51-21-8 | 5-fluoro-1,2,3,4-tetrahydropyrimidine-2,4-dione

Packsize	Purity	Availability	Price	Discounted Price
10g	98%	in stock	$8.00	$5.00
50g	98%	in stock	$26.00	$18.00
100g	98%	in stock	$48.00	$33.00
250g	98%	in stock	$110.00	$77.00
500g	98%	in stock	$208.00	$145.00

Description

• Catalog Number: AB69282
• Chemical Name: 5-fluoro-1,2,3,4-tetrahydropyrimidine-2,4-dione
• CAS Number: 51-21-8
• Molecular Formula: C4H3FN2O2
• Molecular Weight: 130.0772
• MDL Number: MFCD00006018
• SMILES: Fc1c[nH]c(=O)[nH]c1=O

Computed Properties

• Complexity: 199
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 9
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 2
• XLogP3: -0.9

Upstream Synthesis Route

5-Fluorouracil, also known as 5-FU, is a potent chemotherapy medication that is commonly used in the treatment of various types of cancer, including colorectal, breast, and skin cancers. Its mechanism of action involves inhibiting the synthesis of DNA and RNA, thereby preventing cancer cells from proliferating and ultimately leading to their death.In chemical synthesis, 5-Fluorouracil serves as a valuable building block for the preparation of various fluorinated compounds. Its unique structure, with a fluorine atom attached to the pyrimidine ring, imparts distinct properties that can be leveraged in the development of novel molecules for pharmaceutical and agrochemical applications. By incorporating 5-Fluorouracil into organic synthesis pathways, chemists can access a diverse array of fluorinated derivatives with enhanced bioactivity and pharmacokinetic profiles.Beyond its traditional role as a cancer treatment agent, 5-Fluorouracil's versatility in chemical synthesis highlights its potential as a key intermediate for the synthesis of fluorinated compounds with therapeutic or industrial significance. Whether utilized in medicinal chemistry research or applied in the development of new materials, 5-Fluorouracil remains a valuable tool in the hands of chemists seeking to create innovative molecules with beneficial properties.