5119-48-2 | Withaferin a

Packsize	Purity	Availability	Price	Discounted Price
1mg	98%	in stock	$36.00	$25.00
5mg	98%	in stock	$72.00	$50.00
10mg	98%	in stock	$118.00	$82.00
25mg	98%	in stock	$242.00	$169.00
100mg	98%	in stock	$733.00	$513.00
250mg	98%	in stock	$1,529.00	$1,070.00

Description

• Catalog Number: AG23080
• Chemical Name: Withaferin a
• CAS Number: 5119-48-2
• Molecular Formula: C28H38O6
• Molecular Weight: 470.5977199999999
• MDL Number: MFCD10687098
• SMILES: OCC1=C(C)C[C@@H](OC1=O)[C@H]([C@H]1CC[C@@H]2[C@]1(C)CC[C@H]1[C@H]2C[C@@H]2[C@]3([C@]1(C)C(=O)C=C[C@@H]3O)O2)C

Upstream Synthesis Route

Withaferin A is a potent bioactive compound isolated from the Withania somnifera plant, also known as Ashwagandha. In chemical synthesis, Withaferin A is widely used as a versatile building block due to its unique chemical structure and diverse reactivity. Its ability to form covalent bonds with various nucleophiles makes it a valuable tool for the construction of complex molecular architectures.One key application of Withaferin A in chemical synthesis is its utility as a Michael acceptor in the synthesis of heterocyclic compounds. By acting as a Michael acceptor, Withaferin A undergoes nucleophilic addition reactions with a range of nucleophiles, such as thiols and amines, leading to the formation of new carbon-carbon and carbon-heteroatom bonds. This reactivity enables the synthesis of structurally diverse compounds with potential biological activities.Additionally, Withaferin A has been employed in the development of novel synthetic methodologies, such as cascade reactions and multicomponent reactions. These strategies harness the unique reactivity of Withaferin A to rapidly assemble complex molecular frameworks in an efficient and cost-effective manner.Overall, the versatile reactivity of Withaferin A in chemical synthesis makes it an invaluable building block for the construction of natural product analogs, drug-like molecules, and other biologically active compounds. Its application continues to inspire innovative approaches in synthetic organic chemistry and drug discovery efforts.