian adolescent mothers and their newborns.

  Journal of pediatric and adolescent gynecology 20120801

• Gabapentin's minimal action on markers of rat brain arachidonic acid metabolism agrees with its inefficacy against bipolar disorder.

  Prostaglandins, leukotrienes, and essential fatty acids 20120801

• Regulation of leukotriene B4 secretion by human corneal, conjunctival, and meibomian gland epithelial cells.

  Archives of ophthalmology (Chicago, Ill. : 1960) 20120801

• Arachidonic acid stimulates TNFα production in Kupffer cells via a reactive oxygen species-pERK1/2-Egr1-dependent mechanism.

  American journal of physiology. Gastrointestinal and liver physiology 20120715

• A unique alkaline pH-regulated and fatty acid-activated tandem pore domain potassium channel (K₂P) from a marine sponge.

  The Journal of experimental biology 20120715

• Investigating substrate promiscuity in cyclooxygenase-2: the role of Arg-120 and residues lining the hydrophobic groove.

  The Journal of biological chemistry 20120713

• Production of prostaglandin E₂ in response to infection with modified vaccinia Ankara virus.

  Virology 20120705

• Inhibition of soluble epoxide hydrolase reduces food intake and increases metabolic rate in obese mice.

  Nutrition, metabolism, and cardiovascular diseases : NMCD 20120701

• Association between Ω3 and Ω6 fatty acid intakes and serum inflammatory markers in COPD.

  The Journal of nutritional biochemistry 20120701

• Arachidonic acid metabolism via cytosolic phospholipase A2 α induces cytotoxicity in niemann-pick disease type C cells.

  Journal of cellular physiology 20120701

• Docosahexaenoic acid and arachidonic acid prevent essential fatty acid deficiency and hepatic steatosis.

  JPEN. Journal of parenteral and enteral nutrition 20120701

• Long-chain PUFA in granulocytes, mononuclear cells, and RBC in patients with cystic fibrosis: relation to liver disease.

  Journal of pediatric gastroenterology and nutrition 20120701

• The histamine autoreceptor is a short isoform of the H₃ receptor.

  British journal of pharmacology 20120701

• Targeted proteomics of the eicosanoid biosynthetic pathway completes an integrated genomics-proteomics-metabolomics picture of cellular metabolism.

  Molecular & cellular proteomics : MCP 20120701

• Knocking out the dopamine reuptake transporter (DAT) does not change the baseline brain arachidonic acid signal in the mouse.

  The International journal of neuroscience 20120701

• Concomitant activation of functionally opposing prostacyclin and thromboxane prostanoid receptors by cyclo-oxygenase-1-mediated prostacyclin synthesis in mouse arteries.

  Experimental physiology 20120701

• Novel surfactants with diglutamic acid polar head group: drug solubilization and toxicity studies.

  Pharmaceutical research 20120701

• Fyn inhibition by cycloalkane-fused 1,2-dithiole-3-thiones enhances antioxidant capacity and protects mitochondria from oxidative injury.

  Molecular pharmacology 20120701

• Inhibition of soluble epoxide hydrolase limits niacin-induced vasodilation in mice.

  Journal of cardiovascular pharmacology 20120701

• Role of intramitochondrial arachidonic acid and acyl-CoA synthetase 4 in angiotensin II-regulated aldosterone synthesis in NCI-H295R adrenocortical cell line.

  Endocrinology 20120701

• Differential regulation of neurotoxin in HIV clades: role of cocaine and methamphetamine.

  Current HIV research 20120701

• Arachidonic acid/docosahexaenoic acid-supplemented diet in early life reduces body weight gain, plasma lipids, and adiposity in later life in ApoE*3Leiden mice.

  Molecular nutrition & food research 20120701

• Determination of arachidonic acid by on-line solid-phase extraction HPLC with UV detection for screening of cytosolic phospholipase A2α inhibitors.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120701

• Platelet-neutrophil aggregate formation in blood samples from dogs with systemic inflammatory disorders.

  American journal of veterinary research 20120701

• Epigenetic modifications in frontal cortex from Alzheimer's disease and bipolar disorder patients.

  Translational psychiatry 20120701

• MAP-kinase regulated cytosolic phospholipase A2 activity is essential for production of infectious hepatitis C virus particles.

  PLoS pathogens 20120701

• Acetaminophen inhibits cytochrome c redox cycling induced lipid peroxidation.

  Biochemical and biophysical research communications 20120629

• Inhibition of transforming growth factor-β-activated kinase-1 blocks cancer cell adhesion, invasion, and metastasis.

  British journal of cancer 20120626

• [Assessment of airway inflammation in chronic obstructive pulmonary disease: biomarkers in exhaled breath condensate].

  Orvosi hetilap 20120603

• The investigation into indomethacin-induced potentiation of the contractile response to antigen in ovalbumin-sensitized guinea-pig tracheas.

  Fundamental & clinical pharmacology 20120601

• The anti-inflammatory activities of an extract and compounds isolated from Platycladus orientalis (Linnaeus) Franco in vitro and ex vivo.

  Journal of ethnopharmacology 20120601

• Lipid alterations in human colon epithelial cells induced to differentiation and/or apoptosis by butyrate and polyunsaturated fatty acids.

  The Journal of nutritional biochemistry 20120601

• The effects of arachidonic acid on the endocrine and osmoregulatory response of tilapia (Oreochromis mossambicus) acclimated to seawater and subjected to confinement stress.

  Fish physiology and biochemistry 20120601

• Improving arachidonic acid accumulation in Mortierella alpina through B-group vitamin addition.

  Bioprocess and biosystems engineering 20120601

• Ferritin couples iron and fatty acid metabolism.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20120601

• Effects of clothianidin exposure on sperm quality, testicular apoptosis and fatty acid composition in developing male rats.

  Cell biology and toxicology 20120601

• Exogenous arachidonate restores the dimethoate-induced inhibition of steroidogenesis in rat interstitial cells.

  Lipids 20120601

• Purification and characterization of the recombinant human prostaglandin H synthase-2 expressed in Pichia pastoris.

  Protein expression and purification 20120601

• Inhibitory effect of 5,8,11-eicosatrienoic acid on angiogenesis.

  Prostaglandins, leukotrienes, and essential fatty acids 20120601

• Examination of the carboxylesterase phenotype in human liver.

  Archives of biochemistry and biophysics 20120601

• STIM1 regulates calcium signaling in taste bud cells and preference for fat in mice.

  The Journal of clinical investigation 20120601

• Influence of marine n-3 polyunsaturated fatty acids on immune function and a systematic review of their effects on clinical outcomes in rheumatoid arthritis.

  The British journal of nutrition 20120601

• Paracetamol (acetaminophen), aspirin (acetylsalicylic acid) and indomethacin are anti-androgenic in the rat foetal testis.

  International journal of andrology 20120601

• Novel soluble epoxide hydrolase inhibitor protects mitochondrial function following stress.

  Canadian journal of physiology and pharmacology 20120601

• Production of leukotriene B4 by Paracoccidioides brasiliensis.

  Yeast (Chichester, England) 20120601

• Antiinflammatory, analgesic and antioxidant activities of Cyathula prostrata (Linn.) Blume (Amaranthaceae).

  Journal of ethnopharmacology 20120507

• Transgenic expression of an altered angiotensin type I AT1 receptor resulting in marked modulation of vascular type I collagen.

  Journal of cellular physiology 20120501

• Hypertonic saline inhibits arachidonic acid priming of the human neutrophil oxidase.

  The Journal of surgical research 20120501

• Protective effects of arachidonic acid against palmitic acid-mediated lipotoxicity in HIT-T15 cells.

  Molecular and cellular biochemistry 20120501

• Ethnicity, plasma phospholipid fatty acid composition and inflammatory/endothelial activation biomarkers in the Multi-Ethnic Study of Atherosclerosis (MESA).

  European journal of clinical nutrition 20120501

• Role of 15-lipoxygenase/15-hydroxyeicosatetraenoic acid in hypoxia-induced pulmonary hypertension.

  The journal of physiological sciences : JPS 20120501

• Arachidonic acid regulation of the cytosolic phospholipase A 2α/cyclooxygenase-2 pathway in mouse endometrial stromal cells.

  Fertility and sterility 20120501

• Long-chain fatty acids and inflammation.

  The Proceedings of the Nutrition Society 20120501

• Sepsis-associated changes of the arachidonic acid metabolism and their diagnostic potential in septic patients.

  Critical care medicine 20120501

• Science, sceptics, sepsis, and simplicity.

  Critical care medicine 20120501

• Effects of acepromazine maleate on platelet function assessed by use of adenosine diphosphate activated- and arachidonic acid- activated modified thromboelastography in healthy dogs.

  American journal of veterinary research 20120501

• Fish oil supplementation maintains adequate plasma arachidonate in cats, but similar amounts of vegetable oils lead to dietary arachidonate deficiency from nutrient dilution.

  Nutrition research (New York, N.Y.) 20120501

• Differential age- and disease-related effects on the expression of genes related to the arachidonic acid signaling pathway in schizophrenia.

  Psychiatry research 20120430

• Activation of mitochondrial calcium-independent phospholipase A2γ (iPLA2γ) by divalent cations mediating arachidonate release and production of downstream eicosanoids.

  The Journal of biological chemistry 20120427

• 20-Hydroxyeicosatetraenoic acid (20-HETE) is a novel activator of transient receptor potential vanilloid 1 (TRPV1) channel.

  The Journal of biological chemistry 20120420

• 11,12,20-Trihydroxy-eicosa-8(Z)-enoic acid: a selective inhibitor of 11,12-EET-induced relaxations of bovine coronary and rat mesenteric arteries.

  American journal of physiology. Heart and circulatory physiology 20120415

• Cysteinyl leukotrienes mediate the response of submucosal ganglia from rat colon to bradykinin.

  European journal of pharmacology 20120415

• A review of the possible role of the essential fatty acids and fish oils in the aetiology, prevention or pharmacotherapy of schizophrenia.

  Journal of clinical pharmacy and therapeutics 20120401

• Detrimental effects of arachidonic acid and its metabolites in cellular and mouse models of Alzheimer's disease: structural insight.

  Neurobiology of aging 20120401

• The utility of (11)C-arachidonate PET to study in vivo dopaminergic neurotransmission in humans.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20120401

• Cannabinoid CB1 receptor activation, pharmacological blockade, or genetic ablation affects the function of the muscarinic auto- and heteroreceptor.

  Naunyn-Schmiedeberg's archives of pharmacology 20120401

• The role of calcium-independent phospholipase A2γ in modulation of aqueous humor drainage and Ca2+ sensitization of trabecular meshwork contraction.

  American journal of physiology. Cell physiology 20120401

• Maintenance of arachidonic acid and evidence of Δ5 desaturation in cats fed γ-linolenic and linoleic acid enriched diets.

  Lipids 20120401

• Reversal of the anti-platelet effects of aspirin and clopidogrel.

  Journal of thrombosis and haemostasis : JTH 20120401

• Targeting soluble epoxide hydrolase for inflammation and pain - an overview of pharmacology and the inhibitors.

  Inflammation & allergy drug targets 20120401

• Addendum: Gamma-tocopherol, cox-2, and cancer risk.

  Medical hypotheses 20120401

• Interaction between head and neck squamous cell carcinoma cells and fibroblasts in the biosynthesis of PGE2.

  Journal of lipid research 20120401

• Persistent high on-treatment platelet reactivity in acute coronary syndrome.

  Journal of thrombosis and thrombolysis 20120401

• Effects of large doses of arachidonic acid added to docosahexaenoic acid on social impairment in individuals with autism spectrum disorders: a double-blind, placebo-controlled, randomized trial.

  Journal of clinical psychopharmacology 20120401

• Effects of dietary combination of n-3 and n-9 fatty acids on the deposition of linoleic and arachidonic acid in broiler chicken meats.

  Poultry science 20120401

• Fatty acid compositions of preterm and term colostrum, transitional and mature milks in a sub-Saharan population with high fish intakes.

  Prostaglandins, leukotrienes, and essential fatty acids 20120401

• Gestational age dependent changes of the fetal brain, liver and adipose tissue fatty acid compositions in a population with high fish intakes.

  Prostaglandins, leukotrienes, and essential fatty acids 20120401

• Dynamic eicosanoid responses upon different inhibitor and combination treatments on the arachidonic acid metabolic network.

  Molecular bioSystems 20120401

• Investigation on signal transduction pathways after H(1) receptor activated by histamine in C6 glioma cells: involvement of phosphatidylinositol and arachidonic acid metabolisms.

  Journal of the Chinese Medical Association : JCMA 20120401

• Nitric oxide, peroxynitrite, S-nitrosothiols and thiols are unlikely to exert their effects on recombinant cyclooxygenase-1 and cyclooxygenase-2 activity in vitro by modifying cysteine moieties.

  Nitric oxide : biology and chemistry 20120331

• A novel role of brain-type ACS4 isotype in neuronal differentiation.

  Biochemical and biophysical research communications 20120316

• Angiotensin II stimulates epithelial sodium channels in the cortical collecting duct of the rat kidney.

  American journal of physiology. Renal physiology 20120315

• Arachidonic acid and docosahexaenoic acid supplemented to an essential fatty acid-deficient diet alters the response to endotoxin in rats.

  Metabolism: clinical and experimental 20120301

• Effect of different levels of docosahexaenoic acid supply on fatty acid status and linoleic and α-linolenic acid conversion in preterm infants.

  Journal of pediatric gastroenterology and nutrition 20120301

• Growth, clinical chemistry and immune function in domestic piglets fed varying ratios of arachidonic acid and DHA.

  The British journal of nutrition 20120301

• 15-Hydroxyprostaglandin dehydrogenase associates with poor prognosis in breast cancer, induces epithelial-mesenchymal transition, and promotes cell migration in cultured breast cancer cells.

  The Journal of pathology 20120301

• ELOVL4 protein preferentially elongates 20:5n3 to very long chain PUFAs over 20:4n6 and 22:6n3.

  Journal of lipid research 20120301

• D-4F-mediated reduction in metabolites of arachidonic and linoleic acids in the small intestine is associated with decreased inflammation in low-density lipoprotein receptor-null mice.

  Journal of lipid research 20120301

• 2,3,7,8-Tetrachlorodibenzo-p-dioxin treatment alters eicosanoid levels in several organs of the mouse in an aryl hydrocarbon receptor-dependent fashion.

  Toxicology and applied pharmacology 20120301

• Efficacy and mechanism of action of arachidonic acid in the treatment of hamsters infected with Schistosoma mansoni or Schistosoma haematobium.

  International journal of antimicrobial agents 20120301

• Update on lipids and mitochondrial function: impact of dietary n-3 polyunsaturated fatty acids.

  Current opinion in clinical nutrition and metabolic care 20120301

• Polyunsaturated fatty acids confer cryoresistance on megakaryocytes generated from cord blood and also enhance megakaryocyte production from cryopreserved cord blood cells.

  Cytotherapy 20120301

• Gene expression differences in skin fibroblasts in identical twins discordant for type 1 diabetes.

  Diabetes 20120301

• Intracellular free calcium content plays a role in low magnesium-induced increases in prostacyclin production.

  Magnesium research 20120301

• Axonal neuropathy-associated TRPV4 regulates neurotrophic factor-derived axonal growth.

  The Journal of biological chemistry 20120217

• Group VIA PLA2 (iPLA2β) is activated upstream of p38 mitogen-activated protein kinase (MAPK) in pancreatic islet β-cell signaling.

  The Journal of biological chemistry 20120217

• Axonal gradient of arachidonic acid-containing phosphatidylcholine and its dependence on actin dynamics.

  The Journal of biological chemistry 20120217

• Identification of a Δ6 fatty acid elongase gene for arachidonic acid biosynthesis localized to the endoplasmic reticulum in the green microalga Myrmecia incisa Reisigl.

  Gene 20120210

• Imaging brain signal transduction and metabolism via arachidonic and docosahexaenoic acid in animals and humans.

  Brain research bulletin 20120210

• Therapeutic effect of Yunnan Baiyao on rheumatoid arthritis was partially due to regulating arachidonic acid metabolism in osteoblasts.

  Journal of pharmaceutical and biomedical analysis 20120205

• Proteomic analysis of colon tissue from interleukin-10 gene-deficient mice fed polyunsaturated Fatty acids with comparison to transcriptomic analysis.

  Journal of proteome research 20120203

• Transgenic production of arachidonic acid in oilseeds.

  Transgenic research 20120201

• Inhibitory effects of secoiridoids from the roots of Gentiana straminea on stimulus-induced superoxide generation, phosphorylation and translocation of cytosolic compounds to plasma membrane in human neutrophils.

  Phytotherapy research : PTR 20120201

• Integration of transient receptor potential canonical channels with lipids.

  Acta physiologica (Oxford, England) 20120201

• The shunting of arachidonic acid metabolism to 5-lipoxygenase and cytochrome p450 epoxygenase antagonizes the anti-cancer effect of cyclooxygenase-2 inhibition in head and neck cancer cells.

  Cellular oncology (Dordrecht) 20120201

• Differences in arachidonic acid levels and fatty acid desaturase (FADS) gene variants in African Americans and European Americans with diabetes or the metabolic syndrome.

  The British journal of nutrition 20120201

• Significant inverse associations of serum n-6 fatty acids with plasma plasminogen activator inhibitor-1.

  The British journal of nutrition 20120201

• Inhibition of 5-lipoxygenase by U73122 is due to covalent binding to cysteine 416.

  Biochimica et biophysica acta 20120201

• Dynamics of arachidonic acid mobilization by inflammatory cells.

  Biochimica et biophysica acta 20120201

• Cyp2c44 epoxygenase is essential for preventing the renal sodium absorption during increasing dietary potassium intake.

  Hypertension (Dallas, Tex. : 1979) 20120201

• Arachidonic acid mobilizes Ca2+ from the endoplasmic reticulum and an acidic store in rat pancreatic β cells.

  Cell calcium 20120201

• Fatty acids and vitamins generate singlet oxygen under UVB irradiation.

  Experimental dermatology 20120201

• Inhibition of neuroblastoma cell proliferation with omega-3 fatty acids and treatment of a murine model of human neuroblastoma using a diet enriched with omega-3 fatty acids in combination with sunitinib.

  Pediatric research 20120201

• Fatty acid, cholesterol and fat-soluble vitamin composition of wild and captive freshwater crayfish (Astacus leptodactylus).

  Food science and technology international = Ciencia y tecnologia de los alimentos internacional 20120201

• 5-Lipoxygenase metabolic contributions to NSAID-induced organ toxicity.

  Advances in therapy 20120201

• Hsp70 alters tau function and aggregation in an isoform specific manner.

  Biochemistry 20120131

• Effects of diet and behavioral enrichment on free fatty acids in the aged canine brain.

  Neuroscience 20120127

• A target analogue imprinted polymer for the recognition of antiplatelet active ingredients in Radix Salviae Miltiorrhizae by LC/MS/MS.

  Journal of pharmaceutical and biomedical analysis 20120125

• Identification of 3,N(4)-etheno-5-methyl-2'-deoxycytidine in human DNA: a new modified nucleoside which may perturb genome methylation.

  Chemical research in toxicology 20120113

• TRPV4 mediates tumor-derived endothelial cell migration via arachidonic acid-activated actin remodeling.

  Oncogene 20120112

• mtDNA T8993G mutation-induced mitochondrial complex V inhibition augments cardiolipin-dependent alterations in mitochondrial dynamics during oxidative, Ca(2+), and lipid insults in NARP cybrids: a potential therapeutic target for melatonin.

  Journal of pineal research 20120101

• Platelet aggregation is dependent on platelet count in patients with coronary artery disease.

  Thrombosis research 20120101

• Identification and functional characterization of zebrafish K(2P)10.1 (TREK2) two-pore-domain K(+) channels.

  Biochimica et biophysica acta 20120101

• Twice daily aspirin to improve biological aspirin efficacy in patients with essential thrombocythemia.

  Thrombosis research 20120101

• Maternal supplementation with dietary arachidonic and docosahexaenoic acids during lactation elevates bone mass in weanling rat and guinea pig offspring even if born small sized.

  Prostaglandins, leukotrienes, and essential fatty acids 20120101

• Embryo and larva development in Dentex dentex, a marine pelagophil teleost: an endeavor to find a series of new fatty acid interrelations.

  Journal of experimental zoology. Part A, Ecological genetics and physiology 20120101

• Enhanced prostaglandin F2α formation in human pregnancy and the effect of increased oily fish intake: results from the Salmon in Pregnancy Study.

  Prostaglandins, leukotrienes, and essential fatty acids 20120101

• Anti-inflammatory effects of benfotiamine are mediated through the regulation of the arachidonic acid pathway in macrophages.

  Free radical biology & medicine 20120101

• Tissue-specific LCPUFA accretion in fetal humans.

  Prostaglandins, leukotrienes, and essential fatty acids 20120101

• Gestational age dependent content, composition and intrauterine accretion rates of fatty acids in fetal white adipose tissue.

  Prostaglandins, leukotrienes, and essential fatty acids 20120101

• Fetal intrauterine whole body linoleic, arachidonic and docosahexaenoic acid contents and accretion rates.

  Prostaglandins, leukotrienes, and essential fatty acids 20120101

• Production of prostaglandins, isoprostanes and thromboxane by Aspergillus fumigatus: identification by gas chromatography-tandem mass spectrometry and quantification by enzyme immunoassay.

  Molecular immunology 20120101

• Expression of arachidonate metabolism enzymes and receptors in nasal polyps of aspirin-hypersensitive asthmatics.

  International archives of allergy and immunology 20120101

• Platelet reactivity in type 2 diabetes mellitus: a comparative analysis with survivors of myocardial infarction and the role of glycaemic control.

  Platelets 20120101

• Arachidonic acid inhibits Na⁺-K⁺-ATPase via cytochrome P-450, lipoxygenase and protein kinase C-dependent pathways in sheep pulmonary artery.

  Vascular pharmacology 20120101

• Ratio of serum n-3 to n-6 polyunsaturated fatty acids and the incidence of major adverse cardiac events in patients undergoing percutaneous coronary intervention.

  Circulation journal : official journal of the Japanese Circulation Society 20120101

• Triplatin, a platelet aggregation inhibitor from the salivary gland of the triatomine vector of Chagas disease, binds to TXA(2) but does not interact with glycoprotein PVI.

  Thrombosis and haemostasis 20120101

• Endothelial nitric oxide and 15-lipoxygenase-1 metabolites independently mediate relaxation of the rabbit aorta.

  Vascular pharmacology 20120101

• Conversion of mouse fibroblasts to sphere cells induced by AlbuMAXI-containing medium.

  Frontiers in bioscience (Elite edition) 20120101

• Ca2+ signaling and exocytosis in pituitary corticotropes.

  Cell calcium 20120101

• Secretory phospholipase A2 group IID Is involved in progesterone-induced acrosomal exocytosis of human spermatozoa.

  Journal of andrology 20120101

• Total dietary fat and fatty acid content modifies plasma phospholipid fatty acids, desaturase activity indices, and urinary prostaglandin E in women.

  Nutrition research (New York, N.Y.) 20120101

• Restriction of meat, fish, and poultry in omnivores improves mood: a pilot randomized controlled trial.

  Nutrition journal 20120101

• Caffeic acid phenethyl ester and its amide analogue are potent inhibitors of leukotriene biosynthesis in human polymorphonuclear leukocytes.

  PloS one 20120101

• iPLA2β overexpression in smooth muscle exacerbates angiotensin II-induced hypertension and vascular remodeling.

  PloS one 20120101

• Noncanonical Hedgehog signaling.

  Vitamins and hormones 20120101

• Improved mitochondrial function with diet-induced increase in either docosahexaenoic acid or arachidonic acid in membrane phospholipids.

  PloS one 20120101

• Regulation of chemokine and chemokine receptor expression by PPARγ in adipocytes and macrophages.

  PloS one 20120101

• Replacement of retinyl esters by polyunsaturated triacylglycerol species in lipid droplets of hepatic stellate cells during activation.

  PloS one 20120101

• Evaluation of the relationship between endometriosis and omega-3 and omega-6 polyunsaturated fatty acids.

  Iranian biomedical journal 20120101

• [Elicitor activity of chitosan and arachidonic acid: their similarity and distinction].

  Prikladnaia biokhimiia i mikrobiologiia 20120101

• Role of leukotrienes on protozoan and helminth infections.

  Mediators of inflammation 20120101

• [The changes of metabolism in myocardium at ischemia-reperfusion and activating of the ATP-sensitive potassium channels].

  Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20120101

• Dose-dependent changes in neuroinflammatory and arachidonic acid cascade markers with synaptic marker loss in rat lipopolysaccharide infusion model of neuroinflammation.

  BMC neuroscience 20120101

• [Erythrocyte lipid composition at different stages of type 1 diabetes in children].

  Biomeditsinskaia khimiia 20120101

• Brain anticonvulsant protection of mice given chronic carbamazepine under various fatty acid and magnesium diet conditions.

  Prostaglandins, leukotrienes, and essential fatty acids 20120101

• BF066, a novel dual target antiplatelet agent without significant bleeding.

  PloS one 20120101

• Platelet aggregation and anti-inflammatory effects of garden pea, Desi chickpea and Kabuli chickpea.

  Acta poloniae pharmaceutica 20120101

• Arachidonic acid enhances caffeine-induced cell death via caspase-independent cell death.

  Scientific reports 20120101

• Effects of diet and/or exercise in enhancing spinal cord sensorimotor learning.

  PloS one 20120101

• Antiplatelet therapy in peripheral artery disease.

  Handbook of experimental pharmacology 20120101

• Biosynthesis of eoxin C4 by porcine leukocytes.

  Prostaglandins, leukotrienes, and essential fatty acids 20120101

• Cytosolic phospholipase A2 alpha/arachidonic acid signaling mediates depolarization-induced suppression of excitation in the cerebellum.

  PloS one 20120101

• [Fatty acids intake and serum lipids profile in overweighted and obese adults].

  Roczniki Panstwowego Zakladu Higieny 20120101

• Arachidonic acid and its COX1/2 metabolites inhibit interferon-γ mediated induction of indoleamine-2,3 dioxygenase in THP-1 cells and human monocytes.

  Prostaglandins, leukotrienes, and essential fatty acids 20120101

• Arachidonic acid derivatives and their role in peripheral nerve degeneration and regeneration.

  TheScientificWorldJournal 20120101

• [Useful pharmacologic treatment in impaired social interaction in autism spectrum disorders].

  Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica 20120101

• Effects of Hsp90 inhibitors, geldanamycin and its analog, on ceramide metabolism and cytotoxicity in PC12 cells.

  The Journal of toxicological sciences 20120101

• 11-Oxoeicosatetraenoic acid is a cyclooxygenase-2/15-hydroxyprostaglandin dehydrogenase-derived antiproliferative eicosanoid.

  Chemical research in toxicology 20111219

• Uptake and utilization of arachidonic acid in infective larvae of Angiostrongylus cantonensis.

  Journal of helminthology 20111201

• Cortisol response to air exposure in Solea senegalensis post-larvae is affected by dietary arachidonic acid-to-eicosapentaenoic acid ratio.

  Fish physiology and biochemistry 20111201

• Identification of lipids that accumulate during the routine storage of prestorage leukoreduced red blood cells and cause acute lung injury.

  Transfusion 20111201

• Cytochrome P450 metabolites of arachidonic acid are elevated in stroke patients compared with healthy controls.

  Clinical science (London, England : 1979) 20111201

• Chemical composition of hepatic lipids mediates reperfusion injury of the macrosteatotic mouse liver through thromboxane A(2).

  Journal of hepatology 20111201

• Chronic valproate treatment blocks D2-like receptor-mediated brain signaling via arachidonic acid in rats.

  Neuropharmacology 20111201

• Comparison of venous and arterial blood sampling for the assessment of platelet aggregation with whole blood impedance aggregometry.

  Scandinavian journal of clinical and laboratory investigation 20111201

• Heart arachidonic acid is uniquely sensitive to dietary arachidonic acid and docosahexaenoic acid content in domestic piglets.

  Prostaglandins, leukotrienes, and essential fatty acids 20111201

• Identification of novel oxidized levuglandin D2 in marine red alga and mouse tissue.

  Journal of lipid research 20111201

• Supplementation of DHA-rich microalgal oil or fish oil during the suckling period in mildly n-3 fatty acid-deficient rat pups.

  Lipids 20111201

• Differences in preterm and term milk fatty acid compositions may be caused by the different hormonal milieu of early parturition.

  Prostaglandins, leukotrienes, and essential fatty acids 20111201

• Electrospray ionization tandem mass spectrometry of sodiated adducts of cholesteryl esters.

  Lipids 20111201

• Inhibitory effect of plant-originated glycoprotein (27 kDa) on expression of matrix metalloproteinase-9 in cadmium chloride-induced BNL CL.2 cells.

  Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 20111201

• Arachidonic acid- and prostaglandin E2-induced cerebral vasodilation is mediated by carbon monoxide, independent of reactive oxygen species in piglets.

  American journal of physiology. Heart and circulatory physiology 20111201

• Post term dietary-induced changes in DHA and AA status relate to gains in weight, length, and head circumference in preterm infants.

  Prostaglandins, leukotrienes, and essential fatty acids 20111201

• Anti-platelet effects of yuzu extract and its component.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20111201

• Effects of dynamic exercise on plasma arachidonic acid epoxides and diols in human volunteers.

  International journal of sport nutrition and exercise metabolism 20111201

• A phase I study to characterize the multiple-dose pharmacokinetics, pharmacodynamics and safety of new enteric-coated triflusal formulations in healthy male volunteers.

  Expert opinion on drug metabolism & toxicology 20111201

• Red blood cells, transfusion-related acute lung injury, and lipids: a role for liporeduction?

  Transfusion 20111201

• Prostaglandin E₂ production in mice is reduced by consumption of range-fed sources of red meat.

  Nutrition research (New York, N.Y.) 20111201

• Gap junctions contribute to astrocytic resistance against zinc toxicity.

  Brain research bulletin 20111125

• Effectiveness of Vernonia scorpioides ethanolic extract against skin inflammatory processes.

  Journal of ethnopharmacology 20111118

• Endocannabinoid hydrolysis generates brain prostaglandins that promote neuroinflammation.

  Science (New York, N.Y.) 20111111

• Pseudohyperphosphorylation has differential effects on polymerization and function of tau isoforms.

  Biochemistry 20111108

• Discovery of a protein-metabolite interaction between unsaturated fatty acids and the nuclear receptor Nur77 using a metabolomics approach.

  Journal of the American Chemical Society 20111102

• Dietary conjugated linoleic acid alters long chain polyunsaturated fatty acid metabolism in brain and liver of neonatal pigs.

  The Journal of nutritional biochemistry 20111101

• The skinny on tuna fat: health implications.

  Public health nutrition 20111101

• Lipid mediators in cerebral spinal fluid of traumatic brain injured patients.

  The Journal of trauma 20111101

• Intrauterine, postpartum and adult relationships between arachidonic acid (AA) and docosahexaenoic acid (DHA).

  Prostaglandins, leukotrienes, and essential fatty acids 20111101

• Decreased postnatal docosahexaenoic and arachidonic acid blood levels in premature infants are associated with neonatal morbidities.

  The Journal of pediatrics 20111101

• Antioxidant, antinociceptive, and anti-inflammatory properties of the ethanolic extract of Combretum duarteanum in rodents.

  Journal of medicinal food 20111101

• The role of 20-HETE in androgen-mediated hypertension.

  Prostaglandins & other lipid mediators 20111101

• Protocatechualdehyde synergizes with aspirin at the platelet cyclooxygenase-1 level.

  Planta medica 20111101

• Using a fingertip whole blood sample for rapid fatty acid measurement: method validation and correlation with erythrocyte polar lipid compositions in UK subjects.

  The British journal of nutrition 20111101

• Cytochrome P450 epoxygenase CYP2J2 attenuates nephropathy in streptozotocin-induced diabetic mice.

  Prostaglandins & other lipid mediators 20111101

• Additive effects of fatty acid mixtures on the levels and ratio of amyloid β40/42 peptides differ from the effects of individual fatty acids.

  Journal of neuroscience research 20111101

• Functional and bioinformatic characterisation of sequence variants of Fad3 gene from flax.

  Journal of the science of food and agriculture 20111101

• Inhibition of epoxy-eicosanoid degradation improves the tocolytic effects of indomethacin in the uterus from pregnant women.

  Prostaglandins & other lipid mediators 20111101

• Improved bioavailability of epoxyeicosatrienoic acids reduces TP-receptor agonist-induced tension in human bronchi.

  American journal of physiology. Lung cellular and molecular physiology 20111101

• LDL from obese patients with the metabolic syndrome show increased lipid peroxidation and activate platelets.

  Diabetologia 20111101

• Soluble epoxide hydrolase inhibition, epoxygenated fatty acids and nociception.

  Prostaglandins & other lipid mediators 20111101

• Inhibition of aldose reductase prevents endotoxin-induced inflammation by regulating the arachidonic acid pathway in murine macrophages.

  Free radical biology & medicine 20111101

• 11,12-EET increases porto-sinusoidal resistance and may play a role in endothelial dysfunction of portal hypertension.

  Prostaglandins & other lipid mediators 20111101

• Augmentation of chemotherapy-triggered glioma cell apoptosis by blockade of arachidonic acid metabolism--the potential role of ceramide accumulation.

  Medical hypotheses 20111101

• Regulation of inflammation in cancer by eicosanoids.

  Prostaglandins & other lipid mediators 20111101

• Orai channel-dependent activation of phospholipase C-δ: a novel mechanism for the effects of calcium entry on calcium oscillations.

  The Journal of physiology 20111101

• Ethanol promotes chemically induced oral cancer in mice through activation of the 5-lipoxygenase pathway of arachidonic acid metabolism.

  Cancer prevention research (Philadelphia, Pa.) 20111101

• Tyrosine phosphatase SHP2 regulates the expression of acyl-CoA synthetase ACSL4.

  Journal of lipid research 20111101

• CYP-eicosanoids--a new link between omega-3 fatty acids and cardiac disease?

  Prostaglandins & other lipid mediators 20111101

• Lipocalin Q83 reveals a dual ligand binding mode with potential implications for the functions of siderocalins.

  Biochemistry 20111101

• Dopamine receptors, motor responses, and dopaminergic agonists.

  The neurologist 20111101

• (R)-Profens are substrate-selective inhibitors of endocannabinoid oxygenation by COX-2.

  Nature chemical biology 20111101

• Analysis of two major intracellular phospholipases A(2) (PLA(2)) in mast cells reveals crucial contribution of cytosolic PLA(2)α, not Ca(2+)-independent PLA(2)β, to lipid mobilization in proximal mast cells and distal fibroblasts.

  The Journal of biological chemistry 20111028

• Stereocontrol of arachidonic acid oxygenation by vertebrate lipoxygenases: newly cloned zebrafish lipoxygenase 1 does not follow the Ala-versus-Gly concept.

  The Journal of biological chemistry 20111028

• Group X secreted phospholipase A2 proenzyme is matured by a furin-like proprotein convertase and releases arachidonic acid inside of human HEK293 cells.

  The Journal of biological chemistry 20111021

• Reversing nerve cell pathology by optimizing modulatory action on target ion channels.

  Biophysical journal 20111019

• P450-based porous silicon biosensor for arachidonic acid detection.

  Biosensors & bioelectronics 20111015

• Ginger phenylpropanoids inhibit IL-1beta and prostanoid secretion and disrupt arachidonate-phospholipid remodeling by targeting phospholipases A2.

  Journal of immunology (Baltimore, Md. : 1950) 20111015

• Altered arachidonate distribution in macrophages from caveolin-1 null mice leading to reduced eicosanoid synthesis.

  The Journal of biological chemistry 20111007

• Polymorphic human prostaglandin H synthase-2 proteins and their interactions with cyclooxygenase substrates and inhibitors.

  The pharmacogenomics journal 20111001

• IgE, COX-2, and IL-4 are expressed by DEHP through p38 MAPK and suppressed by plant glycoprotein (75 kDa) in ICR mice.

  Inflammation 20111001

• Phospholipase A(2) of peroxiredoxin 6 has a critical role in tumor necrosis factor-induced apoptosis.

  Cell death and differentiation 20111001

• Maternal intake of flaxseed-based diet (Linum usitatissimum) on hippocampus fatty acid profile: implications for growth, locomotor activity and spatial memory.

  Nutrition (Burbank, Los Angeles County, Calif.) 20111001

• Regulation of forskolin-induced cAMP production by cytochrome P450 epoxygenase metabolites of arachidonic acid in HEK293 cells.

  Cell biology and toxicology 20111001

• Activation by 2-arachidonoylglycerol of platelet p38MAPK/cPLA2 pathway.

  Journal of cellular biochemistry 20111001

• Point-of-care assessment of platelet aggregation in paediatric open heart surgery.

  British journal of anaesthesia 20111001

• Blockade of endocannabinoid hydrolytic enzymes attenuates precipitated opioid withdrawal symptoms in mice.

  The Journal of pharmacology and experimental therapeutics 20111001

• GVI phospholipase A2 role in the stimulatory effect of sphingosine-1-phosphate on TRPC5 cationic channels.

  Cell calcium 20111001

• Comparison of metabolites in exhaled breath and bronchoalveolar lavage fluid samples in a mouse model of asthma.

  Journal of applied physiology (Bethesda, Md. : 1985) 20111001

• Contact sensitizers modulate the arachidonic acid metabolism of PMA-differentiated U-937 monocytic cells activated by LPS.

  Toxicology and applied pharmacology 20111001

• LC/ESR/MS study of pH-dependent radical generation from 15-LOX-catalyzed DPA peroxidation.

  Free radical biology & medicine 20111001

• Chronic olanzapine treatment decreases arachidonic acid turnover and prostaglandin E₂ concentration in rat brain.

  Journal of neurochemistry 20111001

• Inhibition of renin release by arachidonic acid metabolites, 12(s)-HPETE and 12-HETE: role of TRPV1 channels.

  Endocrinology 20111001

• Dynamics of different arachidonic acid orientations bound to prostaglandin endoperoxide synthases.

  European journal of medicinal chemistry 20111001

• Synthesis and characterization of novel PUFA esters exhibiting potential anticancer activities: an in vitro study.

  European journal of medicinal chemistry 20111001

• Unexpected depletion of plasma arachidonate and total protein in cats fed a low arachidonic acid diet due to peroxidation.

  The British journal of nutrition 20111001

• [Cyclooxygenase inhibitors in some dietary vegetables inhibit platelet aggregation function induced by arachidonic acid].

  Zhongguo shi yan xue ye xue za zhi 20111001

• [Aspirin response and related factors in aged patients].

  Zhonghua xin xue guan bing za zhi 20111001

• Associations between arachidonic acid metabolism gene polymorphisms and prostate cancer risk.

  The Prostate 20110915

• Lymphatic absorption of choline plasmalogen is much higher than that of ethanolamine plasmalogen in rats.

  European journal of nutrition 20110901

• Infection, inflammation, and bone regeneration: a paradoxical relationship.

  Journal of dental research 20110901

• Perinodal adipose tissue and mesenteric lymph node activation during reactivated TNBS-colitis in rats.

  Digestive diseases and sciences 20110901

• Allosteric modulation of the M₃ muscarinic receptor by amiodarone and N-ethylamiodarone: application of the four-ligand allosteric two-state model.

  Molecular pharmacology 20110901

• Arachidonic acid products in airway nociceptor activation during acute lung injury.

  Experimental physiology 20110901

• The influence of dietary supplementation of arachidonic acid on prostaglandin production and oxidative stress in the Pacific oyster Crassostrea gigas.

  Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20110901

• Terminal fatty-acyl-CoA desaturase involved in sex pheromone biosynthesis in the winter moth (Operophtera brumata).

  Insect biochemistry and molecular biology 20110901

• Improved functional vasodilation in obese Zucker rats following exercise training.

  American journal of physiology. Heart and circulatory physiology 20110901

• Effects of cytochrome P-450 metabolites of arachidonic acid on the epithelial sodium channel (ENaC).

  American journal of physiology. Renal physiology 20110901

• Evaluation of bioequivalency and toxicological effects of three sources of arachidonic acid (ARA) in domestic piglets.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110901

• Docosahexaenoic acid stimulates tube formation in first trimester trophoblast cells, HTR8/SVneo.

  Placenta 20110901

• Regulation of CRIg expression and phagocytosis in human macrophages by arachidonate, dexamethasone, and cytokines.

  The American journal of pathology 20110901

• Potential interaction of natural dietary bioactive compounds with COX-2.

  Journal of molecular graphics & modelling 20110901

• The antiplatelet activity of camel urine.

  Journal of alternative and complementary medicine (New York, N.Y.) 20110901

• Substrate binding to mammalian 15-lipoxygenase.

  Journal of computer-aided molecular design 20110901

• Siderocalin Q83 exhibits differential slow dynamics upon ligand binding.

  Journal of biomolecular NMR 20110901

• Cell biology of H2O2 generation in the thyroid: investigation of the control of dual oxidases (DUOX) activity in intact ex vivo thyroid tissue and cell lines.

  Molecular and cellular endocrinology 20110822

• Arachidonic acid modulates Na+ currents by non-metabolic and metabolic pathways in rat cerebellar granule cells.

  The Biochemical journal 20110815

• A profile of NSAID-targeted arachidonic acid metabolisms in human embryonic stem cells (hESCs): implication of the negative effects of NSAIDs on heart tissue regeneration.

  International journal of cardiology 20110804

• Dietary docosahexaenoic acid in combination with arachidonic acid ameliorates allergen-induced dermatitis in mice.

  Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 20110801

• Dietary fatty acid composition influences tissue lipid profiles and regulation of body temperature in Japanese quail.

  Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20110801

• Fermentation characteristics of Mortierella alpina in response to different nitrogen sources.

  Applied biochemistry and biotechnology 20110801

• Docosahexaenoic acid modulates in vitro the inflammation of celiac disease in intestinal epithelial cells via the inhibition of cPLA2.

  Clinical nutrition (Edinburgh, Scotland) 20110801

• Profiling of fatty acids released during calcium-induced mitochondrial permeability transition in isolated rabbit kidney cortex mitochondria.

  Toxicology in vitro : an international journal published in association with BIBRA 20110801

• Regulation of stearoyl-coenzyme A desaturase and fatty acid delta-6 desaturase-2 expression by linoleic acid and arachidonic acid in human sebocytes leads to enhancement of proinflammatory activity but does not affect lipogenesis.

  The British journal of dermatology 20110801

• MALDI imaging MS of phospholipids in the mouse lung.

  Journal of lipid research 20110801

• Aspirin failure in patients presenting with acute cerebrovascular ischaemia.

  Thrombosis and haemostasis 20110801

• Odd-chain polyunsaturated fatty acids in thraustochytrids.

  Phytochemistry 20110801

• Acute doxorubicin toxicity differentially alters cytochrome P450 expression and arachidonic acid metabolism in rat kidney and liver.

  Drug metabolism and disposition: the biological fate of chemicals 20110801

• Selective PGE(2) suppression inhibits colon carcinogenesis and modifies local mucosal immunity.

  Cancer prevention research (Philadelphia, Pa.) 20110801

• Integrative investigation of lipidome and signal pathways in human endothelial cells under oxidative stress.

  Molecular bioSystems 20110801

• Role of cytosolic phospholipase A(2)α in cell rounding and cytotoxicity induced by ceramide-1-phosphate via ceramide kinase.

  Archives of biochemistry and biophysics 20110801

• Identification of a cyclooxygenase gene from the red alga Gracilaria vermiculophylla and bioconversion of arachidonic acid to PGF(2α) in engineered Escherichia coli.

  Applied microbiology and biotechnology 20110801

• The role of the central arachidonic acid-thromboxane A2 cascade in cardiovascular regulation during hemorrhagic shock in rats.

  Prostaglandins, leukotrienes, and essential fatty acids 20110801

• Overexpression of Arabidopsis ACBP3 enhances NPR1-dependent plant resistance to Pseudomonas syringe pv tomato DC3000.

  Plant physiology 20110801

• 15-Deoxy-Δ(12,14)-prostaglandin J(2) interferes inducible synthesis of prostaglandins E(2) and F(2α) that suppress subsequent adipogenesis program in cultured preadipocytes.

  Prostaglandins & other lipid mediators 20110801

• The relationship between platelet reactivity and infarct-related artery patency in patients presenting with a ST-elevation myocardial infarction.

  Thrombosis and haemostasis 20110801

• Supplemental arachidonic acid-enriched oil improves the taste of thigh meat of Hinai-jidori chickens.

  Poultry science 20110801

• The effects of an oral supplement enriched with fish oil, prebiotics, and antioxidants on nutrition status in Crohn's disease patients.

  Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition 20110801

• Altered neuroinflammatory, arachidonic acid cascade and synaptic markers in postmortem Alzheimer's disease brain.

  Translational psychiatry 20110801

• Bioactive lipoxygenase metabolites stimulation of NADPH oxidases and reactive oxygen species.

  Molecules and cells 20110731

• Absorption of the novel artemisinin derivatives artemisone and artemiside: potential application of Pheroid™ technology.

  International journal of pharmaceutics 20110729

• Protective effects of dipeptidyl peptidase-4 (DPP-4) inhibitor against increased β cell apoptosis induced by dietary sucrose and linoleic acid in mice with diabetes.

  The Journal of biological chemistry 20110722

• The roles of CYP450 epoxygenases and metabolites, epoxyeicosatrienoic acids, in cardiovascular and malignant diseases.

  Advanced drug delivery reviews 20110718

• Antinociceptive and antiinflammatory activities of Adiantum latifolium Lam.: evidence for a role of IL-1β inhibition.

  Journal of ethnopharmacology 20110714

• Inclusion of flaxseed in hay- and barley silage diets increases alpha-linolenic acid in cow plasma independent of forage type.

  Lipids 20110701

• Effects of parenteral soybean oil lipid emulsion on the long-chain polyunsaturated fatty acid profile in very-low-birth-weight infants.

  Acta paediatrica (Oslo, Norway : 1992) 20110701

• Anti-inflammatory activity of an alkaloid from Solanum trilobatum on acute and chronic inflammation models.

  Natural product research 20110701

• Induction of apoptosis in circulating angiogenic cells by microparticles.

  Arthritis and rheumatism 20110701

• Role of iPLA(2) in the regulation of Src trafficking and microglia chemotaxis.

  Traffic (Copenhagen, Denmark) 20110701

• Associations of birth weight with serum long chain polyunsaturated fatty acids in adolescents; the HELENA study.

  Atherosclerosis 20110701

• Arachidonic acid accumulates in the stromal macrophages during thymus involution in diabetes.

  Histochemistry and cell biology 20110701

• Distinctive effects of arachidonic acid and docosahexaenoic acid on neural stem /progenitor cells.

  Genes to cells : devoted to molecular & cellular mechanisms 20110701

• Amniotic fluid eicosanoids in preterm and term births: effects of risk factors for spontaneous preterm labor.

  Obstetrics and gynecology 20110701

• Potentiation of regulatory volume decrease by a p2-like receptor and arachidonic acid in american alligator erythrocytes.

  The Journal of membrane biology 20110701

• Synthesis and anti-platelet activity of obovatol derivatives.

  Archives of pharmacal research 20110701

• Activation of cytosolic phospholipase A2 downstream of the Src-phospholipase D1 (PLD1)-protein kinase C γ (PKCγ) signaling axis is required for hypoxia-induced pathological retinal angiogenesis.

  The Journal of biological chemistry 20110624

• Study of arachidonoyl specificity in two enzymes of the PI cycle.

  Journal of molecular biology 20110603

• Simultaneous quantification of total eicosapentaenoic acid, docosahexaenoic acid and arachidonic acid in plasma by high-performance liquid chromatography-tandem mass spectrometry.

  Biomedical chromatography : BMC 20110601

• Activation of group IVC phospholipase A(2) by polycyclic aromatic hydrocarbons induces apoptosis of human coronary artery endothelial cells.

  Archives of toxicology 20110601

• T-type voltage-gated calcium channels as targets for the development of novel pain therapies.

  British journal of pharmacology 20110601

• Protective effect of quercetin, EGCG, catechin and betaine against oxidative stress induced by ethanol in vitro.

  Experimental and molecular pathology 20110601

• Biphasic effect of linoleic acid on connexin 46 hemichannels.

  Pflugers Archiv : European journal of physiology 20110601

• 'Sebocytes' makeup': novel mechanisms and concepts in the physiology of the human sebaceous glands.

  Pflugers Archiv : European journal of physiology 20110601

• The effect of intravenous high-dose methylprednisolone on platelet reactivity assessed with multiple electrode aggregometry.

  Thrombosis and haemostasis 20110601

• Growth hormone enhances arachidonic acid metabolites in a growth hormone transgenic mouse.

  Lipids 20110601

• Biology of Cox-2: an application in cancer therapeutics.

  Current drug targets 20110601

• Dual anticoagulant/antiplatelet persulfated small molecules.

  European journal of medicinal chemistry 20110601

• Role of superoxide and thromboxane receptors in acute angiotensin II-induced vasoconstriction of rabbit vessels.

  American journal of physiology. Heart and circulatory physiology 20110601

• Human immunodeficiency virus type 1 clade B and C gp120 differentially induce neurotoxin arachidonic acid in human astrocytes: implications for neuroAIDS.

  Journal of neurovirology 20110601

• Fatty acid composition of common barbel (Barbus barbus) roe and evaluation of its haemolytic and cytotoxic activities.

  Toxicon : official journal of the International Society on Toxinology 20110601

• Chemical study and anti-inflammatory, analgesic and antioxidant activities of the leaves of Aristotelia chilensis (Mol.) Stuntz, Elaeocarpaceae.

  The Journal of pharmacy and pharmacology 20110601

• A role of stretch-activated potassium currents in the regulation of uterine smooth muscle contraction.

  Acta pharmacologica Sinica 20110601

• Essential fatty acid supplementation of DHA and ARA and effects on neurodevelopment across animal species: a review of the literature.

  Birth defects research. Part B, Developmental and reproductive toxicology 20110601

• Effect of polymorphism and type II diabetes on aspirin resistance in patients with unstable coronary artery disease.

  Chinese medical journal 20110601

• Generation of trans-arachidonic acid under nitrative stress is associated with upregulation of thromponsdin-1 in diabetic rats.

  Chinese medical journal 20110601

• [Therapeutic effects of larger doses of arachidonic acid added to DHA on social impairment and its relation to alterations of polyunsaturated fatty acids in individuals with autism spectrum disorders].

  Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology 20110601

• Significance of brain tissue oxygenation and the arachidonic acid cascade in stroke.

  Antioxidants & redox signaling 20110515

• 5-oxo-ETE is a major oxidative stress-induced arachidonate metabolite in B lymphocytes.

  Free radical biology & medicine 20110515

• The human megakaryocytic cell line UT-7/TPO responds to platelet agonists with intracellular Ca2+ elevation and P-selectin expression.

  Cell biology international 20110501

• Group V secretory phospholipase A2 plays a pathogenic role in myocardial ischaemia-reperfusion injury.

  Cardiovascular research 20110501

• Characterization of free radicals formed from COX-catalyzed DGLA peroxidation.

  Free radical biology & medicine 20110501

• The periodontal anaerobe Porphyromonas gingivalis induced platelet activation and increased aggregation in whole blood by rat model.

  Thrombosis research 20110501

• Reciprocal regulation of TREK-1 channels by arachidonic acid and CRH in mouse corticotropes.

  Endocrinology 20110501

• BAPA, a synthetic dual inhibitor of Factor Xa and Thrombin, extends the storage-time to a maximum of 12 hours in ADP- and 24 hours in arachidonic acid-induced impedance aggregometry.

  Scandinavian journal of clinical and laboratory investigation 20110501

• Synthesis of novel mast cell-stabilising and anti-allergic 1,2,3,4-tetrahydro-1-naphthalenols and related compounds.

  European journal of medicinal chemistry 20110501

• Enzymatic hydrolysis and extraction of arachidonic acid rich lipids from Mortierella alpina.

  Bioresource technology 20110501

• PGE2 release from tryptase-stimulated rabbit ventricular myocytes is mediated by calcium-independent phospholipase A2γ.

  Lipids 20110501

• Topical anti-inflammatory activity of quillaic acid from Quillaja saponaria Mol. and some derivatives.

  The Journal of pharmacy and pharmacology 20110501

• Platelet function assessed by whole-blood aggregometry in patients undergoing non-cardiac surgery.

  European journal of anaesthesiology 20110501

• Contribution of Ras farnesyl transferase, MAP kinase and cytochrome P-450 metabolites to endothelin-1 induced hypertension.

  Bosnian journal of basic medical sciences 20110501

• Study on the association between environmental cadmium exposure, cytochrome P450-mediated 20-HETE, heme-oxygenase-1 polymorphism and hypertension in Thai population residing in a malaria endemic areas with cadmium pollution.

  Environmental toxicology and pharmacology 20110501

• Antiplatelet effects of Cyperus rotundus and its component (+)-nootkatone.

  Journal of ethnopharmacology 20110426

• Antioxidant effect of vegetable oils containing conjugated linolenic acid isomers against induced tissue lipid peroxidation and inflammation in rat model.

  Chemico-biological interactions 20110425

• Inhibitory effect of α-lipoic acid on platelet aggregation is mediated by PPARs.

  Journal of agricultural and food chemistry 20110413

• Altered arachidonic acid cascade enzymes in postmortem brain from bipolar disorder patients.

  Molecular psychiatry 20110401

• Interaction of nitric oxide and the cytochrome P-450 system on blood pressure and renal function in the rat: dependence on sodium intake.

  Acta physiologica (Oxford, England) 20110401

• Cynomolgus macaque CYP4 isoforms are functional, metabolizing arachidonic acid.

  The Journal of veterinary medical science 20110401

• Selection of a DGLA-producing mutant of the microalga Parietochloris incisa: I. Identification of mutation site and expression of VLC-PUFA biosynthesis genes.

  Applied microbiology and biotechnology 20110401

• Activation of group VI phospholipase A2 isoforms in cardiac endothelial cells.

  American journal of physiology. Cell physiology 20110401

• Stimulation of A(₂a) adenosine receptor abolishes the inhibitory effect of arachidonic acid on the basolateral 50-pS K channel in the thick ascending limb.

  American journal of physiology. Renal physiology 20110401

• Hydrogen sulfide-induced dual vascular effect involves arachidonic acid cascade in rat mesenteric arterial bed.

  The Journal of pharmacology and experimental therapeutics 20110401

• The effects of oxidation products of arachidonic acid and n3 fatty acids on vascular and platelet function.

  Free radical research 20110401

• Role of lipoxygenase metabolites of arachidonic acid in enhanced pulmonary artery contractions of female rabbits.

  Hypertension (Dallas, Tex. : 1979) 20110401

• Increased platelet aggregation and in vivo platelet activation after granulocyte colony-stimulating factor administration. A randomised controlled trial.

  Thrombosis and haemostasis 20110401

• Residual cyclooxygenase-1 activity and epinephrine reduce the antiplatelet effect of aspirin in patients with acute myocardial infarction.

  Thrombosis and haemostasis 20110401

• A methodology for radiolabeling of the endocannabinoid 2-arachidonoylglycerol (2-AG).

  The Journal of organic chemistry 20110401

• Dietary intakes of polyunsaturated fatty acids among pregnant Mexican women.

  Maternal & child nutrition 20110401

• Eicosapolyenoic acids: novel MAMPs with reciprocal effect on oomycete-plant defense signaling networks.

  Plant signaling & behavior 20110401

• [Novel anti-cancer effects of indomethacin: exploring the cyclooxygenase-inhibition-independent effects].

  Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20110401

• Ultra-pressure liquid chromatography/tandem mass spectrometry targeted profiling of arachidonic acid and eicosanoids in human colorectal cancer.

  Rapid communications in mass spectrometry : RCM 20110330

• Anti-inflammatory activity of Sorbus commixta water extract and its molecular inhibitory mechanism.

  Journal of ethnopharmacology 20110324

• Complex regulation of the TRPM8 cold receptor channel: role of arachidonic acid release following M3 muscarinic receptor stimulation.

  The Journal of biological chemistry 20110318

• Estrogen metabolites in the release of inflammatory mediators from human amnion-derived cells.

  Life sciences 20110314

• Inhibitory activity of natural occurring antioxidants on Thiyl radical-induced trans-arachidonic acid formation.

  Journal of agricultural and food chemistry 20110309

• Marine n-3 polyunsaturated fatty acids in patients with end-stage renal failure and in subjects without kidney disease: a comparative study.

  Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 20110301

• Arachidonic acid actions on functional integrity and attenuation of the negative effects of palmitic acid in a clonal pancreatic β-cell line.

  Clinical science (London, England : 1979) 20110301

• Association of serum levels of arachidonic acid and eicosapentaenoic acid with prevalence of major adverse cardiac events after acute myocardial infarction.

  Heart and vessels 20110301

• Arachidonic acid fights palmitate: new insights into fatty acid toxicity in β-cells.

  Clinical science (London, England : 1979) 20110301

• Serum fatty acid profile in subjects with irritable bowel syndrome.

  Scandinavian journal of gastroenterology 20110301

• Diversity and distribution of microbial long-chain fatty acid biosynthetic genes in the marine environment.

  Environmental microbiology 20110301

• Ibuprofen bioconcentration and prostaglandin E2 levels in the bluntnose minnow Pimephales notatus.

  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20110301

• Reduced platelet function and role of drugs in acute gastrointestinal bleeding.

  Basic & clinical pharmacology & toxicology 20110301

• In the presence of strong P2Y12 receptor blockade, aspirin provides little additional inhibition of platelet aggregation.

  Journal of thrombosis and haemostasis : JTH 20110301

• Human prostaglandin H synthase (hPHS)-1 and hPHS-2 in amphetamine analog bioactivation, DNA oxidation, and cytotoxicity.

  Toxicological sciences : an official journal of the Society of Toxicology 20110301

• Platelet function testing in hirudin and BAPA anticoagulated blood.

  Clinical chemistry and laboratory medicine 20110301

• Valproate uncompetitively inhibits arachidonic acid acylation by rat acyl-CoA synthetase 4: relevance to valproate's efficacy against bipolar disorder.

  Biochimica et biophysica acta 20110301

• Role of arachidonic acid lipoxygenase metabolites in acetylcholine-induced relaxations of mouse arteries.

  American journal of physiology. Heart and circulatory physiology 20110301

• Upregulated arachidonic acid signalling in the olfactory bulbectomized rat model of depression.

  Neurochemistry international 20110301

• Variability and persistence of aspirin response in lower extremity peripheral arterial disease patients.

  Journal of vascular surgery 20110301

• Treatment of diabetic rats with a peroxynitrite decomposition catalyst prevents induction of renal COX-2.

  American journal of physiology. Heart and circulatory physiology 20110301

• 20-Hydroxyeicosatetraenoic acid induces apoptosis in neonatal rat cardiomyocytes through mitochondrial-dependent pathways.

  Journal of cardiovascular pharmacology 20110301

• The endocannabinoid 2-arachidonoyl-glycerol activates human neutrophils: critical role of its hydrolysis and de novo leukotriene B4 biosynthesis.

  Journal of immunology (Baltimore, Md. : 1950) 20110301

• Delayed production of arachidonic acid contributes to the delay of proteinase-activated receptor-1 (PAR1)-triggered prostaglandin E2 release in rat gastric epithelial RGM1 cells.

  Journal of cellular biochemistry 20110301

• Low-dose naproxen interferes with the antiplatelet effects of aspirin in healthy subjects: recommendations to minimize the functional consequences.

  Arthritis and rheumatism 20110301

• The effects of dietary fish oil on inflammation, fibrosis and oxidative stress associated with obstructive renal injury in rats.

  Molecular nutrition & food research 20110301

• Inhibition of soluble epoxide hydrolase confers cardioprotection and prevents cardiac cytochrome P450 induction by benzo(a)pyrene.

  Journal of cardiovascular pharmacology 20110301

• Cyclooxygenase reaction mechanism of prostaglandin H synthase from deuterium kinetic isotope effects.

  Journal of inorganic biochemistry 20110301

• Structural comparisons of arachidonic acid-induced radicals formed by prostaglandin H synthase-1 and -2.

  Journal of inorganic biochemistry 20110301

• Dietary conjugated linoleic acid isomers change the unsaturation degree of hepatic fatty acids in neutral lipids but not in polar lipids.

  Nutrition research (New York, N.Y.) 20110301

• Documentation of fatty acid profiles in lamb meat and lamb-based infant foods.

  Journal of food science 20110301

• Arachidonic acid stimulates formation of a novel complex containing nucleolin and RhoA.

  FEBS letters 20110218

• The effect of fenugreek on the gene expression of arachidonic acid metabolizing enzymes.

  Phytotherapy research : PTR 20110201

• Imaging upregulated brain arachidonic acid metabolism in HIV-1 transgenic rats.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20110201

• Hemostatic function of buffy coat platelets in additive solution treated with pathogen reduction technology.

  Transfusion 20110201

• Differences in fat content and fatty acid proportions among colostrum, transitional, and mature milk from women delivering very preterm, preterm, and term infants.

  Clinical nutrition (Edinburgh, Scotland) 20110201

• Effect of inhibitors of arachidonic acid metabolism on prostaglandin E₂ production by Candida albicans and Candida dubliniensis biofilms.

  Medical microbiology and immunology 20110201

• Dietary n-6 PUFA deprivation downregulates arachidonate but upregulates docosahexaenoate metabolizing enzymes in rat brain.

  Biochimica et biophysica acta 20110201

• Mechanisms underlying increased reactivity of pulmonary arteries contralateral to a localized high-flow anastomosis.

  The Journal of thoracic and cardiovascular surgery 20110201

• Selective eicosanoid-generating capacity of cytoplasmic phospholipase A2 in Pseudomonas aeruginosa-infected epithelial cells.

  American journal of physiology. Lung cellular and molecular physiology 20110201

• Protease-activated receptor signaling in platelets activates cytosolic phospholipase A2α differently for cyclooxygenase-1 and 12-lipoxygenase catalysis.

  Arteriosclerosis, thrombosis, and vascular biology 20110201

• Why an aspirin a day no longer keeps the doctor away ….

  Thrombosis and haemostasis 20110201

• 24-hour time-dependent aspirin efficacy in patients with stable coronary artery disease.

  Thrombosis and haemostasis 20110201

• Influence of cellular arachidonic acid levels on phospholipid remodeling and CoA-independent transacylase activity in human monocytes and U937 cells.

  Biochimica et biophysica acta 20110201

• A phospholipase A₂ from Bothrops asper snake venom activates neutrophils in culture: expression of cyclooxygenase-2 and PGE₂ biosynthesis.

  Toxicon : official journal of the International Society on Toxinology 20110201

• Synergistic action of hypoosmolarity and glutamine in inducing acute swelling of retinal glial (Müller) cells.

  Glia 20110201

• Arachidonic acid induces production of 17,20β-dihydroxy-4-pregnen-3-one (DHP) via a putative PGE2 receptor in fish follicles from the Eurasian perch.

  Lipids 20110201

• Angiotensin II regulates adrenal vascular tone through zona glomerulosa cell-derived EETs and DHETs.

  Hypertension (Dallas, Tex. : 1979) 20110201

• Relation of aspirin failure to clinical outcome and to platelet response to aspirin in patients with acute myocardial infarction.

  The American journal of cardiology 20110201

• Arachidonic acid pathway members PLA2G7, HPGD, EPHX2, and CYP4F8 identified as putative novel therapeutic targets in prostate cancer.

  The American journal of pathology 20110201

• Central mechanism underlying pressor and bradycardic effect of intracerebroventricularly injected arachidonic acid.

  Canadian journal of physiology and pharmacology 20110201

• Regulation of the expression of cyclooxygenases and production of prostaglandin I₂ and E₂ in human coronary artery endothelial cells by curcumin.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20110201

• Different roles of zinc plus arachidonic acid on insulin sensitivity between high fructose- and high fat-fed rats.

  Life sciences 20110131

• A bifunctional role for group IIA secreted phospholipase A2 in human rheumatoid fibroblast-like synoviocyte arachidonic acid metabolism.

  The Journal of biological chemistry 20110128

• Arzanol, a prenylated heterodimeric phloroglucinyl pyrone, inhibits eicosanoid biosynthesis and exhibits anti-inflammatory efficacy in vivo.

  Biochemical pharmacology 20110115

• Melittin stimulates fatty acid release through non-phospholipase-mediated mechanisms and interacts with the dopamine transporter and other membrane-spanning proteins.

  European journal of pharmacology 20110115

• Inducible COX-2 dominates over COX-1 in prostacyclin biosynthesis: mechanisms of COX-2 inhibitor risk to heart disease.

  Life sciences 20110103

• Platelet aggregability is modulated by eNOS locus in non-type 2 diabetic patients with acute coronary syndrome.

  Nutrition, metabolism, and cardiovascular diseases : NMCD 20110101

• Enhanced generation of megakaryocytes from umbilical cord blood-derived CD34(+) cells expanded in the presence of two nutraceuticals, docosahexanoic acid and arachidonic acid, as supplements to the cytokine-containing medium.

  Cytotherapy 20110101

• Attention among very low birth weight infants following early supplementation with docosahexaenoic and arachidonic acid.

  Acta paediatrica (Oslo, Norway : 1992) 20110101

• Selective regulation of UGT1A1 and SREBP-1c mRNA expression by docosahexaenoic, eicosapentaenoic, and arachidonic acids.

  Journal of cellular physiology 20110101

• Poxytrins, a class of oxygenated products from polyunsaturated fatty acids, potently inhibit blood platelet aggregation.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20110101

• Amelioration of cisplatin nephrotoxicity by genetic or pharmacologic blockade of prostaglandin synthesis.

  Kidney international 20110101

• Targeting cyclooxygenases-1 and -2 in neuroinflammation: Therapeutic implications.

  Biochimie 20110101

• Role of cytochrome P450 enzymes in the bioactivation of polyunsaturated fatty acids.

  Biochimica et biophysica acta 20110101

• Maternal arachidonic acid supplementation improves neurodevelopment in young adult offspring from rat dams with and without diabetes.

  Prostaglandins, leukotrienes, and essential fatty acids 20110101

• Role of arachidonic acid-derived metabolites in the control of pulmonary arterial pressure and hypoxic pulmonary vasoconstriction in rats.

  British journal of anaesthesia 20110101

• Nonenzymatic free radical-catalyzed generation of 15-deoxy-Δ(12,14)-prostaglandin J₂-like compounds (deoxy-J₂-isoprostanes) in vivo.

  Journal of lipid research 20110101

• Activation of the acute inflammatory response alters cytochrome P450 expression and eicosanoid metabolism.

  Drug metabolism and disposition: the biological fate of chemicals 20110101

• Effect of platelet turnover on whole blood platelet aggregation in patients with coronary artery disease.

  Journal of thrombosis and haemostasis : JTH 20110101

• Clopidogrel discontinuation and platelet reactivity following coronary stenting.

  Journal of thrombosis and haemostasis : JTH 20110101

• Varying coefficient function models to explore interactions between maternal nutritional status and prenatal methylmercury toxicity in the Seychelles Child Development Nutrition Study.

  Environmental research 20110101

• Anti-inflammatory effects of chronic aspirin on brain arachidonic acid metabolites.

  Neurochemical research 20110101

• Leukotriene B4 receptors: novel roles in immunological regulations.

  Advances in enzyme regulation 20110101

• A high omega-3 fatty acid diet has different effects on early and late stage myeloid progenitors.

  Lipids 20110101

• Automated targeting analysis of eicosanoid inflammation biomarkers in human serum and in the exometabolome of stem cells by SPE-LC-MS/MS.

  Analytical and bioanalytical chemistry 20110101

• A highly constrained cyclic (S,S)-CDC- peptide is a potent inhibitor of carotid artery thrombosis in rabbits.

  Platelets 20110101

• Statins have an early antiplatelet effect in patients with acute myocardial infarction.

  Platelets 20110101

• Management of type-2 diabetes with anti-platelet therapies: special reference to aspirin.

  Frontiers in bioscience (Scholar edition) 20110101

• [Anti-atherosclerotic effect of fibrates and eicosapentaenoic acid].

  Nihon rinsho. Japanese journal of clinical medicine 20110101

• Platelet reactivity in diabetic patients subjected to acute exercise stress test.

  Cardiovascular revascularization medicine : including molecular interventions 20110101

• Polyunsaturated fatty acids reduce fatty acid synthase and hydroxy-methyl-glutaryl CoA-reductase gene expression and promote apoptosis in HepG2 cell line.

  Lipids in health and disease 20110101

• Use of metabolomic profiling in the study of arachidonic acid metabolism in cardiovascular disease.

  Congestive heart failure (Greenwich, Conn.) 20110101

• Effects of eicosapentaenoic acid on asymmetric dimethylarginine in patients in the chronic phase of cerebral infarction: a preliminary study.

  Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 20110101

• The influence of supplemental docosahexaenoic and arachidonic acids during pregnancy and lactation on neurodevelopment at eighteen months.

  Prostaglandins, leukotrienes, and essential fatty acids 20110101

• Impact of polyunsaturated fatty acids on oxidized low density lipoprotein-induced U937 cell apoptosis.

  Journal of atherosclerosis and thrombosis 20110101

• Characterization of bovine immortalized luteal endothelial cells: action of cytokines on production and content of arachidonic acid metabolites.

  Reproductive biology and endocrinology : RB&E 20110101

• DHA improves cognition and prevents dysfunction of entorhinal cortex neurons in 3xTg-AD mice.

  PloS one 20110101

• Multiple phospholipase A2 enzymes participate in the inflammatory process in osteoarthritic cartilage.

  Scandinavian journal of rheumatology 20110101

• Age-related changes of dietary intake and blood eicosapentaenoic acid, docosahexaenoic acid, and arachidonic acid levels in Japanese men and women.

  Prostaglandins, leukotrienes, and essential fatty acids 20110101

• Using the medical food flavocoxid [corrected] in managing osteoarthritis.

  Journal of pain & palliative care pharmacotherapy 20110101

• Prolonged exposure of cortical neurons to oligomeric amyloid-β impairs NMDA receptor function via NADPH oxidase-mediated ROS production: protective effect of green tea (-)-epigallocatechin-3-gallate.

  ASN neuro 20110101

• Pharmacology in health foods: effects of arachidonic acid and docosahexaenoic acid on the age-related decline in brain and cardiovascular system function.

  Journal of pharmacological sciences 20110101

• Associations of long-chain polyunsaturated fatty acid concentrations with birth outcome in term Indian mothers and their neonates.

  American journal of human biology : the official journal of the Human Biology Council 20110101

• Adenosine inhibits the release of arachidonic acid in activated human peripheral mononuclear cells. A proposed model for physiologic and pathologic regulation in systemic lupus erythematosus.

  TheScientificWorldJournal 20110101

• L-type calcium channel β subunit modulates angiotensin II responses in cardiomyocytes.

  Channels (Austin, Tex.) 20110101

• Short-term exposure of platelets to glucose impairs inhibition of platelet aggregation by cyclooxygenase inhibitors.

  Platelets 20110101

• High extracellular Ca2+ stimulates Ca2+-activated Cl- currents in frog parathyroid cells through the mediation of arachidonic acid cascade.

  PloS one 20110101

• Overexpression of CYP3A4, but not of CYP2D6, promotes hypoxic response and cell growth of Hep3B cells.

  Drug metabolism and pharmacokinetics 20110101

• The impact of FADS genetic variants on ω6 polyunsaturated fatty acid metabolism in African Americans.

  BMC genetics 20110101

• Increased Δ5- and Δ6-desaturase, cyclooxygenase-2, and lipoxygenase-5 expression and activity are associated with fatty acid and eicosanoid changes in cystic fibrosis.

  Biochimica et biophysica acta 20110101

• [Dynamics of morphological structures of platelets in patients with ischemic heart disease in dependence on blood levels of fatty acids].

  Kardiologiia 20110101

• [Systematic analysis of molecular mechanisms of action of omega-3 polyunsaturated fatty acids on arrhythmia].

  Kardiologiia 20110101

• Liver conversion of docosahexaenoic and arachidonic acids from their 18-carbon precursors in rats on a DHA-free but α-LNA-containing n-3 PUFA adequate diet.

  Biochimica et biophysica acta 20110101

• The relation between the omega-3 index and arachidonic acid is bell shaped: synergistic at low EPA+DHA status and antagonistic at high EPA+DHA status.

  Prostaglandins, leukotrienes, and essential fatty acids 20110101

• Severe alterations in lipid composition of frontal cortex lipid rafts from Parkinson's disease and incidental Parkinson's disease.

  Molecular medicine (Cambridge, Mass.) 20110101

• The TIP30 protein complex, arachidonic acid and coenzyme A are required for vesicle membrane fusion.

  PloS one 20110101

• Flavocoxid inhibits phospholipase A2, peroxidase moieties of the cyclooxygenases (COX), and 5-lipoxygenase, modifies COX-2 gene expression, and acts as an antioxidant.

  Mediators of inflammation 20110101

• Inhibitory effects of 1,3-bis-(2-substituted-phenyl)-propane-1,3-dione, β-diketone structural analogues of curcumin, on chemical-induced tumor promotion and inflammation in mouse skin.

  Food & function 20110101

• Relationship between coronary plaque vulnerability and serum n-3/n-6 polyunsaturated fatty acid ratio.

  Circulation journal : official journal of the Japanese Circulation Society 20110101

• Regulation of the arachidonic acid mobilization in macrophages by combustion-derived particles.

  Particle and fibre toxicology 20110101

• Cell signaling and neurotoxicity: ³H-arachidonic acid release (phospholipase A₂) in cerebellar granule neurons.

  Methods in molecular biology (Clifton, N.J.) 20110101

• Incorporation of n-3 PUFA and γ-linolenic acid in blood lipids and red blood cell lipids together with their influence on disease activity in patients with chronic inflammatory arthritis--a randomized controlled human intervention trial.

  Lipids in health and disease 20110101

• Hypertension is associated with marked alterations in sphingolipid biology: a potential role for ceramide.

  PloS one 20110101

• Increased neuroinflammatory and arachidonic acid cascade markers, and reduced synaptic proteins, in brain of HIV-1 transgenic rats.

  Journal of neuroinflammation 20110101

• Quercetin suppresses cyclooxygenase-2 expression and angiogenesis through inactivation of P300 signaling.

  PloS one 20110101

• Exogenous HIV-1 Nef upsets the IFN-γ-induced impairment of human intestinal epithelial integrity.

  PloS one 20110101

• The CpG island methylation regulated expression of endothelial proangiogenic genes in response to β-carotene and arachidonic acid.

  Nutrition and cancer 20110101

• [Mass spectrometry-based quantitative analysis and biomarker discovery].

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20110101

• MicroRNA profile of polyunsaturated fatty acid treated glioma cells reveal apoptosis-specific expression changes.

  Lipids in health and disease 20110101

• Arachidonic acid randomizes endothelial cell motion and regulates adhesion and migration.

  PloS one 20110101

• [The role of leucotrienes in coronary artery disease and new therapy perspectives].

  Kardiologia polska 20110101

• Platelet adhesion and degranulation induce pro-survival and pro-angiogenic signalling in ovarian cancer cells.

  PloS one 20110101

• Cellular lipid extraction for targeted stable isotope dilution liquid chromatography-mass spectrometry analysis.

  Journal of visualized experiments : JoVE 20110101

• Inverse association between trans isomeric and long-chain polyunsaturated fatty acids in pregnant women and their newborns: data from three European countries.

  Annals of nutrition & metabolism 20110101

• Omega-3 fatty acid deficiency during brain maturation reduces neuronal and behavioral plasticity in adulthood.

  PloS one 20110101

• Pathophysiology of chronic rhinosinusitis with nasal polyp.

  American journal of rhinology & allergy 20110101

• Supplementation of arachidonic acid-enriched oil increases arachidonic acid contents in plasma phospholipids, but does not increase their metabolites and clinical parameters in Japanese healthy elderly individuals: a randomized controlled study.

  Lipids in health and disease 20110101

• [Cerebrovascular effects of GABA conjugate with arachidonic acid under conditions of separate and combined vascular pathology of brain and heart].

  Eksperimental'naia i klinicheskaia farmakologiia 20110101

• [Relationship between EPA or EPA/AA and arteriosclerosis in elderly patients over 80 years old].

  Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 20110101

• Anti-inflammatory and redox-protective activities of citronellal.

  Biological research 20110101

• [Changes in the fatty acid composition of blood cell membranes in children with inflammatory diseases].

  Biomeditsinskaia khimiia 20110101

• [Biosynthesis of arachidonic acid by micromycetes (review)].

  Prikladnaia biokhimiia i mikrobiologiia 20110101

• Inactivation of lipid glyceryl ester metabolism in human THP1 monocytes/macrophages by activated organophosphorus insecticides: role of carboxylesterases 1 and 2.

  Chemical research in toxicology 20101220

• Filtration assay for arachidonic acid release.

  Analytical biochemistry 20101215

• Melatonin: a pleiotropic molecule regulating inflammation.

  Biochemical pharmacology 20101215

• Glybenclamide: an antidiabetic with in vivo antithrombotic activity.

  European journal of pharmacology 20101215

• Epoxyeicosatrienoic acid agonist regulates human mesenchymal stem cell-derived adipocytes through activation of HO-1-pAKT signaling and a decrease in PPARγ.

  Stem cells and development 20101201

• Lipoxygenase-derived hydroxyeicosatetraenoic acids--novel perioperative markers of early post-transplant allograft function?

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20101201

• Long-term effects of gestational diabetes on offspring health are more pronounced in skeletal growth than body composition and glucose tolerance.

  The British journal of nutrition 20101201

• Inhibitory effect of hericenone B from Hericium erinaceus on collagen-induced platelet aggregation.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20101201

• Determinants of the proinflammatory action of ambient particulate matter in immortalized murine macrophages.

  Environmental health perspectives 20101201

• Palmitate protects hepatocytes from oxidative stress and triacylglyceride accumulation by stimulation of nitric oxide synthesis in the presence of high glucose and insulin concentration.

  Free radical research 20101201

• Arachidonic acid pools of rat kidney cell nuclei.

  Molecular and cellular biochemistry 20101201

• Expression of proliferative and inflammatory markers in a full-thickness human skin equivalent following exposure to the model sulfur mustard vesicant, 2-chloroethyl ethyl sulfide.

  Toxicology and applied pharmacology 20101201

• Observation of an unusual electronically distorted semiquinone radical of PCB metabolites in the active site of prostaglandin H synthase-2.

  Chemosphere 20101201

• Cytochrome P450-derived eicosanoids: the neglected pathway in cancer.

  Cancer metastasis reviews 20101201

• An association between dietary arachidonic acid, measured in adipose tissue, and ulcerative colitis.

  Gastroenterology 20101201

• Enhanced cyclooxygenase 2-mediated vasorelaxation in coronary arteries from insulin-resistant obese Zucker rats.

  Atherosclerosis 20101201

• Lutein is a competitive inhibitor of cytosolic Ca²+-dependent phospholipase A₂.

  The Journal of pharmacy and pharmacology 20101201

• Lysine 63-linked ubiquitination is important for arachidonic acid-induced cellular adhesion and migration.

  Biochemistry and cell biology = Biochimie et biologie cellulaire 20101201

• Inconsistency of different methods for assessing ex vivo platelet function: relevance for the detection of aspirin resistance.

  Haematologica 20101201

• ω-3 fatty acids suppress inflammatory cytokine production by macrophages and hepatocytes.

  Journal of pediatric surgery 20101201

• A simple method of supplementation of omega-3 polyunsaturated fatty acids: use of fortified yogurt in healthy volunteers.

  Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition 20101201

• Protective effect of dietary n-3 polyunsaturated fatty acids on myocardial resistance to ischemia-reperfusion injury in rats.

  Nutrition research (New York, N.Y.) 20101201

• Exhaled breath condensates in asthma: diagnostic and therapeutic implications.

  Journal of breath research 20101201

• Melittin promotes exocytosis in neuroendocrine cells through the activation of phospholipase A₂.

  Regulatory peptides 20101130

• Analysis of epoxyeicosatrienoic acids by chiral liquid chromatography/electron capture atmospheric pressure chemical ionization mass spectrometry using [13C]-analog internal standards.

  Rapid communications in mass spectrometry : RCM 20101130

• Brain fatty acid-binding protein and omega-3/omega-6 fatty acids: mechanistic insight into malignant glioma cell migration.

  The Journal of biological chemistry 20101119

• Excessive ingestion of long-chain polyunsaturated fatty acids during developmental stage causes strain- and sex-dependent eye abnormalities in mice.

  Biochemical and biophysical research communications 20101112

• Inhibitory effects of phylligenin and quebrachitol isolated from Mitrephora vulpina on platelet activating factor receptor binding and platelet aggregation.

  Molecules (Basel, Switzerland) 20101103

• Inhibition of the cation channel TRPV4 improves bladder function in mice and rats with cyclophosphamide-induced cystitis.

  Proceedings of the National Academy of Sciences of the United States of America 20101102

• Epoxyeicosatrienoates are the dominant eicosanoids in human lungs upon microbial challenge.

  The European respiratory journal 20101101

• Critical role of cytosolic phospholipase A2{alpha} in bronchial mucus hypersecretion in CFTR-deficient mice.

  The European respiratory journal 20101101

• Dietary DHA: time course of tissue uptake and effects on cytokine secretion in mice.

  The British journal of nutrition 20101101

• Inhibition of arachidonic acid metabolism decreases tumor cell invasion and matrix metalloproteinase expression.

  Prostaglandins & other lipid mediators 20101101

• Linoleic acid supplementation results in increased arachidonic acid and eicosanoid production in CF airway cells and in cftr-/- transgenic mice.

  American journal of physiology. Lung cellular and molecular physiology 20101101

• Newly synthetic ceramide-1-phosphate analogs; their uptake, intracellular localization, and roles as an inhibitor of cytosolic phospholipase A(2)α and inducer of cell toxicity.

  Biochemical pharmacology 20101101

• The moss Physcomitrella patens contains cyclopentenones but no jasmonates: mutations in allene oxide cyclase lead to reduced fertility and altered sporophyte morphology.

  The New phytologist 20101101

• TCDD induced pericardial edema and relative COX-2 expression in medaka (Oryzias Latipes) embryos.

  Toxicological sciences : an official journal of the Society of Toxicology 20101101

• Long chain polyunsaturated fatty acids in mothers of preterm babies.

  Journal of perinatal medicine 20101101

• Atorvastatin inhibits oxidative stress via adiponectin-mediated NADPH oxidase down-regulation in hypercholesterolemic patients.

  Atherosclerosis 20101101

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101

• Multiple roles of protein kinase a in arachidonic acid-mediated Ca2+ entry and tumor-derived human endothelial cell migration.

  Molecular cancer research : MCR 20101101

• [Prostaglandin synthases with thioredoxin domain].

  Seikagaku. The Journal of Japanese Biochemical Society 20101101

• Inhibition of cyclooxygenase activity of prostaglandin-H-synthase by excess substrate (molecular oxygen).

  Biochemistry. Biokhimiia 20101101

• Arachidonic acid-metabolizing cytochrome P450 enzymes are targets of {omega}-3 fatty acids.

  The Journal of biological chemistry 20101022

• A liquid chromatography-tandem mass spectrometry method for measurement of N-modified phosphatidylethanolamines.

  Analytical biochemistry 20101015

• Synthesis and biological activities of transition metal complexes based on acetylsalicylic acid as neo-anticancer agents.

  Journal of medicinal chemistry 20101014

• Reduced brain content of arachidonic acid and docosahexaenoic acid is related to the severity of liver fibrosis.

  Digestive diseases and sciences 20101001

• Selective deficits in erythrocyte docosahexaenoic acid composition in adult patients with bipolar disorder and major depressive disorder.

  Journal of affective disorders 20101001

• Platelet activation patterns in platelet size sub-populations: differential responses to aspirin in vitro.

  Journal of thrombosis and thrombolysis 20101001

• High potassium intake enhances the inhibitory effect of 11,12-EET on ENaC.

  Journal of the American Society of Nephrology : JASN 20101001

• Effect of dietary mixture of gallic acid and linoleic acid on antioxidative potential and quality of breast meat from broilers.

  Meat science 20101001

• Quantifying conversion of linoleic to arachidonic and other n-6 polyunsaturated fatty acids in unanesthetized rats.

  Journal of lipid research 20101001

• In utero exposure to maternal diabetes impairs vascular expression of prostacyclin receptor in rat offspring.

  Diabetes 20101001

• Treatment with docosahexaenoic acid, but not eicosapentaenoic acid, delays Ca2+-induced mitochondria permeability transition in normal and hypertrophied myocardium.

  The Journal of pharmacology and experimental therapeutics 20101001

• Promotion of interferon-gamma production by natural killer cells via suppression of murine peritoneal macrophage prostaglandin E₂ production using intravenous anesthetic propofol.

  International immunopharmacology 20101001

• Limited effect of dietary saturated fat on plasma saturated fat in the context of a low carbohydrate diet.

  Lipids 20101001

• Prostaglandin E2 and prostaglandin F2α differentially modulate matrix metabolism of human nucleus pulposus cells.

  Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20101001

• Group X secretory phospholipase A2 negatively regulates ABCA1 and ABCG1 expression and cholesterol efflux in macrophages.

  Arteriosclerosis, thrombosis, and vascular biology 20101001

• The 5-lipoxygenase inhibitor, zileuton, suppresses prostaglandin biosynthesis by inhibition of arachidonic acid release in macrophages.

  British journal of pharmacology 20101001

• 20-hydroxyeicosatetraeonic acid: a new target for the treatment of hypertension.

  Journal of cardiovascular pharmacology 20101001

• Arachidonic acid: an evolutionarily conserved signaling molecule modulates plant stress signaling networks.

  The Plant cell 20101001

• Effect of a fish oil-containing beverage on changes in plasma lipid fatty acids in patients with malabsorption.

  Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition 20101001

• Erythrocyte membrane fatty acid content in infants consuming formulas supplemented with docosahexaenoic acid (DHA) and arachidonic acid (ARA): an observational study.

  Maternal & child nutrition 20101001

• High α-linolenic acid and fish oil ingestion promotes ovulation to the same extent in rats.

  Nutrition research (New York, N.Y.) 20101001

• PUFAs enhance oxidative stress and apoptosis in tumour cells exposed to hypericin-mediated PDT.

  Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20100924

• Comparative fatty acid profiles of wild and farmed tropical freshwater fish rohu (Labeo rohita).

  Fish physiology and biochemistry 20100901

• The serotonin 5-HT(2A) receptor agonist TCB-2: a behavioral and neurophysiological analysis.

  Psychopharmacology 20100901

• Niacin sensitivity and the arachidonic acid pathway in schizophrenia.

  Schizophrenia research 20100901

• Lipidomics reveals membrane lipid remodelling and release of potential lipid mediators during early stress responses in a murine melanoma cell line.

  Biochimica et biophysica acta 20100901

• The human megakaryocytic cell line UT-7/TPO expresses functional platelet agonist signals mediated through GPVI and thromboxane receptor.

  Cell biology international 20100901

• Effects of betahistine at histamine H3 receptors: mixed inverse agonism/agonism in vitro and partial inverse agonism in vivo.

  The Journal of pharmacology and experimental therapeutics 20100901

• Evaluation of platelet function and pharmacological platelet inhibition in patients with myeloproliferative disorders using multiple electrode aggregometry.

  Thrombosis research 20100901

• Polyunsaturated fatty acids deficits are associated with psychotic state and negative symptoms in patients with schizophrenia.

  Prostaglandins, leukotrienes, and essential fatty acids 20100901

• Fatty acid metabolism in cystic fibrosis.

  Prostaglandins, leukotrienes, and essential fatty acids 20100901

• Platelet reactivity and pregnancy loss.

  American journal of obstetrics and gynecology 20100901

• Methyl esterase 1 (StMES1) is required for systemic acquired resistance in potato.

  Molecular plant-microbe interactions : MPMI 20100901

• [Significance of platelet function tests].

  Der Internist 20100901

• COX-mediated endothelium-dependent contractions: from the past to recent discoveries.

  Acta pharmacologica Sinica 20100901

• Homoisoflavanone inhibits UVB-induced skin inflammation through reduced cyclooxygenase-2 expression and NF-kappaB nuclear localization.

  Journal of dermatological science 20100901

• Arachidonic acid, eicosanoids, and fracture repair.

  Journal of orthopaedic trauma 20100901

• [Progress in production of arachidonic acid by Mortierella alpina and genetic modification].

  Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20100901

• Long-chain polyunsaturated fatty acids in inborn errors of metabolism.

  Nutrients 20100901

• Arachidonic acid inhibits neuronal nitric oxide synthase elicited by proinflammatory stimuli and promotes astrocyte survival with both exogenous and endogenous peroxynitrite via different mechanisms.

  Journal of neuroscience research 20100815

• Determination of double bond location in fatty acids by manganese adduction and electron induced dissociation.

  Analytical chemistry 20100815

• Location, location, location: compartmentalization of early events in leukotriene biosynthesis.

  The Journal of biological chemistry 20100813

• Topical anti-inflammatory activity of body fat from the lizard Tupinambis merianae.

  Journal of ethnopharmacology 20100809

• Measurement of platelet function in dogs using a novel impedance aggregometer.

  Veterinary journal (London, England : 1997) 20100801

• Gender differences in platelet aggregation in healthy individuals.

  Journal of thrombosis and thrombolysis 20100801

• Enzymes involved in the conversion of arachidonic acid to eicosanoids in the skin of atopic dogs.

  Experimental dermatology 20100801

• Cerebrovascular responses in mice deficient in the potassium channel, TREK-1.

  American journal of physiology. Regulatory, integrative and comparative physiology 20100801

• Paracoccidioides brasiliensis uses endogenous and exogenous arachidonic acid for PGE x production.

  Mycopathologia 20100801

• PIBF: the double edged sword. Pregnancy and tumor.

  American journal of reproductive immunology (New York, N.Y. : 1989) 20100801

• Extracellular-derived calcium does not initiate in vivo neurotransmission involving docosahexaenoic acid.

  Journal of lipid research 20100801

• Inflammatory parameters in Caco-2 cells: effect of stimuli nature, concentration, combination and cell differentiation.

  Toxicology in vitro : an international journal published in association with BIBRA 20100801

• Advanced glycation end products inhibit Na+ K+ ATPase in proximal tubule epithelial cells: role of cytosolic phospholipase A2alpha and phosphatidylinositol 4-phosphate 5-kinase gamma.

  Biochimica et biophysica acta 20100801

• Activation of TRPC6 channels promotes endocannabinoid biosynthesis in neuronal CAD cells.

  Neurochemistry international 20100801

• Peroxisome proliferation activation receptor alpha modulation of Ca2+-regulated exocytosis via arachidonic acid in guinea-pig antral mucous cells.

  Experimental physiology 20100801

• The role of TREK-1 in cerebrovascular regulation remains elusive: focus on 'Cerebrovascular responses in mice deficient in the potassium channel, TREK-1'.

  American journal of physiology. Regulatory, integrative and comparative physiology 20100801

• High on-treatment platelet reactivity by more than one agonist predicts 12-month follow-up cardiovascular death and non-fatal myocardial infarction in acute coronary syndrome patients receiving coronary stenting.

  Thrombosis and haemostasis 20100801

• Development of a high-throughput ELISA assay for platelet function testing using platelet-rich plasma or whole blood.

  Thrombosis and haemostasis 20100801

• Aspirin resistance with genetic dyslipidemia: contribution of vascular thromboxane generation.

  Physiological genomics 20100801

• Endothelium-derived vasoactive factors and hypertension: possible roles in pathogenesis and as treatment targets.

  Current hypertension reports 20100801

• Antimicrobial activity of n-6, n-7 and n-9 fatty acids and their esters for oral microorganisms.

  Archives of oral biology 20100801

• Participation of the endocannabinoid system in lipopolysaccharide-induced inhibition of salivary secretion.

  Archives of oral biology 20100801

• Phospholipase A2 and arachidonic acid in Alzheimer's disease.

  Biochimica et biophysica acta 20100801

• Low-dose arachidonic acid intake increases erythrocytes and plasma arachidonic acid in young women.

  Prostaglandins, leukotrienes, and essential fatty acids 20100801

• The inhibitory effect of celecoxib on mouse hepatoma H22 cell line on the arachidonic acid metabolic pathway.

  Biochemistry and cell biology = Biochimie et biologie cellulaire 20100801

• Endothelin-1 induced vascular smooth muscle cell proliferation is mediated by cytochrome p-450 arachidonic acid metabolites.

  Bosnian journal of basic medical sciences 20100801

• [Influence of new 1,3,4-thiadiazines on platelet aggregation in vitro and ex vivo].

  Eksperimental'naia i klinicheskaia farmakologiia 20100801

• Novel thienylacylhydrazone derivatives inhibit platelet aggregation through cyclic nucleotides modulation and thromboxane A2 synthesis inhibition.

  European journal of pharmacology 20100725

• P2X4 receptors mediate PGE2 release by tissue-resident macrophages and initiate inflammatory pain.

  The EMBO journal 20100721

• Anti-inflammatory effect of crude extract and isolated compounds from Baccharis illinita DC in acute skin inflammation.

  Journal of ethnopharmacology 20100720

• Structural basis of fatty acid substrate binding to cyclooxygenase-2.

  The Journal of biological chemistry 20100716

• RNA editing modulates the binding of drugs and highly unsaturated fatty acids to the open pore of Kv potassium channels.

  The EMBO journal 20100707

• Endothelial cell prostaglandin I(2) and platelet-activating factor production are markedly attenuated in the calcium-independent phospholipase A(2)beta knockout mouse.

  Biochemistry 20100706

• Platelet function recovery after cessation of aspirin: preliminary study of volunteers and surgical patients.

  European journal of anaesthesiology 20100701

• Decrease in expression or activity of cytosolic phospholipase A2alpha increases cyclooxygenase-1 action: A cross-talk between key enzymes in arachidonic acid pathway in prostate cancer cells.

  Biochimica et biophysica acta 20100701

• Uptake of dihomo-gamma-linolenic acid by murine macrophages increases series-1 prostaglandin release following lipopolysaccharide treatment.

  Prostaglandins, leukotrienes, and essential fatty acids 20100701

• mRNA levels of enzymes and receptors implicated in arachidonic acid metabolism in gliomas.

  Clinical biochemistry 20100701

• Effect of visual marbling on sensory properties and quality traits of pork loin.

  Meat science 20100701

• Human milk fatty acids from lactating mothers of preterm infants: a study revealing wide intra- and inter-individual variation.

  Prostaglandins, leukotrienes, and essential fatty acids 20100701

• Role of arachidonic acid, lipoxygenase, and mitochondrial depolarization in reperfusion arrhythmias.

  American journal of physiology. Heart and circulatory physiology 20100701

• Alpha-synuclein sequesters arachidonic acid to modulate SNARE-mediated exocytosis.

  EMBO reports 20100701

• Quercetin potentiates UVB-Induced c-Fos expression: implications for its use as a chemopreventive agent.

  Cancer prevention research (Philadelphia, Pa.) 20100701

• The membrane-bound state of K2P potassium channels.

  Journal of the American Chemical Society 20100616

• Chronic imipramine but not bupropion increases arachidonic acid signaling in rat brain: is this related to 'switching' in bipolar disorder?

  Molecular psychiatry 20100601

• Inactivity-mediated insulin resistance is associated with upregulated pro-inflammatory fatty acids in human cell membranes.

  Clinical nutrition (Edinburgh, Scotland) 20100601

• Lipidomic approaches to the study of phospholipase A2-regulated phospholipid fatty acid incorporation and remodeling.

  Biochimie 20100601

• Measurement of platelet aggregation in ovine blood using a new impedance aggregometer.

  Veterinary clinical pathology 20100601

• Increased macrophage cholesterol biosynthesis and decreased cellular paraoxonase 2 (PON2) expression in Delta6-desaturase knockout (6-DS KO) mice: beneficial effects of arachidonic acid.

  Atherosclerosis 20100601

• Changes in fatty acid profiles in testis and spermatozoa of red deer exposed to metal pollution.

  Reproductive toxicology (Elmsford, N.Y.) 20100601

• Structures and mechanisms of enzymes in the leukotriene cascade.

  Biochimie 20100601

• High level production of adrenic acid in Physcomitrella patens using the algae Pavlova sp. Delta(5)-elongase gene.

  Bioresource technology 20100601

• Differential effect of chondroitin-4-sulfate on the immediate and delayed prostaglandin E2 release from osteoblasts.

  Prostaglandins & other lipid mediators 20100601

• Toxoplasma gondii: expression of GRA1 gene in endoplasmic reticulum promotes both growth and adherence and modulates intracellular calcium release in macrophages.

  Experimental parasitology 20100601

• Conjugated linoleic acid suppresses colon carcinogenesis in azoxymethane-pretreated rats with long-term feeding of diet containing beef tallow.

  Journal of gastroenterology 20100601

• Type-IIA secreted phospholipase A2 is an endogenous antibiotic-like protein of the host.

  Biochimie 20100601

• Asymmetric acetylation of the cyclooxygenase-2 homodimer by aspirin and its effects on the oxygenation of arachidonic, eicosapentaenoic, and docosahexaenoic acids.

  Molecular pharmacology 20100601

• Review article: epoxyeicosatrienoic acids: novel mediators of cardioprotection.

  Journal of cardiovascular pharmacology and therapeutics 20100601

• Arachidonic acid promotes epithelial-to-mesenchymal-like transition in mammary epithelial cells MCF10A.

  European journal of cell biology 20100601

• Prostaglandin-E2 is produced by adult human epidermal melanocytes in response to UVB in a melanogenesis-independent manner.

  Pigment cell & melanoma research 20100601

• A comparison of platelet function tests and thromboxane metabolites to evaluate aspirin response in healthy individuals and patients with coronary artery disease.

  Thrombosis and haemostasis 20100601

• Angiotensin II-dependent growth of vascular smooth muscle cells requires transactivation of the epidermal growth factor receptor via a cytosolic phospholipase A(2)-mediated release of arachidonic acid.

  Archives of biochemistry and biophysics 20100601

• Elucidation of mechanisms of the reciprocal cross talk between gonadotropin-releasing hormone and prostaglandin receptors.

  Endocrinology 20100601

• Near-infrared spectroscopy and partial least-squares regression for determination of arachidonic acid in powdered oil.

  Lipids 20100601

• Lymphocytes transfer [(14)C]-labeled fatty acids to skeletal muscle in culture; modulation by exercise.

  Cell biochemistry and function 20100601

• Bio molecular considerations in major depression and ischemic cardiovascular disease.

  Central nervous system agents in medicinal chemistry 20100601

• [Effect of Mortierlla isabellina delta5-desaturases gene on arachidonic acid synthesis].

  Wei sheng wu xue bao = Acta microbiologica Sinica 20100601

• [Detection and analysis on plasma metabolomics in patient with coronary heart disease of Xin-blood stasis syndrome pattern].

  Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20100601

• Palm oil-derived natural vitamin E alpha-tocotrienol in brain health and disease.

  Journal of the American College of Nutrition 20100601

• UCP3 translocates lipid hydroperoxide and mediates lipid hydroperoxide-dependent mitochondrial uncoupling.

  The Journal of biological chemistry 20100528

• Insights into the mechanism of binding of arachidonic acid to mammalian 15-lipoxygenases.

  The journal of physical chemistry. B 20100527

• Intestinal preconditioning ameliorates ischemia-reperfusion induced acute lung injury in rats: an experimental study.

  The Journal of surgical research 20100515

• Modulation of arachidonic and linoleic acid metabolites in myeloperoxidase-deficient mice during acute inflammation.

  Free radical biology & medicine 20100515

• A LC-MS-based method for quantification of biomarkers from serum of allergic rats.

  Molecules (Basel, Switzerland) 20100507

• Secretory phospholipase A2 type III enhances alpha-secretase-dependent amyloid precursor protein processing through alterations in membrane fluidity.

  Journal of lipid research 20100501

• Binding of arachidonic acid and two flavonoid inhibitors to human 12- and 15-lipoxygenases: a steered molecular dynamics study.

  Journal of molecular modeling 20100501

• Marked elevations in pro-inflammatory polyunsaturated fatty acid metabolites in females with irritable bowel syndrome.

  Journal of lipid research 20100501

• Significance of lipid mediators in corneal injury and repair.

  Journal of lipid research 20100501

• AMPK-mediated GSK3beta inhibition by isoliquiritigenin contributes to protecting mitochondria against iron-catalyzed oxidative stress.

  Biochemical pharmacology 20100501

• Lithium modifies brain arachidonic and docosahexaenoic metabolism in rat lipopolysaccharide model of neuroinflammation.

  Journal of lipid research 20100501

• Alteration of cardiac cytochrome P450-mediated arachidonic acid metabolism in response to lipopolysaccharide-induced acute systemic inflammation.

  Pharmacological research 20100501

• Odors activate dual pathways, a TRPC2 and a AA-dependent pathway, in mouse vomeronasal neurons.

  American journal of physiology. Cell physiology 20100501

• Evidence for two conductive pathways in P2X receptor: differences in modulation and selectivity.

  Journal of neurochemistry 20100501

• Upregulation of parathyroid VDR expression by extracellular calcium is mediated by ERK1/2-MAPK signaling pathway.

  American journal of physiology. Renal physiology 20100501

• Epoxyeicosatrienoic acids and endothelium-dependent responses.

  Pflugers Archiv : European journal of physiology 20100501

• The cyclooxygenase site, but not the peroxidase site of cyclooxygenase-2 is required for neurotoxicity in hypoxic and ischemic injury.

  Journal of neurochemistry 20100501

• Vasoconstrictor prostanoids.

  Pflugers Archiv : European journal of physiology 20100501

• Cyclooxygenase-2 and 5-lipoxygenase pathways in diosgenin-induced apoptosis in HT-29 and HCT-116 colon cancer cells.

  International journal of oncology 20100501

• Hepatitis B virus X protein promotes liver cell proliferation via a positive cascade loop involving arachidonic acid metabolism and p-ERK1/2.

  Cell research 20100501

• Dietary arachidonic acid-mediated effects on colon inflammation using transcriptome analysis.

  Molecular nutrition & food research 20100501

• [Blood monocytic L-arginine metabolic changes in diabetic foot syndrome].

  Klinicheskaia laboratornaia diagnostika 20100501

• Supplementation with fatty acids influences the airway nitric oxide and inflammatory markers in patients with cystic fibrosis.

  Journal of pediatric gastroenterology and nutrition 20100501

• RUNX1/core binding factor A2 regulates platelet 12-lipoxygenase gene (ALOX12): studies in human RUNX1 haplodeficiency.

  Blood 20100415

• Glutamate-haem ester bond formation is disfavoured in flavocytochrome P450 BM3: characterization of glutamate substitution mutants at the haem site of P450 BM3.

  The Biochemical journal 20100414

• Design and synthesis of (13S)-methyl-substituted arachidonic acid analogues: templates for novel endocannabinoids.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20100406

• Cytosolic phospholipase a2 activation by Candida albicans in alveolar macrophages: role of dectin-1.

  American journal of respiratory cell and molecular biology 20100401

• The roles of pH in regulation of uterine contraction in the laying hens.

  Animal reproduction science 20100401

• DHA diet reduces AD pathology in young APPswe/PS1 Delta E9 transgenic mice: possible gender effects.

  Journal of neuroscience research 20100401

• Post interventional cardiology urinary thromboxane correlates with PlateletMapping detected aspirin resistance.

  Thrombosis research 20100401

• Modulation of the activity of cytosolic phospholipase A2alpha (cPLA2alpha) by cellular sphingolipids and inhibition of cPLA2alpha by sphingomyelin.

  Journal of lipid research 20100401

• Brain arachidonic acid cascade enzymes are upregulated in a rat model of unilateral Parkinson disease.

  Neurochemical research 20100401

• Platelet activating factor stimulates arachidonic acid release in differentiated keratinocytes via arachidonyl non-selective phospholipase A2.

  Archives of dermatological research 20100401

• Hyperforin induces Ca(2+)-independent arachidonic acid release in human platelets by facilitating cytosolic phospholipase A(2) activation through select phospholipid interactions.

  Biochimica et biophysica acta 20100401

• Safflower and olive oil dietary treatments rescue aberrant embryonic arachidonic acid and nitric oxide metabolism and prevent diabetic embryopathy in rats.

  Molecular human reproduction 20100401

• beta-oxidation modulates metabolic competition between eicosapentaenoic acid and arachidonic acid regulating prostaglandin E(2) synthesis in rat hepatocytes-Kupffer cells.

  Biochimica et biophysica acta 20100401

• Endothelium-derived contracting factors mediate the Ang II-induced endothelial dysfunction in the rat aorta: preventive effect of red wine polyphenols.

  Pflugers Archiv : European journal of physiology 20100401

• Hydroxysteroid (17{beta}) dehydrogenase 12 is essential for mouse organogenesis and embryonic survival.

  Endocrinology 20100401

• Markers of monocyte activation revealed by lipidomic profiling of arachidonic acid-containing phospholipids.

  Journal of immunology (Baltimore, Md. : 1950) 20100401

• Analysis and function of lipid mediators in the nervous system.

  Prostaglandins & other lipid mediators 20100401

• Phospholipase A2 activity of peroxiredoxin 6 promotes invasion and metastasis of lung cancer cells.

  Molecular cancer therapeutics 20100401

• [Association between cytochrome P450 enzymes metabolism and cardiovascular protection].

  Zhonghua xin xue guan bing za zhi 20100401

• Polyunsaturated fatty acid levels of serum and red blood cells in apparently healthy Japanese subjects living in an urban area.

  Journal of atherosclerosis and thrombosis 20100331

• Akt Cys-310-targeted inhibition by hydroxylated benzene derivatives is tightly linked to their immunosuppressive effects.

  The Journal of biological chemistry 20100326

• SDD17 desaturase can convert arachidonic acid to eicosapentaenoic acid in mammalian cells.

  Biochemical and biophysical research communications 20100326

• Physical evidence for substrate binding in preventing cyclooxygenase inactivation under nitrative stress.

  Journal of the American Chemical Society 20100324

• Inhibition of soluble epoxide hydrolase enhances the anti-inflammatory effects of aspirin and 5-lipoxygenase activation protein inhibitor in a murine model.

  Biochemical pharmacology 20100315

• Phospholipase A2 and cyclooxygenase 2 genes influence the risk of interferon-alpha-induced depression by regulating polyunsaturated fatty acids levels.

  Biological psychiatry 20100315

• Serum albumin induces osmotic swelling of rat retinal glial cells.

  Brain research 20100304

• Fenretinide promotes functional recovery and tissue protection after spinal cord contusion injury in mice.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20100303

• In vitro and in vivo anti-inflammatory effects of ethanol extract from Acer tegmentosum.

  Journal of ethnopharmacology 20100302

• Identification of chaulmoogric acid as a small molecule activator of protein phosphatase 5.

  Applied biochemistry and biotechnology 20100301

• Alterations of the endocannabinoid system in an animal model of migraine: evaluation in cerebral areas of rat.

  Cephalalgia : an international journal of headache 20100301

• Brain phospholipid arachidonic acid half-lives are not altered following 15 weeks of N-3 polyunsaturated fatty acid adequate or deprived diet.

  Journal of lipid research 20100301

• Noise exposure alters cyclooxygenase 1 (COX-1) and 5-lipoxygenase (5-LO) expression in the guinea pig cochlea.

  Acta oto-laryngologica 20100301

• Quantitative analysis of phospholipids containing arachidonate and docosahexaenoate chains in microdissected regions of mouse brain.

  Journal of lipid research 20100301

• Effect of gonadectomy on the metabolism of arachidonic acid in isolated kidney of a rat model of metabolic syndrome.

  Metabolism: clinical and experimental 20100301

• Lipid content and fatty acids composition of mature human milk in rural North China.

  The British journal of nutrition 20100301

• Pachymic acid inhibits cell growth and modulates arachidonic acid metabolism in nonsmall cell lung cancer A549 cells.

  Molecular carcinogenesis 20100301

• Suppression of ERK signaling evokes autocrine Fas-mediated death in arachidonic acid-treated human chronic myeloid leukemia K562 cells.

  Journal of cellular physiology 20100301

• Intrarenal cytochrome P-450 metabolites of arachidonic acid in the regulation of the nonclipped kidney function in two-kidney, one-clip Goldblatt hypertensive rats.

  Journal of hypertension 20100301

• The combined impact of plant-derived dietary ingredients and acute stress on the intestinal arachidonic acid cascade in Atlantic salmon (Salmo salar).

  The British journal of nutrition 20100301

• Altered expression of apoptotic factors and synaptic markers in postmortem brain from bipolar disorder patients.

  Neurobiology of disease 20100301

• Effect of arachidonic acid on hypoxia-induced IL-6 production in mouse ES cells: Involvement of MAPKs, NF-kappaB, and HIF-1alpha.

  Journal of cellular physiology 20100301

• Dietary omega-3 polyunsaturated fatty acids suppress expression of EZH2 in breast cancer cells.

  Carcinogenesis 20100301

• Nanomolar vitamin E alpha-tocotrienol inhibits glutamate-induced activation of phospholipase A2 and causes neuroprotection.

  Journal of neurochemistry 20100301

• Nanoparticle inhalation impairs coronary microvascular reactivity via a local reactive oxygen species-dependent mechanism.

  Cardiovascular toxicology 20100301

• A point-of-care assessment of the effects of desmopressin on impaired platelet function using multiple electrode whole-blood aggregometry in patients after cardiac surgery.

  Anesthesia and analgesia 20100301

• Cyclooxygenase-2 and n-6 PUFA are lower and DHA is higher in the cortex of fat-1 mice.

  Neurochemistry international 20100301

• Prothrombinase formation at the site of microvascular injury and aspirin resistance: the effect of simvastatin.

  Thrombosis research 20100301

• Effect of cytochrome P450 polymorphism on arachidonic acid metabolism and their impact on cardiovascular diseases.

  Pharmacology & therapeutics 20100301

• Magnetic resonance molecular imaging of thrombosis in an arachidonic acid mouse model using an activated platelet targeted probe.

  Arteriosclerosis, thrombosis, and vascular biology 20100301

• Brain arachidonic acid uptake and turnover: implications for signaling and bipolar disorder.

  Current opinion in clinical nutrition and metabolic care 20100301

• Cloning and functional expression of an MscL ortholog from Rhizobium etli: characterization of a mechanosensitive channel.

  The Journal of membrane biology 20100301

• Niacin skin flush test: a research tool for studying schizophrenia.

  Psychiatria Danubina 20100301

• The protective effects of paclitaxel on platelet aggregation through the inhibition of thromboxane A2 synthase.

  Archives of pharmacal research 20100301

• Randomized, placebo-controlled trial of flax oil in pediatric bipolar disorder.

  Bipolar disorders 20100301

• [The effect of toxic components in tobacco smoke on the fatty acid profile of dental pulp].

  Georgian medical news 20100301

• In vitro inhibitory activities of Lauraceae aporphine alkaloids.

  Natural product communications 20100301

• Omega-3 fatty acids and inflammatory processes.

  Nutrients 20100301

• The putative lipid raft modulator miltefosine displays immunomodulatory action in T-cell dependent dermal inflammation models.

  European journal of pharmacology 20100225

• Apoptotic cells activate the 'phoenix rising' pathway to promote wound healing and tissue regeneration.

  Science signaling 20100223

• Applicability of the triad concept for the positional specificity of mammalian lipoxygenases.

  The Journal of biological chemistry 20100219

• Arachidonic acid activation of intratumoral steroid synthesis during prostate cancer progression to castration resistance.

  The Prostate 20100215

• Electrostatic tuning of cellular excitability.

  Biophysical journal 20100203

• Plasma and follicular fluid fatty acid profiles in dairy cows.

  Reproduction in domestic animals = Zuchthygiene 20100201

• Cyclic nucleotides inhibit MAP kinase activity in low-dose collagen-stimulated platelets.

  Thrombosis research 20100201

• Zileuton prevents the activation of the leukotriene pathway and reduces sebaceous lipogenesis.

  Experimental dermatology 20100201

• Relationship of omega-3 and omega-6 fatty acids with semen characteristics, and anti-oxidant status of seminal plasma: a comparison between fertile and infertile men.

  Clinical nutrition (Edinburgh, Scotland) 20100201

• Docosahexaenoic acid supplementation fully restores fertility and spermatogenesis in male delta-6 desaturase-null mice.

  Journal of lipid research 20100201

• Hypoxia-induced hyperreactivity of pulmonary arteries: role of cyclooxygenase-2, isoprostanes, and thromboxane receptors.

  Cardiovascular research 20100201

• Brain lipid concentrations in bipolar disorder.

  Journal of psychiatric research 20100201

• Clinical and laboratory phenotype associated with the aspirin-like defect.

  British journal of haematology 20100201

• The function of very long chain polyunsaturated fatty acids in the pineal gland.

  Biochimica et biophysica acta 20100201

• LC-MS/MS analysis of epoxyalcohols and epoxides of arachidonic acid and their oxygenation by recombinant CYP4F8 and CYP4F22.

  Archives of biochemistry and biophysics 20100201

• Protein restriction during pregnancy affects maternal liver lipid metabolism and fetal brain lipid composition in the rat.

  American journal of physiology. Endocrinology and metabolism 20100201

• Oleic acid promotes migration on MDA-MB-231 breast cancer cells through an arachidonic acid-dependent pathway.

  The international journal of biochemistry & cell biology 20100201

• Stimulatory effects of arachidonic acid on myosin ATPase activity and contraction of smooth muscle via myosin motor domain.

  American journal of physiology. Heart and circulatory physiology 20100201

• Protein-protein interaction between cPLA2 and splice variants of alpha-subunit of BK channels.

  American journal of physiology. Cell physiology 20100201

• Increased lipid peroxidation and abnormal fatty acid profiles in seminal and blood plasma of normozoospermic males from infertile couples.

  Human reproduction (Oxford, England) 20100201

• Decrease in uptake of arachidonic acid by indomethacin in LS174T human colon cancer cells; a novel cyclooxygenase-2-inhibition-independent effect.

  Archives of biochemistry and biophysics 20100201

• Simultaneous determination of 2-arachidonoylglycerol, 1-arachidonoylglycerol and arachidonic acid in mouse brain tissue using liquid chromatography/tandem mass spectrometry.

  Journal of mass spectrometry : JMS 20100201

• Prostaglandin-D synthetase induces transcription of the LH beta subunit in the primary culture of chicken anterior pituitary cells via the PPAR signaling pathway.

  Theriogenology 20100201

• L-4F alters hyperlipidemic (but not healthy) mouse plasma to reduce platelet aggregation.

  Arteriosclerosis, thrombosis, and vascular biology 20100201

• Brain-derived neurotrophic factor stimulates production of prostacyclin in cerebral arteries.

  Stroke 20100201

• Molecular cloning and enzymatic characterization of sheep CYP2J.

  Xenobiotica; the fate of foreign compounds in biological systems 20100201

• Rat brain docosahexaenoic acid metabolism is not altered by a 6-day intracerebral ventricular infusion of bacterial lipopolysaccharide.

  Neurochemistry international 20100201

• Altered arachidonic acid metabolism via COX-1 and COX-2 contributes to the endothelial dysfunction of penile arteries from obese Zucker rats.

  British journal of pharmacology 20100201

• The N-terminus of COX-1 and its effect on cyclooxygenase-1 catalytic activity.

  Journal of genetics and genomics = Yi chuan xue bao 20100201

• Influence of omega-6 PUFA arachidonic acid and bone marrow adipocytes on metastatic spread from prostate cancer.

  British journal of cancer 20100119

• Signaling role for lysophosphatidylcholine acyltransferase 3 in receptor-regulated arachidonic acid reacylation reactions in human monocytes.

  Journal of immunology (Baltimore, Md. : 1950) 20100115

• Enhanced production of coenzyme Q10 by overexpressing HMG-CoA reductase and induction with arachidonic acid in Schizosaccharomyces pombe.

  Applied biochemistry and biotechnology 20100101

• Endocannabinoids and cannabinoid analogues block human cardiac Kv4.3 channels in a receptor-independent manner.

  Journal of molecular and cellular cardiology 20100101

• Renal expression of arachidonic acid metabolizing enzymes and RhoA/Rho kinases in fructose insulin resistant hypertensive rats.

  Molecular and cellular biochemistry 20100101

• The total synthesis of 2-O-arachidonoyl-1-O-stearoyl-sn-glycero-3-phosphocholine-1,3,1'-(13)C3 and -2,1'-(13)C2 by a novel chemoenzymatic method.

  Chemistry and physics of lipids 20100101

• Supplementation of DHA but not DHA with arachidonic acid during pregnancy and lactation influences general movement quality in 12-week-old term infants.

  The British journal of nutrition 20100101

• Inhibition of carboxylesterase activity of THP1 monocytes/macrophages and recombinant human carboxylesterase 1 by oxysterols and fatty acids.

  Biochimica et biophysica acta 20100101

• Acute doxorubicin cardiotoxicity alters cardiac cytochrome P450 expression and arachidonic acid metabolism in rats.

  Toxicology and applied pharmacology 20100101

• Oxidative mechanisms of IL-4-induced IL-6 expression in vascular endothelium.

  Cytokine 20100101

• Inhibition of soluble epoxide hydrolase by trans-4- [4-(3-adamantan-1-yl-ureido)-cyclohexyloxy]-benzoic acid is protective against ischemia-reperfusion injury.

  Journal of cardiovascular pharmacology 20100101

• Human plasma concentrations of malondialdehyde (MDA) and the F2-isoprostane 15(S)-8-iso-PGF(2alpha) may be markedly compromised by hemolysis: evidence by GC-MS/MS and potential analytical and biological ramifications.

  Clinical biochemistry 20100101

• Glucose enhances expression of TRPC1 and calcium entry in endothelial cells.

  American journal of physiology. Heart and circulatory physiology 20100101

• Aspirin, arachidonic acid and the regulation of mood.

  Prostaglandins, leukotrienes, and essential fatty acids 20100101

• Phospholipase A2-derived lysophosphatidylcholine triggers Ca2+ entry in dystrophic skeletal muscle fibers.

  Biochemical and biophysical research communications 20100101

• Arachidonic acid release mediated by OX1 orexin receptors.

  British journal of pharmacology 20100101

• Arachidonic acid stimulates extracellular Ca(2+) entry in rat pancreatic beta cells via activation of the noncapacitative arachidonate-regulated Ca(2+) (ARC) channels.

  Cell calcium 20100101

• Negative regulation of Ca(2+) influx during P2Y(2) purinergic receptor activation is mediated by Gbetagamma-subunits.

  Cell calcium 20100101

• A rapid method for determining arachidonic:eicosapentaenoic acid ratios in whole blood lipids: correlation with erythrocyte membrane ratios and validation in a large Italian population of various ages and pathologies.

  Lipids in health and disease 20100101

• The very low density lipoprotein receptor is not necessary for maintaining brain polyunsaturated fatty acid concentrations.

  Prostaglandins, leukotrienes, and essential fatty acids 20100101

• Cloning, purification and characterization of non-human primate 12/15-lipoxygenases.

  Prostaglandins, leukotrienes, and essential fatty acids 20100101

• Ceramide and ceramide 1-phosphate in health and disease.

  Lipids in health and disease 20100101

• Differential impact of familial hypercholesterolemia and combined hyperlipidemia on vascular wall and network remodeling in mice.

  Microcirculation (New York, N.Y. : 1994) 20100101

• Evaluation of antiplatelet effects of a modified protocol by platelet aggregation in patients undergoing 'one-stop' hybrid coronary revascularization.

  Platelets 20100101

• A prostacyclin analogue, iloprost, protects from bleomycin-induced pulmonary fibrosis in mice.

  Respiratory research 20100101

• Platelet hyporesponsiveness to acetylsalicylic acid can be transferred by plasma in humans.

  Pharmacology 20100101

• Platelet function and Isoprostane biology. Should isoprostanes be the newest member of the orphan-ligand family?

  Journal of biomedical science 20100101

• Effect of obesity on platelet reactivity and response to low-dose aspirin.

  Preventive cardiology 20100101

• Individual variation and intraclass correlation in arachidonic acid and eicosapentaenoic acid in chicken muscle.

  Lipids in health and disease 20100101

• Cytosolic phospholipase A2alpha mediates Pseudomonas aeruginosa LPS-induced airway constriction of CFTR -/- mice.

  Respiratory research 20100101

• The effect of menstrual cycle on platelet aggregation in reproductive-age women.

  Platelets 20100101

• Validation of a procedure to assess ASA-response in patients with decreased, initial TRAP induced aggregation.

  Platelets 20100101

• Effects of the omega-6:omega-3 fatty acid ratio of fat emulsions on the fatty acid composition in cell membranes and the anti-inflammatory action.

  JPEN. Journal of parenteral and enteral nutrition 20100101

• Vegetarian diets are associated with healthy mood states: a cross-sectional study in seventh day adventist adults.

  Nutrition journal 20100101

• Role of leukotriene B4 in 5-lipoxygenase metabolite- and allergy-induced itch-associated responses in mice.

  Biological & pharmaceutical bulletin 20100101

• Platelet aggregation responses vary over a period of time in healthy controls.

  Platelets 20100101

• Human monocyte differentiation stage affects response to arachidonic acid.

  Cellular immunology 20100101

• [The role of prostaglandins in platelet aggregation in metabolic syndrome].

  Vestnik Rossiiskoi akademii meditsinskikh nauk 20100101

• Red blood cells (RBCs), epoxyeicosatrienoic acids (EETs) and adenosine triphosphate (ATP).

  Pharmacological reports : PR 20100101

• Transcellular biosynthesis of eicosanoids.

  Pharmacological reports : PR 20100101

• Cytochrome P450-dependent metabolism of omega-6 and omega-3 long-chain polyunsaturated fatty acids.

  Pharmacological reports : PR 20100101

• Identification of 4-[4-(4-fluoro-phenyl)-thiazol-2-ylamino]-2,6-dimethyl-phenol (KR-33749) as an inhibitor of 5-lipoxygenase with potent antiinflammatory activity.

  Pharmacology 20100101

• Study of inhibitors of the PGH synthases for which potency is regulated by the redox state of the enzymes.

  Methods in molecular biology (Clifton, N.J.) 20100101

• In vitro cyclooxygenase activity assay in tissue homogenates.

  Methods in molecular biology (Clifton, N.J.) 20100101

• [The role of modification of fatty acid composition of erythrocyte lipids in pathogenesis of arterial hypertension].

  Kardiologiia 20100101

• Thromboxane synthase inhibitors and thromboxane A2 receptor antagonists: a quantitative structure activity relationships (QSARs) analysis.

  Current medicinal chemistry 20100101

• Does pioglitazone directly influence platelet aggregation?

  Cardiology 20100101

• Effect of pioglitazone on platelet aggregation in a healthy cohort.

  Cardiology 20100101

• [Changes in lipid composition of human plasma and erythrocyte membranes due to sodium hydroxybutyrate and normobaric hyperoxia during bed rest].

  Aviakosmicheskaia i ekologicheskaia meditsina = Aerospace and environmental medicine 20100101

• [Modulation of platelet tyrosine phosphatases by arachidonic acid metabolites in diabetes mellitus complicated with acute pyogenic inflammation].

  Patologicheskaia fiziologiia i eksperimental'naia terapiia 20100101

• The N-terminal domain of Orai3 determines selectivity for activation of the store-independent ARC channel by arachidonic acid.

  Channels (Austin, Tex.) 20100101

• Selenoprotein P protects cells from lipid hydroperoxides generated by 15-LOX-1.

  Prostaglandins, leukotrienes, and essential fatty acids 20100101

• Effect of oxidized arachidonic acid and hexanal on the mouse taste perception of bitterness and umami.

  Bioscience, biotechnology, and biochemistry 20100101

• Applying internal coordinate mechanics to model the interactions between 8R-lipoxygenase and its substrate.

  BMC bioinformatics 20100101

• Neutrophil unsaturated fatty acid release by GM-CSF is impaired in cystic fibrosis.

  Lipids in health and disease 20100101

• Blood arachidonic acid and HDL cholesterol influence the phagocytic abilities of human monocytes/macrophages.

  Annals of nutrition & metabolism 20100101

• Vascular pharmacology of epoxyeicosatrienoic acids.

  Advances in pharmacology (San Diego, Calif.) 20100101

• Functional interaction between acyl-CoA synthetase 4, lipooxygenases and cyclooxygenase-2 in the aggressive phenotype of breast cancer cells.

  PloS one 20100101

• Metabolic footprint of diabetes: a multiplatform metabolomics study in an epidemiological setting.

  PloS one 20100101

• Cytosolic phospholipase A₂ inhibition is involved in the protective effect of nortriptyline in primary astrocyte cultures exposed to combined oxygen-glucose deprivation.

  Pharmacological reports : PR 20100101

• Antinociceptive activity of atranorin in mice orofacial nociception tests.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20100101

• Interaction of arachidonic acid with electrogenic properties of mouse chemosensory neurons.

  European journal of medical research 20100101

• Cardiovascular effects of low-dose aspirin, traditional non-steroidal anti-inflammatory drugs and coxibs.

  Bulletin et memoires de l'Academie royale de medecine de Belgique 20100101

• Plasma metabolomic profiles reflective of glucose homeostasis in non-diabetic and type 2 diabetic obese African-American women.

  PloS one 20100101

• Comparison of anti-inflammatory and anti-nociceptive activities of Curcuma wenyujin Y.H. Chen et C. Ling and Scutellaria baicalensis Georgi.

  African journal of traditional, complementary, and alternative medicines : AJTCAM 20100101

• Functional modulation of mitochondria by eicosapentaenoic acid provides protection against ceramide toxicity to C6 glioma cells.

  Journal of agricultural and food chemistry 20091223

• Arachidonic acid induces Fas and FasL upregulation in human leukemia U937 cells via Ca2+/ROS-mediated suppression of ERK/c-Fos pathway and activation of p38 MAPK/ATF-2 pathway.

  Toxicology letters 20091215

• Chain reactions: early-life stress alters the metabolic profile of plasma polyunsaturated fatty acids in adulthood.

  Behavioural brain research 20091214

• Coactosin-like protein functions as a stabilizing chaperone for 5-lipoxygenase: role of tryptophan 102.

  The Biochemical journal 20091214

• Development of enzyme-linked immunosorbent assay for 8-iso-prostaglandin F2alpha, a biomarker of oxidative stress in vivo, and its application to the quantification in aged rats.

  Journal of pharmaceutical and biomedical analysis 20091205

• Extracellular release of ATP mediated by cyclic mechanical stress leads to mobilization of AA in trabecular meshwork cells.

  Investigative ophthalmology & visual science 20091201

• The formation of monocyte-platelet aggregates is independent of on-treatment residual agonists'-inducible platelet reactivity.

  Atherosclerosis 20091201

• Spectroelectrochemical characterization of pain biomarkers.

  Analytical biochemistry 20091201

• In retinal vein occlusion platelet response to thrombin is increased.

  Thrombosis research 20091201

• Control of free arachidonic acid levels by phospholipases A2 and lysophospholipid acyltransferases.

  Biochimica et biophysica acta 20091201

• Loss of heart phospholipid arachidonic acid without phospholipid peroxidation in anaesthetized rats rewarmed after prolonged deep hypothermia.

  Cryobiology 20091201

• Both B1R and B2R act as intermediate signaling molecules in high glucose-induced stimulation of glutamate uptake in ARPE cells.

  Journal of cellular physiology 20091201

• Differential effects of arachidonic and eicosapentaenoic Acid-derived eicosanoids on polymorphonuclear transmigration across endothelial cell cultures.

  The Journal of pharmacology and experimental therapeutics 20091201

• Localization of the succinate receptor in the distal nephron and its signaling in polarized MDCK cells.

  Kidney international 20091201

• EDHF function in the ductus arteriosus: evidence against involvement of epoxyeicosatrienoic acids and 12S-hydroxyeicosatetraenoic acid.

  American journal of physiology. Heart and circulatory physiology 20091201

• Anti-inflammatory action of arachidonoyl lysophosphatidylcholine or 15-hydroperoxy derivative in zymosan A-induced peritonitis.

  Prostaglandins & other lipid mediators 20091201

• Comparison of the relative activities of inducing platelet apoptosis stimulated by various platelet-activating agents.

  Platelets 20091201

• Arachidonic acid induces acetyl-CoA carboxylase 1 expression via activation of CREB1.

  Endocrine 20091201

• Engineering of a novel hybrid enzyme: an anti-inflammatory drug target with triple catalytic activities directly converting arachidonic acid into the inflammatory prostaglandin E2.

  Protein engineering, design & selection : PEDS 20091201

• Long-chain polyunsaturated fatty acids stimulate cellular fatty acid uptake in human placental choriocarcinoma (BeWo) cells.

  Placenta 20091201

• 3-methylcholanthrene and benzo(a)pyrene modulate cardiac cytochrome P450 gene expression and arachidonic acid metabolism in male Sprague Dawley rats.

  British journal of pharmacology 20091201

• Rapid, simultaneous quantitation of mono and dioxygenated metabolites of arachidonic acid in human CSF and rat brain.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20091201

• Characterization of TWIK-2, a two-pore domain K+ channel, cloned from the rat middle cerebral artery.

  Experimental biology and medicine (Maywood, N.J.) 20091201

• The plasma lipidomic signature of nonalcoholic steatohepatitis.

  Hepatology (Baltimore, Md.) 20091201

• Antiplatelets and stroke outcomes: state of the science.

  Critical care nursing clinics of North America 20091201

• Prostaglandin F(2alpha) receptor signaling facilitates bleomycin-induced pulmonary fibrosis independently of transforming growth factor-beta.

  Nature medicine 20091201

• DNA methylation, induced by beta-carotene and arachidonic acid, plays a regulatory role in the pro-angiogenic VEGF-receptor (KDR) gene expression in endothelial cells.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20091201

• Increased growth inhibitory effects on human cancer cells and anti-inflammatory potency of shogaols from Zingiber officinale relative to gingerols.

  Journal of agricultural and food chemistry 20091125

• Arachidonic acid: a key molecule for astrocyte survival to peroxynitrite.

  Glia 20091115

• Identification of 13-hydroxy-14,15-epoxyeicosatrienoic acid as an acid-stable endothelium-derived hyperpolarizing factor in rabbit arteries.

  The Journal of biological chemistry 20091106

• Hypersusceptibility of neutrophil granulocytes towards lethal action of free fatty acids contained in enzyme-modified atherogenic low density lipoprotein.

  Atherosclerosis 20091101

• Regulation of prostaglandin synthesis in ovaries of sexually-mature zebrafish (Danio rerio).

  Molecular reproduction and development 20091101

• The arachidonic acid effect on platelet nitric oxide level.

  Biochimica et biophysica acta 20091101

• In vitro synthesis of arachidonoyl amino acids by cytochrome c.

  Prostaglandins & other lipid mediators 20091101

• The C type natriuretic peptide receptor tethers AHNAK1 at the plasma membrane to potentiate arachidonic acid-induced calcium mobilization.

  American journal of physiology. Cell physiology 20091101

• Deletion of GPR40 impairs glucose-induced insulin secretion in vivo in mice without affecting intracellular fuel metabolism in islets.

  Diabetes 20091101

• Steroids mediate resistance to the bactericidal effect of phosphatidylcholines against Helicobacter pylori.

  FEMS microbiology letters 20091101

• Single cell oil production by Mortierella alpina.

  Journal of biotechnology 20091012

• Study of the mechanism of antihypertensive peptides VPP and IPP in spontaneously hypertensive rats by DNA microarray analysis.

  European journal of pharmacology 20091012

• A role for AMPK in the inhibition of glucose-6-phosphate dehydrogenase by polyunsaturated fatty acids.

  Biochemical and biophysical research communications 20091009

• TLR-4 mediated group IVA phospholipase A(2) activation is phosphatidic acid phosphohydrolase 1 and protein kinase C dependent.

  Biochimica et biophysica acta 20091001

• Neutrophil generation of inflammatory precursors is not modulated by docosahexaenoic acid.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20091001

• Antithrombotic and antiplatelet activities of fenofibrate, a lipid-lowering drug.

  Atherosclerosis 20091001

• Asian sand dust aggravates allergic rhinitis in guinea pigs induced by Japanese cedar pollen.

  Inhalation toxicology 20091001

• Bipolar disorder and mechanisms of action of mood stabilizers.

  Brain research reviews 20091001

• The biosynthesis of N-arachidonoyl dopamine (NADA), a putative endocannabinoid and endovanilloid, via conjugation of arachidonic acid with dopamine.

  Prostaglandins, leukotrienes, and essential fatty acids 20091001

• 90-Day feeding and genotoxicity studies on a refined arachidonic acid-rich oil.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20091001

• A 4-oxo-2(E)-nonenal-derived glutathione adduct from 15-lipoxygenase-1-mediated oxidation of cytosolic and esterified arachidonic acid.

  Free radical biology & medicine 20091001

• Efficacy of sauchinone as a novel AMPK-activating lignan for preventing iron-induced oxidative stress and liver injury.

  Free radical biology & medicine 20091001

• Resveratrol protects mitochondria against oxidative stress through AMP-activated protein kinase-mediated glycogen synthase kinase-3beta inhibition downstream of poly(ADP-ribose)polymerase-LKB1 pathway.

  Molecular pharmacology 20091001

• CYP-omega-hydroxylation-dependent metabolites of arachidonic acid inhibit the basolateral 10 pS chloride channel in the rat thick ascending limb.

  Kidney international 20091001

• Multiple action agents and the eye: do they really stabilize mast cells?

  Current opinion in allergy and clinical immunology 20091001

• Pitfalls in the use of arachidonic acid oxidation products to assign lipoxygenase activity in cancer cells.

  Free radical research 20091001

• Toponomics analysis of drug-induced changes in arachidonic acid-dependent signaling pathways during spinal nociceptive processing.

  Journal of proteome research 20091001

• Is the brain arachidonic acid cascade a common target of drugs used to manage bipolar disorder?

  Biochemical Society transactions 20091001

• Involvement of constitutive nitric oxide synthase in ghrelin-induced cytosolic phospholipase A(2) activation in gastric mucosal cell protection against ethanol cytotoxicity.

  Inflammopharmacology 20091001

• Peroxisome proliferators attenuate free arachidonic acid pool in the kidney through inducing lysophospholipid acyltransferases.

  Journal of pharmacological sciences 20091001

• Enhanced lumbar spine bone mineral content in piglets fed arachidonic acid and docosahexaenoic acid is modulated by severity of growth restriction.

  The British journal of nutrition 20091001

• Down-regulation of 20-HETE synthesis and signaling inhibits renal adenocarcinoma cell proliferation and tumor growth.

  Anticancer research 20091001

• Evidence for the association of peroxidases with the antioxidant effect of p-coumaric acid in endothelial cells exposed to high glucose plus arachidonic acid.

  BMB reports 20090930

• Kinetic and structural investigations of the allosteric site in human epithelial 15-lipoxygenase-2.

  Biochemistry 20090915

• Substrate specificity effects of lipoxygenase products and inhibitors on soybean lipoxygenase-1.

  Bioorganic & medicinal chemistry 20090915

• Biology of endocannabinoid synthesis system.

  Prostaglandins & other lipid mediators 20090901

• Regulation of arachidonate remodeling enzymes impacts eosinophil survival during allergic asthma.

  American journal of respiratory cell and molecular biology 20090901

• Evaluation of the platelet count drop method for assessment of platelet function in comparison with 'gold standard' light transmission aggregometry.

  Thrombosis research 20090901

• Identification of a novel fatty acid elongase with a wide substrate specificity from arachidonic acid-producing fungus Mortierella alpina 1S-4.

  Applied microbiology and biotechnology 20090901

• The arachidonic acid epoxygenase is a component of the signaling mechanisms responsible for VEGF-stimulated angiogenesis.

  Archives of biochemistry and biophysics 20090901

• Characterization of novel radicals from COX-catalyzed arachidonic acid peroxidation.

  Free radical biology & medicine 20090901

• The cardioprotective effects of fish oil during pressure overload are blocked by high fat intake: role of cardiac phospholipid remodeling.

  Hypertension (Dallas, Tex. : 1979) 20090901

• The molecular architecture of the arachidonate-regulated Ca2+-selective ARC channel is a pentameric assembly of Orai1 and Orai3 subunits.

  The Journal of physiology 20090901

• The mechanism and mitigation of niacin-induced flushing.

  International journal of clinical practice 20090901

• [Novel type of antimicrobial mechanism in host macrophages against mycobacterial infections].

  Nihon Hansenbyo Gakkai zasshi = Japanese journal of leprosy : official organ of the Japanese Leprosy Association 20090901

• Effects of clopidogrel on 'aspirin specific' pathways of platelet inhibition.

  Platelets 20090901

• Platelet antiaggregating activity of ginsenosides isolated from processed ginseng.

  Die Pharmazie 20090901

• Dietary supplementation with arachidonic acid but not eicosapentaenoic or docosahexaenoic acids alter lipids metabolism in C57BL/6J mice.

  General physiology and biophysics 20090901

• Arachidonic acid-induced apoptosis of human neuroblastoma SK-N-SH cells is mediated through mitochondrial alteration elicited by ROS and Ca(2+)-evoked activation of p38alpha MAPK and JNK1.

  Toxicology 20090821

• Differential sensitivity and mechanism of inhibition of COX-2 oxygenation of arachidonic acid and 2-arachidonoylglycerol by ibuprofen and mefenamic acid.

  Biochemistry 20090811

• Early life programming of immune and lung function: can we now exclude a role of arachidonic acid exposure?

  The British journal of nutrition 20090801

• Prenatal arachidonic acid exposure and selected immune-related variables in childhood.

  The British journal of nutrition 20090801

• Fatty acid pattern in serum is associated with bone mineralisation in healthy 8-year-old children.

  The British journal of nutrition 20090801

• Native platelet aggregation and response to aspirin in persons with the metabolic syndrome and its components.

  Metabolic syndrome and related disorders 20090801

• Glutathione disulfide induces neural cell death via a 12-lipoxygenase pathway.

  Cell death and differentiation 20090801

• TLR2 ligands augment cPLA2alpha activity and lead to enhanced leukotriene release in human monocytes.

  Journal of leukocyte biology 20090801

• C-reactive protein impairs coronary arteriolar dilation to prostacyclin synthase activation: role of peroxynitrite.

  Journal of molecular and cellular cardiology 20090801

• Quinacrine protects neuronal cells against heat-induced injury.

  Cell biology international 20090801

• Methods for imaging and detecting modification of proteins by reactive lipid species.

  Free radical biology & medicine 20090801

• Activation of phospholipase A2 is involved in indomethacin-induced damage in Caco-2 cells.

  Toxicology in vitro : an international journal published in association with BIBRA 20090801

• Can we prevent diabetic birth defects with micronutrients?

  Diabetes, obesity & metabolism 20090801

• Associations between term birth dimensions and prenatal exposure to essential and trans fatty acids.

  Early human development 20090801

• A high omega-3 fatty acid diet reduces retinal lesions in a murine model of macular degeneration.

  The American journal of pathology 20090801

• Interactions of gallic acid, resveratrol, quercetin and aspirin at the platelet cyclooxygenase-1 level. Functional and modelling studies.

  Thrombosis and haemostasis 20090801

• Cross validation of the Multiple Electrode Aggregometry. A prospective trial in healthy volunteers.

  Thrombosis and haemostasis 20090801

• In vitro fatty acid enrichment of macrophages alters inflammatory response and net cholesterol accumulation.

  The British journal of nutrition 20090801

• Predictive value of post-treatment platelet reactivity for occurrence of post-discharge bleeding after non-ST elevation acute coronary syndrome. Shifting from antiplatelet resistance to bleeding risk assessment?

  EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090801

• Arachidonic acid stimulates cell adhesion through a novel p38 MAPK-RhoA signaling pathway that involves heat shock protein 27.

  The Journal of biological chemistry 20090731

• Dual 12/15- and 5-lipoxygenase deficiency in macrophages alters arachidonic acid metabolism and attenuates peritonitis and atherosclerosis in ApoE knock-out mice.

  The Journal of biological chemistry 20090731

• Anti-inflammatory effects of ethanolic extract and alkamides-derived from Heliopsis longipes roots.

  Journal of ethnopharmacology 20090730

• EDHF: an update.

  Clinical science (London, England : 1979) 20090716

• Lipoxygenase-mediated pro-radical effect of melatonin via stimulation of arachidonic acid metabolism.

  Toxicology and applied pharmacology 20090715

• Anti-inflammatory potential of 2-styrylchromones regarding their interference with arachidonic acid metabolic pathways.

  Biochemical pharmacology 20090715

• Mechanistic investigations of human reticulocyte 15- and platelet 12-lipoxygenases with arachidonic acid.

  Biochemistry 20090707

• Cystic fibrosis fatty acid imbalance is linked to ceramide deficiency and corrected by fenretinide.

  American journal of respiratory cell and molecular biology 20090701

• Vitamin K prevents oxidative cell death by inhibiting activation of 12-lipoxygenase in developing oligodendrocytes.

  Journal of neuroscience research 20090701

• (Endo)cannabinoids mediate different Ca2+ entry mechanisms in human bronchial epithelial cells.

  Naunyn-Schmiedeberg's archives of pharmacology 20090701

• Phospholipase A2-activating protein (PLAA) enhances cisplatin-induced apoptosis in HeLa cells.

  Cellular signalling 20090701

• Improvement of arachidonic acid and eicosapentaenoic acid production by increasing the copy number of the genes encoding fatty acid desaturase and elongase into Pichia pastoris.

  Biotechnology letters 20090701

• Arachidonic acid potentiates hypoxia-induced VEGF expression in mouse embryonic stem cells: involvement of Notch, Wnt, and HIF-1alpha.

  American journal of physiology. Cell physiology 20090701

• Characterization of the binding of drugs to human intestinal fatty acid binding protein (IFABP): potential role of IFABP as an alternative to albumin for in vitro-in vivo extrapolation of drug kinetic parameters.

  Drug metabolism and disposition: the biological fate of chemicals 20090701

• Abscisic acid negatively regulates elicitor-induced synthesis of capsidiol in wild tobacco.

  Plant physiology 20090701

• Evidence for the presence of prostaglandin H synthase like enzyme in female Setaria cervi and its inhibition by diethylcarbamazine.

  Acta tropica 20090701

• Inhibition of astroglial glutamate transport by polyunsaturated fatty acids: evidence for a signalling role of docosahexaenoic acid.

  Neurochemistry international 20090701

• Identification of the large-conductance background K+ channel in mouse B cells as TREK-2.

  American journal of physiology. Cell physiology 20090701

• 2-Oxoamide inhibitors of phospholipase A2 activity and cellular arachidonate release based on dipeptides and pseudodipeptides.

  Bioorganic & medicinal chemistry 20090701

• Involvement of multiple protein kinases in cPLA2 phosphorylation, arachidonic acid release, and cell death in in vivo and in vitro models of 1-methyl-4-phenylpyridinium-induced parkinsonism--the possible key role of PKG.

  Journal of neurochemistry 20090701

• Benzhydrylquinazolinediones: novel cytosolic phospholipase A2alpha inhibitors with improved physicochemical properties.

  Bioorganic & medicinal chemistry 20090701

• Calcium-independent phospholipase A2 participates in KCl-induced calcium sensitization of vascular smooth muscle.

  Cell calcium 20090701

• Free fatty acid profiles in preeclampsia.

  Prostaglandins, leukotrienes, and essential fatty acids 20090701

• Spice active principles as the inhibitors of human platelet aggregation and thromboxane biosynthesis.

  Prostaglandins, leukotrienes, and essential fatty acids 20090701

• Comparison of fatty acid contents of erythrocyte membrane in hemodialysis and peritoneal dialysis patients.

  Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 20090701

• Pyrrolidine dithiocarbamate reduces vascular prostanoid-induced responses in aged type 2 diabetic rat model.

  Journal of pharmacological sciences 20090701

• Docosahexaenoic acid and eicosapentaenoic acid affect ovarian prostaglandin levels differently in rats.

  Nutrition research (New York, N.Y.) 20090701

• Ethnic differences in early pregnancy maternal n-3 and n-6 fatty acid concentrations: an explorative analysis.

  The British journal of nutrition 20090601

• FGF-activated calcium channels control neural gene expression in Xenopus.

  Biochimica et biophysica acta 20090601

• Imaging elevated brain arachidonic acid signaling in unanesthetized serotonin transporter (5-HTT)-deficient mice.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20090601

• Cytotoxicity induced by inhibition of thioredoxin reductases via multiple signaling pathways: role of cytosolic phospholipase A(2)alpha-dependent and -independent release of arachidonic acid.

  Journal of cellular physiology 20090601

• Physalin B inhibits Rhodnius prolixus hemocyte phagocytosis and microaggregation by the activation of endogenous PAF-acetyl hydrolase activities.

  Journal of insect physiology 20090601

• Inhibition of arachidonic acid metabolism and its implication on cell proliferation and tumour-angiogenesis.

  International immunopharmacology 20090601

• Arachidonic acid, ARC channels, and Orai proteins.

  Cell calcium 20090601

• Oxidized metabolites of oltipraz exert cytoprotective effects against arachidonic acid through AMP-activated protein kinase-dependent cellular antioxidant effect and mitochondrial protection.

  Drug metabolism and disposition: the biological fate of chemicals 20090601

• Cyclooxygenase-2 induced by zymosan in human monocyte-derived dendritic cells shows high stability, and its expression is enhanced by atorvastatin.

  The Journal of pharmacology and experimental therapeutics 20090601

• TRPC channel lipid specificity and mechanisms of lipid regulation.

  Cell calcium 20090601

• Low molecular weight heparin significantly reduces embolisation after carotid endarterectomy--a randomised controlled trial.

  European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 20090601

• Stress-induced activation of Nox contributes to cell survival signalling via production of hydrogen peroxide.

  Journal of neurochemistry 20090601

• PKC and PLA2: probing the complexities of the calcium network.

  Cell calcium 20090601

• Role of hydrogen peroxide and the impact of glutathione peroxidase-1 in regulation of cerebral vascular tone.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20090601

• Acute but not chronic donepezil increases muscarinic receptor-mediated signaling via arachidonic acid in unanesthetized rats.

  Journal of Alzheimer's disease : JAD 20090601

• The role of alpha1-adrenoceptor and arachidonate pathways in increased tone of demucosalized bladder tissue.

  The Journal of urology 20090601

• Integration of skeletal muscle resistance arteriolar reactivity for perfusion responses in the metabolic syndrome.

  American journal of physiology. Regulatory, integrative and comparative physiology 20090601

• Lipids in Ca2+ signalling--an introduction.

  Cell calcium 20090601

• Regulation of voltage-gated Ca2+ channels by lipids.

  Cell calcium 20090601

• Arachidonic acid enhances intracellular calcium levels in dentate gyrus, but not CA1, in aged rat.

  Neuroscience research 20090601

• Peroxide-induced radical formation at TYR385 and TYR504 in human PGHS-1.

  Journal of inorganic biochemistry 20090601

• Platelets arachidonic acid metabolism in patients with essential hypertension.

  Platelets 20090601

• A complex between 6-iodolactone and the peroxisome proliferator-activated receptor type gamma may mediate the antineoplastic effect of iodine in mammary cancer.

  Prostaglandins & other lipid mediators 20090601

• Phaselicystis flava gen. nov., sp. nov., an arachidonic acid-containing soil myxobacterium, and the description of Phaselicystidaceae fam. nov.

  International journal of systematic and evolutionary microbiology 20090601

• Adrenal glands and testes as steroidogenic tissue are affected by retinoylation reaction.

  Journal of bioenergetics and biomembranes 20090601

• Role of epidermal growth factor receptor transactivation in the activation of cytosolic phospholipase A(2) in leptin protection of salivary gland acinar cells against ethanol cytotoxicity.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20090601

• New insights on the possible role of mast cells in aspirin-induced asthma.

  Current molecular pharmacology 20090601

• Mood-stabilizers target the brain arachidonic acid cascade.

  Current molecular pharmacology 20090601

• Apolipoprotein D modulates F2-isoprostane and 7-ketocholesterol formation and has a neuroprotective effect on organotypic hippocampal cultures after kainate-induced excitotoxic injury.

  Neuroscience letters 20090522

• Chagasic antibodies induce cardiac COX-2/iNOS mRNA expression with PGE2/NO production.

  International journal of cardiology 20090515

• Modulation of Delta9-tetrahydrocannabinol-induced MCF-7 breast cancer cell growth by cyclooxygenase and aromatase.

  Toxicology 20090502

• Molecules in focus: cytosolic phospholipase A2-alpha.

  The international journal of biochemistry & cell biology 20090501

• Arachidonic acid prevents fatty liver induced by conjugated linoleic acid in mice.

  The British journal of nutrition 20090501

• A new method for the study of essential fatty acid requirements in fish larvae.

  The British journal of nutrition 20090501

• Effect of increased aspirin dose after stenting in association with ClOpidogrel: the FIASCO randomized study.

  Thrombosis research 20090501

• The regulation of NADPH oxidase and its association with cell proliferation in human lens epithelial cells.

  Investigative ophthalmology & visual science 20090501

• Inhibitory effects of polyunsaturated fatty acids on Kv4/KChIP potassium channels.

  American journal of physiology. Cell physiology 20090501

• Cyclooxygenase-2 in mucosal DC mediates induction of regulatory T cells in the intestine through suppression of IL-4.

  Mucosal immunology 20090501

• The effect of milrinone on platelet activation as determined by TEG platelet mapping.

  Anesthesia and analgesia 20090501

• Identification of 5-lipoxygenase and microsomal prostaglandin E2 synthase-1 as functional targets of the anti-inflammatory and anti-carcinogenic garcinol.

  Biochemical pharmacology 20090501

• The impact of intravenous aspirin administration on platelet aspirin resistance after on-pump coronary artery bypass surgery.

  Platelets 20090501

• Cross validation of aspirin effect in healthy individuals by Impact-R and PFA-100: a double blind randomized placebo controlled trial.

  Platelets 20090501

• Differences in responses of platelets to fluid shear stress in patients with peripheral artery disease (PAD) and coronary artery disease (CAD).

  Platelets 20090501

• Arachidonic acid potently inhibits both postsynaptic-type Kv4.2 and presynaptic-type Kv1.4 IA potassium channels.

  The European journal of neuroscience 20090501

• [Production of functional lipids by microorganisms: arachidonic acid and related polyunsaturated fatty acids].

  Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 20090501

• Relationship between long-chain polyunsaturated fatty acids at birth and motor function at 7 years of age.

  European journal of clinical nutrition 20090401

• Isoprostanes.

  Journal of lipid research 20090401

• Chemical synthesis, pharmacological characterization, and possible formation in unicellular fungi of 3-hydroxy-anandamide.

  Journal of lipid research 20090401

• HDL is the major lipoprotein carrier of plasma F2-isoprostanes.

  Journal of lipid research 20090401

• Bacterial lipopolysaccharide induces an endocrine switch from prostaglandin F2alpha to prostaglandin E2 in bovine endometrium.

  Endocrinology 20090401

• Modulation of muscle rNaV1.4 Na+ channel isoform by arachidonic acid and its non-metabolized analog.

  Journal of cellular physiology 20090401

• Up-regulation of microsomal prostaglandin E synthase-1 in COX-1 and COX-2 knock-out mouse fibroblast cell lines.

  Prostaglandins & other lipid mediators 20090401

• Diagnostic utility of light transmission platelet aggregometry: results from a prospective study of individuals referred for bleeding disorder assessments.

  Journal of thrombosis and haemostasis : JTH 20090401

• Substrate selectivity of 5-hydroxyeicosanoid dehydrogenase and its inhibition by 5-hydroxy-Delta6-long-chain fatty acids.

  The Journal of pharmacology and experimental therapeutics 20090401

• Arachidonic acid release by H2O2 mediated proliferation of mouse embryonic stem cells: involvement of Ca2+/PKC and MAPKs-induced EGFR transactivation.

  Journal of cellular biochemistry 20090401

• Differential involvement of COX1 and COX2 in the vasculopathy associated with the alpha-galactosidase A-knockout mouse.

  American journal of physiology. Heart and circulatory physiology 20090401

• Role of systemic and local administration of selective inhibitors of cyclo-oxygenase 1 and 2 in an experimental model of periodontal disease in rats.

  Journal of periodontal research 20090401

• Free Fatty Acids and Methyl Jasmonate Trigger Defense Reactions in Laminaria digitata.

  Plant & cell physiology 20090401

• Arachidonic acid metabolites follow the preferential course of cyclooxygenase pathway for the basal tone in the internal anal sphincter.

  American journal of physiology. Gastrointestinal and liver physiology 20090401

• The influence of acetylshikonin, a natural naphthoquinone, on the production of leukotriene B4 and thromboxane A2 in rat neutrophils.

  European journal of pharmacology 20090401

• Dopamine (DA) induced irreversible proteasome inhibition via DA derived quinones.

  Free radical research 20090401

• Direct effect of ropivacaine involves lipoxygenase pathway activation in rat aortic smooth muscle.

  Canadian journal of anaesthesia = Journal canadien d'anesthesie 20090401

• Phycocyanin liposomes for topical anti-inflammatory activity: in-vitro in-vivo studies.

  The Journal of pharmacy and pharmacology 20090401

• Antiplatelet effects of piplartine, an alkamide isolated from Piper tuberculatum: possible involvement of cyclooxygenase blockade and antioxidant activity.

  The Journal of pharmacy and pharmacology 20090401

• Levels of prostaglandin E metabolite and leukotriene E(4) are increased in the urine of smokers: evidence that celecoxib shunts arachidonic acid into the 5-lipoxygenase pathway.

  Cancer prevention research (Philadelphia, Pa.) 20090401

• Arachidonic acid-containing phosphatidylcholine species are increased in selected brain regions of a depressive animal model: implications for pathophysiology.

  Prostaglandins, leukotrienes, and essential fatty acids 20090401

• Fatty acid CoA ligase-4 gene polymorphism influences fatty acid metabolism in metabolic syndrome, but not in depression.

  The Tohoku journal of experimental medicine 20090401

• Cyclooxygenase-1 haplotype C50T/A-842G does not affect platelet response to aspirin.

  Thrombosis and haemostasis 20090401

• Dietary linoleic acid has no effect on arachidonic acid, but increases n-6 eicosadienoic acid, and lowers dihomo-gamma-linolenic and eicosapentaenoic acid in plasma of adult men.

  Prostaglandins, leukotrienes, and essential fatty acids 20090401

• Prevention of seizure-induced up-regulation of endothelial P-glycoprotein by COX-2 inhibition.

  Neuropharmacology 20090401

• Suppression of adipogenesis program in cultured preadipocytes transfected stably with cyclooxygenase isoforms.

  Biochimica et biophysica acta 20090401

• Effects of pomegranate juice and extract polyphenols on platelet function.

  Journal of medicinal food 20090401

• Safety evaluation of arachidonic acid rich Mortierella alpina biomass in albino rats--a subchronic study.

  Regulatory toxicology and pharmacology : RTP 20090401

• Cardiovascular effects of centrally administered arachidonic acid in haemorrhage-induced hypotensive rats: investigation of a peripheral mechanism.

  Clinical and experimental pharmacology & physiology 20090401

• Acute lung injury is reduced in fat-1 mice endogenously synthesizing n-3 fatty acids.

  American journal of respiratory and critical care medicine 20090315

• Coordinate regulation of TLR-mediated arachidonic acid mobilization in macrophages by group IVA and group V phospholipase A2s.

  Journal of immunology (Baltimore, Md. : 1950) 20090315

• Docosahexaenoic acid suppresses arachidonic acid-induced proliferation of LS-174T human colon carcinoma cells.

  World journal of gastroenterology 20090307

• AMPA receptor-mediated cell death is reduced by docosahexaenoic acid but not by eicosapentaenoic acid in area CA1 of hippocampal slice cultures.

  Journal of neuroscience research 20090301

• Oxygen-glucose deprivation activates 5-lipoxygenase mediated by oxidative stress through the p38 mitogen-activated protein kinase pathway in PC12 cells.

  Journal of neuroscience research 20090301

• Epoxyeicosatrienoic acid activates BK channels in the cortical collecting duct.

  Journal of the American Society of Nephrology : JASN 20090301

• In vitro decidualization of rat endometrial stromal cells.

  Cell and tissue research 20090301

• Chronic hypoxia enhances 15-lipoxygenase-mediated vasorelaxation in rabbit arteries.

  American journal of physiology. Heart and circulatory physiology 20090301

• Attenuated PGI2 synthesis in obese Zucker rats.

  American journal of physiology. Regulatory, integrative and comparative physiology 20090301

• Acute nicotine reduces brain arachidonic acid signaling in unanesthetized rats.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20090301

• Characterization of the pattern of the nongenomic signaling pathway through which TCDD-induces early inflammatory responses in U937 human macrophages.

  Chemosphere 20090301

• Effects of synthetic sphingosine-1-phosphate analogs on cytosolic phospholipase A2alpha-independent release of arachidonic acid and cell toxicity in L929 fibrosarcoma cells: the structure-activity relationship.

  Journal of pharmacological sciences 20090301

• Long-chain polyunsaturated fatty acids as anti-HIV supplementation during breastfeeding.

  Taiwanese journal of obstetrics & gynecology 20090301

• Metabolic profile of plasma free fatty acids in patients with aspirin-intolerant urticaria.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20090301

• Cytosolic phospholipase A2-driven PGE2 synthesis within unsaturated fatty acids-induced lipid bodies of epithelial cells.

  Biochimica et biophysica acta 20090301

• [Blood platelets metabolic and activation processes and options for their inhibition].

  Vnitrni lekarstvi 20090301

• A novel hypothesis regarding the possible involvement of cytosolic phospholipase 2 in insulin-stimulated proliferation of vascular smooth muscle cells.

  Cell biology international 20090301

• [Controlling arachidonic acid metabolic network: from single- to multi-target inhibitors of key enzymes].

  Yao xue xue bao = Acta pharmaceutica Sinica 20090301

• Inhibition of calcium-independent phospholipase A2 prevents inflammatory mediator production in pulmonary microvascular endothelium.

  Respiratory physiology & neurobiology 20090227

• Activation of cytosolic phospholipase A2-{alpha} as a novel mechanism regulating endothelial cell cycle progression and angiogenesis.

  The Journal of biological chemistry 20090227

• Adsorption of GST-PI3Kgamma at the air-buffer interface and at substrate and nonsubstrate phospholipid monolayers.

  Biophysical journal 20090204

• Fatty acid composition of erythrocyte membrane lipids in healthy subjects from birth to young adulthood.

  European journal of pediatrics 20090201

• Relationship between aspirin and clopidogrel responses in acute coronary syndrome and clinical predictors of non response.

  Thrombosis research 20090201

• Regular consumption of n-3 fatty acid-enriched pork modifies cardiovascular risk factors.

  The British journal of nutrition 20090201

• Fatty acids induce apoptosis in human smooth muscle cells depending on chain length, saturation, and duration of exposure.

  Atherosclerosis 20090201

• Associations between neonatal birth dimensions and maternal essential and trans fatty acid contents during pregnancy and at delivery.

  The British journal of nutrition 20090201

• Anti-inflammatory effects of long-chain n-3 PUFA in rhinovirus-infected cultured airway epithelial cells.

  The British journal of nutrition 20090201

• Regulation of the murine TRPP3 channel by voltage, pH, and changes in cell volume.

  Pflugers Archiv : European journal of physiology 20090201

• Transient receptor potential vanilloid-1 signaling as a regulator of human sebocyte biology.

  The Journal of investigative dermatology 20090201

• Low peripheral progesterone and late embryonic/early fetal loss in suckled beef and lactating dairy cows.

  Theriogenology 20090201

• Critical role of COX-1 in prostacyclin production by human endothelial cells under modification of hydroperoxide tone.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20090201

• Effect of dietary levels of corn oil on maternal arachidonic acid synthesis and fatty acid composition in lactating rats.

  Nutrition (Burbank, Los Angeles County, Calif.) 20090201

• Supplementation of a low dose of DHA or DHA+AA does not prevent peripartum depressive symptoms in a small population based sample.

  Progress in neuro-psychopharmacology & biological psychiatry 20090201

• Chronic risperidone treatment preferentially increases rat erythrocyte and prefrontal cortex omega-3 fatty acid composition: evidence for augmented biosynthesis.

  Schizophrenia research 20090201

• Clinical and laboratory phenotypes associated with the aspirin-like defect: a study in 17 unrelated families.

  British journal of haematology 20090201

• Possible mediators of connecting tubule glomerular feedback.

  Hypertension (Dallas, Tex. : 1979) 20090201

• Angiotensin-(1-7) activates growth-stimulatory pathways in human mesangial cells.

  American journal of physiology. Renal physiology 20090201

• PPARdelta is a ligand-dependent negative regulator of vitamin D3-induced monocyte differentiation.

  Carcinogenesis 20090201

• Dietary n-6 PUFA deprivation for 15 weeks reduces arachidonic acid concentrations while increasing n-3 PUFA concentrations in organs of post-weaning male rats.

  Biochimica et biophysica acta 20090201

• Constitutive COX-2 activity in cardiomyocytes confers permanent cardioprotection Constitutive COX-2 expression and cardioprotection.

  Journal of molecular and cellular cardiology 20090201

• Cytosolic phospholipase A2-{alpha} is an early apoptotic activator in PEDF-induced endothelial cell apoptosis.

  American journal of physiology. Cell physiology 20090201

• Leptin-induced cytosolic phospholipase A2 activation in gastric mucosal protection against ethanol cytotoxicity involves epidermal growth factor receptor transactivation.

  Inflammopharmacology 20090201

• Expression of phospholipases A2 in primary human lung macrophages: role of cytosolic phospholipase A2-alpha in arachidonic acid release and platelet activating factor synthesis.

  Biochimica et biophysica acta 20090201

• Differential effects of malignant mesothelioma cells on THP-1 monocytes and macrophages.

  International journal of oncology 20090201

• The effect of ex vivo anticoagulants on whole blood platelet aggregation.

  Platelets 20090201

• Oxidative stress, nitric oxide and prostaglandin E2 levels in the gastrointestinal tract of aging rats.

  The Journal of pharmacy and pharmacology 20090201

• Swelling-activated Cl(-) current in isolated rabbit articular chondrocytes: inhibition by arachidonic Acid.

  Journal of pharmacological sciences 20090201

• Effects of dietary Spirulina on vascular reactivity.

  Journal of medicinal food 20090201

• Nitric oxide-releasing nonsteroidal anti-inflammatory drugs: gastrointestinal-sparing potential drugs.

  Journal of medicinal food 20090201

• Dietary assessment of arachidonic acid and docosahexaenoic acid intake in 4-7 year-old children.

  Journal of the American College of Nutrition 20090201

• Cyclooxygenase-2 inhibition and hypoxia-induced pulmonary hypertension: effects on pulmonary vascular remodeling and contractility.

  Trends in cardiovascular medicine 20090201

• Morinda citrifolia Linn (Noni): in vivo and in vitro reproductive toxicology.

  Journal of ethnopharmacology 20090121

• Peripheral delta opioid receptors require priming for functional competence in vivo.

  European journal of pharmacology 20090114

• Structural insight into PPARgamma activation through covalent modification with endogenous fatty acids.

  Journal of molecular biology 20090109

• Inhibition of platelet GPIIb-IIIa and P-selectin expression by aspirin is impaired by stress hyperglycemia.

  Journal of diabetes and its complications 20090101

• Enhancing arachidonic acid production by Mortierella alpina ME-1 using improved mycelium aging technology.

  Bioprocess and biosystems engineering 20090101

• Investigating the inflammatory phenotype of major depression: focus on cytokines and polyunsaturated fatty acids.

  Journal of psychiatric research 20090101

• Structural equations to model relationships between pulmonary function, fatty acids and oxidation in cystic fibrosis.

  Scandinavian journal of clinical and laboratory investigation 20090101

• IPD meta-analysis shows no effect of LC-PUFA supplementation on infant growth at 18 months.

  Acta paediatrica (Oslo, Norway : 1992) 20090101

• Relative efficacies of alpha-tocopherol, N-acetyl-serotonin, and melatonin in reducing non-enzymatic lipid peroxidation of rat testicular microsomes and mitochondria.

  Molecular and cellular biochemistry 20090101

• Inhibition of arachidonic acid and iron-induced mitochondrial dysfunction and apoptosis by oltipraz and novel 1,2-dithiole-3-thione congeners.

  Molecular pharmacology 20090101

• Association with actin mediates the EGTA-resistant binding of cytosolic phospholipase A2-alpha to the plasma membrane of activated platelets.

  Cell biology international 20090101

• Inhibitory activity of salicylic acid on lipoxygenase-dependent lipid peroxidation.

  Biochimica et biophysica acta 20090101

• Arachidonic acid increases antifungal susceptibility of Candida albicans and Candida dubliniensis.

  The Journal of antimicrobial chemotherapy 20090101

• Inhibition of serine/threonine phosphatase enhances arachidonic acid-induced [Ca2+]i via protein kinase A.

  American journal of physiology. Cell physiology 20090101

• Upregulation of Fas and FasL in Taiwan cobra phospholipase A2-treated human neuroblastoma SK-N-SH cells through ROS- and Ca2+-mediated p38 MAPK activation.

  Journal of cellular biochemistry 20090101

• Long-chain polyunsaturated fatty acid transport across human placental choriocarcinoma (BeWo) cells.

  Placenta 20090101

• Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects.

  Nature chemical biology 20090101

• Relaxation evoked by extracellular Ca2+ in rat aorta is nerve-independent and involves sarcoplasmic reticulum and L-type Ca2+ channel.

  Vascular pharmacology 20090101

• Antiplatelet activity of beta-carboline alkaloids from Perganum harmala: a possible mechanism through inhibiting PLCgamma2 phosphorylation.

  Vascular pharmacology 20090101

• 15-HETE suppresses K(+) channel activity and inhibits apoptosis in pulmonary artery smooth muscle cells.

  Apoptosis : an international journal on programmed cell death 20090101

• Effects of arachidonic acid and docosahexaenoic acid on differentiation and mineralization of MC3T3-E1 osteoblast-like cells.

  Cell biochemistry and function 20090101

• Growth inhibition and induction of apoptosis of colon cancer cell lines by applying marine phospholipid.

  Nutrition and cancer 20090101

• Human milk arachidonic acid and docosahexaenoic acid contents increase following supplementation during pregnancy and lactation.

  Prostaglandins, leukotrienes, and essential fatty acids 20090101

• Identification of mutation sites on omega3 desaturase genes from Mortierella alpina 1S-4 mutants.

  Journal of bioscience and bioengineering 20090101

• What happened to do no harm? The issue of dietary omega-6 fatty acids.

  Prostaglandins, leukotrienes, and essential fatty acids 20090101

• The enteropathy of prostaglandin deficiency.

  Journal of gastroenterology 20090101

• n3 and n6 polyunsaturated fatty acids differentially modulate prostaglandin E secretion but not markers of lipogenesis in adipocytes.

  Nutrition & metabolism 20090101

• Antiplatelet activity of Allium ursinum and Allium sativum.

  Pharmacology 20090101

• A randomised control trial in schoolchildren showed improvement in cognitive function after consuming a bread spread, containing fish flour from a marine source.

  Prostaglandins, leukotrienes, and essential fatty acids 20090101

• Fatty acid uptake by breast cancer cells (MDA-MB-231): effects of insulin, leptin, adiponectin, and TNFalpha.

  Prostaglandins, leukotrienes, and essential fatty acids 20090101

• EPA and DHA suppress AngII- and arachidonic acid-induced expression of profibrotic genes in human mesangial cells.

  Journal of nephrology 20090101

• Total red blood cell concentrations of omega-3 fatty acids are associated with emotion-elicited neural activity in adolescent boys with attention-deficit hyperactivity disorder.

  Prostaglandins, leukotrienes, and essential fatty acids 20090101

• Cytochrome P450 metabolites of arachidonic acid play a role in the enhanced cardiac dysfunction in diabetic rats following ischaemic reperfusion injury.

  Autonomic & autacoid pharmacology 20090101

• Arachidonic acid increases matrix metalloproteinase 9 secretion and expression in human monocytic MonoMac 6 cells.

  Lipids in health and disease 20090101

• Arachidonic acid drives postnatal neurogenesis and elicits a beneficial effect on prepulse inhibition, a biological trait of psychiatric illnesses.

  PloS one 20090101

• Antineoplastic effects of n-3 polyunsaturated fatty acids in combination with drugs and radiotherapy: preventive and therapeutic strategies.

  Nutrition and cancer 20090101

• [Wound healing and induced resistance in potato tubers].

  Prikladnaia biokhimiia i mikrobiologiia 20090101

• [Breeding of arachidonic acid producing Mortierella sabellina by ultraviolet mutation].

  Wei sheng wu xue bao = Acta microbiologica Sinica 20090101

• Responses of astrocyte to simultaneous glutamate and arachidonic acid treatment.

  Neurochemistry international 20090101

• Inhibition of secretory phospholipase A2-induced cytokine production in human lung macrophages by budesonide.

  International archives of allergy and immunology 20090101

• Nutrition for the eye: different susceptibility of the retina and the lacrimal gland to dietary omega-6 and omega-3 polyunsaturated fatty acid incorporation.

  Ophthalmic research 20090101

• Homeopathic treatment of Arabidopsis thaliana plants infected with Pseudomonas syringae.

  TheScientificWorldJournal 20090101

• Variability in aggregometry response before and after initiation of clopidogrel therapy.

  Scandinavian journal of clinical and laboratory investigation 20090101

• Long chain polyunsaturated fatty acids in mothers and term babies.

  Journal of perinatal medicine 20090101

• Vitamin E paradox in Alzheimer's disease: it does not prevent loss of cognition and may even be detrimental.

  Journal of Alzheimer's disease : JAD 20090101

• Antineoplastic effect of iodine in mammary cancer: participation of 6-iodolactone (6-IL) and peroxisome proliferator-activated receptors (PPAR).

  Molecular cancer 20090101

• Toward optimizing vision and cognition in term infants by dietary docosahexaenoic and arachidonic acid supplementation: a review of randomized controlled trials.

  Prostaglandins, leukotrienes, and essential fatty acids 20090101

• Dietary docosahexaenoic acid but not arachidonic acid influences central nervous system fatty acid status in baboon neonates.

  Prostaglandins, leukotrienes, and essential fatty acids 20090101

• [Blood cell phagocytic activity and free fatty acids content in rat brain in modeling of the brain blood supply disorders].

  Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20090101

• Trans isomeric and LCPUFA are inversely correlated in erythrocyte membrane lipids at mid-gestation.

  Advances in experimental medicine and biology 20090101

• The essentiality of arachidonic acid and docosahexaenoic acid.

  Prostaglandins, leukotrienes, and essential fatty acids 20090101

• Long-term ingestion of reduced glutathione suppressed an accelerating effect of beef tallow diet on colon carcinogenesis in rats.

  Journal of gastroenterology 20090101

• Role of the calcium channel in blastocyst implantation: a novel contraceptive target.

  Journal of basic and clinical physiology and pharmacology 20090101

• Glucocorticoid-regulated crosstalk between arachidonic acid and endocannabinoid biochemical pathways coordinates cognitive-, neuroimmune-, and energy homeostasis-related adaptations to stress.

  Vitamins and hormones 20090101

• Evolutionary aspects of the dietary omega-6:omega-3 fatty acid ratio: medical implications.

  World review of nutrition and dietetics 20090101

• Resveratrol inhibits prostaglandin formation in IL-1beta-stimulated SK-N-SH neuronal cells.

  Journal of neuroinflammation 20090101

• Arachidonic acid supplementation decreases P300 latency and increases P300 amplitude of event-related potentials in healthy elderly men.

  Neuropsychobiology 20090101

• 15-lipoxygenase-1 in colorectal cancer: a review.

  Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20090101

• Three randomized controlled trials of early long-chain polyunsaturated Fatty Acid supplementation on means-end problem solving in 9-month-olds.

  Child development 20090101

• Arachidonic acid and calcium signals in human breast tumor-derived endothelial cells: a proteomic study.

  Journal of receptor and signal transduction research 20090101

• Optimal dose of preoperative enteral immunonutrition for patients with esophageal cancer.

  Surgery today 20090101

• Effects of fatty acids on metabolism and cell growth of human colon cell lines of different transformation state.

  BioFactors (Oxford, England) 20090101

• Neuroprotective effect of N-acetylcysteine in neurons exposed to arachidonic acid during simulated ischemia in vitro.

  Pharmacological reports : PR 20090101

• A meta-analysis of blood fatty acids in people with learning disorders with particular interest in arachidonic acid.

  Prostaglandins, leukotrienes, and essential fatty acids 20090101

• Arachidonic and docosahexaenoic acid deficits in preterm neonatal mononuclear cell membranes. Implications for the immune response at birth.

  Nutrition and health 20090101

• Maternal arachidonic acid supplementation improves neurodevelopment of offspring from healthy and diabetic rats.

  Prostaglandins, leukotrienes, and essential fatty acids 20090101

• Effects of N-acetylcysteine and ebselen on arachidonic acid release from astrocytes and neurons cultured in normoxic or simulated ischemic conditions.

  Pharmacological reports : PR 20090101

• [Antiaggregant properties of new 1,3,4-thiadiazine derivatives].

  Eksperimental'naia i klinicheskaia farmakologiia 20090101

• Arachidonic acid-induced apoptosis in rat hepatoma AS-30D cells is mediated by reactive oxygen species.

  Acta biochimica Polonica 20090101

• Pantoprazole may enhance antiplatelet effect of enteric-coated aspirin in patients with acute coronary syndrome.

  Cardiology journal 20090101

• Propofol suppresses prostaglandin E(2) production in human peripheral monocytes.

  Immunopharmacology and immunotoxicology 20090101

• Jasmonic acid and tomato resistance to the root-knot nematode Meloidogyne incognita.

  Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections 20090101

• Correlation of omega-3 levels in serum phospholipid from 2053 human blood samples with key fatty acid ratios.

  Nutrition journal 20090101

• Omega-3 and omega-6 polyunsaturated fatty acids enhance arsenic trioxide efficacy in arsenic trioxide-resistant leukemic and solid tumor cells.

  Oncology research 20090101

• [Effects of arachidonic acids on social behavior in patients with autism spectrum disorders].

  Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica 20090101

• Zileuton, a new efficient and safe systemic anti-acne drug.

  Dermato-endocrinology 20090101

• Regulation of endothelial cell functions by basement membrane- and arachidonic acid-derived products.

  Wiley interdisciplinary reviews. Systems biology and medicine 20090101

• Co-oxidation by cyclooxygenases.

  Current protocols in toxicology 20090101

• Significance of the nongenomic, inflammatory pathway in mediating the toxic action of TCDD to induce rapid and long-term cellular responses in 3T3-L1 adipocytes.

  Biochemistry 20081230

• Formation of dopamine adducts derived from brain polyunsaturated fatty acids: mechanism for Parkinson disease.

  The Journal of biological chemistry 20081212

• Discovery and development of fatty acid amide hydrolase (FAAH) inhibitors.

  Journal of medicinal chemistry 20081211

• Smooth muscle cell arachidonic acid release, migration, and proliferation are markedly attenuated in mice null for calcium-independent phospholipase A2beta.

  The Journal of biological chemistry 20081205

• Bradykinin stimulates glutamate uptake via both B1R and B2R activation in a human retinal pigment epithelial cells.

  Life sciences 20081205

• Synthesis and evaluation of 4-amino-3,4-dihydro-2H-naphthalen-1-one derivatives as mast cell stabilising and anti-inflammatory compounds.

  European journal of medicinal chemistry 20081201

• Dual elicitation for improved production of withaferin A by cell suspension cultures of Withania somnifera.

  Applied biochemistry and biotechnology 20081201

• The cytotoxic effect of bromoenol lactone, a calcium-independent phospholipase A2 inhibitor, on rat cortical neurons in culture.

  Cellular and molecular neurobiology 20081201

• Angiotensin metabolites can stimulate receptors of the Mas-related genes family.

  Molecular and cellular biochemistry 20081201

• Strong activation of cyclooxygenase I and II catalytic activity by dietary bioflavonoids.

  Journal of lipid research 20081201

• Increased blood pressure in mice lacking cytochrome P450 2J5.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20081201

• Mechanism of modulation of the plasma membrane Ca(2+)-ATPase by arachidonic acid.

  Prostaglandins & other lipid mediators 20081201

• Functional analysis of a fatty acid elongase from arachidonic acid-producing Mortierella alpina 1S-4.

  Applied microbiology and biotechnology 20081201

• Differential crosstalk between P2X7 and arachidonic acid in activation of mitogen-activated protein kinases.

  Neurochemistry international 20081201

• Virodhamine relaxes the human pulmonary artery through the endothelial cannabinoid receptor and indirectly through a COX product.

  British journal of pharmacology 20081201

• Signaling pathways involved in the antiproliferative effect of molecular iodine in normal and tumoral breast cells: evidence that 6-iodolactone mediates apoptotic effects.

  Endocrine-related cancer 20081201

• Hypercholesterolemia enhances 15-lipoxygenase-mediated vasorelaxation and acetylcholine-induced hypotension.

  Arteriosclerosis, thrombosis, and vascular biology 20081201

• Large-scale expression, purification, and characterization of an engineered prostacyclin-synthesizing enzyme with therapeutic potential.

  Archives of biochemistry and biophysics 20081201

• Control of the single channel conductance of K2P10.1 (TREK-2) by the amino-terminus: role of alternative translation initiation.

  The Journal of physiology 20081201

• Ca2+-independent PLA2 controls endothelial store-operated Ca2+ entry and vascular tone in intact aorta.

  American journal of physiology. Heart and circulatory physiology 20081201

• 7beta-hydroxy-epiandrosterone modulation of 15-deoxy-delta12,14-prostaglandin J2, prostaglandin D2 and prostaglandin E2 production from human mononuclear cells.

  The Journal of steroid biochemistry and molecular biology 20081201

• Ethanol and arachidonic acid synergize to activate Kupffer cells and modulate the fibrogenic response via tumor necrosis factor alpha, reduced glutathione, and transforming growth factor beta-dependent mechanisms.

  Hepatology (Baltimore, Md.) 20081201

• Calcium-independent phospholipase A2-mediated formation of 1,2-diarachidonoyl-glycerophosphoinositol in monocytes.

  The FEBS journal 20081201

• The phosphoinositide 3-kinase-dependent activation of Btk is required for optimal eicosanoid production and generation of reactive oxygen species in antigen-stimulated mast cells.

  Journal of immunology (Baltimore, Md. : 1950) 20081201

• An evaluation of cyclooxygenase-1 inhibition before coronary artery surgery: aggregometry versus patient self-reporting.

  Anesthesia and analgesia 20081201

• An active triple-catalytic hybrid enzyme engineered by linking cyclo-oxygenase isoform-1 to prostacyclin synthase that can constantly biosynthesize prostacyclin, the vascular protector.

  The FEBS journal 20081201

• Omega-6 and trans fatty acids in blood cell membranes: a risk factor for acute coronary syndromes?

  American heart journal 20081201

• Relationships between intestinal polyp formation and fatty acid levels in plasma, erythrocytes, and intestinal polyps in Min mice.

  Cancer science 20081201

• Expression of human peroxisome proliferator-activated receptors ligand binding domain-maltose binding protein fusion protein in Escherichia coli: a convenient and reliable method for preparing receptor for screening ligands.

  Assay and drug development technologies 20081201

• Anti-allergic activity of an ethanol extract from Salviae miltiorrhiza.

  Archives of pharmacal research 20081201

• Predicting thrombotic events: creating a complex approach for a complex condition.

  Thrombosis and haemostasis 20081201

• Thrombotic events in high risk patients are predicted by evaluating different pathways of platelet function.

  Thrombosis and haemostasis 20081201

• Fatty acid composition in breast milk from 4 regions of Thailand.

  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20081201

• Arachidonic acid metabolites inhibit the stimulatory effect of angiotensin II in renal proximal tubules.

  Hypertension research : official journal of the Japanese Society of Hypertension 20081201

• Cytochrome P-450 metabolites in renal circulation and excretion--interaction with the nitric oxide (NO) system.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20081201

• Role of phospholipase A2 in activation of isolated cardiomyocyte respiration in postinfarction cardiosclerosis.

  Bulletin of experimental biology and medicine 20081201

• D609, an inhibitor of phosphatidylcholine-specific phospholipase C, inhibits group IV cytosolic phospholipase A2.

  Molecules and cells 20081130

• Structures of human cytochrome P-450 2E1. Insights into the binding of inhibitors and both small molecular weight and fatty acid substrates.

  The Journal of biological chemistry 20081128

• Synthesis of 11-thialinoleic acid and 14-thialinoleic acid, inhibitors of soybean and human lipoxygenases.

  Organic & biomolecular chemistry 20081121

• ASIC3, a sensor of acidic and primary inflammatory pain.

  The EMBO journal 20081119

• Monoacylglycerol lipase regulates 2-arachidonoylglycerol action and arachidonic acid levels.

  Bioorganic & medicinal chemistry letters 20081115

• Kinetic isotope effects in the oxidation of arachidonic acid by soybean lipoxygenase-1.

  Bioorganic & medicinal chemistry letters 20081115

• Ajulemic acid, a synthetic cannabinoid acid, induces an antiinflammatory profile of eicosanoids in human synovial cells.

  Life sciences 20081107

• Chronic administration of valproic acid reduces brain NMDA signaling via arachidonic acid in unanesthetized rats.

  Neurochemical research 20081101

• Production and recovery of polyunsaturated fatty acids-added lipids from fermented canola.

  Bioresource technology 20081101

• Vasotocin has the potential to inhibit basolateral Na(+)/K (+)-pump current across isolated skin of tree frog in vitro, via its V(2)-type receptor/cAMP pathway.

  Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20081101

• Phosphatidylinositol-bisphosphate regulates intercellular coupling in cardiac myocytes.

  Pflugers Archiv : European journal of physiology 20081101

• 5-LOX, 12-LOX and 15-LOX in immature forms of human leukemic blasts.

  Leukemia research 20081101

• Chronic d-amphetamine depresses an imaging marker of arachidonic acid metabolism in rat brain.

  The international journal of neuropsychopharmacology 20081101

• The endocannabinoid anandamide is a substrate for the human polymorphic cytochrome P450 2D6.

  The Journal of pharmacology and experimental therapeutics 20081101

• Modulation of cytochrome P450 gene expression and arachidonic acid metabolism during isoproterenol-induced cardiac hypertrophy in rats.

  Drug metabolism and disposition: the biological fate of chemicals 20081101

• Aspirin and the in vitro linear relationship between thromboxane A2-mediated platelet aggregation and platelet production of thromboxane A2.

  Journal of thrombosis and haemostasis : JTH 20081101

• Liver TAG transiently decreases while PL n-3 and n-6 fatty acids are persistently elevated in insulin resistant mice.

  Lipids 20081101

• Role of cytochrome P450 2C8 and 2J2 genotypes in calcineurin inhibitor-induced chronic kidney disease.

  Pharmacogenetics and genomics 20081101

• Laminar shear stress inhibits lipid peroxidation induced by high glucose plus arachidonic acid in endothelial cells.

  American journal of physiology. Heart and circulatory physiology 20081101

• Arachidonic acid promotes FAK activation and migration in MDA-MB-231 breast cancer cells.

  Experimental cell research 20081101

• Role of CYP epoxygenases in A2A AR-mediated relaxation using A2A AR-null and wild-type mice.

  American journal of physiology. Heart and circulatory physiology 20081101

• Maternal di-(2-ethylhexyl)-phthalate exposure influences essential fatty acid homeostasis in rat placenta.

  Placenta 20081101

• (3S)-N-(L-Aminoacyl)-1,2,3,4-tetrahydroisoquinolines, a class of novel antithrombotic agents: synthesis, bioassay, 3D QSAR, and ADME analysis.

  Bioorganic & medicinal chemistry 20081101

• Role of long-chain polyunsaturated fatty acids in the first year of life.

  Journal of pediatric gastroenterology and nutrition 20081101

• Hypoallergenicity and effects on growth and tolerance of a new amino acid-based formula with DHA and ARA.

  Journal of pediatric gastroenterology and nutrition 20081101

• Indomethacin decreases arachidonic acid uptake in HCA-7 human colon cancer cells.

  Journal of pharmacological sciences 20081101

• Akt kinase reducing endoplasmic reticulum Ca2+ release protects cells from Ca2+-dependent apoptotic stimuli.

  Biochemical and biophysical research communications 20081031

• Lysophospholipid acyltransferases and arachidonate recycling in human neutrophils.

  The Journal of biological chemistry 20081031

• High dietary omega-6 fatty acids contribute to reduced docosahexaenoic acid in the developing brain and inhibit secondary neurite growth.

  Brain research 20081027

• Alterations of concentrations of calcium and arachidonic acid and agglutinations of microfilaments in host cells during Toxoplasma gondii invasion.

  Veterinary parasitology 20081020

• Eicosapentaenoic-acid-derived isoprostanes: synthesis and discovery of two major isoprostanes.

  Bioorganic & medicinal chemistry letters 20081015

• Multi-targeted therapy of cancer by omega-3 fatty acids.

  Cancer letters 20081008

• Influence of phenolic constituents from Yucca schidigera bark on arachidonate metabolism in vitro.

  Journal of agricultural and food chemistry 20081008

• Effect of dietary supplementation with increasing doses of docosahexaenoic acid on neutrophil lipid composition and leukotriene production in human healthy volunteers.

  The British journal of nutrition 20081001

• Involvement of PPARalpha in the growth inhibitory effect of arachidonic acid on breast cancer cells.

  The British journal of nutrition 20081001

• Expression of CYP4A1 in U251 human glioma cell induces hyperproliferative phenotype in vitro and rapidly growing tumors in vivo.

  The Journal of pharmacology and experimental therapeutics 20081001

• UVB light upregulates prostaglandin synthases and prostaglandin receptors in mouse keratinocytes.

  Toxicology and applied pharmacology 20081001

• 12/15-Lipoxygenase activity increases the degradation of macrophage ATP-binding cassette transporter G1.

  Arteriosclerosis, thrombosis, and vascular biology 20081001

• Regulation of Wnt/beta-catenin pathway by cPLA2alpha and PPARdelta.

  Journal of cellular biochemistry 20081001

• In vitro allergen challenge of peripheral blood induces differential gene expression in mononuclear cells of asthmatic patients: inhibition of cytosolic phospholipase A2alpha overcomes the asthma-associated response.

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20081001

• Multiple anti-atherosclerotic treatments impair aspirin compliance: effects on aspirin resistance.

  Journal of thrombosis and haemostasis : JTH 20081001

• Urine stimulation activates BK channels in mouse vomeronasal neurons.

  Journal of neurophysiology 20081001

• Increased arachidonic acid-induced thromboxane generation impairs skeletal muscle arteriolar dilation with genetic dyslipidemia.

  Microcirculation (New York, N.Y. : 1994) 20081001

• An investigation into the role of prostaglandins in zebrafish oocyte maturation and ovulation.

  General and comparative endocrinology 20081001

• Effects of omega-3 and -6 fatty acids on Mycobacterium tuberculosis in macrophages and in mice.

  Microbes and infection 20081001

• Arachidonic-acid-derived eicosanoids: roles in biology and immunopathology.

  Trends in molecular medicine 20081001

• Saturated and unsaturated (including arachidonic acid) non-esterified fatty acid modulation of insulin secretion from pancreatic beta-cells.

  Biochemical Society transactions 20081001

• Paracetamol (Acetaminophen): mechanisms of action.

  Paediatric anaesthesia 20081001

• Acute coronary syndrome patients with depression have low blood cell membrane omega-3 fatty acid levels.

  Psychosomatic medicine 20081001

• Effects of psychotropic drugs on the thrombin-induced liberation of arachidonate in human platelets.

  Saudi medical journal 20081001

• Deficits in docosahexaenoic acid and associated elevations in the metabolism of arachidonic acid and saturated fatty acids in the postmortem orbitofrontal cortex of patients with bipolar disorder.

  Psychiatry research 20080930

• Cytosolic PLA2(alpha) activation in Purkinje neurons and its role in AMPA-receptor trafficking.

  Journal of cell science 20080915

• Synthesis of all-trans anandamide: a substrate for fatty acid amide hydrolase with dual effects on rabbit platelet activation.

  Bioorganic & medicinal chemistry 20080915

• Identification of novel endogenous cytochrome p450 arachidonate metabolites with high affinity for cannabinoid receptors.

  The Journal of biological chemistry 20080905

• Nipple aspirate fluids from women with breast cancer contain increased levels of group IIa secretory phospholipase A2.

  Breast cancer research and treatment 20080901

• Regulation of cytosolic phospholipase A2alpha by hsp90 and a p54 kinase in okadaic acid-stimulated macrophages.

  Journal of leukocyte biology 20080901

• Arachidonic acid and ion channels: an update.

  British journal of pharmacology 20080901

• Role of polyunsaturated fatty acids in the management of Egyptian children with autism.

  Clinical biochemistry 20080901

• Secretory phospholipases A(2) isolated from Bothrops asper and from Crotalus durissus terrificus snake venoms induce distinct mechanisms for biosynthesis of prostaglandins E2 and D2 and expression of cyclooxygenases.

  Toxicon : official journal of the International Society on Toxinology 20080901

• Fatty acid composition abnormalities in atopic disease: evidence explored and role in the disease process examined.

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20080901

• Imaging neuroinflammation in Alzheimer's disease with radiolabeled arachidonic acid and PET.

  Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20080901

• Selenium status in patients with aspirin-induced asthma.

  Annals of clinical biochemistry 20080901

• Epoxyeicosatrienoic acids and/or their metabolites promote hypoxic response of cells.

  Journal of pharmacological sciences 20080901

• Anti-inflammatory activity of the ethanol extract of Chungkukjang, Korean fermented bean: 5-lipoxygenase inhibition.

  Journal of medicinal food 20080901

• Phospholipid membrane abnormalities and reduced niacin skin flush response in schizophrenia.

  Psychiatria Danubina 20080901

• Testing agonist-induced platelet aggregation by the Impact-R [Cone and plate(let) analyzer (CPA)].

  Platelets 20080901

• Low magnesium stimulated prostacyclin generation in cultured human endothelial cells.

  Magnesium research 20080901

• Cytosolic phospholipase A(2), lipoxygenase metabolites, and reactive oxygen species.

  BMB reports 20080831

• Expression of the cytochrome P450 epoxygenase CYP2J2 in human monocytic leukocytes.

  Life sciences 20080829

• Release of arachidonic acid by 2-arachidonoyl glycerol and HU210 in PC12 cells; roles of Src, phospholipase C and cytosolic phospholipase A(2)alpha.

  European journal of pharmacology 20080820

• Structural basis for induced formation of the inflammatory mediator prostaglandin E2.

  Proceedings of the National Academy of Sciences of the United States of America 20080812

• Alterations in phospholipid and fatty acid lipid profiles in primary neocortical cells during oxidant-induced cell injury.

  Chemico-biological interactions 20080811

• Effects of docosahexaenoic acid on some megakaryocytic cell gene expression of some enzymes controlling prostanoid synthesis.

  Biochemical and biophysical research communications 20080808

• An arachidonic acid-enriched diet does not result in more colonic inflammation as compared with fish oil- or oleic acid-enriched diets in mice with experimental colitis.

  The British journal of nutrition 20080801

• Arachidonic acid-induced activation of large-conductance potassium channels and membrane hyperpolarization in mouse B cells.

  Pflugers Archiv : European journal of physiology 20080801

• Transcriptional and post-transcriptional mechanisms for lysophosphatidic acid-induced cyclooxygenase-2 expression in ovarian cancer cells.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20080801

• Antiangiogenic effect of inhibitors of cytochrome P450 on rats with glioblastoma multiforme.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20080801

• Redox-active antioxidant modulation of lipid signaling in vascular endothelial cells: vitamin C induces activation of phospholipase D through phospholipase A2, lipoxygenase, and cyclooxygenase.

  Molecular and cellular biochemistry 20080801

• Cytosolic phospholipase A2alpha activation induced by S1P is mediated by the S1P3 receptor in lung epithelial cells.

  American journal of physiology. Lung cellular and molecular physiology 20080801

• Polyunsaturated fatty acids, inflammatory processes and inflammatory bowel diseases.

  Molecular nutrition & food research 20080801

• Hypoallergenicity and effects on growth and tolerance of a new amino acid-based formula with docosahexaenoic acid and arachidonic acid.

  The Journal of pediatrics 20080801

• Cytosolic phospholipase A2 alpha inhibition prevents neuronal NMDA receptor-stimulated arachidonic acid mobilization and prostaglandin production but not subsequent cell death.

  Journal of neurochemistry 20080801

• Characterization of the biochemical and structural phenotypes of four CYP1B1 mutations observed in individuals with primary congenital glaucoma.

  Pharmacogenetics and genomics 20080801

• Increased levels of a particular phosphatidylcholine species in senescent human dermal fibroblasts in vitro.

  Human cell 20080801

• Effects of aspirin and clopidogrel in healthy men measured by platelet aggregation and PFA-100.

  Platelets 20080801

• PPAR alpha and PPAR delta transactivity and p300 binding activity induced by arachidonic acid in colorectal cancer cell line Caco-2.

  Journal of nutritional science and vitaminology 20080801

• Acidic peptides enhanced genistein-dependent inhibition of human platelet aggregation: potential protective effect of digestible peptides plus genistein against atherosclerosis.

  Nutrition research (New York, N.Y.) 20080801

• Impact of para-phenylenediamine on cyclooxygenases expression and prostaglandin formation in human immortalized keratinocytes (HaCaT).

  Toxicology 20080730

• Salicylate enables cochlear arachidonic-acid-sensitive NMDA receptor responses.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20080716

• Characterization of the tetratricopeptide-containing domain of BUB1, BUBR1, and PP5 proves that domain amphiphilicity over amino acid sequence specificity governs protein adsorption and interfacial activity.

  The journal of physical chemistry. B 20080710

• Bone resorption varies as a function of time of day and quantity of dietary long chain polyunsaturated fatty acids.

  The Journal of nutritional biochemistry 20080701

• Chronic carbamazepine administration attenuates dopamine D2-like receptor-initiated signaling via arachidonic acid in rat brain.

  Neurochemical research 20080701

• Role for epithelial dysregulation in early-onset colitis-associated colon cancer in Gi2-alpha-/- mice.

  Inflammatory bowel diseases 20080701

• Amyloid beta peptide and NMDA induce ROS from NADPH oxidase and AA release from cytosolic phospholipase A2 in cortical neurons.

  Journal of neurochemistry 20080701

• Lysosomal release of cathepsins causes ischemic damage in the rat hippocampal slice and depends on NMDA-mediated calcium influx, arachidonic acid metabolism, and free radical production.

  Journal of neurochemistry 20080701

• New enzymes involved in the mechanism of action of epidermal growth factor in a clonal strain of Leydig tumor cells.

  Endocrinology 20080701

• Roles of cytosolic phospholipase A2 and Src kinase in the early action of 2,3,7,8-tetrachlorodibenzo-p-dioxin through a nongenomic pathway in MCF10A cells.

  Molecular pharmacology 20080701

• Arachidonic acid-induced expression of the organic solute and steroid transporter-beta (Ost-beta) in a cartilaginous fish cell line.

  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20080701

• A decrease in S-adenosyl-L-methionine potentiates arachidonic acid cytotoxicity in primary rat hepatocytes enriched in CYP2E1.

  Molecular and cellular biochemistry 20080701

• Lipid body mobilization in the ExoU-induced release of inflammatory mediators by airway epithelial cells.

  Microbial pathogenesis 20080701

• Dietary n-3 polyunsaturated fatty acids enhance hormone ablation therapy in androgen-dependent prostate cancer.

  The American journal of pathology 20080701

• Role of the prostaglandin pathway and the use of NSAIDs in genitourinary malignancies.

  Expert review of anticancer therapy 20080701

• The emerging role of docosahexaenoic acid in neuroinflammation.

  Current opinion in investigational drugs (London, England : 2000) 20080701

• Increased platelet sensitivity among individuals with aspirin resistance - platelet aggregation to submaximal concentration of arachidonic acid predicts response to antiplatelet therapy.

  Thrombosis and haemostasis 20080701

• An evaluation of methods for determining reference intervals for light transmission platelet aggregation tests on samples with normal or reduced platelet counts.

  Thrombosis and haemostasis 20080701

• Anti-platelet effects of flavonoids and flavonoid-glycosides from Sophora japonica.

  Archives of pharmacal research 20080701

• [Prostacyclin production in internal mammary ano radial arteries and saphenous veins of diabetic and non diabetic subjects].

  Revista medica de Chile 20080701

• Inhibition effect of arachidonic acid on hypoxia-induced [Ca(2+)](i) elevation in PC12 cells and human pulmonary artery smooth muscle cells.

  Respiratory physiology & neurobiology 20080630

• Regulation of TLR2 expression by prostaglandins in brain glia.

  Journal of immunology (Baltimore, Md. : 1950) 20080615

• A PPAR-independent pathway to PUFA-induced COX-2 expression.

  Molecular and cellular endocrinology 20080611

• Reduction in myocardial ischemia/reperfusion injury in group X secretory phospholipase A2-deficient mice.

  Circulation 20080610

• Brain Natriuretic Peptide (BNP) regulates the production of inflammatory mediators in human THP-1 macrophages.

  Regulatory peptides 20080605

• Inherited human cPLA(2alpha) deficiency is associated with impaired eicosanoid biosynthesis, small intestinal ulceration, and platelet dysfunction.

  The Journal of clinical investigation 20080602

• Fatty acid composition of serum lipid classes in mice following allergic sensitisation with or without dietary docosahexaenoic acid-enriched fish oil substitution.

  The British journal of nutrition 20080601

• Effect of resveratrol, tyrosol and beta-sitosterol on oxidised low-density lipoprotein-stimulated oxidative stress, arachidonic acid release and prostaglandin E2 synthesis by RAW 264.7 macrophages.

  The British journal of nutrition 20080601

• Production of arachidonic acid and dihomo-gamma-linolenic acid from glycerol by oil-producing filamentous fungi, Mortierella in the ARS culture collection.

  Journal of industrial microbiology & biotechnology 20080601

• Boswellic acids: A leukotriene inhibitor also effective through topical application in inflammatory disorders.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20080601

• A novel two-step fermentation process for improved arachidonic acid production by Mortierella alpina.

  Biotechnology letters 20080601

• Free fatty acids act as endogenous ionophores, resulting in Na+ and Ca2+ influx and myocyte apoptosis.

  Cardiovascular research 20080601

• Caffeic acid attenuates the decrease of cortical BDNF transcript IV mRNA induced by swim stress in wild-type but not in 5-lipoxygenase-deficient mice.

  Journal of neural transmission (Vienna, Austria : 1996) 20080601

• Mode of action of mood stabilizers: is the arachidonic acid cascade a common target?

  Molecular psychiatry 20080601

• Silymarin downregulates COX-2 expression and attenuates hyperlipidemia during NDEA-induced rat hepatocellular carcinoma.

  Molecular and cellular biochemistry 20080601

• Activation of cytosolic phospholipase A2 and fatty acid transacylase is essential but not sufficient for thrombin-induced smooth muscle cell proliferation.

  American journal of physiology. Cell physiology 20080601

• Arachidonic acid inhibits basolateral K channels in the cortical collecting duct via cytochrome P-450 epoxygenase-dependent metabolic pathways.

  American journal of physiology. Renal physiology 20080601

• Volume-sensitive NADPH oxidase activity and taurine efflux in NIH3T3 mouse fibroblasts.

  American journal of physiology. Cell physiology 20080601

• Inflammation and genomics in the critical care unit.

  Critical care nursing clinics of North America 20080601

• Activation of the endocannabinoid system by organophosphorus nerve agents.

  Nature chemical biology 20080601

• Pharmacological studies on Indian black tea (leaf variety) in acute and chronic inflammatory conditions.

  Phytotherapy research : PTR 20080601

• Korean red ginseng attenuates hypercholesterolemia-enhanced platelet aggregation through suppression of diacylglycerol liberation in high-cholesterol-diet-fed rabbits.

  Phytotherapy research : PTR 20080601

• Tone-dependent vascular responses to astrocyte-derived signals.

  American journal of physiology. Heart and circulatory physiology 20080601

• Sex differences in vascular function: implication of endothelium-derived hyperpolarizing factor.

  The Journal of endocrinology 20080601

• Delayed inhibition of agonist-induced granulocyte-platelet aggregation after low-dose sevoflurane inhalation in humans.

  Anesthesia and analgesia 20080601

• Different sources of reactive oxygen species contribute to low potassium-induced apoptosis in cerebellar granule cells.

  International journal of molecular medicine 20080601

• Improved cognitive development among preterm infants attributable to early supplementation of human milk with docosahexaenoic acid and arachidonic acid.

  Pediatrics 20080601

• Peripheral mechanisms involved in the pressor and bradycardic effects of centrally administered arachidonic acid.

  Prostaglandins, leukotrienes, and essential fatty acids 20080601

• Enhanced release of sphingosine-1-phosphate from hypercholesterolemic platelets: role in development of hypercholesterolemic atherosclerosis.

  Prostaglandins, leukotrienes, and essential fatty acids 20080601

• Synergistic effects of stress and omega-3 fatty acid deprivation on emotional response and brain lipid composition in adult rats.

  Prostaglandins, leukotrienes, and essential fatty acids 20080601

• Co-oxidation-mediated xenobiotic activation and cytotoxicity by 12-lipoxygenase in intact platelets.

  Toxicology 20080521

• Apigenin inhibits platelet adhesion and thrombus formation and synergizes with aspirin in the suppression of the arachidonic acid pathway.

  Journal of agricultural and food chemistry 20080514

• Non-dioxin-like polychlorinated biphenyls induce a release of arachidonic acid in liver epithelial cells: a partial role of cytosolic phospholipase A(2) and extracellular signal-regulated kinases 1/2 signalling.

  Toxicology 20080502

• Chemical speciation by selective heteronuclear single-quantum coherence spectroscopy: determination of double-bond quantity in unsaturated fatty acid compounds.

  NMR in biomedicine 20080501

• Arachidonic acid binds 14-3-3zeta, releases 14-3-3zeta from phosphorylated BAD and induces aggregation of 14-3-3zeta.

  Neurochemical research 20080501

• Arachidonic acid pathway activates multidrug resistance related protein in cultured human lung cells.

  Archives of toxicology 20080501

• Fenretinide prevents the development of osteoporosis in Cftr-KO mice.

  Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society 20080501

• Arachidonic acid metabolism in glucocorticoid-induced hypertension.

  Clinical and experimental pharmacology & physiology 20080501

• Lipoproteins inhibit platelet aggregation and arachidonic acid metabolism in experimental hypercholesterolaemia.

  Clinical and experimental pharmacology & physiology 20080501

• Imaging apomorphine stimulation of brain arachidonic acid signaling via D2-like receptors in unanesthetized rats.

  Psychopharmacology 20080501

• Ser515 phosphorylation-independent regulation of cytosolic phospholipase A2alpha (cPLA2alpha) by calmodulin-dependent protein kinase: possible interaction with catalytic domain A of cPLA2alpha.

  Cellular signalling 20080501

• Leukotriene synthesis is required for hedgehog-dependent neurite projection in neuralized embryoid bodies but not for motor neuron differentiation.

  Stem cells (Dayton, Ohio) 20080501

• Loss of prostaglandin E2 release from immortalized urothelial cells obtained from interstitial cystitis patient bladders.

  American journal of physiology. Renal physiology 20080501

• Deficient renal 20-HETE release in the diabetic rat is not the result of oxidative stress.

  American journal of physiology. Heart and circulatory physiology 20080501

• Fructose-induced structural and functional modifications of hemoglobin: implication for oxidative stress in diabetes mellitus.

  Biochimica et biophysica acta 20080501

• The arachidonic acid pathway and its role in prostate cancer development and progression.

  The Journal of urology 20080501

• Polyunsaturated fatty acids block platelet-activating factor-induced phosphatidylinositol 3 kinase/Akt-mediated apoptosis in intestinal epithelial cells.

  American journal of physiology. Gastrointestinal and liver physiology 20080501

• Altered release of cytochrome p450 metabolites of arachidonic acid in renovascular disease.

  Hypertension (Dallas, Tex. : 1979) 20080501

• Prostaglandin E2 modulates the expression of antimicrobial peptides in the fat body and midgut of Anopheles albimanus.

  Archives of insect biochemistry and physiology 20080501

• Cyclooxygenase and prostaglandin synthases in atherosclerosis: recent insights and future perspectives.

  Pharmacology & therapeutics 20080501

• Endocannabinoids and nutrition.

  Journal of neuroendocrinology 20080501

• Fish oil prevents essential fatty acid deficiency and enhances growth: clinical and biochemical implications.

  Metabolism: clinical and experimental 20080501

• Relationship between high platelet turnover and platelet function in high-risk patients with coronary artery disease on dual antiplatelet therapy.

  Thrombosis and haemostasis 20080501

• Meso-dihydroguaiaretic acid isolated from Saururus chinensis inhibits cyclooxygenase-2 and 5-lipoxygenase in mouse bone marrow-derived mast cells.

  Archives of pharmacal research 20080501

• Long-chain polyunsaturated fat supplementation in children with low docosahexaenoic acid intakes alters immune phenotypes compared with placebo.

  Journal of pediatric gastroenterology and nutrition 20080501

• Cyclooxygenases and the pathogenesis of chronic rhinosinusitis and nasal polyposis.

  Current allergy and asthma reports 20080501

• Inhibition of 15-lipoxygenase-catalysed oxygenation of arachidonic acid by substituted benzoic acids.

  Bioorganic & medicinal chemistry 20080415

• Costimulation of dectin-1 and DC-SIGN triggers the arachidonic acid cascade in human monocyte-derived dendritic cells.

  Journal of immunology (Baltimore, Md. : 1950) 20080415

• A rat air pouch model for evaluating the efficacy and selectivity of 5-lipoxygenase inhibitors.

  European journal of pharmacology 20080414

• Serotonin-induced activation of TRPV4-like current in rat intrapulmonary arterial smooth muscle cells.

  Cell calcium 20080401

• D-glucaro 1,4-lactone and resveratrol as antioxidants in blood platelets.

  Cell biology and toxicology 20080401

• Fatty acids differentially influence phosphatidylinositol 3-kinase signal transduction in endothelial cells: impact on adhesion and apoptosis.

  Atherosclerosis 20080401

• High vascular pressure-induced lung injury requires P450 epoxygenase-dependent activation of TRPV4.

  American journal of respiratory cell and molecular biology 20080401

• Coordinating cell proliferation and migration in the lens and cornea.

  Seminars in cell & developmental biology 20080401

• Standardization of light transmittance aggregometry for monitoring antiplatelet therapy: an adjustment for platelet count is not necessary.

  Journal of thrombosis and haemostasis : JTH 20080401

• cPLA2 phosphorylation at serine-515 and serine-505 is required for arachidonic acid release in vascular smooth muscle cells.

  Journal of lipid research 20080401

• Arachidonic acid activates Kir2.3 channels by enhancing channel-phosphatidyl-inositol 4,5-bisphosphate interactions.

  Molecular pharmacology 20080401

• Modulation of angiogenesis by omega-3 polyunsaturated fatty acids is mediated by cyclooxygenases.

  Blood 20080401

• Measurement of F2-isoprostanes, hydroxyeicosatetraenoic products, and oxysterols from a single plasma sample.

  Free radical biology & medicine 20080401

• Arachidonic acid in postshock mesenteric lymph induces pulmonary synthesis of leukotriene B4.

  Journal of applied physiology (Bethesda, Md. : 1985) 20080401

• Insulin resistance and impaired functional vasodilation in obese Zucker rats.

  American journal of physiology. Heart and circulatory physiology 20080401

• Prostaglandin E2 glycerol ester, an endogenous COX-2 metabolite of 2-arachidonoylglycerol, induces hyperalgesia and modulates NFkappaB activity.

  British journal of pharmacology 20080401

• Toxoplasma gondii induces prostaglandin E2 synthesis in macrophages via signal pathways for calcium-dependent arachidonic acid production and PKC-dependent induction of cyclooxygenase-2.

  Parasitology research 20080401

• Influence of dietary fatty acids on endocannabinoid and N-acylethanolamine levels in rat brain, liver and small intestine.

  Biochimica et biophysica acta 20080401

• SNPs of the FADS gene cluster are associated with polyunsaturated fatty acids in a cohort of patients with cardiovascular disease.

  Lipids 20080401

• On the importance of plasmalogen status in stimulated arachidonic acid release in the macrophage cell line RAW 264.7.

  Biochimica et biophysica acta 20080401

• Short-period hypoxia increases mouse embryonic stem cell proliferation through cooperation of arachidonic acid and PI3K/Akt signalling pathways.

  Cell proliferation 20080401

• Calcium-independent phospholipase A2 mediates proliferation of human promonocytic U937 cells.

  The FEBS journal 20080401

• The pathophysiologic role of cyclo-oxygenases in the eye.

  Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20080401

• Topical anti-inflammatory activity of Eugenia brasiliensis Lam. (Myrtaceae) leaves.

  The Journal of pharmacy and pharmacology 20080401

• Arachidonic acid-induced Ca2+ entry is involved in early steps of tumor angiogenesis.

  Molecular cancer research : MCR 20080401

• In vitro electron paramagnetic resonance characterization of free radicals: relevance to exercise-induced lipid peroxidation and implications of ascorbate prophylaxis.

  Free radical research 20080401

• Release of arachidonic acid induced by tumor necrosis factor-alpha in the presence of caspase inhibition: evidence for a cytosolic phospholipase A2alpha-independent pathway.

  Biochemical pharmacology 20080315

• Development and validation of a high-performance liquid chromatography-electrospray mass spectrometry method for the simultaneous determination of 23 eicosanoids.

  Journal of pharmaceutical and biomedical analysis 20080313

• Arachidonic acid and docosahexaenoic acid supplementation increases coronary flow velocity reserve in Japanese elderly individuals.

  Heart (British Cardiac Society) 20080301

• Arachidonic acid induces both Na+ and Ca2+ entry resulting in apoptosis.

  Journal of neurochemistry 20080301

• Antiinflammatory and neuroprotective actions of COX2 inhibitors in the injured brain.

  Brain, behavior, and immunity 20080301

• Flow cytometric assessment of platelet aspirin resistance using light scattering.

  Cytometry. Part B, Clinical cytometry 20080301

• Polyunsaturated fatty acids influence synaptojanin localization to regulate synaptic vesicle recycling.

  Molecular biology of the cell 20080301

• Role of calcium-independent phospholipase A2 in complement-mediated glomerular epithelial cell injury.

  American journal of physiology. Renal physiology 20080301

• Phospholipid actions on PGHS-1 and -2 cyclooxygenase kinetics.

  Prostaglandins & other lipid mediators 20080301

• Prevalence of platelet nonresponsiveness to aspirin in patients treated for secondary stroke prophylaxis and in patients with recurrent ischemic events.

  Journal of clinical pharmacology 20080301

• Suppressed catalytic efficiency of plasmin in the presence of long-chain fatty acids. Identification of kinetic parameters from continuous enzymatic assay with Monte Carlo simulation.

  The FEBS journal 20080301

• Arachidonic acid modulates the crosstalk between prostate carcinoma and bone stromal cells.

  Endocrine-related cancer 20080301

• Group IVA phospholipase A2-associated production of MMP-9 in macrophages and formation of atherosclerotic lesions.

  Biological & pharmaceutical bulletin 20080301

• Maternal and fetal brain contents of docosahexaenoic acid (DHA) and arachidonic acid (AA) at various essential fatty acid (EFA), DHA and AA dietary intakes during pregnancy in mice.

  Prostaglandins, leukotrienes, and essential fatty acids 20080301

• Dietary phosphatidylcholine improves maze-learning performance in adult mice.

  Journal of medicinal food 20080301

• Effect of long-chain n-3 polyunsaturated fatty acid on inflammation mediators during osteoblastogenesis.

  Journal of medicinal food 20080301

• Oxygenation of arachidonoyl lysophospholipids by lipoxygenases from soybean, porcine leukocyte, or rabbit reticulocyte.

  Journal of agricultural and food chemistry 20080227

• Local Ca2+ influx through Ca2+ release-activated Ca2+ (CRAC) channels stimulates production of an intracellular messenger and an intercellular pro-inflammatory signal.

  The Journal of biological chemistry 20080222

• Leukotrienes.

  The New England journal of medicine 20080214

• Activation of cytosolic phospholipase A2alpha through nitric oxide-induced S-nitrosylation. Involvement of inducible nitric-oxide synthase and cyclooxygenase-2.

  The Journal of biological chemistry 20080208

• Human platelet 12-lipoxygenase, new findings about its activity, membrane binding and low-resolution structure.

  Journal of molecular biology 20080208

• Co-supplementation of healthy women with fish oil and evening primrose oil increases plasma docosahexaenoic acid, gamma-linolenic acid and dihomo-gamma-linolenic acid levels without reducing arachidonic acid concentrations.

  The British journal of nutrition 20080201

• Glucose homeostasis, insulin secretion, and islet phospholipids in mice that overexpress iPLA2beta in pancreatic beta-cells and in iPLA2beta-null mice.

  American journal of physiology. Endocrinology and metabolism 20080201

• Synergistic toxicity induced by prolonged glutathione depletion and inhibition of nuclear factor-kappaB signaling in liver cells.

  Toxicology in vitro : an international journal published in association with BIBRA 20080201

• Restorative proctocolectomy for ulcerative colitis: impact on lipid metabolism and adipose tissue and serum fatty acids.

  Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20080201

• Mefenamic acid bi-directionally modulates the transient outward K+ current in rat cerebellar granule cells.

  Toxicology and applied pharmacology 20080201

• Cytosolic phospholipase A2 and arachidonic acid metabolites modulate ventilator-induced permeability increases in isolated mouse lungs.

  Journal of applied physiology (Bethesda, Md. : 1985) 20080201

• Endothelium-derived hyperpolarizing factor in preeclampsia: heterogeneous contribution, mechanisms, and morphological prerequisites.

  American journal of physiology. Regulatory, integrative and comparative physiology 20080201

• Licofelone, a dual COX/5-LOX inhibitor, induces apoptosis in HCA-7 colon cancer cells through the mitochondrial pathway independently from its ability to affect the arachidonic acid cascade.

  Carcinogenesis 20080201

• Age-related decrease in 15-lipoxygenase contributes to reduced vasorelaxation in rabbit aorta.

  American journal of physiology. Heart and circulatory physiology 20080201

• Capturing proteins that bind polyunsaturated fatty acids: demonstration using arachidonic acid and eicosanoids.

  Lipids 20080201

• Influence of pancreatic status and sex on polyunsaturated fatty acid profiles in cystic fibrosis.

  Clinical chemistry 20080201

• Pathways of arachidonic acid peroxyl radical reactions and product formation with guanine radicals.

  Chemical research in toxicology 20080201

• Conjugated linoleic acid increases intracellular ROS synthesis and oxygenation of arachidonic acid in macrophages.

  Nutrition (Burbank, Los Angeles County, Calif.) 20080201

• Endothelial 15-lipoxygenase-1 overexpression increases acetylcholine-induced hypotension and vasorelaxation in rabbits.

  Hypertension (Dallas, Tex. : 1979) 20080201

• Cyclooxygenase (COX) and 5-lipoxygenase (5-LOX) selectivity of COX inhibitors.

  Prostaglandins, leukotrienes, and essential fatty acids 20080201

• Modulation of cardiac and hepatic cytochrome P450 enzymes during heart failure.

  Current drug metabolism 20080201

• Antiplatelet aggregation coumarins from the leaves of Murraya omphalocarpa.

  Molecules (Basel, Switzerland) 20080121

• Identification and functional analysis of cyclooxygenase-1 as a molecular target of boswellic acids.

  Biochemical pharmacology 20080115

• Neurofurans, novel indices of oxidant stress derived from docosahexaenoic acid.

  The Journal of biological chemistry 20080104

• A novel lipid binding site formed by the MAP kinase insert in p38 alpha.

  Journal of molecular biology 20080104

• Arachidonic acid and glucose uptake by freshly isolated human adipocytes.

  Cell biochemistry and function 20080101

• Soy-based infant formula supplemented with DHA and ARA supports growth and increases circulating levels of these fatty acids in infants.

  Lipids 20080101

• Arachidonic acid as a retrograde signal controlling growth and dynamics of retinotectal arbors.

  Developmental neurobiology 20080101

• Effects of cyclooxygenase inhibition on canine coronary artery blood flow and thrombosis.

  American journal of physiology. Heart and circulatory physiology 20080101

• Predominant basal directional release of thromboxane, but not prostacyclin, by placental trophoblasts from normal and preeclamptic pregnancies.

  Placenta 20080101

• Roles of PKA, PI3K, and cPLA2 in the NO-mediated negative inotropic effect of beta2-adrenoceptor agonists in guinea pig right papillary muscles.

  American journal of physiology. Cell physiology 20080101

• Chronic N-methyl-D-aspartate administration increases the turnover of arachidonic acid within brain phospholipids of the unanesthetized rat.

  Journal of lipid research 20080101

• Compartmentalization of endocannabinoids into lipid rafts in a dorsal root ganglion cell line.

  British journal of pharmacology 20080101

• Both Orai1 and Orai3 are essential components of the arachidonate-regulated Ca2+-selective (ARC) channels.

  The Journal of physiology 20080101

• Opposite changes in predominantly docosahexaenoic acid (DHA) in cerebrospinal fluid and red blood cells from never-medicated first-episode psychotic patients.

  Schizophrenia research 20080101

• Folic acid and polyunsaturated fatty acids improve cognitive function and prevent depression, dementia, and Alzheimer's disease--but how and why?

  Prostaglandins, leukotrienes, and essential fatty acids 20080101

• Rationale for adjuvant fatty acid therapy to prevent radiotherapy failure and tumor recurrence during early laryngeal squamous cell carcinoma.

  Prostaglandins, leukotrienes, and essential fatty acids 20080101

• Stearic acid potently modulates the activity of cyclooxygenase-1, but not cyclooxygenase-2, in the form of its CoA ester.

  Prostaglandins, leukotrienes, and essential fatty acids 20080101

• Effects of generated trans-arachidonic acids on retinal capillary during nitrative stress in diabetic rats.

  Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 20080101

• Variable responsiveness to clopidogrel and aspirin among patients with acute coronary syndrome as assessed by platelet function tests.

  Thrombosis research 20080101

• Nutritionally essential fatty acids and biologically indispensable cyclooxygenases.

  Trends in biochemical sciences 20080101

• In vitro antiplatelet activity of flavonoids from Leuzea carthamoides.

  Drug and chemical toxicology 20080101

• Population pharmacodynamic modelling of aspirin- and Ibuprofen-induced inhibition of platelet aggregation in healthy subjects.

  Clinical pharmacokinetics 20080101

• Prolactin-releasing peptide.

  Results and problems in cell differentiation 20080101

• Vascular cytochrome p450 enzymes: physiology and pathophysiology.

  Trends in cardiovascular medicine 20080101

• Antiplatelet activity of epigallocatechin gallate is mediated by the inhibition of PLCgamma2 phosphorylation, elevation of PGD2 production, and maintaining calcium-ATPase activity.

  Journal of cardiovascular pharmacology 20080101

• Prenatal long-chain polyunsaturated fatty acid status: the importance of a balanced intake of docosahexaenoic acid and arachidonic acid.

  Journal of perinatal medicine 20080101

• Comment on 'hyperresponsiveness of platelets in ischemic stroke' by Fateh-Moghadam et al.

  Thrombosis and haemostasis 20080101

• A common polymorphism G-50T in cytochrome P450 2J2 gene is associated with increased risk of essential hypertension in a Russian population.

  Disease markers 20080101

• Linoleic acid metabolite levels and transepidermal water loss in children with atopic dermatitis.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20080101

• 15,16-dihydrotanshinone I, a major component from Salvia miltiorrhiza Bunge (Dansham), inhibits rabbit platelet aggregation by suppressing intracellular calcium mobilization.

  Archives of pharmacal research 20080101

• Inflammatory responses after endothelin B (ETB) receptor activation in human monocytes: new evidence for beneficial anti-inflammatory potency of ETB-receptor antagonism.

  Pulmonary pharmacology & therapeutics 20080101

• Biochemistry and physiology of mammalian secreted phospholipases A2.

  Annual review of biochemistry 20080101

• Pivotal role of arachidonic acid in the regulation of neuronal nitric oxide synthase activity and inducible nitric oxide synthase expression in activated astrocytes.

  Methods in enzymology 20080101

• Serum concentrations of fatty acids and colorectal adenoma risk: a case-control study in Japan.

  Asian Pacific journal of cancer prevention : APJCP 20080101

• Aspirin non-responsiveness in Korean subjects on dual anti-platelet treatment determined by two different platelet function assays.

  Annals of clinical and laboratory science 20080101

• [Membrane platelet fatty acids: biochemical characterisation of the ischemic cardiovascular disease, characteristics of the paediatric age, through an artificial neural network interpretation].

  La Pediatria medica e chirurgica : Medical and surgical pediatrics 20080101

• The arachidonate-dependent survival signaling preventing toxicity in monocytes/macrophages exposed to peroxynitrite.

  Methods in enzymology 20080101

• [Ankylosing Spondylitis and convenient nutrition].

  Wiener medizinische Wochenschrift (1946) 20080101

• Prenatal supply of docosahexaenoic acid (DHA): should we be worried?

  Journal of perinatal medicine 20080101

• Effects of 3-aminopyridine-induced seizures on platelet eicosanoid synthesis.

  Pharmacological reports : PR 20080101

• Monitoring aspirin therapy with the Platelet Function Analyzer-100.

  Scandinavian journal of clinical and laboratory investigation 20080101

• [Activation of elicitor defensive properties by systemic signal molecules during the interaction between potato and Phytophthora].

  Prikladnaia biokhimiia i mikrobiologiia 20080101

• Protective effect of eicosapentaenoic acid on palmitate-induced apoptosis in neonatal cardiomyocytes.

  Biochimica et biophysica acta 20080101

• Phospholipase A2 regulation of bovine endometrial (BEND) cell prostaglandin production.

  Reproductive biology and endocrinology : RB&E 20080101

• Involvement of cPLA2 inhibition in dexamethasone-induced thymocyte apoptosis.

  International journal of immunopathology and pharmacology 20080101

• The relationship between the fatty acid composition of immune cells and their function.

  Prostaglandins, leukotrienes, and essential fatty acids 20080101

• Impact of linoleic acid intake on arachidonic acid formation and eicosanoid biosynthesis in humans.

  Prostaglandins, leukotrienes, and essential fatty acids 20080101

• Brain arachidonic and docosahexaenoic acid cascades are selectively altered by drugs, diet and disease.

  Prostaglandins, leukotrienes, and essential fatty acids 20080101

• The health implications of changing linoleic acid intakes.

  Prostaglandins, leukotrienes, and essential fatty acids 20080101

• Effects of different dietary fatty acids on the fatty acid compositions and the expression of lipid metabolic-related genes in mammary tumor tissues of rats.

  Nutrition and cancer 20080101

• Total lipids and fatty acids composition of the coastal and the deep-sea common octopus (Octopus vulgaris) populations: a comparative study.

  Nutrition and health 20080101

• Effect of Iron Therapy on Platelet Function among Iron-Deficient Women with Unexplained Menorrhagia.

  Pathophysiology of haemostasis and thrombosis 20080101

• Arachidonic acid and prostaglandin E2 influence human osteoblast (MG63) response to titanium surface roughness.

  The Journal of oral implantology 20080101

• Endomorphin-1 inhibits the activation and the development of a hyporesponsive-like phenotype in lipopolysaccharide- stimulated THP-1 monocytes.

  International journal of immunopathology and pharmacology 20080101

• Elicitor-induced reparation of wounded potato tubers.

  Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections 20080101

• Pharmacological nature of nicotine-induced contraction in the rat basilar artery: involvement of arachidonic acid metabolites.

  European journal of pharmacology 20071222

• Anti-inflammatory lipid mediator 15d-PGJ2 inhibits translation through inactivation of eIF4A.

  The EMBO journal 20071212

• Secretory phospholipase A2-alpha from Arabidopsis thaliana: functional parameters and substrate preference.

  Chemistry and physics of lipids 20071201

• NADPH oxidase deficiency results in reduced alveolar macrophage 5-lipoxygenase expression and decreased leukotriene synthesis.

  Journal of leukocyte biology 20071201

• Sonic hedgehog induces transcription-independent cytoskeletal rearrangement and migration regulated by arachidonate metabolites.

  Cellular signalling 20071201

• Lipoxygenase metabolism: roles in tumor progression and survival.

  Cancer metastasis reviews 20071201

• Mitochondrial P450-dependent arachidonic acid metabolism by TCDD-induced hepatic CYP1A5; conversion of EETs to DHETs by mitochondrial soluble epoxide hydrolase.

  Archives of biochemistry and biophysics 20071201

• High omega-6 and low omega-3 fatty acids are associated with depressive symptoms and neuroticism.

  Psychosomatic medicine 20071201

• Cytochrome P450 2C19 loss-of-function polymorphism, but not CYP3A4 IVS10 + 12G/A and P2Y12 T744C polymorphisms, is associated with response variability to dual antiplatelet treatment in high-risk vascular patients.

  Pharmacogenetics and genomics 20071201

• Expression of thermosensitive two-pore domain K+ channels in human keratinocytes cell line HaCaT cells.

  Experimental dermatology 20071201

• Why fish oils may not always be adequate treatments for depression or other inflammatory illnesses: docosahexaenoic acid, an omega-3 polyunsaturated fatty acid, induces a Th-1-like immune response.

  Neuro endocrinology letters 20071201

• Tetrahydrofurandiol stimulation of phospholipase A2, lipoxygenase, and cyclooxygenase gene expression and MCF-7 human breast cancer cell proliferation.

  Environmental health perspectives 20071201

• Roles of epoxyeicosatrienoic acids in vascular regulation and cardiac preconditioning.

  Journal of cardiovascular pharmacology 20071201

• Arachidonic Acid metabolites in the cardiovascular system: the role of lipoxygenase isoforms in atherogenesis with particular emphasis on vascular remodeling.

  Journal of cardiovascular pharmacology 20071201

• Beta-carotene and arachidonic acid induced DNA methylation and the regulation of pro-chemotactic activity of endothelial cells and its progenitors.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20071201

• Arachidonic acid is a chemoattractant for Dictyostelium discoideum cells.

  Journal of biosciences 20071201

• [The role of NADPH oxidase in superoxide anion generation in rabbit lens epithelial cells].

  Yan ke xue bao = Eye science 20071201

• [What is new about nonsteroidal antiinflamatory drugs?].

  Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20071201

• The confluence-dependent interaction of cytosolic phospholipase A2-alpha with annexin A1 regulates endothelial cell prostaglandin E2 generation.

  The Journal of biological chemistry 20071123

• Jak2 dampens the induction by IL-1beta of prostaglandin endoperoxide H synthase 2 expression in human orbital fibroblasts: evidence for divergent influence on the prostaglandin E2 biosynthetic pathway.

  Journal of immunology (Baltimore, Md. : 1950) 20071115

• Oxidation of 2-Cys-peroxiredoxins by arachidonic acid peroxide metabolites of lipoxygenases and cyclooxygenase-2.

  The Journal of biological chemistry 20071109

• Synergistic effect of cytochrome P450 epoxygenase CYP2J2*7 polymorphism with smoking on the onset of premature myocardial infarction.

  Atherosclerosis 20071101

• Dose-dependent coronary artery intimal thickening after local delivery of the anti-oxidant tetradecylthioacetic acid from stents.

  Atherosclerosis 20071101

• Is metabolic syndrome X a disorder of the brain with the initiation of low-grade systemic inflammatory events during the perinatal period?

  The Journal of nutritional biochemistry 20071101

• Residual platelet reactivity is associated with clinical and laboratory characteristics in patients with ischemic heart disease undergoing PCI on dual antiplatelet therapy.

  Atherosclerosis 20071101

• Flurbiprofen, a cyclooxygenase inhibitor, reduces the brain arachidonic acid signal in response to the cholinergic muscarinic agonist, arecoline, in awake rats.

  Neurochemical research 20071101

• Assessment of skin absorption and irritation potential of arachidonic acid and glyceryl arachidonate using in vitro diffusion cell techniques.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20071101

• Randomized clinical trial of the effects of perioperative use of immune-enhancing enteral formula on metabolic and immunological status in patients undergoing esophagectomy.

  World journal of surgery 20071101

• Early release of arachidonic acid prevents an otherwise immediate formation of toxic levels of peroxynitrite in astrocytes stimulated with lipopolysaccharide/interferon-gamma.

  Journal of neurochemistry 20071101

• Alpha2-adrenergic receptors activate cyclic AMP-response element-binding protein through arachidonic acid metabolism and protein kinase A in a subtype-specific manner.

  Journal of neurochemistry 20071101

• Human enteric microsomal CYP4F enzymes O-demethylate the antiparasitic prodrug pafuramidine.

  Drug metabolism and disposition: the biological fate of chemicals 20071101

• Bioequivalence of Docosahexaenoic acid from different algal oils in capsules and in a DHA-fortified food.

  Lipids 20071101

• Neonatal dietary supplementation of arachidonic acid increases prostaglandin levels in adipose tissue but does not promote fat mass development in guinea pigs.

  American journal of physiology. Regulatory, integrative and comparative physiology 20071101

• Inhibition of L-type Ca2+ channel current and negative inotropy induced by arachidonic acid in adult rat ventricular myocytes.

  American journal of physiology. Cell physiology 20071101

• Neuroprotection and free radical scavenging effects of Osmanthus fragrans.

  Journal of biomedical science 20071101

• Detrimental effects of post-treatment with fatty acids on brain injury in ischemic rats.

  Neurotoxicology 20071101

• Inhibition of 2-arachidonoylglycerol catabolism modulates vasoconstriction of rat middle cerebral artery by the thromboxane mimetic, U-46619.

  British journal of pharmacology 20071101

• Cyclooxygenase-2-mediated metabolism of arachidonic acid to 15-oxo-eicosatetraenoic acid by rat intestinal epithelial cells.

  Chemical research in toxicology 20071101

• Arachidonic acid signaling is involved in the mechanism of imidazoline-induced KATP channel-independent stimulation of insulin secretion.

  Cellular and molecular life sciences : CMLS 20071101

• Plasma free polyunsaturated fatty acid levels are associated with symptom severity in acute mania.

  Bipolar disorders 20071101

• Trans fatty acids in partially hydrogenated soybean oil inhibit prostacyclin release by endothelial cells in presence of high level of linoleic acid.

  Prostaglandins & other lipid mediators 20071101

• Effect of luteinizing hormone (LH), pregnancy-specific protein B (PSPB), or arachidonic acid (AA) on secretion of progesterone and prostaglandins (PG) E (PGE; PGE(1) and PGE(2)) and F(2alpha) (PGF(2alpha)) by ovine corpora lutea of the estrous cycle or pregnancy in vitro.

  Prostaglandins & other lipid mediators 20071101

• [Hypercapnia- and trans-arachidonic acid-induced retinal microvascular degeneration: implications in the genesis of retinopathy of prematurity].

  Medecine sciences : M/S 20071101

• Arachidonic acid metabolites in the cardiovascular system.

  Journal of cardiovascular pharmacology 20071101

• [Prostaglandin and nociceptin/orphanin FQ].

  Masui. The Japanese journal of anesthesiology 20071101

• The properties of aminophylline.

  Emergency nurse : the journal of the RCN Accident and Emergency Nursing Association 20071101

• Adenosine inhibits the release of arachidonic acid and its metabolites (AAM) in activated human peripheral mononuclear cells.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20071101

• [Study on composing mechanism by effect of disassembled compositions of Yiqi Huoxue decoction on platelet aggregation of health adults].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20071101

• Structural insight into the dual ligand specificity and mode of high density lipoprotein association of apolipoprotein D.

  The Journal of biological chemistry 20071019

• Chronic carbamazepine administration reduces N-methyl-D-aspartate receptor-initiated signaling via arachidonic acid in rat brain.

  Biological psychiatry 20071015

• Chemoprevention of familial adenomatous polyposis by natural dietary compounds sulforaphane and dibenzoylmethane alone and in combination in ApcMin/+ mouse.

  Cancer research 20071015

• Identification of novel autoxidation products of the omega-3 fatty acid eicosapentaenoic acid in vitro and in vivo.

  The Journal of biological chemistry 20071012

• Calcium oscillations induced by ATP in human umbilical cord smooth muscle cells.

  Journal of cellular physiology 20071001

• Spore germination in Mortierella alpina is associated with a transient depletion of arachidonic acid and induction of fatty acid desaturase gene expression.

  Archives of microbiology 20071001

• The lipid connection-regulation of voltage-gated Ca(2+) channels by phosphoinositides.

  Pflugers Archiv : European journal of physiology 20071001

• Docosahexaenoic acid enhances iron uptake by modulating iron transporters and accelerates apoptotic death in PC12 cells.

  Neurochemical research 20071001

• Activatory properties of lysophosphatidic acid on human THP-1 cells.

  Inflammation 20071001

• Roles of brain phosphatidylinositol-specific phospholipase C and diacylglycerol lipase in centrally administered histamine-induced adrenomedullary outflow in rats.

  European journal of pharmacology 20071001

• Antipsoriatic effects of avarol-3'-thiosalicylate are mediated by inhibition of TNF-alpha generation and NF-kappaB activation in mouse skin.

  British journal of pharmacology 20071001

• Pharmacological characterization of a novel nonpeptide antagonist for formyl peptide receptor-like 1.

  Molecular pharmacology 20071001

• Delta5 desaturase mRNA levels are increased by simvastatin via SREBP-1 at early stages, not via PPARalpha, in THP-1 cells.

  European journal of pharmacology 20071001

• Expression and activity of cyclooxygenase isoforms in skeletal muscles and myocardium of humans and rodents.

  Journal of applied physiology (Bethesda, Md. : 1985) 20071001

• In vivo imaging of disturbed pre- and post-synaptic dopaminergic signaling via arachidonic acid in a rat model of Parkinson's disease.

  NeuroImage 20071001

• The molecular mechanism of the inhibition by licofelone of the biosynthesis of 5-lipoxygenase products.

  British journal of pharmacology 20071001

• Comparative analysis of peritoneum and tumor eicosanoids and pathways in advanced ovarian cancer.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20071001

• [NSAID and its effect on prostaglandin].

  Nihon rinsho. Japanese journal of clinical medicine 20071001

• Antiplatelet effect of NQ12: a possible mechanism through the arachidonic acid cascade.

  Journal of pharmacological sciences 20071001

• Genetic variation in the cytochrome P450 epoxygenase pathway and cardiovascular disease risk.

  Pharmacogenomics 20071001

• Polyunsaturated fatty acids in cystic fibrosis are related to nutrition and clinical expression of the disease.

  Journal of pediatric gastroenterology and nutrition 20071001

• [Unelucidated biological phenomena].

  Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 20071001

• Effect of inhibitors of arachidonic acid conversion in platelets on thrombin-fibrinogen interaction and thrombin tolerance.

  Bulletin of experimental biology and medicine 20071001

• Adenovirus type 5 exerts multiple effects on the expression and activity of cytosolic phospholipase A2, cyclooxygenase-2, and prostaglandin synthesis.

  Journal of immunology (Baltimore, Md. : 1950) 20070915

• Attenuated free cholesterol loading-induced apoptosis but preserved phospholipid composition of peritoneal macrophages from mice that do not express group VIA phospholipase A2.

  The Journal of biological chemistry 20070914

• Implication of cytosolic phospholipase A2 (cPLA2) in the regulation of human synoviocyte NADPH oxidase (Nox2) activity.

  Life sciences 20070908

• Probing phospholipase a(2) with fluorescent phospholipid substrates.

  Chembiochem : a European journal of chemical biology 20070903

• Antiplatelet activity of hesperetin, a bioflavonoid, is mainly mediated by inhibition of PLC-gamma2 phosphorylation and cyclooxygenase-1 activity.

  Atherosclerosis 20070901

• Altered spinal arachidonic acid turnover after peripheral nerve injury regulates regional glutamate concentration and neuropathic pain behaviors in rats.

  Pain 20070901

• Diverse roles of 2-arachidonoylglycerol in invasion of prostate carcinoma cells: Location, hydrolysis and 12-lipoxygenase metabolism.

  International journal of cancer 20070901

• Effects of arachidonate-enriched triacylglycerol supplementation on serum fatty acids and platelet aggregation in healthy male subjects with a fish diet.

  The British journal of nutrition 20070901

• Activation of cPLA2 and sPLA2 in astrocytes exposed to simulated ischemia in vitro.

  Cell biology international 20070901

• 12-Lipoxygenase-derived eicosanoids protect against myocardial ischemia/reperfusion injury via activation of neuronal TRPV1.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20070901

• Chronic lamotrigine does not alter the turnover of arachidonic acid within brain phospholipids of the unanesthetized rat: implications for the treatment of bipolar disorder.

  Psychopharmacology 20070901

• Protein kinase C-beta and -delta isoenzymes promote arachidonic acid production and proliferation of MonoMac-6 cells.

  Journal of molecular medicine (Berlin, Germany) 20070901

• Chronic NMDA administration to rats up-regulates frontal cortex cytosolic phospholipase A2 and its transcription factor, activator protein-2.

  Journal of neurochemistry 20070901

• Prostaglandin synthesis in rat brain astrocytes is under the control of the n-3 docosahexaenoic acid, released by group VIB calcium-independent phospholipase A2.

  Journal of neurochemistry 20070901

• Nutrigenomics applied to an animal model of Inflammatory Bowel Diseases: transcriptomic analysis of the effects of eicosapentaenoic acid- and arachidonic acid-enriched diets.

  Mutation research 20070901

• A key role for diacylglycerol lipase-alpha in metabotropic glutamate receptor-dependent endocannabinoid mobilization.

  Molecular pharmacology 20070901

• Roles of the cytochrome P450 arachidonic acid monooxygenases in the control of systemic blood pressure and experimental hypertension.

  Kidney international 20070901

• Altered mechanisms of endothelium-dependent dilation in skeletal muscle arterioles with genetic hypercholesterolemia.

  American journal of physiology. Regulatory, integrative and comparative physiology 20070901

• Hydroxychavicol, a novel betel leaf component, inhibits platelet aggregation by suppression of cyclooxygenase, thromboxane production and calcium mobilization.

  British journal of pharmacology 20070901

• Characterization of prostaglandin E2 generation through the cyclooxygenase (COX)-2 pathway in human neutrophils.

  Biochimica et biophysica acta 20070901

• Regulation of ion transport and blood pressure by cytochrome p450 monooxygenases.

  Current opinion in nephrology and hypertension 20070901

• Dietary arachidonic acid: harmful, harmless or helpful?

  The British journal of nutrition 20070901

• Association of n-6 long-chain polyunsaturated fatty acids to -866 G/A genotypes of the human uncoupling protein 2 gene in obese children.

  Acta paediatrica (Oslo, Norway : 1992) 20070901

• Platelet function measured by VerifyNow identifies generalized high platelet reactivity in aspirin treated patients.

  Platelets 20070901

• Platelet activation increases with the severity of peripheral arterial disease: implications for clinical management.

  Journal of vascular surgery 20070901

• Molecular oxygen (a substrate of the cyclooxygenase reaction) in the kinetic mechanism of the bifunctional enzyme prostaglandin-H-synthase.

  Biochemistry. Biokhimiia 20070901

• Oxidative stress in preterm infants fed a formula containing long-chain polyunsaturated fatty acids (LCPUFA).

  American journal of perinatology 20070901

• Group VIA phospholipase A2 (iPLA2beta) participates in angiotensin II-induced transcriptional up-regulation of regulator of g-protein signaling-2 in vascular smooth muscle cells.

  The Journal of biological chemistry 20070831

• Chronic administration of docosahexaenoic acid or eicosapentaenoic acid, but not arachidonic acid, alone or in combination with uridine, increases brain phosphatide and synaptic protein levels in gerbils.

  Neuroscience 20070824

• Akt activation by arachidonic acid metabolism occurs via oxidation and inactivation of PTEN tumor suppressor.

  Oncogene 20070823

• An arachidonic acid generation/export system involved in the regulation of cholesterol transport in mitochondria of steroidogenic cells.

  FEBS letters 20070821

• The influence of interleukin-1beta on oxytocin signalling in primary cells of human decidua.

  Regulatory peptides 20070816

• Peroxisome-proliferator-activated receptors and the control of levels of prostaglandin-endoperoxide synthase 2 by arachidonic acid in the bovine uterus.

  The Biochemical journal 20070815

• 13-Oxo-ODE is an endogenous ligand for PPARgamma in human colonic epithelial cells.

  Biochemical pharmacology 20070815

• Enzymes and receptors of prostaglandin pathways with arachidonic acid-derived versus eicosapentaenoic acid-derived substrates and products.

  The Journal of biological chemistry 20070803

• Arachidonic acid preserves hippocampal neuron membrane fluidity in senescent rats.

  Neurobiology of aging 20070801

• Role of TRPV receptors in respiratory diseases.

  Biochimica et biophysica acta 20070801

• STIM1 and the noncapacitative ARC channels.

  Cell calcium 20070801

• Arachidonic acid metabolism in brain physiology and pathology: lessons from genetically altered mouse models.

  Journal of neurochemistry 20070801

• Heat shock preconditioning induces protein carbonylation and alters antioxidant protection in superficially injured guinea pig gastric mucosa in vitro.

  Digestive diseases and sciences 20070801

• Dipyrone elicits substantial inhibition of peripheral cyclooxygenases in humans: new insights into the pharmacology of an old analgesic.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20070801

• Steroid-producing cells regulate arterial tone of adrenal cortical arteries.

  Endocrinology 20070801

• Enhanced vasoconstrictor prostanoid production by sinusoidal endothelial cells increases portal perfusion pressure in cirrhotic rat livers.

  Journal of hepatology 20070801

• Human pharmacology of naproxen sodium.

  The Journal of pharmacology and experimental therapeutics 20070801

• Chronic lithium administration attenuates up-regulated brain arachidonic acid metabolism in a rat model of neuroinflammation.

  Journal of neurochemistry 20070801

• Adipose tissue arachidonic acid and the metabolic syndrome in Costa Rican adults.

  Clinical nutrition (Edinburgh, Scotland) 20070801

• Role of endogenous CYP450 metabolites of arachidonic acid in maintaining the glomerular protein permeability barrier.

  American journal of physiology. Renal physiology 20070801

• Stimulation of rat erythrocyte P2X7 receptor induces the release of epoxyeicosatrienoic acids.

  British journal of pharmacology 20070801

• Decrease in PIP(2) channel interactions is the final common mechanism involved in PKC- and arachidonic acid-mediated inhibitions of GABA(B)-activated K+ current.

  The Journal of physiology 20070801

• Characteristics of obese children with low content of arachidonic acid in plasma lipids.

  Pediatrics international : official journal of the Japan Pediatric Society 20070801

• Arachidonic acid but not eicosapentaenoic acid (EPA) and oleic acid activates NF-kappaB and elevates ICAM-1 expression in Caco-2 cells.

  Lipids 20070801

• Biosynthesis and metabolism of leukotrienes.

  The Biochemical journal 20070801

• Astrocytic calcium signaling: the information currency coupling neuronal activity to the cerebral microcirculation.

  Trends in cardiovascular medicine 20070801

• Linoleic and arachidonic acid in perinatal asphyxia and prematurity.

  The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 20070801

• [Modified platelet aggregation test in patients on ASA and/or clopidogrel].

  Hamostaseologie 20070801

• Metabolism of arachidonic acid in sheep uterus: in vitro studies.

  Indian journal of biochemistry & biophysics 20070801

• A complex mechanism for inducer mediated tau polymerization.

  Biochemistry 20070731

• Crystal structure of inhibitor-bound human 5-lipoxygenase-activating protein.

  Science (New York, N.Y.) 20070727

• Effects of naturally occurring dihydroflavonols from Inula viscosa on inflammation and enzymes involved in the arachidonic acid metabolism.

  Life sciences 20070719

• Group V secretory PLA2 regulates TLR2-dependent eicosanoid generation in mouse mast cells through amplification of ERK and cPLA2alpha activation.

  Blood 20070715

• Lanthanum suppresses arachidonic acid-induced cell death and mitochondrial depolarization in PC12 cells.

  European journal of pharmacology 20070712

• ACh-induced relaxations of rabbit small mesenteric arteries: role of arachidonic acid metabolites and K+.

  American journal of physiology. Heart and circulatory physiology 20070701

• Mechanism of attenuation of angiotensin-II-induced protein degradation by insulin-like growth factor-I (IGF-I).

  Cellular signalling 20070701

• Interactions between neural membrane glycerophospholipid and sphingolipid mediators: a recipe for neural cell survival or suicide.

  Journal of neuroscience research 20070701

• Flufenamic acid bi-directionally modulates the transient outward K(+) current in rat cerebellar granule cells.

  The Journal of pharmacology and experimental therapeutics 20070701

• Signalling within the neurovascular unit in the mammalian retina.

  Experimental physiology 20070701

• Promoter polymorphism G-50T of a human CYP2J2 epoxygenase gene is associated with common susceptibility to asthma.

  Chest 20070701

• Molecular basis for prostaglandin production in hosts and parasites.

  Trends in parasitology 20070701

• Activation and inactivation of the volume-sensitive taurine leak pathway in NIH3T3 fibroblasts and Ehrlich Lettre ascites cells.

  American journal of physiology. Cell physiology 20070701

• Comparison of different methods to evaluate the effect of aspirin on platelet function in high-risk patients with ischemic heart disease receiving dual antiplatelet treatment.

  American journal of clinical pathology 20070701

• Omega-6 and omega-3 fatty acids predict accelerated decline of peripheral nerve function in older persons.

  European journal of neurology 20070701

• Imbalance between leukotriene synthesis and catabolism contributes to the pathogenesis of allergic diseases.

  Medicinal chemistry (Shariqah (United Arab Emirates)) 20070701

• Effect of hemoglobin vesicle, a cellular-type artificial oxygen carrier, on middle cerebral artery occlusion- and arachidonic acid-induced stroke models in rats.

  Neuroscience letters 20070627

• Evaluation of dose-related effects of aspirin on platelet function: results from the Aspirin-Induced Platelet Effect (ASPECT) study.

  Circulation 20070626

• The anti-inflammatory effects of selenium are mediated through 15-deoxy-Delta12,14-prostaglandin J2 in macrophages.

  The Journal of biological chemistry 20070622

• Functional polymorphism in human CYP4F2 decreases 20-HETE production.

  Physiological genomics 20070619

• 2,2',4,4'-Tetrachlorobiphenyl upregulates cyclooxygenase-2 in HL-60 cells via p38 mitogen-activated protein kinase and NF-kappaB.

  Toxicology and applied pharmacology 20070615

• TNF-alpha inhibits macrophage clearance of apoptotic cells via cytosolic phospholipase A2 and oxidant-dependent mechanisms.

  Journal of immunology (Baltimore, Md. : 1950) 20070615

• The anti-pruritic efficacy of TS-022, a prostanoid DP1 receptor agonist, is dependent on the endogenous prostaglandin D2 level in the skin of NC/Nga mice.

  European journal of pharmacology 20070614

• Adrenal adrenaline- and noradrenaline-containing cells and celiac sympathetic ganglia are differentially controlled by centrally administered corticotropin-releasing factor and arginine-vasopressin in rats.

  European journal of pharmacology 20070614

• Anti-inflammatory activity of Dalbergia lanceolaria bark ethanol extract in mice and rats.

  Journal of ethnopharmacology 20070613

• Effects of new combinative antioxidant FeAOX-6 and alpha-tocotrienol on macrophage atherogenesis-related functions.

  Vascular pharmacology 20070601

• Functional selectivity of hallucinogenic phenethylamine and phenylisopropylamine derivatives at human 5-hydroxytryptamine (5-HT)2A and 5-HT2C receptors.

  The Journal of pharmacology and experimental therapeutics 20070601

• Feedback activation of ferrous 5-lipoxygenase during leukotriene synthesis by coexisting linoleic acid.

  Journal of lipid research 20070601

• Rapid modulation of micro-opioid receptor signaling in primary sensory neurons.

  The Journal of pharmacology and experimental therapeutics 20070601

• Anti-inflammatory activity of a potent, selective leukotriene A4 hydrolase inhibitor in comparison with the 5-lipoxygenase inhibitor zileuton.

  The Journal of pharmacology and experimental therapeutics 20070601

• Molecular mechanism of arachidonic acid inhibition of the CFTR chloride channel.

  European journal of pharmacology 20070601

• Airway nitric oxide in patients with cystic fibrosis is associated with pancreatic function, Pseudomonas infection, and polyunsaturated fatty acids.

  Chest 20070601

• A Bax/Bak-independent mechanism of cytochrome c release.

  The Journal of biological chemistry 20070601

• Comprehensive analysis of the effects of ordinary nutrients on hepatitis C virus RNA replication in cell culture.

  Antimicrobial agents and chemotherapy 20070601

• Role of prostaglandins on mechanical scratching-induced cutaneous barrier disruption in mice.

  Experimental dermatology 20070601

• Aspirin resistance among long-term aspirin users after carotid endarterectomy and controls: flow cytometric measurement of aspirin-induced platelet inhibition.

  Journal of vascular surgery 20070601

• Hyperresponsiveness of platelets in ischemic stroke.

  Thrombosis and haemostasis 20070601

• Simultaneous quantification of seven prostanoids using liquid chromatography/tandem mass spectrometry: the effects of arachidonic acid on prostanoid production in mouse bone marrow-derived mast cells.

  Prostaglandins, leukotrienes, and essential fatty acids 20070601

• Localization of cyclooxygenase-2 in mice testis and assessment of its possible role through suppressing its expression using nimesulide: a preferential cyclooxygenase-2 inhibitor.

  Prostaglandins, leukotrienes, and essential fatty acids 20070601

• [Primary role and extraction of arachidonic acid].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070601

• Heritability of platelet responsiveness to aspirin in activation pathways directly and indirectly related to cyclooxygenase-1.

  Circulation 20070515

• Heritability, platelet function, and aspirin: a link established but cause unknown.

  Circulation 20070515

• Chronic daily administration of ethyl docosahexaenoate protects against gerbil brain ischemic damage through reduction of arachidonic acid liberation and accumulation.

  The Journal of nutritional biochemistry 20070501

• Activation of ERK, JNK, Akt, and G-protein coupled signaling by hybrid angiotensin II AT1/bradykinin B2 receptors expressed in HEK-293 cells.

  Journal of cellular biochemistry 20070501

• Visual acuity and cognitive outcomes at 4 years of age in a double-blind, randomized trial of long-chain polyunsaturated fatty acid-supplemented infant formula.

  Early human development 20070501

• Antinociceptive and antiinflammatory activities of pine (Pinus densiflora) pollen extract.

  Phytotherapy research : PTR 20070501

• Role of Ca2+-independent phospholipase A2gamma in Ca2+-induced mitochondrial permeability transition.

  The Journal of pharmacology and experimental therapeutics 20070501

• The influence of moderate and high dietary long chain polyunsaturated fatty acids (LCPUFA) on baboon neonate tissue fatty acids.

  Pediatric research 20070501

• Antiplatelet activity of geranylgeraniol isolated from Pterodon pubescens fruit oil is mediated by inhibition of cyclooxygenase-1.

  Planta medica 20070501

• n-3 and n-6 polyunsaturated fatty acids induce the expression of COX-2 via PPARgamma activation in human keratinocyte HaCaT cells.

  Biochimica et biophysica acta 20070501

• Effect of omega-3 fatty acid supplementation on the arachidonic acid:eicosapentaenoic acid ratio.

  Pharmacotherapy 20070501

• [Interindividual variability in the laboratory response to the aspirin-clopidogrel combination: are patients with stent occlusion 'resistant' to treatment?].

  Annales pharmaceutiques francaises 20070501

• Variables influencing Multiplate(TM) whole blood impedance platelet aggregometry and turbidimetric platelet aggregation in healthy individuals.

  Platelets 20070501

• PGE synthase inhibitors as an alternative to COX-2 inhibitors.

  Current opinion in investigational drugs (London, England : 2000) 20070501

• Control of cyclic AMP concentration in bovine endometrial stromal cells by arachidonic acid.

  Reproduction (Cambridge, England) 20070501

• Effects of arachidonic acid metabolites on airway sensors.

  Sheng li xue bao : [Acta physiologica Sinica] 20070425

• Arachidonic acid promotes glutamate-induced cell death associated with necrosis by 12- lipoxygenase activation in glioma cells.

  Life sciences 20070424

• Function, activity, and membrane targeting of cytosolic phospholipase A(2)zeta in mouse lung fibroblasts.

  The Journal of biological chemistry 20070420

• Synthesis, isomer characterization, and anti-inflammatory properties of nitroarachidonate.

  Biochemistry 20070417

• Receptor-specific inhibition of GABAB-activated K+ currents by muscarinic and metabotropic glutamate receptors in immature rat hippocampus.

  The Journal of physiology 20070415

• Molecular oxygen dependent steps in fatty acid oxidation by cyclooxygenase-1.

  Biochemistry 20070403

• Fatty acid profiles in hepatic membranes of rats with different levels of circulating estrogen and prolactin.

  Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20070401

• Antiplatelet effect of sanguinarine is correlated to calcium mobilization, thromboxane and cAMP production.

  Atherosclerosis 20070401

• Complementary actions of docosahexaenoic acid and genistein on COX-2, PGE2 and invasiveness in MDA-MB-231 breast cancer cells.

  Carcinogenesis 20070401

• Retinol supplementation in murine Plasmodium berghei malaria: effects on tissue levels, parasitaemia and lipid peroxidation.

  International journal for parasitology 20070401

• P450 CYP2C epoxygenase and CYP4A omega-hydroxylase mediate ciprofibrate-induced PPARalpha-dependent peroxisomal proliferation.

  Journal of lipid research 20070401

• Inhibition of lipopolysaccharide-induced prostaglandin E2 production and inflammation by the Na+/H+ exchanger inhibitors.

  The Journal of pharmacology and experimental therapeutics 20070401

• Peptidoglycan and mannose-based molecular patterns trigger the arachidonic acid cascade in human polymorphonuclear leukocytes.

  Journal of leukocyte biology 20070401

• FTY720 suppresses interleukin-1beta-induced secretory phospholipase A2 expression in renal mesangial cells by a transcriptional mechanism.

  British journal of pharmacology 20070401

• Inhibitory activities and attenuated expressions of 5-LOX with red ginseng in Helicobacter pylori-infected gastric epithelial cells.

  Digestive diseases and sciences 20070401

• Activation of cytosolic phospholipase A2 and 15-lipoxygenase by oxidized low-density lipoproteins in cultured human lung fibroblasts.

  Biochimica et biophysica acta 20070401

• Polyunsaturated fatty acids stimulate phosphatidylcholine synthesis in PC12 cells.

  Biochimica et biophysica acta 20070401

• Mechanism of arachidonic acid action on syntaxin-Munc18.

  EMBO reports 20070401

• Prostaglandin production in human coronary artery endothelial cells is modulated differentially by selective phospholipase A(2) inhibitors.

  Prostaglandins, leukotrienes, and essential fatty acids 20070401

• PLA2 and PI3K/PTEN pathways act in parallel to mediate chemotaxis.

  Developmental cell 20070401

• [The metabolic regulation of cerebral microcirculation].

  Revista de neurologia 20070401

• Polyunsaturated fatty acid supplementation alters proinflammatory gene expression and reduces the incidence of necrotizing enterocolitis in a neonatal rat model.

  Pediatric research 20070401

• Dopamine D2 receptor partial agonists display differential or contrasting characteristics in membrane and cell-based assays of dopamine D2 receptor signaling.

  Progress in neuro-psychopharmacology & biological psychiatry 20070330

• Effect of NC-1900, an active fragment analog of arginine vasopressin, and inhibitors of arachidonic acid metabolism on performance of a passive avoidance task in mice.

  European journal of pharmacology 20070329

• Conformation-sensitive steroid and fatty acid sites in the transmembrane domain of the nicotinic acetylcholine receptor.

  Biochemistry 20070320

• Arachidonic acid potentiates acid-sensing ion channels in rat sensory neurons by a direct action.

  Neuroscience 20070316

• STIM1 regulates Ca2+ entry via arachidonate-regulated Ca2+-selective (ARC) channels without store depletion or translocation to the plasma membrane.

  The Journal of physiology 20070315

• Vanadate-induced activation of cytosolic phospholipase A2alpha in L929 cells: Roles of tyrosine kinase, protein kinase C, and extracellular signal-regulated kinase.

  Biochemical pharmacology 20070315

• Synthesis, pharmacological evaluation and electrochemical studies of novel 6-nitro-3,4-methylenedioxyphenyl-N-acylhydrazone derivatives: Discovery of LASSBio-881, a new ligand of cannabinoid receptors.

  Bioorganic & medicinal chemistry 20070315

• Modulation of the pancreatic islet beta-cell-delayed rectifier potassium channel Kv2.1 by the polyunsaturated fatty acid arachidonate.

  The Journal of biological chemistry 20070309

• Unsaturated fatty acids suppress the expression of the ATP-binding cassette transporter G1 (ABCG1) and ABCA1 genes via an LXR/RXR responsive element.

  Atherosclerosis 20070301

• Cytosolic calcium microdomains by arachidonic acid and nitric oxide in endothelial cells.

  Cell calcium 20070301

• Assessing 12(S)-lipoxygenase inhibitory activity using colorectal cancer cells overexpressing the enzyme.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20070301

• Whey-derived free fatty acids suppress the germination of Candida albicans in vitro.

  FEMS yeast research 20070301

• PLA2 and TRPV4 channels regulate endothelial calcium in cerebral arteries.

  American journal of physiology. Heart and circulatory physiology 20070301

• The macrophage beta-glucan receptor mediates arachidonate release induced by zymosan: essential role for Src family kinases.

  Molecular immunology 20070301

• Long-term docosahexaenoic acid therapy in a congenic murine model of cystic fibrosis.

  American journal of physiology. Gastrointestinal and liver physiology 20070301

• Activation of hEAG1 potassium channels by arachidonic acid.

  Pflugers Archiv : European journal of physiology 20070301

• Modulation of the activity and arachidonic acid selectivity of group X secretory phospholipase A2 by sphingolipids.

  Journal of lipid research 20070301

• Inducible expression of 15-lipoxygenase-2 and 8-lipoxygenase inhibits cell growth via common signaling pathways.

  Journal of lipid research 20070301

• Arachidonic acid potentiates exocytosis and allows neuronal SNARE complex to interact with Munc18a.

  Journal of neurochemistry 20070301

• Docosahexaenoic acid and arachidonic acid are fundamental supplements for the induction of neuronal differentiation.

  Journal of lipid research 20070301

• Three-dimensional quantitative structure-activity relationship analysis of human CYP51 inhibitors.

  Drug metabolism and disposition: the biological fate of chemicals 20070301

• Anti-cyclooxygenase effects of lipid extracts from the New Zealand green-lipped mussel, Perna canaliculus.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20070301

• Abnormalities in the fatty acid composition of the postmortem orbitofrontal cortex of schizophrenic patients: gender differences and partial normalization with antipsychotic medications.

  Schizophrenia research 20070301

• Cytochrome P450-catalyzed pathways in human brain: metabolism meets pharmacology or old drugs with new mechanism of action?

  Pharmacology & therapeutics 20070301

• Exploratory study into the relation between plasma phospholipid fatty acid status and cognitive performance.

  Prostaglandins, leukotrienes, and essential fatty acids 20070301

• Low contribution of n-3 polyunsaturated fatty acids to plasma and erythrocyte membrane lipids in diabetic young adults.

  Prostaglandins, leukotrienes, and essential fatty acids 20070301

• Novel action of n-3 polyunsaturated fatty acids: inhibition of arachidonic acid-induced increase in tumor necrosis factor receptor expression on neutrophils and a role for proteases.

  Arthritis and rheumatism 20070301

• Aspirin resistance: does it exist?

  Seminars in thrombosis and hemostasis 20070301

• Dynamic simulations on the arachidonic acid metabolic network.

  PLoS computational biology 20070301

• Interference by leptin with Helicobacter pylori lipopolysaccharide-induced cytosolic phospholipase A2 activation in gastric mucosal cells.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20070301

• Leukotriene synthesis in response to A23187 is inhibited by methyl- beta-cyclodextrin in RBL-2H3 cells.

  Molecules and cells 20070227

• Dual inhibition of cyclooxygenase and lipoxygenase by human haptoglobin: its polymorphism and relation to hemoglobin binding.

  Biochemical and biophysical research communications 20070223

• Arachidonic and docosahexaenoic acids reduce the growth of A549 human lung-tumor cells increasing lipid peroxidation and PPARs.

  Chemico-biological interactions 20070220

• A liquid chromatography/mass spectrometric method for simultaneous analysis of arachidonic acid and its endogenous eicosanoid metabolites prostaglandins, dihydroxyeicosatrienoic acids, hydroxyeicosatetraenoic acids, and epoxyeicosatrienoic acids in rat brain tissue.

  Journal of pharmaceutical and biomedical analysis 20070219

• Vascular wall-produced prostaglandin E2 exacerbates arterial thrombosis and atherothrombosis through platelet EP3 receptors.

  The Journal of experimental medicine 20070219

• Imaging signal transduction via arachidonic acid in the human brain during visual stimulation, by means of positron emission tomography.

  NeuroImage 20070215

• Thermodynamic and spectroscopic studies on the nickel arachidate-RNA polymerase Langmuir-Blodgett monolayer.

  Langmuir : the ACS journal of surfaces and colloids 20070213

• Baicalein induction of hydroxyl radical formation via 12-lipoxygenase in human platelets: an ESR study.

  Journal of agricultural and food chemistry 20070207

• Bromoenol lactone, an inhibitor of Group V1A calcium-independent phospholipase A2 inhibits antigen-stimulated mast cell exocytosis without blocking Ca2+ influx.

  Cell calcium 20070201

• PKCalpha regulates phosphorylation and enzymatic activity of cPLA2 in vitro and in activated human monocytes.

  Cellular signalling 20070201

• Dietary n-3 PUFA deprivation alters expression of enzymes of the arachidonic and docosahexaenoic acid cascades in rat frontal cortex.

  Molecular psychiatry 20070201

• Adenoviral expression of 15-lipoxygenase-1 in rabbit aortic endothelium: role in arachidonic acid-induced relaxation.

  American journal of physiology. Heart and circulatory physiology 20070201

• Purification by silica gel chromatography using dialysis tubing and characterization of sophorolipids produced from Candida bombicola grown on glucose and arachidonic acid.

  Biotechnology letters 20070201

• Expression of secretory phospholipase A2 in colon tumor cells potentiates tumor growth.

  Molecular carcinogenesis 20070201

• Familial adenomatous polyposis patients have high levels of arachidonic acid and docosahexaenoic acid and low levels of linoleic acid and alpha-linolenic acid in serum phospholipids.

  International journal of cancer 20070201

• The role of membrane lipids in the induction of macrophage apoptosis by microparticles.

  Apoptosis : an international journal on programmed cell death 20070201

• Antioxidant modulation of oxidant-stimulated uptake and release of arachidonic acid in eicosapentaenoic acid-supplemented human lymphoma U937 cells.

  Prostaglandins, leukotrienes, and essential fatty acids 20070201

• Enzymes involved in arachidonic acid release in adrenal and Leydig cells.

  Molecular and cellular endocrinology 20070201

• Docosahexaenoic acid stabilizes soluble amyloid-beta protofibrils and sustains amyloid-beta-induced neurotoxicity in vitro.

  The FEBS journal 20070201

• TRP channels activated by extracellular hypo-osmoticity in epithelia.

  Biochemical Society transactions 20070201

• 5-LOX inhibitor modulates the inflammatory responses provoked by Helicobacter pylori infection.

  Helicobacter 20070201

• Effects of arachidonate metabolism inhibitors on basal and human chorionic gonadotropin-stimulated progesterone secretion by rat corpus luteum cells in vitro.

  Prostaglandins & other lipid mediators 20070201

• Enhancement of acetyl-CoA: 1-O-alkyl-2-lyso-sn-glycero-3-phosphocholine acetyltransferase activity by hydrogen peroxide.

  Biological & pharmaceutical bulletin 20070201

• Identification and functional characterization of polymorphisms in human cyclooxygenase-1 (PTGS1).

  Pharmacogenetics and genomics 20070201

• Essential fatty acid deficiency induces fatty acid desaturase expression in rat epididymis, but not in testis.

  Reproduction (Cambridge, England) 20070201

• Effects of dietary arachidonic acid supplementation on age-related changes in endothelium-dependent vascular responses.

  Journal of nutritional science and vitaminology 20070201

• Haloperidol targets brain arachidonic acid signaling.

  Progress in neuro-psychopharmacology & biological psychiatry 20070130

• Chemical determinants involved in anandamide-induced inhibition of T-type calcium channels.

  The Journal of biological chemistry 20070126

• Letter by Kronish et al regarding article, 'Residual arachidonic acid-induced platelet activation via an adenosine diphosphate-dependent but cyclooxygenase-1- and cyclooxygenase-2-independent pathway: a 700-patient study of aspirin resistance'.

  Circulation 20070123

• RETRACTED: Chronic administration of carbamazepine down-regulates AP-2 DNA-binding activity and AP-2alpha protein expression in rat frontal cortex.

  Biological psychiatry 20070115

• TRPV1 is a novel target for omega-3 polyunsaturated fatty acids.

  The Journal of physiology 20070115

• Role of intracellular calcium and phospholipase A2 in arachidonic acid-induced toxicity in liver cells overexpressing CYP2E1.

  Archives of biochemistry and biophysics 20070115

• Formation of methionine sulfoxide during glycoxidation and lipoxidation of ribonuclease A.

  Archives of biochemistry and biophysics 20070115

• Arachidonic acid metabolism as a potential mediator of cardiac fibrosis associated with inflammation.

  Journal of immunology (Baltimore, Md. : 1950) 20070115

• Interaction between the SH3 domains and C-terminal proline-rich region in NADPH oxidase organizer 1 (Noxo1).

  Biochemical and biophysical research communications 20070112

• [Relations of platelet phospholipid fatty acids to thrombotic risk factors in middle-aged and geriatric patients with hyperlipidemia].

  Zhonghua yi xue za zhi 20070109

• Albumin-bound lipids induce free cytoplasmic calcium oscillations in human osteoblast-like cells.

  Cell biochemistry and function 20070101

• Aripiprazole has functionally selective actions at dopamine D2 receptor-mediated signaling pathways.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20070101

• Effects of arachidonic acid, docosahexaenoic acid, prostaglandin E(2) and parathyroid hormone on osteoprotegerin and RANKL secretion by MC3T3-E1 osteoblast-like cells.

  The Journal of nutritional biochemistry 20070101

• Interaction between store-operated and arachidonate-activated calcium entry.

  Cell calcium 20070101

• Altered membrane free unsaturated fatty acid composition in human colorectal cancer tissue.

  Molecular and cellular biochemistry 20070101

• Lysophosphatidylcholine induces inflammatory activation of human coronary artery smooth muscle cells.

  Molecular and cellular biochemistry 20070101

• Calcium-independent phospholipase A2-catalyzed plasmalogen hydrolysis in hypoxic human coronary artery endothelial cells.

  American journal of physiology. Cell physiology 20070101

• Di-(2-ethylhexyl)-phthalate affects lipid profiling in fetal rat brain upon maternal exposure.

  Archives of toxicology 20070101

• Uric acid inhibits renal proximal tubule cell proliferation via at least two signaling pathways involving PKC, MAPK, cPLA2, and NF-kappaB.

  American journal of physiology. Renal physiology 20070101

• ERK1/2 regulates two sequential steps promoting monocyte survival to peroxynitrite.

  Journal of cellular physiology 20070101

• Clozapine specifically alters the arachidonic acid pathway in mice lacking apolipoprotein D.

  Schizophrenia research 20070101

• Beta-subunit-dependent modulation of hSlo BK current by arachidonic acid.

  Journal of neurophysiology 20070101

• Phospholipase A2-catalyzed hydrolysis of plasmalogen phospholipids in thrombin-stimulated human platelets.

  Thrombosis research 20070101

• Maternal dietary n-3 fatty acids alter immune cell fatty acid composition and leukotriene production in growing chicks.

  Prostaglandins, leukotrienes, and essential fatty acids 20070101

• Chronic fluoxetine increases cytosolic phospholipase A(2) activity and arachidonic acid turnover in brain phospholipids of the unanesthetized rat.

  Psychopharmacology 20070101

• Cryptococcal lipid metabolism: phospholipase B1 is implicated in transcellular metabolism of macrophage-derived lipids.

  Eukaryotic cell 20070101

• Effects of arachidonic acid, docosahexaenoic acid and prostaglandin E(2) on cell proliferation and morphology of MG-63 and MC3T3-E1 osteoblast-like cells.

  Prostaglandins, leukotrienes, and essential fatty acids 20070101

• Induction of apoptosis in an estrogen-responsive mouse Leydig tumor cell by leukotriene.

  Oncology reports 20070101

• Beyond vasodilatation: non-vasomotor roles of epoxyeicosatrienoic acids in the cardiovascular system.

  Trends in pharmacological sciences 20070101

• Aspirin-sensitive rhinosinusitis and asthma.

  Clinical allergy and immunology 20070101

• Erythrocyte-derived epoxyeicosatrienoic acids.

  Prostaglandins & other lipid mediators 20070101

• Emerging mechanisms for growth and protection of the vasculature by cytochrome P450-derived products of arachidonic acid and other eicosanoids.

  Prostaglandins & other lipid mediators 20070101

• Soluble epoxide hydrolase inhibition reveals novel biological functions of epoxyeicosatrienoic acids (EETs).

  Prostaglandins & other lipid mediators 20070101

• Why isn't the causal relationship between linoleic acid and mortalities from coronary heart disease and stroke revealed by clinical studies?

  World review of nutrition and dietetics 20070101

• B cell lymphoma 10 is essential for FcepsilonR-mediated degranulation and IL-6 production in mast cells.

  Journal of immunology (Baltimore, Md. : 1950) 20070101

• Protease activation of calcium-independent phospholipase A2 leads to neutrophil recruitment to coronary artery endothelial cells.

  Thrombosis research 20070101

• Effect of azoxymethane and curcumin on transcriptional levels of cyclooxygenase-1 and -2 during initiation of colon carcinogenesis.

  Scandinavian journal of gastroenterology 20070101

• Purified eicosapentaenoic acid reduces small dense LDL, remnant lipoprotein particles, and C-reactive protein in metabolic syndrome.

  Diabetes care 20070101

• The role of arachidonic acid and its metabolites in insulin secretion from human islets of langerhans.

  Diabetes 20070101

• Gliotoxin from Aspergillus fumigatus affects phagocytosis and the organization of the actin cytoskeleton by distinct signalling pathways in human neutrophils.

  Microbes and infection 20070101

• Altered omega-3 polyunsaturated fatty acid status in depressed post-myocardial infarction patients.

  Acta psychiatrica Scandinavica 20070101

• Arachidonic acid content in adipose tissue is associated with insulin resistance in healthy children.

  Journal of pediatric gastroenterology and nutrition 20070101

• Elongation of polyunsaturated fatty acids in trypanosomatids.

  The FEBS journal 20070101

• Effect of oversulfated dermatan sulfate derivatives on platelet aggregation.

  Thrombosis research 20070101

• In-vitro and in-vivo anti-inflammatory action of the ethanol extract of Trachelospermi caulis.

  The Journal of pharmacy and pharmacology 20070101

• Comparison of a rapid platelet function assay--Verify Now Aspirin--with whole blood impedance aggregometry for the detection of aspirin resistance.

  Thrombosis research 20070101

• Normalization of platelet reactivity in clopidogrel-treated subjects.

  Journal of thrombosis and haemostasis : JTH 20070101

• Arachidonic acid inhibits osteoblast differentiation through cytosolic phospholipase A2-dependent pathway.

  Oral diseases 20070101

• Regulation of endothelial cell migration by amphiphiles - are changes in cell membrane physical properties involved?

  Angiogenesis 20070101

• Design of original bioactive formulations based on sugar-surfactant/non-steroidal anti-inflammatory catanionic self-assemblies: a new way of dermal drug delivery.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20070101

• Licofelone--a novel analgesic and anti-inflammatory agent.

  Current topics in medicinal chemistry 20070101

• New approaches to the modulation of the cyclooxygenase-2 and 5-lipoxygenase pathways.

  Current topics in medicinal chemistry 20070101

• Effect of acetylsalicylic acid on aggregation of human platelets by Porphyromonas gingivalis.

  General dentistry 20070101

• Effects of unsaturated free fatty acids on adhesion and on gene expression of extracellular matrix macromolecules in human osteoblast-like cell cultures.

  Connective tissue research 20070101

• Regulation of the NADPH oxidase activity and anti-microbial function of neutrophils by arachidonic acid.

  Archivum immunologiae et therapiae experimentalis 20070101

• N-(p-amylcinnamoyl)anthranilic acid (ACA): a phospholipase A(2) inhibitor and TRP channel blocker.

  Cardiovascular drug reviews 20070101

• Separation and preparative purification of arachidonic acid from microbial lipids by urea inclusion reaction and HPLC.

  Preparative biochemistry & biotechnology 20070101

• PLA2 mediated arachidonate free radicals: PLA2 inhibition and neutralization of free radicals by anti-oxidants--a new role as anti-inflammatory molecule.

  Current topics in medicinal chemistry 20070101

• Chemistry and structural evaluation of different phospholipase A2 inhibitors in arachidonic acid pathway mediated inflammation and snake venom toxicity.

  Current topics in medicinal chemistry 20070101

• Cellular and molecular mechanisms regulating vascular tone. Part 2: regulatory mechanisms modulating Ca2+ mobilization and/or myofilament Ca2+ sensitivity in vascular smooth muscle cells.

  Journal of anesthesia 20070101

• Assessing aspirin-induced attenuation of platelet reactivity by flow cytometry.

  Thrombosis research 20070101

• The role of cyclooxygenase in the feline pulmonary vascular bed.

  American journal of therapeutics 20070101

• Variable platelet response to aspirin in patients with ischemic stroke.

  Cerebrovascular diseases (Basel, Switzerland) 20070101

• Reproducibility of platelet function testing.

  Laboratory hematology : official publication of the International Society for Laboratory Hematology 20070101

• Arachidonic acid can significantly prevent early insulin resistance induced by a high-fat diet.

  Annals of nutrition & metabolism 20070101

• Acetaminophen, phenacetin and dipyrone do not modulate pressor responses to arachidonic Acid or to pressor agents.

  Pharmacology 20070101

• Control of the growth of human breast cancer cells in culture by manipulation of arachidonate metabolism.

  BMC cancer 20070101

• Platelet aggregation and physiological anticoagulants in sickle-cell disease.

  Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit 20070101

• Cross-talk between NO and arachidonic acid in inflammation.

  Current medicinal chemistry 20070101

• Antileukotriene drugs: clinical application, effectiveness and safety.

  Current medicinal chemistry 20070101

• Roles of long-chain polyunsaturated fatty acids in the term infant: developmental benefits.

  Neonatal network : NN 20070101

• Amyloid beta enhances cytosolic phospholipase A2 level and arachidonic acid release via nitric oxide in APP-transfected PC12 cells.

  Acta biochimica Polonica 20070101

• Anti-apoptotic effects of arachidonic acid and prostaglandin E2 in pancreatic beta-cells.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20070101

• Endogenous receptor agonists: resolving inflammation.

  TheScientificWorldJournal 20070101

• The presence of arachidonic acid-activated K+ channel, TREK-1, in human periodontal ligament fibroblasts.

  Drug metabolism reviews 20070101

• Sensitivity of fetus and pups to excess levels of maternal intakes of alpha linolenic acid at marginal protein levels in Wistar rats.

  Reproductive toxicology (Elmsford, N.Y.) 20070101

• Role of cytochrome P450 metabolites of arachidonic acid in regulation of corporal smooth muscle tone in diabetic and older rats.

  Vascular pharmacology 20070101

• Modulation of hypericin photodynamic therapy by pretreatment with 12 various inhibitors of arachidonic acid metabolism in colon adenocarcinoma HT-29 cells.

  Photochemistry and photobiology 20070101

• Examining the collision-induced decomposition spectra of ammoniated triglycerides. III. The linoleate and arachidonate series.

  Rapid communications in mass spectrometry : RCM 20070101

• [Mechanisms of the protease-induced aggregation of human platelets].

  Biofizika 20070101

• Supplementation of arachidonic acid plus docosahexaenoic acid in cirrhotic patients awaiting liver transplantation: a preliminary study.

  JPEN. Journal of parenteral and enteral nutrition 20070101

• Hydrogen peroxide increases [3H]-2-deoxyglucose uptake via MAPKs, cPLA2, and NF-kappaB signaling pathways in mouse embryonic stem cells.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20070101

• Effects of inhibitors of the arachidonic acid cascade on primary muscle culture from a Duchenne muscular dystrophy patient.

  Prostaglandins, leukotrienes, and essential fatty acids 20070101

• The influence of dietary docosahexaenoic acid and arachidonic acid on central nervous system polyunsaturated fatty acid composition.

  Prostaglandins, leukotrienes, and essential fatty acids 20070101

• Plasma arachidonic acid influences insulin-stimulated glucose uptake in healthy adult women.

  Annals of nutrition & metabolism 20070101

• Lipid analysis of normal dermis and hypertrophic scars.

  Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 20070101

• Fatty acid alterations and n-3 fatty acid supplementation in cystic fibrosis.

  Prostaglandins, leukotrienes, and essential fatty acids 20070101

• Role of RXR in neurite outgrowth induced by docosahexaenoic acid.

  Prostaglandins, leukotrienes, and essential fatty acids 20070101

• Antimanic therapies target brain arachidonic acid signaling: lessons learned about the regulation of brain fatty acid metabolism.

  Prostaglandins, leukotrienes, and essential fatty acids 20070101

• Phospholipase A2 activation regulates cytotoxicity of methylmercury in vascular endothelial cells.

  International journal of toxicology 20070101

• [New aspects of biosynthesis and metabolism of N-acyldopamines in rat tissues].

  Bioorganicheskaia khimiia 20070101

• Alpha-synuclein decreases arachidonic acid incorporation into rat striatal synaptoneurosomes.

  Folia neuropathologica 20070101

• Effects of ebselen on glutathione level in neurons exposed to arachidonic acid and 4-hydroxynonenal during simulated ischemia in vitro.

  Pharmacological reports : PR 20070101

• The phospholipidosis-lnducing potential of the chemopotentiating drug, N,N-Diethyl-2-[4-(phenylmethyl)phenoxy]ethanamine (DPPE, tesmilifene) correlates with its stimulation of phosphatidylserine synthesis and exposure on the plasma membrane in MCF-7 breast cancer cells.

  Proceedings of the Western Pharmacology Society 20070101

• The oestrogen receptor beta contributes to sex related differences in endothelial function of murine small arteries via EDHF.

  The Journal of physiology 20061215

• Apoptotic cells, through transforming growth factor-beta, coordinately induce anti-inflammatory and suppress pro-inflammatory eicosanoid and NO synthesis in murine macrophages.

  The Journal of biological chemistry 20061215

• Cyclooxygenase regulates cell surface expression of CXCR3/1-storing granules in human CD4+ T cells.

  Journal of immunology (Baltimore, Md. : 1950) 20061215

• AKAP150, a switch to convert mechano-, pH- and arachidonic acid-sensitive TREK K(+) channels into open leak channels.

  The EMBO journal 20061213

• Lipid profiling reveals arachidonate deficiency in RAW264.7 cells: Structural and functional implications.

  Biochemistry 20061212

• Glycosylation regulates turnover of cyclooxygenase-2.

  FEBS letters 20061211

• Polymer-surfactant layered heterostructures by electropolymerization of phenosafranine in Langmuir-Blodgett films.

  The journal of physical chemistry. B 20061207

• Evaluation of the role of the arachidonic acid cascade in anandamide's in vivo effects in mice.

  Life sciences 20061203

• Chronic fluoxetine upregulates arachidonic acid incorporation into the brain of unanesthetized rats.

  European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20061201

• Signal pathways involved in the regulation of prostaglandin E synthase-1 in human gingival fibroblasts.

  Cellular signalling 20061201

• Galpha13 mediates activation of the cytosolic phospholipase A2alpha through fine regulation of ERK phosphorylation.

  Cellular signalling 20061201

• Low Na intake suppresses expression of CYP2C23 and arachidonic acid-induced inhibition of ENaC.

  American journal of physiology. Renal physiology 20061201

• Roles of phospholipase A2 isoforms in swelling- and melittin-induced arachidonic acid release and taurine efflux in NIH3T3 fibroblasts.

  American journal of physiology. Cell physiology 20061201

• Restricted diet modifies carbohydrate metabolism in immature rats.

  Prostaglandins, leukotrienes, and essential fatty acids 20061201

• Venlafaxine-induced ecchymoses and impaired platelet aggregation.

  European journal of haematology 20061201

• Hydroxyeicosatetraenoic acids released through the cytochrome P-450 pathway regulate 3T6 fibroblast growth.

  Journal of lipid research 20061201

• Peracetylation as a means of enhancing in vitro bioactivity and bioavailability of epigallocatechin-3-gallate.

  Drug metabolism and disposition: the biological fate of chemicals 20061201

• MAPK-activated protein kinase-2 (MK2)-mediated formation and phosphorylation-regulated dissociation of the signal complex consisting of p38, MK2, Akt, and Hsp27.

  The Journal of biological chemistry 20061201

• CYP2E1 induced by ethanol causes oxidative stress, proteasome inhibition and cytokeratin aggresome (Mallory body-like) formation.

  Experimental and molecular pathology 20061201

• Involvement of cyclooxygenase-2--prostaglandin E2 pathway in interleukin-8 production in gastric cancer cells.

  Digestive diseases and sciences 20061201

• Regulation of exocytosis in chromaffin cells by trans-insertion of lysophosphatidylcholine and arachidonic acid into the outer leaflet of the cell membrane.

  Chembiochem : a European journal of chemical biology 20061201

• Leptin modulates the detrimental effect of Porphyromonas gingivalis lipopolysaccharide-induced cytosolic phospholipase A2 activation on salivary mucin synthesis via ERK-signal transduction.

  Inflammopharmacology 20061201

• Activation and impairment of platelet function in vitro by fatty acid ethyl ester, a nonoxidative ethanol metabolite: effect of fatty acid ethyl esters on human platelets.

  Alcoholism, clinical and experimental research 20061201

• Effects on primary haemostasis of an anti-inflammatory agent with 5-lipoxygenase and cyclooxygenase inhibitory activity.

  Journal of cardiovascular medicine (Hagerstown, Md.) 20061201

• Metabolic basis for the essential nature of fatty acids and the unique dietary fatty acid requirements of cats.

  Journal of the American Veterinary Medical Association 20061201

• Systemic elevations of free radical oxidation products of arachidonic acid are associated with angiographic evidence of coronary artery disease.

  Free radical biology & medicine 20061201

• Docosahexaenoic acid (22:6n-3) enrichment of membrane phospholipids increases gap junction coupling capacity in cultured astrocytes.

  The European journal of neuroscience 20061201

• Aureispira marina gen. nov., sp. nov., a gliding, arachidonic acid-containing bacterium isolated from the southern coastline of Thailand.

  International journal of systematic and evolutionary microbiology 20061201

• Modulation of neuronal T-type calcium channels.

  CNS & neurological disorders drug targets 20061201

• New insights into the regulation of liver inflammation and oxidative stress.

  Mini reviews in medicinal chemistry 20061201

• Eicosanoids, aspirin-intolerance and the upper airways--current standards and recent improvements of the desensitization therapy.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20061201

• Functional analysis of eicosanoids from white blood cells in sepsis and SIRS.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20061201

• Testing and typing of eicosanoid-patterns.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20061201

• Effect of lipids extracted from a salted herring roe food product on maze-behavior in mice.

  Journal of nutritional science and vitaminology 20061201

• Engineering of a protein with cyclooxygenase and prostacyclin synthase activities that converts arachidonic acid to prostacyclin.

  Biochemistry 20061128

• The inhibitory effect of polyunsaturated fatty acids on human CYP enzymes.

  Life sciences 20061125

• Group VIA calcium-independent phospholipase A2 mediates endothelial cell S phase progression.

  The Journal of biological chemistry 20061124

• In vivo and in vitro lipid peroxidation of arachidonate esters: the effect of fish oil omega-3 lipids on product distribution.

  Journal of the American Chemical Society 20061122

• What are cyclooxygenases and lipoxygenases doing in the driver's seat of carcinogenesis?

  International journal of cancer 20061115

• [Resolvins: new derivates of fatty acids, polyunsaturated (omega-3) with therapeutic potential in inflammatory intestinal diseases].

  Revue medicale suisse 20061115

• Prostacyclin therapy increases right ventricular capillarisation in a model for flow-associated pulmonary hypertension.

  European journal of pharmacology 20061107

• Neuroprotective effects of arachidonic acid against oxidative stress on rat hippocampal slices.

  Chemico-biological interactions 20061107

• Cryptotanshinone inhibits cyclooxygenase-2 enzyme activity but not its expression.

  European journal of pharmacology 20061107

• Inhibitory effects of Tabebuia impetiginosa inner bark extract on platelet aggregation and vascular smooth muscle cell proliferation through suppressions of arachidonic acid liberation and ERK1/2 MAPK activation.

  Journal of ethnopharmacology 20061103

• D-Amphetamine stimulates D2 dopamine receptor-mediated brain signaling involving arachidonic acid in unanesthetized rats.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20061101

• Thromboxane mediates neutrophil superoxide production in pregnancy.

  American journal of obstetrics and gynecology 20061101

• PCB 50 stimulates release of arachidonic acid and prostaglandins from late gestation rat amnion fibroblast cells.

  Reproductive toxicology (Elmsford, N.Y.) 20061101

• Contributions of cyclooxygenase-2 to neuroplasticity and neuropathology of the central nervous system.

  Pharmacology & therapeutics 20061101

• Cytochrome P450 enzymes: central players in cardiovascular health and disease.

  Pharmacology & therapeutics 20061101

• Induction of apoptosis in estrogen receptor-negative breast cancer cells by natural and synthetic cyclopentenones: role of the IkappaB kinase/nuclear factor-kappaB pathway.

  Molecular pharmacology 20061101

• Group V sPLA2: classical and novel functions.

  Biochimica et biophysica acta 20061101

• Prostaglandin E2 release in gastric antral mucosa of guinea-pigs: basal PGE2 release by cyclo-oxygenase 2 and ACh-stimulated PGE2 release by cyclo-oxygenase 1.

  Experimental physiology 20061101

• Calcium-independent phospholipase A2 and apoptosis.

  Biochimica et biophysica acta 20061101

• Phospholipase A2-modified low-density lipoprotein activates the phosphatidylinositol 3-kinase-Akt pathway and increases cell survival in monocytic cells.

  Arteriosclerosis, thrombosis, and vascular biology 20061101

• Control of phospholipase A2 activities for the treatment of inflammatory conditions.

  Biochimica et biophysica acta 20061101

• Molecular and functional changes of pulmonary surfactant in response to hyperoxia.

  Pediatric pulmonology 20061101

• Time course changes of scratching counts, dermatitis symptoms, and levels of cutaneous prostaglandins in NC/Nga mice.

  Experimental dermatology 20061101

• Infants fed docosahexaenoic acid- and arachidonic acid-supplemented formula have decreased incidence of bronchiolitis/bronchitis the first year of life.

  Clinical pediatrics 20061101

• Roles of cPLA2alpha and arachidonic acid in cancer.

  Biochimica et biophysica acta 20061101

• Evidence against calcium as a mediator of mitochondrial dysfunction during apoptosis induced by arachidonic acid and other free fatty acids.

  Journal of immunology (Baltimore, Md. : 1950) 20061101

• Neurotoxicity of lidocaine involves specific activation of the p38 mitogen-activated protein kinase, but not extracellular signal-regulated or c-jun N-terminal kinases, and is mediated by arachidonic acid metabolites.

  Anesthesiology 20061101

• cAMP increases mitochondrial cholesterol transport through the induction of arachidonic acid release inside this organelle in Leydig cells.

  The FEBS journal 20061101

• Conjugated linoleic acid, unlike other unsaturated fatty acids, strongly induces glutathione synthesis without any lipoperoxidation.

  The British journal of nutrition 20061101

• Five-lipoxygenase pathway of arachidonic acid metabolism in carcino-genesis and cancer chemoprevention.

  Current cancer drug targets 20061101

• Cytochrome P-450 monooxygenases in control of renal haemodynamics and arterial pressure in anaesthetized rats.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20061101

• Regulation of cell proliferation and apoptosis by bioactive lipid mediators.

  Recent patents on anti-cancer drug discovery 20061101

• N-terminal fragments of tau inhibit full-length tau polymerization in vitro.

  Biochemistry 20061024

• Oxidative stability of algal oils as affected by their minor components.

  Journal of agricultural and food chemistry 20061018

• Nitric oxide donors prevent while the nitric oxide synthase inhibitor L-NAME increases arachidonic acid plus CYP2E1-dependent toxicity.

  Toxicology and applied pharmacology 20061015

• n-6 and n-3 polyunsaturated fatty acids down-regulate cytochrome P-450 2B1 gene expression induced by phenobarbital in primary rat hepatocytes.

  The Journal of nutritional biochemistry 20061001

• Attenuation of mycotoxin-induced IgA nephropathy by eicosapentaenoic acid in the mouse: dose response and relation to IL-6 expression.

  The Journal of nutritional biochemistry 20061001

• Fatty acid-induced toxicity and neutral lipid accumulation in insulin-producing RINm5F cells.

  Toxicology in vitro : an international journal published in association with BIBRA 20061001

• Arachidonic acid-induced gene expression in colon cancer cells.

  Carcinogenesis 20061001

• Differential effects of 5-methyl-1-[[2-[(2-methyl-3-pyridyl)oxyl]-5-pyridyl]carbamoyl]-6-trifluoromethylindone (SB 243213) on 5-hydroxytryptamine(2C) receptor-mediated responses.

  The Journal of pharmacology and experimental therapeutics 20061001

• Involvement of multitargets in paeoniflorin-induced preconditioning.

  The Journal of pharmacology and experimental therapeutics 20061001

• Inhibition of protein kinase Cbeta protects against diabetes-induced impairment in arachidonic acid dilation of small coronary arteries.

  The Journal of pharmacology and experimental therapeutics 20061001

• Reduction of cardiovascular risk factors with longterm fish oil treatment in early rheumatoid arthritis.

  The Journal of rheumatology 20061001

• 5-Hydroxyeicosatetraenoic acid is a key intermediate of the arachidonate-dependent protective signaling in monocytes/macrophages exposed to peroxynitrite.

  Journal of leukocyte biology 20061001

• Cis-unsaturated fatty acids stimulate reactive oxygen species generation and lipid peroxidation in human spermatozoa.

  The Journal of clinical endocrinology and metabolism 20061001

• Dietary supplementation of arachidonic and docosahexaenoic acids improves cognitive dysfunction.

  Neuroscience research 20061001

• Dietary arachidonic acid and docosahexaenoic acid elevate femur calcium and reduce zinc content in piglets.

  Pediatric research 20061001

• Decreased polyunsaturated and increased saturated fatty acid concentration in spermatozoa from asthenozoospermic males as compared with normozoospermic males.

  Andrologia 20061001

• Risk of colorectal cancer is linked to erythrocyte compositions of fatty acids as biomarkers for dietary intakes of fish, fat, and fatty acids.

  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20061001

• [Blood-tumor barrier in malignant brain tumor].

  No shinkei geka. Neurological surgery 20061001

• Anti-inflammatory action of phenolic compounds from Gastrodia elata root.

  Archives of pharmacal research 20061001

• Effects of methyl gallate on arachidonic acid metabolizing enzymes: Cyclooxygenase-2 and 5-lipoxygenase in mouse bone marrow-derived mast cells.

  Archives of pharmacal research 20061001

• Antiplatelet and antithrombotic activities of Korean Red Ginseng.

  Archives of pharmacal research 20061001

• [Fish, n-3 polyunsaturated fatty acid and colorectal cancer prevention: a review of experimental and epidemiological studies].

  [Nihon koshu eisei zasshi] Japanese journal of public health 20061001

• Altered arachidonic acid-mediated responses in the perfused kidney of the streptozotocin-induced diabetic rat.

  Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20061001

• Evidence that 20-HETE contributes to the development of acute and delayed cerebral vasospasm.

  Neurological research 20061001

• [Leukotrienes: potential therapeutic targets in cardiovascular diseases].

  Bulletin de l'Academie nationale de medecine 20061001

• Differential production of leukotriene B4 or prostaglandin E2 by WKYMVm or serum amyloid A via formyl peptide receptor-like 1.

  Biochemical pharmacology 20060928

• Hydrogen peroxide-induced arachidonic acid release in L929 cells; roles of Src, protein kinase C and cytosolic phospholipase A2alpha.

  European journal of pharmacology 20060928

• 1-Aminomethylbenzocycloalkanes: conformationally restricted hallucinogenic phenethylamine analogues as functionally selective 5-HT2A receptor agonists.

  Journal of medicinal chemistry 20060921

• Relation between atherosclerosis risk factors and aspirin resistance in a primary prevention population.

  The American journal of cardiology 20060915

• Effect of aspirin dose, preparation, and withdrawal on platelet response in normal volunteers.

  The American journal of cardiology 20060915

• Activation of phospholipase Cepsilon by free fatty acids and cross talk with phospholipase D and phospholipase A2.

  Biochemistry 20060912

• Up-regulation of cytosolic phospholipase A2alpha expression by N,N-diethyldithiocarbamate in PC12 cells; involvement of reactive oxygen species and nitric oxide.

  Toxicology and applied pharmacology 20060901

• Cyclooxygenases, lipoxygenases, and epoxygenases in CNS: their role and involvement in neurological disorders.

  Brain research reviews 20060901

• Inflammation effects on the electrical properties of atrial tissue and inducibility of postoperative atrial fibrillation.

  The Journal of surgical research 20060901

• Boswellic acids stimulate arachidonic acid release and 12-lipoxygenase activity in human platelets independent of Ca2+ and differentially interact with platelet-type 12-lipoxygenase.

  Molecular pharmacology 20060901

• Cardiac and vascular KATP channels in rats are activated by endogenous epoxyeicosatrienoic acids through different mechanisms.

  The Journal of physiology 20060901

• Oxygenation of omega-3 fatty acids by human cytochrome P450 4F3B: effect on 20-hydroxyeicosatetraenoic acid production.

  Prostaglandins, leukotrienes, and essential fatty acids 20060901

• Group IVA phospholipase A2-mediated production of fibronectin by oxidized LDL in mesangial cells.

  Kidney international 20060901

• Effects of sphingosine-1-phosphate and ceramide-1-phosphate on rat intestinal smooth muscle cells: implications for postoperative ileus.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060901

• Antiplatelet activity of carnosol is mediated by the inhibition of TXA2 receptor and cytosolic calcium mobilization.

  Vascular pharmacology 20060901

• Brain elongation of linoleic acid is a negligible source of the arachidonate in brain phospholipids of adult rats.

  Biochimica et biophysica acta 20060901

• Arachidonic acid can function as a signaling modulator by activating the TRPM5 cation channel in taste receptor cells.

  Biochimica et biophysica acta 20060901

• Uterine transcriptomes of bacteria-induced and ovariectomy-induced preterm labor in mice are characterized by differential expression of arachidonate metabolism genes.

  American journal of obstetrics and gynecology 20060901

• Celecoxib, ibuprofen, and the antiplatelet effect of aspirin in patients with osteoarthritis and ischemic heart disease.

  Clinical pharmacology and therapeutics 20060901

• Eicosanoid transcellular biosynthesis: from cell-cell interactions to in vivo tissue responses.

  Pharmacological reviews 20060901

• Inhibition of arachidonic acid release by cytosolic phospholipase A2 is involved in the antiapoptotic effect of FK506 and cyclosporin a on astrocytes exposed to simulated ischemia in vitro.

  Journal of pharmacological sciences 20060901

• The involvement of epoxygenase metabolites of arachidonic acid in cAMP-stimulated steroidogenesis and steroidogenic acute regulatory protein gene expression.

  The Journal of endocrinology 20060901

• Mechanisms of cancer prevention by green and black tea polyphenols.

  Anti-cancer agents in medicinal chemistry 20060901

• [Study on arachidonic acid metabolism and collagen production in keloids].

  [Hokkaido igaku zasshi] The Hokkaido journal of medical science 20060901

• [The blood platelets in parasitic diseases].

  Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20060901

• Is body size a biomarker for optimizing dosing of omega-3 polyunsaturated fatty acids in the treatment of patients with IgA nephropathy?

  Clinical journal of the American Society of Nephrology : CJASN 20060901

• Topical anti-inflammatory activity of 2alpha-hydroxy pentacyclic triterpene acids from the leaves of Ugni molinae.

  Bioorganic & medicinal chemistry 20060815

• Nimesulide-induced antipyresis in rats involves both cyclooxygenase-dependent and independent mechanisms.

  European journal of pharmacology 20060814

• Distinct mono- and dinucleotide-specific P2Y receptors in A549 lung epithelial cells: different control of arachidonic acid release and nitric oxide synthase expression.

  European journal of pharmacology 20060814

• [Fatty acid composition of human milk in mothers of preterm and full-term infants in the first three weeks of lactation].

  Orvosi hetilap 20060806

• Identification and functional characterization of the moss Physcomitrella patens delta5-desaturase gene involved in arachidonic and eicosapentaenoic acid biosynthesis.

  The Journal of biological chemistry 20060804

• Cytosolic prostaglandin E2 synthase (cPGES) expression is decreased in discrete cortical regions in psychiatric disease.

  Brain research 20060804

• Antiplatelet property of Curcuma longa L. rhizome-derived ar-turmerone.

  Bioresource technology 20060801

• Chronic lithium chloride administration attenuates brain NMDA receptor-initiated signaling via arachidonic acid in unanesthetized rats.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20060801

• Epoxyeicosatrienoic acids in cardioprotection: ischemic versus reperfusion injury.

  American journal of physiology. Heart and circulatory physiology 20060801

• Staphylococcal enterotoxin B initiates protein kinase C translocation and eicosanoid metabolism while inhibiting thrombin-induced aggregation in human platelets.

  Molecular and cellular biochemistry 20060801

• Evidence for two-pore domain potassium channels in rat cerebral arteries.

  American journal of physiology. Heart and circulatory physiology 20060801

• Having a heart attack? Avoid the 'HETE'!

  American journal of physiology. Heart and circulatory physiology 20060801

• Mediator mechanisms involved in TRPV1 and P2X receptor-mediated, ROS-evoked bradypneic reflex in anesthetized rats.

  Journal of applied physiology (Bethesda, Md. : 1985) 20060801

• Effect of arachidonic and eicosapentaenoic acid metabolism on RAW 264.7 macrophage proliferation.

  Journal of cellular physiology 20060801

• Influence on platelet aggregation of i.v. parecoxib and acetaminophen in healthy volunteers.

  British journal of anaesthesia 20060801

• Induction of CYP1A and cyp2-mediated arachidonic acid epoxygenation and suppression of 20-hydroxyeicosatetraenoic acid by imidazole derivatives including the aromatase inhibitor vorozole.

  Drug metabolism and disposition: the biological fate of chemicals 20060801

• Biphasic regulation of extracellular signal-regulated kinases by scalaradial, a secretory phospholipase A(2) inhibitor.

  Cancer biology & therapy 20060801

• Arachidonic acid influences intracellular calcium handling in human osteoblasts.

  Prostaglandins, leukotrienes, and essential fatty acids 20060801

• Male cardiovascular mortality and dietary markers in 25 population samples of 16 countries.

  Journal of hypertension 20060801

• 15-Hydroperoxyeicosapentaenoic acid, but not eicosapentaenoic acid, shifts arachidonic acid away from cyclooxygenase pathway into acyl-CoA synthetase pathway in rabbit kidney medulla microsomes.

  Prostaglandins, leukotrienes, and essential fatty acids 20060801

• Heterogeneity in the suppression of platelet cyclooxygenase-1 activity by aspirin in coronary heart disease.

  Clinical pharmacology and therapeutics 20060801

• Effects of physical conditioning on lipids and arachidonic acid metabolites in untrained boys: a longitudinal study.

  Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 20060801

• Thr-encoding allele homozygosity at codon 54 of FABP 2 gene may be associated with impaired delta 6 desatruase activity and reduced plasma arachidonic acid in obese children.

  Journal of atherosclerosis and thrombosis 20060801

• Arachidonic acid enhances intracellular [Ca2+]i increase and mitochondrial depolarization induced by glutamate in cerebellar granule cells.

  Biochemistry. Biokhimiia 20060801

• Porphyromonas gingivalis lipopolysaccharide-induced cytosolic phospholipase A2 activation interferes with salivary mucin synthesis via platelet activating factor generation.

  Inflammopharmacology 20060801

• The positive feedback role of arachidonic acid in the platelet-derived growth factor-induced signaling in lens epithelial cells.

  Molecular vision 20060726

• Stimulation of arachidonic acid release by vasopressin in A7r5 vascular smooth muscle cells mediated by Ca2+-stimulated phospholipase A2.

  FEBS letters 20060724

• Polymorphisms in the genes involved in the arachidonic acid-pathway, fish consumption and the risk of colorectal cancer.

  International journal of cancer 20060715

• Surface proton donors for the D-pathway of cytochrome c oxidase in the absence of subunit III.

  Biochemistry 20060711

• Effect of inhibition of nitric oxide synthase on renal cyclooxygenase in the diabetic rat.

  European journal of pharmacology 20060710

• Alpha-bulnesene, a novel PAF receptor antagonist isolated from Pogostemon cablin.

  Biochemical and biophysical research communications 20060707

• Mechanism of induction of muscle protein degradation by angiotensin II.

  Cellular signalling 20060701

• Potentiation of TRPV3 channel function by unsaturated fatty acids.

  Journal of cellular physiology 20060701

• Formation of Nepsilon-(succinyl)lysine in vivo: a novel marker for docosahexaenoic acid-derived protein modification.

  Journal of lipid research 20060701

• Receptor-independent actions of cannabinoids on cell membranes: focus on endocannabinoids.

  Pharmacology & therapeutics 20060701

• Arachidonic acid cascade and epithelial barrier function during Caco-2 cell differentiation.

  Journal of lipid research 20060701

• Soluble oligomers of amyloid-beta peptide induce neuronal apoptosis by activating a cPLA2-dependent sphingomyelinase-ceramide pathway.

  Neurobiology of disease 20060701

• Krabbe disease: psychosine-mediated activation of phospholipase A2 in oligodendrocyte cell death.

  Journal of lipid research 20060701

• Prostaglandin production by human osteoclasts in culture.

  The Journal of rheumatology 20060701

• Identification and characterization of a collagen-induced platelet aggregation inhibitor, triplatin, from salivary glands of the assassin bug, Triatoma infestans.

  The FEBS journal 20060701

• Arachidonic acid induces augmented vasoconstriction via cyclooxygenase 1 in the aorta from rats fed a high-fat diet.

  Prostaglandins, leukotrienes, and essential fatty acids 20060701

• Transcellular secretion of group V phospholipase A2 from epithelium induces beta 2-integrin-mediated adhesion and synthesis of leukotriene C4 in eosinophils.

  Journal of immunology (Baltimore, Md. : 1950) 20060701

• Myocardial protection using an omega-3 fatty acid infusion: quantification and mechanism of action.

  The Journal of thoracic and cardiovascular surgery 20060701

• Nutritional approach to restore impaired intestinal barrier function and growth after neonatal stress in rats.

  Journal of pediatric gastroenterology and nutrition 20060701

• Modulation of ACTH-induced cortisol release by polyunsaturated fatty acids in interrenal cells from gilthead seabream, Sparus aurata.

  The Journal of endocrinology 20060701

• Mechanisms of cell volume regulation in hypo-osmolality.

  The American journal of medicine 20060701

• Oxidative alterations of cyclooxygenase during atherogenesis.

  Prostaglandins & other lipid mediators 20060701

• Metabolic mechanisms in the pathogenesis of osteoarthritis. A review.

  The journal of knee surgery 20060701

• [Arachidonate metabolites].

  Nihon rinsho. Japanese journal of clinical medicine 20060701

• Supplementation of n-3 fatty acids during pregnancy and lactation reduces maternal plasma lipid levels and provides DHA to the infants.

  The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 20060701

• Neuroprotection of rat hippocampal slices exposed to oxygen-glucose deprivation by enrichment with docosahexaenoic acid and by inhibition of hydrolysis of docosahexaenoic acid-containing phospholipids by calcium independent phospholipase A2.

  Neuroscience 20060630

• Design, synthesis, and structure-activity relationships of thieno[2,3-b]pyridin-4-one derivatives as a novel class of potent, orally active, non-peptide luteinizing hormone-releasing hormone receptor antagonists.

  Journal of medicinal chemistry 20060629

• Residual arachidonic acid-induced platelet activation via an adenosine diphosphate-dependent but cyclooxygenase-1- and cyclooxygenase-2-independent pathway: a 700-patient study of aspirin resistance.

  Circulation 20060627

• Enhancement of arachidonic acid signaling pathway by nicotinic acid receptor HM74A.

  Biochemical and biophysical research communications 20060623

• Intracellular actions of group IIA secreted phospholipase A2 and group IVA cytosolic phospholipase A2 contribute to arachidonic acid release and prostaglandin production in rat gastric mucosal cells and transfected human embryonic kidney cells.

  The Journal of biological chemistry 20060616

• Anti-platelet effects of bioactive compounds isolated from the bark of Rhus verniciflua Stokes.

  Journal of ethnopharmacology 20060615

• ABCA1-dependent but apoA-I-independent cholesterol efflux mediated by fatty acid-bile acid conjugates (FABACs).

  The Biochemical journal 20060615

• Increased expression of cyclooxygenase-2 mediates enhanced contraction to endothelin ETA receptor stimulation in endothelial nitric oxide synthase knockout mice.

  Circulation research 20060609

• Acyl-CoA synthetase activity links wild-type but not mutant alpha-synuclein to brain arachidonate metabolism.

  Biochemistry 20060606

• Volume regulation following hyposmotic shock in isolated turbot (Scophthalmus maximus) hepatocytes.

  Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20060601

• Cyclooxygenase blockade attenuates responses of group III and IV muscle afferents to dynamic exercise in cats.

  American journal of physiology. Heart and circulatory physiology 20060601

• PPAR-alpha activator fenofibrate increases renal CYP-derived eicosanoid synthesis and improves endothelial dilator function in obese Zucker rats.

  American journal of physiology. Heart and circulatory physiology 20060601

• Potentiation of native and recombinant P2X7-mediated calcium signaling by arachidonic acid in cultured cortical astrocytes and human embryonic kidney 293 cells.

  Molecular pharmacology 20060601

• Lipid remodeling of murine epididymosomes and spermatozoa during epididymal maturation.

  Biology of reproduction 20060601

• Uptake and metabolism of plasma-derived erucic acid by rat brain.

  Journal of lipid research 20060601

• Cytoglobin overexpression protects against damage-induced fibrosis.

  Molecular therapy : the journal of the American Society of Gene Therapy 20060601

• The role of phospholipases A2 in schizophrenia.

  Molecular psychiatry 20060601

• A light scattering assay for arachidonic acid-induced tau fibrillization without interfering micellization.

  Analytical biochemistry 20060601

• Arachidonic acid is a physiological activator of the ryanodine receptor in pancreatic beta-cells.

  Cell calcium 20060601

• Protein tyrosine phosphatases regulate arachidonic acid release, StAR induction and steroidogenesis acting on a hormone-dependent arachidonic acid-preferring acyl-CoA synthetase.

  The Journal of steroid biochemistry and molecular biology 20060601

• Effect of n-3 and n-6 polyunsaturated fatty acids on lymphocyte proliferation, interleukin production and phospholipid fatty acids composition in type 2 diabetic and healthy subjects in Jordan people.

  Prostaglandins, leukotrienes, and essential fatty acids 20060601

• Evidence for chemicals sensitizing discharge from skeletal muscle afferents supporting cardiorespiratory reflexes during simulated exercise.

  American journal of physiology. Heart and circulatory physiology 20060601

• Antioxidative and acute antiinflammatory effects of Torreya grandis.

  Fitoterapia 20060601

• Arachidonic acid suppresses growth of human lung tumor A549 cells through down-regulation of ALDH3A1 expression.

  Free radical biology & medicine 20060601

• Protective effects of a standard extract of Mangifera indica L. (VIMANG) against mouse ear edemas and its inhibition of eicosanoid production in J774 murine macrophages.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20060601

• Participation of epoxygenase activation in saikogenin D-induced inhibition of prostaglandin E(2) synthesis.

  The Journal of pharmacy and pharmacology 20060601

• Divergent cyclooxygenase responses to fatty acid structure and peroxide level in fish and mammalian prostaglandin H synthases.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060601

• Arachidonic acid pathways in nociception.

  The journal of supportive oncology 20060601

• Hypercapnia- and trans-arachidonic acid-induced retinal microvascular degeneration: implications in the genesis of retinopathy of prematurity.

  Seminars in perinatology 20060601

• The effect of acteoside on histamine release and arachidonic acid release in RBL-2H3 mast cells.

  Archives of pharmacal research 20060601

• Novel chemical mediators in the resolution of inflammation: resolvins and protectins.

  Anesthesiology clinics 20060601

• Impact of 20:4n-6 supplementation on the fatty acid composition and hemocyte parameters of the Pacific oyster Crassostrea gigas.

  Lipids 20060601

• Transcription factor Nrf2 protects HepG2 cells against CYP2E1 plus arachidonic acid-dependent toxicity.

  The Journal of biological chemistry 20060526

• Monochloramine potently inhibits arachidonic acid metabolism in rat platelets.

  Biochemical and biophysical research communications 20060526

• Expression of 5-lipoxygenase and leukotriene A4 hydrolase in human atherosclerotic lesions correlates with symptoms of plaque instability.

  Proceedings of the National Academy of Sciences of the United States of America 20060523

• Formation of F-ring isoprostane-like compounds (F3-isoprostanes) in vivo from eicosapentaenoic acid.

  The Journal of biological chemistry 20060519

• alpha(2)-Adrenergic receptors activate MAPK and Akt through a pathway involving arachidonic acid metabolism by cytochrome P450-dependent epoxygenase, matrix metalloproteinase activation and subtype-specific transactivation of EGFR.

  Cellular signalling 20060501

• Adenosine inhibits ENaC via cytochrome P-450 epoxygenase-dependent metabolites of arachidonic acid.

  American journal of physiology. Renal physiology 20060501

• Pharmacological characterization of 2NTX-99 [4-methoxy-N1-(4-trans-nitrooxycyclohexyl)-N3-(3-pyridinylmethyl)-1,3-benzenedicarboxamide], a potential antiatherothrombotic agent with antithromboxane and nitric oxide donor activity in platelet and vascular preparations.

  The Journal of pharmacology and experimental therapeutics 20060501

• Adenosine regulation of cystic fibrosis transmembrane conductance regulator through prostenoids in airway epithelia.

  American journal of respiratory cell and molecular biology 20060501

• Specific monocyte adhesion to endothelial cells induced by oxidized phospholipids involves activation of cPLA2 and lipoxygenase.

  Journal of lipid research 20060501

• PPARalpha activators and fasting induce the expression of adipose differentiation-related protein in liver.

  Journal of lipid research 20060501

• Mechanisms of aspirin sensitivity.

  Current allergy and asthma reports 20060501

• Arachidonic acid induces ERK activation via Src SH2 domain association with the epidermal growth factor receptor.

  Kidney international 20060501

• Activation of 5-lipoxygenase after oxygen-glucose deprivation is partly mediated via NMDA receptor in rat cortical neurons.

  Journal of neurochemistry 20060501

• Emerging role of epoxyeicosatrienoic acids in coronary vascular function.

  European journal of clinical investigation 20060501

• The regulation of formation of prostaglandins and arachidonoyl-CoA from arachidonic acid in rabbit kidney medulla microsomes by linoleic acid hydroperoxide.

  Prostaglandins & other lipid mediators 20060501

• Anti-inflammatory activity of Ailanthus altissima in ovalbumin-induced lung inflammation.

  Biological & pharmaceutical bulletin 20060501

• The anti-inflammatory and anti-nociceptive effects of ethyl acetate fraction of cynanchi paniculati radix.

  Biological & pharmaceutical bulletin 20060501

• Oxidative modulation of the transient potassium current IA by intracellular arachidonic acid in rat CA1 pyramidal neurons.

  The European journal of neuroscience 20060501

• Major enzymatic pathways in dermal wound healing: current understanding and future therapeutic targets.

  Current opinion in investigational drugs (London, England : 2000) 20060501

• Synthetic curcuminoids modulate the arachidonic acid metabolism of human platelet 12-lipoxygenase and reduce sprout formation of human endothelial cells.

  Molecular cancer therapeutics 20060501

• Antiplatelet activity of [5-(2-methoxy-5-chlorophenyl)furan-2-ylcarbonyl]guanidine (KR-32570), a novel sodium/hydrogen exchanger-1 and its mechanism of action.

  Archives of pharmacal research 20060501

• Differential effects of modulation of docosahexaenoic acid content during development in specific regions of rat brain.

  Lipids 20060501

• Year-round high arachidonic acid levels in herbivorous rabbit fish Siganus fuscescens tissues.

  Lipids 20060501

• Omega-3 fatty acids improve recovery, whereas omega-6 fatty acids worsen outcome, after spinal cord injury in the adult rat.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20060426

• Systematic evaluation of transcellular activities of secretory phospholipases A2. High activity of group V phospholipases A2 to induce eicosanoid biosynthesis in neighboring inflammatory cells.

  The Journal of biological chemistry 20060421

• Radical scavenger can scavenge lipid allyl radicals complexed with lipoxygenase at lower oxygen content.

  The Biochemical journal 20060415

• Peroxisome proliferator-activated receptor alpha agonist, clofibrate, has profound influence on myocardial fatty acid composition.

  Chemico-biological interactions 20060415

• Effect of arachidonic acid reacylation on leukotriene biosynthesis in human neutrophils stimulated with granulocyte-macrophage colony-stimulating factor and formyl-methionyl-leucyl-phenylalanine.

  The Journal of biological chemistry 20060414

• Monitoring of intercellular messengers released from neuron networks cultured in a microchip.

  Journal of chromatography. A 20060414

• Endothelial dysfunction and hypertension in rats transduced with CYP4A2 adenovirus.

  Circulation research 20060414

• Molecular mechanisms of PKCalpha localization and activation by arachidonic acid. The C2 domain also plays a role.

  Journal of molecular biology 20060407

• Omega-3 and omega-6 fatty acids stimulate cell membrane expansion by acting on syntaxin 3.

  Nature 20060406

• Chronic administration of ethyl docosahexaenoate reduces gerbil brain eicosanoid productions following ischemia and reperfusion.

  The Journal of nutritional biochemistry 20060401

• Effect of fast-food Mediterranean-type diet on type 2 diabetics and healthy human subjects' platelet aggregation.

  Diabetes research and clinical practice 20060401

• Involvement of phospholipase A2 in Pseudomonas aeruginosa-mediated PMN transepithelial migration.

  American journal of physiology. Lung cellular and molecular physiology 20060401

• 9L gliosarcoma cell proliferation and tumor growth in rats are suppressed by N-hydroxy-N'-(4-butyl-2-methylphenol) formamidine (HET0016), a selective inhibitor of CYP4A.

  The Journal of pharmacology and experimental therapeutics 20060401

• Involvement of cAMP-response element binding protein-1 in arachidonic acid-induced vascular smooth muscle cell motility.

  Journal of lipid research 20060401

• Cyclooxygenase isozymes are expressed in human myeloma cells but not involved in anti-proliferative effect of cyclooxygenase inhibitors.

  Molecular carcinogenesis 20060401

• Postmortem brain fatty acid profile of levodopa-treated Parkinson disease patients and parkinsonian monkeys.

  Neurochemistry international 20060401

• sPLA2-X stimulates cutaneous melanocyte dendricity and pigmentation through a lysophosphatidylcholine-dependent mechanism.

  The Journal of investigative dermatology 20060401

• Effects of amino acid on morphological development and nucleus formation of arachidonic acid-producing filamentous micro-organism, Mortierella alpina.

  Journal of applied microbiology 20060401

• Targeting PGE2 receptor subtypes rather than cyclooxygenases: a bridge over troubled water?

  Molecular interventions 20060401

• Dose- and time-dependent antiplatelet effects of aspirin.

  Thrombosis and haemostasis 20060401

• Lipid mediators: lipoxin and aspirin-triggered 15-epi-lipoxins.

  Inflammation & allergy drug targets 20060401

• Cellular, molecular, and tissue-level reactions to orthodontic force.

  American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics 20060401

• Formula supplemented with docosahexaenoic acid (DHA) and arachidonic acid (ARA): a critical review of the research.

  Journal for specialists in pediatric nursing : JSPN 20060401

• Oxidative stress and arachidonic acid mobilization.

  Biochimica et biophysica acta 20060401

• Binding investigation of human 5-lipoxygenase with its inhibitors by SPR technology correlating with molecular docking simulation.

  Journal of biochemistry 20060401

• Regulation of nerve growth factor induced histamine and arachidonic acid release from rat mast cells by cannabinoids.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20060401

• Bioactive lipids in schizophrenia.

  International review of psychiatry (Abingdon, England) 20060401

• Gestational diabetes mellitus enhances arachidonic and docosahexaenoic acids in placental phospholipids.

  Lipids 20060401

• Effect of temperature on the fatty acid composition and temporal trajectories of fatty acids in fasting Daphnia pulex (Crustacea, Cladocera).

  Lipids 20060401

• Promotion of prostatic metastatic migration towards human bone marrow stoma by Omega 6 and its inhibition by Omega 3 PUFAs.

  British journal of cancer 20060327

• An endogenous acid-sensitive K+ channel expressed in COS-7 cells.

  Biochemical and biophysical research communications 20060324

• Sex differences in platelet reactivity and response to low-dose aspirin therapy.

  JAMA 20060322

• Affinity labeling of the rabbit 12/15-lipoxygenase using azido derivatives of arachidonic acid.

  Biochemistry 20060321

• Ceramide-1-phosphate activates cytosolic phospholipase A2alpha directly and by PKC pathway.

  Biochemical pharmacology 20060314

• Molecular dynamics simulations of arachidonic acid complexes with COX-1 and COX-2: insights into equilibrium behavior.

  Biochemistry 20060314

• Molecular dynamics simulations of arachidonic acid-derived pentadienyl radical intermediate complexes with COX-1 and COX-2: insights into oxygenation regio- and stereoselectivity.

  Biochemistry 20060314

• Tumor-specific expression of the novel cytochrome P450 enzyme, CYP2W1.

  Biochemical and biophysical research communications 20060310

• Feed forward cycle of hypotonic stress-induced ATP release, purinergic receptor activation, and growth stimulation of prostate cancer cells.

  The Journal of biological chemistry 20060303

• Overexpression of cytosolic group IVA phospholipase A2 protects cells from Ca2+-dependent death.

  The Journal of biological chemistry 20060303

• Regulation of cytosolic phospholipase A2 activation and cyclooxygenase 2 expression in macrophages by the beta-glucan receptor.

  The Journal of biological chemistry 20060303

• Subchronic (13-week) oral toxicity study, preceded by an in utero exposure phase, with arachidonate-enriched triglyceride oil (SUNTGA40S) in rats.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20060301

• Chronic carbamazepine decreases the incorporation rate and turnover of arachidonic acid but not docosahexaenoic acid in brain phospholipids of the unanesthetized rat: relevance to bipolar disorder.

  Biological psychiatry 20060301

• Positive cooperativity between the thrombin and bradykinin B2 receptors enhances arachidonic acid release.

  American journal of physiology. Heart and circulatory physiology 20060301

• Fatty acid relationships in former cannabis users with schizophrenia.

  Progress in neuro-psychopharmacology & biological psychiatry 20060301

• Maternal dietary fat alters amniotic fluid and fetal intestinal membrane essential n-6 and n-3 fatty acids in the rat.

  American journal of physiology. Gastrointestinal and liver physiology 20060301

• Blockade of arachidonic acid incorporation into phospholipids induces apoptosis in U937 promonocytic cells.

  Journal of lipid research 20060301

• Sunlight generates multiple tryptophan photoproducts eliciting high efficacy CYP1A induction in chick hepatocytes and in vivo.

  Toxicological sciences : an official journal of the Society of Toxicology 20060301

• Synthesis of long-chain polyunsaturated fatty acids in lactating mammary gland: role of Delta5 and Delta6 desaturases, SREBP-1, PPARalpha, and PGC-1.

  Journal of lipid research 20060301

• Differential effect of saturated, monounsaturated, and polyunsaturated fatty acids on alloxan-induced diabetes mellitus.

  Prostaglandins, leukotrienes, and essential fatty acids 20060301

• Anti-platelet activity of KR-32560, a novel sodium/hydrogen exchanger-1 inhibitor.

  Pharmacological research 20060301

• Benefits of prolonged gradient separation for high-performance liquid chromatography-tandem mass spectrometry quantitation of plasma total 15-series F-isoprostanes.

  Analytical biochemistry 20060301

• The presynaptic effects of arachidonic acid and prostaglandin E2 at the frog neuromuscular junction.

  Neuroscience and behavioral physiology 20060301

• Effect of alcohol on cytochrome p450 arachidonic acid metabolism and blood pressure in rats and its modulation by red wine polyphenolics.

  Clinical and experimental pharmacology & physiology 20060301

• Fatty acids in serum cholesteryl esters in relation to asthma and lung function in children.

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20060301

• Diabetes alters osmotic swelling characteristics and membrane conductance of glial cells in rat retina.

  Diabetes 20060301

• New insights into endocannabinoid degradation and its therapeutic potential.

  Mini reviews in medicinal chemistry 20060301

• Docosahexaenoic acid in red blood cells of term infants receiving two levels of long-chain polyunsaturated fatty acids.

  Journal of pediatric gastroenterology and nutrition 20060301

• The stereospecific triacylglycerol structures and Fatty Acid profiles of human milk and infant formulas.

  Journal of pediatric gastroenterology and nutrition 20060301

• [Recent advances in the study of arachidonic acid-sensitive and mechano-gated tandem-pore-domain potassium channels--TREK].

  Yao xue xue bao = Acta pharmaceutica Sinica 20060301

• Prolyl endopeptidase inhibitory activity of unsaturated fatty acids.

  Journal of agricultural and food chemistry 20060222

• Mechanisms of antiplatelet activity of PC-09, a newly synthesized pyridazinone derivative.

  European journal of pharmacology 20060217

• Antiobesity-like effects of the 5-HT2C receptor agonist WAY-161503.

  Brain research 20060216

• Arachidonic acid induces specific membrane permeability increase in heart mitochondria.

  FEBS letters 20060206

• Synthesis of the enediol isofurans, endogenous oxidation products of arachidonic acid.

  The Journal of organic chemistry 20060203

• Modulation of arachidonic acid metabolism and nitric oxide synthesis by garcinol and its derivatives.

  Carcinogenesis 20060201

• Effects of selective inhibition of cytochrome P-450 omega-hydroxylases and ischemic preconditioning in myocardial protection.

  American journal of physiology. Heart and circulatory physiology 20060201

• Oxymetazoline inhibits proinflammatory reactions: effect on arachidonic acid-derived metabolites.

  The Journal of pharmacology and experimental therapeutics 20060201

• Nongenomic action of progesterone inhibits oxytocin-induced phosphoinositide hydrolysis and prostaglandin F2alpha secretion in the ovine endometrium.

  Endocrinology 20060201

• Agonists-induced platelet activation varies considerably in healthy male individuals: studies by flow cytometry.

  Annals of hematology 20060201

• Prostaglandin D2 mediates neuronal damage by amyloid-beta or prions which activates microglial cells.

  Neuropharmacology 20060201

• Implications of oxidative stress in the cytotoxicity of Pseudomonas aeruginosa ExoU.

  Microbes and infection 20060201

• Presynaptic effects of anandamide and WIN55,212-2 on glutamatergic nerve endings isolated from rat hippocampus.

  Neurochemistry international 20060201

• Effects of antiflammins on transglutaminase and phospholipase A2 activation by transglutaminase.

  International immunopharmacology 20060201

• Coxibs and Alzheimer's disease: should they stay or should they go?

  Annals of neurology 20060201

• Inhibitory effects of black tea theaflavin derivatives on 12-O-tetradecanoylphorbol-13-acetate-induced inflammation and arachidonic acid metabolism in mouse ears.

  Molecular nutrition & food research 20060201

• Resting and arecoline-stimulated brain metabolism and signaling involving arachidonic acid are altered in the cyclooxygenase-2 knockout mouse.

  Journal of neurochemistry 20060201

• Effect of five triterpenoid compounds isolated from root bark of Aralia elata on stimulus-induced superoxide generation, tyrosyl or serine/threonine phosphorylation and translocation of p47(phox), p67(phox), and rac to cell membrane in human neutrophils.

  Archives of biochemistry and biophysics 20060201

• Cholesterol and its anionic derivatives inhibit 5-lipoxygenase activation in polymorphonuclear leukocytes and MonoMac6 cells.

  The FEBS journal 20060201

• Prostaglandin-H-synthase (PGHS)-1 and -2 microtiter assays for the testing of herbal drugs and in vitro inhibition of PGHS-isoenzyms by polyunsaturated fatty acids from Platycodi radix.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20060201

• Abnormal fatty acid profiles occur in atopic dermatitis but what do they mean?

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20060201

• Platelet ADP response deteriorates in synthetic storage media.

  Transfusion 20060201

• Role of cytochrome P450 in phospholipase A2- and arachidonic acid-mediated cytotoxicity.

  Free radical biology & medicine 20060201

• Phospholipase A2, reactive oxygen species, and lipid peroxidation in cerebral ischemia.

  Free radical biology & medicine 20060201

• Cyclooxygenase products stimulate carbon monoxide production by piglet cerebral microvessels.

  Experimental biology and medicine (Maywood, N.J.) 20060201

• Arachidonic acid activates phosphatidylinositol 3-kinase signaling and induces gene expression in prostate cancer.

  Cancer research 20060201

• Dietary vitamin and lipid therapy rescues aberrant signaling and apoptosis and prevents hyperglycemia-induced diabetic embryopathy in rats.

  American journal of obstetrics and gynecology 20060201

• Effect of geraniol on fatty-acid and mevalonate metabolism in the human hepatoma cell line Hep G2.

  Biochemistry and cell biology = Biochimie et biologie cellulaire 20060201

• The role of COX-2 inhibitors in the perioperative setting: efficacy and safety--a systematic review.

  AANA journal 20060201

• Biological basis and clinical implications of acetylsalicylic acid resistance.

  The Canadian journal of cardiology 20060201

• Polymorphisms of COX-1 and GPVI associate with the antiplatelet effect of aspirin in coronary artery disease patients.

  Thrombosis and haemostasis 20060201

• Contribution of lipid mediators to the regulation of phosphatidylcholine synthesis by angiotensin.

  Biochimica et biophysica acta 20060201

• Effect of docosahexaenoic acid administration on plasma lipid profile and metabolic parameters of children with methylmalonic acidaemia.

  Journal of inherited metabolic disease 20060201

• Short-term and long-term effects of fatty acids in rat hepatoma AS-30D cells: the way to apoptosis.

  Biochimica et biophysica acta 20060201

• Effects of arachidonic acid on the lysosomal ion permeability and osmotic stability.

  Journal of bioenergetics and biomembranes 20060201

• Selective incorporation of docosahexaenoic acid into lysobisphosphatidic acid in cultured THP-1 macrophages.

  Lipids 20060201

• Convergent oxygenation of arachidonic acid by 5-lipoxygenase and cyclooxygenase-2.

  Journal of the American Chemical Society 20060125

• FcepsilonR1 and toll-like receptors mediate synergistic signals to markedly augment production of inflammatory cytokines in murine mast cells.

  Blood 20060115

• Involvement of arachidonic acid metabolism and EGF receptor in neurotensin-induced prostate cancer PC3 cell growth.

  Regulatory peptides 20060115

• Isolation and functional characterization of fatty acid delta5-elongase gene from the liverwort Marchantia polymorpha L.

  FEBS letters 20060109

• Arachidonic acid regulates the translocation of 5-lipoxygenase to the nuclear membranes in human neutrophils.

  The Journal of biological chemistry 20060106

• Effects of stable suppression of Group VIA phospholipase A2 expression on phospholipid content and composition, insulin secretion, and proliferation of INS-1 insulinoma cells.

  The Journal of biological chemistry 20060106

• Role of insulin on PGE2 generation during LPS-induced lung inflammation in rats.

  Life sciences 20060102

• Role of phospholipase C and diacylglyceride lipase pathway in arachidonic acid release and acetylcholine-induced vascular relaxation in rabbit aorta.

  American journal of physiology. Heart and circulatory physiology 20060101

• 5-Lipoxygenase-activating protein homodimer in human neutrophils: evidence for a role in leukotriene biosynthesis.

  The Biochemical journal 20060101

• Altered arachidonic acid metabolism impairs functional vasodilation in metabolic syndrome.

  American journal of physiology. Regulatory, integrative and comparative physiology 20060101

• Identifying and defusing weapons of mass inflammation in carcinogenesis.

  Biochimica et biophysica acta 20060101

• A biosynthetic pathway generating 12-hydroxy-5,8,14-eicosatrienoic acid from arachidonic acid is active in mouse skin microsomes.

  The Journal of pharmacology and experimental therapeutics 20060101

• Chronic ethanol consumption enhances phenylephrine-induced contraction in the isolated rat aorta.

  The Journal of pharmacology and experimental therapeutics 20060101

• Characterization of genes for novel thaumatin-like proteins in Cryptomeria japonica.

  Tree physiology 20060101

• New metabolically stable fatty acid amide ligands of cannabinoid receptors: Synthesis and receptor affinity studies.

  Bioorganic & medicinal chemistry letters 20060101

• Role of human cyclooxygenase-2 in the bioactivation of dapsone and sulfamethoxazole.

  Drug metabolism and disposition: the biological fate of chemicals 20060101

• Nitric oxide alters arachidonic acid turnover in brain cortex synaptoneurosomes.

  Neurochemistry international 20060101

• Eugenol--the active principle from cloves inhibits 5-lipoxygenase activity and leukotriene-C4 in human PMNL cells.

  Prostaglandins, leukotrienes, and essential fatty acids 20060101

• Bioavailability and safety of a high dose of docosahexaenoic acid triacylglycerol of algal origin in cystic fibrosis patients: a randomized, controlled study.

  Nutrition (Burbank, Los Angeles County, Calif.) 20060101

• The stretch-activated potassium channel TREK-1 in rat cardiac ventricular muscle.

  Cardiovascular research 20060101

• Differential effects of fexofenadine on arachidonic acid metabolism in cultured human monocytes.

  Pharmacology 20060101

• Enhancement of Ca2+-regulated exocytosis by indomethacin in guinea-pig antral mucous cells: arachidonic acid accumulation.

  Experimental physiology 20060101

• Impaired NADPH oxidase activity in Rac2-deficient murine neutrophils does not result from defective translocation of p47phox and p67phox and can be rescued by exogenous arachidonic acid.

  Journal of leukocyte biology 20060101

• Effects of different aspirin formulations on platelet aggregation times and on plasma salicylate concentrations.

  Thrombosis research 20060101

• Identification and characterization of an arachidonate 11R-lipoxygenase.

  Archives of biochemistry and biophysics 20060101

• Valproic acid selectively inhibits conversion of arachidonic acid to arachidonoyl-CoA by brain microsomal long-chain fatty acyl-CoA synthetases: relevance to bipolar disorder.

  Psychopharmacology 20060101

• A circadian rhythm-regulated tomato gene is induced by Arachidonic acid and Phythophthora infestans infection.

  Plant physiology 20060101

• Free arachidonic versus eicosapentaenoic acid differentially influences the potency of bacterial exotoxins to provoke myocardial depression in isolated rat hearts.

  Critical care medicine 20060101

• Current and future status of prostate cancer chemoprevention.

  Expert review of anticancer therapy 20060101

• Arachidonic acid metabolites mediate the radiation-induced increase in glomerular albumin permeability.

  Experimental biology and medicine (Maywood, N.J.) 20060101

• Enzymes involved in the biosynthesis of leukotriene B4 and prostaglandin E2 are active in sebaceous glands.

  Journal of molecular medicine (Berlin, Germany) 20060101

• Prostaglandins, bioassay and inflammation.

  British journal of pharmacology 20060101

• Lipid signaling changes in smooth muscle remodeling associated with partial urinary bladder outlet obstruction.

  Neurourology and urodynamics 20060101

• Fatty acid composition of skeletal muscle and adipose tissue in Spanish infants and children.

  The British journal of nutrition 20060101

• Regulation of Akt by arachidonic acid and phosphoinositide 3-kinase in angiotensin II-stimulated vascular smooth muscle cells.

  Biochimica et biophysica acta 20060101

• 5-Lipoxygenase, leukotrienes biosynthesis and potential antileukotrienic agents.

  Current medicinal chemistry 20060101

• Blockade of arachidonic acid pathway induces sprouting in the adult but not in the neonatal uncrossed retinotectal projection.

  Neuroscience 20060101

• Systemic blood pressure response to the inhibition of two hyperpolarizing pathways: a comparison to NO-synthase inhibition.

  Physiological research 20060101

• Phospholipid fatty acid composition and diamine oxidase activity of intestinal mucosa from rats treated with irinotecan hydrochloride (CPT-11) under vegetable oil-enriched diets: comparison between perilla oil and corn oil.

  JPEN. Journal of parenteral and enteral nutrition 20060101

• The isoprostanes - unique products of arachidonate peroxidation: their role as mediators of oxidant stress.

  Current pharmaceutical design 20060101

• Cyclooxygenase expression is not required for release of arachidonic acid from cells by some nonsteroidal anti-inflammatory drugs and cancer preventive agents.

  BMC pharmacology 20060101

• Metabolism of arachidonic acid to eicosanoids within the nucleus.

  Biochimica et biophysica acta 20060101

• [Metabolites of arachidonic acid in activating platelets and their estimation by radionuclide techniques].

  Hellenic journal of nuclear medicine 20060101

• How dietary arachidonic- and docosahexaenoic- acid rich oils differentially affect the murine hepatic transcriptome.

  Lipids in health and disease 20060101

• Cytochromes P450--a family of proteins and scientists-understanding their relationships.

  Drug metabolism reviews 20060101

• CYP1A in TCDD toxicity and in physiology-with particular reference to CYP dependent arachidonic acid metabolism and other endogenous substrates.

  Drug metabolism reviews 20060101

• [Formation of reactive oxygen species in monocytes at adhesion to glass].

  Tsitologiia 20060101

• [Arachidonoyl amino acids and arachidonoyl peptides: synthesis and properties].

  Bioorganicheskaia khimiia 20060101

• New frontiers in the therapeutic management of transplant rejection.

  Current pharmaceutical design 20060101

• The composition of polyunsaturated fatty acids in erythrocytes of lactating mothers and their infants.

  Maternal & child nutrition 20060101

• Antiangiogenic effect of sulindac sulfide could be secondary to induction of apoptosis and cell cycle arrest.

  Anticancer research 20060101

• Metabolites of arachidonic acid in activating platelets and their estimation by radionuclide techniques.

  Hellenic journal of nuclear medicine 20060101

• Nociceptors in cardiovascular functions: complex interplay as a result of cyclooxygenase inhibition.

  Molecular pain 20060101

• Regulated spatial distribution of cyclooxygenases and lipoxygenases in Crohn's ulcer.

  Mediators of inflammation 20060101

• Arachidonic acid-dependent activation of a p22(phox)-based NAD(P)H oxidase mediates angiotensin II-induced mesangial cell protein synthesis and fibronectin expression via Akt/PKB.

  Antioxidants & redox signaling 20060101

• Effect of traditional Greek Mediterranean meals on platelet aggregation in normal subjects and in patients with type 2 diabetes mellitus.

  Journal of medicinal food 20060101

• New evidence of H1-receptor independent COX-2 inhibition by fexofenadine HCl in vitro.

  Pharmacology 20060101

• The effect of packed red blood cell storage on arachidonic acid and advanced glycation end-product formation.

  Archivum immunologiae et therapiae experimentalis 20060101

• [The role of COX-2 in dentistry. Past or future?].

  Schweizer Monatsschrift fur Zahnmedizin = Revue mensuelle suisse d'odonto-stomatologie = Rivista mensile svizzera di odontologia e stomatologia 20060101

• Incinerator fly ash provokes alteration of redox equilibrium and liberation of arachidonic acid in vitro.

  Biological chemistry 20060101

• Multiple PLA2 isoforms regulate taurine release in NIH3T3 mouse fibroblasts.

  Advances in experimental medicine and biology 20060101

• The quality properties and saturated and unsaturated fatty acid profiles of quail egg: the alterations of fatty acids with process effects.

  International journal of food sciences and nutrition 20060101

• Arachidonate and NADPH oxidase synergise with iNOS to induce death in macrophages: mechanisms of inflammatory degeneration.

  Pharmacological reports : PR 20060101

• Rantes potentiates human macrophage aggregation and activation responses to calcium ionophore (A23187) and activates arachidonic acid pathways.

  Journal of biological regulators and homeostatic agents 20060101

• Intracellular calcium, endothelial cells and angiogenesis.

  Recent patents on anti-cancer drug discovery 20060101

• Mobilization of arachidonyl moieties from triacylglycerols into chloroplastic lipids following recovery from nitrogen starvation of the microalga Parietochloris incisa.

  Biochimica et biophysica acta 20051230

• Regulation of cerebral microvascular endothelial cell cyclooxygenase-2 message and activity by blood derived vasoactive agents.

  Brain research bulletin 20051230

• Effects of arachidonic acid analogs on FcepsilonRI-mediated activation of mast cells.

  Biochimica et biophysica acta 20051230

• Polychlorinated biphenyls induce arachidonic acid release in human platelets in a tamoxifen sensitive manner via activation of group IVA cytosolic phospholipase A2-alpha.

  Biochemical pharmacology 20051219

• The cysteinyl-leukotriene-1 receptor antagonist zafirlukast is a potent secretagogue in rat and human airways.

  European journal of pharmacology 20051219

• 2-(2-Br-phenyl)-8-methoxy-benzoxazinone (HPW-RX2), a direct thrombin inhibitor with a suppressive effect on thromboxane formation in platelets.

  European journal of pharmacology 20051219

• Regulating leukotriene synthesis: the role of nuclear 5-lipoxygenase.

  Journal of cellular biochemistry 20051215

• Role of Bcl-2 in the arachidonate-mediated survival signaling preventing mitochondrial permeability transition-dependent U937 cell necrosis induced by peroxynitrite.

  Free radical biology & medicine 20051215

• Cyclooxygenase-2 inhibition sensitizes human colon carcinoma cells to TRAIL-induced apoptosis through clustering of DR5 and concentrating death-inducing signaling complex components into ceramide-enriched caveolae.

  Cancer research 20051215

• Synthesis of 8,9-leukotriene A4 by murine 8-lipoxygenase.

  Biochemical and biophysical research communications 20051209

• Arachidonate 12-lipoxygenases with reference to their selective inhibitors.

  Biochemical and biophysical research communications 20051209

• Arachidonic acid inhibits the insulin induction of glucose-6-phosphate dehydrogenase via p38 MAP kinase.

  The Journal of biological chemistry 20051209

• RSV-induced prostaglandin E2 production occurs via cPLA2 activation: role in viral replication.

  Virology 20051205

• Do arachidonic acid and its metabolites, secreted by rheumatoid and osteoarthritic synovial tissue, account for the strong inhibition of DNA synthesis in cultured human articular chondrocytes? A novel approach to the mechanism of tissue damage.

  Joint, bone, spine : revue du rhumatisme 20051201

• Progesterone primes zona pellucida-induced activation of phospholipase A2 during acrosomal exocytosis in guinea pig spermatozoa.

  Journal of cellular physiology 20051201

• Cytochrome P-450-dependent metabolism of arachidonic acid in the kidney of rats with diabetes insipidus.

  American journal of physiology. Renal physiology 20051201

• Fenamates and diltiazem modulate lipid-sensitive mechano-gated 2P domain K(+) channels.

  Pflugers Archiv : European journal of physiology 20051201

• Potential role for mast cell tryptase in recruitment of inflammatory cells to endothelium.

  American journal of physiology. Cell physiology 20051201

• Inhibitory effect of the Korean herbal medicine, Dae-Jo-Whan, on platelet-activating factor-induced platelet aggregation.

  Journal of ethnopharmacology 20051201

• Cloning, expression, and functional characterization of human cyclooxygenase-1 splicing variants: evidence for intron 1 retention.

  The Journal of pharmacology and experimental therapeutics 20051201

• Differential effects of COX inhibitors against beta-amyloid-induced neurotoxicity in human neuroblastoma cells.

  Neurochemistry international 20051201

• Inhibitors of arachidonic acid metabolism act synergistically to signal apoptosis in neoplastic cells.

  Prostaglandins, leukotrienes, and essential fatty acids 20051201

• Effects of endocrine disruptors on the formation of prostaglandin and arachidonoyl-CoA formed from arachidonic acid in rabbit kidney medulla microsomes.

  Prostaglandins, leukotrienes, and essential fatty acids 20051201

• Stimulation of prostaglandin E2 (PGE2) production by arachidonic acid, oestrogen and parathyroid hormone in MG-63 and MC3T3-E1 osteoblast-like cells.

  Prostaglandins, leukotrienes, and essential fatty acids 20051201

• Regulation of noncapacitative calcium entry by arachidonic acid and nitric oxide in endothelial cells.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20051201

• Modification of eicosanoid profile in human blood treated by dual COX/LOX inhibitors.

  Prostaglandins, leukotrienes, and essential fatty acids 20051201

• Long-chain polyunsaturated fatty acids protect the heart against ischemia/reperfusion-induced injury via a MAPK dependent pathway.

  Journal of molecular and cellular cardiology 20051201

• Suppression of arachidonic acid metabolism and nitric oxide formation by kudzu isoflavones in murine macrophages.

  Molecular nutrition & food research 20051201

• Increased scratching counts depend on a decrease in ability of cutaneous prostaglandin D2 biosynthesis in NC/Nga mice with atopic dermatitis.

  Experimental dermatology 20051201

• Effect of p47phox gene deletion on ROS production and oxygen sensing in mouse carotid body chemoreceptor cells.

  American journal of physiology. Lung cellular and molecular physiology 20051201

• Group IV cytosolic phospholipase A2 mediates arachidonic acid release in H9c2 rat cardiomyocyte cells in response to hydrogen peroxide.

  Prostaglandins & other lipid mediators 20051201

• Eicosanoid-mediated proinflammatory activity of Pseudomonas aeruginosa ExoU.

  Cellular microbiology 20051201

• Increase in heme oxygenase-1 levels ameliorates renovascular hypertension.

  Kidney international 20051201

• Linoleic acid, but not oleic acid, upregulates production of interleukin-8 by human vascular smooth muscle cells via arachidonic acid metabolites under conditions of oxidative stress.

  Journal of the Society for Gynecologic Investigation 20051201

• Topical analgesia for chest tube removal in cardiac patients.

  Journal of cardiothoracic and vascular anesthesia 20051201

• Effects of compounds in leaves of Salix matsudana on arachidonic acid metabolism.

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20051201

• Inducers and co-inducers of molecular chaperones.

  International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 20051201

• Eicosanoids.

  Critical care medicine 20051201

• Enhanced antiplatelet effect of clopidogrel in patients whose platelets are least inhibited by aspirin: a randomized crossover trial.

  Journal of thrombosis and haemostasis : JTH 20051201

• Localization of rat cytochrome P450 in various tissues and comparison of arachidonic acid metabolism by rat P450 with that by human P450 orthologs.

  Drug metabolism and pharmacokinetics 20051201

• Lipoxygenase pathway of arachidonic acid metabolism in growth control of tumor cells of different type.

  Biochemistry. Biokhimiia 20051201

• Transformation of oil-producing fungus, Mortierella alpina 1S-4, using Zeocin, and application to arachidonic acid production.

  Journal of bioscience and bioengineering 20051201

• Activatory properties of lysophosphatidic acid on human THP-1 cells.

  Inflammation 20051201

• Chronic administration of ethyl docosahexaenoate decreases mortality and cerebral edema in ischemic gerbils.

  Life sciences 20051119

• On the relationships of substrate orientation, hydrogen abstraction, and product stereochemistry in single and double dioxygenations by soybean lipoxygenase-1 and its Ala542Gly mutant.

  The Journal of biological chemistry 20051118

• Regulation of tissue transglutaminase by prolonged increase of intracellular Ca2+, but not by initial peak of transient Ca2+ increase.

  Biochemical and biophysical research communications 20051118

• Separation and identification of F2-isoprostane regioisomers and diastereomers by novel liquid chromatographic/mass spectrometric methods.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20051115

• Relationship between plasma phospholipid polyunsaturated fatty acid composition and bone disease in renal transplantation.

  Transplantation 20051115

• Multiple signaling pathways regulating steroidogenesis and steroidogenic acute regulatory protein expression: more complicated than we thought.

  Molecular endocrinology (Baltimore, Md.) 20051101

• Reversal of delayed vasospasm by an inhibitor of the synthesis of 20-HETE.

  American journal of physiology. Heart and circulatory physiology 20051101

• {Omega}-3 and {omega}-6 polyunsaturated fatty acids block HERG channels.

  American journal of physiology. Cell physiology 20051101

• Cyclo-oxygenase-2 contributes to constitutive prostanoid production in rat kidney and brain.

  The Biochemical journal 20051101

• Curcumin suppresses interleukin 1beta-mediated microsomal prostaglandin E synthase 1 by altering early growth response gene 1 and other signaling pathways.

  The Journal of pharmacology and experimental therapeutics 20051101

• Human U251 glioma cell proliferation is suppressed by HET0016 [N-hydroxy-N'-(4-butyl-2-methylphenyl)formamidine], a selective inhibitor of CYP4A.

  The Journal of pharmacology and experimental therapeutics 20051101

• Peroxisome proliferator-activated receptor alpha is required for feedback regulation of highly unsaturated fatty acid synthesis.

  Journal of lipid research 20051101

• Quantification of lipid alkyl radicals trapped with nitroxyl radical via HPLC with postcolumn thermal decomposition.

  Journal of lipid research 20051101

• Late-gestation rat myometrial cells express multiple isoforms of phospholipase A2 that mediate PCB 50-induced release of arachidonic acid with coincident prostaglandin production.

  Toxicological sciences : an official journal of the Society of Toxicology 20051101

• Novel mechanism of vasodilation in inflammatory bowel disease.

  Arteriosclerosis, thrombosis, and vascular biology 20051101

• PGE2 release is independent of upregulation of Group V phospholipase A2 during long-term stimulation of P388D1 cells with LPS.

  Journal of lipid research 20051101

• Acquisition of plasmin activity and induction of arachidonic acid release by Streptococcus suis in contact with human brain microvascular endothelial cells.

  FEMS microbiology letters 20051101

• 5E, 8Z, 11Z, 14Z-eicosatetraenoic acid, a novel trans isomer of arachidonic acid, causes G1 phase arrest and induces apoptosis of HL-60 cells.

  International journal of oncology 20051101

• Systematic review: the chemoprevention of oesophageal adenocarcinoma.

  Alimentary pharmacology & therapeutics 20051101

• Intracellular signaling for vasoconstrictor coupling factor 6: novel function of beta-subunit of ATP synthase as receptor.

  Hypertension (Dallas, Tex. : 1979) 20051101

• Molecular alterations during development of esophageal adenocarcinoma.

  Journal of surgical oncology 20051101

• Three percent diclofenac in 2.5% hyaluronan gel in the treatment of actinic keratoses: a meta-analysis of the recent studies.

  Archives of dermatological research 20051101

• A secretory PLA2 associated with tobacco hornworm hemocyte membrane preparations acts in cellular immune reactions.

  Archives of insect biochemistry and physiology 20051101

• Effects of intrarenal administration of the cox-2 inhibitor parecoxib during porcine suprarenal aortic cross-clamping.

  Shock (Augusta, Ga.) 20051101

• Overestimation of platelet aspirin resistance detection by thrombelastograph platelet mapping and validation by conventional aggregometry using arachidonic acid stimulation.

  Journal of the American College of Cardiology 20051101

• Specificity of receptor-ligand interactions and their effect on dimerisation as observed by electrospray mass spectrometry: bile acids form stable adducts to the RXRalpha.

  Journal of mass spectrometry : JMS 20051101

• Cognitive and physiological effects of Omega-3 polyunsaturated fatty acid supplementation in healthy subjects.

  European journal of clinical investigation 20051101

• Secretory phospholipases A2 in inflammatory and allergic diseases: not just enzymes.

  The Journal of allergy and clinical immunology 20051101

• Winter urban air particles from Rome (Italy): effects on the monocytic-macrophagic RAW 264.7 cell line.

  Environmental research 20051101

• Molecular targets of dietary polyphenols with anti-inflammatory properties.

  Yonsei medical journal 20051031

• Unsaturated fatty acids phosphorylate and destabilize ABCA1 through a phospholipase D2 pathway.

  The Journal of biological chemistry 20051028

• Cyclopentenone isoprostanes inhibit the inflammatory response in macrophages.

  The Journal of biological chemistry 20051021

• Anti-oxidative and anti-inflammatory activities of two different species of a Chinese herb I-Tiao-Gung.

  Life sciences 20051014

• Free fatty acids repress the GLUT4 gene expression in cardiac muscle via novel response elements.

  The Journal of biological chemistry 20051014

• The action of PKA on smooth muscle myosin phosphorylation.

  Life sciences 20051007

• Vasoactive prostanoids are generated from arachidonic acid by COX-1 and COX-2 in the mouse.

  American journal of physiology. Heart and circulatory physiology 20051001

• Arachidonic acid mediates non-capacitative calcium entry evoked by CB1-cannabinoid receptor activation in DDT1 MF-2 smooth muscle cells.

  Journal of cellular physiology 20051001

• Non-COX-2 targets and cancer: expanding the molecular target repertoire of chemoprevention.

  Biochemical pharmacology 20051001

• Survival pathways triggered by peroxynitrite in cells belonging to the monocyte/macrophage lineage.

  Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20051001

• Chronic valproate does not alter the kinetics of docosahexaenoic acid within brain phospholipids of the unanesthetized rat.

  Psychopharmacology 20051001

• Cytochrome P450 and arachidonic acid metabolites: role in myocardial ischemia/reperfusion injury revisited.

  Cardiovascular research 20051001

• The effect of CYP2E1-dependent oxidant stress on activity of proteasomes in HepG2 cells.

  The Journal of pharmacology and experimental therapeutics 20051001

• Leukotriene B4 mediates p47phox phosphorylation and membrane translocation in polyunsaturated fatty acid-stimulated neutrophils.

  Journal of leukocyte biology 20051001

• Basal and induced sphingosine kinase 1 activity in A549 carcinoma cells: function in cell survival and IL-1beta and TNF-alpha induced production of inflammatory mediators.

  Cellular signalling 20051001

• Group IVC cytosolic phospholipase A2gamma is farnesylated and palmitoylated in mammalian cells.

  Journal of lipid research 20051001

• Induction of central signalling pathways and select functional effects in human platelets by beta-boswellic acid.

  British journal of pharmacology 20051001

• Modulation of the cannabinoid CB2 receptor in microglial cells in response to inflammatory stimuli.

  Journal of neurochemistry 20051001

• Cyclooxygenase-1 haplotype modulates platelet response to aspirin.

  Journal of thrombosis and haemostasis : JTH 20051001

• A normotriglyceridemic, low HDL-cholesterol phenotype is characterised by elevated oxidative stress and HDL particles with attenuated antioxidative activity.

  Atherosclerosis 20051001

• Lumiracoxib does not affect the ex vivo antiplatelet aggregation activity of low-dose aspirin in healthy subjects.

  Journal of clinical pharmacology 20051001

• Role of arachidonic acid in hyposmotic membrane stretch-induced increase in calcium-activated potassium currents in gastric myocytes.

  Acta pharmacologica Sinica 20051001

• Anti-inflammatory effect of germanium-concentrated yeast against paw oedema is related to the inhibition of arachidonic acid release and prostaglandin E production in RBL 2H3 cells.

  Autonomic & autacoid pharmacology 20051001

• Contribution of cytochrome P450 metabolites of arachidonic acid to hypertension and end-organ damage in spontaneously hypertensive rats treated with L-NAME.

  Autonomic & autacoid pharmacology 20051001

• Matrix metalloproteinases of epithelial origin in facial sebum of patients with acne and their regulation by isotretinoin.

  The Journal of investigative dermatology 20051001

• Attenuation of breast tumor cell growth by conjugated linoleic acid via inhibition of 5-lipoxygenase activating protein.

  Biochimica et biophysica acta 20051001

• N-3 fatty acid deficiency induced by a modified artificial rearing method leads to poorer performance in spatial learning tasks.

  Pediatric research 20051001

• Distribution, depletion and recovery of docosahexaenoic acid are region-specific in rat brain.

  The British journal of nutrition 20051001

• Arachidonic Acid-Induced COX-1 and COX-2-Mediated Vasodilation in Rat Gingival Arterioles In Vivo.

  The Japanese journal of physiology 20051001

• Structure-activity relationship studies of 3-dodecanoylindole-2-carboxylic acid inhibitors of cytosolic phospholipase A2alpha-mediated arachidonic acid release in intact platelets: variation of the keto moiety.

  Journal of enzyme inhibition and medicinal chemistry 20051001

• Paradoxical effect of n-3-containing vegetable oils on long-chain n-3 fatty acids in rat heart.

  Lipids 20051001

• Modulation of respiratory syncytial virus-induced prostaglandin E2 production by n-3 long-chain polyunsaturated fatty acids in human respiratory epithelium.

  Lipids 20051001

• The effect of supplementation of docosahexaenoic acid and arachidonic acid on visual acuity and neurodevelopment in larger preterm infants.

  Chang Gung medical journal 20051001

• Novel mechanisms of nonsteroidal anti-inflammatory drug-induced renal toxicity.

  Expert opinion on drug metabolism & toxicology 20051001

• Low dose aspirin depresses human platelet aggregation triggered by activating agents whose mechanisms involve arachidonic acid.

  Journal of the College of Physicians and Surgeons--Pakistan : JCPSP 20051001

• Involvement of cannabinoid CB(2) receptor-mediated response and efficacy of cannabinoid CB(2) receptor inverse agonist, JTE-907, in cutaneous inflammation in mice.

  European journal of pharmacology 20050927

• G204D, a mutation that blocks the proton-conducting D-channel of the aa3-type cytochrome c oxidase from Rhodobacter sphaeroides.

  Biochemistry 20050927

• The anti-apoptotic effects of nordihydroguaiaretic acid: inhibition of cPLA(2) activation during TNF-induced apoptosis arises from inhibition of calcium signaling.

  Life sciences 20050923

• Uteroglobin inhibits prostaglandin F2alpha receptor-mediated expression of genes critical for the production of pro-inflammatory lipid mediators.

  The Journal of biological chemistry 20050923

• Cytochrome P450/NADPH-dependent biosynthesis of 5,6-trans-epoxyeicosatrienoic acid from 5,6-trans-arachidonic acid.

  The Biochemical journal 20050915

• Tumor necrosis factor-alpha as trigger of platelet activation in patients with heart failure.

  Blood 20050915

• Arachidonate-regulated Ca2+-selective (ARC) channel activity is modulated by phosphorylation and involves an A-kinase anchoring protein.

  The Journal of physiology 20050915

• Inhibitors of actin polymerisation stimulate arachidonic acid release and 5-lipoxygenase activation by upregulation of Ca2+ mobilisation in polymorphonuclear leukocytes involving Src family kinases.

  Biochimica et biophysica acta 20050915

• The effect of supplementation with n-6 polyunsaturated fatty acids on 1-, 2- and 3-series prostaglandin F production by ovine uterine epithelial cells.

  Biochimica et biophysica acta 20050915

• Conversion of acetaminophen to the bioactive N-acylphenolamine AM404 via fatty acid amide hydrolase-dependent arachidonic acid conjugation in the nervous system.

  The Journal of biological chemistry 20050909

• 15S-Lipoxygenase-2 mediates arachidonic acid-stimulated adhesion of human breast carcinoma cells through the activation of TAK1, MKK6, and p38 MAPK.

  The Journal of biological chemistry 20050909

• n-3 polyunsaturated fatty acids supplementation decreases asymmetric dimethyl arginine and arachidonate accumulation in aging spontaneously hypertensive rats.

  European journal of nutrition 20050901

• Docosahexaenoic acid induces apoptosis in proliferating human endothelial cells.

  Journal of cellular physiology 20050901

• Blood mononuclear cells and platelets have abnormal fatty acid composition in homozygous sickle cell disease.

  Annals of hematology 20050901

• Arachidonic acid metabolites, hydrogen peroxide, and EDHF in cerebral arteries.

  American journal of physiology. Heart and circulatory physiology 20050901

• Arachidonic acid, an omega-6 fatty acid, induces cytoplasmic phospholipase A2 in prostate carcinoma cells.

  Carcinogenesis 20050901

• Simultaneous quantitative determination of deuterium- and carbon-13-labeled essential fatty acids in rat plasma.

  Journal of lipid research 20050901

• In vivo conversion of 18- and 20-C essential fatty acids in rats using the multiple simultaneous stable isotope method.

  Journal of lipid research 20050901

• The last five amino acid residues at the C-terminus of PRK1/PKN is essential for full lipid responsiveness.

  Cellular signalling 20050901

• Role of Ca2+-independent phospholipase A2 and cytochrome P-450 in store-operated calcium entry in 3T6 fibroblasts.

  Biochemical pharmacology 20050901

• Acyl-coenzyme A:cholesterol acyltransferase promotes oxidized LDL/oxysterol-induced apoptosis in macrophages.

  Journal of lipid research 20050901

• Lipids and two-pore domain K+ channels in excitable cells.

  Prostaglandins & other lipid mediators 20050901

• Lipid mediators regulating pain sensitivity.

  Prostaglandins & other lipid mediators 20050901

• In vivo approaches and rationale for quantifying kinetics and imaging brain lipid metabolic pathways.

  Prostaglandins & other lipid mediators 20050901

• Uroguanylin and guanylin regulate transport of mouse cortical collecting duct independent of guanylate cyclase C.

  Kidney international 20050901

• Effects of 4-piperidinomethyl-2-isopropyl-5-methylphenol on oxidative stress and calcium current.

  The Journal of pharmacy and pharmacology 20050901

• Variables influencing Platelet Function Analyzer-100 closure times in healthy individuals.

  British journal of haematology 20050901

• Despite transient ketosis, the classic high-fat ketogenic diet induces marked changes in fatty acid metabolism in rats.

  Metabolism: clinical and experimental 20050901

• An antithrombotic agent, NQ301, inhibits thromboxane A2 receptor and synthase activity in rabbit platelets.

  Basic & clinical pharmacology & toxicology 20050901

• Diabetic embryopathy: studies using a rat embryo culture system and an animal model.

  Congenital anomalies 20050901

• Effects of SKI306X on arachidonate metabolism and other inflammatory mediators.

  Biological & pharmaceutical bulletin 20050901

• Cytochrome P450 4A isoform inhibitory profile of N-hydroxy-N'-(4-butyl-2-methylphenyl)-formamidine (HET0016), a selective inhibitor of 20-HETE synthesis.

  Biological & pharmaceutical bulletin 20050901

• Calcium sensitization as a pharmacological target in vascular smooth-muscle regulation.

  Current opinion in investigational drugs (London, England : 2000) 20050901

• [Isolation and functional identification of delta 5 desaturase gene from Mortierella alpina].

  Yi chuan xue bao = Acta genetica Sinica 20050901

• Abnormal eicosanoid-pattern of peripheral white-blood cells in gastro-intestinal cancer.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20050901

• Effect of prednisolone on secondary messenger metabolism in the lymphocytes from patients with acantholysis bullosa.

  Bulletin of experimental biology and medicine 20050901

• Techniques for delivery of arachidonic acid to Pacific oyster, Crassostrea gigas, spat.

  Lipids 20050901

• GABA, progesterone and zona pellucida activation of PLA2 and regulation by MEK-ERK1/2 during acrosomal exocytosis in guinea pig spermatozoa.

  FEBS letters 20050829

• Arachidonic acid and long-chain n-3 polyunsaturated fatty acid contents in meat of selected poultry and fish species in relation to dietary fat sources.

  Journal of agricultural and food chemistry 20050824

• Lipids as bioeffectors in the immune system.

  Life sciences 20050819

• Elevation of intracellular Ca2+ modulates A-currents in rat cerebellar granule neurons.

  Journal of neuroscience research 20050815

• Spectroscopic characterization of the EF-hand domain of phospholipase C delta1: identification of a lipid interacting domain.

  Archives of biochemistry and biophysics 20050815

• Nitric oxide stimulated vascular smooth muscle cells undergo apoptosis induced in part by arachidonic acid derived eicosanoids.

  Journal of cellular physiology 20050801

• Specific effect of arachidonic acid on inducible nitric oxide synthase mRNA expression in human osteoblastic cells.

  Clinical science (London, England : 1979) 20050801

• Involvement of extracellular Ca2+ influx through voltage-independent Ca2+ channels in endothelin-1 function.

  Cellular signalling 20050801

• Type 2 diabetic mice have increased arteriolar tone and blood pressure: enhanced release of COX-2-derived constrictor prostaglandins.

  Arteriosclerosis, thrombosis, and vascular biology 20050801

• Differential effects of eicosapentaenoic and docosahexaenoic acids upon oxidant-stimulated release and uptake of arachidonic acid in human lymphoma U937 cells.

  Pharmacological research 20050801

• Characterization of four different effects elicited by H2O2 in rat aorta.

  Vascular pharmacology 20050801

• Assessment of the antiplatelet effects of low to medium dose aspirin in the early and late phases after ischaemic stroke and TIA.

  Platelets 20050801

• A new point-of-care method for monitoring anti-platelet therapy: application of the cone and plate(let) analyzer.

  Platelets 20050801

• Effect of arachidonic, eicosapentaenoic and docosahexaenoic acids on the oxidative status of C6 glioma cells.

  Free radical research 20050801

• Altered NF-kappaB gene expression and collagen formation induced by polyunsaturated fatty acids.

  The Journal of nutritional biochemistry 20050801

• Long-chain polyunsaturated fatty acids modulate lung inflammatory response induced by Pseudomonas aeruginosa in mice.

  Pediatric research 20050801

• Blood profiles, body fat and mood state in healthy subjects on different diets supplemented with Omega-3 polyunsaturated fatty acids.

  European journal of clinical investigation 20050801

• Five new triterpene glycosides from Lysimachia foenum-graecum and evaluation of their effect on the arachidonic acid metabolizing enzyme.

  Planta medica 20050801

• Anti-platelet aggregating and anti-oxidative activities of 11-O-(4'-O-methylgalloyl)-bergenin, a new compound isolated from Crassula cv. 'Himaturi'.

  Planta medica 20050801

• D2 but not D1 dopamine receptor stimulation augments brain signaling involving arachidonic acid in unanesthetized rats.

  Psychopharmacology 20050801

• [The effect of compound macrostem onion capsule on metabolism of arachidonic acid in a rat model of monocrotaline-induced pulmonary artery hypertension].

  Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20050801

• Identification and quantification of metabolites of arachidonic acid from cultures of endothelial cells by HPLC-MS2.

  Xenobiotica; the fate of foreign compounds in biological systems 20050801

• Pseudo-phosphorylation of tau at Ser202 and Thr205 affects tau filament formation.

  Brain research. Molecular brain research 20050729

• Protective role for cytosolic phospholipase A2alpha in autoimmune diabetes of mice.

  FEBS letters 20050718

• In vivo characterization of the first acyl-CoA Delta6-desaturase from a member of the plant kingdom, the microalga Ostreococcus tauri.

  The Biochemical journal 20050715

• Regiochemistry of neuroprostanes generated from the peroxidation of docosahexaenoic acid in vitro and in vivo.

  The Journal of biological chemistry 20050715

• ESR spin trapping of a carbon-centered free radical from agonist-stimulated human platelets.

  Free radical biology & medicine 20050715

• Suppression of prostate tumor cell growth by stromal cell prostaglandin D synthase-derived products.

  Cancer research 20050715

• Topiramate does not alter expression in rat brain of enzymes of arachidonic acid metabolism.

  Psychopharmacology 20050701

• Involvement of phospholipase A2 and lipoxygenase in lipopolysaccharide-induced inducible nitric oxide synthase expression in glial cells.

  Glia 20050701

• At least 2 distinct pathways generating reactive oxygen species mediate vascular cell adhesion molecule-1 induction by advanced glycation end products.

  Arteriosclerosis, thrombosis, and vascular biology 20050701

• Cellular distribution, post-translational modification, and tumorigenic potential of human group III secreted phospholipase A(2).

  The Journal of biological chemistry 20050701

• The role of arachidonic acid regulatory enzymes in colorectal disease.

  Diseases of the colon and rectum 20050701

• Heme oxygenase and the cardiovascular-renal system.

  Free radical biology & medicine 20050701

• Arachidonic acid induces neuronal death through lipoxygenase and cytochrome P450 rather than cyclooxygenase.

  Journal of neuroscience research 20050701

• Aging is characterized by a profound reduction in anti-inflammatory lipoxin A4 levels.

  Experimental gerontology 20050701

• 5-Lipoxygenase inhibitors attenuate growth of human renal cell carcinoma and induce apoptosis through arachidonic acid pathway.

  Oncology reports 20050701

• Characterization of inhibition of platelet function by paracetamol and its interaction with diclofenac in vitro.

  Acta anaesthesiologica Scandinavica 20050701

• Effect of docosahexaenoic acid and arachidonic acid on the expression of adipocyte determination and differentiation-dependent factor 1 in differentiating porcine adipocytes.

  Journal of animal science 20050701

• Fetal erythrocyte membrane lipids modification: preliminary observation of an early sign of compromised insulin sensitivity in offspring of gestational diabetic women.

  Diabetic medicine : a journal of the British Diabetic Association 20050701

• The specific thromboxane receptor antagonist S18886: pharmacokinetic and pharmacodynamic studies.

  Journal of thrombosis and haemostasis : JTH 20050701

• Impaired arachidonic acid-mediated activation of large-conductance Ca2+-activated K+ channels in coronary arterial smooth muscle cells in Zucker Diabetic Fatty rats.

  Diabetes 20050701

• COX-2 inhibitors and metabolism of essential fatty acids.

  Medical science monitor : international medical journal of experimental and clinical research 20050701

• Abciximab does not inhibit the increase of thrombin generation produced in platelet-rich plasma in vitro by sodium arachidonate or tissue factor.

  Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20050701

• A Thrombelastograph whole blood assay for clinical monitoring of NSAID-insensitive transcellular platelet activation by arachidonic acid.

  The Journal of laboratory and clinical medicine 20050701

• Characterization of paired helical filaments by scanning transmission electron microscopy.

  Microscopy research and technique 20050701

• New anti-inflammatory formulation containing Synurus deltoides extract.

  Archives of pharmacal research 20050701

• Kinetics of fatty acid oxidation in low density lipoproteins evaluated by registration of the oxidizer consumption and reaction product yield.

  Bulletin of experimental biology and medicine 20050701

• Chemometric discrimination among wild and cultured age-0 largemouth bass, black crappies, and white crappies based on fatty acid composition.

  Journal of agricultural and food chemistry 20050629

• Platelet activation in cystic fibrosis.

  Blood 20050615

• Stereospecific synthesis and mass spectrometry of 5,6-trans-epoxy-8Z,11Z,14Z-eicosatrienoic acid.

  Bioorganic & medicinal chemistry letters 20050615

• Identification and quantification of the hydroxyeicosatetraenoic acids, 20-HETE and 12-HETE, in the cerebrospinal fluid after subarachnoid hemorrhage.

  Journal of neuroscience methods 20050615

• Unsaturated fatty acids induce cytotoxic aggregate formation of amyotrophic lateral sclerosis-linked superoxide dismutase 1 mutants.

  The Journal of biological chemistry 20050603

• Arachidonic acid inhibits capacitative Ca2+ entry and activates non-capacitative Ca2+ entry in cultured astrocytes.

  Biochemical and biophysical research communications 20050603

• Synthesis of all-trans arachidonic acid and its effect on rabbit platelet aggregation.

  Bioorganic & medicinal chemistry letters 20050602

• Phospholipase A2 pathway association with macrophage-mediated polycarbonate-urethane biodegradation.

  Biomaterials 20050601

• Arachidonic acid incorporation and turnover is decreased in sympathetically denervated rat heart.

  American journal of physiology. Heart and circulatory physiology 20050601

• Adipose differentiation-related protein: a gonadotropin- and prostaglandin-regulated protein in primate periovulatory follicles.

  Biology of reproduction 20050601

• Intact actin filaments are required for cytosolic phospholipase A2 translocation but not for its activation by norepinephrine in vascular smooth muscle cells.

  The Journal of pharmacology and experimental therapeutics 20050601

• Increased arachidonic acid concentration in the brain of Flinders Sensitive Line rats, an animal model of depression.

  Journal of lipid research 20050601

• Chronic lithium chloride administration to unanesthetized rats attenuates brain dopamine D2-like receptor-initiated signaling via arachidonic acid.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20050601

• 5-HT2A/2C receptor signaling via phospholipase A2 and arachidonic acid is attenuated in mice lacking the serotonin reuptake transporter.

  Psychopharmacology 20050601

• Steady-state haemoglobin level in sickle cell anaemia increases with an increase in erythrocyte membrane n-3 fatty acids.

  Prostaglandins, leukotrienes, and essential fatty acids 20050601

• Secretory phospholipase A2 enzymes in atherogenesis.

  Current opinion in lipidology 20050601

• The impact of eicosanoids on the crosstalk between innate and adaptive immunity: the key roles of dendritic cells.

  Tissue antigens 20050601

• Contribution of arachidonic acid metabolites derived via cytochrome P4504A to angiotensin II-induced neointimal growth.

  Hypertension (Dallas, Tex. : 1979) 20050601

• A high n-6 polyunsaturated fatty acid diet reduces muscarinic M2/M4 receptor binding in the rat brain.

  Journal of chemical neuroanatomy 20050601

• An arachidonic acid-preferring acyl-CoA synthetase is a hormone-dependent and obligatory protein in the signal transduction pathway of steroidogenic hormones.

  Journal of molecular endocrinology 20050601

• Platelet function disorder in Gardner-Diamond syndrome: a case report and review of the literature.

  Journal of pediatric hematology/oncology 20050601

• Polyunsaturated fatty acid (PUFA) changes in serum and liver of undernourished rats given dietary vitamin B6 supplementation.

  Journal of nutritional science and vitaminology 20050601

• Proangiogenic activity of beta-carotene is coupled with the activation of endothelial cell chemotaxis.

  Biochimica et biophysica acta 20050530

• Fatty acids and expression of adipokines.

  Biochimica et biophysica acta 20050530

• Mitochondrial localization of cyclooxygenase-2 and calcium-independent phospholipase A2 in human cancer cells: implication in apoptosis resistance.

  Experimental cell research 20050515

• Inhibitors of the arachidonic acid pathway and peroxisome proliferator-activated receptor ligands have superadditive effects on lung cancer growth inhibition.

  Cancer research 20050515

• Molecular determinants of cardiac K(ATP) channel activation by epoxyeicosatrienoic acids.

  The Journal of biological chemistry 20050513

• A novel neurotrophic role of secretory phospholipases A2 for cerebellar granule neurons.

  FEBS letters 20050509

• Brain phospholipase C/diacylglycerol lipase are involved in bombesin BB2 receptor-mediated activation of sympatho-adrenomedullary outflow in rats.

  European journal of pharmacology 20050509

• Probing conformational changes of human serum albumin due to unsaturated fatty acid binding by chemical cross-linking and mass spectrometry.

  The Biochemical journal 20050501

• Impaired arachidonic acid-mediated dilation of small mesenteric arteries in Zucker diabetic fatty rats.

  American journal of physiology. Heart and circulatory physiology 20050501

• Angiotensin II-induced Akt activation is mediated by metabolites of arachidonic acid generated by CaMKII-stimulated Ca2(+)-dependent phospholipase A2.

  American journal of physiology. Heart and circulatory physiology 20050501

• A2B adenosine receptor mediates human chorionic vasoconstriction and signals through arachidonic acid cascade.

  American journal of physiology. Heart and circulatory physiology 20050501

• U937 cell necrosis mediated by peroxynitrite is not caused by depletion of ATP and is prevented by arachidonate via an ATP-dependent mechanism.

  Molecular pharmacology 20050501

• Polyunsaturated fatty acids interfere with formation of the immunological synapse.

  Journal of leukocyte biology 20050501

• Body composition in preterm infants who are fed long-chain polyunsaturated fatty acids: a prospective, randomized, controlled trial.

  Pediatric research 20050501

• Qualitative risk assessment of chronic renal failure development in healthy, female cats as based on the content of eicosapentaenoic acid in adipose tissue and that of arachidonic acid in plasma cholesteryl esters.

  Veterinary research communications 20050501

• Agonist activation of arachidonate-regulated Ca2+-selective (ARC) channels in murine parotid and pancreatic acinar cells.

  The Journal of physiology 20050501

• Eicosanoids influence in vitro elongation of plasmatocytes from the tobacco hornworm, Manduca sexta.

  Archives of insect biochemistry and physiology 20050501

• Eicosanoids mediate the laminarin-induced nodulation response in larvae of the flesh fly, Neobellieria bullata.

  Archives of insect biochemistry and physiology 20050501

• Functional diversity of AT2 receptor orthologues in closely related species.

  Kidney international 20050501

• N-6 polyunsaturated fatty acids confer hemodynamic stability in an experimental model of multiple trauma.

  Prostaglandins, leukotrienes, and essential fatty acids 20050501

• 15-lipoxygenase metabolites of gamma-linolenic acid/eicosapentaenoic acid suppress growth and arachidonic acid metabolism in human prostatic adenocarcinoma cells: possible implications of dietary fatty acids.

  Prostaglandins, leukotrienes, and essential fatty acids 20050501

• Dual inhibition of cyclo-oxygenases and 5-lipoxygenase: a novel therapeutic approach to inflammation?

  Joint, bone, spine : revue du rhumatisme 20050501

• Fatty acid oxidation in the pathogenesis of Alzheimer's disease.

  The American journal of pathology 20050501

• Expression of PPARgamma and beta/delta in human primary osteoblastic cells: influence of polyunsaturated fatty acids.

  Calcified tissue international 20050501

• Dual role of oxygen during lipoxygenase reactions.

  The FEBS journal 20050501

• Arachidonic acid cascade in endothelial pathobiology.

  Microvascular research 20050501

• Fatty acids add grease to exocytosis.

  Chemistry & biology 20050501

• Arachidonic acid allows SNARE complex formation in the presence of Munc18.

  Chemistry & biology 20050501

• Possible anti-inflammatory role of COX-2-derived prostaglandins: implications for inflammation research.

  Current opinion in investigational drugs (London, England : 2000) 20050501

• Hydroperoxide characterisation as a signature of the micelle/monomer balance in radiation-induced peroxidation of arachidonate.

  Free radical research 20050501

• High-level production of arachidonic acid by fed-batch culture of Mortierella alpina using NH4OH as a nitrogen source and pH control.

  Biotechnology letters 20050501

• Topiramate does not alter the kinetics of arachidonic or docosahexaenoic acid in brain phospholipids of the unanesthetized rat.

  Neurochemical research 20050501

• Redirection of eicosanoid metabolism in mPGES-1-deficient macrophages.

  The Journal of biological chemistry 20050429

• Role of regulatory F-domain in hepatocyte nuclear factor-4alpha ligand specificity.

  The Journal of biological chemistry 20050429

• Brain arachidonic acid incorporation is decreased in heart fatty acid binding protein gene-ablated mice.

  Biochemistry 20050426

• H2O2 activates Nox4 through PLA2-dependent arachidonic acid production in adult cardiac fibroblasts.

  FEBS letters 20050425

• ERK1/2-dependent regulation of U937 cell survival after exposure to peroxynitrite.

  Biochemical and biophysical research communications 20050422

• Upregulation of angiotensin II type 1 receptor, inflammatory mediators, and enzymes of arachidonate metabolism in obese Zucker rat kidney: reversal by angiotensin II type 1 receptor blockade.

  Circulation 20050419

• A downstream role for protein kinase Calpha in the cytosolic phospholipase A2-dependent protective signalling mediated by peroxynitrite in U937 cells.

  Biochemical pharmacology 20050415

• Major artifacts encountered in studying biological samples containing ferric protoporphyrin IX.

  Analytical biochemistry 20050415

• Hepatic arachidonic acid metabolism is disrupted after hexachlorobenzene treatment.

  Toxicology and applied pharmacology 20050415

• Compliance as a critical consideration in patients who appear to be resistant to aspirin after healing of myocardial infarction.

  The American journal of cardiology 20050415

• Prostaglandin D(2) and J(2) induce apoptosis in human leukemia cells via activation of the caspase 3 cascade and production of reactive oxygen species.

  Biochimica et biophysica acta 20050415

• MAPKs mediate the activation of cytosolic phospholipase A2 by amyloid beta(25-35) peptide in bovine retina pericytes.

  Biochimica et biophysica acta 20050415

• Polyunsaturated fatty acids block dendritic cell activation and function independently of NF-kappaB activation.

  The Journal of biological chemistry 20050408

• Group VIB Ca2+-independent phospholipase A2gamma promotes cellular membrane hydrolysis and prostaglandin production in a manner distinct from other intracellular phospholipases A2.

  The Journal of biological chemistry 20050408

• Proteolytic activation of protein kinase Calpha by peroxynitrite in stimulating cytosolic phospholipase A2 in pulmonary endothelium: involvement of a pertussis toxin sensitive protein.

  Biochemistry 20050405

• Effect of EGF on H2O2-induced inhibition of alpha-MG uptake in renal proximal tubule cells: involvement of MAPK and AA release.

  Journal of cellular physiology 20050401

• Expression of secretory phospholipase A2 enzymes in lungs of humans with pneumonia and their potential prostaglandin-synthetic function in human lung-derived cells.

  The Biochemical journal 20050401

• Inflammation induced changes in arachidonic acid metabolism in cat LES circular muscle.

  American journal of physiology. Gastrointestinal and liver physiology 20050401

• Protease-activated receptor stimulation activates a Ca2+-independent phospholipase A2 in bladder microvascular endothelial cells.

  American journal of physiology. Renal physiology 20050401

• Differential effects of IL-10 on prostaglandin H synthase-2 expression and prostaglandin E2 biosynthesis between spleen and bone marrow macrophages.

  Journal of leukocyte biology 20050401

• Decreased n-6/n-3 fatty acid ratio reduces the invasive potential of human lung cancer cells by downregulation of cell adhesion/invasion-related genes.

  Carcinogenesis 20050401

• An integrative metabolism approach identifies stearoyl-CoA desaturase as a target for an arachidonate-enriched diet.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050401

• Effects of 2,2',4,4'-tetrachlorobiphenyl on granulocytic HL-60 cell function and expression of cyclooxygenase-2.

  Toxicological sciences : an official journal of the Society of Toxicology 20050401

• Inhibition of COX activity by NSAIDs or ascorbate increases cAMP levels and enhances differentiation in 1alpha,25-dihydroxyvitamin D3-induced HL-60 cells.

  Archives of biochemistry and biophysics 20050401

• Differential impact of prostaglandin H synthase 1 knockdown on platelets and parturition.

  The Journal of clinical investigation 20050401

• Leukotriene and prostaglandin synthesis pathways in osteoarthritic synovial membranes: regulating factors for interleukin 1beta synthesis.

  The Journal of rheumatology 20050401

• Avena Rhealba inhibits A23187-stimulated arachidonic acid mobilization, eicosanoid release, and cPLA2 expression in human keratinocytes: potential in cutaneous inflammatory disorders.

  Biological & pharmaceutical bulletin 20050401

• Cell specific effects of polyunsaturated fatty acids on 5-aminolevulinic acid based photosensitization.

  Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20050401

• Growth and development of preterm infants fed infant formulas containing docosahexaenoic acid and arachidonic acid.

  The Journal of pediatrics 20050401

• Correlation between in vitro aggregation and thromboxane A2 production in fresh, liquid-preserved, and cryopreserved human platelets: effect of agonists, pH, and plasma and saline resuspension.

  Transfusion 20050401

• Gender differences of renal CYP-derived eicosanoid synthesis in rats fed a high-fat diet.

  American journal of hypertension 20050401

• Arachidonic acid signaling in pathogenesis of allergy: therapeutic implications.

  Current drug targets. Inflammation and allergy 20050401

• Correlation between dietary polyunsaturated fatty acids and plasma homocysteine concentration in vitamin B6-deficient rats.

  Nutrition, metabolism, and cardiovascular diseases : NMCD 20050401

• Activity of taraxasteryl acetate on inflammation and heat shock protein synthesis.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20050401

• Association of fatty acids in serum phospholipids with hay fever, specific and total immunoglobulin E.

  The British journal of nutrition 20050401

• [Development of adipose tissue and dietary lipids: from basic science to medicine].

  Annales d'endocrinologie 20050401

• Arachidonic acid improves aged rats' spatial cognition.

  Physiology & behavior 20050331

• Interference of arachidonic acid and its metabolites with TNF-alpha release by ochratoxin A from rat liver.

  Toxicology 20050330

• Slow proton transfer through the pathways for pumped protons in cytochrome c oxidase induces suicide inactivation of the enzyme.

  Biochemistry 20050329

• Long-chain acyl-CoA synthetase 6 preferentially promotes DHA metabolism.

  The Journal of biological chemistry 20050318

• The N-terminal membrane anchor domain of the membrane-bound prostacyclin synthase involved in the substrate presentation of the coupling reaction with cyclooxygenase.

  Archives of biochemistry and biophysics 20050315

• Novel role of lipoxygenases in the inflammatory response: promotion of TNF mRNA decay by 15-hydroperoxyeicosatetraenoic acid in a monocytic cell line.

  Journal of immunology (Baltimore, Md. : 1950) 20050315

• Cytoplasmic phospholipase A2 levels correlate with apoptosis in human colon tumorigenesis.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20050315

• Cytosolic phospholipase A2-alpha is necessary for platelet-activating factor biosynthesis, efficient neutrophil-mediated bacterial killing, and the innate immune response to pulmonary infection: cPLA2-alpha does not regulate neutrophil NADPH oxidase activity.

  The Journal of biological chemistry 20050304

• Protein kinase C signaling as a survival pathway against CYP2E1-derived oxidative stress and toxicity in HepG2 cells.

  The Journal of pharmacology and experimental therapeutics 20050301

• Cyclooxygenase-2 and an early stage of chronic hypoxia-induced pulmonary hypertension in newborn pigs.

  Journal of applied physiology (Bethesda, Md. : 1985) 20050301

• Angiotensin II-induced Akt activation through the epidermal growth factor receptor in vascular smooth muscle cells is mediated by phospholipid metabolites derived by activation of phospholipase D.

  The Journal of pharmacology and experimental therapeutics 20050301

• Endothelium-derived 2-arachidonylglycerol: an intermediate in vasodilatory eicosanoid release in bovine coronary arteries.

  American journal of physiology. Heart and circulatory physiology 20050301

• Chronic lithium administration to rats selectively modifies 5-HT2A/2C receptor-mediated brain signaling via arachidonic acid.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20050301

• Interactions between nitric oxide and arachidonic acid in lung epithelial cells: possible roles for peroxynitrite and superoxide.

  Pharmacology 20050301

• Defect in regulation of Ca2+ movement in platelets from patients with systemic lupus erythematosus.

  Pharmacology 20050301

• Dexamethasone up-regulates the inhibitory adaptor protein Dok-1 and suppresses downstream activation of the mitogen-activated protein kinase pathway in antigen-stimulated RBL-2H3 mast cells.

  Molecular pharmacology 20050301

• The arachidonic acid-binding protein S100A8/A9 promotes NADPH oxidase activation by interaction with p67phox and Rac-2.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050301

• Ischemic preconditioning increases antioxidants in the brain and peripheral organs after cerebral ischemia.

  Experimental neurology 20050301

• Effect of dietary docosahexaenoic acid on the endothelium-dependent vasorelaxation in diabetic rats.

  Clinical and experimental pharmacology & physiology 20050301

• Overexpression of 5-lipoxygenase and cyclooxygenase 2 in hamster and human oral cancer and chemopreventive effects of zileuton and celecoxib.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20050301

• Pulmonary and systemic hemodynamic responses to intravenous prostacyclin in broilers.

  Poultry science 20050301

• Lipid peroxidation of a human hepatoma cell line (HepG2) after incorporation of linoleic acid, arachidonic acid, and docosahexaenoic acid.

  Bioscience, biotechnology, and biochemistry 20050301

• The chemical composition of the uropygial gland secretion of rock dove Columba livia.

  Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20050301

• Mechanisms of ATP action on motor nerve terminals at the frog neuromuscular junction.

  The European journal of neuroscience 20050301

• Augmentation of allergic inflammation in the airways of cyclooxygenase-2-deficient mice.

  Respirology (Carlton, Vic.) 20050301

• [Nutritional factors and functional assessment].

  Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 20050301

• [Presynaptic effects of arachidonic acid and prostaglandin E2 in the frog neuromuscular synapse].

  Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20050301

• Group VIA phospholipase A2 forms a signaling complex with the calcium/calmodulin-dependent protein kinase IIbeta expressed in pancreatic islet beta-cells.

  The Journal of biological chemistry 20050225

• Enhanced expressions of arachidonic acid-sensitive tandem-pore domain potassium channels in rat experimental acute cerebral ischemia.

  Biochemical and biophysical research communications 20050225

• Synthesis and biological activity of the tea catechin metabolites, M4 and M6 and their methoxy-derivatives.

  Bioorganic & medicinal chemistry letters 20050215

• Green tea constituent epigallocatechin-3-gallate selectively inhibits COX-2 without affecting COX-1 expression in human prostate carcinoma cells.

  International journal of cancer 20050210

• Packing and viscoelasticity of polyunsaturated omega-3 and omega-6 lipid bilayers as seen by (2)H NMR and X-ray diffraction.

  Journal of the American Chemical Society 20050209

• Effects of unsaturated fatty acids on calcium-activated potassium current in gastric myocytes of guinea pigs.

  World journal of gastroenterology 20050207

• Interaction of polyunsaturated fatty acids and sodium butyrate during apoptosis in HT-29 human colon adenocarcinoma cells.

  European journal of nutrition 20050201

• Sulodexide attenuates myocardial ischemia/reperfusion injury and the deposition of C-reactive protein in areas of infarction without affecting hemostasis.

  The Journal of pharmacology and experimental therapeutics 20050201

• The cardiac beta2-adrenergic signalling a new role for the cPLA2.

  Cellular signalling 20050201

• The E5 protein of the human papillomavirus type 16 modulates composition and dynamics of membrane lipids in keratinocytes.

  Archives of virology 20050201

• Colorectal adenoma risk is modified by the interplay between polymorphisms in arachidonic acid pathway genes and fish consumption.

  Carcinogenesis 20050201

• Long-chain conversion of [13C]linoleic acid and alpha-linolenic acid in response to marked changes in their dietary intake in men.

  Journal of lipid research 20050201

• Quantification of isoprostanes as indices of oxidant stress and the risk of atherosclerosis in humans.

  Arteriosclerosis, thrombosis, and vascular biology 20050201

• Characterization of the insulinotropic action of a phospholipase A2 isolated from Crotalus durissus collilineatus rattlesnake venom on rat pancreatic islets.

  Toxicon : official journal of the International Society on Toxinology 20050201

• The Janus face of cyclooxygenase-2 in ischemic stroke: shifting toward downstream targets.

  Stroke 20050201

• Calcium-independent phospholipase A2 is regulated by a novel protein kinase C in human coronary artery endothelial cells.

  American journal of physiology. Cell physiology 20050201

• Fatty acid intake and incident nephrolithiasis.

  American journal of kidney diseases : the official journal of the National Kidney Foundation 20050201

• Effects of alcohol intake during pregnancy on docosahexaenoic acid and arachidonic acid in umbilical cord vessels of black women.

  Pediatrics 20050201

• Ternary complexes of gentamicin with iron and lipid catalyze formation of reactive oxygen species.

  Chemical research in toxicology 20050201

• Oxidative stress in the molecular mechanism of pathogenesis at different diseased states of organism in clinics and experiment.

  Current drug targets. Inflammation and allergy 20050201

• Synthesis of baicalein derivatives as potential anti-aggregatory and anti-inflammatory agents.

  The Journal of pharmacy and pharmacology 20050201

• Pathophysiological role of 20-HETE a cytochrome P450 metabolite of arachidonic acid.

  Journal of pharmacological sciences 20050201

• In vivo effects of isatin on rat platelet eicosanoids.

  Platelets 20050201

• Platelet aggregation testing in platelet-rich plasma: description of procedures with the aim to develop standards in the field.

  American journal of clinical pathology 20050201

• Lipid lowering drugs and polyunsaturated fatty acids.

  Nutrition, metabolism, and cardiovascular diseases : NMCD 20050201

• Syntheses and anti-inflammatory activity of diphenylamine-2,2'-dicarboxylic acid and its metal complexes.

  Journal of enzyme inhibition and medicinal chemistry 20050201

• Application of QSAR analysis to organic anion transporting polypeptide 1a5 (Oatp1a5) substrates.

  Bioorganic & medicinal chemistry 20050117

• Arachidonic acid inhibits the store-operated Ca2+ current in rat liver cells.

  The Biochemical journal 20050115

• Vascular protective effects of cytochrome p450 epoxygenase-derived eicosanoids.

  Archives of biochemistry and biophysics 20050115

• Molecular basis for TPR domain-mediated regulation of protein phosphatase 5.

  The EMBO journal 20050112

• Specific formation of arachidonic acid and eicosapentaenoic acid by a front-end Delta5-desaturase from Phytophthora megasperma.

  Biochimica et biophysica acta 20050105

• Functional variant of CYP4A11 20-hydroxyeicosatetraenoic acid synthase is associated with essential hypertension.

  Circulation 20050104

• Cytochrome P-450 under pressure: more evidence for a link between 20-hydroxyeicosatetraenoic acid and hypertension.

  Circulation 20050104

• Tumor necrosis factor-alpha stimulates gastric epithelial cell proliferation.

  American journal of physiology. Gastrointestinal and liver physiology 20050101

• Antiplatelet activity of J78 (2-Chloro-3-[2'-bromo, 4'-fluoro-phenyl]-amino-8-hydroxy-1,4-naphthoquinone), an antithrombotic agent, is mediated by thromboxane (TX) A2 receptor blockade with TXA2 synthase inhibition and suppression of cytosolic Ca2+ mobilization.

  The Journal of pharmacology and experimental therapeutics 20050101

• Decreased epoxygenase and increased epoxide hydrolase expression in the mesenteric artery of obese Zucker rats.

  American journal of physiology. Regulatory, integrative and comparative physiology 20050101

• Human protein phosphatase 5 dissociates from heat-shock proteins and is proteolytically activated in response to arachidonic acid and the microtubule-depolymerizing drug nocodazole.

  The Biochemical journal 20050101

• Cyclooxygenase- and lipoxygenase-dependent relaxation to arachidonic acid in rabbit small mesenteric arteries.

  American journal of physiology. Heart and circulatory physiology 20050101

• The effects of hypoxia on the modulation of human TREK-1 potassium channels.

  The Journal of physiology 20050101

• Cytosolic phospholipase A2 mediates neuronal apoptosis induced by soluble oligomers of the amyloid-beta peptide.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050101

• Resistin expression in 3T3-L1 adipocytes is reduced by arachidonic acid.

  Journal of lipid research 20050101

• The lipid-activated two-pore domain K+ channel TREK-1 is resistant to hypoxia: implication for ischaemic neuroprotection.

  The Journal of physiology 20050101

• Developmental control of cAMP-induced Ca2+-influx by cGMP: influx is delayed and reduced in a cGMP-phosphodiesterase D deficient mutant of Dictyostelium discoideum.

  Cell calcium 20050101

• Association of plasma apolipoproteins D with RBC membrane arachidonic acid levels in schizophrenia.

  Schizophrenia research 20050101

• Decreased levels of cytochrome P450 2E1-derived eicosanoids sensitize renal arteries to constrictor agonists in spontaneously hypertensive rats.

  Hypertension (Dallas, Tex. : 1979) 20050101

• Lower fetal status of docosahexaenoic acid, arachidonic acid and essential fatty acids is associated with less favorable neonatal neurological condition.

  Prostaglandins, leukotrienes, and essential fatty acids 20050101

• Fatty acid profile of human saliva: a possible indicator of dietary fat intake.

  Archives of oral biology 20050101

• Inducible NOS inhibition, eicosapentaenoic acid supplementation, and angiotensin II-induced renal damage.

  Kidney international 20050101

• The selective cyclooxygenase-2 inhibitor celecoxib modulates the formation of vasoconstrictor eicosanoids and activates PPARgamma. Influence of albumin.

  Journal of hepatology 20050101

• AMPA receptor phosphorylation is selectively regulated by constitutive phospholipase A(2) and 5-lipoxygenase activities.

  Hippocampus 20050101

• Clinical efficacy of n-3 fatty acid supplementation in patients with asthma.

  Journal of the American Dietetic Association 20050101

• Introduction for special forum issue on isoprostanes and related compounds.

  Antioxidants & redox signaling 20050101

• Free radical oxidation of plasmalogen glycerophosphocholine containing esterified docosahexaenoic acid: structure determination by mass spectrometry.

  Antioxidants & redox signaling 20050101

• The cyclopentenone (A2/J2) isoprostanes--unique, highly reactive products of arachidonate peroxidation.

  Antioxidants & redox signaling 20050101

• Factors regulating isoprostane formation in vivo.

  Antioxidants & redox signaling 20050101

• Antiplatelet activity of BRX-018, (6aS,cis)-malonic acid 3-acetoxy-6a9-bis-(2-methoxycarbonyl-acetoxy)-6,6a,7,11b-tetrahydro-indeno[2,1-c]chromen-10-yl ester methylester.

  Thrombosis research 20050101

• Differential utilization of hepatic and myocardial fatty acids during forced molt of laying hens.

  Poultry science 20050101

• Cholesterol and n-3 and n-6 fatty acid content in eggs from laying hens fed with red crab meal (Pleuroncodes planipes).

  Poultry science 20050101

• Enhanced antiplatelet effects of clopidogrel plus acetylsalicylic acid compared with acetylsalicylic acid alone or combined with extended-release dipyridamole in healthy volunteers.

  Cerebrovascular diseases (Basel, Switzerland) 20050101

• The comparison of Ca2+/CaM-independent and Ca2+/CaM-dependent phosphorylation of myosin light chains by MLCK.

  Physiological research 20050101

• Effect of supplementation with docosahexaenoic acid ethyl ester and sn-2 docosahexaenyl monoacylglyceride on plasma and erythrocyte fatty acids in rats.

  Annals of nutrition & metabolism 20050101

• Dual effect of isoprostanes on the release of [3H]D-aspartate from isolated bovine retinae: role of arachidonic acid metabolites.

  Neurochemical research 20050101

• Group X secretory phospholipase A2 can induce arachidonic acid release and eicosanoid production without activation of cytosolic phospholipase A2 alpha.

  Prostaglandins & other lipid mediators 20050101

• 5-lipoxygenase expression and activity in aorta from streptozotocin-induced diabetic rats.

  Prostaglandins & other lipid mediators 20050101

• Direct coupling between arachidonic acid-induced Ca2+ release and Ca2+ entry in HEK293 cells.

  Prostaglandins & other lipid mediators 20050101

• Molecular evidence that the rate-limiting step for the biosynthesis of arachidonic acid in Mortierella alpina is at the level of an elongase.

  Lipids 20050101

• Apoptosis induced by membrane damage in human lymphocytes; effects of arachidonic acid and its photoproducts.

  Acta biochimica Polonica 20050101

• The role of alterations in arachidonic acid metabolism and nitric oxide homeostasis in rat models of diabetes during early pregnancy.

  Current pharmaceutical design 20050101

• The role of COX-2 in acute pain and the use of selective COX-2 inhibitors for acute pain relief.

  Current pharmaceutical design 20050101

• The effects of non-steroidal anti-inflammatory drugs (selective and non-selective) on the treatment of periodontal diseases.

  Current pharmaceutical design 20050101

• beta-Carotene stimulates chemotaxis of human endothelial progenitor cells.

  Clinical chemistry and laboratory medicine 20050101

• Inhibiting long-chain fatty acyl CoA synthetase does not increase agonist-induced release of arachidonate metabolites from human endothelial cells.

  Journal of vascular research 20050101

• Cyclooxygenase, a key enzyme family for production of prostaglandins, is present in human mast cell lipid bodies.

  Chemical immunology and allergy 20050101

• The influence of long chain polyunsaturate supplementation on docosahexaenoic acid and arachidonic acid in baboon neonate central nervous system.

  BMC medicine 20050101

• Tetrandrine and thapsigargin release arachidonic acid from cells in culture and stimulate prostacyclin production in rat liver cells, but may do so by different pathways.

  BMC pharmacology 20050101

• Lipoxin signaling in neutrophils and their role in periodontal disease.

  Prostaglandins, leukotrienes, and essential fatty acids 20050101

• The role of essential fatty acids in development.

  Annual review of nutrition 20050101

• Inducible nitric oxide synthase links NF-kappaB to PGE2 in polyunsaturated fatty acid altered fibroblast in-vitro wound healing.

  Lipids in health and disease 20050101

• Influence of vitamin E on the antiplatelet effect of acetylsalicylic acid in human blood.

  Platelets 20050101

• Tissue accretion and milk content of docosahexaenoic acid in female rats after supplementation with different docosahexaenoic acid sources.

  Annals of nutrition & metabolism 20050101

• Kinetics of radical-scavenging activity of hesperetin and hesperidin and their inhibitory activity on COX-2 expression.

  Anticancer research 20050101

• Host response modulation in the management of periodontal diseases.

  Journal of clinical periodontology 20050101

• Cytochrome P450 products and arachidonic acid-induced, non-store-operated, Ca2+ entry in cultured bovine endothelial cells.

  Endothelium : journal of endothelial cell research 20050101

• Modulation of lymphocyte proliferation by macrophages and macrophages loaded with arachidonic acid.

  Cell biochemistry and function 20050101

• Calcium-dependent and independent mechanisms of capsaicin receptor (TRPV1)-mediated cytokine production and cell death in human bronchial epithelial cells.

  Journal of biochemical and molecular toxicology 20050101

• Inhibition of ligand binding to G protein-coupled receptors by arachidonic acid.

  Journal of molecular neuroscience : MN 20050101

• Maternal fish oil supplementation in lactation: effect on developmental outcome in breast-fed infants.

  Reproduction, nutrition, development 20050101

• Effect of randomized supplementation with high dose olive, flax or fish oil on serum phospholipid fatty acid levels in adults with attention deficit hyperactivity disorder.

  Reproduction, nutrition, development 20050101

• Regulation of intracellular calcium levels by polyunsaturated fatty acids, arachidonic acid and docosahexaenoic acid, in astrocytes: possible involvement of phospholipase A2.

  Reproduction, nutrition, development 20050101

• Mechanisms for the prevention of gastrointestinal cancer: the role of prostaglandin E2.

  Oncology 20050101

• COX-2 and prostaglandins in atherosclerosis.

  Lupus 20050101

• Plant-based diet, serum fatty acid profile, and free radicals in postmenopausal women: the diet and androgens (DIANA) randomized trial.

  The International journal of biological markers 20050101

• The role of antioxidants in models of inflammation: emphasis on L-arginine and arachidonic acid metabolism.

  Inflammopharmacology 20050101

• Serum deprivation and re-addition: effects on cyclooxygenase inhibitor sensitivity in cultured glia.

  Inflammopharmacology 20050101

• Calcium signals activated by arachidonic acid in embryonic chick ciliary ganglion neurons.

  Neuro-Signals 20050101

• Mechanisms and mediators of pulmonary fibrosis.

  Critical reviews in immunology 20050101

• Purinoceptors in renal microvessels: adenosine-activated and cytochrome P450 monooxygenase-derived arachidonate metabolites.

  Pharmacological reports : PR 20050101

• Is conjugated linoleic acid (CLA) a protective factor in atherosclerosis? Study with the use of neural networks.

  Annales Academiae Medicae Stetinensis 20050101

• Potential of radiosensitizing agents in cancer chemo-radiotherapy.

  Journal of cancer research and therapeutics 20050101

• gamma-Tocopherol or combinations of vitamin E forms induce cell death in human prostate cancer cells by interrupting sphingolipid synthesis.

  Proceedings of the National Academy of Sciences of the United States of America 20041221

• Arachidonic acid activates tissue transglutaminase and stress fiber formation via intracellular reactive oxygen species.

  Biochemical and biophysical research communications 20041217

• Binding of arachidonic acid to myeloid-related proteins (S100A8/A9) enhances phagocytic NADPH oxidase activation.

  Biochemical and biophysical research communications 20041217

• Specific polyunsaturated fatty acids drive TRPV-dependent sensory signaling in vivo.

  Cell 20041217

• Inverse association between prostatic polyunsaturated fatty acid and risk of locally advanced prostate carcinoma.

  Cancer 20041215

• (+)-Cannabidiol analogues which bind cannabinoid receptors but exert peripheral activity only.

  European journal of pharmacology 20041215

• Peroxyl radical mediated oxidative DNA base damage: implications for lipid peroxidation induced mutagenesis.

  Biochemistry 20041214

• Compounds stimulating cytosolic phospholipase A2 activity with a combinational action mode.

  Biochemical and biophysical research communications 20041210

• Transfection and functional expression of CYP4A1 and CYP4A2 using bicistronic vectors in vascular cells and tissues.

  The Journal of pharmacology and experimental therapeutics 20041201

• TREK-1 K+ channels couple angiotensin II receptors to membrane depolarization and aldosterone secretion in bovine adrenal glomerulosa cells.

  American journal of physiology. Endocrinology and metabolism 20041201

• Preferential inhibition of paraoxonase activity of human paraoxonase 1 by negatively charged lipids.

  Journal of lipid research 20041201

• Cyclooxygenase-2-derived endogenous prostacyclin enhances mouse embryo hatching.

  Human reproduction (Oxford, England) 20041201

• Effects of synthetic sphingosine-1-phosphate analogs on arachidonic acid metabolism and cell death.

  Biochemical pharmacology 20041201

• ARC channels: a novel pathway for receptor-activated calcium entry.

  Physiology (Bethesda, Md.) 20041201

• Dietary supplementation with arachidonic acid in tilapia (Oreochromis mossambicus) reveals physiological effects not mediated by prostaglandins.

  General and comparative endocrinology 20041201

• Mechanism of the attenuation of proteolysis-inducing factor stimulated protein degradation in muscle by beta-hydroxy-beta-methylbutyrate.

  Cancer research 20041201

• New perspectives in the studies on endocannabinoid and cannabis: a role for the endocannabinoid-arachidonic acid pathway in drug reward and long-lasting relapse to drug taking.

  Journal of pharmacological sciences 20041201

• [Inhibition of the arachidonic acid cascade by aza-2-aryl-1,4-naphthoquinone derivatives].

  Die Pharmazie 20041201

• Mast cell--pituitary interaction: modulation by serine phospholipids.

  Die Pharmazie 20041201

• Evidence that arachidonic acid derived from neutrophils and prostaglandin E2 are associated with the induction of acute lung inflammation by lipopolysaccharide of Escherichia coli.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20041201

• Development of a fluorescent high throughput assay for tau aggregation.

  Assay and drug development technologies 20041201

• The 'alphabet' of rheumatoid arthritis treatment.

  Medsurg nursing : official journal of the Academy of Medical-Surgical Nurses 20041201

• Effect of vitamin E on gene expression changes in diet-related carcinogenesis.

  Annals of the New York Academy of Sciences 20041201

• Effect of vitamin E on prostacyclin (PGI2) and prostaglandin (PG) E2 production by human aorta endothelial cells: mechanism of action.

  Annals of the New York Academy of Sciences 20041201

• Angiotensin II stimulates arachidonic acid release from bone marrow stromal cells.

  Journal of the renin-angiotensin-aldosterone system : JRAAS 20041201

• Cyclooxygenase-2 induction and prostaglandin E2 accumulation in squamous cell carcinoma as a consequence of epidermal growth factor receptor activation by imatinib mesylate.

  Journal of experimental therapeutics & oncology 20041201

• Prostanoid DP1 receptor agonist inhibits the pruritic activity in NC/Nga mice with atopic dermatitis.

  European journal of pharmacology 20041128

• The alpha isoform of diacylglycerol kinase exhibits arachidonoyl specificity with alkylacylglycerol.

  Biochemistry 20041123

• Cytosolic phospholipase A2 Group IValpha but not secreted phospholipase A2 Group IIA, V, or X induces interleukin-8 and cyclooxygenase-2 gene and protein expression through peroxisome proliferator-activated receptors gamma 1 and 2 in human lung cells.

  The Journal of biological chemistry 20041119

• Can selenium prevent colorectal cancer? A signpost from epidemiology.

  Journal of the National Cancer Institute 20041117

• Covalent binding of isoketals to ethanolamine phospholipids.

  Free radical biology & medicine 20041115

• Translocation of phospholipase A2 to membranes by oxidized LDL and hydroxyoctadecadienoic acid to contribute to cholesteryl ester formation.

  Biochimica et biophysica acta 20041108

• Contribution of lipid second messengers to the regulation of phosphatidylcholine synthesis during cell cycle re-entry.

  Biochimica et biophysica acta 20041108

• Amyloid beta(1-42) and its beta(25-35) fragment induce activation and membrane translocation of cytosolic phospholipase A2 in bovine retina capillary pericytes.

  Biochimica et biophysica acta 20041108

• Lysophosphatidic acid is a mediator of Trp-Lys-Tyr-Met-Val-d-Met-induced calcium influx.

  Biochemical and biophysical research communications 20041105

• Plasma AA and DHA levels are not compromised in newly diagnosed gestational diabetic women.

  European journal of clinical nutrition 20041101

• A cyclooxygenase metabolite of anandamide causes inhibition of interleukin-2 secretion in murine splenocytes.

  The Journal of pharmacology and experimental therapeutics 20041101

• 2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand, induces the migration of EoL-1 human eosinophilic leukemia cells and human peripheral blood eosinophils.

  Journal of leukocyte biology 20041101

• Fatty acid binding proteins stabilize leukotriene A4: competition with arachidonic acid but not other lipoxygenase products.

  Journal of lipid research 20041101

• Requirement of PPARalpha in maintaining phospholipid and triacylglycerol homeostasis during energy deprivation.

  Journal of lipid research 20041101

• Altered PDGF-BB-induced p38 MAP kinase activation in diabetic vascular smooth muscle cells: roles of protein kinase C-delta.

  Arteriosclerosis, thrombosis, and vascular biology 20041101

• Defects in the prostaglandin system--what is known?

  Prostaglandins, leukotrienes, and essential fatty acids 20041101

• Ischemic preconditioning: emerging evidence, controversy, and translational trials.

  International journal of cardiology 20041101

• Caveolae and EDHF production.

  Cardiovascular research 20041101

• Cholesterol- and caveolin-rich membrane domains are essential for phospholipase A2-dependent EDHF formation.

  Cardiovascular research 20041101

• Protein kinase C delta is required for p47phox phosphorylation and translocation in activated human monocytes.

  Journal of immunology (Baltimore, Md. : 1950) 20041101

• Mitochondrial dysfunction is a primary event in renal cell oxalate toxicity.

  Kidney international 20041101

• Low-density lipoprotein inhibits receptor-mediated prostaglandin synthesis without affecting calcium and arachidonic acid mobilization in human endothelial cells.

  Journal of cardiovascular pharmacology 20041101

• In vivo imaging detects a transient increase in brain arachidonic acid metabolism: a potential marker of neuroinflammation.

  Journal of neurochemistry 20041101

• Expression of cytosolic phospholipase A2 alpha in murine C12 cells, a variant of L929 cells, induces arachidonic acid release in response to phorbol myristate acetate and Ca2+ ionophores, but not to tumor necrosis factor-alpha.

  Journal of pharmacological sciences 20041101

• Arachidonic acid regulation of steroid synthesis: new partners in the signaling pathway of steroidogenic hormones.

  Endocrine research 20041101

• Tyrosine phosphates act on steroidogenesis through the activation of arachidonic acid release.

  Endocrine research 20041101

• Multiple contributions from long-chain fatty acid metabolism in Y-1 and MA-10 cells.

  Endocrine research 20041101

• Dose dependent accretion of docosahexaenoic acid (DHA) in cardiac membranes of rats fed egg yolk powder enriched in DHA.

  Cellular and molecular biology (Noisy-le-Grand, France) 20041101

• Docosahexaenoic acid-enriched egg phospholipids supplementation induces accretion of arachidonic acid in rat blood lipids.

  Cellular and molecular biology (Noisy-le-Grand, France) 20041101

• Overexpression of 12/15-lipoxygenase, an ortholog of human 15-lipoxygenase-1, in the prostate tumors of TRAMP mice.

  Neoplasia (New York, N.Y.) 20041101

• Activation of the orphan nuclear receptor RORalpha counteracts the proliferative effect of fatty acids on prostate cancer cells: crucial role of 5-lipoxygenase.

  International journal of cancer 20041020

• Schistosoma mansoni fatty acid binding protein: specificity and functional control as revealed by crystallographic structure.

  Biochemistry 20041019

• Eccentric exercise alters muscle sensory motor control through the release of inflammatory mediators.

  Brain research 20041015

• Risk of coronary artery disease associated with polymorphism of the cytochrome P450 epoxygenase CYP2J2.

  Circulation 20041012

• Crystal structure of arachidonic acid bound to a mutant of prostaglandin endoperoxide H synthase-1 that forms predominantly 11-hydroperoxyeicosatetraenoic acid.

  The Journal of biological chemistry 20041008

• Functional expression of TREK-2 in insulin-secreting MIN6 cells.

  Biochemical and biophysical research communications 20041008

• Arachidonic acid relaxes human pulmonary arteries through K+ channels and nitric oxide pathways.

  European journal of pharmacology 20041006

• Oxalate inhibits renal proximal tubule cell proliferation via oxidative stress, p38 MAPK/JNK, and cPLA2 signaling pathways.

  American journal of physiology. Cell physiology 20041001

• Acetylcholine-induced relaxation and hyperpolarization in small bovine adrenal cortical arteries: role of cytochrome P450 metabolites.

  Endocrinology 20041001

• Potency of arachidonic acid in polyunsaturated fatty acid-induced death of human monocyte-macrophages: implications for atherosclerosis.

  Prostaglandins, leukotrienes, and essential fatty acids 20041001

• Statin treatment alters serum n-3 and n-6 fatty acids in hypercholesterolemic patients.

  Prostaglandins, leukotrienes, and essential fatty acids 20041001

• Mass spectrometric quantitation of deoxyguanosine and leukotriene A4-deoxyguanosine adducts of DNA.

  Analytical biochemistry 20041001

• Lipoxins in asthma: potential therapeutic mediators on bronchial inflammation?

  Allergy 20041001

• Protective effect of N-acetyl-serotonin on the nonenzymatic lipid peroxidation in rat testicular microsomes and mitochondria.

  Journal of pineal research 20041001

• PTH and phospholipase A2 in the aging process of intestinal cells.

  Journal of cellular biochemistry 20041001

• Abnormal cell-specific expressions of certain protein kinase C isoenzymes in peripheral mononuclear cells of patients with systemic lupus erythematosus: effect of corticosteroid application.

  Scandinavian journal of immunology 20041001

• 12-Lipoxygenase plays a key role in cell death caused by glutathione depletion and arachidonic acid in rat oligodendrocytes.

  The European journal of neuroscience 20041001

• Investigation of the contribution of histidine 119 to the conduction of protons through human Nox2.

  European journal of biochemistry 20041001

• Differential effects of RU486 reveal distinct mechanisms for glucocorticoid repression of prostaglandin E release.

  European journal of biochemistry 20041001

• Structure-activity relationship studies on chalcone derivatives: potent inhibition of platelet aggregation.

  The Journal of pharmacy and pharmacology 20041001

• Peroxisome proliferator-activated receptor and farnesoid X receptor ligands differentially regulate sebaceous differentiation in human sebaceous gland organ cultures in vitro.

  The British journal of dermatology 20041001

• Inherited defects in platelet signaling mechanisms.

  Seminars in thrombosis and hemostasis 20041001

• Evidence for placental transfer of lipids during gestation in the viviparous lizard, Pseudemoia entrecasteauxii.

  Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20041001

• Effect of conjugated linoleic acid on Delta-5 desaturase activity in yeast transformed with fungal Delta-5 desaturase gene.

  Molecular and cellular biochemistry 20041001

• Changes in renal haemodynamics induced by indomethacin in the rat involve cytochrome P450 arachidonic acid-dependent epoxygenases.

  Clinical and experimental pharmacology & physiology 20041001

• The effect of anionic amphiphiles on the recruitment of Rac in neutrophils.

  Journal of biochemistry 20041001

• [Enzymes involved in arachidonic acid metabolism].

  Arerugi = [Allergy] 20041001

• Polyunsaturated fatty acids inhibit mouse hepatic glucocorticoid receptor activation in vitro.

  Indian journal of biochemistry & biophysics 20041001

• Identification of native rat cerebellar granule cell currents due to background K channel KCNK5 (TASK-2).

  Brain research. Molecular brain research 20040928

• Role of group VIA calcium-independent phospholipase A2 in arachidonic acid release, phospholipid fatty acid incorporation, and apoptosis in U937 cells responding to hydrogen peroxide.

  The Journal of biological chemistry 20040924

• Neurobiology: feeding the brain.

  Nature 20040909

• Calcium transients in astrocyte endfeet cause cerebrovascular constrictions.

  Nature 20040909

• gp91phox-dependent expression of platelet CD40 ligand.

  Circulation 20040907

• Beating ischemia: a new feat of EETs?

  Circulation research 20040903

• Modulation of arachidonic acid metabolism by curcumin and related beta-diketone derivatives: effects on cytosolic phospholipase A(2), cyclooxygenases and 5-lipoxygenase.

  Carcinogenesis 20040901

• CYP2C44, a new murine CYP2C that metabolizes arachidonic acid to unique stereospecific products.

  The Journal of pharmacology and experimental therapeutics 20040901

• Effect of BM-573 [N-terbutyl-N'-[2-(4'-methylphenylamino)-5-nitro-benzenesulfonyl]urea], a dual thromboxane synthase inhibitor and thromboxane receptor antagonist, in a porcine model of acute pulmonary embolism.

  The Journal of pharmacology and experimental therapeutics 20040901

• Growth factors induce monocyte binding to vascular smooth muscle cells: implications for monocyte retention in atherosclerosis.

  American journal of physiology. Cell physiology 20040901

• Leptin augments alveolar macrophage leukotriene synthesis by increasing phospholipase activity and enhancing group IVC iPLA2 (cPLA2gamma) protein expression.

  American journal of physiology. Lung cellular and molecular physiology 20040901

• Hydrogen peroxide generated at the level of mitochondria in response to peroxynitrite promotes U937 cell death via inhibition of the cytoprotective signalling mediated by cytosolic phospholipase A2.

  Cell death and differentiation 20040901

• Glucuronidation of oxidized fatty acids and prostaglandins B1 and E2 by human hepatic and recombinant UDP-glucuronosyltransferases.

  Journal of lipid research 20040901

• Determination of trans-arachidonic acid isomers in human blood plasma.

  Analytical biochemistry 20040901

• Arachidonic acid-induced carbon-centered radicals and phospholipid peroxidation in cyclo-oxygenase-2-transfected PC12 cells.

  Journal of neurochemistry 20040901

• Structural and functional comparison of 15S- and 15R-specific cyclooxygenases from the coral Plexaura homomalla.

  European journal of biochemistry 20040901

• COX-2 Regulates the insulin-like growth factor I-induced potentiation of Zn(2+)-toxicity in primary cortical culture.

  Molecular pharmacology 20040901

• Arachidonic acid reduces the stress response of gilthead seabream Sparus aurata L.

  The Journal of experimental biology 20040901

• Anti-platelet effect of aspirin is substantially reduced after administration of heparin during carotid endarterectomy.

  Journal of vascular surgery 20040901

• Brain incorporation of 11C-arachidonic acid, blood volume, and blood flow in healthy aging: a study with partial-volume correction.

  Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20040901

• Raloxifene and hormone replacement therapy increase arachidonic acid and docosahexaenoic acid levels in postmenopausal women.

  The Journal of endocrinology 20040901

• Antiinflammatory, analgesic and antioxidant activities of the fruit of Foeniculum vulgare.

  Fitoterapia 20040901

• Platelet hyperreactivity in hemodialysis patients with frequently occluded vascular access.

  Thrombosis and haemostasis 20040901

• Alterations of activities of cytosolic phospholipase A2 and arachidonic acid-metabolizing enzymes in di-(2-ethylhexyl)phthalate-induced testicular atrophy.

  The Journal of veterinary medical science 20040901

• Influence of dietary conjugated linoleic Acid and fat source on body fat and apoptosis in mice.

  Obesity research 20040901

• Role of the Pyk2-MAP kinase-cPLA2 signaling pathway in shear-dependent platelet aggregation.

  Annals of biomedical engineering 20040901

• [MAP kinase signal pathway in hyperglycemia-induced congenital neural tube defects].

  Yi chuan = Hereditas 20040901

• Interaction between ferric ions, phospholipid hydroperoxides, and the lipid phosphate moiety at physiological pH.

  Lipids 20040901

• Comparison of in vitro-activity of commonly used topical glucocorticoids on cytokine- and phospholipase inhibition.

  European journal of medical research 20040831

• Suppression of cyclooxygenase-2 overexpression by 15S-hydroxyeicosatrienoic acid in androgen-dependent prostatic adenocarcinoma cells.

  International journal of cancer 20040820

• Aspirin 'allergy' and resistance.

  Journal of the American College of Cardiology 20040818

• Decreased lung tumorigenesis in mice genetically deficient in cytosolic phospholipase A2.

  Carcinogenesis 20040801

• Essential role of EDHF in the initiation and maintenance of adrenergic vasomotion in rat mesenteric arteries.

  American journal of physiology. Heart and circulatory physiology 20040801

• Endocannabinoid system modulates relapse to methamphetamine seeking: possible mediation by the arachidonic acid cascade.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20040801

• Lipoxygenase-dependent superoxide release in skeletal muscle.

  Journal of applied physiology (Bethesda, Md. : 1985) 20040801

• Calmidazolium and arachidonate activate a calcium entry pathway that is distinct from store-operated calcium influx in HeLa cells.

  The Biochemical journal 20040801

• Phosphatidylinositol transfer protein alpha regulates growth and apoptosis of NIH3T3 cells: involvement of a cannabinoid 1-like receptor.

  Journal of lipid research 20040801

• Human CYP4F3s are the main catalysts in the oxidation of fatty acid epoxides.

  Journal of lipid research 20040801

• Effects of an n-3-deficient diet on brain, retina, and liver fatty acyl composition in artificially reared rats.

  Journal of lipid research 20040801

• In vivo and in vitro anti-inflammatory activity of Mangifera indica L. extract (VIMANG).

  Pharmacological research 20040801

• Archetype signals in plants: the phytoprostanes.

  Current opinion in plant biology 20040801

• Arachidonic acid increases choline acetyltransferase activity in spinal cord neurons through a protein kinase C-mediated mechanism.

  Journal of neurochemistry 20040801

• Metabolism of retinoids and arachidonic acid by human and mouse cytochrome P450 1b1.

  Drug metabolism and disposition: the biological fate of chemicals 20040801

• Consequences of eicosapentaenoic acid (n-3) and arachidonic acid (n-6) supplementation on mast cell mediators.

  Journal of animal physiology and animal nutrition 20040801

• Biological variation of plasma F2-isoprostane-III and arachidonic acid in healthy individuals.

  Clinical chemistry 20040801

• Recent development in the field of dual COX / 5-LOX inhibitors.

  Mini reviews in medicinal chemistry 20040801

• Modulation of the arachidonic cascade with omega3 fatty acids or analogues: potential therapeutic benefits.

  Mini reviews in medicinal chemistry 20040801

• Alteration of prostaglandin production and agonist responsiveness by n-6 polyunsaturated fatty acids in endometrial cells from late-gestation ewes.

  The Journal of endocrinology 20040801

• Docosahexaenoic acid promotes neurite growth in hippocampal neurons.

  Journal of neurochemistry 20040801

• Chemo-enzymatic synthesis of N-arachidonoyl glycine.

  Biotechnology letters 20040801

• Dietary patterns and blood fatty acid composition in children with attention-deficit hyperactivity disorder in Taiwan.

  The Journal of nutritional biochemistry 20040801

• Platelet activation in type 2 diabetes mellitus.

  Journal of thrombosis and haemostasis : JTH 20040801

• Polyunsaturated fatty acids are FXR ligands and differentially regulate expression of FXR targets.

  DNA and cell biology 20040801

• Biosynthesis of oleic, arachidonic and docosahexaenoic acids from their C18 precursors in the yolk sac membrane of the avian embryo.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20040801

• In vitro effects of risperidone and 9-hydroxy-risperidone on human platelet function, plasma coagulation, and fibrinolysis.

  Clinical therapeutics 20040801

• Close functional coupling between Ca2+ release-activated Ca2+ channels, arachidonic acid release, and leukotriene C4 secretion.

  The Journal of biological chemistry 20040716

• Inhibition of nitric-oxide synthase-I (NOS-I)-dependent nitric oxide production by lipopolysaccharide plus interferon-gamma is mediated by arachidonic acid. Effects on NFkappaB activation and late inducible NOS expression.

  The Journal of biological chemistry 20040716

• Synthesis and evaluation of substrate-mimicking cytosolic phospholipase A2 inhibitors--reducing the lipophilicity of the arachidonyl chain isostere.

  Bioorganic & medicinal chemistry letters 20040716

• The effect of chronic lithium on arachidonic acid release and metabolism in rat brain does not involve secretory phospholipase A2 or lipoxygenase/cytochrome P450 pathways.

  Brain research bulletin 20040715

• Identification and localization of an arachidonic acid-sensitive potassium channel in the cochlea.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20040714

• Colon carcinoma cell growth is associated with prostaglandin E2/EP4 receptor-evoked ERK activation.

  The Journal of biological chemistry 20040709

• Functional expression of TRESK-2, a new member of the tandem-pore K+ channel family.

  The Journal of biological chemistry 20040702

• TXAS-deleted mice exhibit normal thrombopoiesis, defective hemostasis, and resistance to arachidonate-induced death.

  Blood 20040701

• Angiotensin II-induced ERK1/ERK2 activation and protein synthesis are redox-dependent in glomerular mesangial cells.

  The Biochemical journal 20040701

• Inhibition of the formation of EETs and 20-HETE with 1-aminobenzotriazole attenuates pressure natriuresis.

  American journal of physiology. Regulatory, integrative and comparative physiology 20040701

• Polyunsaturated fatty acids including docosahexaenoic and arachidonic acid bind to the retinoid X receptor alpha ligand-binding domain.

  Molecular & cellular proteomics : MCP 20040701

• Comparison of the fatty-acid compositions of prey items and yolks of Australian insectivorous scincid lizards.

  Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20040701

• TRPV channels and modulation by hepatocyte growth factor/scatter factor in human hepatoblastoma (HepG2) cells.

  Cell calcium 20040701

• PGE2 stimulates Cl- secretion in murine M-1 cortical collecting duct cells in an autocrine manner.

  Pflugers Archiv : European journal of physiology 20040701

• Balance between PGD synthase and PGE synthase is a major determinant of atherosclerotic plaque instability in humans.

  Arteriosclerosis, thrombosis, and vascular biology 20040701

• Effect of COX-1/COX-2 inhibition versus selective COX-2 inhibition on coronary vasodilator responses to arachidonic acid and acetylcholine.

  Pharmacology 20040701

• On the role of the islets of Langerhans in pancreatic cancer.

  Histology and histopathology 20040701

• In humans, the seasonal variation in poly-unsaturated fatty acids is related to the seasonal variation in violent suicide and serotonergic markers of violent suicide.

  Prostaglandins, leukotrienes, and essential fatty acids 20040701

• Antiplatelet effect of green tea catechins: a possible mechanism through arachidonic acid pathway.

  Prostaglandins, leukotrienes, and essential fatty acids 20040701

• Synthesis of (5Z,8Z,11Z,14Z)-18- and 19-azidoeicosa-5,8,11,14-tetraenoic acids and their [5,6,8,9,11,12,14,15-3H8]-analogues through a common synthetic route.

  Chemistry and physics of lipids 20040701

• 20-HETE or EETs: which arachidonic acid metabolite regulates proximal tubule transporters and contributes to pressure natriuresis?

  American journal of physiology. Regulatory, integrative and comparative physiology 20040701

• Subtype specific internalization of P2Y1 and P2Y2 receptors induced by novel adenosine 5'-O-(1-boranotriphosphate) derivatives.

  British journal of pharmacology 20040701

• The effect of isoniazid on CYP2E1- and CYP4A-mediated hydroxylation of arachidonic acid in the rat liver and kidney.

  Drug metabolism and disposition: the biological fate of chemicals 20040701

• Signaling mechanisms mediated by G-protein coupled receptors in human platelets.

  Acta pharmacologica Sinica 20040701

• Platelet inhibition by aspirin is diminished in patients during carotid surgery: a form of transient aspirin resistance?

  Thrombosis and haemostasis 20040701

• Endotoxin-induced uveitis in cyclooxygenase-2-deficient mice.

  Investigative ophthalmology & visual science 20040701

• Effect of male sex and obesity on platelet arachidonic acid in spontaneous hypertensive heart failure rats.

  Experimental biology and medicine (Maywood, N.J.) 20040701

• Pharmacological and histopathological characterization of Bothrops lanceolatus (Fer de lance) venom-induced edema.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20040701

• [Astrocytic cytochromes p450: an enzyme subfamily critical for brain metabolism and neuroprotection].

  Revue neurologique 20040701

• Autoxidative transformation of chiral omega6 hydroxy linoleic and arachidonic acids to chiral 4-hydroxy-2E-nonenal.

  Chemical research in toxicology 20040701

• 17-Beta estradiol enhances prostaglandin E2 production in human U937-derived macrophages.

  Molecular and cellular biochemistry 20040701

• Platelet 12-lipoxygenase activation via glycoprotein VI: involvement of multiple signaling pathways in agonist control of H(P)ETE synthesis.

  Circulation research 20040625

• AHNAK-mediated activation of phospholipase C-gamma1 through protein kinase C.

  The Journal of biological chemistry 20040618

• An excised patch membrane sensor for arachidonic acid released in mouse hippocampal slices under stimulation of L-glutamate.

  Analytical biochemistry 20040615

• Arachidonic acid release from mammalian cells transfected with human groups IIA and X secreted phospholipase A(2) occurs predominantly during the secretory process and with the involvement of cytosolic phospholipase A(2)-alpha.

  The Journal of biological chemistry 20040611

• Arachidonic acid released by phospholipase A(2) activation triggers Ca(2+)-dependent apoptosis through the mitochondrial pathway.

  The Journal of biological chemistry 20040611

• Acyl-CoA synthetase 2 overexpression enhances fatty acid internalization and neurite outgrowth.

  The Journal of biological chemistry 20040604

• Strain-related variations of AMPA receptor modulation by calcium-dependent mechanisms in the hippocampus: contribution of lipoxygenase metabolites of arachidonic acid.

  Brain research 20040604

• Involvement of the mitogen-activated protein kinase cascade in peroxynitrite-mediated arachidonic acid release in vascular smooth muscle cells.

  American journal of physiology. Cell physiology 20040601

• 5-HT induces an arachidonic acid-sensitive calcium influx in rat small intrapulmonary artery.

  American journal of physiology. Lung cellular and molecular physiology 20040601

• Excess nitric oxide decreases cytochrome P-450 2J4 content and P-450-dependent arachidonic acid metabolism in lungs of rats with acute pneumonia.

  American journal of physiology. Lung cellular and molecular physiology 20040601

• Lysophosphatidylcholine and 7-oxocholesterol modulate Ca2+ signals and inhibit the phosphorylation of endothelial NO synthase and cytosolic phospholipase A2.

  The Biochemical journal 20040601

• Cytochrome P450 epoxygenases as EDHF synthase(s).

  Pharmacological research 20040601

• Ascorbate-mediated enhancement of reactive oxygen species generation from polymorphonuclear leukocytes: modulatory effect of nitric oxide.

  Journal of leukocyte biology 20040601

• Role of an aprotinin-sensitive protease in protein kinase Calpha-mediated activation of cytosolic phospholipase A2 by calcium ionophore (A23187) in pulmonary endothelium.

  Cellular signalling 20040601

• Involvement of arachidonic acid cascade in working memory impairment induced by interleukin-1 beta.

  Neuropharmacology 20040601

• Antimicrobial activity of clofazimine is not dependent on mycobacterial C-type phospholipases.

  The Journal of antimicrobial chemotherapy 20040601

• Incorporation of arachidonic and linoleic acid hydroperoxides into cultured human umbilical vein endothelial cells.

  Prostaglandins, leukotrienes, and essential fatty acids 20040601

• Production of very long chain polyunsaturated omega-3 and omega-6 fatty acids in plants.

  Nature biotechnology 20040601

• K317, R319, and E320 within the proximal C-terminus of the bradykinin B2 receptor form a motif important for phospholipase C and phospholipase A2 but not connective tissue growth factor related signaling.

  Journal of cellular biochemistry 20040601

• Platelet-derived growth factor-induced arachidonic acid release for enhancement of prostaglandin E(2) synthesis in human gingival fibroblasts pretreated with interleukin-1beta.

  Journal of cellular biochemistry 20040601

• Effects of esculentoside A on production of interleukin-1, 2, and prostaglandin E2.

  Acta pharmacologica Sinica 20040601

• Prostacyclin release and receptor activation: differential control of human pulmonary venous and arterial tone.

  British journal of pharmacology 20040601

• From alpha to omega-producing essential fatty acids in plants.

  Nature biotechnology 20040601

• Cytochrome P450 in neurological disease.

  Current drug metabolism 20040601

• Role of cytochrome P450 metabolites of arachidonic acid in hypertension.

  Current drug metabolism 20040601

• The influence of different combinations of gamma-linolenic acid, stearidonic acid and EPA on immune function in healthy young male subjects.

  The British journal of nutrition 20040601

• Receptor-independent depression of DA and 5-HT uptake by cannabinoids in rat neocortex--involvement of Na(+)/K(+)-ATPase.

  Neurochemistry international 20040601

• Synthesis of (2E)-2-methyl-3-(4-([4-(quinolin-2-ylmethoxy)phenyl]sulfanyl)phenyl)prop-2-enoic acid (VUFB 20609) and 2-methyl-3-(4-([4-(quinolin-2-ylmethoxy)phenyl]sulfanyl)phenyl)propanoic acid (VUFB 20584) as potential antileukotrienic agents.

  The Journal of pharmacy and pharmacology 20040601

• [Prostaglandin/bradykinin].

  Nihon rinsho. Japanese journal of clinical medicine 20040601

• [Effect of arachidonic acid peroxidation products on the development of gastroesophageal reflux disease].

  Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20040601

• Ischaemia-reperfusion injury in the isolated haemoperfused bovine uterus: an in vitro model of acute inflammation.

  Alternatives to laboratory animals : ATLA 20040601

• Hydrocortisone and dexamethasone in very deformable drug carriers have increased biological potency, prolonged effect, and reduced therapeutic dosage.

  Biochimica et biophysica acta 20040527

• Anionic amphiphile and phospholipid-induced conformational changes in human neutrophil flavocytochrome b observed by fluorescence resonance energy transfer.

  Biochimica et biophysica acta 20040527

• Effects of anti-inflammatory cytokine agent (FR167653) and serine protease inhibitor on warm ischemia-reperfusion injury of the liver graft.

  Transplantation 20040527

• Fcgamma RI-triggered generation of arachidonic acid and eicosanoids requires iPLA2 but not cPLA2 in human monocytic cells.

  The Journal of biological chemistry 20040521

• Sites of protein kinase A activation of the human ClC-2 Cl(-) channel.

  The Journal of biological chemistry 20040521

• Resveratrol is a peroxidase-mediated inactivator of COX-1 but not COX-2: a mechanistic approach to the design of COX-1 selective agents.

  The Journal of biological chemistry 20040521

• Anti-HCV activities of selective polyunsaturated fatty acids.

  Biochemical and biophysical research communications 20040521

• Association of a long-chain fatty acid-CoA ligase 4 gene polymorphism with depression and with enhanced niacin-induced dermal erythema.

  American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 20040515

• Eicosanoids in cystic fibrosis.

  The New England journal of medicine 20040506

• Eicosanoids in cystic fibrosis.

  The New England journal of medicine 20040506

• Metabolomic analysis of adrenal lipids during hypoxia in the neonatal rat: implications in steroidogenesis.

  American journal of physiology. Endocrinology and metabolism 20040501

• Adenovirus-mediated delivery and expression of a cAMP-dependent protein kinase inhibitor gene to BEAS-2B epithelial cells abolishes the anti-inflammatory effects of rolipram, salbutamol, and prostaglandin E2: a comparison with H-89.

  The Journal of pharmacology and experimental therapeutics 20040501

• Modification of LDL with human secretory phospholipase A(2) or sphingomyelinase promotes its arachidonic acid-releasing propensity.

  Journal of lipid research 20040501

• Differential effect of phosphodiesterase IV inhibitor RP73401 on various inflammatory and immune responses relevent to rheumatoid arthritis.

  Pharmacological research 20040501

• Phospholipid metabolism is required for M1 muscarinic inhibition of N-type calcium current in sympathetic neurons.

  European biophysics journal : EBJ 20040501

• Intracellular oxidation by human glioma cell populations: effect of arachidonic acid.

  Prostaglandins, leukotrienes, and essential fatty acids 20040501

• Characterization of the PGI2/IP system in cultured rat mesangial cells.

  Prostaglandins, leukotrienes, and essential fatty acids 20040501

• Rapid alterations of serum fatty acids with the intravenous administration of an arachidonate solution.

  Prostaglandins, leukotrienes, and essential fatty acids 20040501

• Alteration of plasma total F2-isoprostanes before and after hemodialysis in end-stage renal disease patients.

  Prostaglandins, leukotrienes, and essential fatty acids 20040501

• Inhibition of the arachidonic acid cascade by norathyriol via blockade of cyclooxygenase and lipoxygenase activity in neutrophils.

  Naunyn-Schmiedeberg's archives of pharmacology 20040501

• Protein diet and hypercalciuria.

  Kidney international 20040501

• Soluble epoxide hydrolase inhibition protects the kidney from hypertension-induced damage.

  Journal of the American Society of Nephrology : JASN 20040501

• Inhibition of the arachidonic acid metabolism blocks endothelial cell migration and induces apoptosis.

  Acta neurochirurgica 20040501

• A novel modification of the Thrombelastograph assay, isolating platelet function, correlates with optical platelet aggregation.

  The Journal of laboratory and clinical medicine 20040501

• Erythrocyte-derived measures of membrane lipid composition in healthy men: associations with arachidonic acid at low to moderate but not high insulin sensitivity.

  Metabolism: clinical and experimental 20040501

• Oxidative stress and cell signalling.

  Current medicinal chemistry 20040501

• New developments on thromboxane and prostacyclin modulators part I: thromboxane modulators.

  Current medicinal chemistry 20040501

• Inflammatory resolution: new opportunities for drug discovery.

  Nature reviews. Drug discovery 20040501

• Fatty acid-mediated inhibition of IL-12 production by murine macrophages is independent of PPARgamma.

  The British journal of nutrition 20040501

• Docosahexaenoic acid-enriched egg consumption induces accretion of arachidonic acid in erythrocytes of elderly patients.

  The British journal of nutrition 20040501

• Dietary N-6 and N-3 polyunsaturated fatty acids and prostate cancer risk: a review of epidemiological and experimental evidence.

  Cancer causes & control : CCC 20040501

• Differential expression of cytochrome P450 isoforms in the lungs of septic animals.

  Critical care medicine 20040501

• 1alpha,25(OH)2D3 and parathyroid hormone (PTH) signaling in rat intestinal cells: activation of cytosolic PLA2.

  The Journal of steroid biochemistry and molecular biology 20040501

• Cytosolic phospholipase A2 translocates to forming phagosomes during phagocytosis of zymosan in macrophages.

  The Journal of biological chemistry 20040430

• B-Myb-dependent regulation of c-Myc expression by cytosolic phospholipase A2.

  The Journal of biological chemistry 20040423

• The arachidonate-dependent cytoprotective signaling evoked by peroxynitrite is a general response of the monocyte/macrophage lineage.

  Biochemical and biophysical research communications 20040416

• Myofilament anchoring of protein kinase C-epsilon in cardiac myocytes.

  Journal of cell science 20040415

• Arachidonic and eicosapentaenoic acid metabolism by human CYP1A1: highly stereoselective formation of 17(R),18(S)-epoxyeicosatetraenoic acid.

  Biochemical pharmacology 20040415

• Cyclooxygenase 1-dependent production of F2-isoprostane and changes in redox status during warm renal ischemia-reperfusion.

  Free radical biology & medicine 20040415

• Cyclooxygenase-2 activation mediates the proangiogenic effect of nitric oxide in colorectal cancer.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20040415

• Interfacial enzymology of parvovirus phospholipases A2.

  The Journal of biological chemistry 20040409

• Stimulation of myelin proteolipid protein gene expression by eicosapentaenoic acid in C6 glioma cells.

  Neurochemistry international 20040401

• Presynaptic kainate receptors modulating glutamatergic transmission in the rat hippocampus are inhibited by arachidonic acid.

  Neurochemistry international 20040401

• Signaling cascade of ANG II-induced inhibition of alpha-MG uptake in renal proximal tubule cells.

  American journal of physiology. Renal physiology 20040401

• ET-1 induces cortical spreading depression via activation of the ETA receptor/phospholipase C pathway in vivo.

  American journal of physiology. Heart and circulatory physiology 20040401

• Linoleic acid induces interleukin-8 production by Crohn's human intestinal smooth muscle cells via arachidonic acid metabolites.

  American journal of physiology. Gastrointestinal and liver physiology 20040401

• Epoxide hydrolases in the rat epididymis: possible roles in xenobiotic and endogenous fatty acid metabolism.

  Toxicological sciences : an official journal of the Society of Toxicology 20040401

• Elevated BSC-1 and ROMK expression in Dahl salt-sensitive rat kidneys.

  Hypertension (Dallas, Tex. : 1979) 20040401

• Evidence for a role of the arachidonic acid cascade in affective disorders: a review.

  Bipolar disorders 20040401

• Modulation of trigeminal sensory neuron activity by the dual cannabinoid-vanilloid agonists anandamide, N-arachidonoyl-dopamine and arachidonyl-2-chloroethylamide.

  British journal of pharmacology 20040401

• Activity-driven sharpening of the retinotectal projection: the search for retrograde synaptic signaling pathways.

  Journal of neurobiology 20040401

• Differential regulation of IL-4 expression and degranulation by anti-allergic olopatadine in rat basophilic leukemia (RBL-2H3) cells.

  Biochemical pharmacology 20040401

• Activation of phospholipase C-gamma1 in human keratinocytes by hyperosmolar shock without enzyme phosphorylation.

  Archives of dermatological research 20040401

• HPLC assay with UV spectrometric detection for the evaluation of inhibitors of cytosolic phospholipase A2.

  Journal of pharmaceutical and biomedical analysis 20040401

• Association of adipose tissue arachidonic acid content with BMI and overweight status in children from Cyprus and Crete.

  The British journal of nutrition 20040401

• Dietary supplementation with olive oil leads to improved lipoprotein spectrum and lower n-6 PUFAs in elderly subjects.

  Medical science monitor : international medical journal of experimental and clinical research 20040401

• Regulation of the specific release of arachidonic acid by cytosolic phospholipase A2.

  Prostaglandins, leukotrienes, and essential fatty acids 20040401

• Acetylsalicylic acid, diclofenac, and lornoxicam, but not rofecoxib, affect platelet CD 62 expression.

  Anesthesia and analgesia 20040401

• Vitamin E supplementation increases polyunsaturated fatty acids of RBC membrane in HCV-infected patients.

  Nutrition (Burbank, Los Angeles County, Calif.) 20040401

• Do cats need arachidonic acid in the diet for reproduction?

  Journal of animal physiology and animal nutrition 20040401

• Dietary conjugated linoleic acid increases the mRNA ratio of Bax/Bcl-2 in the colonic mucosa of rats.

  The Journal of nutritional biochemistry 20040401

• Biosynthesis and dietary uptake of polyunsaturated fatty acids by piezophilic bacteria.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20040401

• Evaluation of effects of rofecoxib on platelet function in an in vitro model of thrombosis with circulating human blood.

  European journal of clinical investigation 20040401

• Oxidative stress and neuroinflammation in Alzheimer's disease and amyotrophic lateral sclerosis: common links and potential therapeutic targets.

  Journal of Alzheimer's disease : JAD 20040401

• 2-Arachidonoylglycerol, an endogenous cannabinoid receptor ligand, induces accelerated production of chemokines in HL-60 cells.

  Journal of biochemistry 20040401

• Anti-inflammatory and analgesic activity of Peperomia pellucida (L.) HBK (Piperaceae).

  Journal of ethnopharmacology 20040401

• Anti-inflammatory activity of methanolic extracts from Ventilago harmandiana Pierre.

  Journal of ethnopharmacology 20040401

• Maturation-related variations in prostaglandin and fatty acid content of ovary in the kuruma prawn (Marsupenaeus japonicus).

  Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20040401

• Polyunsaturated fatty acid levels in red cell membranes of unmedicated schizophrenic patients.

  The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 20040401

• Thiazolidinediones increase arachidonic acid release and subsequent prostanoid production in a peroxisome proliferator-activated receptor gamma-independent manner.

  Prostaglandins & other lipid mediators 20040401

• Type 1 diabetes compromises plasma arachidonic and docosahexaenoic acids in newborn babies.

  Lipids 20040401

• [Pharmacology and classification of cyclooxygenase inhibitors].

  Gastroenterologie clinique et biologique 20040401

• Thiol antioxidant and thiol-reducing agents attenuate 15-deoxy-delta 12,14-prostaglandin J2-induced heme oxygenase-1 expression.

  Life sciences 20040326

• Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin.

  Neuron 20040325

• [Mastopathy, breast cancer and iodolactone].

  Deutsche medizinische Wochenschrift (1946) 20040319

• Licofelone, an inhibitor of cyclooxygenase and 5-lipoxygenase, specifically inhibits cyclooxygenase-1-dependent platelet activation.

  European journal of pharmacology 20040319

• Ligand-dependent inhibition and reversal of tau filament formation.

  Biochemistry 20040316

• Non-toxic concentrations of peroxynitrite commit U937 cells to mitochondrial permeability transition-dependent necrosis that is however prevented by endogenous arachidonic acid.

  Biochemical pharmacology 20040315

• Rapid induction of apoptosis in prostate cancer cells by selenium: reversal by metabolites of arachidonate 5-lipoxygenase.

  Biochemical and biophysical research communications 20040312

• Cytosolic phospholipase A2-p11 interaction controls arachidonic acid release as a function of epithelial cell confluence.

  The Biochemical journal 20040301

• Catalytic activity and isoform-specific inhibition of rat cytochrome p450 4F enzymes.

  The Journal of pharmacology and experimental therapeutics 20040301

• The actin cytoskeleton facilitates complement-mediated activation of cytosolic phospholipase A2.

  American journal of physiology. Renal physiology 20040301

• Characterization of G proteins involved in activation of nonselective cation channels and arachidonic acid release by norepinephrine/alpha1A-adrenergic receptors.

  American journal of physiology. Cell physiology 20040301

• Relationship between lipoxygenase and human testicular cancer.

  International journal of molecular medicine 20040301

• Regulation of mouse renal CYP2J5 expression by sex hormones.

  Molecular pharmacology 20040301

• Colorado potato beetles show differential digestive compensatory responses to host plants expressing distinct sets of defense proteins.

  Archives of insect biochemistry and physiology 20040301

• Effect of dietary enrichment with n-3 polyunsaturated fatty acids (PUFA) or n-9 PUFA on arachidonate metabolism in vivo and experimentally induced inflammation in mice.

  Biological & pharmaceutical bulletin 20040301

• A novel role for phospholipase A2 isoforms in the checkpoint control of acute inflammation.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040301

• Rat brain arachidonic acid metabolism is increased by a 6-day intracerebral ventricular infusion of bacterial lipopolysaccharide.

  Journal of neurochemistry 20040301

• Angiogenic effect of prostaglandin I 2 in relation with its effect on PPAR nuclear receptors.

  Journal of molecular and cellular cardiology 20040301

• Methylmercury stimulates arachidonic acid release and cytosolic phospholipase A2 expression in primary neuronal cultures.

  Neurotoxicology 20040301

• Assessment of leukotriene B4 production in leukocytes from horses with recurrent airway obstruction.

  American journal of veterinary research 20040301

• Endothelium-dependent smooth muscle hyperpolarization: do gap junctions provide a unifying hypothesis?

  British journal of pharmacology 20040301

• Effect of dietary fat saturation on lipid metabolism, arachidonic acid turnover and peritoneal macrophage oxidative stress in mice.

  Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20040301

• Drug-induced airway diseases.

  Clinics in chest medicine 20040301

• [Influence of 2-aryl-3-halogen/3-hydroxy-1,4-naphthoquinones with salicylic and cinnamic acid partial structures on the arachidonic acid cascade].

  Die Pharmazie 20040301

• Effects of magnesium on prostacyclin synthesis and intracellular free calcium concentration in vascular cells.

  Magnesium research 20040301

• Upregulation of 8-lipoxygenase in the dermatitis of IkappaB-alpha-deficient mice.

  The Journal of investigative dermatology 20040301

• Evaluation of anti-platelet aggregatory effects of aspirin, cilostazol and ramatroban on platelet-rich plasma and whole blood.

  Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20040301

• Mechanisms of the influence of magnolol on eicosanoid metabolism in neutrophils.

  Biochemical pharmacology 20040301

• Ca2+ influx is not involved in acute cytotoxicity of arachidonic acid.

  Biochemical pharmacology 20040301

• Preventive effect of the flavonoid, wogonin, against ethanol-induced gastric mucosal damage in rats.

  Digestive diseases and sciences 20040301

• PI 3-kinase and MAP kinase regulate bradykinin induced prostaglandin E(2) release in human pulmonary artery by modulating COX-2 activity.

  FEBS letters 20040227

• [Physiopathology of severe sepsis].

  Presse medicale (Paris, France : 1983) 20040227

• [Intra-cellular signal pathway and synthesis of prostaglandin E2 during invasion of macrophage by Toxoplasma gondii].

  Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 20040227

• Cytochrome P450/NADPH-dependent formation of trans epoxides from trans-arachidonic acids.

  Bioorganic & medicinal chemistry letters 20040223

• Interleukin-1beta, transforming growth factor-beta1, and bradykinin attenuate cyclic AMP production by human pulmonary artery smooth muscle cells in response to prostacyclin analogues and prostaglandin E2 by cyclooxygenase-2 induction and downregulation of adenylyl cyclase isoforms 1, 2, and 4.

  Circulation research 20040220

• Evidence for an intermediate in tau filament formation.

  Biochemistry 20040217

• Presynaptic protein kinase C controls maturation and branch dynamics of developing retinotectal arbors: possible role in activity-driven sharpening.

  Journal of neurobiology 20040215

• Approaches to understanding the importance and clinical implications of peroxisome proliferator-activated receptor gamma (PPARgamma) signaling in prostate cancer.

  Journal of cellular biochemistry 20040215

• Calcium and its role in the nuclear translocation and activation of cytosolic phospholipase A2 in cells rendered sensitive to TNF-induced apoptosis by cycloheximide.

  Journal of immunology (Baltimore, Md. : 1950) 20040215

• Association of cystic fibrosis with abnormalities in fatty acid metabolism.

  The New England journal of medicine 20040205

• Fatty acid metabolism in cystic fibrosis.

  The New England journal of medicine 20040205

• PKC signaling mediates global enhancement of excitatory synaptogenesis in neurons triggered by local contact with astrocytes.

  Neuron 20040205

• Polymodal regulation of hTREK1 by pH, arachidonic acid, and hypoxia: physiological impact in acidosis and alkalosis.

  American journal of physiology. Cell physiology 20040201

• Arachidonic acid, palmitic acid and glucose are important for the modulation of clonal pancreatic beta-cell insulin secretion, growth and functional integrity.

  Clinical science (London, England : 1979) 20040201

• Arachidonic acid regulates two Ca2+ entry pathways via nitric oxide.

  Cellular signalling 20040201

• Prostaglandin synthases: recent developments and a novel hypothesis.

  Prostaglandins, leukotrienes, and essential fatty acids 20040201

• Topographical specialization of prostaglandin function in late pregnancy and at parturition in the baboon.

  Prostaglandins, leukotrienes, and essential fatty acids 20040201

• Apamin-sensitive K+ currents mediate arachidonic acid-induced relaxations of rabbit aorta.

  Hypertension (Dallas, Tex. : 1979) 20040201

• Nonsteroidal anti-inflammatory drugs and cyclooxygenase-2 selective inhibitors for prostate cancer chemoprevention.

  The Journal of urology 20040201

• Cyclic stretch-induced cPLA2 mediates ERK 1/2 signaling in rabbit proximal tubule cells.

  Kidney international 20040201

• Role of platelet microparticles in the production of thromboxane by rabbit pulmonary artery.

  Hypertension (Dallas, Tex. : 1979) 20040201

• A peroxisome proliferator-activated receptor-alpha activator induces renal CYP2C23 activity and protects from angiotensin II-induced renal injury.

  The American journal of pathology 20040201

• Histamine-induced inhibition of leukotriene biosynthesis in human neutrophils: involvement of the H2 receptor and cAMP.

  British journal of pharmacology 20040201

• The role of cytosolic phospholipase A(2) in insulin secretion.

  Diabetes 20040201

• Cyclooxygenase inhibition is associated with downregulation of apolipoprotein AI promoter activity in cultured hepatoma cell line HepG2.

  Metabolism: clinical and experimental 20040201

• CYP2E1 overexpression alters hepatocyte death from menadione and fatty acids by activation of ERK1/2 signaling.

  Hepatology (Baltimore, Md.) 20040201

• Prospective evaluation of the relationship between platelet-leukocyte conjugate formation and recurrent myocardial ischemia in patients with acute coronary syndromes.

  Platelets 20040201

• The influence of VIP and epoprostenol on platelet CD62P expression and primary haemostasis in vitro.

  Platelets 20040201

• The effects of TNF-alpha and inhibitors of arachidonic acid metabolism on human colon HT-29 cells depend on differentiation status.

  Differentiation; research in biological diversity 20040201

• Heme oxygenase-1 protects HepG2 cells against cytochrome P450 2E1-dependent toxicity.

  Free radical biology & medicine 20040201

• Downregulation of nitric oxide formation by cytosolic phospholipase A2-released arachidonic acid.

  Free radical biology & medicine 20040201

• Green tea polyphenol epigallocatechin-3-gallate protects HepG2 cells against CYP2E1-dependent toxicity.

  Free radical biology & medicine 20040201

• Regulation of arachidonic acid availability for eicosanoid production.

  Biochemistry and cell biology = Biochimie et biologie cellulaire 20040201

• In vitro nonenzymatic glycation enhances the role of myoglobin as a source of oxidative stress.

  Free radical research 20040201

• Lipopolysaccharide evokes microaggregation reactions in hemocytes isolated from tobacco hornworms, Manduca sexta.

  Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20040201

• Saturated fatty acids suppress adrenocorticotropic hormone (ACTH) release from rat anterior pituitary cells in vitro.

  Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20040201

• Cyclooxygenase-2 inhibitors: do they have a role in emergency department prescribing?

  Emergency medicine Australasia : EMA 20040201

• Isolation and characterization of delta(6)-desaturase, an ELO-like enzyme and delta(5)-desaturase from the liverwort Marchantia polymorpha and production of arachidonic and eicosapentaenoic acids in the methylotrophic yeast Pichia pastoris.

  Plant molecular biology 20040201

• Investigations into calcium-dependent membrane association of 15-lipoxygenase-1. Mechanistic roles of surface-exposed hydrophobic amino acids and calcium.

  The Journal of biological chemistry 20040130

• Identification of a novel class of endoperoxides from arachidonate autoxidation.

  The Journal of biological chemistry 20040130

• Requirement of protein kinase C micro activation and calpain-mediated proteolysis for arachidonic acid-stimulated adhesion of MDA-MB-435 human mammary carcinoma cells to collagen type IV.

  The Journal of biological chemistry 20040130

• Synthesis, biological properties, and molecular modeling investigations of novel 3,4-diarylpyrazolines as potent and selective CB(1) cannabinoid receptor antagonists.

  Journal of medicinal chemistry 20040129

• Inhibition of arachidonic acid release and cytosolic phospholipase A2 alpha activity by D-erythro-sphingosine.

  European journal of pharmacology 20040119

• Enzymatic synthesis of tea theaflavin derivatives and their anti-inflammatory and cytotoxic activities.

  Bioorganic & medicinal chemistry 20040115

• Involvement of p38 and p42/44 MAP kinases and protein kinase C in the interferon-gamma and interleukin-1alpha-induced phosphorylation of 85-kDa cytosolic phospholipase A(2) in primary human bronchial epithelial cells.

  Cytokine 20040107

• High omega-3 fatty acid content in alpine cheese: the basis for an alpine paradox.

  Circulation 20040106

• The caveolin scaffolding domain modifies 2-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor binding properties by inhibiting phospholipase A2 activity.

  The Journal of biological chemistry 20040102

• Role of cytosolic phospholipase A(2) in prostaglandin E(2) production by lung fibroblasts.

  American journal of respiratory cell and molecular biology 20040101

• Effects of dietary supplementation with arachidonic acid on platelet and renal function in patients with cirrhosis.

  Clinical science (London, England : 1979) 20040101

• Bcl-(xL) antagonism of BCR-coupled mitochondrial phospholipase A(2) signaling correlates with protection from apoptosis in WEHI-231 B cells.

  Blood 20040101

• Formula feeding potentiates docosahexaenoic and arachidonic acid biosynthesis in term and preterm baboon neonates.

  Journal of lipid research 20040101

• cPLA2 activator peptide, PLAP, increases arachidonic acid release and apoptosis of vascular smooth muscle cells.

  Journal of cellular physiology 20040101

• Adverse effect of obesity on red cell membrane arachidonic and docosahexaenoic acids in gestational diabetes.

  Diabetologia 20040101

• Recent advances in molecular biology and physiology of the prostaglandin E2-biosynthetic pathway.

  Progress in lipid research 20040101

• Epoxyeicosatrienoic acids (EETs): metabolism and biochemical function.

  Progress in lipid research 20040101

• Influence of interleukin-1alpha and COX-2 over the metabolism of arachidonic acid and glucose in isolated uterus of restricted diet rats.

  Prostaglandins, leukotrienes, and essential fatty acids 20040101

• Phosphatidyl choline fatty acid remodeling in the hepatic cell nuclei.

  Prostaglandins, leukotrienes, and essential fatty acids 20040101

• The synthesis and effects of prostaglandins on the ovary of the crab Oziotelphusa senex senex.

  General and comparative endocrinology 20040101

• PLA2 and secondary metabolites of arachidonic acid control filopodial behavior in neuronal growth cones.

  Cell motility and the cytoskeleton 20040101

• Arachidonic acid synthetic pathways of the oyster protozoan parasite, Perkinsus marinus: evidence for usage of a delta-8 pathway.

  Molecular and biochemical parasitology 20040101

• Activation of brain prostanoid EP3 receptors via arachidonic acid cascade during behavioral suppression induced by Delta8-tetrahydrocannabinol.

  Journal of neurochemistry 20040101

• Effects of different dietary oils on inflammatory mediator generation and fatty acid composition in rat neutrophils.

  Metabolism: clinical and experimental 20040101

• Absence of correlation between glycated hemoglobin and lipid composition of erythrocyte membrane in type 2 diabetic patients.

  Metabolism: clinical and experimental 20040101

• Effect of inhibitors of leukotriene and/or platelet activating factor on killed H. influenzae induced experimental otitis media with effusion.

  International journal of pediatric otorhinolaryngology 20040101

• A role for p38 MAP kinase in platelet activation by von Willebrand factor.

  Thrombosis and haemostasis 20040101

• The eicosanoid cascade: possible role in gliomas and meningiomas.

  Journal of clinical pathology 20040101

• The liver-selective nitric oxide donor O2-vinyl 1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate (V-PYRRO/NO) protects HepG2 cells against cytochrome P450 2E1-dependent toxicity.

  Molecular pharmacology 20040101

• Toxicity of glutathione depletion in mesencephalic cultures: a role for arachidonic acid and its lipoxygenase metabolites.

  The European journal of neuroscience 20040101

• Astrocytic regulation of NMDA receptor subunit composition modulates the toxicity of prion peptide PrP106-126.

  Molecular and cellular neurosciences 20040101

• [Benzo[c][2,7]naphthyridines from 2,6-dinor-nifedipine and its dimethyl 2,5-dicarboxylate isomer].

  Die Pharmazie 20040101

• Combination antiplatelet therapy in patients with peripheral vascular bypass grafts.

  Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20040101

• Helospectin I and II evoke vasodilation in the intact peripheral microcirculation.

  Peptides 20040101

• Effects of eicosanoid biosynthesis inhibitors on the prophenoloxidase-activating system and microaggregation reactions in the hemolymph of Rhodnius prolixus infected with Trypanosoma rangeli.

  Journal of insect physiology 20040101

• Histamine activates a background, arachidonic acid-sensitive K channel in embryonic chick dorsal root ganglion neurons.

  Neuroscience 20040101

• Eicosanoids: an emerging role in dendritic cell biology.

  Archivum immunologiae et therapiae experimentalis 20040101

• Clinical perspectives of anti-inflammatory therapy in the elderly: the lipoxigenase (LOX)/cycloxigenase (COX) inhibition concept.

  Archives of gerontology and geriatrics 20040101

• Regulation of recombinant human brain tandem P domain K+ channels by hypoxia: a role for O2 in the control of neuronal excitability?

  Journal of cellular and molecular medicine 20040101

• Diversity of TRP channel activation.

  Novartis Foundation symposium 20040101

• [Effect of systemic signaling molecules on the rate of spread of the immunizing effect of elicitors over potato tissues].

  Prikladnaia biokhimiia i mikrobiologiia 20040101

• Postsynaptic injection of calcium-independent phospholipase A2 inhibitors selectively increases AMPA receptor-mediated synaptic transmission.

  Hippocampus 20040101

• Metabolism of anandamide in cerebral microvascular endothelial cells.

  Prostaglandins & other lipid mediators 20040101

• Platelet function and its clinical significance in the myelodysplastic syndromes.

  The hematology journal : the official journal of the European Haematology Association 20040101

• Hydrolysis of nuclear phospholipids in relation with proliferative state in uterine stromal cells.

  Biochimie 20040101

• In vitro proliferation of fibrosarcoma cells depends on intact functions of lipoxygenases and cytochrome P-450-monooxygenase.

  Cancer investigation 20040101

• Role of COX-2 inhibitors in cancer therapy.

  Cancer investigation 20040101

• Inhibition of hemocyte microaggregation reactions in Rhodnius prolixus larvae orally infected with Trypanosoma rangeli.

  Experimental parasitology 20040101

• Measurement of platelet arachidonic acid metabolism.

  Methods in molecular biology (Clifton, N.J.) 20040101

• Maternal DHA and the development of attention in infancy and toddlerhood.

  Child development 20040101

• PHGPx overexpression induces an increase in COX-2 activity in colon carcinoma cells.

  Anticancer research 20040101

• Proteasome inhibitors: their effects on arachidonic acid release from cells in culture and arachidonic acid metabolism in rat liver cells.

  BMC pharmacology 20040101

• Protective role of Phaseolus vulgaris on changes in the fatty acid composition in experimental diabetes.

  Journal of medicinal food 20040101

• Regulation and role of arachidonate cascade during changes in life cycle of adipocytes.

  Applied biochemistry and biotechnology 20040101

• Tamoxifen and the Rafoxifene analog LY117018: their effects on arachidonic acid release from cells in culture and on prostaglandin I2 production by rat liver cells.

  BMC cancer 20040101

• Biological nitration of arachidonic acid.

  Current vascular pharmacology 20040101

• [The influence of nitric oxide generation on the production of interleukins and processes of prostaglandin synthesis in fetal membranes in spontaneous parturition and uterine inertia].

  Biomeditsinskaia khimiia 20040101

• Isolating Mortierella alpina strains of high yield of arachidonic acid.

  Letters in applied microbiology 20040101

• Aspirin-induced asthma: clinical aspects, pathogenesis and management.

  Drugs 20040101

• Decrease of human hepatoma cell growth by arachidonic acid is associated with an accumulation of derived products from lipid peroxidation.

  Biochimie 20040101

• Omega-3 fatty acids and selenium as coronary heart disease risk modifying factors in Asian Indian and Chinese males.

  Nutrition (Burbank, Los Angeles County, Calif.) 20040101

• [Fluorescent-labeled lipophilic analogues of serotonin, dopamine, and acetylcholine: synthesis, mass spectrometry, and biological activity].

  Bioorganicheskaia khimiia 20040101

• Immobilization of Candida bombicola cells on free-standing organic-gold nanoparticle membranes and their use as enzyme sources in biotransformations.

  Biotechnology progress 20040101

• Combination treatment using the COX-2 inhibitor meloxicam and an anti-allergic in pollinosis.

  The Journal of international medical research 20040101

• Stimulus-secretion coupling in the pancreatic beta-cell.

  Advances in experimental medicine and biology 20040101

• Inhibitory activity of shiitake flavor against platelet aggregation.

  BioFactors (Oxford, England) 20040101

• Production and stability of structured lipids from algal oils and capric acid.

  BioFactors (Oxford, England) 20040101

• Regulation of capacitative and non-capacitative Ca2+ entry in A7r5 vascular smooth muscle cells.

  Biological research 20040101

• Polyunsaturated fatty acids in the central nervous system: evolution of concepts and nutritional implications throughout life.

  Reproduction, nutrition, development 20040101

• Analysis of responses to St. John's Wort in the feline pulmonary vascular bed.

  Journal of herbal pharmacotherapy 20040101

• DNA damage and mutations induced by arachidonic acid peroxidation.

  Biochemistry 20031230

• Effects of lipid-esterified conjugated linoleic acid isomers on platelet function: evidence for stimulation of platelet phospholipase activity.

  Biochimica et biophysica acta 20031230

• Release of arachidonic acid by stimulation of opsonic receptors in human monocytes: the FcgammaR and the complement receptor 3 pathways.

  The Journal of biological chemistry 20031226

• A key role for TRPM7 channels in anoxic neuronal death.

  Cell 20031226

• Cytochrome P450: major player in reperfusion injury.

  Archives of biochemistry and biophysics 20031215

• Inflammatory effects of snake venom myotoxic phospholipases A2.

  Toxicon : official journal of the International Society on Toxinology 20031215

• Cyclooxygenase-2 induction by bradykinin in human pulmonary artery smooth muscle cells is mediated by the cyclic AMP response element through a novel autocrine loop involving endogenous prostaglandin E2, E-prostanoid 2 (EP2), and EP4 receptors.

  The Journal of biological chemistry 20031212

• 12-lipoxygenase metabolites of arachidonic acid mediate metabotropic glutamate receptor-dependent long-term depression at hippocampal CA3-CA1 synapses.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20031210

• Pyrazole and isoxazole derivatives as new, potent, and selective 20-hydroxy-5,8,11,14-eicosatetraenoic acid synthase inhibitors.

  Journal of medicinal chemistry 20031204

• Role of secretory and cytosolic phospholipase A(2) enzymes in lysophosphatidylcholine-stimulated monocyte arachidonic acid release.

  FEBS letters 20031204

• Arachidonic acid-activated Na+-dependent Mg2+ efflux in rat renal epithelial cells.

  Biochimica et biophysica acta 20031203

• Pancreatic islets and insulinoma cells express a novel isoform of group VIA phospholipase A2 (iPLA2 beta) that participates in glucose-stimulated insulin secretion and is not produced by alternate splicing of the iPLA2 beta transcript.

  Biochemistry 20031202

• Reactive oxygen species mediate arachidonic acid-induced dilation in porcine coronary microvessels.

  American journal of physiology. Heart and circulatory physiology 20031201

• 11,12,15-Trihydroxyeicosatrienoic acid mediates ACh-induced relaxations in rabbit aorta.

  American journal of physiology. Heart and circulatory physiology 20031201

• Arachidonic acid-dependent inhibition of adipocyte differentiation requires PKA activity and is associated with sustained expression of cyclooxygenases.

  Journal of lipid research 20031201

• Control of endothelial cell proliferation by calcium influx and arachidonic acid metabolism: a pharmacological approach.

  Journal of cellular physiology 20031201

• Sensitization of adenylate cyclase by short-term activation of 5-HT1A receptors.

  Cellular signalling 20031201

• Role of COX-1 and -2 in prostanoid generation and modulation of angiotensin II responses.

  American journal of physiology. Heart and circulatory physiology 20031201

• From membrane phospholipid defects to altered neurotransmission: is arachidonic acid a nexus in the pathophysiology of schizophrenia?

  Prostaglandins, leukotrienes, and essential fatty acids 20031201

• Relationship between the niacin skin flush response and essential fatty acids in schizophrenia.

  Prostaglandins, leukotrienes, and essential fatty acids 20031201

• Apolipoprotein D modulates arachidonic acid signaling in cultured cells: implications for psychiatric disorders.

  Prostaglandins, leukotrienes, and essential fatty acids 20031201

• Prostaglandin E2 production in astrocytes: regulation by cytokines, extracellular ATP, and oxidative agents.

  Prostaglandins, leukotrienes, and essential fatty acids 20031201

• Omega-3 and omega-6 fatty acid concentrations in red blood cell membranes relate to schizotypal traits in healthy adults.

  Prostaglandins, leukotrienes, and essential fatty acids 20031201

• Evidence that macrophages transfer arachidonic acid and cholesterol to tissues in vivo.

  Cell biochemistry and function 20031201

• Increased acute inflammation, leukotriene B4-induced chemotaxis, and signaling in mice deficient for G protein-coupled receptor kinase 6.

  Journal of immunology (Baltimore, Md. : 1950) 20031201

• Formula supplementation and growth.

  Pediatrics 20031201

• Isolevuglandins, a novel class of isoprostenoid derivatives, function as integrated sensors of oxidant stress and are generated by myeloperoxidase in vivo.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20031201

• Effect of pentoxifylline on arachidonic acid metabolism, neutral lipid synthesis and accumulation during induction of the lipocyte phenotype by retinol in murine hepatic stellate cell.

  Molecular and cellular biochemistry 20031201

• Targeting cyclooxygenase-2 in human neoplasia: rationale and promise.

  Cancer cell 20031201

• Analysis of responses to valerian root extract in the feline pulmonary vascular bed.

  Journal of alternative and complementary medicine (New York, N.Y.) 20031201

• Auditory brainstem evoked response in juvenile rats fed rat milk formulas with high docosahexaenoic acid.

  Nutritional neuroscience 20031201

• Determination of fatty acid levels in erythrocyte membranes of patients with chronic fatigue syndrome.

  Nutritional neuroscience 20031201

• Metabolic changes of arachidonic acid after cerebral ischemia-reperfusion in diabetic rats.

  Experimental neurology 20031201

• Regiospecific analysis by ethanolysis of oil with immobilized Candida antarctica lipase.

  Lipids 20031201

• Noradrenaline-induced contraction mediated by endothelial COX-1 metabolites in the rat coronary artery.

  Journal of cardiovascular pharmacology 20031201

• Localization of group V phospholipase A2 in caveolin-enriched granules in activated P388D1 macrophage-like cells.

  The Journal of biological chemistry 20031128

• Arachidonic acid peroxides induce apoptotic Neuro-2A cell death in association with intracellular Ca(2+) rise and mitochondrial damage independently of caspase-3 activation.

  Brain research 20031121

• Differential modulation of glucocorticoid action by FK506 in A549 cells.

  The Biochemical journal 20031115

• In vivo identification of aflatoxin-induced free radicals in rat bile.

  Free radical biology & medicine 20031115

• A novel mechanism of cyclooxygenase-2 inhibition involving interactions with Ser-530 and Tyr-385.

  The Journal of biological chemistry 20031114

• Pharmacological characterization of lysophospholipid receptor signal transduction pathways in rat cerebrocortical astrocytes.

  Brain research 20031114

• Bromoenol lactone promotes cell death by a mechanism involving phosphatidate phosphohydrolase-1 rather than calcium-independent phospholipase A2.

  The Journal of biological chemistry 20031107

• Signal transduction pathways involved in proteolysis-inducing factor induced proteasome expression in murine myotubes.

  British journal of cancer 20031103

• Nitric oxide-epoxygenase interactions and arachidonate-induced dilation of rat renal microvessels.

  American journal of physiology. Heart and circulatory physiology 20031101

• Arachidonic acid metabolites contribute to the irreversible depolarization induced by in vitro ischemia.

  Journal of neurophysiology 20031101

• Effects of valeryl salicylate, a COX-1 inhibitor, on models of acute inflammation in mice.

  Pharmacological research 20031101

• Novel chemoattractant peptides for human leukocytes.

  Biochemical pharmacology 20031101

• Thiamylal and pentobarbital have opposite effects on human platelet aggregation in vitro.

  Anesthesia and analgesia 20031101

• Arachidonic acid cascade inhibitors modulate phorbol ester-induced oxidative stress in female ICR mouse skin: differential roles of 5-lipoxygenase and cyclooxygenase-2 in leukocyte infiltration and activation.

  Free radical biology & medicine 20031101

• Effect of olive oil minor components on oxidative stress and arachidonic acid mobilization and metabolism by macrophages RAW 264.7.

  Free radical biology & medicine 20031101

• beta2-Adrenergic signaling in human heart: shift from the cyclic AMP to the arachidonic acid pathway.

  Molecular pharmacology 20031101

• Arachidonic acid triggers an oxidative burst in leukocytes.

  Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20031101

• Adenovirus-mediated expression of Cu/Zn- or Mn-superoxide dismutase protects against CYP2E1-dependent toxicity.

  Hepatology (Baltimore, Md.) 20031101

• Augmented PLA2 activity in pre-eclamptic decidual tissue--a key player in the pathophysiology of 'acute atherosis' in pre-eclampsia?

  Placenta 20031101

• Mechanisms of the priming effect of low doses of lipopoly-saccharides on leukocyte-dependent platelet aggregation in whole blood.

  Thrombosis and haemostasis 20031101

• Spatial and temporal variation of the fatty acid composition of Patella spp. (Gastropoda: Prosobranchia) soft bodies and gonads.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20031101

• Arachidonic acid and colorectal carcinogenesis.

  Molecular and cellular biochemistry 20031101

• Diversity of endothelium-derived vasocontracting factors--arachidonic acid metabolites.

  Acta pharmacologica Sinica 20031101

• Beneficial effects of a diet rich in a mixture of n - 6/n - 3 essential fatty acids and of their metabolites on cyclosporine - nephrotoxicity.

  The Journal of nutritional biochemistry 20031101

• Renal development in high-glucose ambience and diabetic embryopathy.

  Seminars in nephrology 20031101

• H2O2-induced platelet aggregation and increase in intracellular Ca2+ concentration are blocked by inhibitors of intracellular signaling.

  Biochemistry. Biokhimiia 20031101

• Regulation of selenoprotein GPx4 expression and activity in human endothelial cells by fatty acids, cytokines and antioxidants.

  Atherosclerosis 20031101

• Apoptosis of spinal cord neurons by preventing depletion nicotine attenuates arachidonic acid-induced of neurotrophic factors.

  Journal of neurotrauma 20031101

• Conjugated linoleic acid (CLA)-enriched milk fat inhibits growth and modulates CLA-responsive biomarkers in MCF-7 and SW480 human cancer cell lines.

  The British journal of nutrition 20031101

• Dietary conjugated linoleic acid differentially alters fatty acid composition and increases conjugated linoleic acid content in porcine adipose tissue.

  The British journal of nutrition 20031101

• Infant intake of fatty acids from human milk over the first year of lactation.

  The British journal of nutrition 20031101

• Corticosteroid effect on Caco-2 cell lipids depends on cell differentiation.

  The Journal of steroid biochemistry and molecular biology 20031101

• The antiplatelet activity of Danggijakyaksan by inhibition of phospholipase C.

  Immunopharmacology and immunotoxicology 20031101

• The predominance of omega-6 polyunsaturated fatty acids in cystic fibrosis despite low arachidonic acid levels.

  Acta paediatrica (Oslo, Norway : 1992) 20031101

• Genes regulated by arachidonic and oleic acids in Raji cells.

  Lipids 20031101

• Anti-inflammatory compounds of plant origin. Part I. Action on arachidonic acid pathway, nitric oxide and nuclear factor kappa B (NF-kappaB).

  Planta medica 20031101

• A requirement for calcium-independent phospholipase A2 in thrombin-induced arachidonic acid release and growth in vascular smooth muscle cells.

  The Journal of biological chemistry 20031031

• A diacylglycerol-gated cation channel in vomeronasal neuron dendrites is impaired in TRPC2 mutant mice: mechanism of pheromone transduction.

  Neuron 20031030

• Pyridoxamine traps intermediates in lipid peroxidation reactions in vivo: evidence on the role of lipids in chemical modification of protein and development of diabetic complications.

  The Journal of biological chemistry 20031024

• Effect of arachidonic acid on proliferation, cytokines production and pleiotropic genes expression in Jurkat cells--a comparison with oleic acid.

  Life sciences 20031024

• Group III secreted phospholipase A2 causes apoptosis in rat primary cortical neuronal cultures.

  Brain research 20031024

• Mechanism of group IVA cytosolic phospholipase A(2) activation by phosphorylation.

  The Journal of biological chemistry 20031017

• Secretory phospholipase A2 is released from pancreatic beta-cells and stimulates insulin secretion via inhibition of ATP-dependent K+ channels.

  Biochemical and biophysical research communications 20031017

• Activation of group IV cytosolic phospholipase A2 in human eosinophils by phosphoinositide 3-kinase through a mitogen-activated protein kinase-independent pathway.

  Journal of immunology (Baltimore, Md. : 1950) 20031015

• Advanced glycation end products stimulate an enhanced neutrophil respiratory burst mediated through the activation of cytosolic phospholipase A2 and generation of arachidonic Acid.

  Circulation 20031014

• Fusion of lamellar body with plasma membrane is driven by the dual action of annexin II tetramer and arachidonic acid.

  The Journal of biological chemistry 20031010

• Inhibition by arachidonic acid and other fatty acids of dopamine uptake at the human dopamine transporter.

  European journal of pharmacology 20031008

• Arachidonylsulfonyl derivatives as cannabinoid CB1 receptor and fatty acid amide hydrolase inhibitors.

  Bioorganic & medicinal chemistry letters 20031006

• Human group V phospholipase A2 induces group IVA phospholipase A2-independent cysteinyl leukotriene synthesis in human eosinophils.

  The Journal of biological chemistry 20031003

• Ceramide kinase mediates cytokine- and calcium ionophore-induced arachidonic acid release.

  The Journal of biological chemistry 20031003

• Arachidonic acid activation of translation initiation signaling in vascular smooth muscle cells.

  Biochemical and biophysical research communications 20031003

• Free fatty acids in cerebrospinal fluids from patients with traumatic brain injury.

  Neuroscience letters 20031002

• p38 mitogen-activated protein kinase protects glomerular epithelial cells from complement-mediated cell injury.

  American journal of physiology. Renal physiology 20031001

• Effects of dietary n-3 or n-6 fatty acids on interleukin-1beta-induced anxiety, stress, and inflammatory responses in rats.

  Journal of lipid research 20031001

• Inhibitors of 20-HETE formation promote salt-sensitive hypertension in rats.

  Hypertension (Dallas, Tex. : 1979) 20031001

• PPARgamma ligands induce prostaglandin production in vascular smooth muscle cells: indomethacin acts as a peroxisome proliferator-activated receptor-gamma antagonist.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20031001

• Role of COX-2 in the enhanced vasoconstrictor effect of arachidonic acid in the diabetic rat kidney.

  Hypertension (Dallas, Tex. : 1979) 20031001

• 5,6-epoxyeicosatrienoic acid mediates the enhanced renal vasodilation to arachidonic acid in the SHR.

  Hypertension (Dallas, Tex. : 1979) 20031001

• Downregulation of renal CYP-derived eicosanoid synthesis in rats with diet-induced hypertension.

  Hypertension (Dallas, Tex. : 1979) 20031001

• Interleukin-13 upregulates vasodilatory 15-lipoxygenase eicosanoids in rabbit aorta.

  Arteriosclerosis, thrombosis, and vascular biology 20031001

• 14,15-epoxyeicosa-5(Z)-enoic-mSI: a 14,15- and 5,6-EET antagonist in bovine coronary arteries.

  Hypertension (Dallas, Tex. : 1979) 20031001

• Dietary conjugated linoleic acid reduces PGE2 release and interstitial injury in rat polycystic kidney disease.

  Kidney international 20031001

• Effect of three triterpenoid compounds isolated from root bark of Aralia elata on stimulus-induced superoxide generation and tyrosyl phosphorylation and translocation of p47(phox) and p67(phox) to cell membrane in human neutrophil.

  Clinica chimica acta; international journal of clinical chemistry 20031001

• Calcium entry and the control of calcium oscillations.

  Biochemical Society transactions 20031001

• Effects of wogonin, a plant flavone from Scutellaria radix, on skin inflammation: in vivo regulation of inflammation-associated gene expression.

  Biochemical pharmacology 20031001

• Decreased prostatic arachidonic acid in human prostatic carcinoma.

  BJU international 20031001

• Possible role of arachidonic acid in the regulation of lactate production in rat Sertoli cells.

  International journal of andrology 20031001

• Evaluation of the contribution of cyclooxygenase 1 and cyclooxygenase 2 to the production of PGE2 and PGF2 alpha in epithelial cells from bovine endometrium.

  Reproduction (Cambridge, England) 20031001

• Differential incorporation of docosahexaenoic and arachidonic acids by the yolk sac membrane of the avian embryo.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20031001

• Synergism interaction between arachidonic acid by 5-hydroxytryptamine in human platelet aggregation is mediated through multiple signalling pathways.

  Acta pharmacologica Sinica 20031001

• Astrocyte-mediated methylmercury neurotoxicity.

  Biological trace element research 20031001

• Long chain polyunsaturate supplementation does not induce excess lipid peroxidation of piglet tissues.

  European journal of nutrition 20031001

• Phospholipase A2, hydroxyl radicals, and lipid peroxidation in transient cerebral ischemia.

  Antioxidants & redox signaling 20031001

• Perinatal biochemistry and physiology of long-chain polyunsaturated fatty acids.

  The Journal of pediatrics 20031001

• Term infant studies of DHA and ARA supplementation on neurodevelopment: results of randomized controlled trials.

  The Journal of pediatrics 20031001

• In vivo approaches to quantifying and imaging brain arachidonic and docosahexaenoic acid metabolism.

  The Journal of pediatrics 20031001

• Single oral dose study of two isosorbide-based aspirin prodrugs in the dog.

  The Journal of pharmacy and pharmacology 20031001

• Fatty acid profile of oesophageal mucosa in children with gastro-oesophageal reflux disease.

  Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20031001

• Role of cytochrome P450-dependent arachidonic acid metabolites in liver physiology and pathophysiology.

  Prostaglandins & other lipid mediators 20031001

• Effect of dietary fat level and sesamin on the polyunsaturated fatty acid metabolism in rats.

  Journal of nutritional science and vitaminology 20031001

• Plasma fatty acid composition and incidence of coronary heart disease in middle aged adults: the Atherosclerosis Risk in Communities (ARIC) Study.

  Nutrition, metabolism, and cardiovascular diseases : NMCD 20031001

• Indomethacin reverts sleep disorders produced by ozone exposure in rats.

  Toxicology 20030930

• Arachidonic acid regulates surface expression of epithelial sodium channels.

  The Journal of biological chemistry 20030919

• Activation of p38 mitogen-activated protein kinase/cytosolic phospholipase A2 cascade in hydroperoxide-stressed platelets.

  Free radical biology & medicine 20030915

• Arachidonic acid activates a functional AP-1 and an inactive NF-kappaB complex in human HepG2 hepatoma cells.

  Free radical biology & medicine 20030915

• Role of cyclooxygenase-2, but not cyclooxygenase-1, on type II collagen-induced arthritis in DBA/1J mice.

  Biochemical pharmacology 20030915

• Molecular identification of a functional homologue of the mammalian fatty acid amide hydrolase in Arabidopsis thaliana.

  The Journal of biological chemistry 20030912

• Acyl carriers used as substrates by the desaturases and elongases involved in very long-chain polyunsaturated fatty acids biosynthesis reconstituted in yeast.

  The Journal of biological chemistry 20030912

• Role of phospholipase A2 activation and calcium in CYP2E1-dependent toxicity in HepG2 cells.

  The Journal of biological chemistry 20030905

• Dietary alpha-linolenic acid suppresses the formation of lysophosphatidic acid, a lipid mediator, in rat platelets compared with linoleic acid.

  Life sciences 20030905

• The receptor RAGE as a progression factor amplifying arachidonate-dependent inflammatory and proteolytic response in human atherosclerotic plaques: role of glycemic control.

  Circulation 20030902

• Polyunsaturated fatty acids and bovine interferon-tau modify phorbol ester-induced secretion of prostaglandin F2 alpha and expression of prostaglandin endoperoxide synthase-2 and phospholipase-A2 in bovine endometrial cells.

  Biology of reproduction 20030901

• Distinct regulation of cytosolic phospholipase A2 phosphorylation, translocation, proteolysis and activation by tumour necrosis factor-receptor subtypes.

  The Biochemical journal 20030901

• The deregulation of arachidonic acid metabolism-related genes in human esophageal squamous cell carcinoma.

  International journal of cancer 20030901

• The isoprostanes: unique products of arachidonic acid oxidation-a review.

  Current medicinal chemistry 20030901

• Characterization of Ca2+ channels and G proteins involved in arachidonic acid release by endothelin-1/endothelinA receptor.

  Molecular pharmacology 20030901

• Arachidonic acid in mononuclear cells and its clinical significance in HCV cirrhotic patients.

  Nutrition (Burbank, Los Angeles County, Calif.) 20030901

• Experimental and interventional dietary study in humans on the role of HDL fatty acid composition in PGI2 release and Cox-2 expression by VSMC.

  European journal of clinical investigation 20030901

• Unique effect of arachidonic acid on human neutrophil TNF receptor expression: up-regulation involving protein kinase C, extracellular signal-regulated kinase, and phospholipase A2.

  Journal of immunology (Baltimore, Md. : 1950) 20030901

• Inhibition of C6 glioma cell proliferation by anandamide, 1-arachidonoylglycerol, and by a water soluble phosphate ester of anandamide: variability in response and involvement of arachidonic acid.

  Biochemical pharmacology 20030901

• Phospholipase C and phosphatidylinositol 3-kinase signaling are involved in the exogenous arachidonic acid-stimulated respiratory burst in human neutrophils.

  Journal of leukocyte biology 20030901

• Visual, cognitive, and language assessments at 39 months: a follow-up study of children fed formulas containing long-chain polyunsaturated fatty acids to 1 year of age.

  Pediatrics 20030901

• Role of mitogen-activated protein kinases in influenza virus induction of prostaglandin E2 from arachidonic acid in bronchial epithelial cells.

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20030901

• Depletion of phospholipid hydroperoxide glutathione peroxidase up-regulates arachidonate metabolism by 12S-lipoxygenase and cyclooxygenase 1 in human epidermoid carcinoma A431 cells.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030901

• Relationship of arachidonic acid concentration to cyclooxygenase-dependent human platelet aggregation.

  Journal of clinical pharmacology 20030901

• Effect of polyunsaturated fatty acids on the expression of transcription factor adipocyte determination and differentiation-dependent factor 1 and of lipogenic and fatty acid oxidation enzymes in porcine differentiating adipocytes.

  The British journal of nutrition 20030901

• Platelet anti-aggregatory effects of coumarins from the roots of Angelica genuflexa and A. gigas.

  Archives of pharmacal research 20030901

• Host defense against bacterial keratitis.

  Ocular immunology and inflammation 20030901

• Platelet function tests using platelet aggregometry: need for repetition of the test for diagnosis of defective platelet function.

  Platelets 20030901

• Effects of arachidonic acid on leptin secretion and expression in primary cultured rat adipocytes.

  Journal of physiology and biochemistry 20030901

• Polyunsaturated fatty acid status and relapse vulnerability in cocaine addicts.

  Psychiatry research 20030830

• Modulation of D-penicillamine-induced autoimmunity in the Brown Norway rat using pharmacological agents that interfere with arachidonic acid metabolism or synthesis of inducible nitric oxide synthase.

  Toxicology 20030828

• Dietary fatty acids and immune reactions in synovial tissue.

  European journal of medical research 20030820

• Role of cyclooxygenase-2 in the generation of vasoactive prostanoids in the rat pulmonary and systemic vascular beds.

  Circulation 20030819

• Antiplatelet activity of benzylisoquinoline derivatives oxidized by cerium(IV) ammonium nitrate.

  Bioorganic & medicinal chemistry letters 20030818

• Thiyl radicals in biosystems: inhibition of the prostaglandin metabolism by the cis-trans-isomerization of arachidonic acid double bonds.

  Archives of biochemistry and biophysics 20030815

• 2,4-Decadienals are produced via (R)-11-HPITE from arachidonic acid in marine green alga Ulva conglobata.

  Bioorganic & medicinal chemistry 20030815

• Capsaicin-like effects of N-arachidonoyl-dopamine in the isolated guinea pig bronchi and urinary bladder.

  European journal of pharmacology 20030815

• p38 MAP kinase mediates both short-term and long-term synaptic depression in aplysia.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20030813

• Functional and biochemical evaluation of platelet aspirin resistance after coronary artery bypass surgery.

  Circulation 20030805

• Effect of catechol derivatives on cell growth and lipoxygenase activity.

  Bioorganic & medicinal chemistry letters 20030804

• Involvement of extracellular Ca2+ influx and epidermal growth factor receptor tyrosine kinase transactivation in endothelin-1-induced arachidonic acid release.

  British journal of pharmacology 20030802

• The influence of prematurity and long chain polyunsaturate supplementation in 4-week adjusted age baboon neonate brain and related tissues.

  Pediatric research 20030801

• Formation of prostaglandins E2 and D2 via the isoprostane pathway: a mechanism for the generation of bioactive prostaglandins independent of cyclooxygenase.

  The Journal of biological chemistry 20030801

• Nox4 mediates angiotensin II-induced activation of Akt/protein kinase B in mesangial cells.

  American journal of physiology. Renal physiology 20030801

• Obesity is associated with impaired platelet-inhibitory effect of acetylsalicylic acid in nondiabetic subjects.

  International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 20030801

• 17Beta-eEstradiol stimulates arachidonate release from human amnion-like WISH cells through a rapid mechanism involving a membrane receptor.

  Endocrinology 20030801

• Is survival possible without arachidonate metabolites in the brain during systemic infection?

  News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society 20030801

• Differential involvement of intracellular domains of the rat NTS1 neurotensin receptor in coupling to G proteins: a molecular basis for agonist-directed trafficking of receptor stimulus.

  Molecular pharmacology 20030801

• Synaptic plasticity preserved with arachidonic acid diet in aged rats.

  Neuroscience research 20030801

• A complex signaling cascade links the serotonin2A receptor to phospholipase A2 activation: the involvement of MAP kinases.

  Journal of neurochemistry 20030801

• The role of PAR4 in thrombin-induced thromboxane production in human platelets.

  Thrombosis and haemostasis 20030801

• Enhanced TNF alpha and oxidative stress in patients with heart failure: effect of TNF alpha on platelet O2- production.

  Thrombosis and haemostasis 20030801

• Blockade of LTC4 synthesis caused by additive inhibition of gIV-PLA2 phosphorylation: Effect of salmeterol and PDE4 inhibition in human eosinophils.

  The Journal of allergy and clinical immunology 20030801

• Decreased lysophosphatidylcholine/phosphatidylcholine ratio in cerebrospinal fluid in Alzheimer's disease.

  Journal of neural transmission (Vienna, Austria : 1996) 20030801

• Celecoxib reduces skin damage after radiation: selective reduction of chemokine and receptor mRNA expression in irradiated skin but not in irradiated mammary tumor.

  American journal of clinical oncology 20030801

• TRA-418, a novel compound having both thromboxane A(2) receptor antagonistic and prostaglandin I(2) receptor agonistic activities: its antiplatelet effects in human and animal platelets.

  Journal of thrombosis and haemostasis : JTH 20030801

• Imaging of brain serotonergic neurotransmission involving phospholipase A2 activation and arachidonic acid release in unanesthetized rats.

  Brain research. Brain research protocols 20030801

• Fatty acid composition and productive traits of broiler fed diets containing conjugated linoleic acid.

  Poultry science 20030801

• Antioxidant effect of conjugated linoleic acid and vitamin A during non enzymatic lipid peroxidation of rat liver microsomes and mitochondria.

  Molecular and cellular biochemistry 20030801

• Time related changes in calcium handling in the isolated ischemic and reperfused rat heart.

  Molecular and cellular biochemistry 20030801

• Inhibition of alpha, betaI, delta, eta, and zeta protein kinase C isoforms by xanthonolignoids.

  Journal of enzyme inhibition and medicinal chemistry 20030801

• The role of inflammatory mediators in severe acute pancreatitis and regulation of glucocorticoids.

  Hepatobiliary & pancreatic diseases international : HBPD INT 20030801

• An unusual isotope effect on substrate inhibition in the oxidation of arachidonic acid by lipoxygenase.

  Journal of the American Chemical Society 20030730

• Amelioration of tacrolimus-induced nephrotoxicity in rats using juniper oil.

  Transplantation 20030727

• A novel two-pore domain K+ channel, TRESK, is localized in the spinal cord.

  The Journal of biological chemistry 20030725

• Ca2+-independent phospholipases A2 and production of arachidonic acid in nuclei of LA-N-1 cell cultures: a specific receptor activation mediated with retinoic acid.

  Brain research. Molecular brain research 20030723

• Coupling between cyclooxygenases and prostaglandin F(2alpha) synthase. Detection of an inducible, glutathione-activated, membrane-bound prostaglandin F(2alpha)-synthetic activity.

  Biochimica et biophysica acta 20030721

• Amplification mechanisms of inflammation: paracrine stimulation of arachidonic acid mobilization by secreted phospholipase A2 is regulated by cytosolic phospholipase A2-derived hydroperoxyeicosatetraenoic acid.

  Journal of immunology (Baltimore, Md. : 1950) 20030715

• Mechanisms of enhanced apoptosis in HL-60 cells by UV-irradiated n-3 and n-6 polyunsaturated fatty acids.

  Free radical biology & medicine 20030715

• Changing the conformation state of cytochrome b558 initiates NADPH oxidase activation: MRP8/MRP14 regulation.

  The Journal of biological chemistry 20030711

• Anionic micelles and vesicles induce tau fibrillization in vitro.

  The Journal of biological chemistry 20030711

• Osteoblast-derived oxysterol is a migration-inducing factor for human breast cancer cells.

  The Journal of biological chemistry 20030711

• PGE(2) is generated by specific COX-2 activity and increases VEGF production in COX-2-expressing human pancreatic cancer cells.

  Biochemical and biophysical research communications 20030711

• Identification of hepatic peroxisomal phospholipase A(2) and characterization of arachidonic acid-containing choline glycerophospholipids in hepatic peroxisomes.

  FEBS letters 20030710

• Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor Mas.

  Proceedings of the National Academy of Sciences of the United States of America 20030708

• Supplementation with fish oil affects the association between very long-chain n-3 polyunsaturated fatty acids in serum non-esterified fatty acids and soluble vascular cell adhesion molecule-1.

  Clinical science (London, England : 1979) 20030701

• Improved arachidonic acids production from the fungus Mortierella alpina by glutamate supplementation.

  Bioresource technology 20030701

• 17beta-estradiol decreases vascular tone in cerebral arteries by shifting COX-dependent vasoconstriction to vasodilation.

  American journal of physiology. Heart and circulatory physiology 20030701

• cPLA2alpha-evoked formation of arachidonic acid and lysophospholipids is required for exocytosis in mouse pancreatic beta-cells.

  American journal of physiology. Endocrinology and metabolism 20030701

• Do angiotensin-converting enzyme inhibitors directly stimulate the kinin B1 receptor?

  American journal of physiology. Heart and circulatory physiology 20030701

• Properties of phagocyte NADPH oxidase p47-phox mutants with unmasked SH3 (Src homology 3) domains: full reconstitution of oxidase activity in a semi-recombinant cell-free system lacking arachidonic acid.

  The Biochemical journal 20030701

• Phospholipase A(2) isoforms: a perspective.

  Cellular signalling 20030701

• Cdc42 and RhoA are differentially regulated during arachidonate-mediated HeLa cell adhesion.

  Journal of cellular physiology 20030701

• Deletion of cytosolic phospholipase A2 promotes striated muscle growth.

  Nature medicine 20030701

• The antiplatelet activity of Geiji-Bokryung-Hwan, Korean traditional formulation, is mediated through inhibition of phospholipase C and inhibition of TxB(2) synthetase activity.

  International immunopharmacology 20030701

• Increased epoxyeicosatrienoic acid formation in the rat kidney during liver cirrhosis.

  Journal of the American Society of Nephrology : JASN 20030701

• Moderate alcohol consumption increases oxidative stress in patients with chronic hepatitis C.

  Hepatology (Baltimore, Md.) 20030701

• Docosahexaenoic acid and arachidonic acid release in rat brain astrocytes is mediated by two separate isoforms of phospholipase A2 and is differently regulated by cyclic AMP and Ca2+.

  British journal of pharmacology 20030701

• Basic science of closed head injuries and spinal cord injuries.

  Clinics in sports medicine 20030701

• 11,12-epoxyeicosatrienoic acid attenuates synthesis of prostaglandin E2 in rat monocytes stimulated with lipopolysaccharide.

  Experimental biology and medicine (Maywood, N.J.) 20030701

• Effects of n-3 polyunsaturated fatty acids on indomethacin-induced changes in eicosanoid production and blood flow in the gastric mucosa of rats.

  Prostaglandins, leukotrienes, and essential fatty acids 20030701

• Rethinking nutritional support for persons with cancer cachexia.

  Biological research for nursing 20030701

• Effects of plumbagin on platelet aggregation and platelet-neutrophil interactions.

  Planta medica 20030701

• Platelet-type 12-lipoxygenase activates NF-kappaB in prostate cancer cells.

  Prostaglandins & other lipid mediators 20030701

• Sulfur-related air pollutants induce the generation of platelet-activating factor, 5-lipoxygenase- and cyclooxygenase-products in canine alveolar macrophages via activation of phospholipases A2.

  Prostaglandins & other lipid mediators 20030701

• Effects of BM-573, a novel thromboxane A2 inhibitor, on pulmonary hemodynamics in endotoxic shock.

  Archives of physiology and biochemistry 20030701

• Cross-talk between cytosolic phospholipase A2 alpha (cPLA2 alpha) and secretory phospholipase A2 (sPLA2) in hydrogen peroxide-induced arachidonic acid release in murine mesangial cells: sPLA2 regulates cPLA2 alpha activity that is responsible for arachidonic acid release.

  The Journal of biological chemistry 20030627

• Evidence for a role for Galphai1 in mediating weak agonist-induced platelet aggregation in human platelets: reduced Galphai1 expression and defective Gi signaling in the platelets of a patient with a chronic bleeding disorder.

  Blood 20030615

• Arachidonate release and prostaglandin production by group IVC phospholipase A2 (cytosolic phospholipase A2gamma).

  The Biochemical journal 20030615

• Oxidant-mediated AA release from astrocytes involves cPLA(2) and iPLA(2).

  Free radical biology & medicine 20030615

• Age-independent, gray matter-localized, brain-enhanced oxidative stress in male fischer 344 rats: brain levels of F(2)-isoprostanes and F(4)-neuroprostanes.

  Free radical biology & medicine 20030615

• COX and the control of the pulmonary circulation.

  Thrombosis research 20030615

• Leptin induces apoptosis via ERK/cPLA2/cytochrome c pathway in human bone marrow stromal cells.

  The Journal of biological chemistry 20030613

• Arachidonyl dopamine as a ligand for the vanilloid receptor VR1 of the rat.

  Life sciences 20030613

• Eugenol suppresses cyclooxygenase-2 expression in lipopolysaccharide-stimulated mouse macrophage RAW264.7 cells.

  Life sciences 20030606

• Arachidonic acid cytotoxicity: can arachidonic acid be a physiological mediator of cell death?

  Cell biochemistry and function 20030601

• Flaxseed increased alpha-linolenic and eicosapentaenoic acid and decreased arachidonic acid in serum and tissues of rat dams and offspring.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20030601

• Safety evaluation of sources of docosahexaenoic acid and arachidonic acid for use in infant formulas in newborn piglets.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20030601

• Impact of high flaxseed diet on mitogen-induced proliferation, IL-2 production, cell subsets and fatty acid composition of spleen cells from pregnant and F1 generation Sprague-Dawley rats.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20030601

• Effect of vigabatrin on contractile response to arachidonic acid and prostaglandins in smooth muscle preparations and platelet aggregation in experimental laboratory animals.

  Pharmacological research 20030601

• Importance of arachidonic acid as a mediator of parathyroid gland response.

  Kidney international. Supplement 20030601

• Interaction of low molecular weight group IIA phospholipase A2 with apoptotic human T cells: role of heparan sulfate proteoglycans.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030601

• Proteasome inhibition potentiates CYP2E1-mediated toxicity in HepG2 cells.

  Hepatology (Baltimore, Md.) 20030601

• Effects of endocrine disruptors on arachidonic acid metabolism in rabbit platelets.

  Toxicology and applied pharmacology 20030601

• Chronic lithium administration potentiates brain arachidonic acid signaling at rest and during cholinergic activation in awake rats.

  Journal of neurochemistry 20030601

• Dietary arachidonic acid suppresses bone turnover in contrast to low dosage exogenous prostaglandin E(2) that elevates bone formation in the piglet.

  Prostaglandins, leukotrienes, and essential fatty acids 20030601

• Differential modulation of NMDA-induced calcium transients by arachidonic acid and nitric oxide in cultured hippocampal neurons.

  The European journal of neuroscience 20030601

• Visual function in breast-fed term infants weaned to formula with or without long-chain polyunsaturates at 4 to 6 months: a randomized clinical trial.

  The Journal of pediatrics 20030601

• Early events of the exogenously provided L-Carnitine in murine macrophages, T- and B-lymphocytes: modulation of prostaglandin E1 and E2 production in response to arachidonic acid.

  The Journal of nutritional biochemistry 20030601

• Vaccenic acid (t11-18:1) is converted to c9,t11-CLA in MCF-7 and SW480 cancer cells.

  Lipids 20030601

• Transfer of arachidonic acid from lymphocytes to macrophages.

  Lipids 20030601

• Iron and CYP2E1-dependent oxidative stress and toxicity.

  Alcohol (Fayetteville, N.Y.) 20030601

• The effects of donor brain death on renal function and arachidonic acid metabolism in a large animal model of hypothermic preservation injury.

  Transplantation 20030527

• Chronic hypoxia activates lung 15-lipoxygenase, which catalyzes production of 15-HETE and enhances constriction in neonatal rabbit pulmonary arteries.

  Circulation research 20030516

• Evaluation of the effects of several zoanthamine-type alkaloids on the aggregation of human platelets.

  Bioorganic & medicinal chemistry 20030515

• Calcium-independent phospholipase A2 is required for lysozyme secretion in U937 promonocytes.

  Journal of immunology (Baltimore, Md. : 1950) 20030515

• Theoretical calculations of carbon-oxygen bond dissociation enthalpies of peroxyl radicals formed in the autoxidation of lipids.

  Journal of the American Chemical Society 20030514

• Mechanisms for the formation of isoprostane endoperoxides from arachidonic acid. 'Dioxetane' intermediate versus beta-fragmentation of peroxyl radicals.

  The Journal of biological chemistry 20030509

• Molecular localization of the inhibitory arachidonic acid binding site to the pore of hIK1.

  The Journal of biological chemistry 20030509

• Levuglandinyl adducts of proteins are formed via a prostaglandin H2 synthase-dependent pathway after platelet activation.

  The Journal of biological chemistry 20030509

• Synthesis and structure-activity relationships of cis-tetrahydrophthalazinone/pyridazinone hybrids: a novel series of potent dual PDE3/PDE4 inhibitory agents.

  Journal of medicinal chemistry 20030508

• Anti-inflammatory activity of erycristagallin, a pterocarpene from Erythrina mildbraedii.

  European journal of pharmacology 20030502

• CYP4A metabolites of arachidonic acid and VEGF are mediators of skeletal muscle angiogenesis.

  American journal of physiology. Heart and circulatory physiology 20030501

• Attenuation of glucocorticoid functions in an Anx-A1-/- cell line.

  The Biochemical journal 20030501

• Preformed enzymes in mast cell granules and their potential role in allergic rhinitis.

  Current allergy and asthma reports 20030501

• Arachidonic acid activates an open rectifier potassium channel in cultured rat cortical astrocytes.

  Journal of neuroscience research 20030501

• Valproic acid down-regulates the conversion of arachidonic acid to eicosanoids via cyclooxygenase-1 and -2 in rat brain.

  Journal of neurochemistry 20030501

• Human group IIA secretory phospholipase A2 potentiates Ca2+ influx through L-type voltage-sensitive Ca2+ channels in cultured rat cortical neurons.

  Journal of neurochemistry 20030501

• Biphasic regulation of renal proximal bicarbonate absorption by luminal AT(1A) receptor.

  Journal of the American Society of Nephrology : JASN 20030501

• The effects on plasma, red cell and platelet fatty acids of taking 12 g/day of ethyl-eicosapentaenoate for 16 months: dihomogammalinolenic, arachidonic and docosahexaenoic acids and relevance to Inuit metabolism.

  Prostaglandins, leukotrienes, and essential fatty acids 20030501

• Synergistic effect of D-003 and aspirin on experimental thrombosis models.

  Prostaglandins, leukotrienes, and essential fatty acids 20030501

• Augmentation of staphylococcal alpha-toxin signaling by the epidermal platelet-activating factor receptor.

  The Journal of investigative dermatology 20030501

• Does the release of arachidonic acid from cells play a role in cancer chemoprevention?

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030501

• Elevated expression of 12/15-lipoxygenase and cyclooxygenase-2 in a transgenic mouse model of prostate carcinoma.

  Cancer research 20030501

• The COX-2 selective inhibitor, valdecoxib, does not impair platelet function in the elderly: results of a randomized controlled trial.

  Journal of clinical pharmacology 20030501

• Proton conduction through full-length gp91phox requires histidine 115.

  Protoplasma 20030501

• Tissue essential fatty acid composition and competitive response to dietary manipulations in white bass (Morone chrysops), striped bass (M. saxatilis) and hybrid striped bass (M. chrysopsxM. saxatilis).

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20030501

• COX-LOX inhibition: current evidence for an emerging new therapy.

  International journal of clinical practice 20030501

• [Reduction in n-3 PUFA levels and EPA/AA ratio in serum after desert travels in China].

  Nihon eiseigaku zasshi. Japanese journal of hygiene 20030501

• Pharmacological studies on resveratrol.

  Methods and findings in experimental and clinical pharmacology 20030501

• Microbial synthesis of trans isomer of eicosapentaenoic acid (EPA) from the chemically synthesized trans isomer of linolenic acid by a delta12 desaturase-defective mutant of Mortierella alpina 1S-4.

  Bioscience, biotechnology, and biochemistry 20030501

• Relative potencies of statins in reducing cholesterol synthesis and enhancing linoleic acid metabolism.

  European journal of pharmacology 20030425

• Role of brain thromboxane A2 in the release of noradrenaline and adrenaline from adrenal medulla in rats.

  European journal of pharmacology 20030425

• Arachidonic acid-induced IL-6 expression is mediated by PKC alpha activation in osteoblastic cells.

  Biochemistry 20030422

• Concomitant recruitment of ERK1/2 and p38 MAPK signalling pathway is required for activation of cytoplasmic phospholipase A2 via ATP in articular chondrocytes.

  The Journal of biological chemistry 20030418

• Identification of all classes of spin-trapped carbon-centered radicals in soybean lipoxygenase-dependent lipid peroxidations of omega-6 polyunsaturated fatty acids via LC/ESR, LC/MS, and tandem MS.

  Free radical biology & medicine 20030415

• Lycopene attenuates arachidonic acid toxicity in HepG2 cells overexpressing CYP2E1.

  Biochemical and biophysical research communications 20030411

• Vascular permeabilization by intravenous arachidonate in the rat peritoneal cavity: antagonism by antioxidants.

  European journal of pharmacology 20030411

• Vascular permeabilization by intravenous arachidonate in the rat peritoneal cavity: antagonism by ethamsylate.

  European journal of pharmacology 20030411

• Ni2+ enhances Fe2+/peroxide-induced oxidation of arachidonic acid and formation of geno/cytotoxic 4-hydroxynonenal: a possible contributory mechanism in nickel toxicity and allergenicity.

  Biochimica et biophysica acta 20030407

• 12-lipoxygenase in opioid-induced delayed cardioprotection: gene array, mass spectrometric, and pharmacological analyses.

  Circulation research 20030404

• BAX and BAK regulation of endoplasmic reticulum Ca2+: a control point for apoptosis.

  Science (New York, N.Y.) 20030404

• Inhibitory effects of total flavones of Hippophae Rhamnoides L on thrombosis in mouse femoral artery and in vitro platelet aggregation.

  Life sciences 20030404

• Pharmaco-toxicological study of diterpenoids.

  Bioorganic & medicinal chemistry 20030403

• Inhibition of protein kinase C by synthetic xanthone derivatives.

  Bioorganic & medicinal chemistry 20030403

• A newly established in vitro culture using transgenic Drosophila reveals functional coupling between the phospholipase A2-generated fatty acid cascade and lipopolysaccharide-dependent activation of the immune deficiency (imd) pathway in insect immunity.

  The Biochemical journal 20030401

• Acute hypoxia occludes hTREK-1 modulation: re-evaluation of the potential role of tandem P domain K+ channels in central neuroprotection.

  The Journal of physiology 20030401

• Arachidonic acid in astrocytes blocks Ca(2+) oscillations by inhibiting store-operated Ca(2+) entry, and causes delayed Ca(2+) influx.

  Cell calcium 20030401

• Role of oxidative stress in angiotensin-induced hypertension.

  American journal of physiology. Regulatory, integrative and comparative physiology 20030401

• Anti-leukotriene drugs in the prevention and treatment of hepatorenal syndrome.

  Prostaglandins, leukotrienes, and essential fatty acids 20030401

• The stable analog carbocyclic TXA2 but not platelet-released TXA2 induces osteoclast-like cell formation.

  Prostaglandins, leukotrienes, and essential fatty acids 20030401

• Crosstalk between nitric oxide synthase and cyclooxygenase metabolites in the estrogenized rat uterus.

  Prostaglandins, leukotrienes, and essential fatty acids 20030401

• Glucuronides of tea catechins: enzymology of biosynthesis and biological activities.

  Drug metabolism and disposition: the biological fate of chemicals 20030401

• Mechanisms of accumulation of arachidonate in phosphatidylinositol in yellowtail. A comparative study of acylation systems of phospholipids in rat and the fish species Seriola quinqueradiata.

  European journal of biochemistry 20030401

• Creating conditions similar to those that occur during exposure of cells to microgravity induces apoptosis in human lymphocytes by 5-lipoxygenase-mediated mitochondrial uncoupling and cytochrome c release.

  Journal of leukocyte biology 20030401

• Arachidonic acid activates phospholipase D in human neutrophils; essential role of endogenous leukotriene B4 and inhibition by adenosine A2A receptor engagement.

  Journal of leukocyte biology 20030401

• Efficacy and safety of docosahexaenoic acid and arachidonic acid addition to infant formulas: can one buy better vision and intelligence?

  Journal of the American College of Nutrition 20030401

• Further evidence that the CCK2 receptor is coupled to two transduction pathways using site-directed mutagenesis.

  Journal of neurochemistry 20030401

• The p42/44mitogen-activated protein kinase inhibitor PD 98059, but not U 0126, increases a K+ current in cardiomyocytes.

  Clinical and experimental pharmacology & physiology 20030401

• Polyunsaturated fatty acids and cytokine profiles: a clue to the changing prevalence of atopy?

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20030401

• Crystal-induced neutrophil activation: VIII. Immediate production of prostaglandin E2 mediated by constitutive cyclooxygenase 2 in human neutrophils stimulated by urate crystals.

  Arthritis and rheumatism 20030401

• Agonist-specific coupling of a cloned human alpha1A-adrenoceptor to different second messenger pathways.

  Naunyn-Schmiedeberg's archives of pharmacology 20030401

• Platelets may inhibit leucotriene biosynthesis by human neutrophils at the integrin level.

  British journal of haematology 20030401

• Platelets abrogate leukotriene B(4) generation by human blood neutrophils stimulated with monosodium urate monohydrate or f-Met-Leu-Phe in vitro.

  Laboratory investigation; a journal of technical methods and pathology 20030401

• Long-chain n-3 fatty acids and inflammation: potential application in surgical and trauma patients.

  Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20030401

• Antiplatelet and anti-HIV constituents from Euchresta formosana.

  Natural product research 20030401

• Involvement of arachidonic acid in nonimmunologic production of superoxide in mast cells.

  International archives of allergy and immunology 20030401

• A model with original conditions and materials to test potential inhibitors of cyclooxygenase-2 versus cyclooxygenase-1 in isolated human blood cells.

  Methods and findings in experimental and clinical pharmacology 20030401

• Membrane oxidation assay--a novel lipoxygenase-based evaluation of membrane oxidizability.

  Free radical research 20030401

• The regulation of arachidonic acid metabolism in human first trimester trophoblast by cyclic AMP.

  Prostaglandins & other lipid mediators 20030401

• Effect of luteinizing hormone (LH), pregnancy specific protein B (PSPB), or arachidonic acid (AA) on ovine endometrium of the estrous cycle or placental secretion of prostaglandins E2 (PGE2) and F2alpha (PGF2alpha) and progesterone in vitro.

  Prostaglandins & other lipid mediators 20030401

• Conformationally constrained butyrophenones as new pharmacological tools to study 5-HT 2A and 5-HT 2C receptor behaviours.

  European journal of medicinal chemistry 20030401

• Simultaneous determination of 4-hydroxy-2-alkenals, lipid peroxidation toxic products.

  Food additives and contaminants 20030401

• Heat shock preconditioning modulates proliferation and apoptosis after superficial injury in isolated guinea pig gastric mucosa via an eicosanoid and protein synthesis-dependent mechanism.

  APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20030401

• Gene cloning and functional analysis of a second delta 6-fatty acid desaturase from an arachidonic acid-producing Mortierella fungus.

  Bioscience, biotechnology, and biochemistry 20030401

• Increased response of liver microsomal delta 6-desaturase activity to dietary methionine in rats.

  Bioscience, biotechnology, and biochemistry 20030401

• Regulation of cytosolic phospholipase A2, cyclooxygenase-1 and -2 expression by PMA, TNFalpha, LPS and M-CSF in human monocytes and macrophages.

  Molecular and cellular biochemistry 20030401

• The potential role for arachidonic and docosahexaenoic acids in protection against some central nervous system injuries in preterm infants.

  Lipids 20030401

• A biomarker of n-3 compliance in patients taking fish oil for rheumatoid arthritis.

  Lipids 20030401

• Docosapentaenoic acid does not completely replace DHA in n-3 FA-deficient rats during early development.

  Lipids 20030401

• [Changes in fatty acid composition of serum cholesteryl esters in patients with chronic heart failure].

  Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University 20030401

• The newly synthesized linoleic acid derivative FR236924 induces a long-lasting facilitation of hippocampal neurotransmission by targeting nicotinic acetylcholine receptors.

  Bioorganic & medicinal chemistry letters 20030324

• Cellular arachidonate-releasing function of novel classes of secretory phospholipase A2s (groups III and XII).

  The Journal of biological chemistry 20030321

• Ca2+ selectivity and fatty acid specificity of the noncapacitative, arachidonate-regulated Ca2+ (ARC) channels.

  The Journal of biological chemistry 20030321

• How does prolonged caloric restriction ameliorate age-related impairment of long-term potentiation in the hippocampus?

  Brain research. Molecular brain research 20030317

• Paracetamol effectively reduces prostaglandin E2 synthesis in brain macrophages by inhibiting enzymatic activity of cyclooxygenase but not phospholipase and prostaglandin E synthase.

  Journal of neuroscience research 20030315

• Effect of the lipid peroxidation product acrolein on tau phosphorylation in neural cells.

  Journal of neuroscience research 20030315

• Identification and regulation of a new vertebrate cytochrome P450 subfamily, the CYP2Ps, and functional characterization of CYP2P3, a conserved arachidonic acid epoxygenase/19-hydroxylase.

  Archives of biochemistry and biophysics 20030315

• Antiplatelet activity of synthetic pyrrolo-benzylisoquinolines.

  Bioorganic & medicinal chemistry letters 20030310

• Human group IVC phospholipase A2 (cPLA2gamma). Roles in the membrane remodeling and activation induced by oxidative stress.

  The Journal of biological chemistry 20030307

• Fatty acid release and oxidation are factors in lipoxygenase inhibitor-induced apoptosis.

  Toxicology letters 20030303

• Melatonin preserves arachidonic and docosapentaenoic acids during ascorbate-Fe2+ peroxidation of rat testis microsomes and mitochondria.

  The international journal of biochemistry & cell biology 20030301

• Roles of Rac and cytosolic phospholipase A2 in the intracellular signalling in response to titanium particles.

  Cellular signalling 20030301

• The effect of propofol on the interaction of platelets with leukocytes and erythrocytes in surgical patients.

  Anesthesia and analgesia 20030301

• Zona pellucida induces activation of phospholipase A2 during acrosomal exocytosis in guinea pig spermatozoa.

  Biology of reproduction 20030301

• Smoking, gender, and dietary influences on erythrocyte essential fatty acid composition among patients with schizophrenia or schizoaffective disorder.

  Biological psychiatry 20030301

• Cyclooxygenase-1 is overexpressed and promotes angiogenic growth factor production in ovarian cancer.

  Cancer research 20030301

• Effect of unsaturated fatty acid on muscarinic current in guinea pig gastric antral circular myocytes.

  Acta pharmacologica Sinica 20030301

• Fatty acid oxidation products in human atherosclerotic plaque: an analysis of clinical and histopathological correlates.

  Atherosclerosis 20030301

• Congenital malformations in offspring of diabetic mothers--animal and human studies.

  Reviews in endocrine & metabolic disorders 20030301

• Tissue kallikrein actions at the rabbit natural or recombinant kinin B2 receptors.

  Hypertension (Dallas, Tex. : 1979) 20030301

• Mediation of arachidonic acid metabolite(s) produced by endothelial cytochrome P-450 3A4 in monkey arterial relaxation.

  Hypertension research : official journal of the Japanese Society of Hypertension 20030301

• Antiplatelet activities of aporphine alkaloids isolated from leaves of Magnolia obovata.

  Planta medica 20030301

• Inhibition of leukotriene synthesis, pharmacokinetics, and tolerability of a novel dietary fatty acid formulation in healthy adult subjects.

  Clinical therapeutics 20030301

• Enhanced generation of leukotriene B4 from calcium ionophore-stimulated rat peritoneal inflammatory cells: a possible clinical relevance.

  Current drug targets. Inflammation and allergy 20030301

• Liquid chromatographic-mass spectrometric determination of cyclooxygenase metabolites of arachidonic acid in cultured cells.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030225

• Tau polymerization: role of the amino terminus.

  Biochemistry 20030225

• Induction of 5-lipoxygenase activation in polymorphonuclear leukocytes by 1-oleoyl-2-acetylglycerol.

  Biochimica et biophysica acta 20030220

• Expression of cytochromes P450 4F4 and 4F5 in infection and injury models of inflammation.

  Biochimica et biophysica acta 20030217

• Metallothionein 2A induction by zinc protects HEPG2 cells against CYP2E1-dependent toxicity.

  Free radical biology & medicine 20030215

• Nitric oxide-mediated arachidonic acid release from perifused Venus verrucosa oocytes.

  General and comparative endocrinology 20030215

• PGE2 reduces arachidonic acid release in murine podocytes: evidence for an autocrine feedback loop.

  American journal of physiology. Cell physiology 20030201

• Basic fibroblast growth factor upregulates cyclooxygenase-2 in I407 cells through p38 MAP kinase.

  American journal of physiology. Gastrointestinal and liver physiology 20030201

• Arachidonic acid metabolites and an early stage of pulmonary hypertension in chronically hypoxic newborn pigs.

  American journal of physiology. Lung cellular and molecular physiology 20030201

• Abnormalities in intracellular Ca2+ regulation in fetal vascular smooth muscle in pre-eclampsia: enhanced sensitivity to arachidonic acid.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030201

• The bacterium Xenorhabdus nematophilus depresses nodulation reactions to infection by inhibiting eicosanoid biosynthesis in tobacco hornworms, Manduca sexta.

  Archives of insect biochemistry and physiology 20030201

• Role of arachidonic acid and protein kinase C during maturation-inducing hormone-dependent meiotic resumption and ovulation in ovarian follicles of Atlantic croaker.

  Biology of reproduction 20030201

• Hormonal modulation of delta6 and delta5 desaturases: case of diabetes.

  Prostaglandins, leukotrienes, and essential fatty acids 20030201

• Inhibition of prostaglandin H2 synthases by salicylate is dependent on the oxidative state of the enzymes.

  The Journal of pharmacology and experimental therapeutics 20030201

• Norepinephrine-induced stimulation of p38 mitogen-activated protein kinase is mediated by arachidonic acid metabolites generated by activation of cytosolic phospholipase A(2) in vascular smooth muscle cells.

  The Journal of pharmacology and experimental therapeutics 20030201

• Differentiation and apoptosis in human immortalized sebocytes.

  The Journal of investigative dermatology 20030201

• Arachidonic acid and anandamide have opposite modulatory actions at the glycine transporter, GLYT1a.

  Journal of neurochemistry 20030201

• Palmitic and stearic fatty acids induce caspase-dependent and -independent cell death in nerve growth factor differentiated PC12 cells.

  Journal of neurochemistry 20030201

• Ex vivo synergy of arachidonate-enriched serum with ceftazidime and amikacin on multidrug-resistant Pseudomonas aeruginosa.

  The Journal of antimicrobial chemotherapy 20030201

• Kidney CYP450 enzymes: biological actions beyond drug metabolism.

  Current drug metabolism 20030201

• Arachidonic acid and prostacyclin signaling promote adipose tissue development: a human health concern?

  Journal of lipid research 20030201

• PPARbeta regulates vitamin A metabolism-related gene expression in hepatic stellate cells undergoing activation.

  Journal of lipid research 20030201

• Human immunodeficiency virus type 1 gp120 and ethanol coexposure in rat organotypic brain slice cultures: Curtailment of gp120-induced neurotoxicity and neurotoxic mediators by moderate but not high ethanol concentrations.

  Journal of neurovirology 20030201

• Aldehyde dehydrogenase 3 expression is decreased by clofibrate via PPAR gamma induction in JM2 rat hepatoma cell line.

  Chemico-biological interactions 20030201

• Arachidonic acid-induced channel- and carrier-type ion transport across planar bilayer lipid membranes.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20030201

• Prostaglandin production from arachidonic acid and evidence for a 9,11-endoperoxide prostaglandin H2 reductase in Leishmania.

  International journal for parasitology 20030201

• Diatom cultivation and biotechnologically relevant products. Part II: current and putative products.

  Applied microbiology and biotechnology 20030201

• [Asthma and aspirin].

  Recenti progressi in medicina 20030201

• A new dual inhibitor of arachidonate metabolism isolated from Helichrysum italicum.

  European journal of pharmacology 20030124

• Mechanisms of enhanced macrophage-mediated prostaglandin E2 production and its suppressive role in Th1 activation in Th2-dominant BALB/c mice.

  Journal of immunology (Baltimore, Md. : 1950) 20030115

• Role of p38 MAPK in CYP2E1-dependent arachidonic acid toxicity.

  The Journal of biological chemistry 20030110

• Discovery of a thieno[2,3-d]pyrimidine-2,4-dione bearing a p-methoxyureidophenyl moiety at the 6-position: a highly potent and orally bioavailable non-peptide antagonist for the human luteinizing hormone-releasing hormone receptor.

  Journal of medicinal chemistry 20030102

• Carnitine inhibits arachidonic acid turnover, platelet function, and oxidative stress.

  American journal of physiology. Heart and circulatory physiology 20030101

• Transfection of CYP4A1 cDNA increases vascular reactivity in renal interlobar arteries.

  American journal of physiology. Renal physiology 20030101

• Distribution of cytochrome P-450 4A and 4F isoforms along the nephron in mice.

  American journal of physiology. Renal physiology 20030101

• Neural cell adhesion molecule-mediated neurite outgrowth is repressed by overexpression of HES-1.

  Journal of neuroscience research 20030101

• Eicosanoids in insect immunity: bacterial infection stimulates hemocytic phospholipase A2 activity in tobacco hornworms.

  Archives of insect biochemistry and physiology 20030101

• Arachidonic acid-induced vasodilation of rat small mesenteric arteries is lipoxygenase-dependent.

  The Journal of pharmacology and experimental therapeutics 20030101

• Serotonin 5-hydroxytryptamine 2A receptor-coupled phospholipase C and phospholipase A2 signaling pathways have different receptor reserves.

  The Journal of pharmacology and experimental therapeutics 20030101

• Analysis of differential substrate selectivities of CYP2B6 and CYP2E1 by site-directed mutagenesis and molecular modeling.

  The Journal of pharmacology and experimental therapeutics 20030101

• Block of erg current by linoleoylamide, a sleep-inducing agent, in pituitary GH3 cells.

  European journal of pharmacology 20030101

• Cytochrome P450 2E1 responsiveness in the promoter of glutamate-cysteine ligase catalytic subunit.

  Hepatology (Baltimore, Md.) 20030101

• Cyclooxygenase-derived products modulate the increased intrahepatic resistance of cirrhotic rat livers.

  Hepatology (Baltimore, Md.) 20030101

• Cyclic-AMP agonists inhibit antiphospholipid/beta2-glycoprotein I induced synthesis of human platelet thromboxane A2 in vitro.

  The Journal of rheumatology 20030101

• The active metabolite of leflunomide, A77 1726, inhibits the production of prostaglandin E(2), matrix metalloproteinase 1 and interleukin 6 in human fibroblast-like synoviocytes.

  Rheumatology (Oxford, England) 20030101

• Brain lipid metabolism in the cPLA2 knockout mouse.

  Journal of lipid research 20030101

• Antidiabetic actions of arachidonic acid and zinc in genetically diabetic Goto-Kakizaki rats.

  Metabolism: clinical and experimental 20030101

• Cell type-dependent activation of 5-lipoxygenase by arachidonic acid.

  Journal of leukocyte biology 20030101

• Pertussis toxin-sensitive secretory phospholipase A2 expression and motility in activated primary human keratinocytes.

  The Journal of investigative dermatology 20030101

• Association between E-cadherin expression by human colon, bladder and breast cancer cells and the 13-HODE:15-HETE ratio. A possible role of their metastatic potential.

  Prostaglandins, leukotrienes, and essential fatty acids 20030101

• Regional biosynthesis of prostaglandins and hydroxyeicosatetraenoic acids from arachidonic acid in the rat stomach tissue.

  Prostaglandins, leukotrienes, and essential fatty acids 20030101

• Genetic variation in cyclooxygenase 1: effects on response to aspirin.

  Clinical pharmacology and therapeutics 20030101

• An inexpensive medium for production of arachidonic acid by Mortierella alpina.

  Journal of industrial microbiology & biotechnology 20030101

• Long-chain polyunsaturated fatty acids at birth and cognitive function at 7 y of age.

  European journal of clinical nutrition 20030101

• Anti-inflammatory effects of a low arachidonic acid diet and fish oil in patients with rheumatoid arthritis.

  Rheumatology international 20030101

• Nitric oxide production and arachidonic acid metabolism in platelet membranes of coronary heart disease patients with and without diabetes.

  Medical principles and practice : international journal of the Kuwait University, Health Science Centre 20030101

• Influence of changes in dietary fatty acids during pregnancy on placental and fetal fatty acid profile in the rat.

  Biology of the neonate 20030101

• Influence of dietary linoleic acid intake with different fat intakes on arachidonic acid concentrations in plasma and platelet lipids and eicosanoid biosynthesis in female volunteers.

  Annals of nutrition & metabolism 20030101

• Cell volume induced hormone secretion: studies on signal transduction and specificity.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20030101

• Eicosanoid precursor polyenoic fatty acids modulate synaptic levels of dopamine in ex-vivo slices of rat brain striatum.

  In vivo (Athens, Greece) 20030101

• [Effect of inhibitors of cyclooxygenase and lypoxygenase pathway of metabolism of arachidonic acid on the development and suppression of the immune response in mice].

  Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20030101

• Progesterone regulates IL12 expression in pregnancy lymphocytes by inhibiting phospholipase A2.

  American journal of reproductive immunology (New York, N.Y. : 1989) 20030101

• Cytochrome P450 arachidonic acid metabolites modulate renal tubular function.

  Advances in experimental medicine and biology 20030101

• Arachidonic acid inhibits cysteinyl-leukotriene receptor activation in human pulmonary vessels.

  Advances in experimental medicine and biology 20030101

• Cellular arachidonate-releasing functions of various phospholipase A2s.

  Advances in experimental medicine and biology 20030101

• 5-Lipoxygenase activation by MAPKAPK-2 and ERKs.

  Advances in experimental medicine and biology 20030101

• Isomerization and nitro-oxidation of arachidonic acid by NO2.

  Advances in experimental medicine and biology 20030101

• Phospholipase A2 modulates respiratory burst developed by neutrophils in patients with rheumatoid arthritis.

  Journal of cellular and molecular medicine 20030101

• Models of acute inflammation in the ear.

  Methods in molecular biology (Clifton, N.J.) 20030101

• [Special features of NSAID intolerance in children].

  Allergologia et immunopathologia 20030101

• Regulation of cytosolic phospholipase A(2) translocation.

  Advances in enzyme regulation 20030101

• Inflammation: a novel mechanism for the transport of extracellular nucleotide-induced arachidonic acid by S100A8/A9 for transcellular metabolism.

  Cell biology international 20030101

• Lipid peroxidation by Pseudomonas aeruginosa in the pathogenesis of nosocomial sepsis.

  Journal of postgraduate medicine 20030101

• Epidermal growth factor regulates Ca2+ uptake in primary cultured renal proximal tubule cells: involvement of cAMP, PKC and cPLA2.

  Kidney & blood pressure research 20030101

• Products of arachidonic acid metabolism.

  Methods in molecular medicine 20030101

• [Participation of nitric oxide and arachidonic acid metabolites via cytochrome - P450 in the regulation of arterial blood pressure].

  Archivos de cardiologia de Mexico 20030101

• 5-lipoxygenase and FLAP.

  Prostaglandins, leukotrienes, and essential fatty acids 20030101

• The role of leukotrienes in asthma.

  Prostaglandins, leukotrienes, and essential fatty acids 20030101

• Cyclooxygenase enzymes in allergic inflammation and asthma.

  Prostaglandins, leukotrienes, and essential fatty acids 20030101

• The role of mast cells in asthma.

  Prostaglandins, leukotrienes, and essential fatty acids 20030101

• Polymorphic light eruption.

  Dermatologic therapy 20030101

• Itch associated with skin disease: advances in pathophysiology and emerging therapies.

  American journal of clinical dermatology 20030101

• [Lipid complex in subpalatine tonsils in normal state and pathology].

  Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20030101

• [Fatty acids from the sponge Halichondria panicea from the Sea of Japan].

  Bioorganicheskaia khimiia 20030101

• Tamoxifen stimulates arachidonic acid release from rat liver cells by an estrogen receptor-independent, non-genomic mechanism.

  BMC cancer 20030101

• Detection of enhanced monohydroxyeicosatetraenoic acid and F2-isoprostane levels in human plasma samples after extracorporeal photoimmunotherapy.

  Skin pharmacology and applied skin physiology 20030101

• Identification of an endogenous inhibitor of arachidonate metabolism in human epidermoid carcinoma A431 cells.

  Journal of biomedical science 20030101

• [Ontogenic characteristics of changes in fatty acid composition of the liver lipids as a main substrate for peroxidation in geese].

  Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20030101

• Neutrophil chemotaxis: potential role of chemokine receptors in extracellular nucleotide induced Mac-1 expression.

  Medical hypotheses 20030101

• Effect of epidermal growth factor on phosphate uptake in renal proximal tubule cells: involvement of PKC, MAPK, and cPLA2.

  Kidney & blood pressure research 20030101

• Advanced age, but not anergy, is associated with altered serum polyunsaturated fatty acid levels.

  The journal of nutrition, health & aging 20030101

• Oxygen sensing by human recombinant tandem-P domain potassium channels.

  Advances in experimental medicine and biology 20030101

• [Effect of GABA on phosphoinositide cycle and membrane lipid modification in the brain synaptosomes of rats in hypokinesia].

  Eksperimental'naia i klinicheskaia farmakologiia 20030101

• Candida bombicola cells immobilized on patterned lipid films as enzyme sources for the transformation of arachidonic acid to 20-HETE.

  Biotechnology progress 20030101

• [Synthesis of eicosanoids in the colonic mucosa in patients with ulcerative colitis].

  Klinicheskaia meditsina 20030101

• Analysis of cyclooxygenase 2 (COX-2) expression during malignant melanoma progression.

  Cancer biology & therapy 20030101

• Effects of green tea and high-fat diet on arachidonic acid metabolism and aberrant crypt foci formation in an azoxymethane-induced colon carcinogenesis mouse model.

  Nutrition and cancer 20030101

• Effective anti-platelet and COX-1 enzyme inhibitors from pungent constituents of ginger.

  Thrombosis research 20030101

• [Specificity of endometrium phospholipids and their fatty acids changes in the development of hyperplasia].

  Likars'ka sprava 20030101

• Mutations within the cyclooxygenase-1 gene in aspirin non-responders with recurrence of stroke.

  Thrombosis research 20030101

• [Signaling role of exogenous arachidonic acid in the invasion of macrophages by Toxoplasma gondii].

  Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 20030101

• The cyclooxygenase reaction mechanism.

  Biochemistry 20021231

• Structural changes are induced in human neutrophil cytochrome b by NADPH oxidase activators, LDS, SDS, and arachidonate: intermolecular resonance energy transfer between trisulfopyrenyl-wheat germ agglutinin and cytochrome b(558).

  Biochimica et biophysica acta 20021223

• Prostaglandin E2 induces hypoxia-inducible factor-1alpha stabilization and nuclear localization in a human prostate cancer cell line.

  The Journal of biological chemistry 20021220

• Prostaglandin production from arachidonic acid and evidence for a 9,11-endoperoxide prostaglandin H2 reductase in Leishmania.

  International journal for parasitology 20021219

• Toward a unified scheme for the aggregation of tau into Alzheimer paired helical filaments.

  Biochemistry 20021217

• Ca2+-dependent and independent mitochondrial damage in HepG2 cells that overexpress CYP2E1.

  Archives of biochemistry and biophysics 20021215

• Design, synthesis, and antioxidant activity of FeAOX-6, a novel agent deriving from a molecular combination of the chromanyl and polyisoprenyl moieties.

  Free radical biology & medicine 20021215

• Arachidonic acid stimulates internalisation of leptin by human placental choriocarcinoma (BeWo) cells.

  Biochemical and biophysical research communications 20021206

• Aspirin (ASA) regulates 5-lipoxygenase activity and peroxisome proliferator-activated receptor alpha-mediated CINC-1 release in rat liver cells: novel actions of lipoxin A4 (LXA4) and ASA-triggered 15-epi-LXA4.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20021201

• Calcium-independent phospholipase A2 through arachidonic acid mobilization is involved in Caco-2 cell growth.

  Journal of cellular physiology 20021201

• Downregulation of nNOS and synthesis of PGs associated with endotoxin-induced delay in gastric emptying.

  American journal of physiology. Gastrointestinal and liver physiology 20021201

• Oxidative stress induces arachidonate release from human lung cells through the epithelial growth factor receptor pathway.

  American journal of respiratory cell and molecular biology 20021201

• Arachidonate geometrical isomers generated by thiyl radicals: the relationship with trans lipids detected in biological samples.

  Free radical biology & medicine 20021201

• Decrease of inward rectification as a mechanism for arachidonic acid-induced potentiation of hKir2.3.

  European biophysics journal : EBJ 20021201

• Effect of arachidonic and eicosapentaenoic acids on acute lung injury induced by hypochlorous acid.

  Thorax 20021201

• Characterization and identification of cytochrome P450 metabolites of arachidonic acid released by human peritoneal macrophages obtained from the pouch of Douglas.

  Prostaglandins, leukotrienes, and essential fatty acids 20021201

• Nuclear receptor agonists stimulate release of arachidonic acid from rat liver cells.

  Prostaglandins, leukotrienes, and essential fatty acids 20021201

• Colonic anti-inflammatory mechanisms of conjugated linoleic acid.

  Clinical nutrition (Edinburgh, Scotland) 20021201

• Brain incorporation of [11C]arachidonic acid in young healthy humans measured with positron emission tomography.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20021201

• Effects of polyunsaturated fatty acids on voltage-gated K+ and Na+ channels in rat olfactory receptor neurons.

  The European journal of neuroscience 20021201

• Peroxynitrite stimulates the activity of cytosolic phospholipase A2 in U937 cells: the extent of arachidonic acid formation regulates the balance between cell survival or death.

  Cell death and differentiation 20021201

• Intramolecular signal transduction by the bradykinin B2 receptor.

  International immunopharmacology 20021201

• Kallikreins when activating bradykinin B2 receptor induce its redistribution on plasma membrane.

  International immunopharmacology 20021201

• The influence of MK-801 on the hippocampal free arachidonic acid level and Na+,K+-ATPase activity in global cerebral ischemia-exposed rats.

  Progress in neuro-psychopharmacology & biological psychiatry 20021201

• Aberrant arachidonic acid metabolism in esophageal adenocarcinogenesis, and the effects of sulindac, nordihydroguaiaretic acid, and alpha-difluoromethylornithine on tumorigenesis in a rat surgical model.

  Carcinogenesis 20021201

• The eicosanoid factor: a determinant of individuality of nephron segments.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20021201

• Heat-shock preconditioning affects restitution of isolated guinea pig gastric mucosa by an arachidonic acid and protein synthesis dependent mechanism.

  Scandinavian journal of gastroenterology 20021201

• Evidence for the involvement of the unique C-tail of S100A9 in the binding of arachidonic acid to the heterocomplex S100A8/A9.

  Biological chemistry 20021201

• Oxidative stability of polyunsaturated fatty acid in phosphatidylcholine liposomes.

  Bioscience, biotechnology, and biochemistry 20021201

• beta-Adrenergic stimulation controls the expression of a thioesterase specific for very-long-chain fatty acids in perfused hearts.

  Biochemical and biophysical research communications 20021122

• Potassium-evoked glutamate release liberates arachidonic acid from cortical neurons.

  The Journal of biological chemistry 20021115

• Capillary electrophoresis of cytochrome P-450 epoxygenase metabolites of arachidonic acid. 2. Resolution of stereoisomers.

  Analytical chemistry 20021115

• Excitatory amino acid transporters: keeping up with glutamate.

  Neurochemistry international 20021101

• Complement C5b-9 membrane attack complex increases expression of endoplasmic reticulum stress proteins in glomerular epithelial cells.

  The Journal of biological chemistry 20021101

• Nitric oxide inhibits renal cytochrome P450-dependent epoxygenases in the rat.

  Clinical and experimental pharmacology & physiology 20021101

• Effect of three triterpenoids, lupeol, betulin, and betulinic acid on the stimulus-induced superoxide generation and tyrosyl phosphorylation of proteins in human neutrophils.

  Clinica chimica acta; international journal of clinical chemistry 20021101

• Phospholipid metabolite production in human urothelial cells after protease-activated receptor cleavage.

  American journal of physiology. Renal physiology 20021101

• Modulation of BK(Ca) channel activity by fatty acids: structural requirements and mechanism of action.

  American journal of physiology. Cell physiology 20021101

• Expression analysis of the two ferrochelatase genes in Arabidopsis in different tissues and under stress conditions reveals their different roles in haem biosynthesis.

  Plant molecular biology 20021101

• Does increased leukotriene B4 in type 1 diabetes result from elevated cholesteryl ester transfer protein activity?

  Medical hypotheses 20021101

• Involvement of CYP2J2 on the intestinal first-pass metabolism of antihistamine drug, astemizole.

  Drug metabolism and disposition: the biological fate of chemicals 20021101

• Systemic fatty acid responses to transient focal cerebral ischemia: influence of neuroprotectant therapy with human albumin.

  Journal of neurochemistry 20021101

• Mechanisms of epidermal growth factor signaling: regulation of steroid biosynthesis and the steroidogenic acute regulatory protein in mouse Leydig tumor cells.

  Biology of reproduction 20021101

• Adenosine up-regulates cyclooxygenase-2 in human granulocytes: impact on the balance of eicosanoid generation.

  Journal of immunology (Baltimore, Md. : 1950) 20021101

• Inhibition of prostaglandin E(2) production by taiwanin C isolated from the root of Acanthopanax chiisanensis and the mechanism of action.

  Biochemical pharmacology 20021101

• Intrauterine growth restriction is associated with changes in polyunsaturated fatty acid fetal-maternal relationships.

  Pediatric research 20021101

• Effects of tanshinone I isolated from Salvia miltiorrhiza bunge on arachidonic acid metabolism and in vivo inflammatory responses.

  Phytotherapy research : PTR 20021101

• Biphasic regulation of Na+-HCO3- cotransporter by angiotensin II type 1A receptor.

  Hypertension (Dallas, Tex. : 1979) 20021101

• Role of three isoforms of phospholipase A2 in capacitative calcium influx in human T-cells.

  European journal of biochemistry 20021101

• Concerted regulation of free arachidonic acid and hormone-induced steroid synthesis by acyl-CoA thioesterases and acyl-CoA synthetases in adrenal cells.

  European journal of biochemistry 20021101

• Screening of ubiquitous plant constituents for COX-2 inhibition with a scintillation proximity based assay.

  Journal of natural products 20021101

• Influences of a dietary fatty acid composition on the emergence of glutathione S-transferase-P (GST-P) positive foci in the liver of carcinogen-treated rats.

  Prostaglandins, leukotrienes, and essential fatty acids 20021101

• The molecular mechanisms of allergic diseases: immunoglobulin E dependent and independent signaling pathways converge in eliciting the release of arachidonic acid metabolites.

  The Israel Medical Association journal : IMAJ 20021101

• Doxorubicin increases intracellular diacylglycerol by the mobilization of choline-enriched phospholipids in rat hepatocytes.

  Annals of the New York Academy of Sciences 20021101

• Phospholipase A2 activity in platelets of patients with uremia.

  Platelets 20021101

• Drug-metabolizing cytochrome P450s in the brain.

  Journal of psychiatry & neuroscience : JPN 20021101

• Effect of S-(1,2-dicarboxyethyl) glutathione and S-(1,2-dicarboxyethyl) cysteine on the stimulus-induced superoxide generation and tyrosyl phosphorylation of proteins in human neutrophils.

  Clinical chemistry and laboratory medicine 20021101

• Fatty acid mobilized by the vascular endothelial growth factor in human endothelial cells.

  Lipids 20021101

• Products of 15-lipoxygenase: are they important in asthma?

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20021101

• Uncoupled regulation of leukotriene C4 synthase in platelets from aspirin-intolerant asthmatics and healthy volunteers after aspirin treatment.

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20021101

• Protection by estrogens of biological damage by 2,2'-azobis(2-amidinopropane) dihydrochloride.

  The Journal of steroid biochemistry and molecular biology 20021101

• Phospholipase A(2) regulation of arachidonic acid mobilization.

  FEBS letters 20021030

• Biological effects of group IIA secreted phosholipase A(2).

  FEBS letters 20021030

• Secretory phospholipase A2-mediated neuronal cell death involves glutamate ionotropic receptors.

  Neuroreport 20021028

• Bradykinin increases permeability by calcium and 5-lipoxygenase in the ECV304/C6 cell culture model of the blood-brain barrier.

  Brain research 20021025

• On the interaction of specific prostaglandin H synthase-2 inhibitors with prostaglandin H synthase-1.

  European journal of pharmacology 20021025

• Cathepsin B mediates tumor necrosis factor-induced arachidonic acid release in tumor cells.

  The Journal of biological chemistry 20021018

• Cooperation between secretory phospholipase A2 and TNF-receptor superfamily signaling: implications for the inflammatory response in atherogenesis.

  Circulation research 20021018

• Citicoline mechanisms and clinical efficacy in cerebral ischemia.

  Journal of neuroscience research 20021015

• Epidermal growth factor induces p11 gene and protein expression and down-regulates calcium ionophore-induced arachidonic acid release in human epithelial cells.

  The Journal of biological chemistry 20021011

• Structural characterization of arachidonyl radicals formed by aspirin-treated prostaglandin H synthase-2.

  The Journal of biological chemistry 20021011

• In vitro anti-inflammatory and anti-proliferative activity of sulfolipids from the red alga Porphyridium cruentum.

  Journal of agricultural and food chemistry 20021009

• The role of cyclo-oxygenase 1 and 2 activity in prostaglandin E(2) secretion by cultured human adult microglia: implications for Alzheimer's disease.

  Brain research 20021004

• Isolation and structural elucidation of biologically active phospholipids from Scytonema julianum (cyanobacteria).

  The Biochemical journal 20021001

• Inhibition of arachidonic acid release from human peripheral mononuclear cells by heat shock treatment and geldanamycin.

  Immunology letters 20021001

• Hyperosmotic stress induces phosphorylation of cytosolic phospholipase A(2) in HaCaT cells by an epidermal growth factor receptor-mediated process.

  Cellular signalling 20021001

• Contribution of different phospholipases and arachidonic acid metabolites in the response of gallbladder smooth muscle to cholecystokinin.

  Biochemical pharmacology 20021001

• Decrease in efficacy and potency of nonsteroidal anti-inflammatory drugs by chronic delta(9)-tetrahydrocannabinol administration.

  The Journal of pharmacology and experimental therapeutics 20021001

• Secretory phospholipase A(2) inhibits epidermal growth factor-induced receptor activation.

  Experimental cell research 20021001

• Effect of reduced dietary protein intake on hepatic and plasma essential fatty acid concentrations in the adult female rat: effect of pregnancy and consequences for accumulation of arachidonic and docosahexaenoic acids in fetal liver and brain.

  The British journal of nutrition 20021001

• Red blood cell and plasma phospholipid arachidonic and docosahexaenoic acid levels at birth and cognitive development at 4 years of age.

  Early human development 20021001

• Arachidonic acid plays a role in rat vomeronasal signal transduction.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20021001

• Bovine serum albumin enhances nicotinic acetylcholine receptor function in mouse thalamic synaptosomes.

  Journal of neurochemistry 20021001

• Thiolic antioxidants protect from nitric oxide-induced toxicity in fetal midbrain cultures.

  Neuropharmacology 20021001

• The cyclooxygenase inhibitor ibuprofen and the FLAP inhibitor MK886 inhibit pancreatic carcinogenesis induced in hamsters by transplacental exposure to ethanol and the tobacco carcinogen NNK.

  Journal of cancer research and clinical oncology 20021001

• Asthma: a brief overview.

  The American journal of the medical sciences 20021001

• Mass spectrometric analysis of leukotriene A4 and other chemically reactive metabolites of arachidonic acid.

  Journal of the American Society for Mass Spectrometry 20021001

• Distinct pathways of lipopolysaccharide priming of human neutrophil respiratory burst: role of lipid mediator synthesis and sensitivity to interleukin-10.

  Critical care medicine 20021001

• Blood flow control during exercise: role for the venular endothelium?

  Exercise and sport sciences reviews 20021001

• Polyunsaturated fatty acids in plasma and erythrocyte membrane lipids of diabetic children.

  Prostaglandins, leukotrienes, and essential fatty acids 20021001

• Dietary conjugated linoleic acid with fish oil alters yolk n-3 and trans fatty acid content and volatile compounds in raw, cooked, and irradiated eggs.

  Poultry science 20021001

• Role of PKC and MAPK in cytosolic PLA2 phosphorylation and arachadonic acid release in primary murine astrocytes.

  Journal of neurochemistry 20021001

• [Role of brain prostaglandin biosynthesis in behavioral disorders induced by tetrahydrocannabinol in marihuana].

  Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology 20021001

• Anticancer activity of Scutellaria baicalensis and its potential mechanism.

  Journal of alternative and complementary medicine (New York, N.Y.) 20021001

• Surface expression of fatty acid translocase (FAT/CD36) on platelets in myeloproliferative disorders and non-insulin dependent diabetes mellitus: effect on arachidonic acid uptake.

  Molecular and cellular biochemistry 20021001

• Trans isomeric octadecenoic acids are related inversely to arachidonic acid and DHA and positively related to mead acid in umbilical vessel wall lipids.

  Lipids 20021001

• Effects of arachidonic acid on sodium currents in rat dorsal root ganglion neurons.

  Brain research 20020920

• Inhibition of peroxisome proliferator-activated receptor (PPAR)-mediated keratinocyte differentiation by lipoxygenase inhibitors.

  The Biochemical journal 20020915

• Identification of calcium-independent phospholipase A2 (iPLA2) beta, and not iPLA2gamma, as the mediator of arginine vasopressin-induced arachidonic acid release in A-10 smooth muscle cells. Enantioselective mechanism-based discrimination of mammalian iPLA2s.

  The Journal of biological chemistry 20020906

• Arachidonic acid inhibits K channels in basolateral membrane of the thick ascending limb.

  American journal of physiology. Renal physiology 20020901

• Bradykinin increases IL-8 generation in airway epithelial cells via COX-2-derived prostanoids.

  American journal of physiology. Lung cellular and molecular physiology 20020901

• Calcium-independent phospholipase A(2)-derived arachidonic acid is essential for endothelium-dependent relaxation by acetylcholine.

  The Journal of pharmacology and experimental therapeutics 20020901

• Phase angle and n-3 polyunsaturated fatty acids in sickle cell disease.

  Archives of disease in childhood 20020901

• Arachidonate cascade, apoptosis, and vitamin E in peripheral blood mononuclear cells from hemodialysis patients.

  American journal of kidney diseases : the official journal of the National Kidney Foundation 20020901

• Polycyclic aromatic hydrocarbons present in cigarette smoke cause endothelial cell apoptosis by a phospholipase A2-dependent mechanism.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20020901

• Synaptic precedence during synapse formation between reciprocally connected neurons involves transmitter-receptor interactions and AA metabolites.

  Journal of neurophysiology 20020901

• Modulation of ASIC channels in rat cerebellar Purkinje neurons by ischaemia-related signals.

  The Journal of physiology 20020901

• Celecoxib does not affect the antiplatelet activity of aspirin in healthy volunteers.

  Journal of clinical pharmacology 20020901

• P450-dependent arachidonic acid metabolism and angiotensin II-induced renal damage.

  Hypertension (Dallas, Tex. : 1979) 20020901

• NO synthesis and its regulation in the arachidonic-acid-stimulated rat polymorphonuclear leukocytes.

  Nitric oxide : biology and chemistry 20020901

• Monitoring of morphological development of the arachidonic-acid-producing filamentous microorganism Mortierella alpina.

  Applied microbiology and biotechnology 20020901

• Doxorubicin-dependent reduction of ferrylmyoglobin and inhibition of lipid peroxidation: implications for cardiotoxicity of anticancer anthracyclines.

  Chemical research in toxicology 20020901

• Quantitative high-performance liquid chromatography/electrospray ionization tandem mass spectrometric analysis of 2- and 3-series prostaglandins in cultured tumor cells.

  Analytical biochemistry 20020901

• The simultaneous quantification of cytochrome P450 dependent linoleate and arachidonate metabolites in urine by HPLC-MS/MS.

  Journal of lipid research 20020901

• Cholesterol-dependent modulation of the toxicity of HIV-1 coat protein gp120 in human neuroblastoma cells.

  Journal of neurochemistry 20020901

• Quinoline alkaloids and anti-platelet aggregation constituents from the leaves of Melicope semecarpifolia.

  Planta medica 20020901

• Arachidonic acid and docosahexaenoic acid suppress thrombin-evoked Ca2+ response in rat astrocytes by endogenous arachidonic acid liberation.

  Journal of neurochemistry 20020901

• [ENT inflammation and importance of fenspiride].

  Presse medicale (Paris, France : 1983) 20020901

• Progress in 5H[1]benzopyrano[4,3-d]pyrimidin-5-amine series: 2-methoxy derivatives effective as antiplatelet agents with analgesic activity.

  Farmaco (Societa chimica italiana : 1989) 20020901

• Effects of arachidonic acid on ATP-sensitive K+ current in murine colonic smooth muscle cells.

  Japanese journal of pharmacology 20020901

• Arachidonic acid-derived oxidation products initiate apoptosis in vascular smooth muscle cells.

  Prostaglandins & other lipid mediators 20020901

• Role of contaminating platelets in thromboxane synthesis in primary cultures of human umbilical vein endothelial cells.

  Prostaglandins & other lipid mediators 20020901

• Visual acuity and retinal function in infant monkeys fed long-chain PUFA.

  Lipids 20020901

• Lipoxygenase inhibitors attenuate growth of human pancreatic cancer xenografts and induce apoptosis through the mitochondrial pathway.

  Molecular cancer therapeutics 20020901

• Arachidonic acid cytotoxicity in leukocytes: implications of oxidative stress and eicosanoid synthesis.

  Biology of the cell 20020901

• Mitochondria are direct targets of the lipoxygenase inhibitor MK886. A strategy for cell killing by combined treatment with MK886 and cyclooxygenase inhibitors.

  The Journal of biological chemistry 20020830

• Inhibition of the splicing of glucose-6-phosphate dehydrogenase precursor mRNA by polyunsaturated fatty acids.

  The Journal of biological chemistry 20020823

• Arachidonic acid release and prostaglandin F(2alpha) formation induced by anandamide and capsaicin in PC12 cells.

  European journal of pharmacology 20020823

• Modulation of PGE(2) and TNFalpha by nitric oxide and LPS-activated RAW 264.7 cells.

  Cytokine 20020821

• Pivotal role of superoxides generated in the mitochondrial respiratory chain in peroxynitrite-dependent activation of phospholipase A2.

  The Biochemical journal 20020815

• Inflammation and cancer, the mastocytoma P815 tumor model revisited: triggering of macrophage activation in vivo with pro-tumorigenic consequences.

  International journal of cancer 20020810

• Potent modification of low density lipoprotein by group X secretory phospholipase A2 is linked to macrophage foam cell formation.

  The Journal of biological chemistry 20020809

• Platelet-activating factor increases prostaglandin E(2) release from astrocyte-enriched cortical cell cultures.

  Brain research 20020809

• Involvement of GD3 in platelet activation. A novel association with Fcgamma receptor.

  Biochimica et biophysica acta 20020808

• Sulfur mustard-induced arachidonic acid release is mediated by phospholipase D in human keratinocytes.

  Biochemical and biophysical research communications 20020802

• Antiplatelet aggregation activity of diterpene alkaloids from Spiraea japonica.

  European journal of pharmacology 20020802

• Acid- and bile-induced PGE(2) release and hyperproliferation in Barrett's esophagus are COX-2 and PKC-epsilon dependent.

  American journal of physiology. Gastrointestinal and liver physiology 20020801

• Prostanoids and pain: unraveling mechanisms and revealing therapeutic targets.

  Trends in molecular medicine 20020801

• Renal cytochrome p450 oxygenases and preglomerular vascular response to arachidonic acid and endothelin-1 following ischemia/reperfusion.

  The Journal of pharmacology and experimental therapeutics 20020801

• Extraction of lipids from Mortierella alpina and enrichment of arachidonic acid from the fungal lipids.

  Bioresource technology 20020801

• Short-term regulation of basolateral organic anion uptake in proximal tubular OK cells: EGF acts via MAPK, PLA(2), and COX1.

  Journal of the American Society of Nephrology : JASN 20020801

• [The influence of human milk and various artificial formulae commercially available in Spain on the fatty acid status of infants in the first two months of life].

  Anales espanoles de pediatria 20020801

• Endothelin-1-induced arachidonic acid release by cytosolic phospholipase A2 activation in rat vascular smooth muscle via extracellular signal-regulated kinases pathway.

  Biochemical pharmacology 20020801

• Differential effects of polybrominated diphenyl ethers and polychlorinated biphenyls on [3H]arachidonic acid release in rat cerebellar granule neurons.

  Toxicological sciences : an official journal of the Society of Toxicology 20020801

• Differential effects of arachidonoyl trifluoromethyl ketone on arachidonic acid release and lipid mediator biosynthesis by human neutrophils. Evidence for different arachidonate pools.

  European journal of biochemistry 20020801

• Regulation of an ATP-conductive large-conductance anion channel and swelling-induced ATP release by arachidonic acid.

  The Journal of physiology 20020801

• Cloning and functional characterization of Phaeodactylum tricornutum front-end desaturases involved in eicosapentaenoic acid biosynthesis.

  European journal of biochemistry 20020801

• Disturbances in essential fatty acid metabolism in patients receiving long-term home parenteral nutrition.

  Digestive diseases and sciences 20020801

• Free fatty acids in human cerebrospinal fluid following subarachnoid hemorrhage and their potential role in vasospasm: a preliminary observation.

  Journal of neurosurgery 20020801

• Pharmacology of endothelin receptor antagonists ABT-627, ABT-546, A-182086 and A-192621: in vitro studies.

  Clinical science (London, England : 1979) 20020801

• Effects of alumina and zirconium dioxide particles on arachidonic acid metabolism and proinflammatory interleukin production in osteoarthritis and rheumatoid synovial cells.

  The Journal of bone and joint surgery. British volume 20020801

• Effect of crystal form on in vivo topical anti-inflammatory activity of corticosteroids.

  Archives of pharmacal research 20020801

• Dietary modification of inflammation with lipids.

  The Proceedings of the Nutrition Society 20020801

• Phospholipase A2 enzymes.

  Prostaglandins & other lipid mediators 20020801

• The structures of prostaglandin endoperoxide H synthases-1 and -2.

  Prostaglandins & other lipid mediators 20020801

• Prostaglandins and other lipid mediators in Alzheimer's disease.

  Prostaglandins & other lipid mediators 20020801

• Mammalian arachidonate 15-lipoxygenases structure, function, and biological implications.

  Prostaglandins & other lipid mediators 20020801

• Prostaglandin E synthase.

  Prostaglandins & other lipid mediators 20020801

• Allene oxide synthases and allene oxides.

  Prostaglandins & other lipid mediators 20020801

• Glutathione adducts of oxyeicosanoids.

  Prostaglandins & other lipid mediators 20020801

• The N-terminal domain of the reticulocyte-type 15-lipoxygenase is not essential for enzymatic activity but contains determinants for membrane binding.

  The Journal of biological chemistry 20020726

• Monocyte-derived soluble protein confers 5-lipoxygenase activity Ca2+-dependent.

  Biochemical and biophysical research communications 20020726

• Differential metabolism of dihomo-gamma-linolenic acid and arachidonic acid by cyclo-oxygenase-1 and cyclo-oxygenase-2: implications for cellular synthesis of prostaglandin E1 and prostaglandin E2.

  The Biochemical journal 20020715

• The tautomerase active site of macrophage migration inhibitory factor is a potential target for discovery of novel anti-inflammatory agents.

  The Journal of biological chemistry 20020712

• Cytosolic phospholipase A2 (cPLA2) regulation of human monocyte NADPH oxidase activity. cPLA2 affects translocation but not phosphorylation of p67(phox) and p47(phox).

  The Journal of biological chemistry 20020712

• Natural ligands of PPARgamma: are prostaglandin J(2) derivatives really playing the part?

  Cellular signalling 20020701

• Lipid and fatty acid composition of the green oleaginous alga Parietochloris incisa, the richest plant source of arachidonic acid.

  Phytochemistry 20020701

• Involvement of oxidative stress in bee venom-induced inhibition of Na+/glucose cotransporter in renal proximal tubule cells.

  Clinical and experimental pharmacology & physiology 20020701

• Cytochrome P-450 4A isoform expression and 20-HETE synthesis in renal preglomerular arteries.

  American journal of physiology. Renal physiology 20020701

• Beta-adrenergic and arachidonic acid-mediated growth regulation of human breast cancer cell lines.

  International journal of oncology 20020701

• Role of 20-hydroxyeicosatetraenoic acid in the renal and vasoconstrictor actions of angiotensin II.

  American journal of physiology. Regulatory, integrative and comparative physiology 20020701

• CYP4A mRNA, protein, and product in rat lungs: novel localization in vascular endothelium.

  Journal of applied physiology (Bethesda, Md. : 1985) 20020701

• The S100A8/A9 protein as a partner for the cytosolic factors of NADPH oxidase activation in neutrophils.

  European journal of biochemistry 20020701

• Antioxidant and pro-oxidant effects of a manganese porphyrin complex against CYP2E1-dependent toxicity.

  Free radical biology & medicine 20020701

• Do lithium and anticonvulsants target the brain arachidonic acid cascade in bipolar disorder?

  Archives of general psychiatry 20020701

• Arachidonic acid release and prostaglandin F2alpha formation induced by phenylarsine oxide in PC12 cells: possible involvement of secretory phospholipase A2 activity.

  Biochemical pharmacology 20020701

• Impact of phyto-oxylipins in plant defense.

  Trends in plant science 20020701

• Lack of Fas/CD95 surface expression in highly proliferative leukemic cell lines correlates with loss of CtBP/BARS and redirection of the protein toward giant lysosomal structures.

  Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 20020701

• Liver triacylglycerols and free fatty acids in streptozotocin-induced diabetic rats have atypical n-6 and n-3 pattern.

  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20020701

• Effect of a potent cyclooxygenase inhibitor, 5-ethyl-4-methoxy-2-phenylquinoline (KTC-5), on human platelets.

  The Journal of pharmacy and pharmacology 20020701

• Stereo-isomer specific induction of renal cell apoptosis by synthetic muramyl dipeptide (N-acetylmuramyl-L-alanyl-D-isoglutamine).

  Molecular and cellular biochemistry 20020701

• D-003, a potential antithrombotic compound isolated from sugar cane wax with effects on arachidonic acid metabolites.

  Prostaglandins, leukotrienes, and essential fatty acids 20020701

• The role of cyclooxygenase-2 in the pathogenesis of skin cancer.

  Journal of drugs in dermatology : JDD 20020701

• Transforming growth factor-beta1 regulation of growth zone chondrocytes is mediated by multiple interacting pathways.

  Biochimica et biophysica acta 20020612

• Purification and characterization of a cytosolic, 42-kDa and Ca2+-dependent phospholipase A2 from bovine red blood cells: its involvement in Ca2+-dependent release of arachidonic acid from mammalian red blood cells.

  The Journal of biological chemistry 20020607

• Simple, intuitive calculations of free energy of binding for protein-ligand complexes. 1. Models without explicit constrained water.

  Journal of medicinal chemistry 20020606

• Implication of three isoforms of PLA(2) in human T-cell proliferation.

  FEBS letters 20020605

• Fatty acid profiles and lipid peroxidation of microsomes and mitochondria from liver, heart and brain of Cairina moschata.

  The international journal of biochemistry & cell biology 20020601

• Effect of cerebrocrast on the function of human platelets and release of the arachidonic acid from plasma membrane.

  Cell biochemistry and function 20020601

• Arachidonic acid mediates dual effect of TNF-alpha on Ca2+ transients and contraction of adult rat cardiomyocytes.

  American journal of physiology. Cell physiology 20020601

• The heart of Ciona intestinalis: eicosanoid-generating capacity and the effects of precursor fatty acids and eicosanoids on heart rate.

  The Journal of experimental biology 20020601

• Association of dietary fatty acids with urinary oxalate excretion in calcium oxalate stone-formers in their fourth decade.

  BJU international 20020601

• Platelet-erythrocyte interactions enhance alpha(IIb)beta(3) integrin receptor activation and P-selectin expression during platelet recruitment: down-regulation by aspirin ex vivo.

  Blood 20020601

• Contribution of renal oxygenases to glycerol-induced acute renal failure in the rat.

  Journal of cardiovascular pharmacology 20020601

• Dual function of nonsteroidal anti-inflammatory drugs (NSAIDs): inhibition of cyclooxygenase and induction of NSAID-activated gene.

  The Journal of pharmacology and experimental therapeutics 20020601

• Cyclosporine A protects against arachidonic acid toxicity in rat hepatocytes: role of CYP2E1 and mitochondria.

  Hepatology (Baltimore, Md.) 20020601

• Induction of MnSOD gene by arachidonic acid is mediated by reactive oxygen species and p38 MAPK signaling pathway in human HepG2 hepatoma cells.

  Free radical biology & medicine 20020601

• Protective effect of arachidonic acid on glutamate neurotoxicity in rat retinal ganglion cells.

  Investigative ophthalmology & visual science 20020601

• Differential oxidative modulation of voltage-dependent K+ currents in rat hippocampal neurons.

  Journal of neurophysiology 20020601

• Cytochrome P450 pathways of arachidonic acid metabolism.

  Current opinion in lipidology 20020601

• Group IID heparin-binding secretory phospholipase A(2) is expressed in human colon carcinoma cells and human mast cells and up-regulated in mouse inflammatory tissues.

  European journal of biochemistry 20020601

• Phosphatidylinositide 3-kinase regulates angiotensin II-induced cytosolic phospholipase A2 activity and growth in vascular smooth muscle cells.

  Archives of biochemistry and biophysics 20020601

• Extracellular ATP and UTP activate the protein kinase B/Akt cascade via the P2Y(2) purinoceptor in renal mesangial cells.

  British journal of pharmacology 20020601

• Docosahexaenoic acid potentiates interleukin-1beta induction of nitric oxide synthase through mechanism involving p44/42 MAPK activation in rat vascular smooth muscle cells.

  British journal of pharmacology 20020601

• Arachidonate CYP hydroxylases of kidney contribute to formation of hypertension and maintenance of blood pressure.

  Acta pharmacologica Sinica 20020601

• Evaluation of leukotriene biosynthetic capacity in lung tissues from horses with recurrent airway obstruction.

  American journal of veterinary research 20020601

• Docosahexaenoic acid provides protection from impairment of learning ability in Alzheimer's disease model rats.

  Journal of neurochemistry 20020601

• Altered arachidonic acid biosynthesis and antioxidant protection mechanisms in Schwann cells grown in elevated glucose.

  Journal of neurochemistry 20020601

• Perinatal supply and metabolism of long-chain polyunsaturated fatty acids: importance for the early development of the nervous system.

  Annals of the New York Academy of Sciences 20020601

• Participation of the arachidonic acid cascade pathway in macrophage binding/uptake of oxidized low density lipoprotein.

  Biological & pharmaceutical bulletin 20020601

• Protein kinase Calpha-dependent increase in Ca2+-independent phospholipase A2 in membranes and arachidonic acid liberation in zymosan-stimulated macrophage-like P388D1 cells.

  Biochemical pharmacology 20020601

• Effect of caffeic acid on apical transporters' dysfunction of renal proximal tubule cells under oxidative stress in vitro.

  Planta medica 20020601

• Systematic review of fatty acid composition of plasma phospholipids of venous cord blood in full-term infants.

  European journal of nutrition 20020601

• Glutamate signalling and secretory phospholipase A2 modulate the release of arachidonic acid from neuronal membranes.

  Journal of neuroscience research 20020601

• Antioxidant activity of the methanol fraction of Pluchea indica root extract.

  Phytotherapy research : PTR 20020601

• Evaluation of antilipid peroxidative action of propolis ethanol extract.

  Phytotherapy research : PTR 20020601

• The opposite effects of cyclic AMP-protein kinase a signal transduction pathway on renal cortical and medullary Na+,K+-ATPase activity.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20020601

• Lipids with an emphasis on long-chain polyunsaturated fatty acids.

  Clinics in perinatology 20020601

• Arachidonic acid inhibition of muscarinic receptor-mediated nitric oxide production occurs at the level of calcium mobilization in Chinese hamster ovary cells.

  Neurochemical research 20020601

• Endocytic prolactin routes to the secretory pathway in lactating mammary epithelial cells.

  Biology of the cell 20020601

• alpha 2B-adrenergic receptor activates MAPK via a pathway involving arachidonic acid metabolism, matrix metalloproteinases, and epidermal growth factor receptor transactivation.

  The Journal of biological chemistry 20020531

• Novel bioactive phospholipids: practical total syntheses of products from the oxidation of arachidonic and linoleic esters of 2-lysophosphatidylcholine(1).

  The Journal of organic chemistry 20020531

• Evidence that protein phosphatase 5 functions to negatively modulate the maturation of the Hsp90-dependent heme-regulated eIF2alpha kinase.

  Biochemistry 20020528

• Cellular arachidonate-releasing function and inflammation-associated expression of group IIF secretory phospholipase A2.

  The Journal of biological chemistry 20020524

• Unraveling lipid metabolism with microarrays: effects of arachidonate and docosahexaenoate acid on murine hepatic and hippocampal gene expression.

  Genome biology 20020523

• Importance of C1B domain for lipid messenger-induced targeting of protein kinase C.

  The Journal of biological chemistry 20020517

• 14,15-Epoxyeicosa-5(Z)-enoic acid: a selective epoxyeicosatrienoic acid antagonist that inhibits endothelium-dependent hyperpolarization and relaxation in coronary arteries.

  Circulation research 20020517

• Evaluation of the effects of anti-thromboxane agents in platelet-vessel wall interaction.

  European journal of pharmacology 20020517

• Transcellular biosynthesis contributes to the production of leukotrienes during inflammatory responses in vivo.

  The Journal of clinical investigation 20020515

• Effect of berberine on arachidonic acid metabolism in rabbit platelets and endothelial cells.

  Thrombosis research 20020515

• Transcriptional regulation of cyclooxygenase-1 by histone deacetylase inhibitors in normal human astrocyte cells.

  The Journal of biological chemistry 20020510

• Arachidonic acid increases intracellular calcium in erythrocytes.

  Biochemical and biophysical research communications 20020510

• alpha(2B)-Adrenergic receptors activate MAPK and modulate proliferation of primary cultured proximal tubule cells.

  American journal of physiology. Renal physiology 20020501

• Membrane mediated signaling mechanisms are used differentially by metabolites of vitamin D(3) in musculoskeletal cells.

  Steroids 20020501

• Metabolic labelling of membrane microdomains/rafts in Jurkat cells indicates the presence of glycerophospholipids implicated in signal transduction by the CD3 T-cell receptor.

  The Biochemical journal 20020501

• Characterization of a novel inhibitor of cytosolic phospholipase A2alpha, pyrrophenone.

  The Biochemical journal 20020501

• Significant utilization of dietary arachidonic acid is for brain adrenic acid in baboon neonates.

  Journal of lipid research 20020501

• Regulation of human penile smooth muscle tone by prostanoid receptors.

  British journal of pharmacology 20020501

• Modulation of platelet aggregation by areca nut and betel leaf ingredients: roles of reactive oxygen species and cyclooxygenase.

  Free radical biology & medicine 20020501

• Translational medicine: targetting cyclo-oxygenase isozymes to prevent cancer.

  QJM : monthly journal of the Association of Physicians 20020501

• Regulation of cyclooxygenase activity and progesterone production in the rat corpus luteum by inducible nitric oxide synthase.

  Reproduction (Cambridge, England) 20020501

• Accumulation of arachidonic acid-rich triacylglycerols in the microalga Parietochloris incisa (Trebuxiophyceae, Chlorophyta).

  Phytochemistry 20020501

• Role of Ca(2+)-independent phospholipase A(2) and cyclooxygenase/lipoxygenase pathways in the nitric oxide production by murine macrophages stimulated by lipopolysaccharides.

  Nitric oxide : biology and chemistry 20020501

• Angiotensin 1-9 and 1-7 release in human heart: role of cathepsin A.

  Hypertension (Dallas, Tex. : 1979) 20020501

• Increased expression of gallbladder cholecystokinin: a receptor in prairie dogs fed a high-cholesterol diet and its dissociation with decreased contractility in response to cholecystokinin.

  The Journal of laboratory and clinical medicine 20020501

• Docosahexaenoic acid and arachidonic acid enhance growth with no adverse effects in preterm infants fed formula.

  The Journal of pediatrics 20020501

• Increased superoxide anion production by platelets in hypercholesterolemic patients.

  Thrombosis and haemostasis 20020501

• Arachidonic acid release by cPLA2 may be causally related to NO-induced apoptosis in vascular smooth muscle cells.

  Journal of cellular physiology 20020501

• Group IB secretory phospholipase A2 induces neuronal cell death via apoptosis.

  Journal of neurochemistry 20020501

• Cyclooxygenase, lipoxygenase and tumor angiogenesis.

  Cellular and molecular life sciences : CMLS 20020501

• Cord blood essential fatty acid and alpha-tocopherol in full-term newborns in a Northeast Brazil area.

  International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20020501

• Seafood consumption, the DHA content of mothers' milk and prevalence rates of postpartum depression: a cross-national, ecological analysis.

  Journal of affective disorders 20020501

• Platelet aggregation in different antithrombotic regimens. Possible proaggregant effect of low level oral anticoagulation.

  Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 20020501

• Generation of reactive oxygen species in blood platelets.

  Platelets 20020501

• Identification of potential physiological activators of protein phosphatase 5.

  Biochemistry 20020430

• Arachidonic acid promotes phosphorylation of 5-lipoxygenase at Ser-271 by MAPK-activated protein kinase 2 (MK2).

  The Journal of biological chemistry 20020426

• On the reanalysis of the GISSI-Prevenzione.

  Circulation 20020423

• Intracellular accumulation of mercury enhances P450 CYP1A1 expression and Cl- currents in cultured shark rectal gland cells.

  Life sciences 20020421

• The role of endogenous human Trp4 in regulating carbachol-induced calcium oscillations in HEK-293 cells.

  The Journal of biological chemistry 20020419

• Angiotensin II receptor-independent antiinflammatory and antiaggregatory properties of losartan: role of the active metabolite EXP3179.

  Circulation research 20020419

• Selective cyclooxygenase-1 and -2 inhibitors each increase allergic inflammation and airway hyperresponsiveness in mice.

  American journal of respiratory and critical care medicine 20020415

• The roles of LAT in platelet signaling induced by collagen, TxA2, or ADP.

  Biochemical and biophysical research communications 20020412

• Identification and biochemical characterisation of a protein phosphatase 5 homologue from Plasmodium falciparum.

  Molecular and biochemical parasitology 20020409

• 1alpha,25(OH)2D3 regulates chondrocyte matrix vesicle protein kinase C (PKC) directly via G-protein-dependent mechanisms and indirectly via incorporation of PKC during matrix vesicle biogenesis.

  The Journal of biological chemistry 20020405

• Structural insight into the role of the second intracellular loop of the bradykinin 2 receptor in signaling and internalization.

  Biopolymers 20020405

• Heterotrimeric G-proteins activate Cl- channels through stimulation of a cyclooxygenase-dependent pathway in a model liver cell line.

  The Journal of biological chemistry 20020405

• Arachidonate release and eicosanoid generation by group IIE phospholipase A(2).

  Biochemical and biophysical research communications 20020405

• Aldosterone interaction with epidermal growth factor receptor signaling in MDCK cells.

  American journal of physiology. Renal physiology 20020401

• Role of ADP-ribose in 11,12-EET-induced activation of K(Ca) channels in coronary arterial smooth muscle cells.

  American journal of physiology. Heart and circulatory physiology 20020401

• Role of myocardium and endothelium in coronary vascular smooth muscle responses to hypoxia.

  American journal of physiology. Heart and circulatory physiology 20020401

• 85-kDa cPLA(2) plays a critical role in PPAR-mediated gene transcription in human hepatoma cells.

  American journal of physiology. Gastrointestinal and liver physiology 20020401

• Proteasome implication in phorbol ester- and GnRH-induced selective down-regulation of PKC (alpha, epsilon, zeta) in alpha T(3)-1 and L beta T(2) gonadotrope cell lines.

  Endocrinology 20020401

• Arachidonic acid differentially affects basal and lipopolysaccharide-induced sPLA(2)-IIA expression in alveolar macrophages through NF-kappaB and PPAR-gamma-dependent pathways.

  Molecular pharmacology 20020401

• Cloning of CYP2J2 gene and identification of functional polymorphisms.

  Molecular pharmacology 20020401

• Increased free radical production in hypertension due to increased expression of the NADPH oxidase subunit p22(phox) in lymphoblast cell lines.

  Journal of hypertension 20020401

• Arachidonic acid converts the glutathione depletion-induced apoptosis to necrosis by promoting lipid peroxidation and reducing caspase-3 activity in rat glioma cells.

  Archives of biochemistry and biophysics 20020401

• Fatty acids and cytokine mRNA expression in human osteoblastic cells: a specific effect of arachidonic acid.

  Clinical science (London, England : 1979) 20020401

• Thermal destabilization of ovarian LH/hCG receptors by negatively charged lipids.

  Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20020401

• Expressions of cyclooxygenase-2 and prostaglandin E-receptors in carcinoma of the gallbladder: crucial role of arachidonate metabolism in tumor growth and progression.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20020401

• Effect of diazepam and clonazepam on the function of isolated rat platelet and neutrophil.

  Medical science monitor : international medical journal of experimental and clinical research 20020401

• Effect of homocysteine on arachidonic acid release in human platelets.

  European journal of clinical investigation 20020401

• Saturated triglycerides and fatty acids activate neutrophils depending on carbon chain-length.

  European journal of clinical investigation 20020401

• Inhibition of proliferation of gastric epithelial cells by a cyclooxygenase 2 inhibitor, JTE522, is also mediated by a PGE2-independent pathway.

  Alimentary pharmacology & therapeutics 20020401

• The effect of betel nut extract on cell growth and prostaglandin endoperoxide synthase in human epidermoid carcinoma cells.

  Prostaglandins & other lipid mediators 20020401

• Differential effects of n-3 and n-6 polyunsaturated fatty acids on BRCA1 and BRCA2 gene expression in breast cell lines.

  The British journal of nutrition 20020401

• The protection of long chain polyunsaturated fatty acids by melatonin during nonenzymatic lipid peroxidation of rat liver microsomes.

  Journal of pineal research 20020401

• Role of mitochondrial complexes I and II, reactive oxygen species and arachidonic acid metabolism in deoxycholate-induced apoptosis.

  Cancer letters 20020328

• Internalized group V secretory phospholipase A2 acts on the perinuclear membranes.

  The Journal of biological chemistry 20020315

• Interaction of antibodies to proteinase 3 (classic anti-neutrophil cytoplasmic antibody) with human renal tubular epithelial cells: impact on signaling events and inflammatory mediator generation.

  Journal of immunology (Baltimore, Md. : 1950) 20020315

• Inhibition of inducible prostaglandin E(2) synthase by 15-deoxy-Delta(12,14)-prostaglandin J(2) and polyunsaturated fatty acids.

  Biochemical pharmacology 20020315

• Design and synthesis of a novel and potent series of inhibitors of cytosolic phospholipase A(2) based on a 1,3-disubstituted propan-2-one skeleton.

  Journal of medicinal chemistry 20020314

• Leukotriene B(4) stimulates Rac-ERK cascade to generate reactive oxygen species that mediates chemotaxis.

  The Journal of biological chemistry 20020308

• T-226296: a novel, orally active and selective melanin-concentrating hormone receptor antagonist.

  European journal of pharmacology 20020308

• CX-659S: a novel diaminouracil derivative that has antioxidative and acute anti-inflammatory activities.

  European journal of pharmacology 20020308

• Arachidonate release and c-fos expression in various models of hypoxia and hypoxia-hypoglycemia in retinoic acid differentiated neuroblastoma cells.

  Neurochemistry international 20020301

• Formation of murine macrophage-derived 5-oxo-7-glutathionyl-8,11,14-eicosatrienoic acid (FOG7) is catalyzed by leukotriene C4 synthase.

  The Journal of biological chemistry 20020301

• Lipopolysaccharide-induced release of arachidonic acid and prostaglandins in liver macrophages: regulation by Group IV cytosolic phospholipase A2, but not by Group V and Group IIA secretory phospholipase A2.

  Cellular signalling 20020301

• ERK and p38 MAP kinase are involved in arachidonic acid release induced by H(2)O(2) and PDGF in mesangial cells.

  American journal of physiology. Renal physiology 20020301

• Staphylococcal alpha-toxin provokes neutrophil-dependent cardiac dysfunction: role of ICAM-1 and cys-leukotrienes.

  American journal of physiology. Heart and circulatory physiology 20020301

• Long-chain polyunsaturated fatty acid accretion in brain.

  Current opinion in clinical nutrition and metabolic care 20020301

• Distinct effects of different calcium-mobilizing agents on cell death in NG108-15 neuroblastoma X glioma cells.

  Molecular pharmacology 20020301

• Regulation of arachidonic acid production by intracellular calcium in parathyroid cells: effect of extracellular phosphate.

  Journal of the American Society of Nephrology : JASN 20020301

• Cyclooxygenase-2-issued prostaglandin e(2) enhances the production of endogenous IL-10, which down-regulates dendritic cell functions.

  Journal of immunology (Baltimore, Md. : 1950) 20020301

• Leukotriene B4 production in human mononuclear phagocytes is modulated by interleukin-4-induced 15-lipoxygenase.

  The Journal of pharmacology and experimental therapeutics 20020301

• Arachidonate metabolism in neonates.

  Pediatric research 20020301

• Efficacy of dietary arachidonic acid provided as triglyceride or phospholipid as substrates for brain arachidonic acid accretion in baboon neonates.

  Pediatric research 20020301

• Fatty acid formula supplementation and neuromotor development in rhesus monkey neonates.

  Pediatric research 20020301

• Dietary long-chain polyunsaturated fatty acids minimize dexamethasone-induced reductions in arachidonic acid status but not bone mineral content in piglets.

  Pediatric research 20020301

• Lipopolysaccharide-induced secretory phospholipase A2 activity in pericytes: a possible mechanism for mediating relaxation.

  Microvascular research 20020301

• Hypertonicity suppresses ionophore-induced product formation and translocation of 5-lipoxygenase in human leukocytes.

  Journal of leukocyte biology 20020301

• Involvement of protein kinase C and arachidonic acid pathways in the gonadotropin-releasing hormone regulation of oocyte meiosis and follicular steroidogenesis in the goldfish ovary.

  Biology of reproduction 20020301

• Phospholipase A2.

  Journal of biochemistry 20020301

• Altered water barrier function in epidermal-type fatty acid binding protein-deficient mice.

  The Journal of investigative dermatology 20020301

• Somatostatin (SRIF) modulates distinct signaling pathways in rat pituitary tumor cells; negative coupling of SRIF receptor subtypes 1 and 2 to arachidonic acid release.

  Naunyn-Schmiedeberg's archives of pharmacology 20020301

• Secreted phospholipase A2 potentiates glutamate-induced calcium increase and cell death in primary neuronal cultures.

  Journal of neuroscience research 20020301

• Formation of cyclic deoxyguanosine adducts from omega-3 and omega-6 polyunsaturated fatty acids under oxidative conditions.

  Chemical research in toxicology 20020301

• [Formation and removal of reactive oxygen species, lipid peroxides and free radicals, and their biological effects].

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20020301

• Endothelium-derived hyperpolarizing factor: is there a novel chemical mediator?

  Clinical and experimental pharmacology & physiology 20020301

• [Inhibitors of 5-lipoxygenase].

  Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti 20020301

• Effects of arachidonic acid plus zinc on glucose disposal in genetically diabetic (ob/ob) mice.

  Diabetes, obesity & metabolism 20020301

• Dose-response effect of docosahexaenoic acid ethyl ester on maze behavior and brain fatty acid composition in adult mice.

  International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20020301

• Effects of various reactive oxygen species on the guinea pig trachea and its epithelium.

  Japanese journal of pharmacology 20020301

• Changes in antioxidant status of lung tissue in experimental diabetes in rabbits.

  Clinical biochemistry 20020301

• Long-chain polyunsaturated fatty acids in rat maternal milk, offspring brain and peripheral tissues in essential fatty acid deficiency.

  Clinical chemistry and laboratory medicine 20020301

• The effect of maternal smoking and ethanol on fatty acid transport by the human placenta.

  The British journal of nutrition 20020301

• The effect of conjugated linoleic acid on arachidonic acid metabolism and eicosanoid production in human saphenous vein endothelial cells.

  Biochimica et biophysica acta 20020227

• Interaction between arachidonic acid and cAMP signaling pathways enhances steroidogenesis and StAR gene expression in MA-10 Leydig tumor cells.

  Molecular and cellular endocrinology 20020225

• Reciprocal regulation of capacitative and non-capacitative Ca2+ entry in A7r5 vascular smooth muscle cells: only the latter operates during receptor activation.

  The Biochemical journal 20020215

• Inhibition of mitochondrial calcium-independent phospholipase A2 (iPLA2) attenuates mitochondrial phospholipid loss and is cardioprotective.

  The Biochemical journal 20020215

• Mechanosensitive ion channels in cultured sensory neurons of neonatal rats.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20020215

• Cationic amphiphilic drugs and platelet phospholipase A(2) (cPLA(2)).

  Thrombosis research 20020215

• Lipid rafts are enriched in arachidonic acid and plasmenylethanolamine and their composition is independent of caveolin-1 expression: a quantitative electrospray ionization/mass spectrometric analysis.

  Biochemistry 20020212

• Pharmacological characterization of SC-57461A (3-[methyl[3-[4-(phenylmethyl)phenoxy]propyl]amino]propanoic acid HCl), a potent and selective inhibitor of leukotriene A(4) hydrolase I: in vitro studies.

  The Journal of pharmacology and experimental therapeutics 20020201

• Activation of 5-lipoxygenase by cell stress is calcium independent in human polymorphonuclear leukocytes.

  Blood 20020201

• Arachidonic and linoleic acid metabolism in mouse intestinal tissue: evidence for novel lipoxygenase activity.

  Archives of biochemistry and biophysics 20020201

• Cytosolic phospholipase A2 shows burst kinetics consistent with the slow, reversible formation of a dead-end complex.

  Archives of biochemistry and biophysics 20020201

• FcgammaR receptors activate MAP kinase and up-regulate the cyclooxygenase pathway without increasing arachidonic acid release in monocytic cells.

  European journal of immunology 20020201

• De novo arachidonic acid synthesis in Perkinsus marinus, a protozoan parasite of the eastern oyster Crassostrea virginica.

  Molecular and biochemical parasitology 20020201

• Effect of the enzyme inhibitor, phenylmethylsulfonyl fluoride, on the IOP profiles of topical anandamides.

  Investigative ophthalmology & visual science 20020201

• Nitric oxide and renal and cardiac dysfunction in cirrhosis.

  Clinical science (London, England : 1979) 20020201

• Indomethacin protects permeability barrier from focal segmental glomerulosclerosis serum.

  Kidney international 20020201

• Should we treat concussion pharmacologically? The need for evidence based pharmacological treatment for the concussed athlete.

  British journal of sports medicine 20020201

• Multiple biological effects of inhibitors of arachidonic acid metabolism on human keratinocytes.

  Archives of dermatological research 20020201

• Biosynthesis of arachidonic acid in the oleaginous microalga Parietochloris incisa (Chlorophyceae): radiolabeling studies.

  Lipids 20020201

• Surrogate markers of disease in mastocytosis.

  International archives of allergy and immunology 20020201

• [Effects of NSAIDs on prostaglandin synthesis].

  Nihon rinsho. Japanese journal of clinical medicine 20020201

• Possible mechanisms of aspirin resistance.

  Journal of thrombosis and thrombolysis 20020201

• Lipid status and long-chain polyunsaturated fatty acid concentrations in adults and adolescents with phenylketonuria on phenylalanine-restricted diet.

  Journal of inherited metabolic disease 20020201

• Cord serum lipid and apolipoprotein levels in preterm infants with the neonatal respiratory distress syndrome.

  The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 20020201

• Cellular and molecular pathways of ischemic neuronal death.

  Journal of biochemistry and molecular biology 20020131

• Human monocyte-derived dendritic cells are deficient in prostaglandin E2 production.

  FEBS letters 20020130

• Delta6-, Stearoyl CoA-, and Delta5-desaturase enzymes are expressed in beta-cells and are altered by increases in exogenous PUFA concentrations.

  Biochimica et biophysica acta 20020130

• Tenidap, a novel anti-inflammatory agent, is an opener of the inwardly rectifying K+ channel hKir2.3.

  European journal of pharmacology 20020125

• Identification of the phospholipase A(2) isoforms that contribute to arachidonic acid release in hypoxic endothelial cells: limits of phospholipase A(2) inhibitors.

  Biochemical pharmacology 20020115

• Endogenous anti-inflammatory mediators from arachidonate in human neutrophils.

  Biochemical and biophysical research communications 20020111

• Role of calcium and calcium-activated proteases in CYP2E1-dependent toxicity in HEPG2 cells.

  The Journal of biological chemistry 20020104

• Analysis of fatty acids released by crotoxin in rat brain synaptosomes.

  Toxicon : official journal of the International Society on Toxinology 20020101

• Role of cytochrome P-450 arachidonate metabolites in endothelin signaling in rat proximal tubule.

  American journal of physiology. Renal physiology 20020101

• Involvement of CYP2J2 and CYP4F12 in the metabolism of ebastine in human intestinal microsomes.

  The Journal of pharmacology and experimental therapeutics 20020101

• Genotype predictors of response to asthma medications.

  Current opinion in pulmonary medicine 20020101

• Secretory phospholipases A2 induce cytokine release from blood and synovial fluid monocytes.

  European journal of immunology 20020101

• Inhibition of cyclooxygenase and prostaglandin E2 synthesis by gamma-mangostin, a xanthone derivative in mangosteen, in C6 rat glioma cells.

  Biochemical pharmacology 20020101

• Lipid peroxidation contributes to immune reactions associated with alcoholic liver disease.

  Free radical biology & medicine 20020101

• Oxysterol-induced activation of macrophage NADPH-oxidase enhances cell-mediated oxidation of LDL in the atherosclerotic apolipoprotein E deficient mouse: inhibitory role for vitamin E.

  Atherosclerosis 20020101

• P-450 metabolites of arachidonic acid in the control of cardiovascular function.

  Physiological reviews 20020101

• Cyclooxygenase-2 is expressed by cumulus cells during oocyte maturation in cattle.

  Molecular reproduction and development 20020101

• Bacterial challenge stimulates formation of arachidonic acid metabolites by human keratinocytes and neutrophils in vitro.

  Clinical and diagnostic laboratory immunology 20020101

• Arachidonic acid release from rat Leydig cells: the involvement of G protein, phospholipase A2 and regulation of cAMP production.

  The Journal of endocrinology 20020101

• Stimulation and proliferation of primary rat hepatic stellate cells by cytochrome P450 2E1-derived reactive oxygen species.

  Hepatology (Baltimore, Md.) 20020101

• Effects of oxidative stress and antioxidant treatments on eicosanoid synthesis and lipid peroxidation in long term human umbilical vein endothelial cells culture.

  Prostaglandins & other lipid mediators 20020101

• LTRPC2 Ca2+-permeable channel activated by changes in redox status confers susceptibility to cell death.

  Molecular cell 20020101

• Histamine H3-receptor-mediated [35S]GTP gamma[S] binding: evidence for constitutive activity of the recombinant and native rat and human H3 receptors.

  British journal of pharmacology 20020101

• Different glucocorticoids vary in their genomic and non-genomic mechanism of action in A549 cells.

  British journal of pharmacology 20020101

• A comparative study of the antipyretic effects of indomethacin and dipyrone in rats.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20020101

• Kinetic expression for the oxidation of linoleic and arachidonic acid esters in their mixed system.

  Bioscience, biotechnology, and biochemistry 20020101

• Effects of two preparations of 75-mg extended-release aspirin on platelet aggregation, prostanoids and nitric oxide production in humans.

  European journal of clinical pharmacology 20020101

• Effect of various oestrogens on cell injury and alteration of apical transporters induced by tert-butyl hydroperoxide in renal proximal tubule cells.

  Clinical and experimental pharmacology & physiology 20020101

• Expression and phosphorylation of mammalian small heat shock proteins.

  Progress in molecular and subcellular biology 20020101

• Sows' milk attenuates dexamethasone-induced reductions in liver docosahexaenoic acid.

  Biology of the neonate 20020101

• Arachidonic acid-derived bioactive lipids: their role and the role for their inhibitors in dermatology.

  Journal of cutaneous medicine and surgery 20020101

• Techniques for determining the metabolic pathways of eicosanoids and for evaluating the rate-controlling enzymes.

  Methods in molecular biology (Clifton, N.J.) 20020101

• Inhibition of arachidonic acid cascade attenuates the induction of c-Fos proteins by DOI, 5-HT2A/2C receptor agonist, in the rat cortex.

  Polish journal of pharmacology 20020101

• [Growth-coupled lipid synthesis in Mortierella alpina LPM 301, a producer of arachidonic acid].

  Mikrobiologiia 20020101

• Oxidative stress and altered prostanoid production in the placenta of streptozotocin-induced diabetic rats.

  Reproduction, fertility, and development 20020101

• Antineoplastic properties of arachidonic acid and its metabolites.

  Prostaglandins, leukotrienes, and essential fatty acids 20020101

• Antitumour and pro-apoptotic actions of highly unsaturated fatty acids in glioma.

  Prostaglandins, leukotrienes, and essential fatty acids 20020101

• Specificity of arachidonic acid-induced inhibition of growth and activation of c-jun kinases and p38 mitogen-activated protein kinase in hematopoietic cells.

  Prostaglandins, leukotrienes, and essential fatty acids 20020101

• The role of arachidonic acid in normal and malignant hematopoiesis.

  Prostaglandins, leukotrienes, and essential fatty acids 20020101

• Eicosapentaenoic acid and arachidonic acid: collaboration and not antagonism is the key to biological understanding.

  Prostaglandins, leukotrienes, and essential fatty acids 20020101

• Fatty acid compositions of serum phospholipids of postmenopausal women: a comparison between Greenland Inuit and Canadians before and after supplementation with fish oil.

  Nutrition (Burbank, Los Angeles County, Calif.) 20020101

• Histamine receptors: specific ligands, receptor biochemistry, and signal transduction.

  Clinical allergy and immunology 20020101

• Determination of intracellular reactive oxygen species as function of cell density.

  Methods in enzymology 20020101

• [Significance of prostaglandins in hepatic amebiasis].

  Salud publica de Mexico 20020101

• Effects of dietary flaxseed oil supplementation on equine plasma fatty acid concentrations and whole blood platelet aggregation.

  Journal of veterinary internal medicine 20020101

• Desaturase activities are depleted before and after weaning in liver microsomes of spontaneously hypertensive rats.

  Prostaglandins, leukotrienes, and essential fatty acids 20020101

• Characterization of a new endothelin receptor ligand by in vitro assays.

  Methods in molecular biology (Clifton, N.J.) 20020101

• Similarity in the distribution of F(2)-isoprostanes in the lipid subfractions of atherosclerotic plaque and in vitro oxidised low density lipoprotein.

  Redox report : communications in free radical research 20020101

• Lipopolysaccharide prevents cell death caused by glutathione depletion: possible mechanisms of protection.

  Neuroscience 20020101

• Inhibition of arachidonate metabolism in human epidermoid carcinoma a431 cells overexpressing phospholipid hydroperoxide glutathione peroxidase.

  Journal of biomedical science 20020101

• Effect of different types of feeding on fatty acid composition of erythrocyte membrane lipids in full-term infants.

  Acta paediatrica (Oslo, Norway : 1992) 20020101

• Green tea catechin improves microsomal phospholipase A2 activity and the arachidonic acid cascade system in the kidney of diabetic rats.

  Asia Pacific journal of clinical nutrition 20020101

• Effects of green tea catechin on prostaglandin synthesis of renal glomerular and renal dysfunction in streptozotocin-induced diabetic rats.

  Asia Pacific journal of clinical nutrition 20020101

• Chronic lithium downregulates cyclooxygenase-2 activity and prostaglandin E(2) concentration in rat brain.

  Molecular psychiatry 20020101

• Docosahexaenoic, arachidonic, palmitic, and oleic acids are differentially esterified into phospholipids of frog retina.

  Prostaglandins, leukotrienes, and essential fatty acids 20020101

• Long-term potentiation in aged rats is restored when the age-related decrease in polyunsaturated fatty acid concentration is reversed.

  Prostaglandins, leukotrienes, and essential fatty acids 20020101

• Species variability in platelet aggregation response to different agonists.

  Journal of comparative pathology 20020101

• Effect of glutamate on arachidonic acid production from Mortierella alpina.

  Letters in applied microbiology 20020101

• Effect of nitric oxide on arachidonic acid release from human amnion-like WISH cells.

  Placenta 20020101

• Inhibition of the MEK1/ERK pathway reduces arachidonic acid release independently of cPLA2 phosphorylation and translocation.

  BMC biochemistry 20020101

• [Induced phytophthora resistance in transgenic potato tubers].

  Prikladnaia biokhimiia i mikrobiologiia 20020101

• Regulation of apoptosis through arachidonate cascade in mammalian cells.

  Applied biochemistry and biotechnology 20020101

• Dietary supplementation of long-chain polyunsaturated fatty acids in preterm infants: effects on cerebral maturation.

  Acta paediatrica (Oslo, Norway : 1992) 20020101

• Analysis of the contractile effect of arachidonic acid on rat aorta.

  Proceedings of the Western Pharmacology Society 20020101

• Arachidonic acid mobilization by phospholipase D in the contraction induced by phenylephrine in rat aorta.

  Proceedings of the Western Pharmacology Society 20020101

• Ginsenosides protect apical transporters of cultured proximal tubule cells from dysfunctions induced by h(2)o(2).

  Kidney & blood pressure research 20020101

• Mechanisms sensing and modulating signals arising from cell swelling.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20020101

• Lead-dependent effects on arachidonic acid accumulation and the proliferation of vascular smooth muscle.

  Journal of biochemical and molecular toxicology 20020101

• Regulation of leukotriene synthesis by arachidonic acid in human polymorphonuclear leukocyte adhesive interactions is dependent on the presence of albumin.

  Cell biology international 20020101

• Effect of green tea catechin on arachidonic acid cascade in chronic cadmium-poisoned rats.

  Asia Pacific journal of clinical nutrition 20020101

• Requirement of cyclooxygenase-2 expression and prostaglandins for human prostate cancer cell invasion.

  Clinical & experimental metastasis 20020101

• [Effects of antibodies on contractility of papillary muscle in the rat heart and duration of descending phase of action potential plateau under influence of exogenic arachidonic acid and inhibiting its metabolism].

  Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20020101

• Lipoxygenase inhibitors induce arrest of tumor cells in S-phase of the cell cycle.

  Neoplasma 20020101

• The water-soluble fraction (<10 kD) of bee venom (Apis mellifera) produces inhibitory effect on apical transporters in renal proximal tubule cells.

  Kidney & blood pressure research 20020101

• Structure-activity relationship studies of 1-substituted 3-dodecanoylindole-2-carboxylic acids as inhibitors of cytosolic phospholipase A2-mediated arachidonic acid release in intact platelets.

  Archiv der Pharmazie 20020101

• Subcellular interactions between parallel fibre and climbing fibre signals in Purkinje cells predict sensitivity of classical conditioning to interstimulus interval.

  Integrative physiological and behavioral science : the official journal of the Pavlovian Society 20020101

• Investigation into the involvement of phospholipases A2 and map kinases in modulation of AA release and cell growth in A549 cells.

  Advances in experimental medicine and biology 20020101

• Analysis of cyclooxygenase-substrate interactions using stereospecifically-labeled arachidonic acids.

  Advances in experimental medicine and biology 20020101

• PGG2, 11R-HPETE and 15R/S-HPETE are formed from different conformers of arachidonic acid in the prostaglandin endoperoxide H synthase-1 cyclooxygenase site.

  Advances in experimental medicine and biology 20020101

• 15-lipoxygenase-1 overexpression in prostate adenocarcinoma.

  Advances in experimental medicine and biology 20020101

• Intracellular activation and induction of 12-lipoxygenase in mouse peritoneal macrophages.

  Advances in experimental medicine and biology 20020101

• Determination of cyclooxygenase and arachidonic acid metabolites in invasive human prostate cancer cells.

  Advances in experimental medicine and biology 20020101

• Apoptosis in vascular smooth muscle accompanied by increases in arachidonic acid.

  Advances in experimental medicine and biology 20020101

• Regulation of cell-substrate adhesion by the lipoxygenase and cyclooxygenase branches of arachidonic acid metabolism.

  Advances in experimental medicine and biology 20020101

• Dietary EPA reduces tumor load in ApcMin/+ mice by altering arachidonic acid metabolism, but conjugated linoleic acid, gamma--and alpha-linolenic acids have no effect.

  Advances in experimental medicine and biology 20020101

• Functional assays for identifying ligands at orphan G protein-coupled receptors.

  Receptors & channels 20020101

• An enriched mixture of trans-10,cis-12-CLA inhibits linoleic acid metabolism and PGE2 synthesis in MDA-MB-231 cells.

  Nutrition and cancer 20020101

• Membrane pathology in schizophrenia: implication for arachidonic acid signaling.

  TheScientificWorldJournal 20020101

• Changes of oligosaccharides and fatty acids in monkey hippocampus by synaptic potentiation.

  Neuroreport 20011221

• Activation of ATP-sensitive K(+) channels by epoxyeicosatrienoic acids in rat cardiac ventricular myocytes.

  The Journal of physiology 20011215

• Activation of peroxisome proliferator-activated receptor isoforms and inhibition of prostaglandin H(2) synthases by ibuprofen, naproxen, and indomethacin.

  Biochemical pharmacology 20011215

• Epinephrine--via activation of p38-MAPK--abolishes the effect of aspirin on platelet deposition to collagen.

  Thrombosis research 20011215

• Crystal structures of human serum albumin complexed with monounsaturated and polyunsaturated fatty acids.

  Journal of molecular biology 20011214

• Bcl-2 phosphorylation is required for inhibition of oxidative stress-induced lysosomal leak and ensuing apoptosis.

  FEBS letters 20011214

• A calcium-independent phospholipase activity insensitive to bromoenol lactone mediates arachidonic acid release by lindane in rat myometrial cells.

  Life sciences 20011214

• Preconditioning of 3T3 cells by fresh medium together with genistein enhances prostaglandin E(2) release.

  European journal of pharmacology 20011207

• Effects of arachidonic acid and cyclo (his-pro) on zinc transport across small intestine and muscle tissues.

  Life sciences 20011207

• Antiphospholipid antibodies associated with alcoholic liver disease specifically recognise oxidised phospholipids.

  Gut 20011201

• Ca(2+) influx through nonselective cation channels plays an essential role in noradrenaline-induced arachidonic acid release in Chinese hamster ovary cells expressing alpha(1A)-, alpha(1B)-, or alpha(1D)-adrenergic receptors.

  The Journal of pharmacology and experimental therapeutics 20011201

• Effect of sarsasapogenin and its derivatives on the stimulus coupled responses of human neutrophils.

  Clinica chimica acta; international journal of clinical chemistry 20011201

• Differential regulation of endobiotic-oxidizing cytochromes P450 in vitamin A-deficient male rat liver.

  British journal of pharmacology 20011201

• Arachidonic acid-induced H+ and Ca2+ increases in both the cytoplasm and nucleoplasm of rat cerebellar granule cells.

  The Journal of physiology 20011201

• Cytochrome P450 metabolites of arachidonic acid: novel regulators of renal function.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20011201

• Serum phospholipid fatty acid composition and insulin action in type 2 diabetic patients.

  Metabolism: clinical and experimental 20011201

• Epstein-Barr virus primes human polymorphonuclear leucocytes for the biosynthesis of leukotriene B4.

  Clinical and experimental immunology 20011201

• Chronic nutritional deprivation of n-3 alpha-linolenic acid does not affect n-6 arachidonic acid recycling within brain phospholipids of awake rats.

  Journal of neurochemistry 20011201

• Neurochemical consequences of kainate-induced toxicity in brain: involvement of arachidonic acid release and prevention of toxicity by phospholipase A(2) inhibitors.

  Brain research. Brain research reviews 20011201

• Expression of group IIa secretory phospholipase A2 increases with prostate tumor grade.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20011201

• The transcription factors CREB and c-Fos play key roles in NCAM-mediated neuritogenesis in PC12-E2 cells.

  Journal of neurochemistry 20011201

• Anti-inflammatory activity of a novel selective cyclooxygenase-2 inhibitor, FR140423, on type II collagen-induced arthritis in Lewis rats.

  Prostaglandins & other lipid mediators 20011201

• ATP-induced histamine release is in part related to phospholipase A2-mediated arachidonic acid metabolism in rat peritoneal mast cells.

  Archives of pharmacal research 20011201

• Protective effects of cannabinoid receptor ligands analogous to anandamide against cocaine toxicity.

  Nihon Arukoru Yakubutsu Igakkai zasshi = Japanese journal of alcohol studies & drug dependence 20011201

• Dehydroepiandrosterone alters phospholipid profiles in Zucker rat muscle tissue.

  Lipids 20011201

• Involvement of leukotriene B(4) in substance P-induced itch-associated response in mice.

  The Journal of investigative dermatology 20011201

• Mammalian secreted phospholipases A2 and their pathophysiological significance in inflammatory diseases.

  Current molecular medicine 20011201

• Brucella lipopolysaccharides induce cyclooxygenase-2 expression in monocytic cells.

  Biochemical and biophysical research communications 20011130

• Fatty acid composition of lymphocyte membrane phospholipids in children with acute leukemia.

  Cancer letters 20011128

• Anandamide amidohydrolase activity, released in the medium by Tetrahymena pyriformis. Identification and partial characterization.

  FEBS letters 20011123

• Identification of a new class of molecules, the arachidonyl amino acids, and characterization of one member that inhibits pain.

  The Journal of biological chemistry 20011116

• Ceramide accelerates dephosphorylation of extracellular signal-regulated kinase 1/2 to decrease prostaglandin D(2) production in RBL-2H3 cells.

  Archives of biochemistry and biophysics 20011115

• Liquid chromatographic-electrospray ionization-mass spectrometric analysis of cytochrome P450 metabolites of arachidonic acid.

  Analytical biochemistry 20011115

• Effects of fasting on muscle mitochondrial energetics and fatty acid metabolism in Ucp3(-/-) and wild-type mice.

  American journal of physiology. Endocrinology and metabolism 20011101

• Role of phospholipases A(2) in growth-dependent changes in prostaglandin release from 3T6 fibroblasts.

  Journal of cellular physiology 20011101

• Vicinal nitrohydroxyeicosatrienoic acids: vasodilator lipids formed by reaction of nitrogen dioxide with arachidonic acid.

  The Journal of pharmacology and experimental therapeutics 20011101

• alpha(1)-adrenergic receptors mediate LH-releasing hormone secretion through phospholipases C and A(2) in immortalized hypothalamic neurons.

  Endocrinology 20011101

• 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, a nicotine derivative, induces apoptosis of endothelial cells.

  American journal of physiology. Heart and circulatory physiology 20011101

• Initial and sustained phases of myogenic response of rat mesenteric small arteries.

  American journal of physiology. Heart and circulatory physiology 20011101

• Sulphatides trigger polymorphonuclear granulocyte spreading on collagen-coated surfaces and inhibit subsequent activation of 5-lipoxygenase.

  The Biochemical journal 20011101

• Activation of betagamma subunits of G(i2) and G(i3) proteins by basic secretagogues induces exocytosis through phospholipase Cbeta and arachidonate release through phospholipase Cgamma in mast cells.

  Journal of immunology (Baltimore, Md. : 1950) 20011101

• Role of prostanoids and 20-HETE in mediating oxygen-induced constriction of skeletal muscle resistance arteries.

  Microvascular research 20011101

• Anandamide-induced relaxation of sheep coronary arteries: the role of the vascular endothelium, arachidonic acid metabolites and potassium channels.

  British journal of pharmacology 20011101

• 5-lipoxygenase regulates malignant mesothelial cell survival: involvement of vascular endothelial growth factor.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20011101

• Human airway smooth muscle cells secrete vascular endothelial growth factor: up-regulation by bradykinin via a protein kinase C and prostanoid-dependent mechanism.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20011101

• p38 MAP kinase mediates stress-induced leukotriene synthesis in a human B-lymphocyte cell line.

  Journal of leukocyte biology 20011101

• Biphasic effects of 15-deoxy-delta(12,14)-prostaglandin J(2) on glutathione induction and apoptosis in human endothelial cells.

  Arteriosclerosis, thrombosis, and vascular biology 20011101

• Effects of purified green and black tea polyphenols on cyclooxygenase- and lipoxygenase-dependent metabolism of arachidonic acid in human colon mucosa and colon tumor tissues.

  Biochemical pharmacology 20011101

• Effects of naturally occurring prenylated flavonoids on enzymes metabolizing arachidonic acid: cyclooxygenases and lipoxygenases.

  Biochemical pharmacology 20011101

• Antiapoptotic effect of dipyrone on HL-60, Jurkat and Raji cell lines submitted to UV irradiation, arachidonic acid and cycloheximide treatments.

  International immunopharmacology 20011101

• Increased membrane sphingomyelin and arachidonic acid in stroke-prone spontaneously hypertensive rats.

  American journal of hypertension 20011101

• Anti-thrombosis effect of paeoniflorin: evaluated in a photochemical reaction thrombosis model in vivo.

  Planta medica 20011101

• New insights into the mechanism of action of the anti-inflammatory triterpene lupeol.

  The Journal of pharmacy and pharmacology 20011101

• Innate immune reactions stimulated by a lipopolysaccharide-like component of the alga Prototheca (strain 289).

  Die Naturwissenschaften 20011101

• Arachidonic acid-induced inhibition of Ca2+ channel currents in retinal glial (Müller) cells.

  Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20011101

• Influence of dietary supplementation with long-chain n-3 or n-6 polyunsaturated fatty acids on blood inflammatory cell populations and functions and on plasma soluble adhesion molecules in healthy adults.

  Lipids 20011101

• Lipid remodeling in mouse liver and plasma resulting from delta6 fatty acid desaturase inhibition.

  Lipids 20011101

• Separation and identification of phospholipid peroxidation products.

  Lipids 20011101

• Helicobacter pylori alters n-6 fatty acid metabolism and prostaglandin E2 synthesis in rat gastric mucosal cells.

  Journal of gastroenterology and hepatology 20011101

• Functional interaction of calcium-/calmodulin-dependent protein kinase II and cytosolic phospholipase A(2).

  The Journal of biological chemistry 20011026

• Cytochrome p450 and vascular homeostasis.

  Circulation research 20011026

• Lipoxygenase may be involved in cationic liposome-induced macrophage apoptosis.

  Biochemical and biophysical research communications 20011019

• Acute effects of the cys-leukotriene-1 receptor antagonist, montelukast, on experimental colitis in rats.

  European journal of pharmacology 20011019

• Enhancement of mast cell survival: a novel function of some secretory phospholipase A(2) isotypes.

  Journal of immunology (Baltimore, Md. : 1950) 20011015

• Simultaneous quantification of arachidonic acid metabolites in cultured tumor cells using high-performance liquid chromatography/electrospray ionization tandem mass spectrometry.

  Analytical biochemistry 20011015

• Novel 3-dodecanoylindole-2-carboxylic acid inhibitors of cytosolic phospholipase A(2).

  Bioorganic & medicinal chemistry letters 20011008

• Structure of eicosapentaenoic and linoleic acids in the cyclooxygenase site of prostaglandin endoperoxide H synthase-1.

  The Journal of biological chemistry 20011005

• sPLA(2) cooperates with cPLA(2)alpha to regulate prostacyclin synthesis in human endothelial cells.

  Biochemical and biophysical research communications 20011005

• Clinical and cellular effects of cytochrome P-450 modulators.

  Respiration physiology 20011001

• Inhibitory effects of helenalin and related compounds on 5-lipoxygenase and leukotriene C(4) synthase in human blood cells.

  Biochemical pharmacology 20011001

• Agonist-specific cross talk between ERKs and p38(mapk) regulates PGI(2) synthesis in endothelium.

  American journal of physiology. Cell physiology 20011001

• Endothelium-derived hyperpolarizing factor in coronary microcirculation: responses to arachidonic acid.

  American journal of physiology. Heart and circulatory physiology 20011001

• Superoxide levels and function of cerebral blood vessels after inhibition of CuZn-SOD.

  American journal of physiology. Heart and circulatory physiology 20011001

• Regulation of eosinophil function by phosphatidylinositol-specific PLC and cytosolic PLA(2).

  American journal of physiology. Lung cellular and molecular physiology 20011001

• Identification and localization of five CYP2Cs in murine extrahepatic tissues and their metabolism of arachidonic acid to regio- and stereoselective products.

  The Journal of pharmacology and experimental therapeutics 20011001

• Synergistic toxicity of iron and arachidonic acid in HepG2 cells overexpressing CYP2E1.

  Molecular pharmacology 20011001

• Regulation of cyclo-oxygenase-2.

  Best practice & research. Clinical gastroenterology 20011001

• Suppression of T(3)- and fatty acid-induced membrane permeability transition by L-carnitine.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20011001

• Ethanol- and nicotine-induced membrane changes in embryonic and neonatal chick brains.

  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20011001

• The effect of partial outlet obstruction on prostaglandin generation in the rabbit urinary bladder.

  Prostaglandins & other lipid mediators 20011001

• Calcium influx, arachidonic acid,and control of endothelial cell proliferation.

  Cell calcium 20011001

• Sources of eicosanoid precursor fatty acid pools in tissues.

  Journal of lipid research 20011001

• Arachidonate metabolism and the signaling pathway of induction of apoptosis by oxidized LDL/oxysterol.

  Journal of lipid research 20011001

• Polymorphisms in human CYP2C8 decrease metabolism of the anticancer drug paclitaxel and arachidonic acid.

  Pharmacogenetics 20011001

• [Inflammatory mediators (leukotrienes, thromboxane A2, tachykinins and others)].

  Nihon rinsho. Japanese journal of clinical medicine 20011001

• Comparative study of platelet activation markers in diabetes mellitus patients complicated by cerebrovascular disease.

  Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20011001

• Thiopental enhances human platelet aggregation by increasing arachidonic acid release.

  Canadian journal of physiology and pharmacology 20011001

• Lipid peroxidation and growth inhibition of human microvascular endothelial cells.

  In vitro cellular & developmental biology. Animal 20011001

• Stimulated release of arachidonic acid by agonists of the peroxisome proliferator-activated receptor and retinoic acid receptors.

  Prostaglandins, leukotrienes, and essential fatty acids 20011001

• Modulation of arachidonic acid distribution by conjugated linoleic acid isomers and linoleic acid in MCF-7 and SW480 cancer cells.

  Lipids 20011001

• Concomitant accumulation of intracellular free calcium and arachidonic acid in the ischemic-reperfused rat heart.

  Molecular and cellular biochemistry 20011001

• Docosahexaenoic acid and arachidonic acid in infant development.

  Seminars in neonatology : SN 20011001

• Epoxygenase pathways of arachidonic acid metabolism.

  The Journal of biological chemistry 20010928

• Lysophosphatidic acid activates the 70-kDa S6 kinase via the lipoxygenase pathway.

  Biochemical and biophysical research communications 20010928

• High glucose and advanced glycation end products induce phospholipid hydrolysis and phospholipid enzyme inhibition in bovine retinal pericytes.

  Biochimica et biophysica acta 20010928

• Possible involvement of amino acid transporters on S-nitroso-cysteine-induced inhibition of arachidonic acid release in PC12 cells.

  Neuroscience letters 20010928

• Atypical lambda/iota PKC conveys 5-lipoxygenase/leukotriene B4-mediated cross-talk between phospholipase A2s regulating NF-kappa B activation in response to tumor necrosis factor-alpha and interleukin-1beta.

  The Journal of biological chemistry 20010921

• Reciprocal regulation of capacitative and arachidonate-regulated noncapacitative Ca2+ entry pathways.

  The Journal of biological chemistry 20010921

• Stereospecific synthesis of trans-arachidonic acids.

  Bioorganic & medicinal chemistry letters 20010917

• Phosphorylation of the leucocyte NADPH oxidase subunit p47(phox) by casein kinase 2: conformation-dependent phosphorylation and modulation of oxidase activity.

  The Biochemical journal 20010915

• Calcium-independent phospholipase A(2) is required for human monocyte chemotaxis to monocyte chemoattractant protein 1.

  Journal of immunology (Baltimore, Md. : 1950) 20010915

• Involvement of the 5-lipoxygenase pathway in the neurotoxicity of the prion peptide PrP106-126.

  Journal of neuroscience research 20010915

• tert-Butyl hydroperoxide-induced lipid signaling in hepatocytes: involvement of glutathione and free radicals.

  Biochemical pharmacology 20010915

• Expressed CYP4A4 metabolism of prostaglandin E(1) and arachidonic acid.

  Archives of biochemistry and biophysics 20010915

• Activation of NADPH oxidase-related proton and electron currents in human eosinophils by arachidonic acid.

  The Journal of physiology 20010915

• Coupling between cyclooxygenase, terminal prostanoid synthase, and phospholipase A2.

  The Journal of biological chemistry 20010914

• Hypothalamic 11,12-epoxyeicosatrienoic acid attenuates fever induced by central interleukin-1beta in the rat.

  Neuroscience letters 20010914

• Integrins regulate the intracellular distribution of eukaryotic initiation factor 4E in platelets. A checkpoint for translational control.

  The Journal of biological chemistry 20010907

• Identification of amino acids in the tetratricopeptide repeat and C-terminal domains of protein phosphatase 5 involved in autoinhibition and lipid activation.

  Biochemistry 20010904

• Physiological implications of the contrasting modulation of the activities of the epsilon- and zeta-isoforms of diacylglycerol kinase.

  Biochemistry 20010904

• Five-lipoxygenase inhibitors can mediate apoptosis in human breast cancer cell lines through complex eicosanoid interactions.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010901

• Effect of three flavonoids, 5,7,3',4'-tetrahydroxy-3-methoxy flavone, luteolin, and quercetin, on the stimulus-induced superoxide generation and tyrosyl phosphorylation of proteins in human neutrophil.

  Archives of biochemistry and biophysics 20010901

• Inhibition of adenylylcyclase activity in mouse cerebellum membranes upon hydrolysis of triacylglycerols by triacylglycerol lipase, but not phospholipids by phospholipase A(2).

  Archives of biochemistry and biophysics 20010901

• Cyclooxygenase-2 downregulates inducible nitric oxide synthase in rat intestinal epithelial cells.

  American journal of physiology. Gastrointestinal and liver physiology 20010901

• 12(S)-Hydroperoxy-eicosatetraenoic acid increases arachidonic acid availability in collagen-primed platelets.

  Journal of lipid research 20010901

• Cytochrome c: which way out?

  Hepatology (Baltimore, Md.) 20010901

• Phospholipase A(2) in rabbit tears: a host defense against Staphylococcus aureus.

  Investigative ophthalmology & visual science 20010901

• Fatty acid absorption in preterms on formulas with and without long-chain polyunsaturated fatty acids and in terms on formulas without these added.

  European journal of clinical nutrition 20010901

• Increased tissue concentrations of arachidonic acid in umbilical artery and placenta in fetal growth retardation.

  Acta obstetricia et gynecologica Scandinavica 20010901

• Effect of shigatoxin-1 on arachidonic acid release by human glomerular epithelial cells.

  Kidney international 20010901

• Glomerular epithelial cell arachidonate metabolism in Shiga toxin hemolytic uremic syndrome.

  Kidney international 20010901

• Angiotensin II activates Akt/protein kinase B by an arachidonic acid/redox-dependent pathway and independent of phosphoinositide 3-kinase.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010901

• Eicosanoids act in nodulation reactions to bacterial infections in newly emerged adult honey bees, Apis mellifera, but not in older foragers.

  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20010901

• Decreased arachidonic acid release in peripheral blood monocytes of patients with systemic lupus erythematosus.

  The Journal of rheumatology 20010901

• Gingerols and related analogues inhibit arachidonic acid-induced human platelet serotonin release and aggregation.

  Thrombosis research 20010901

• Differential activation of phospholipases by mitogenic EGF and neurogenic PDGF in immortalized hippocampal stem cell lines.

  Journal of neurochemistry 20010901

• Metabolic characterization of sciadonic acid (5c,11c,14c-eicosatrienoic acid) as an effective substitute for arachidonate of phosphatidylinositol.

  European journal of biochemistry 20010901

• RNA-editing of the 5-HT(2C) receptor alters agonist-receptor-effector coupling specificity.

  British journal of pharmacology 20010901

• Arterial balloon catheter: a new atraumatic device for dilating arterial grafts.

  The Annals of thoracic surgery 20010901

• Angiotensin II type AT(2) receptor mRNA expression and renal vasodilatation are increased in renal failure.

  Hypertension (Dallas, Tex. : 1979) 20010901

• Quinoline alkaloids and other constituents of Melicope semecarpifolia with antiplatelet aggregation activity.

  Journal of natural products 20010901

• Involvement of cytochrome P450 metabolites in the vascular action of angiotensin II on the afferent arterioles.

  Hypertension research : official journal of the Japanese Society of Hypertension 20010901

• Polyunsaturated fatty acids, inflammation, and immunity.

  Lipids 20010901

• Increased synthesis of thromboxane A(2) and expression of procoagulant activity by monocytes in response to arachidonic acid in diabetes mellitus.

  Prostaglandins, leukotrienes, and essential fatty acids 20010901

• Identification of a tyrosine kinase-phosphorylated protein in arachidonic acid- and prostaglandin A(2)-treated cells in vitro.

  Prostaglandins, leukotrienes, and essential fatty acids 20010901

• Phospholipid fatty acids and neurotoxicity in human neuroblastoma SH-SY5Y cells.

  Neuroscience letters 20010831

• Modulation of in vitro platelet 5-HT release by species of Erythrina and Cymbopogon.

  Life sciences 20010831

• Soybean lipoxygenase-1 oxygenates synthetic polyenoic fatty acids with an altered positional specificity: evidence for inverse substrate alignment.

  Biochemistry 20010828

• A TREK-1-like potassium channel in atrial cells inhibited by beta-adrenergic stimulation and activated by volatile anesthetics.

  Circulation research 20010817

• Interactions between apolipoprotein E gene and dietary alpha-tocopherol influence cerebral oxidative damage in aged mice.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20010815

• Role of Ca2+-independent phospholipase A2 on arachidonic acid release induced by reactive oxygen species.

  Archives of biochemistry and biophysics 20010815

• Inhibition of cyclooxygenase-2 aggravates doxorubicin-mediated cardiac injury in vivo.

  The Journal of clinical investigation 20010815

• Plasma nonesterified fatty acid concentration as a risk factor for sudden cardiac death: the Paris Prospective Study.

  Circulation 20010814

• Effects of selective cyclooxygenase-2 inhibition on vascular responses and thrombosis in canine coronary arteries.

  Circulation 20010814

• Serum cholesterol and haemorrhagic stroke.

  Lancet (London, England) 20010811

• Intracellular calcium signals regulating cytosolic phospholipase A2 translocation to internal membranes.

  The Journal of biological chemistry 20010810

• Functional coupling between secretory and cytosolic phospholipase A2 modulates tumor necrosis factor-alpha- and interleukin-1beta-induced NF-kappa B activation.

  The Journal of biological chemistry 20010810

• Amino acid determinants in cyclooxygenase-2 oxygenation of the endocannabinoid 2-arachidonylglycerol.

  The Journal of biological chemistry 20010810

• A pyrrolidine-based specific inhibitor of cytosolic phospholipase A(2)alpha blocks arachidonic acid release in a variety of mammalian cells.

  Biochimica et biophysica acta 20010806

• Inhibition of salivary secretion by lipopolysaccharide: possible role of prostaglandins.

  American journal of physiology. Endocrinology and metabolism 20010801

• Overexpression of cytochrome P450 CYP2J2 protects against hypoxia-reoxygenation injury in cultured bovine aortic endothelial cells.

  Molecular pharmacology 20010801

• Saturated FFAs, palmitic acid and stearic acid, induce apoptosis in human granulosa cells.

  Endocrinology 20010801

• Increase in class 2 aldehyde dehydrogenase expression by arachidonic acid in rat hepatoma cells.

  The Biochemical journal 20010801

• Platelet-derived growth factor stimulates phospholipase C-gamma 1, extracellular signal-regulated kinase, and arachidonic acid release in rat myometrial cells: contribution to cyclic 3',5'-adenosine monophosphate production and effect on cell proliferation.

  Biology of reproduction 20010801

• Esophageal adenocarcinoma: a review and perspectives on the mechanism of carcinogenesis and chemoprevention.

  Carcinogenesis 20010801

• Platelet storage pool deficiency of alpha and delta granules.

  Archives of pathology & laboratory medicine 20010801

• Stimulation of leptin release by arachidonic acid and prostaglandin E(2) in adipose tissue from obese humans.

  Metabolism: clinical and experimental 20010801

• Glucocorticoid receptors are required for up-regulation of neuronal 5-lipoxygenase (5LOX) expression by dexamethasone.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010801

• Effects of arachidonic and docosahexaenoic acids on secretion and degradation of bile salt-dependent lipase in AR4-2J cells.

  Journal of lipid research 20010801

• Growth and development in preterm infants fed long-chain polyunsaturated fatty acids: a prospective, randomized controlled trial.

  Pediatrics 20010801

• Growth and development in term infants fed long-chain polyunsaturated fatty acids: a double-masked, randomized, parallel, prospective, multivariate study.

  Pediatrics 20010801

• Functional and cellular interactions between nitric oxide and prostacyclin.

  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20010801

• High level of alpha2-adrenoceptor in rat foetal liver and placenta is due to alpha2B-subtype expression in haematopoietic cells of the erythrocyte lineage.

  British journal of pharmacology 20010801

• Effect of ethanol on polyunsaturated fatty acid biosynthesis in hepatocytes from spontaneously hypertensive rats.

  Alcoholism, clinical and experimental research 20010801

• Rutaecarpine, a quinazolinocarboline alkaloid, inhibits prostaglandin production in RAW264.7 macrophages.

  Planta medica 20010801

• Alterations of lipoxygenase specificity by targeted substrate modification and site-directed mutagenesis.

  Chemistry & biology 20010801

• Effect of arachidonic acid on duodenal enterocyte ATPases.

  Prostaglandins & other lipid mediators 20010801

• The enhancement of glucose uptake caused by the collapse of gap junction communication is due to an increase in astrocyte proliferation.

  Journal of neurochemistry 20010801

• Lipoxygenases and their involvement in programmed cell death.

  Cell death and differentiation 20010801

• Regulation of prostaglandin synthesis in the human uterus.

  The Journal of maternal-fetal medicine 20010801

• Agglomerates of ultrafine particles of elemental carbon and TiO2 induce generation of lipid mediators in alveolar macrophages.

  Environmental health perspectives 20010801

• Activity of a novel dual thromboxane A(2)receptor antagonist and thromboxane synthase inhibitor (BM-573) on platelet function and isolated smooth muscles.

  Prostaglandins, leukotrienes, and essential fatty acids 20010801

• Polyunsaturated fatty acid deficiency during dietary treatment of very long-chain acyl-CoA dehydrogenase deficiency. Rescue with soybean oil.

  Journal of inherited metabolic disease 20010801

• Menopause-induced changes in lipid fractions and total fatty acids in plasma.

  Endocrine research 20010801

• Effects of phospholipase A(2) activating peptides upon GTP-binding protein-evoked adrenocorticotrophin secretion.

  European journal of pharmacology 20010727

• Activation of the phosphatidylinositol 3-kinase-Akt/protein kinase B signaling pathway in arachidonic acid-stimulated human myeloid and endothelial cells: involvement of the ErbB receptor family.

  The Journal of biological chemistry 20010720

• A new method for the generation of patterned protein films by encapsulation in arrays of thermally evaporated lipids.

  Biotechnology and bioengineering 20010720

• The CYP P450 arachidonic acid monooxygenases: from cell signaling to blood pressure regulation.

  Biochemical and biophysical research communications 20010720

• Inhibition of prostaglandin synthesis by nitric oxide in RAW 264.7 macrophages.

  Archives of biochemistry and biophysics 20010715

• Inhibitors of arachidonic acid metabolism potentiate tumour necrosis factor-alpha-induced apoptosis in HL-60 cells.

  European journal of pharmacology 20010713

• Cytochrome P450 CYP2J9, a new mouse arachidonic acid omega-1 hydroxylase predominantly expressed in brain.

  The Journal of biological chemistry 20010706

• Protein kinases C translocation responses to low concentrations of arachidonic acid.

  The Journal of biological chemistry 20010706

• Arachidonate dilates basilar artery by lipoxygenase-dependent mechanism and activation of K(+) channels.

  American journal of physiology. Regulatory, integrative and comparative physiology 20010701

• Activation of cardiac afferents by arachidonic acid: relative contributions of metabolic pathways.

  American journal of physiology. Heart and circulatory physiology 20010701

• Mechanisms of endocannabinoid inactivation: biochemistry and pharmacology.

  The Journal of pharmacology and experimental therapeutics 20010701

• Role of mitogen-activated protein kinase-mediated cytosolic phospholipase A2 activation in arachidonic acid metabolism in human eosinophils.

  Journal of immunology (Baltimore, Md. : 1950) 20010701

• Gi-mediated activation of the Syk kinase by the receptor mimetic basic secretagogues of mast cells: role in mediating arachidonic acid/metabolites release.

  Journal of immunology (Baltimore, Md. : 1950) 20010701

• Role of prostaglandins in the suppression of apoptosis in hen granulosa cells by transforming growth factor alpha.

  Reproduction (Cambridge, England) 20010701

• Lipid and fatty acid analysis of fresh and frozen-thawed immature and in vitro matured bovine oocytes.

  Reproduction (Cambridge, England) 20010701

• Generation of 8-epi-prostaglandin F(2alpha) in isolated rat kidney glomeruli by a radical-independent mechanism.

  British journal of pharmacology 20010701

• Two types of K+ currents modulated by arachidonic acid in bovine corneal epithelial cells.

  Investigative ophthalmology & visual science 20010701

• Niflumic acid modulates uncoupled substrate-gated conductances in the human glutamate transporter EAAT4.

  The Journal of physiology 20010701

• Localization, anchoring, and functions of protein kinase C isozymes in the heart.

  Journal of molecular and cellular cardiology 20010701

• Individual dosing of ASA prophylaxis by controlling platelet aggregation.

  Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20010701

• Electrospray ionization and tandem mass spectrometry of cysteinyl eicosanoids: leukotriene C4 and FOG7.

  Journal of the American Society for Mass Spectrometry 20010701

• Actions of arachidonic acid on contractions and associated electrical activity in guinea-pig isolated ventricular myocytes.

  Experimental physiology 20010701

• Increased expression of cytosolic phospholipase A2, 5-lipoxygenase and 5-lipoxygenase-activating protein in rat peritoneal macrophages during ovalbumin-induced sensitization.

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20010701

• Antiinflamatory agents less dangerous for gastrointestinal tract.

  Current pharmaceutical design 20010701

• Plasma fatty acid levels in autistic children.

  Prostaglandins, leukotrienes, and essential fatty acids 20010701

• Stimulated release of arachidonic acid from rat liver cells by celecoxib and indomethacin.

  Prostaglandins, leukotrienes, and essential fatty acids 20010701

• Anti-inflammatory and anti-allergic actions by oral administration of a perilla leaf extract in mice.

  Bioscience, biotechnology, and biochemistry 20010701

• Studies of phospholipid metabolism, proliferation, and secretion of stably transfected insulinoma cells that overexpress group VIA phospholipase A2.

  Lipids 20010701

• Incorporation of alpha-linolenic acid and linoleic acid into human respiratory epithelial cell lines.

  Lipids 20010701

• Quantification of key odorants formed by autoxidation of arachidonic acid using isotope dilution assay.

  Lipids 20010701

• Alterations in lipoxygenase and cyclooxygenase-2 catalytic activity and mRNA expression in prostate carcinoma.

  Neoplasia (New York, N.Y.) 20010701

• Effects of liposomes of different phospholipid composition on the induction of respiratory burst in human blood monocytes and alveolar macrophages.

  Membrane & cell biology 20010701

• A new pathway for glucose-dependent insulinotropic polypeptide (GIP) receptor signaling: evidence for the involvement of phospholipase A2 in GIP-stimulated insulin secretion.

  The Journal of biological chemistry 20010629

• Secretory phospholipase A2 mediates cooperative prostaglandin generation by growth factor and cytokine independently of preceding cytosolic phospholipase A2 expression in rat gastric epithelial cells.

  The Journal of biological chemistry 20010615

• Permeation of monovalent cations through the non-capacitative arachidonate-regulated Ca2+ channels in HEK293 cells. Comparison with endogenous store-operated channels.

  The Journal of biological chemistry 20010615

• Cytosolic phospholipase A2 participates with TNF-alpha in the induction of apoptosis of human macrophages infected with Mycobacterium tuberculosis H37Ra.

  Journal of immunology (Baltimore, Md. : 1950) 20010615

• Kinetic modulation of Kv4-mediated A-current by arachidonic acid is dependent on potassium channel interacting proteins.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20010615

• Increased prostacyclin synthesis by atherosclerotic arteries from estrogen-treated monkeys.

  Life sciences 20010615

• Neuroprotective effects of lipoxygenase inhibitors against ischemic injury in rat hippocampal slice cultures.

  Brain research 20010615

• Characterization of the lysyl adducts of prostaglandin H-synthases that are derived from oxygenation of arachidonic acid.

  Biochemistry 20010612

• Mutual antagonism of calcium entry by capacitative and arachidonic acid-mediated calcium entry pathways.

  The Journal of biological chemistry 20010608

• Synthesis and pharmacological evaluation of 2,5-cycloamino-5H-[1]benzopyrano[4,3-d]pyrimidines endowed with in vitro antiplatelet activity.

  Bioorganic & medicinal chemistry letters 20010604

• Stimulation of DNA synthesis by tumor promoters in primary rat hepatocytes is not mediated by arachidonic acid metabolites.

  Journal of cellular physiology 20010601

• Isoprostanes: an overview and putative roles in pulmonary pathophysiology.

  American journal of physiology. Lung cellular and molecular physiology 20010601

• Interleukin-6 family cytokines: signaling and effects in human airway smooth muscle cells.

  American journal of physiology. Lung cellular and molecular physiology 20010601

• Prologue: EDHF--what is it?

  American journal of physiology. Heart and circulatory physiology 20010601

• ATP-mediated release of arachidonic acid metabolites from venular endothelium causes arteriolar dilation.

  American journal of physiology. Heart and circulatory physiology 20010601

• Vasopressin-stimulated Ca2+ spiking in vascular smooth muscle cells involves phospholipase D.

  American journal of physiology. Heart and circulatory physiology 20010601

• Cytochrome P-450 metabolite of arachidonic acid mediates bradykinin-induced negative inotropic effect.

  American journal of physiology. Heart and circulatory physiology 20010601

• Mechanisms of regulation of agonist efficacy at the 5-HT(1A) receptor by phospholipid-derived signaling components.

  The Journal of pharmacology and experimental therapeutics 20010601

• Exacerbation of neuronal cell death by activation of group I metabotropic glutamate receptors: role of NMDA receptors and arachidonic acid release.

  Experimental neurology 20010601

• Stimulation of protease activated receptors on RT4 cells mediates arachidonic acid release via Ca2+ independent phospholipase A2.

  The Journal of urology 20010601

• Arachidonic acid directly activates members of the mitogen-activated protein kinase superfamily in rabbit proximal tubule cells.

  Kidney international 20010601

• Induction of plant gp91 phox homolog by fungal cell wall, arachidonic acid, and salicylic acid in potato.

  Molecular plant-microbe interactions : MPMI 20010601

• Arachidonic acid as a bioactive molecule.

  The Journal of clinical investigation 20010601

• Leukotriene metabolism by intrapulmonary vessels of newborn lambs: effect of platelet-activating factor.

  Experimental lung research 20010601

• Identification of potent odorants formed by autoxidation of arachidonic acid: structure elucidation and synthesis of (E,Z,Z)-2,4,7-tridecatrienal.

  Journal of agricultural and food chemistry 20010601

• Abnormal pressure-natriuresis in hypertension: role of cytochrome P450 metabolites of arachidonic acid.

  American journal of hypertension 20010601

• Involvement of inducible isoforms of COX and NOS in streptozotocin-pancreatic damage in the rat: interactions between nitridergic and prostanoid pathway.

  Prostaglandins, leukotrienes, and essential fatty acids 20010601

• Arachidonic acid and its metabolites are involved in the expression of neocortical spike-and-wave spindling episodes in DBA/2J mice.

  The Journal of pharmacy and pharmacology 20010601

• Characterization of a partial prostaglandin endoperoxide H synthase-1 deficiency in a patient with a bleeding disorder.

  British journal of haematology 20010601

• Inhibition of prostaglandin E2 production by platycodin D isolated from the root of Platycodon grandiflorum.

  Planta medica 20010601

• The analysis of nonsteroidal antiinflammatory drug selectivity in prostaglandin G/H synthase (PGHS)-null cells.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20010601

• Influence of formulas with borage oil or borage oil plus fish oil on the arachidonic acid status in premature infants.

  Lipids 20010601

• Effects of delta5 polyunsaturated fatty acids of maritime pine (Pinus pinaster) seed oil on the fatty acid profile of the developing brain of rats.

  Lipids 20010601

• Real-time measurement of intracellular reactive oxygen species using Mito tracker orange (CMH2TMRos).

  Bioscience reports 20010601

• Anti-CD3 and concanavalin A-induced human T cell proliferation is associated with an increased rate of arachidonate-phospholipid remodeling. Lack of involvement of group IV and group VI phospholipase A2 in remodeling and increased susceptibility of proliferating T cells to CoA-independent transacyclase inhibitor-induced apoptosis.

  The Journal of biological chemistry 20010518

• Amyloid precursor protein and amyloid beta peptide in human platelets. Role of cyclooxygenase and protein kinase C.

  The Journal of biological chemistry 20010518

• Arachidonic acid modulates the spatiotemporal characteristics of agonist-evoked Ca2+ waves in mouse pancreatic acinar cells.

  The Journal of biological chemistry 20010518

• Feedback control of the arachidonate cascade in rheumatoid synoviocytes by 15-deoxy-Delta(12,14)-prostaglandin J2.

  Biochemical and biophysical research communications 20010518

• Human tear lipocalin acts as an oxidative-stress-induced scavenger of potentially harmful lipid peroxidation products in a cell culture system.

  The Biochemical journal 20010515

• Increased release of arachidonic acid and eicosanoids in iron-overloaded cardiomyocytes.

  Circulation 20010515

• Identification and quantitation of unique fatty acid oxidation products in human atherosclerotic plaque using high-performance liquid chromatography.

  Analytical biochemistry 20010515

• Clinical concentrations of doxorubicin inhibit activity of myocardial membrane-associated, calcium-independent phospholipase A(2).

  Cancer research 20010515

• Amyloid beta(1-42) and its beta(25-35) fragment induce in vitro phosphatidylcholine hydrolysis in bovine retina capillary pericytes.

  Neuroscience letters 20010511

• Role of brain arachidonic acid cascade on central CRF1 receptor-mediated activation of sympatho-adrenomedullary outflow in rats.

  European journal of pharmacology 20010511

• A long-lasting facilitation of hippocampal neurotransmission via a phospholipase A2 signaling pathway.

  Life sciences 20010511

• Absence of 12/15-lipoxygenase expression decreases lipid peroxidation and atherogenesis in apolipoprotein e-deficient mice.

  Circulation 20010508

• Mammalian phospholipases A(2): mediators of inflammation, proliferation and apoptosis.

  Progress in lipid research 20010501

• Plasmalogens: biosynthesis and functions.

  Progress in lipid research 20010501

• Arachidonic acid both inhibits and enhances whole cell calcium currents in rat sympathetic neurons.

  American journal of physiology. Cell physiology 20010501

• Arachidonic acid reversibly enhances N-type calcium current at an extracellular site.

  American journal of physiology. Cell physiology 20010501

• Dual signaling by the alpha(v)beta(3)-integrin activates cytosolic PLA(2) in bovine pulmonary artery endothelial cells.

  American journal of physiology. Lung cellular and molecular physiology 20010501

• Cytochrome P450 metabolites of arachidonic acid but not cyclooxygenase-2 metabolites contribute to the pulmonary vascular hyporeactivity in rats with acute Pseudomonas pneumonia.

  The Journal of pharmacology and experimental therapeutics 20010501

• Direct activation of an inwardly rectifying potassium channel by arachidonic acid.

  Molecular pharmacology 20010501

• Effects of prostaglandin F(2alpha)and carbachol on MAP kinases, cytosolic phospholipase A(2)and arachidonic acid release in cat iris sphincter smooth muscle cells.

  Experimental eye research 20010501

• A redox-based mechanism for the contractile and relaxing effects of NO in the guinea-pig gall bladder.

  The Journal of physiology 20010501

• Changes in mitochondrial and microsomal lipid peroxidation and fatty acid profiles in adrenal glands, testes, and livers from alpha-tocopherol-deficient rats.

  Free radical biology & medicine 20010501

• Determination of cytochrome P450 metabolites of arachidonic acid in coronary venous plasma during ischemia and reperfusion in dogs.

  Analytical biochemistry 20010501

• Prolactin signalling to milk protein secretion but not to gene expression depends on the integrity of the Golgi region.

  Journal of cell science 20010501

• Chronic valproate treatment decreases the in vivo turnover of arachidonic acid in brain phospholipids: a possible common effect of mood stabilizers.

  Journal of neurochemistry 20010501

• Transfection of annexin 1 in monocytic cells produces a high degree of spontaneous and stimulated apoptosis associated with caspase-3 activation.

  British journal of pharmacology 20010501

• Delivery and turnover of plasma-derived essential PUFAs in mammalian brain.

  Journal of lipid research 20010501

• Modulation of cytosolic phospholipase A(2) by PPAR activators in human preadipocytes.

  Journal of lipid research 20010501

• Conjugated linoleic acid and oxidative behaviour in cancer cells.

  Biochemical Society transactions 20010501

• Age-dependent decrease in adenosine A1 receptor binding sites in the rat brain. Effect of cis unsaturated free fatty acids.

  European journal of biochemistry 20010501

• Free-radical-induced oxidation of arachidonoyl plasmalogen phospholipids: antioxidant mechanism and precursor pathway for bioactive eicosanoids.

  Chemical research in toxicology 20010501

• Involvement of MAP kinases in the control of cPLA(2) and arachidonic acid release in endothelial cells.

  Atherosclerosis 20010501

• Effect of gamma-hydroxybutyric acid on human platelet aggregation in vitro.

  Thrombosis research 20010501

• Melittin exerts multiple effects on the release of free fatty acids from L1210 cells: lack of selective activation of phospholipase A2 by melittin.

  Archives of biochemistry and biophysics 20010501

• Inhibition of adenylyl cyclase activity in brain membrane fractions by arachidonic acid and related unsaturated fatty acids.

  Archives of biochemistry and biophysics 20010501

• Design, synthesis and biological evaluation of a sulfonylcyanoguanidine as thromboxane A2 receptor antagonist and thromboxane synthase inhibitor.

  The Journal of pharmacy and pharmacology 20010501

• Effects of steroidal and non-steroidal antiphlogistic drugs on eicosanoid synthesis in irritated skin: studies with the isolated perfused bovine udder.

  The Journal of pharmacy and pharmacology 20010501

• Evidence for a role for phospholipase C, but not phospholipase A2, in platelet activation in response to low concentrations of collagen.

  Thrombosis and haemostasis 20010501

• Serotonin 5-HT1 receptors potentiate histamine and thrombin stimulated prostaglandin synthesis in endothelial cells.

  Thrombosis and haemostasis 20010501

• NQ-Y15 inhibits the calcium mobilization by elevation of cyclic AMP in rat platelets.

  Biological & pharmaceutical bulletin 20010501

• Saturated non-esterified fatty acids stimulate de novo diacylglycerol synthesis and protein kinase c activity in cultured aortic smooth muscle cells.

  Diabetologia 20010501

• A novel series of thromboxane A2 synthetase inhibitors with free radical scavenging and anti-peroxidative activities.

  Chemical & pharmaceutical bulletin 20010501

• Propofol potentiates phenylephrine-induced contraction via cyclooxygenase inhibition in pulmonary artery smooth muscle.

  Anesthesiology 20010501

• Beta-lactam antibiotic-mediated changes in platelet reactivity and vascular endothelial functions.

  Pharmacology & toxicology 20010501

• Polyunsaturated fatty acids influence neonatal monocyte survival.

  Pediatric surgery international 20010501

• Mechanisms of cytokine-induced death of cultured bovine luteal cells.

  Reproduction (Cambridge, England) 20010501

• Effect of sesamin on mitochondrial and peroxisomal beta-oxidation of arachidonic and eicosapentaenoic acids in rat liver.

  Lipids 20010501

• FcgammaRIIA exogenously expressed in HeLa cells activates the mitogen-activated protein kinase cascade by a mechanism dependent on the endogenous expression of the protein tyrosine kinase Syk.

  European journal of immunology 20010501

• Free radical lipid peroxidation inhibits enzymatic conversion of beta-carotene into vitamin A.

  Bulletin of experimental biology and medicine 20010501

• The Ca2+-sensing receptor activates cytosolic phospholipase A2 via a Gqalpha -dependent ERK-independent pathway.

  The Journal of biological chemistry 20010427

• Selective augmentation of prostacyclin production by combined prostacyclin synthase and cyclooxygenase-1 gene transfer.

  Circulation 20010424

• Studies of insulin secretory responses and of arachidonic acid incorporation into phospholipids of stably transfected insulinoma cells that overexpress group VIA phospholipase A2 (iPLA2beta ) indicate a signaling rather than a housekeeping role for iPLA2beta.

  The Journal of biological chemistry 20010420

• Prooxidant activity of beta-hematin (synthetic malaria pigment) in arachidonic acid micelles and phospholipid large unilamellar vesicles.

  Biochemical pharmacology 20010415

• Activation and priming of neutrophil nicotinamide adenine dinucleotide phosphate oxidase and phospholipase A(2) are dissociated by inhibitors of the kinases p42(ERK2) and p38(SAPK) and by methyl arachidonyl fluorophosphonate, the dual inhibitor of cytosolic and calcium-independent phospholipase A(2).

  Blood 20010415

• Phorbol ester up-regulates capacities for nuclear translocation and phosphorylation of 5-lipoxygenase in Mono Mac 6 cells and human polymorphonuclear leukocytes.

  Blood 20010415

• Trimethyltin-activated cyclooxygenase stimulates tumor necrosis factor-alpha release from glial cells through reactive oxygen species.

  Toxicology and applied pharmacology 20010415

• Arachidonic acid causes cell death through the mitochondrial permeability transition. Implications for tumor necrosis factor-alpha aopototic signaling.

  The Journal of biological chemistry 20010413

• The mitochondrial permeability transition, release of cytochrome c and cell death. Correlation with the duration of pore openings in situ.

  The Journal of biological chemistry 20010413

• Inhibition studies of soybean and human 15-lipoxygenases with long-chain alkenyl sulfate substrates.

  Biochemistry 20010410

• Enhancement of arachidonic acid release and prostaglandin F(2alpha) formation by Na3VO4 in PC12 cells and GH3 cells.

  European journal of pharmacology 20010406

• Heat pretreatment differentially affects cardiac fatty acid accumulation during ischemia and postischemic reperfusion.

  American journal of physiology. Heart and circulatory physiology 20010401

• Sodium salicylate increases CYP2E1 levels and enhances arachidonic acid toxicity in HepG2 cells and cultured rat hepatocytes.

  Molecular pharmacology 20010401

• Protein kinase C-alpha coordinately regulates cytosolic phospholipase A(2) activity and the expression of cyclooxygenase-2 through different mechanisms in mouse keratinocytes.

  Molecular pharmacology 20010401

• Mesangial cells release untransformed prostaglandin H2 as a major prostanoid.

  Kidney international 20010401

• Docosahexaenoic acid improves long-term potentiation attenuated by phospholipase A(2) inhibitor in rat hippocampal slices.

  British journal of pharmacology 20010401

• Spin trapping agents (Tempol and POBN) protect HepG2 cells overexpressing CYP2E1 against arachidonic acid toxicity.

  Free radical biology & medicine 20010401

• Arachidonic acid protects neonatal rat cardiac myocytes from ischaemic injury through epsilon protein kinase C.

  Cardiovascular research 20010401

• Modulation of rat erg1, erg2, erg3 and HERG K+ currents by thyrotropin-releasing hormone in anterior pituitary cells via the native signal cascade.

  The Journal of physiology 20010401

• Receptor-stimulated phospholipase A(2) liberates arachidonic acid and regulates neuronal excitability through protein kinase C.

  Journal of neurophysiology 20010401

• The disabled dendritic cell.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010401

• Evaluation of the effects of peptide antibiotics human beta-defensins-1/-2 and LL-37 on histamine release and prostaglandin D(2) production from mast cells.

  European journal of immunology 20010401

• gamma-Aminobutyric acid(A) neurotransmission and cerebral ischemia.

  Journal of neurochemistry 20010401

• Signal transduction pathways for activation of extracellular signal-regulated kinase by arachidonic acid in rat neutrophils.

  Journal of leukocyte biology 20010401

• Antiplatelet mechanism of 2-chloro-3-(4-hexylphenyl)-amino-1,4-naphthoquinone (NQ304), an antithrombotic agent.

  Pharmacology & toxicology 20010401

• Eicosatetraynoic acid (ETYA), a non-metabolizable analogue of arachidonic acid, blocks the fast-inactivating potassium current of rat pituitary melanotrophs.

  Canadian journal of physiology and pharmacology 20010401

• Binding of recombinant apolipoprotein(a) to human platelets and effect on platelet aggregation.

  Thrombosis and haemostasis 20010401

• Effect of salicis cortex extract on human platelet aggregation.

  Planta medica 20010401

• Activity of soybean lipoxygenase isoforms against esterified fatty acids indicates functional specificity.

  Archives of biochemistry and biophysics 20010401

• Fatty acid patterns in gastric mucosa of stomach cancer patients.

  Yonsei medical journal 20010401

• Synergistic interaction and the role of C-terminus in the activation of TRAAK K+ channels by pressure, free fatty acids and alkali.

  Pflugers Archiv : European journal of physiology 20010401

• Altered mechanisms underlying hypoxic dilation of skeletal muscle resistance arteries of hypertensive versus normotensive Dahl rats.

  Microcirculation (New York, N.Y. : 1994) 20010401

• Regulation of blood-brain barrier permeability.

  Microcirculation (New York, N.Y. : 1994) 20010401

• Lipid and fatty acid profiles in rats consuming different high-fat ketogenic diets.

  Lipids 20010401

• Regulation by long-chain fatty acids of the expression of cholesteryl ester transfer protein in HepG2 cells.

  Lipids 20010401

• Modulation of prostaglandin H synthase activity by conjugated linoleic acid (CLA) and specific CLA isomers.

  Lipids 20010401

• Triple-bonded unsaturated fatty acids are redox active compounds.

  Lipids 20010401

• Synthesis and antiplatelet activity of some 2,7-di(N-cycloamino)-3-phenyl-1,8-naphthyridine derivatives.

  Farmaco (Societa chimica italiana : 1989) 20010401

• Statins enhance arachidonic acid synthesis in hypercholesterolemic patients.

  Nutrition, metabolism, and cardiovascular diseases : NMCD 20010401

• [Mechanisms of long-term synaptic depression in the hippocampus].

  Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20010401

• Detection and identification of subcutaneous adipose tissue protein related to obesity in New Zealand obese mouse.

  Endocrine journal 20010401

• Distinct arachidonate-releasing functions of mammalian secreted phospholipase A2s in human embryonic kidney 293 and rat mastocytoma RBL-2H3 cells through heparan sulfate shuttling and external plasma membrane mechanisms.

  The Journal of biological chemistry 20010330

• Prostaglandin endoperoxide H synthase-1: the functions of cyclooxygenase active site residues in the binding, positioning, and oxygenation of arachidonic acid.

  The Journal of biological chemistry 20010330

• Mutational and X-ray crystallographic analysis of the interaction of dihomo-gamma -linolenic acid with prostaglandin endoperoxide H synthases.

  The Journal of biological chemistry 20010330

• Haloperidol downregulates phospholipase A(2) signaling in rat basal ganglia circuits.

  Brain research 20010330

• Endothelium-derived hyperpolarizing factor : identification and mechanisms of action in human subcutaneous resistance arteries.

  Circulation 20010327

• Arachidonic acid stimulates glucose uptake in 3T3-L1 adipocytes by increasing GLUT1 and GLUT4 levels at the plasma membrane. Evidence for involvement of lipoxygenase metabolites and peroxisome proliferator-activated receptor gamma.

  The Journal of biological chemistry 20010323

• Cloning and characterization of a novel serine/threonine protein phosphatase type 5 from Trypanosoma brucei.

  Gene 20010321

• [Arachidonic acid and prostaglandins, inflammation and oncology].

  Presse medicale (Paris, France : 1983) 20010317

• Rapid down regulation of pyroglutamyl peptidase II activity by arachidonic acid in primary cultures of adenohypophyseal cells.

  Life sciences 20010316

• Prostaglandin biosynthesis by fat body from true armyworms, Pseudaletia unipuncta.

  Insect biochemistry and molecular biology 20010315

• Cis-polyunsaturated fatty acids stimulate beta1 integrin-mediated adhesion of human breast carcinoma cells to type IV collagen by activating protein kinases C-epsilon and -mu.

  Cancer research 20010315

• Red wine polyphenols, in the absence of alcohol, reduce lipid peroxidative stress in smoking subjects.

  Free radical biology & medicine 20010315

• THIK-1 and THIK-2, a novel subfamily of tandem pore domain K+ channels.

  The Journal of biological chemistry 20010309

• Does CDP-choline modulate phospholipase activities after transient forebrain ischemia?

  Brain research 20010302

• Effects of converting enzyme inhibitors on renal P-450 metabolism of arachidonic acid.

  American journal of physiology. Regulatory, integrative and comparative physiology 20010301

• Dose-dependent modulation of apoptosis and cyclooxygenase-2 expression in human 1547 osteosarcoma cells by NS-398, a selective cyclooxygenase-2 inhibitor.

  International journal of oncology 20010301

• Regulation of cytochrome p450 by inflammatory mediators: why and how?

  Drug metabolism and disposition: the biological fate of chemicals 20010301

• Selective dopamine receptor stimulation differentially affects [3H]arachidonic acid incorporation, a surrogate marker for phospholipase A2-mediated neurotransmitter signal transduction, in a rodent model of Parkinson's disease.

  The Journal of pharmacology and experimental therapeutics 20010301

• In vitro based index of topical anti-inflammatory activity to compare a series of NSAIDs.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20010301

• Beta-adrenergic growth regulation of human cancer cell lines derived from pancreatic ductal carcinomas.

  Carcinogenesis 20010301

• Differential effects of ethanol on the expression of cyclo-oxygenase in cultured cortical astrocytes and neurons.

  Journal of neurochemistry 20010301

• Nicotine protects against arachidonic-acid-induced caspase activation, cytochrome c release and apoptosis of cultured spinal cord neurons.

  Journal of neurochemistry 20010301

• Impaired arachidonic (20:4n-6) and docosahexaenoic (22:6n-3) acid synthesis by phenylalanine metabolites as etiological factors in the neuropathology of phenylketonuria.

  Molecular genetics and metabolism 20010301

• Epoxyeicosatrienoic acid-mediated renal vasodilation to arachidonic acid is enhanced in SHR.

  Hypertension (Dallas, Tex. : 1979) 20010301

• Carbachol restores insulin release in diabetic GK rat islets by mechanisms largely involving hydrolysis of diacylglycerol and direct interaction with the exocytotic machinery.

  Pancreas 20010301

• Partitioning of polyunsaturated fatty acids, which prevent cardiac arrhythmias, into phospholipid cell membranes.

  Journal of lipid research 20010301

• Pathogenetic analysis of three cases with a bleeding disorder characterized by defective platelet aggregation induced by Ca2+ ionophores.

  British journal of haematology 20010301

• Modulation of experimental colon tumorigenesis by types and amounts of dietary fatty acids.

  Cancer research 20010301

• Inhibitors of arachidonic acid metabolism have variable effects on calcium signaling pathways.

  American journal of hypertension 20010301

• Contrasting effect of interleukin-4 on the expression of cytosolic phospholipase A2, 5-lipoxygenase and 5-lipoxygenase-activating protein in peritoneal macrophages from control and ovalbumin-sensitized rats.

  European cytokine network 20010301

• Regulation of prostacyclin synthesis by angiotensin II and TNF-alpha in vascular smooth muscle.

  Prostaglandins & other lipid mediators 20010301

• Bovine papillomavirus oncoprotein E5 affects the arachidonic acid metabolism in cells.

  The international journal of biochemistry & cell biology 20010301

• Inhibitory effects of omega-3 fatty acids on protein kinase C activity in vitro.

  Molecular psychiatry 20010301

• Experimental and theoretical investigation of arachidonic acid uptake in macrophages.

  Biochemistry. Biokhimiia 20010301

• The effect of dietary polyunsaturated fatty acid on insulin sensitivity and lipid metabolism in Otsuka Long-Evans Tokushima Fatty (OLETF) rats.

  Prostaglandins, leukotrienes, and essential fatty acids 20010301

• Incorporation and distribution of saturated and unsaturated fatty acids into nuclear lipids of hepatic cells.

  Lipids 20010301

• Effect of Helicobacter pylori eradication on gastric mucosal phospholipid content and its fatty acid composition.

  Journal of gastroenterology and hepatology 20010301

• [Changes in fatty metabolism in patients with liver cirrhosis].

  Nihon rinsho. Japanese journal of clinical medicine 20010301

• Stimulative effect of cadmium on prostaglandin E2 production in primary mouse osteoblastic cells.

  Calcified tissue international 20010301

• Structural determinants of active site binding affinity and metabolism by cytochrome P450 BM-3.

  Archives of biochemistry and biophysics 20010301

• Cyclo-oxygenase 2 inhibitors: an important new drug classification.

  Pain management nursing : official journal of the American Society of Pain Management Nurses 20010301

• Pyrrolidine inhibitors of human cytosolic phospholipase A2. Part 2: synthesis of potent and crystallized 4-triphenylmethylthio derivative 'pyrrophenone'.

  Bioorganic & medicinal chemistry letters 20010226

• Naegleria fowleri amoebae express a membrane-associated calcium-independent phospholipase A(2).

  Biochimica et biophysica acta 20010226

• Prostaglandin levels in stimulated macrophages are controlled by phospholipase A2-activating protein and by activation of phospholipase C and D.

  The Journal of biological chemistry 20010223

• Signaling pathways underlying muscarinic receptor-induced [Ca2+]i oscillations in HEK293 cells.

  The Journal of biological chemistry 20010223

• Il-10 is a central regulator of cyclooxygenase-2 expression and prostaglandin production.

  Journal of immunology (Baltimore, Md. : 1950) 20010215

• Role of nitric oxide in the metabolism of arachidonic acid in the rat anterior pituitary gland.

  Molecular and cellular endocrinology 20010214

• Synthesis of 4-alkoxy-2-phenylquinoline derivatives as potent antiplatelet agents.

  Bioorganic & medicinal chemistry letters 20010212

• Adenovirus-mediated overexpression of catalase in the cytosolic or mitochondrial compartment protects against cytochrome P450 2E1-dependent toxicity in HepG2 cells.

  The Journal of biological chemistry 20010209

• cDNA cloning and expression of a novel cytochrome p450 (cyp4f12) from human small intestine.

  Biochemical and biophysical research communications 20010202

• Detection of endogenous 12-hydroxyeicosatrienoic acid in human tear film.

  Investigative ophthalmology & visual science 20010201

• 12-lipoxygenase in porcine coronary microcirculation: implications for coronary vasoregulation.

  American journal of physiology. Heart and circulatory physiology 20010201

• Somatostatin receptor-mediated arachidonic acid mobilization: evidence for partial agonism of synthetic peptides.

  British journal of pharmacology 20010201

• Etoricoxib (MK-0663): preclinical profile and comparison with other agents that selectively inhibit cyclooxygenase-2.

  The Journal of pharmacology and experimental therapeutics 20010201

• Pasteurella (Mannheimia) haemolytica leukotoxin-induced cytolysis of bovine leukocytes: role of arachidonic acid and its regulation.

  Microbial pathogenesis 20010201

• Circulating antibodies recognizing malondialdehyde-modified proteins in healthy subjects.

  Free radical biology & medicine 20010201

• Increased 15-HPETE production decreases prostacyclin synthase activity during oxidant stress in aortic endothelial cells.

  Free radical biology & medicine 20010201

• Modulation of rat platelet activation by vessel wall-derived prostaglandin and platelet-derived thromboxane: effects of dietary fish oil on thromboxane-prostaglandin balance.

  Atherosclerosis 20010201

• Purine and pyrimidine nucleotide-sensitive phospholipase A(2) in ampulla from frog semicircular canal.

  American journal of physiology. Regulatory, integrative and comparative physiology 20010201

• Biochemical effects of supplemented long-chain polyunsaturated fatty acids in hyperphenylalaninemia.

  Prostaglandins, leukotrienes, and essential fatty acids 20010201

• Arachidonic acid specifically regulates binding of S100A8/9, a heterodimer complex of the S100 class of calcium binding proteins, to human microvascular endothelial cells.

  Atherosclerosis 20010201

• Inhibition of 5-lipoxygenase activity by the natural anti-inflammatory compound aethiopinone.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20010201

• Activity of the leukocyte NADPH oxidase in whole neutrophils and cell-free neutrophil preparations stimulated with long-chain polyunsaturated fatty acids.

  Inflammation 20010201

• Arachidonic acid-induced Ca2+ sensitization of smooth muscle contraction through activation of Rho-kinase.

  Pflugers Archiv : European journal of physiology 20010201

• Lack of effect of the abnormal fatty acid metabolism in NC/Nga mice on their atopic dermatitis.

  Bioscience, biotechnology, and biochemistry 20010201

• Interferon-alpha inhibits cyclooxygenase-1 and stimulates cyclooxygenase-2 expression in bladder cancer cells in vitro.

  Urological research 20010201

• Effects of fluticasone propionate inhalation on levels of arachidonic acid metabolites in patients with chronic obstructive pulmonary disease.

  Mediators of inflammation 20010201

• Modifications in mitochondrial metabolism and ultrastructure and their relationship to tumour growth inhibition by gamma-linolenic acid.

  Molecular and cellular biochemistry 20010201

• Competitive incorporation of arachidonic acid analogs by cultured rat keratinocytes.

  Journal of nutritional science and vitaminology 20010201

• Current prospects for controlling cancer growth with non-cytotoxic agents--nutrients, phytochemicals, herbal extracts, and available drugs.

  Medical hypotheses 20010201

• Possible role of nitric oxide and arachidonic acid pathways in hypoxia-induced contraction of rabbit coronary artery rings.

  Archives of physiology and biochemistry 20010201

• [Effects of ginkgolide B on arachidonic acid metabolizing enzymes and level of intracellular calcium in rat polymorphonuclear leukocytes].

  Yao xue xue bao = Acta pharmaceutica Sinica 20010201

• Transformation of phospholipid membranes by thiyl radicals via cis-trans isomerization of fatty acid residues.

  Advances in colloid and interface science 20010129

• Role of 'platelet-type' 12-lipoxygenase in skin carcinogenesis.

  Cancer letters 20010126

• Roles for nitric oxide and arachidonic acid in the induction of heterosynaptic cerebellar LTD.

  Neuroreport 20010122

• Aspirin promotes TFF2 gene activation in human gastric cancer cell lines.

  FEBS letters 20010119

• Behavioral suppression induced by cannabinoids is due to activation of the arachidonic acid cascade in rats.

  Brain research 20010119

• Prostaglandin H synthase-2 inhibitors interfere with prostaglandin H synthase-1 inhibition by nonsteroidal anti-inflammatory drugs.

  European journal of pharmacology 20010119

• Spin trapping of polyunsaturated fatty acid-derived peroxyl radicals: reassignment to alkoxyl radical adducts.

  Free radical biology & medicine 20010115

• Defective metabolism of leukotriene B4 in the Sjögren-Larsson syndrome.

  Journal of the neurological sciences 20010115

• The endocannabinoid anandamide is a direct and selective blocker of the background K(+) channel TASK-1.

  The EMBO journal 20010115

• Docosahexaenoic acid induces apoptosis in Jurkat cells by a protein phosphatase-mediated process.

  Biochimica et biophysica acta 20010115

• A decrease in remodeling accounts for the accumulation of arachidonic acid in murine mast cells undergoing apoptosis.

  The Journal of biological chemistry 20010112

• Effects of polyunsaturated fatty acids and clofibrate on chicken stearoyl-coA desaturase 1 gene expression.

  Biochemical and biophysical research communications 20010112

• Interaction of S100A8/S100A9-arachidonic acid complexes with the scavenger receptor CD36 may facilitate fatty acid uptake by endothelial cells.

  Biochemistry 20010109

• Helicobacter pylori-induced prostaglandin E(2) synthesis involves activation of cytosolic phospholipase A(2) in epithelial cells.

  The Journal of biological chemistry 20010105

• The N-terminal 'beta-barrel' domain of 5-lipoxygenase is essential for nuclear membrane translocation.

  The Journal of biological chemistry 20010105

• Ceramide binds to the CaLB domain of cytosolic phospholipase A2 and facilitates its membrane docking and arachidonic acid release.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010101

• Cytosolic phospholipase A2-alpha associates with plasma membrane, endoplasmic reticulum and nuclear membrane in glomerular epithelial cells.

  The Biochemical journal 20010101

• Evidence for the presence of phospholipid hydroperoxide glutathione peroxidase in human platelets: implications for its involvement in the regulatory network of the 12-lipoxygenase pathway of arachidonic acid metabolism.

  The Biochemical journal 20010101

• Effects of polyunsaturated fatty acids and prostaglandins on oocyte maturation in a marine teleost, the European sea bass (Dicentrarchus labrax).

  Biology of reproduction 20010101

• Protective effects of dietary docosahexaenoic acid against kainate-induced retinal degeneration in rats.

  Investigative ophthalmology & visual science 20010101

• Brain regional quantification of F-ring and D-/E-ring isoprostanes and neuroprostanes in Alzheimer's disease.

  The American journal of pathology 20010101

• Carcinogen substrate specificity of human COX-1 and COX-2.

  Carcinogenesis 20010101

• Protective action of arachidonic acid against alloxan-induced cytotoxicity and diabetes mellitus.

  Prostaglandins, leukotrienes, and essential fatty acids 20010101

• Is increased arachidonic acid release a cause or a consequence of replicative senescence?

  Experimental gerontology 20010101

• Effect of long-chain fatty acids in the culture medium on fatty acid composition of WEHI-3 and J774A.1 cells.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20010101

• The ligand that came from within.

  Trends in pharmacological sciences 20010101

• The ligands/activators for peroxisome proliferator-activated receptor alpha (PPARalpha) and PPARgamma increase Cu2+,Zn2+-superoxide dismutase and decrease p22phox message expressions in primary endothelial cells.

  Metabolism: clinical and experimental 20010101

• Synergistic antidiabetic activities of zinc, cyclo (his-pro), and arachidonic acid.

  Metabolism: clinical and experimental 20010101

• Bacterially produced apolipoprotein D binds progesterone and arachidonic acid, but not bilirubin or E-3M2H.

  Journal of molecular recognition : JMR 20010101

• Cytochrome P450 metabolites of arachidonic acid in the control of renal function.

  Current opinion in nephrology and hypertension 20010101

• The composition of saturated fatty acids in plasma phospholipids changes in a way to counteract changes in the mean melting point during pregnancy.

  Lipids 20010101

• How to close a gap junction channel. Efficacies and potencies of uncoupling agents.

  Methods in molecular biology (Clifton, N.J.) 20010101

• Effects of ethanol and arachidonic acid pathway inhibitors on the effectiveness of gastric mucosa cytoprotection.

  Folia morphologica 20010101

• [Update on the treatment with platelet antiaggregation agents].

  Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 20010101

• [Effect of inhibitors of cyclooxygenase and lipoxygenase pathways of arachidonic acid oxidation on the immune response and the activity of the monoxygenase system and lipid peroxidation in the spleen and liver in mice].

  Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20010101

• Endoscopic comparison of the gastroduodenal safety and the effects on arachidonic acid products between meloxicam and piroxicam in the treatment of osteoarthritis.

  Clinical rheumatology 20010101

• Discovery of gemifloxacin (Factive, LB20304a): a quinolone of a new generation.

  Farmaco (Societa chimica italiana : 1989) 20010101

• Persistent pulmonary hypertension of the newborn: experience in a single institution.

  Acta paediatrica Taiwanica = Taiwan er ke yi xue hui za zhi 20010101

• Mechanism of GnRH receptor signaling on gonadotropin release and gene expression in pituitary gonadotrophs.

  Vitamins and hormones 20010101

• Drug-induced urticaria.

  European journal of dermatology : EJD 20010101

• Evaluation of the activity and localization of 15-lipoxygenase-1 after introduction into human colorectal carcinoma Caco-2 cells.

  Prostaglandins, leukotrienes, and essential fatty acids 20010101

• Effect of arachidonic acid-rich oil on lipids and arachidonate metabolites in ethanol- treated rats.

  Prostaglandins, leukotrienes, and essential fatty acids 20010101

• Regulation of preglomerular microvascular 20-hydroxyeicosatetraenoic acid levels by salt depletion.

  Medical science monitor : international medical journal of experimental and clinical research 20010101

• Sites of conditional essential fatty acid deficiency in end stage liver disease.

  JPEN. Journal of parenteral and enteral nutrition 20010101

• [Effect of arachidonic acid on potato tubers during storage].

  Prikladnaia biokhimiia i mikrobiologiia 20010101

• [Adaptive changes in fatty acid compositions of whitefish Coregonus lavaretus L. tissue lipids induced by anthropogenic factors].

  Prikladnaia biokhimiia i mikrobiologiia 20010101

• [Arachidonoylcholine and N,N-dimethylaminoethyl arachidonate are new cholinergic compounds].

  Bioorganicheskaia khimiia 20010101

• Relative contributions of cyclooxygenase- and cytochrome P450 omega-hydroxylase-dependent pathways to hypoxic dilation of skeletal muscle resistance arteries.

  Journal of vascular research 20010101

• Effects of 1alpha,25-(OH)(2)D(3) on rat growth zone chondrocytes are mediated via cyclooxygenase-1 and phospholipase A(2).

  Journal of cellular biochemistry. Supplement 20010101

• Plasma free fatty acid and lipoproteins as sources of polyunsaturated fatty acid for the brain.

  Journal of molecular neuroscience : MN 20010101

• NMR and isotope ratio mass spectrometry studies of in vivo uptake and metabolism of polyunsaturates by the developing rat brain.

  Journal of molecular neuroscience : MN 20010101

• Paroxysmal hemicranias.

  Clinical neuropharmacology 20010101

• The niacin skin flush test in schizophrenia: a replication study.

  International journal of clinical practice 20010101

• Potential role of antioxidants during ethanol-induced changes in the fatty acid composition and arachidonic acid metabolites in male Wistar rats.

  Cell biology and toxicology 20010101

• The comparative release of FGF1 by hypoxia and temperature stress.

  Growth factors (Chur, Switzerland) 20010101

• Effects of sex hormones on Na+/glucose cotransporter of renal proximal tubular cells following oxidant injury.

  Kidney & blood pressure research 20010101

• The role of eicosanoids in the process of adaptation following massive bowel resection in the rat.

  JPEN. Journal of parenteral and enteral nutrition 20010101

• The effect of prostaglandin E2 and arachidonic acid on dentinogenesis in pigs.

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  Endocrinology 19971001

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  Free radical biology & medicine 19960101

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  Stroke 19931001

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  Immunology 19920501

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