512-15-2 | 2-(dimethylamino)ethyl 2-(1-hydroxycyclopentyl)-2-phenylacetate

Packsize	Purity	Availability	Price	Discounted Price
25mg	98%	in stock	$106.00	$75.00
100mg	98%	in stock	$277.00	$194.00
250mg	98%	in stock	$553.00	$388.00
1g	98%	in stock	$1,506.00	$1,054.00

Description

• Catalog Number: AI51485
• Chemical Name: 2-(dimethylamino)ethyl 2-(1-hydroxycyclopentyl)-2-phenylacetate
• CAS Number: 512-15-2
• Molecular Formula: C17H25NO3
• Molecular Weight: 291.3853
• MDL Number: MFCD00599448
• SMILES: CN(CCOC(=O)[C@H](C1(O)CCCC1)c1ccccc1)C

Computed Properties

• Complexity: 331
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 21
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 7
• Undefined Atom Stereocenter Count: 1
• XLogP3: 2.7

Literature

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• Part-time occlusion therapy for anisometropic amblyopia detected in children eight years of age and older.

  Korean journal of ophthalmology : KJO 20060901

• Secondary bacterial keratitis associated with shield ulcer caused by vernal conjunctivitis.

  Cornea 20060901

• Changes in astigmatism in children with congenital nystagmus.

  Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20060801

• Cataractous changes due to posterior chamber flattening with a posterior chamber phakic intraocular lens secondary to the administration of pilocarpine.

  Ophthalmology 20060801

• Pseudophakic accommodation and pseudoaccommodation under physiological conditions measured with partial coherence interferometry.

  Journal of cataract and refractive surgery 20060801

• Factors associated with childhood strabismus: findings from a population-based study.

  Ophthalmology 20060701

• A comparison of autorefraction and subjective refraction with and without cycloplegia in primary school children.

  American journal of ophthalmology 20060701

• Correctable and non-correctable visual impairment in a population-based sample of 12-year-old Australian children.

  American journal of ophthalmology 20060701

• Analysis of patients with good uncorrected distance and near vision after monofocal intraocular lens implantation.

  Journal of cataract and refractive surgery 20060701

• Accommodative spasm after laser-assisted in situ keratomileusis (LASIK).

  American journal of ophthalmology 20060601

• The effect of phenylephrine and cyclopentolate on objective wavefront measurements.

  Journal of refractive surgery (Thorofare, N.J. : 1995) 20060501

• Macular star associated with Behçet disease.

  Retina (Philadelphia, Pa.) 20060401

• Defining myopia using refractive error and uncorrected logMAR visual acuity >0.3 from 1334 Singapore school children ages 7-9 years.

  The British journal of ophthalmology 20060301

• Safety of intracameral mydriasis in phacoemulsification cataract surgery.

  Journal of cataract and refractive surgery 20060301

• Redilatation with intracameral mydriatics in phacoemulsification surgery.

  Acta ophthalmologica Scandinavica 20060201

• Pharmacological-induced haptic changes and the accommodative performance in patients with the AT-45 accommodative IOL.

  Journal of refractive surgery (Thorofare, N.J. : 1995) 20060201

• Pseudophakic accommodation with 2 models of foldable intraocular lenses.

  Journal of cataract and refractive surgery 20060201

• Higher-order aberrations in children.

  American journal of ophthalmology 20060101

• Pseudallescheria boydii keratitis.

  Journal of pediatric ophthalmology and strabismus 20060101

• Cataract surgery by appointment--a pilot study.

  BMC ophthalmology 20060101

• A preoperative mixture of anesthetic jelly, dilating drops, antibiotics, and anti-inflammatories for cataract surgery.

  Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye 20060101

• Effects of mydriatics on intraocular pressure and pupil size in the normal feline eye.

  Veterinary ophthalmology 20060101

• Toxic keratolysis from combined use of nonsteroid anti-inflammatory drugs and topical steroids following vitreoretinal surgery.

  European journal of ophthalmology 20060101

• Cholinergic innervation of the mouse isolated vas deferens.

  British journal of pharmacology 20051201

• Optical biometry of the anterior eye segment: interexaminer and intraexaminer reliability of ACMaster.

  Journal of cataract and refractive surgery 20051201

• Axial growth and changes in lenticular and corneal power during emmetropization in infants.

  Investigative ophthalmology & visual science 20050901

• Effect of (+) or (-) camphorsulfonic acid additives to the mobile phase on enantioseparations of some basic drugs on a Chiralcel OD column.

  Journal of chromatography. A 20050812

• Accuracy of a new photo-refractometer in young and adult patients.

  Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20050701

• Drug-induced intraocular lens movement and near visual acuity after AcrySof intraocular lens implantation.

  Journal of cataract and refractive surgery 20050701

• Ultrasound biomicroscopy of the rat eye: effects of cholinergic and anticholinergic agents.

  Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20050501

• Comparison of tropicamide and cyclopentolate for cycloplegic refractions in myopic adult refractive surgery patients.

  Journal of cataract and refractive surgery 20050401

• Feasibility of ambulatory overnight oximetry in consecutive patients in a dementia clinic.

  Journal of the American Geriatrics Society 20050301

• Stimulus-driven versus pilocarpine-induced biometric changes in pseudophakic eyes.

  Ophthalmology 20050301

• Quantitative determination of pharmaceuticals using nano-electrospray ionization mass spectrometry after reversed phase mini-solid phase extraction.

  Journal of pharmaceutical and biomedical analysis 20050223

• Potentially accommodating intraocular lenses--an in vitro and in vivo study using three-dimensional high-frequency ultrasound.

  Journal of refractive surgery (Thorofare, N.J. : 1995) 20050101

• Comparison of mydriatic regimens used in screening for retinopathy of prematurity in preterm infants with dark irides.

  Journal of pediatric ophthalmology and strabismus 20050101

• Lack of efficacy of dilated screening for retinoblastoma.

  Journal of pediatric ophthalmology and strabismus 20050101

• Indocyanine green angiography in ocular tuberculosis.

  Ocular immunology and inflammation 20041201

• Comparative study on the safety and efficacy of different cycloplegic agents in children with darkly pigmented irides.

  Clinical & experimental ophthalmology 20041001

• Refractive astigmatism and the toricity of ocular components in human infants.

  Optometry and vision science : official publication of the American Academy of Optometry 20041001

• Parameters of drug antagonism: re-examination of two modes of functional competitive drug antagonism on intraocular muscles.

  The Journal of pharmacy and pharmacology 20040801

• Angioedema related to the use of hyaluronidase in cataract surgery.

  American journal of ophthalmology 20040701

• The effect of off-the-visual-axis retinoscopy on objective refractive measurement.

  American journal of ophthalmology 20040601

• Cycloplegic and mydriatic agents for routine ophthalmologic examination: a survey of pediatric ophthalmologists.

  Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus 20040601

• Grand mal seizure in a child 30 minutes after Cyclogyl (cyclopentolate hydrochloride) and 10% Neo-Synephrine (phenylephrine hydrochloride) eye drops were instilled.

  Pediatrics 20040501

• Evaluation of surgical performance with intracameral mydriatics in phacoemulsification surgery.

  Acta ophthalmologica Scandinavica 20040401

• Comparison of the handheld Retinomax K-Plus2 and on-table autokeratometers in children with and without cycloplegia.

  Journal of cataract and refractive surgery 20040301

• [Phacoemulsification without mydriasis before surgery: benefits to the patient].

  Archivos de la Sociedad Espanola de Oftalmologia 20040201

• Comparison of 6-month results of implantation of the 1CU accommodative intraocular lens with conventional intraocular lenses.

  Ophthalmology 20040201

• Keratitis due to a coelomycetous fungus: case reports and review of the literature.

  Cornea 20040101

• [Syndrome of confusion as side-effect of cycloplegic collyrium].

  Atencion primaria 20040101

• Accuracy of noncycloplegic autorefraction in school-age children in China.

  Optometry and vision science : official publication of the American Academy of Optometry 20040101

• Pupil dilation and wavefront aberration.

  Journal of refractive surgery (Thorofare, N.J. : 1995) 20040101

• The effects of cyclopentolate on intraocular pressure and retrobulbar hemodynamics in patients with pseudoexfoliation syndrome and pseudoexfoliation glaucoma.

  European journal of ophthalmology 20040101

• Clinical evaluation of an eccentric infrared photorefractor: the PowerRefractor.

  Acta ophthalmologica Scandinavica 20031201

• Comparison of measurements of refractive errors between the hand-held Retinomax and on-table autorefractors in cyclopleged and noncyclopleged children.

  American journal of ophthalmology 20031201

• Wavefront analysis in eyes with accommodative spasm.

  American journal of ophthalmology 20031201

• Intracameral mydriatics in phacoemulsification cataract surgery.

  Journal of cataract and refractive surgery 20031201

• Prednisolone and flurbiprofen drops to maintain mydriasis during phacoemulsification cataract surgery.

  Journal of cataract and refractive surgery 20031201

• Use of a wick to deliver preoperative mydriatics for cataract surgery.

  Journal of cataract and refractive surgery 20031101

• Posthypnotic suggestion and the modulation of Stroop interference under cycloplegia.

  Consciousness and cognition 20030901

• Wave-front analysis as screening technique for amblyogenic ametropia with and without cycloplegia.

  Strabismus 20030901

• Neonatal hyphema in precipitous delivery with dinoprostone.

  Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus 20030601

• Acute psychotic reaction caused by topical cyclopentolate use for cycloplegic refraction before refractive surgery: case report and review of the literature.

  Journal of cataract and refractive surgery 20030501

• Intraocular lens movement caused by ciliary muscle contraction.

  Journal of cataract and refractive surgery 20030401

• Herpes zoster virus sclerokeratitis and anterior uveitis in a child following varicella vaccination.

  American journal of ophthalmology 20030301

• Surgically induced miosis during phacoemulsification in patients with diabetes mellitus.

  Eye (London, England) 20030301

• [F99, a mental disorder not otherwise specified].

  Duodecim; laaketieteellinen aikakauskirja 20030101

• Transient paralytic ileus following the use of cyclopentolate-phenylephrine eye drops during screening for retinopathy of prematurity.

  Journal of paediatrics and child health 20030101

• Higher order ocular aberrations after cycloplegic and non-cycloplegic pupil dilation.

  Journal of refractive surgery (Thorofare, N.J. : 1995) 20030101

• The Tehran Eye Study: research design and eye examination protocol.

  BMC ophthalmology 20030101

• Relationship between cycloplegic and wavefront-derived refraction.

  Journal of refractive surgery (Thorofare, N.J. : 1995) 20030101

• Topical mydriatic and cycloplegic spray for Chinese children.

  Journal of pediatric ophthalmology and strabismus 20030101

• Changes in intraocular pressure following diagnostic mydriasis with cyclopentolate 1%.

  Eye (London, England) 20020901

• Efficiency of a video-autorefractometer used as a screening device for amblyogenic factors.

  Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20020901

• [Aberrometry due dilated pupils--Which mydriatic should be used?].

  Klinische Monatsblatter fur Augenheilkunde 20020901

• Pupil location under mesopic, photopic, and pharmacologically dilated conditions.

  Investigative ophthalmology & visual science 20020701

• [Variability in the effects of topical cycloplegics].

  Archivos de la Sociedad Espanola de Oftalmologia 20020601

• Steroid responsive cutaneous Rosai-Dorfman disease associated with uveitis and hypothyroidism.

  Clinical and experimental dermatology 20020601

• [Full optical correction after cycloplegia in headache].

  Journal francais d'ophtalmologie 20020301

• [Cycloplegic effectiveness of cyclopentolate and tropicamide preparations compared with atropinization].

  Vestnik oftalmologii 20020101

• Cycloplegic refractions in healthy children aged 1 through 48 months.

  Archives of ophthalmology (Chicago, Ill. : 1960) 20011101

• Repeat cycloplegic examinations at the Naval Operational Medicine Institute.

  Aviation, space, and environmental medicine 20010901

• Acute gastric dilatation complicating the use of mydriatics in a preterm newborn.

  Pediatric radiology 20010801

• [Biochemical stress monitoring during cataract surgery; phenylephrine 10% shows no changes in serum-catecholamines in comparison with phenylephrine 5%].

  Klinische Monatsblatter fur Augenheilkunde 20010701

• Randomised controlled trial of ketorolac in the management of corneal abrasions.

  Acta ophthalmologica Scandinavica 20010401

• Retinoscopy in infants using a near noncycloplegic technique, cycloplegia with tropicamide 1%, and cycloplegia with cyclopentolate 1%.

  Optometry and vision science : official publication of the American Academy of Optometry 20010401

• Does instilling proxymetacaine before cyclopentolate significantly reduce stinging? The implications of paediatric cycloplegia.

  The British journal of ophthalmology 20010201

• Ocular injury from the venom of the Southern walkingstick.

  Ophthalmology 20010101

• [Experiences with cycloplegic drops in German-speaking centers of pediatric ophthalmology and stabology--results of a 1999 survey].

  Klinische Monatsblatter fur Augenheilkunde 20010101

• Herpes simplex virus bullous keratitis misdiagnosed as a case of pseudophakic bullous keratopathy with secondary glaucoma: an unusual presentation.

  BMC ophthalmology 20010101

• Valsalva retinopathy-like hemorrhage associated with combined trabeculotomy-trabeculectomy in a patient with developmental glaucoma.

  Ophthalmic surgery and lasers 20010101

• Haploinsufficient Bmp4 ocular phenotypes include anterior segment dysgenesis with elevated intraocular pressure.

  BMC genetics 20010101

• Systemic toxicity of topical and periocular corticosteroid therapy in an 11-year-old male with posterior uveitis.

  American journal of ophthalmology 20000801

• Systemic toxicity with cyclopentolate eye drops.

  Indian pediatrics 20000301

• Cyclopentolate and grand mal seizure.

  Bulletin de la Societe belge d'ophtalmologie 19990101

• Seizures associated with 1% cyclopentolate eyedrops.

  Journal of paediatrics and child health 19900401

• [Acute psychosis caused by poisoning with cyclopentolate].

  Klinische Monatsblatter fur Augenheilkunde 19890601

• [Acute psychosis after cyclopentolate-HCL (Zyklolat) (author's transl)].

  Klinische Monatsblatter fur Augenheilkunde 19790701

• Letter: Other systemic effects of eye drops.

  British medical journal 19740309