50607-30-2 | 2,4-Piperidinedione

Packsize	Purity	Availability	Price	Discounted Price
250mg	98%	in stock	$8.00	$5.00
1g	98%	in stock	$10.00	$7.00
5g	98%	in stock	$20.00	$14.00
25g	98%	in stock	$85.00	$59.00

Description

• Catalog Number: AB78389
• Chemical Name: 2,4-Piperidinedione
• CAS Number: 50607-30-2
• Molecular Formula: C5H7NO2
• Molecular Weight: 113.1146
• MDL Number: MFCD08704814
• SMILES: O=C1CCNC(=O)C1

Computed Properties

• Complexity: 130
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 8
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 1
• XLogP3: -0.8

Upstream Synthesis Route

The upstream synthesis route for 2,4-piperidinedione typically involves the following steps:

1. Start with succinimide as the precursor, which can be obtained through the cyclization of succinic acid with ammonia or through the dehydration of ammonium succinate.

2. Submit succinimide to a hydrogenation process using a catalyst, such as palladium on carbon, under elevated pressure and temperature to reduce the double bond and form pyrrolidone.

3. Perform a ring expansion reaction of pyrrolidone using dehydrating agents, such as phosphorus oxychloride, to yield the target compound, 2,4-piperidinedione.

Each step should be carefully optimized and controlled to ensure high yield and purity of the final product.

Literature

• (R)-(+)-Dimeth-yl[4-oxido-2-oxo-1-(1-phenyl-eth-yl)-1,2,5,6-tetra-hydro-pyridin-3-yl]sulfonium.

  Acta crystallographica. Section E, Structure reports online 20110201

• Preparation and intramolecular [2+2]-photocycloaddition of 1,5-dihydropyrrol-2-ones and 5,6-dihydro-1H-pyridin-2-ones with C-, N-, and O-linked alkenyl side chains at the 4-position.

  The Journal of organic chemistry 20080321

• A quantitative structure-activity relationship study of herbicidal analogues of alpha-hydroxy-substituted 3-benzylidenepyrrolidene-2,4-diones.

  Journal of agricultural and food chemistry 20060920