51481-61-9 | (Z)-3-cyano-1-methyl-2-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl)guanidine

Packsize	Purity	Availability	Price	Discounted Price
1mg	98%	in stock	$8.00	$5.00
1g	98%	in stock	$15.00	$10.00
5g	98%	in stock	$18.00	$12.00
25g	98%	in stock	$42.00	$29.00
100g	98%	in stock	$132.00	$92.00
500g	98%	in stock	$266.00	$186.00

Description

• Catalog Number: AI51548
• Chemical Name: (Z)-3-cyano-1-methyl-2-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl)guanidine
• CAS Number: 51481-61-9
• Molecular Formula: C10H16N6S
• Molecular Weight: 252.3392
• MDL Number: MFCD07774154
• SMILES: N#C/N=C(NCCSCc1nc[nH]c1C)/NC

Computed Properties

• Complexity: 296
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 17
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 7
• XLogP3: 0.4

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• Role of iron in the pathogenesis of cysteamine-induced duodenal ulceration in rats.

  American journal of physiology. Gastrointestinal and liver physiology 20090601

• Organic cation transporters OCT1, 2, and 3 mediate high-affinity transport of the mutagenic vital dye ethidium in the kidney proximal tubule.

  American journal of physiology. Renal physiology 20090601

• Evaluation of the mechanical properties of extrusion-spheronized beads and multiparticulate systems.

  Drug development and industrial pharmacy 20090601

• Pharmacokinetics of cimetidine in dogs after oral administration of cimetidine tablets.

  Journal of veterinary pharmacology and therapeutics 20090601

• Enhanced dissolution rate and synchronized release of drugs in binary systems through formulation: Amorphous naproxen-cimetidine mixtures prepared by mechanical activation.

  Journal of controlled release : official journal of the Controlled Release Society 20090521

• Formulation and characterization of a compacted multiparticulate system for modified release of water-soluble drugs--Part II theophylline and cimetidine.

  Drug development and industrial pharmacy 20090501

• Novel peptidomimetics containing a vinyl ester moiety as highly potent and selective falcipain-2 inhibitors.

  Journal of medicinal chemistry 20090409

• Involvement of human multidrug and toxin extrusion 1 in the drug interaction between cimetidine and metformin in renal epithelial cells.

  The Journal of pharmacology and experimental therapeutics 20090401

• Characterization of histamine-induced relaxation in pre-contracted rat aorta.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20090401

• Enantioselective in-line and off-line CE methods for the kinetic study on cimetidine and its chiral metabolites with reference to flavin-containing monooxygenase genetic isoforms.

  Electrophoresis 20090401

• Antiulcerogenic action of ethanolic extract of the resin from Virola surinamensis Warb. (Myristicaceae).

  Journal of ethnopharmacology 20090318

• The inhibition of human multidrug and toxin extrusion 1 is involved in the drug-drug interaction caused by cimetidine.

  Drug metabolism and disposition: the biological fate of chemicals 20090301

• The copper transporter Ctr1 contributes to cisplatin uptake by renal tubular cells during cisplatin nephrotoxicity.

  American journal of physiology. Renal physiology 20090301

• Rapid correction of metabolic alkalosis in hypertrophic pyloric stenosis with intravenous cimetidine: preliminary results.

  Pediatric surgery international 20090301

• Segmental-dependent membrane permeability along the intestine following oral drug administration: Evaluation of a triple single-pass intestinal perfusion (TSPIP) approach in the rat.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20090215

• Inhibitory effects of the antiepileptic drug ethosuximide on G protein-activated inwardly rectifying K+ channels.

  Neuropharmacology 20090201

• Acetaminophen hepatotoxicity: current management.

  The Mount Sinai journal of medicine, New York 20090201

• Visions of drug discovery. Cimetidine (Tagamet).

  Molecular interventions 20090201

• Non-opioid antinociception produced by brain stem injections of improgan: significance of local, but not cross-regional, cannabinoid mechanisms.

  Brain research 20090109

• Modification of the picryl chloride-induced allergic dermatitis model in mouse ear lobes by 12-O-tetradecanoylphorbol 13-acetate, and analysis of the role of histamine in the modified model.

  International archives of allergy and immunology 20090101

• Effects of cytochrome P450 inducers and inhibitors on the pharmacokinetics of intravenous furosemide in rats: involvement of CYP2C11, 2E1, 3A1 and 3A2 in furosemide metabolism.

  The Journal of pharmacy and pharmacology 20090101

• Influence of the hOCT2 inhibitor cimetidine on the cellular accumulation and cytotoxicity of oxaliplatin.

  International journal of clinical pharmacology and therapeutics 20090101

• Bivariate or composite plots of endpoints.

  Journal of biopharmaceutical statistics 20090101

• Paediatric painful bladder syndrome/interstitial cystitis: diagnosis and treatment.

  Drugs 20090101

• Efficacy comparison between cimetidine and zinc sulphate in the treatment of multiple and recalcitrant warts.

  Anais brasileiros de dermatologia 20090101

• Colorimetric assay of cimetidine in the presence of its oxidative degradates.

  Journal of AOAC International 20090101

• Afferent signalling from the acid-challenged rat stomach is inhibited and gastric acid elimination is enhanced by lafutidine.

  BMC gastroenterology 20090101

• Investigation of biological activity of polar extracts isolated from Phlomis crinita Cav ssp. mauritanica Munby.

  Drug and chemical toxicology 20090101

• Effects of intestinal ischemia/reperfusion on P-glycoprotein mediated biliary and renal excretion of rhodamine123 in rat.

  Drug metabolism and pharmacokinetics 20090101

• Effect of cimetidine on the electrophysiologic profile of isolated visceral sheep peritoneum.

  Advances in peritoneal dialysis. Conference on Peritoneal Dialysis 20090101

• Enhanced ERbeta immunoexpression and apoptosis in the germ cells of cimetidine-treated rats.

  Reproductive biology and endocrinology : RB&E 20090101

• Functional characteristics of two human MATE transporters: kinetics of cimetidine transport and profiles of inhibition by various compounds.

  Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20090101

• Ocular surface tumors.

  Oman journal of ophthalmology 20090101

• Warts (non-genital).

  BMJ clinical evidence 20090101

• Effects of dietary flavonoids on the transport of cimetidine via P-glycoprotein and cationic transporters in Caco-2 and LLC-PK1 cell models.

  Xenobiotica; the fate of foreign compounds in biological systems 20081201

• Possible involvement of radical intermediates in the inhibition of cysteine proteases by allenyl esters and amides.

  Bioorganic & medicinal chemistry letters 20081201

• Emergency pretreatment for contrast allergy before direct percutaneous coronary intervention for ST-elevation myocardial infarction.

  The American journal of cardiology 20081201

• [Effects of H2-blockers on alcohol dehydrogenase (ADH) activity].

  Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20081201

• cis-4-(Piperazin-1-yl)-5,6,7a,8,9,10,11,11a-octahydrobenzofuro[2,3-h]quinazolin-2-amine (A-987306), a new histamine H4R antagonist that blocks pain responses against carrageenan-induced hyperalgesia.

  Journal of medicinal chemistry 20081127

• Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.

  Journal of medicinal chemistry 20081113

• Human CYP3A4-introduced HepG2 cells: in vitro screening system of new chemicals for the evaluation of CYP3A4-inhibiting activity.

  Xenobiotica; the fate of foreign compounds in biological systems 20081101

• Intermittent intravenous pantoprazole and continuous cimetidine infusion: effect on gastric pH control in critically ill patients at risk of developing stressed related mucosal disease.

  The Journal of trauma 20081101

• Choledochoscope manometry about different drugs on the Sphincter of Oddi.

  World journal of gastroenterology 20081014

• Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.

  Journal of medicinal chemistry 20081009

• Cimetidine does not appear to influence the distribution of metformin into human milk.

  British journal of clinical pharmacology 20081001

• Transcellular transport of organic cations in double-transfected MDCK cells expressing human organic cation transporters hOCT1/hMATE1 and hOCT2/hMATE1.

  Biochemical pharmacology 20081001

• Effect of cationic drugs on the transporting activity of human and rat OCT/Oct 1-3 in vitro and implications for drug-drug interactions.

  Xenobiotica; the fate of foreign compounds in biological systems 20080901

• [Metabolism of nicousamide in rat and human liver in vitro].

  Yao xue xue bao = Acta pharmaceutica Sinica 20080901

• Role of organic anion transporters in the pharmacokinetics of zonampanel, an alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate receptor antagonist, in rats.

  Drug metabolism and disposition: the biological fate of chemicals 20080801

• Cimetidine enhances immune response of HBV DNA vaccination via impairment of the regulatory function of regulatory T cells.

  Biochemical and biophysical research communications 20080801

• In response to Tong TC, et al. Comparative treatment of alpha-amanitin poisoning with N-acetylcysteine, benzylpenicillin, cimetidine, thioctic acid, and silybin in a murine model.

  Annals of emergency medicine 20080801

• Predicting glomerular filtration rate in heart transplant recipients using serum creatinine-based equations with cimetidine.

  The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20080801

• Experiences with detection of the ectopic gastric mucosa by means of Tc-99m pertechnetate disodium scintigraphy in children with lower gastrointestinal bleeding.

  European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie 20080801

• Validation of a conscious rat model for the discovery of novel agents that inhibit gastric acid secretion.

  European journal of pharmacology 20080728

• Identification of a potent, selective, and orally active leukotriene a4 hydrolase inhibitor with anti-inflammatory activity.

  Journal of medicinal chemistry 20080724

• Oral aphthous-like lesions, PFAPA syndrome: a review.

  Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20080701

• OCT2 polymorphisms and in-vivo renal functional consequence: studies with metformin and cimetidine.

  Pharmacogenetics and genomics 20080701

• [Interstitial cystitis in 2008].

  Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie 20080701

• [Role of histamine H(1) and H(2) receptors in the modulation of respiratory rhythmical discharge in medulla oblongata slice preparation of neonatal rats].

  Sheng li xue bao : [Acta physiologica Sinica] 20080625

• Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).

  Journal of medicinal chemistry 20080612

• A mechanism for the inhibition of neural progenitor cell proliferation by cocaine.

  PLoS medicine 20080601

• The effect of gastric Acid on the absorption of posaconazole.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20080515

• Coprocessing via spray drying as a formulation platform to improve the compactability of various drugs.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20080501

• Estimating and measuring glomerular filtration rate in children.

  Current opinion in nephrology and hypertension 20080501

• [Stress ulcer prophylaxis in septic patients. Evidence-based overview].

  Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS 20080501

• Intermittent intravenous pantoprazole and continuous cimetidine infusion: effect on gastric pH control in critically ill patients at risk of developing stress-related mucosal disease.

  The Journal of trauma 20080501

• Aquagenic pruritus.

  British journal of hospital medicine (London, England : 2005) 20080501

• Pharmacophore modeling, quantitative structure-activity relationship analysis, and in silico screening reveal potent glycogen synthase kinase-3beta inhibitory activities for cimetidine, hydroxychloroquine, and gemifloxacin.

  Journal of medicinal chemistry 20080410

• Effect of human renal cationic transporter inhibition on the pharmacokinetics of varenicline, a new therapy for smoking cessation: an in vitro-in vivo study.

  Clinical pharmacology and therapeutics 20080401

• Histamine-induced modulation of vascular tone in the isolated chicken basilar artery: a possible involvement of endothelium.

  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20080401

• Acute allergic interstitial nephritis and eosinophiluria.

  Kidney international 20080401

• Ontogenetic noradrenergic lesion alters histaminergic activity in adult rats.

  Neurotoxicity research 20080401

• Specific cerebral heat shock proteins and histamine receptor cross-talking mechanisms promote distinct lead-dependent neurotoxic responses in teleosts.

  Toxicology and applied pharmacology 20080301

• Compound 48/80 induces endothelium-dependent and histamine release-independent relaxation in rabbit aorta.

  Nitric oxide : biology and chemistry 20080301

• High-affinity binding of [3H]cimetidine to a heme-containing protein in rat brain.

  Drug metabolism and disposition: the biological fate of chemicals 20080301

• A study of the pharmacokinetic interactions of the direct renin inhibitor aliskiren with allopurinol, celecoxib and cimetidine in healthy subjects.

  Current medical research and opinion 20080301

• Thiolated chitosan: development and in vitro evaluation of an oral delivery system for acyclovir.

  International journal of pharmaceutics 20080204

• Anti-tumor effects of cimetidine on hepatocellular carcinomas in diethylnitrosamine-treated rats.

  Oncology reports 20080201

• Spectrophotometric determination of H(2)-receptor antagonists via their oxidation with cerium(IV).

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20080101

• Characterization of the transportation of berberine in Coptidis rhizoma extract through rat primary cultured cortical neurons.

  Biomedical chromatography : BMC 20080101

• Paclitaxel and gemcitabine versus carboplatin and gemcitabine in patients with advanced non-small-cell lung cancer. A phase III study of the Hellenic Cooperative Oncology Group.

  Annals of oncology : official journal of the European Society for Medical Oncology 20080101

• Relationship between histamine2-receptor antagonist medications and risk of invasive breast cancer.

  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20080101

• Functional involvement of the organic cation transporter 2 (rOct2) in the renal uptake of organic cations in rats.

  The Journal of international medical research 20080101

• Caki-1 cells as a model system for the interaction of renally secreted drugs with OCT3.

  Nephron. Physiology 20080101

• Characterization of the effect of histamine on mouse corpus cavernosum.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20080101

• Oral premedication for the prevention of hypersensitivity reactions to paclitaxel.

  Medical oncology (Northwood, London, England) 20080101

• Morphological evidences indicate that the interference of cimetidine on the peritubular components is responsible for detachment and apoptosis of Sertoli cells.

  Reproductive biology and endocrinology : RB&E 20080101

• L-type fatty acid binding protein transgenic mouse as a novel tool to explore cytotoxicity to renal proximal tubules.

  Drug metabolism and pharmacokinetics 20080101

• Olfactory interference during inhibitory backward pairing in honey bees.

  PloS one 20080101

• Directional transcellular transport of bisoprolol in P-glycoprotein-expressed LLC-GA5-COL150 cells, but not in renal epithelial LLC-PK1 Cells.

  Drug metabolism and pharmacokinetics 20080101

• Cimetidine inhibits salivary gland tumor cell adhesion to neural cells and induces apoptosis by blocking NCAM expression.

  BMC cancer 20080101

• Antiulcer and gastric antisecretory effects of Landolphia owariensis extracts in rats.

  Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria 20080101

• Impaired expression and function of breast cancer resistance protein (Bcrp) in brain cortex of streptozocin-induced diabetic rats.

  Biochemical pharmacology 20071215

• Simple and universal HPLC-UV method to determine cimetidine, ranitidine, famotidine and nizatidine in urine: application to the analysis of ranitidine and its metabolites in human volunteers.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20071215

• Degranulation of mast cells and histamine release involved in rat pain-related behaviors and edema induced by scorpion Buthus martensi Karch venom.

  European journal of pharmacology 20071201

• A comparative study of histamine activities on differentiation of osteoblasts and osteoclasts.

  The Journal of toxicological sciences 20071201

• Hepatoprotective effect of tocopherol against isoniazid and rifampicin induced hepatotoxicity in albino rabbits.

  Indian journal of experimental biology 20071201

• Effect of sodium ozagrel on the activity of rat CYP2D6.

  European journal of pharmacology 20071114

• Significance of cannabinoid CB1 receptors in improgan antinociception.

  The journal of pain : official journal of the American Pain Society 20071101

• Cimetidine and dapsone-mediated methaemoglobinaemia.

  Anaesthesia 20071101

• Intermittent unexplained abdominal pain: is it porphyria?

  Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20071101

• Antinociceptive activity of furan-containing congeners of improgan and ranitidine.

  Bioorganic & medicinal chemistry letters 20071015

• Improvement of patient tolerance to dapsone: current and future developments.

  Dermatology online journal 20071013

• Effect of N-acetylcysteine on renal function in patients with chronic kidney disease.

  Nephrology (Carlton, Vic.) 20071001

• [Ligustrazine and cimetidine therapy for the prevention of Henoch-Schonlein purpura nephritis in children: a follow-up study of 380 cases].

  Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20071001

• Prophylactic effect of lafutidine against the adverse reaction induced in rat stomach by repeated administration of 5-fluorouracil.

  Inflammopharmacology 20071001

• Possible involvement of organic anion and cation transporters in renal excretion of xanthine derivatives, 3-methylxanthine and enprofylline.

  Life sciences 20070922

• Evaluation of the antiulcerogenic activity of Maytenus robusta (Celastraceae) in different experimental ulcer models.

  Journal of ethnopharmacology 20070905

• Convenient and rapid determination of cimetidine in human plasma using perchloric acid-mediated plasma protein precipitation and high-performance liquid chromatography.

  Biomedical chromatography : BMC 20070901

• Comparative treatment of alpha-amanitin poisoning with N-acetylcysteine, benzylpenicillin, cimetidine, thioctic acid, and silybin in a murine model.

  Annals of emergency medicine 20070901

• Possible involvement of 5-lipoxygenase metabolite in itch-associated response of mosquito allergy in mice.

  Journal of pharmacological sciences 20070901

• Unexpected products and reaction mechanisms of the aqueous chlorination of cimetidine.

  Environmental science & technology 20070901

• Effect of a proton pump inhibitor or an H2-receptor antagonist on prevention of bleeding from ulcer after endoscopic submucosal dissection of early gastric cancer: a prospective randomized controlled trial.

  The American journal of gastroenterology 20070801

• Organic cation transport in the rat kidney in vivo visualized by time-resolved two-photon microscopy.

  Kidney international 20070801

• Conjunctivitis as a sign of PFAPA syndrome.

  Ophthalmology 20070801

• In vivo two-photon fluorescence microscopy opens a new area for investigation of the excretion of cationic drugs in the kidney.

  Kidney international 20070801

• Functional involvement of organic cation transporter1 (OCT1/Oct1) in the hepatic uptake of organic cations in humans and rats.

  Xenobiotica; the fate of foreign compounds in biological systems 20070801

• Substrate specificity of MATE1 and MATE2-K, human multidrug and toxin extrusions/H(+)-organic cation antiporters.

  Biochemical pharmacology 20070715

• Molecular identification and functional characterization of rabbit MATE1 and MATE2-K.

  American journal of physiology. Renal physiology 20070701

• Use of histamine2-antagonists for the treatment of verruca vulgaris.

  The Annals of pharmacotherapy 20070701

• In vitro availability studies of enoxacin in presence of H2 receptor antagonists.

  Pakistan journal of pharmaceutical sciences 20070701

• Disulfiram inhibits defluorination of (18)F-FCWAY, reduces bone radioactivity, and enhances visualization of radioligand binding to serotonin 5-HT1A receptors in human brain.

  Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20070701

• Active renal secretion of NXY-059, a novel neuroprotectant, is mediated via an organic acid transporter.

  Journal of clinical pharmacology 20070701

• [Enzyme kinetics of schizandrin metabolism and sex differences in rat liver microsomes].

  Yao xue xue bao = Acta pharmaceutica Sinica 20070701

• Improgan-induced hypothermia: a role for cannabinoid receptors in improgan-induced changes in nociceptive threshold and body temperature.

  Brain research 20070604

• Possible multiple transporters were involved in hepatobiliary excretion of antofloxacin in rats.

  Xenobiotica; the fate of foreign compounds in biological systems 20070601

• Comparison of the kinetic characteristics of inhibitory effects exerted by biguanides and H2-blockers on human and rat organic cation transporter-mediated transport: Insight into the development of drug candidates.

  Xenobiotica; the fate of foreign compounds in biological systems 20070601

• A new technique for assaying cytochrome P450 enzyme activity in a single cell.

  Cell biology and toxicology 20070501

• Pathogenic importance of pepsin in ischemia/reperfusion-induced gastric injury.

  Life sciences 20070501

• Transport characteristics of zolmitriptan in a human intestinal epithelial cell line Caco-2.

  The Journal of pharmacy and pharmacology 20070501

• Identification of zebrafish histamine H1, H2 and H3 receptors and effects of histaminergic ligands on behavior.

  Biochemical pharmacology 20070415

• Aquatic toxicity of acetaminophen, carbamazepine, cimetidine, diltiazem and six major sulfonamides, and their potential ecological risks in Korea.

  Environment international 20070401

• A comparison between the cardiovascular actions of urocortin 1 and urocortin 2 (stresscopin-related peptide) in conscious rats.

  The Journal of pharmacology and experimental therapeutics 20070401

• CC12, a high-affinity ligand for [3H]cimetidine binding, is an improgan antagonist.

  Neuropharmacology 20070401

• In vitro interactions of captopril with H2-receptor antagonists.

  Pakistan journal of pharmaceutical sciences 20070401

• Baccharis dracunculifolia, the main botanical source of Brazilian green propolis, displays antiulcer activity.

  The Journal of pharmacy and pharmacology 20070401

• Cimetidine induces apoptosis of human salivary gland tumor cells.

  Oncology reports 20070301

• Cimetidine inhibits epidermal growth factor-induced cell signaling.

  Journal of gastroenterology and hepatology 20070301

• Stress-ulcer prophylaxis for general medical patients: a review of the evidence.

  Journal of hospital medicine 20070301

• Investigation of the mechanisms underlying the gastroprotective effect of nicorandil.

  Pharmacology 20070101

• Effects of histamine 2 receptor antagonists on endothelial-neutrophil adhesion and surface expression of endothelial adhesion molecules induced by high glucose levels.

  Journal of diabetes and its complications 20070101

• Clozapine case series.

  Psychosomatics 20070101

• Fosinopril H(2)-receptor antagonists interaction studies by derivative spectroscopy.

  Pakistan journal of pharmaceutical sciences 20070101

• Giant hypertrophic gastritis (Menetrier's-like disease) in an Old English sheepdog.

  Journal of the American Animal Hospital Association 20070101

• Effect of cimetidine on hepatotoxicity induced by isoniazid-rifampicin combination in rabbits.

  Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology 20070101

• A new sensitive flow-injection chemiluminescence method for the determination of H(2)-receptor antagonists.

  Luminescence : the journal of biological and chemical luminescence 20070101

• [Usefulness of equations based on serum cystatin C concentration in the study of renal function].

  Medicina 20070101

• PI3 kinase dependent stimulation of gastric acid secretion by dexamethasone.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20070101

• Creatinine clearance after cimetidine administration: is it useful in the monitoring of the function of transplanted kidney?

  Renal failure 20070101

• Nerolidol, an antiulcer constituent from the essential oil of Baccharis dracunculifolia DC (Asteraceae).

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20070101

• Comparison of the effectiveness of geranylgeranylacetone with cimetidine in gastritis patients with dyspeptic symptoms and gastric lesions: a randomized, double-blind trial in Japan.

  Digestion 20070101

• Cimetidine use and the risk for prostate cancer: results from the VITAL cohort study.

  Annals of epidemiology 20061201

• [Safety of proton pump inhibitors].

  Medicina clinica 20061125

• Cannabinoid-improgan cross-tolerance: Improgan is a cannabinomimetic analgesic lacking affinity at the cannabinoid CB1 receptor.

  European journal of pharmacology 20061107

• Molecular identification and functional characterization of rat multidrug and toxin extrusion type transporter 1 as an organic cation/H+ antiporter in the kidney.

  Drug metabolism and disposition: the biological fate of chemicals 20061101

• The intracellular genistein metabolite 5,7,3',4'-tetrahydroxyisoflavone mediates G2-M cell cycle arrest in cancer cells via modulation of the p38 signaling pathway.

  Free radical biology & medicine 20061015

• Expression and transport activity of breast cancer resistance protein (Bcrp/Abcg2) in dually perfused rat placenta and HRP-1 cell line.

  The Journal of pharmacology and experimental therapeutics 20061001

• Effect of acid secretion blockade on acute gastric mucosal lesions induced by Tityus serrulatus scorpion toxin in anaesthetized rats.

  Toxicon : official journal of the International Society on Toxinology 20061001

• Sedation corner 13.

  SADJ : journal of the South African Dental Association = tydskrif van die Suid-Afrikaanse Tandheelkundige Vereniging 20061001

• Antinociceptive activity of chemical congeners of improgan: optimization of side chain length leads to the discovery of a new, potent, non-opioid analgesic.

  Neuropharmacology 20060901

• [Effect of histamine on intracortical blood vessels of rats].

  Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20060901

• Histamine induces interleukin-6 expression in the human synovial sarcoma cell line (SW982) through the H1 receptor.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20060901

• Cimetidine induces interleukin-18 production through H2-agonist activity in monocytes.

  Molecular pharmacology 20060801

• Identification and functional characterization of a new human kidney-specific H+/organic cation antiporter, kidney-specific multidrug and toxin extrusion 2.

  Journal of the American Society of Nephrology : JASN 20060801

• Fasting duration influences the inhibition of food intake by histamine in chickens.

  Physiology & behavior 20060730

• Neurotoxic pyridinium metabolites of haloperidol are substrates of human organic cation transporters.

  Drug metabolism and disposition: the biological fate of chemicals 20060701

• Effects of sucralfate, cimetidine and rabeprazole on mucosal hydroxyproline content in healing of ethanol-hcl-induced gastric lesions.

  Clinical and experimental pharmacology & physiology 20060701

• The PFAPA syndrome in oral medicine: differential diagnosis and treatment.

  Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20060701

• Emergency department treatment of anaphylaxis: is epinephrine always indicated?

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20060701

• Creatinine for evaluation of glomerular filtration rate in children.

  Clinical pediatrics 20060701

• Oral cimetidine adjuvant therapy for recalcitrant, diffuse conjunctival papillomatosis.

  Cornea 20060701

• Cimetidine does not prevent lung injury in newborn premature infants.

  Pediatric research 20060601

• Histamine modulates mast cell degranulation through an indirect mechanism in a model IgE-mediated reaction.

  European journal of immunology 20060601

• Histamine-induced enhancement of vasopressin and oxytocin secretion in rat neurohypophyseal tissue cultures.

  Regulatory peptides 20060515

• Efficacy and safety of ecabet sodium on functional dyspepsia: a prospective, double-blinded, randomized, multi-center controlled trial.

  World journal of gastroenterology 20060507

• Tetraethylammonium and nicotine transport by the Malpighian tubules of insects.

  Journal of insect physiology 20060501

• Biowaiver monographs for immediate release solid oral dosage forms: cimetidine.

  Journal of pharmaceutical sciences 20060501

• Cimetidine, an unexpected anti-tumor agent, and its potential for the treatment of glioblastoma (review).

  International journal of oncology 20060501

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• Interventions for cutaneous molluscum contagiosum.

  The Cochrane database of systematic reviews 20060419

• Effect of endogenous histamine in the ventral hippocampus on fear memory deficits induced by scopolamine as evaluated by step-through avoidance response in rats.

  Physiology & behavior 20060415

• Mechanisms of the vasorelaxant effect of Danshen (Salvia miltiorrhiza) in rat knee joints.

  Journal of ethnopharmacology 20060406

• Orally administered FPRL1 receptor agonist peptide MMK-1 inhibits etoposide-induced alopecia by a mechanism different from intraperitoneally administered MMK-1.

  Peptides 20060401

• Clinical inquiries. Are oral agents effective for the treatment of verruca vulgaris?

  The Journal of family practice 20060401

• [H2 receptor mediates the protective effect of histamine against the cellular edema and viability reduction induced by oxygen-glucose deprivation in rat hippocampal slices].

  Yao xue xue bao = Acta pharmaceutica Sinica 20060401

• Is the monkey an appropriate animal model to examine drug-drug interactions involving renal clearance? Effect of probenecid on the renal elimination of H2 receptor antagonists.

  The Journal of pharmacology and experimental therapeutics 20060301

• An amino acid transporter involved in gastric acid secretion.

  Pflugers Archiv : European journal of physiology 20060301

• Role of intravenous omeprazole in patients with high-risk peptic ulcer bleeding after successful endoscopic epinephrine injection: a prospective randomized comparative trial.

  The American journal of gastroenterology 20060301

• [Effects of cimetidine on chronotropic response to cardiopulmonary exercise testing].

  Arquivos brasileiros de cardiologia 20060301

• Serum concentration of testosterone, epididymal mast cell population and histamine content in relation to sperm count and their motility in albino rats following H2 receptor blocker treatment.

  Nepal Medical College journal : NMCJ 20060301

• Mechanisms of inverse agonism at histamine H(2) receptors - potential benefits and concerns.

  Inflammopharmacology 20060301

• Prediction of the glomerular filtration rate using equations in kidney-pancreas transplant patients receiving cimetidine.

  Transplantation 20060215

• Differential modulation of cell recruitment and acute edema in a model of Polybia paulista venom-induced inflammation.

  International immunopharmacology 20060201

• Effects of premedication medicines on the formation of the CYP3A4-dependent metabolite of ropivacaine, 2', 6'-Pipecoloxylidide, on human liver microsomes in vitro.

  Basic & clinical pharmacology & toxicology 20060201

• Timed-urine collections for renal clearance studies.

  Pediatric nephrology (Berlin, Germany) 20060101

• Enhanced histamine-mediated contraction of rabbit penile dorsal artery in diet-induced hypercholesterolemia.

  Vascular pharmacology 20060101

• A comparison of oral omeprazole and intravenous cimetidine in reducing complications of duodenal peptic ulcer.

  BMC gastroenterology 20060101

• Putting theory into practice: James Black, receptor theory and the development of the beta-blockers at ICI, 1958-1978.

  Medical history 20060101

• Influence of cimetidine on the anticonvulsant activity of conventional antiepileptic drugs against pentetrazole-induced seizures in mice.

  Pharmacological reports : PR 20060101

• Feasibility of biowaiver extension to biopharmaceutics classification system class III drug products: cimetidine.

  Clinical pharmacokinetics 20060101

• In vitro availability of metformin in presence of h(2) receptor antagonists.

  Pakistan journal of pharmaceutical sciences 20060101

• Bismuth increases hydroxyl radical-scavenging activity of histamine H2-receptor antagonists.

  Pharmacological reports : PR 20060101

• Histamine ameliorates spatial memory deficits induced by MK-801 infusion into ventral hippocampus as evaluated by radial maze task in rats.

  Acta pharmacologica Sinica 20051201

• Cimetidine-induced tubulointerstitial nephritis with both MPO-ANCA and PR3-ANCA.

  Clinical and experimental nephrology 20051201

• Warts.

  Clinical evidence 20051201

• Multiinjection approach for D2 receptor binding quantification in living rats using [11C]raclopride and the beta-microprobe: crossvalidation with in vitro binding data.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20051101

• Alteration of intracellular histamine H2 receptor cycling precedes antagonist-induced upregulation.

  American journal of physiology. Gastrointestinal and liver physiology 20051101

• Effect of histamine and cimetidine on retinal and choroidal blood flow in humans.

  American journal of physiology. Regulatory, integrative and comparative physiology 20051101

• Interaction of organic cations with a newly identified plasma membrane monoamine transporter.

  Molecular pharmacology 20051101

• Enhanced antinociception by intracerebroventricularly administered orexin A in histamine H1 or H2 receptor gene knockout mice.

  Pain 20051101

• Cimetidine and acute intermittent porphyria.

  Annals of internal medicine 20051101

• Transepithelial urate transport by avian renal proximal tubule epithelium in primary culture.

  The Journal of experimental biology 20051101

• Pharmacokinetic interactions of the oral renin inhibitor aliskiren with lovastatin, atenolol, celecoxib and cimetidine.

  International journal of clinical pharmacology and therapeutics 20051101

• Antinociceptive, brain-penetrating derivatives related to improgan, a non-opioid analgesic.

  European journal of pharmacology 20051017

• L-type amino acids stimulate gastric acid secretion by activation of the calcium-sensing receptor in parietal cells.

  American journal of physiology. Gastrointestinal and liver physiology 20051001

• A species difference in the transport activities of H2 receptor antagonists by rat and human renal organic anion and cation transporters.

  The Journal of pharmacology and experimental therapeutics 20051001

• Human organic anion transporter hOAT3 is a potent transporter of cephalosporin antibiotics, in comparison with hOAT1.

  Biochemical pharmacology 20051001

• Effects of a new isoquinolinone derivative on induction of action potential bursts in central snail neuron.

  Pharmacology 20051001

• Effects of dietary or injected organic cations on larval Drosophila melanogaster: mortality and elimination of tetraethylammonium from the hemolymph.

  Archives of insect biochemistry and physiology 20051001

• Multiple dose pharmacokinetics and acute safety of piroxicam and cimetidine in the cat.

  Journal of veterinary pharmacology and therapeutics 20051001

• Continuous infusion interleukin-2 and antihistamines in metastatic kidney cancer.

  Cancer biotherapy & radiopharmaceuticals 20051001

• Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity.

  Current drug metabolism 20051001

• Effect of Cimetidine and Phenobarbital on metabolite kinetics of Omeprazole in rats.

  Archives of pharmacal research 20051001

• [The effect of cimetidine mainly increases CD4+ cells of peripheral blood T lymphocytes].

  Gan to kagaku ryoho. Cancer & chemotherapy 20051001

• Estimation of pK(a) values using microchip capillary electrophoresis and indirect fluorescence detection.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050925

• The effect of cimetidine or omeprazole on the pharmacokinetics of escitalopram in healthy subjects.

  British journal of clinical pharmacology 20050901

• [Study of total alkaloids from Rhizoma Coptis Chinensis on experimental gastric ulcers].

  Chinese journal of integrative medicine 20050901

• Oral sustained delivery of theophylline and cimetidine from in situ gelling pectin formulations in rabbits.

  Drug development and industrial pharmacy 20050901

• Comparison of prostaglandin and cimetidine in protection of isolated gastric glands against indomethacin injury.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20050901

• The cryofixation of isolated rat gastric mucosa provides new insights into the functional transformation of gastric parietal cells: an in vitro experimental model study.

  Archives of histology and cytology 20050901

• Comparison of information on the pharmacokinetic interactions of Ca antagonists in the package inserts from three countries (Japan, USA and UK).

  European journal of clinical pharmacology 20050801

• Inappropriate drug prescribing in older adults: the updated 2002 Beers criteria--a population-based cohort study.

  British journal of clinical pharmacology 20050801

• Adverse haematological effects of vinblastine, prednisolone and cimetidine treatment: a retrospective study in fourteen dogs with mast cell tumours.

  Journal of veterinary medicine. A, Physiology, pathology, clinical medicine 20050801

• Randomized, double-blind study comparing postoperative effects of treatment timing with histamine H-receptor antagonist cimetidine.

  Acta anaesthesiologica Scandinavica 20050701

• Comparative study of the speed of acid-suppressing effects of oral administration of cimetidine and famotidine.

  Journal of gastroenterology and hepatology 20050701

• Effect of topical cimetidine rinse on gingival crevicular neutrophil leukocyte function.

  Journal of periodontology 20050601

• Transcellular transport of creatinine in renal tubular epithelial cell line LLC-PK1.

  Drug metabolism and pharmacokinetics 20050601

• Gastric mucosal injury due to hemorrhagic reperfusion and efficacy of Salvia miltiorrhizae extract F and cimetidine.

  World journal of gastroenterology 20050514

• Ischemia of rat stomach mobilizes ECL cell histamine.

  American journal of physiology. Gastrointestinal and liver physiology 20050501

• Sex-dependent expression and activity of the ATP-binding cassette transporter breast cancer resistance protein (BCRP/ABCG2) in liver.

  Molecular pharmacology 20050501

• The effect of pharmacologically altered gastric pH on cadmium absorption from the diet and its accumulation in murine tissues.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20050501

• A pilot study of weekly paclitaxel administration for patients with relapsed cervical cancer after heavy medication.

  Gan to kagaku ryoho. Cancer & chemotherapy 20050501

• Liquid-phase microextraction based on carrier mediated transport combined with liquid chromatography-mass spectrometry. New concept for the determination of polar drugs in a single drop of human plasma.

  Journal of chromatography. A 20050422

• Positive correlation between sialyl Lewis X expression and pathologic findings in renal cell carcinoma.

  Kidney international 20050401

• UDP-glucuronosyltransferases and clinical drug-drug interactions.

  Pharmacology & therapeutics 20050401

• A study of the in vitro interaction between lidocaine and premedications using human liver microsomes.

  Journal of clinical pharmacy and therapeutics 20050401

• Randomized, double-blind comparison of immediate-release omeprazole oral suspension versus intravenous cimetidine for the prevention of upper gastrointestinal bleeding in critically ill patients.

  Critical care medicine 20050401

• Cimetidine and other histamine2-receptor antagonist use in relation to risk of breast cancer.

  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20050401

• Combined cimetidine and temozolomide, compared with temozolomide alone: significant increases in survival in nude mice bearing U373 human glioblastoma multiforme orthotopic xenografts.

  Journal of neurosurgery 20050401

• In vitro release of tetracyclines in presence of H2-receptor antagonists.

  Pakistan journal of pharmaceutical sciences 20050401

• Impact of gastric acid suppressants on cytochrome P450 3A4 and P-glycoprotein: consequences for FK506 assimilation.

  Kidney international 20050301

• Absence of 5-HT3 and cholinergic mechanisms in improgan antinociception.

  Pharmacology, biochemistry, and behavior 20050301

• Attenuating effect of H+K+ATPase inhibitors on airway cough hypersensitivity induced by allergic airway inflammation in guinea-pigs.

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20050301

• How and when to treat molluscum contagiosum and warts in children.

  Pediatric annals 20050301

• The influence of angiotensin-converting enzyme gene of donor and recipient on the function of transplanted kidney.

  Transplantation proceedings 20050301

• Inhibition of tryptase release from human colon mast cells by histamine receptor antagonists.

  Asian Pacific journal of allergy and immunology 20050301

• Metabolism of territrem B and C in liver microsomes from 14-wk-old Wistar rats is catalyzed by cytochrome P-450 3A.

  Journal of toxicology and environmental health. Part A 20050227

• Central H1 and H2 receptor participation in the control of water and salt intake in rats.

  Physiology & behavior 20050215

• Exploring the role of different drug transport routes in permeability screening.

  Journal of medicinal chemistry 20050127

• Interstitial cystitis in the UK: results of a questionnaire survey of members of the Interstitial Cystitis Support Group.

  European journal of obstetrics, gynecology, and reproductive biology 20050110

• Human breast cancer resistance protein: interactions with steroid drugs, hormones, the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine, and transport of cimetidine.

  The Journal of pharmacology and experimental therapeutics 20050101

• Different effects of three transporting inhibitors, verapamil, cimetidine, and probenecid, on fexofenadine pharmacokinetics.

  Clinical pharmacology and therapeutics 20050101

• [Bronchial asthma and gastroesophageal reflux disease: are they interrelated by chance?].

  Klinicheskaia meditsina 20050101

• Cimetidine as a first-line therapy for pedal verruca: eight-year retrospective analysis.

  Journal of the American Podiatric Medical Association 20050101

• Effect of histamine receptor antagonists on aminophylline-induced seizures and lethality in mice.

  Pharmacological reports : PR 20050101

• Effect of selected alcohol dehydrogenase inhibitors on human hepatic lactate dehydrogenase activity - an in vitro study.

  Journal of applied toxicology : JAT 20050101

• Histamine regulates growth of malignant melanoma implants via H2 receptors in mice.

  Inflammopharmacology 20050101

• Comparison of verapamil and cimetidine for their effects on volume and acidity of Carbachol induced gastric secretion in fasting rabbits.

  Journal of Ayub Medical College, Abbottabad : JAMC 20050101

• [The influence of gene polymorphism of the angiotensin-converting enzyme in donor and recipient on the function of renal graft].

  Annales Academiae Medicae Stetinensis 20050101

• Histamine in idiopathic inflammatory bowel diseases--not a standby player.

  Folia medica Cracoviensia 20050101

• Role of somatostatin receptors on gastric acid secretion in wild-type and somatostatin receptor type 2 knockout mice.

  Naunyn-Schmiedeberg's archives of pharmacology 20041201

• Relative contribution of OAT and OCT transporters to organic electrolyte transport in rabbit proximal tubule.

  American journal of physiology. Renal physiology 20041101

• Impact of cytochrome P-450 inhibition by cimetidine and induction by carbamazepine on the kinetics of hypericin and pseudohypericin in healthy volunteers.

  European journal of clinical pharmacology 20041101

• Degranulation of uterine mast cell modifies contractility of isolated myometrium from pregnant women.

  American journal of obstetrics and gynecology 20041101

• [Treatment of acute pancreatitis with protease inhibitor, H2 receptor antagonist and somatostatin analogue].

  Nihon rinsho. Japanese journal of clinical medicine 20041101

• Treatment of gastric hemorrhage by pulverized omeprazole and antacid--concomitant administration via a nasogastric tube.

  International journal of clinical pharmacology and therapeutics 20041101

• Different transport properties between famotidine and cimetidine by human renal organic ion transporters (SLC22A).

  European journal of pharmacology 20041025

• Effects of cimetidine-like drugs on recombinant GABAA receptors.

  Life sciences 20041008

• Should we be using cimetidine to premedicate patients receiving docetaxel or paclitaxel?

  Gynecologic oncology 20041001

• Cytotoxicity of the phytosterol diosgenin and its derivatives in rat cultured hepatocytes and V79 fibroblasts.

  Human & experimental toxicology 20041001

• The effect of H2 antagonists on proliferation and apoptosis in human colorectal cancer cell lines.

  Digestive diseases and sciences 20041001

• Activation of brain stem nuclei by improgan, a non-opioid analgesic.

  Brain research 20040924

• Evaluation of antinociceptive, anti-inflammatory and antiulcerogenic activities of Maytenus ilicifolia.

  Journal of ethnopharmacology 20040901

• Carrier-mediated uptake of H2-receptor antagonists by the rat choroid plexus: involvement of rat organic anion transporter 3.

  Drug metabolism and disposition: the biological fate of chemicals 20040901

• Role of N-methyl-D-aspartate receptors in gastric mucosal blood flow induced by histamine.

  Journal of neuroscience research 20040901

• Histaminergic H1 and H2 receptors located within the ventromedial hypothalamus regulate food and water intake in rats.

  Pharmacology, biochemistry, and behavior 20040901

• Renal interaction between itraconazole and cimetidine.

  Journal of clinical pharmacology 20040801

• Premedication with H1 and H2 blocking agents reduces the incidence of postoperative nausea and vomiting.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20040801

• Comparison of two formulae for estimation of glomerular filtration rate in children.

  Pediatric nephrology (Berlin, Germany) 20040701

• Human skeletal muscle lactate dehydrogenase activity in the presence of some alcohol dehydrogenase inhibitors.

  Basic & clinical pharmacology & toxicology 20040701

• Extrusion granulation and high shear granulation of different grades of lactose and highly dosed drugs: a comparative study.

  Drug development and industrial pharmacy 20040701

• [A family of acute intermittent porphyria].

  [Rinsho ketsueki] The Japanese journal of clinical hematology 20040701

• Oral pemphigus vulgaris: a case report and literature update.

  Annals of the Academy of Medicine, Singapore 20040701

• Regulation of cytokine production in carcinoembryonic antigen stimulated Kupffer cells by beta-2 adrenergic receptors: implications for hepatic metastasis.

  Cancer letters 20040625

• Mouse reduced in osteosclerosis transporter functions as an organic anion transporter 3 and is localized at abluminal membrane of blood-brain barrier.

  The Journal of pharmacology and experimental therapeutics 20040601

• A lyophilized aqueous extract of Maytenus ilicifolia leaves inhibits histamine-mediated acid secretion in isolated frog gastric mucosa.

  Planta 20040601

• Creatinine transport by basolateral organic cation transporter hOCT2 in the human kidney.

  Pharmaceutical research 20040601

• Renal secretion of the antiviral nucleoside analog AM188 is inhibited by probenecid, p-aminohippuric acid, and cimetidine in the isolated perfused rat kidney.

  Pharmaceutical research 20040601

• Cardiovascular effects of the toxin(s) of the Australian paralysis tick, Ixodes holocyclus, in the rat.

  Toxicon : official journal of the International Society on Toxinology 20040601

• Warts.

  Clinical evidence 20040601

• The ratio of urinary cystatin C to urinary creatinine for detecting decreased GFR.

  Pediatric nephrology (Berlin, Germany) 20040501

• Renal transport of organic compounds mediated by mouse organic anion transporter 3 (mOat3): further substrate specificity of mOat3.

  Drug metabolism and disposition: the biological fate of chemicals 20040501

• Histamine dilutions modulate basophil activation.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20040501

• Organic cation transport by Malpighian tubules of Drosophila melanogaster: application of two novel electrophysiological methods.

  The Journal of experimental biology 20040501

• Methods of GFR determination--creatinine clearance after cimetidine administration in clinical practice.

  Acta medica Austriaca 20040501

• [Complementary medicine. Phytotherapy in gastrointestinal ulcer].

  Praxis 20040414

• Uptake and efflux of quinacrine, a candidate for the treatment of prion diseases, at the blood-brain barrier.

  Cellular and molecular neurobiology 20040401

• The effect of cimetidine on dextromethorphan O-demethylase activity of human liver microsomes and recombinant CYP2D6.

  Drug metabolism and disposition: the biological fate of chemicals 20040401

• Gastric antiulcer activity of Syngonanthus arthrotrichus SILVEIRA.

  Biological & pharmaceutical bulletin 20040301

• Tumour growth inhibition of human pancreatic cancer xenografts in SCID mice by cimetidine.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20040301

• Pain-relieving drugs and the brain histaminergic system: multiple analgesic mechanisms from histamine, improgan and cimetidine.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20040301

• Robin Ganellin gives his views on medicinal chemistry and drug discovery. Interview by Stephen L. Carney.

  Drug discovery today 20040215

• Eosinophilic infiltration of the esophagus: gastroesophageal reflux versus eosinophilic esophagitis in children--discussion on daily practice.

  Journal of pediatric surgery 20040201

• Interactions of human- and rat-organic anion transporters with pravastatin and cimetidine.

  Journal of pharmacological sciences 20040201

• The effect of repeat dosing with cimetidine on the pharmacokinetics of intravenous granisetron in healthy volunteers.

  The Journal of pharmacy and pharmacology 20040201

• The influence of cimetidine on the pharmacokinetics of diltiazem and its main metabolite in rabbits.

  Archives of pharmacal research 20040201

• [Effect of prednisolone on the inhibition of basal gastric secretion in laboratory rats induced by fats or blockade of H2-receptors].

  Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20040201

• Heat shock protein 72 binds and protects dihydrofolate reductase against oxidative injury.

  Biochemical and biophysical research communications 20040102

• High-pressure freezing of isolated gastric glands provides new insight into the fine structure and subcellular localization of H+/K+-ATPase in gastric parietal cells.

  The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 20040101

• Cooperative inhibitory effects of antisense oligonucleotide of cell adhesion molecules and cimetidine on cancer cell adhesion.

  World journal of gastroenterology 20040101

• Effects of Azadirachta indica extract on gastric ulceration and acid secretion in rats.

  Journal of ethnopharmacology 20040101

• Omeprazole is more effective than a histamine H2-receptor blocker for maintaining a persistent elevation of gastric pH after colon resection for cancer.

  American journal of surgery 20040101

• Histamine participates in the early phase of trabecular bone loss in ovariectomized rats.

  Bone 20040101

• Drug-drug interactions evaluated by a highly active reconstituted native human cytochrome P4503A4 and human NADPH-cytochrome P450 reductase system.

  Arzneimittel-Forschung 20040101

• Anti-inflammatory and ulcerogenic effects of indomethacin and tenoxicam in combination with cimetidine.

  Inflammopharmacology 20040101

• Effects of histamine receptor blockade on cardiovascular changes induced by 35 GHz radio frequency radiation heating.

  Autonomic & autacoid pharmacology 20040101

• The effect of H2-receptor antagonist and proton pump inhibitor on microbial proliferation in the stomach.

  Hepato-gastroenterology 20040101

• [Human erythrocyte lactate dehydrogenase activity changes in the presence of some alcohol dehydrogenase inhibitors].

  Roczniki Panstwowego Zakladu Higieny 20040101

• Effect of selected alcohol dehydrogenase inhibitors on the human heart lactate dehydrogenase activity--an in vitro study.

  Acta physiologica Hungarica 20040101

• [The effect of H2 receptor blockers on renal function. An attempt to accurately measure glomerular filtration].

  Annales Academiae Medicae Stetinensis 20040101

• In vitro metabolism of zolmitriptan in rat cytochromes induced with beta-naphthoflavone and the interaction between six drugs and zolmitriptan.

  Chemico-biological interactions 20031215

• Functional mapping of rbOCT1 and rbOCT2 activity in the S2 segment of rabbit proximal tubule.

  American journal of physiology. Renal physiology 20031201

• Critical role of histamine H4 receptor in leukotriene B4 production and mast cell-dependent neutrophil recruitment induced by zymosan in vivo.

  The Journal of pharmacology and experimental therapeutics 20031201

• Histamine H2-receptor antagonists have no clinically significant effect on the steady-state pharmacokinetics of voriconazole.

  British journal of clinical pharmacology 20031201

• The existence of an NAD-dependent pathway for retinoic acid formation from vitamin A (retinol) in rat esophagus and its inhibition by ethanol and histamine 2 (H2) receptor antagonists.

  Medical science monitor : international medical journal of experimental and clinical research 20031201

• Increased tissue survival in experimental skin flaps in mast cell-deficient rats.

  Acta physiologica Scandinavica 20031201

• Involvement of H2-receptors in the mechanism of analgesic action of Tyr-MIF-1.

  Archives of physiology and biochemistry 20031201

• Chemical and analytical characterization of related organic impurities in drugs.

  Analytical and bioanalytical chemistry 20031101

• [Roles of histamine receptors in pain perception: a study using receptors gene knockout mice].

  Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20031101

• Roxatidine- and cimetidine-induced angiogenesis inhibition suppresses growth of colon cancer implants in syngeneic mice.

  Journal of pharmacological sciences 20031101

• Bioequivalence and other unresolved issues in generic drug substitution.

  Clinical therapeutics 20031101

• A flow-injection ultrafiltration sampling chemiluminescence system for on-line determination of drug-protein interaction.

  Analytical and bioanalytical chemistry 20031001

• Histamine and prostaglandin interaction in regulation of oxytocin and vasopressin secretion.

  Journal of neuroendocrinology 20031001

• Mitigation of pennyroyal oil hepatotoxicity in the mouse.

  Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 20031001

• [Cimetidine inhibits the adhesion of cancer cells with sialyl Lewis epitope onto the vascular endothelium].

  Gan to kagaku ryoho. Cancer & chemotherapy 20031001

• [Effect of cimetidine with chemotherapy on stage IV colorectal cancer].

  Gan to kagaku ryoho. Cancer & chemotherapy 20031001

• Treatment of human solid malignancies with autologous activated lymphocytes and cimetidine: a phase II trial of the cancer biotherapy research group.

  Cancer biotherapy & radiopharmaceuticals 20031001

• Development of an HPLC method for the determination of ranitidine and cimetidine in human plasma following SPE.

  Journal of pharmaceutical and biomedical analysis 20030919

• Enhancing and inhibitory effects of H2-receptor antagonists on the GABA and the GABAA-agonist muscimol responses of the isolated guinea pig ileum: a pharmacodynamic interaction.

  Pharmacological research 20030901

• Combination therapy of ecabet sodium and cimetidine compared with cimetidine alone for gastric ulcer: prospective randomized multicenter study.

  Journal of gastroenterology and hepatology 20030901

• Abolition of arteriolar dilation but not constriction to histamine in cremaster muscle of eNOS-/- mice.

  American journal of physiology. Heart and circulatory physiology 20030801

• Histamine inhibits atrial myocytic ANP release via H2 receptor-cAMP-protein kinase signaling.

  American journal of physiology. Regulatory, integrative and comparative physiology 20030801

• Tiotidine, a histamine H2 receptor inverse agonist that binds with high affinity to an inactive G-protein-coupled form of the receptor. Experimental support for the cubic ternary complex model.

  Molecular pharmacology 20030801

• The effects of pyrilamine and cimetidine on mRNA C-fos expression and nociceptive flinching behavior in rats.

  Anesthesia and analgesia 20030801

• Case study: metformin-associated lactic acidosis: could orlistat be relevant?

  Diabetes care 20030801

• Evaluation of the efficacy of antihistamines using human monocyte-derived dendritic cells stimulated with histamine.

  Journal of the American Academy of Dermatology 20030801

• Sodium pentobarbital anesthesia transiently enhances the severity of infection following intragastric, but not intravenous, inoculation of Listeria monocytogenes in mice.

  Microbial pathogenesis 20030801

• [A case of multiple lung metastases of colon cancer with long-term survival following 5'-DFUR and cimetidine therapy].

  Gan to kagaku ryoho. Cancer & chemotherapy 20030801

• Photochemical fate of pharmaceuticals in the environment: cimetidine and ranitidine.

  Environmental science & technology 20030801

• History in our lifetime: the changing nature of refractory duodenal ulcer in the era of histamine H2 receptor antagonists.

  Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20030801

• [Tolerance induction in anaphylaxis to carboplatin].

  Deutsche medizinische Wochenschrift (1946) 20030725

• Contribution of organic anion transporter 3 (Slc22a8) to the elimination of p-aminohippuric acid and benzylpenicillin across the blood-brain barrier.

  The Journal of pharmacology and experimental therapeutics 20030701

• A mechanism of antigen-induced goblet cell degranulation in the nasal epithelium of sensitized rats.

  The Journal of allergy and clinical immunology 20030701

• Spermicidal efficacy of H2-receptor antagonists and potentiation with 2', 4'-dichlorobenzamil hydrochloride: role of intrasperm Ca2+.

  Contraception 20030701

• Comparison of the effects of rebamipide with those of cimetidine on chronic gastritis associated with Helicobacter pylori in Mongolian gerbils.

  Alimentary pharmacology & therapeutics 20030701

• Influence of histamine, cimetidine and pyrilamine on naloxone-induced jumping in morphine-dependent mice.

  European journal of pharmacology 20030620

• Improgan antinociception does not require neuronal histamine or histamine receptors.

  Brain research 20030606

• Effects of anti-allergic drugs on intestinal mastocytosis and worm expulsion of rats infected with Neodiplostomum seoulense.

  The Korean journal of parasitology 20030601

• Proteinase-activated receptor-2 activation induces uterine contractility in term pregnant rats that is not dependent on mast cell activation and cyclo-oxygenase products.

  American journal of obstetrics and gynecology 20030601

• Radioprotective properties of histamine H2 receptor antagonists: present and future prospects.

  Journal of radiation research 20030601

• Synthesis and pharmacological activity of fluorescent histamine H2 receptor antagonists related to potentidine.

  Bioorganic & medicinal chemistry letters 20030519

• Hypersensitivity and idiosyncratic reactions to oxaliplatin.

  Cancer 20030501

• Glucocorticoid involvement in suppression of NK activity following surgery in rats.

  Journal of neuroimmunology 20030501

• Gastric ulceration in an equine neonate.

  The Canadian veterinary journal = La revue veterinaire canadienne 20030501

• The histamine H2-receptor antagonist, cimetidine, inhibits the articular osteopenia in rats with adjuvant-induced arthritis by suppressing the osteoclast differentiation induced by histamine.

  Journal of pharmacological sciences 20030501

• Warifteine and milonine, alkaloids isolated from Cissampelos sympodialis Eichl: cytotoxicity on rat hepatocyte culture and in V79 cells.

  Toxicology letters 20030430

• Comparison of in vitro P-glycoprotein screening assays: recommendations for their use in drug discovery.

  Journal of medicinal chemistry 20030424

• Influence of cimetidine co-administration on the pharmacokinetics of acebutolol enantiomers and its metabolite diacetolol in a rat model: the effect of gastric pH on double-peak phenomena.

  International journal of pharmaceutics 20030414

• Effect of interleukin 6 on the hepatic metabolism of itraconazole and its metabolite hydroxyitraconazole using primary human hepatocytes.

  Pharmacology 20030401

• A new isoquinolinone derivative with noble vasorelaxation activity.

  Pharmacology 20030401

• Lafutidine vs cimetidine to decrease gastric fluid acidity and volume in children.

  Canadian journal of anaesthesia = Journal canadien d'anesthesie 20030401

• Rat organic anion transporter 3 (rOAT3) is responsible for brain-to-blood efflux of homovanillic acid at the abluminal membrane of brain capillary endothelial cells.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20030401

• Evaluation of P-glycoprotein-mediated renal drug interactions in an MDR1-MDCK model.

  Pharmacotherapy 20030401

• Fluorescent substrates of sister-P-glycoprotein (BSEP) evaluated as markers of active transport and inhibition: evidence for contingent unequal binding sites.

  Pharmaceutical research 20030401

• Noninvasive characterization of regional variation in drug transport into human stratum corneum in vivo.

  Pharmaceutical research 20030401

• Evaluation of the antiulcerogenic activity of violacein and its modulation by the inclusion complexation with beta-cyclodextrin.

  Canadian journal of physiology and pharmacology 20030401

• Effects of histamine and cholinergic systems on memory retention of passive avoidance learning in rats.

  European journal of pharmacology 20030328

• Increased plasma concentration and brain penetration of methamphetamine in behaviorally sensitized rats.

  European journal of pharmacology 20030307

• Transport of cimetidine by flounder and human renal organic anion transporter 1.

  American journal of physiology. Renal physiology 20030301

• Effect of histamine on phasic and tonic contractions of isolated uterine tissue from pregnant women.

  American journal of obstetrics and gynecology 20030301

• Intravenous proton-pump inhibitors versus H2-antagonists for treatment of GI bleeding.

  The Annals of pharmacotherapy 20030301

• [Effects of central histaminergic receptor activation on carotid sinus baroreceptor reflex resetting in stressed rats].

  Sheng li xue bao : [Acta physiologica Sinica] 20030225

• Helicobacter pylori in cathartic stools of subjects with and without cimetidine-induced hypochlorhydria.

  Journal of medical microbiology 20030201

• Cimetidine therapy for epidermodysplasia verruciformis.

  Journal of the American Academy of Dermatology 20030201

• Weekly 1-h paclitaxel infusion in patients with recurrent endometrial cancer: a preliminary study.

  International journal of clinical oncology 20030201

• Histaminergic modulation of the intact respiratory network of adult mice.

  Pflugers Archiv : European journal of physiology 20030201

• Characteristics of attenuating effects of rebamipide, an anti-ulcer agent, on oxidative burst of human neutrophils.

  Journal of pharmacological sciences 20030201

• Functional identification of epithelial and smooth muscle histamine-dependent relaxing mechanisms in the bovine trachea, but not in bronchi.

  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20030101

• Constitutive nitric oxide synthase inhibition combined with histamine and serotonin receptor blockade improves the initial ovalbumin-induced arterial hypotension but decreases the survival time in brown norway rats anaphylactic shock.

  Shock (Augusta, Ga.) 20030101

• The cimetidine protocol: a convenient, accurate, and inexpensive way to measure glomerular filtration rate.

  Pediatric nephrology (Berlin, Germany) 20030101

• Prevention and treatment of stress ulcers in critically ill patients.

  Seminars in gastrointestinal disease 20030101

• The effect of commonly used drugs on angiogenesis.

  Anticancer research 20030101

• Gastroesophageal reflux and histamine2 antagonists.

  Neonatal network : NN 20030101

• Inhibition of adhesion breast cancer cells by anticoagulant drugs and cimetidine.

  Neoplasma 20030101

• Cimetidine reduces impairment of cellular immunity after transcatheter arterial embolization in patients with hepatocellular carcinoma.

  Hepato-gastroenterology 20030101

• Cimetidine for chronic calcifying tendinitis of the shoulder.

  Regional anesthesia and pain medicine 20030101

• Role of cytochrome P450 2B1 in puromycin aminonucleoside-induced cytotoxicity to glomerular epithelial cells.

  Nephron. Experimental nephrology 20030101

• Determination of theophylline clearance after cimetidine infusion in critically ill patients.

  Journal of infusion nursing : the official publication of the Infusion Nurses Society 20030101

• Activity of cathepsin B, D and L in rat cerebrum after cimetidine and famotidine administration.

  Acta physiologica Hungarica 20030101

• Drug interactions of clinical significance for the dermatologist: recognition and avoidance.

  American journal of clinical dermatology 20030101

• [Pharmacotherapy in complex treatment of ulcerous stenosis].

  Vestnik khirurgii imeni I. I. Grekova 20030101

• Human organic anion transporter 3 (hOAT3) can operate as an exchanger and mediate secretory urate flux.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20030101

• [Comparative analysis of the influence of food and cimetidine in plasma levels of praziquantel].

  Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion 20030101

• Evidence for the involvement of a macrophage-derived chemotactic mediator in the neutrophil recruitment induced by staphylococcal enterotoxin B in mice.

  Toxicon : official journal of the International Society on Toxinology 20021201

• A new approach for high-pressure freezing of primary culture cells: the fine structure and stimulation-associated transformation of cultured rabbit gastric parietal cells.

  Journal of microscopy 20021201

• Pharmacokinetics of saquinavir co-administered with cimetidine.

  The Journal of antimicrobial chemotherapy 20021201

• Histamine H1 receptors in rat dorsal raphe nucleus: pharmacological characterisation and linking to increased neuronal activity.

  Brain research 20021108

• Possible role of histamine (H1- and H2-) receptors in the regulation of meningeal blood flow.

  British journal of pharmacology 20021101

• Activation of the extraneuronal monoamine transporter (EMT) from rat expressed in 293 cells.

  British journal of pharmacology 20021101

• Effects of histamine H(2)-receptor antagonists on human plasma levels of calcitonin gene-related peptide, substance P and vasoactive intestinal peptide.

  The Journal of pharmacy and pharmacology 20021101

• [Paclitaxel hypersensitivity reactions in patients with advanced ovarian carcinoma].

  Ginekologia polska 20021101

• Histamine H(2) receptor-mediated modulation of local cytokine expression in a mouse experimental tumor model.

  Biochemical and biophysical research communications 20021011

• Cimetidine prevents suppression of delayed hypersensitivity in an animal model of haemorrhagic shock.

  Injury 20021001

• Histamine h(4) and h(2) receptors control histamine-induced interleukin-16 release from human CD8(+) T cells.

  The Journal of pharmacology and experimental therapeutics 20021001

• Inhibition of improgan antinociception by the cannabinoid (CB)(1) antagonist N-(piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716A): lack of obligatory role for endocannabinoids acting at CB(1) receptors.

  The Journal of pharmacology and experimental therapeutics 20021001

• Gastroprotective effect of beta3 adrenoreceptor agonists ZD 7114 and CGP 12177A in rats.

  Pharmacological research 20021001

• Inhibition of zaleplon metabolism by cimetidine in the human liver: in vitro studies with subcellular fractions and precision-cut liver slices.

  Xenobiotica; the fate of foreign compounds in biological systems 20021001

• Murine tumor necrosis factor-alpha sensitizes plasma corticosterone activity and the manifestation of shock: modulation by histamine.

  Journal of neuroimmunology 20021001

• Histamine release in mesenteric traction syndrome during abdominal aortic aneurysm surgery: prophylaxis with H1 and H2 antihistamines.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20021001

• Influence of different chemicals on MDR-1 P-glycoprotein expression and activity in the HK-2 proximal tubular cell line.

  Toxicology and applied pharmacology 20020901

• Effect of essential oil obtained from Croton cajucara Benth. on gastric ulcer healing and protective factors of the gastric mucosa.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20020901

• Histaminergic modulation of stress-induced analgesia and cognitive dysfunction.

  Methods and findings in experimental and clinical pharmacology 20020901

• Functional characterization of mouse cation transporter mOCT2 compared with mOCT1.

  Biochemical and biophysical research communications 20020823

• NHE blockade inhibits chemokine production and NF-kappaB activation in immunostimulated endothelial cells.

  American journal of physiology. Cell physiology 20020801

• Down-regulation of rat organic cation transporter rOCT2 by 5/6 nephrectomy.

  Kidney international 20020801

• Involvement of organic cation transporter 1 in hepatic and intestinal distribution of metformin.

  The Journal of pharmacology and experimental therapeutics 20020801

• The control effect of histamine on body temperature and respiratory function in IgE-dependent systemic anaphylaxis.

  The Journal of allergy and clinical immunology 20020801

• [What is important in treating elderly with H2 receptor antagonists].

  Nihon rinsho. Japanese journal of clinical medicine 20020801

• [QOL and the older people with peptic ulcer].

  Nihon rinsho. Japanese journal of clinical medicine 20020801

• Cold induces catalytic iron release of cytochrome P-450 origin: a critical step in cold storage-induced renal injury.

  American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20020801

• Physicochemical properties of amorphous salt of cimetidine and diflunisal system.

  International journal of pharmaceutics 20020725

• Role of aromatic transmembrane residues of the organic anion transporter, rOAT3, in substrate recognition.

  Biochemistry 20020716

• Na+/H+ exchanger blockade inhibits enterocyte inflammatory response and protects against colitis.

  American journal of physiology. Gastrointestinal and liver physiology 20020701

• Isolation, characterization and differential gene expression of multispecific organic anion transporter 2 in mice.

  Molecular pharmacology 20020701

• cDNA cloning, functional characterization, and tissue distribution of an alternatively spliced variant of organic cation transporter hOCT2 predominantly expressed in the human kidney.

  Journal of the American Society of Nephrology : JASN 20020701

• Options for pharmacological management of obesity in patients treated with atypical antipsychotics.

  International clinical psychopharmacology 20020701

• Impact of reference-based pricing for histamine-2 receptor antagonists and restricted access for proton pump inhibitors in British Columbia.

  CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20020625

• The human organic cation transporter (hOCT2) recognizes the degree of substrate ionization.

  The Journal of biological chemistry 20020621

• Effects of N-alpha-methyl-histamine on human H(2) receptors expressed in CHO cells.

  Gut 20020601

• Cockcroft-Gault equation and estimation of creatinine clearance.

  The American journal of medicine 20020601

• Histamine H(2) -like receptors in chick cerebral cortex: effects on cyclic AMP synthesis and characterization by [(3) H]tiotidine binding.

  Journal of neurochemistry 20020601

• Acute pancreatitis and the role of histamine-2 receptor antagonists: a meta-analysis of randomized controlled trials of cimetidine.

  European journal of gastroenterology & hepatology 20020601

• Antiulcerogenic activity of some sesquiterpene lactones isolated from Artemisia annua.

  Planta medica 20020601

• Cimetidine and a tamoxifen derivate reduce tumour formation in SCID mice xenotransplanted with a human melanoma cell line.

  Melanoma research 20020601

• Fever and sweats in the patient with advanced cancer.

  Hematology/oncology clinics of North America 20020601

• Influence of aging on gastric ulcer healing activities of cimetidine and omeprazole.

  European journal of pharmacology 20020531

• Chemiluminescence associated with the oxidative metabolism of salicylic acid in rat liver microsomes.

  Chemico-biological interactions 20020520

• Regulation of phospholipase C activation by the number of H(2) receptors during Ca(2+)-induced differentiation of mouse keratinocytes.

  Biochemical pharmacology 20020515

• Experimental anxiety induced by histaminergics in mast cell-deficient and congenitally normal mice.

  Pharmacology, biochemistry, and behavior 20020501

• Expression and functional characterization of rat organic anion transporter 3 (rOat3) in the choroid plexus.

  Molecular pharmacology 20020501

• Vitamin B(12) deficiency associated with histamine(2)-receptor antagonists and a proton-pump inhibitor.

  The Annals of pharmacotherapy 20020501

• Binding of [(3)H]prazosin to alpha(1A)- and alpha(1B)-adrenoceptors, and to a cimetidine-sensitive non-alpha(1) binding site in rat kidney membranes.

  Naunyn-Schmiedeberg's archives of pharmacology 20020501

• Derivatives of dehydrocrotonin, a diterpene lactone isolated from Croton cajucara: cytotoxicity in rat cultured hepatocytes and in V79 cells.

  Human & experimental toxicology 20020501

• Persistent molluscum contagiosum. Case study in a 6-year-old girl with asthma and eczema.

  Advance for nurse practitioners 20020501

• Susceptibility of the H2-receptor antagonists cimetidine, famotidine and nizatidine, to metabolism by the gastrointestinal microflora.

  International journal of pharmaceutics 20020426

• Cimetidine enhances the plasma praziquantel concentration and treatment efficacy against Microcotyle sebastis in cultured rockfish Sebastes schlegeli.

  Diseases of aquatic organisms 20020424

• Cimetidine modulates the antigen presenting capacity of dendritic cells from colorectal cancer patients.

  British journal of cancer 20020422

• Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

  The Journal of biological chemistry 20020419

• The effect of multiple doses of cimetidine on the steady-state pharmacokinetics of quetiapine in men with selected psychotic disorders.

  Journal of clinical psychopharmacology 20020401

• Helicobacter pylori eradication in patients on long-term H2 receptor antagonists. Economic and symptomatic benefits. A large prospective study in primary care.

  Helicobacter 20020401

• H(2) antagonist-induced thrombocytopenia: is this a real phenomenon?

  Intensive care medicine 20020401

• A review of epidemiological studies on cancer in relation to the use of anti-ulcer drugs.

  European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 20020401

• Mouse mammary epithelial cells bear histamine receptors.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20020401

• The initial inositol 1,4,5-trisphosphate response induced by histamine is strongly amplified by Ca(2+) release from internal stores in smooth muscle.

  Cell calcium 20020401

• Effects of H(2)-receptor antagonists on dapsone-induced methaemoglobinaemia in rats.

  Pharmacological research 20020401

• Cimetidine improves prediction of the glomerular filtration rate by the Cockcroft-Gault formula in renal transplant recipients.

  Transplantation 20020315

• Reduction of toxic metabolite formation of acetaminophen.

  Biochemical and biophysical research communications 20020308

• Induction of cardiac cytochrome p450 in cocaine-treated mice.

  Experimental biology and medicine (Maywood, N.J.) 20020301

• Endogenous mast cell degranulation modulates cervical contractility in the guinea pig.

  American journal of obstetrics and gynecology 20020301

• Serosal application of Ba(2+) induces oscillatory chloride secretion via activation of submucosal cholinergic neurones in guinea-pig distal colon.

  Acta physiologica Scandinavica 20020301

• Anti-ulcerogenic and analgesic activities of the leaves of Wilbrandia ebracteata in mice.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20020301

• Protective effects of cimetidine on radiation-induced micronuclei and apoptosis in human peripheral blood lymphocytes.

  Free radical research 20020301

• Effect of grapefruit juice or cimetidine coadministration on albendazole bioavailability.

  The American journal of tropical medicine and hygiene 20020301

• Characterization of histamine H(2)-like receptors in duck cerebral cortical membranes by [(3)H]tiotidine binding.

  Neuroscience letters 20020222

• Interaction of cimetidine with P450 in a mouse model of hepatocarcinogenesis initiation.

  British journal of cancer 20020212

• The effects of cimetidine and antacid on the pharmacokinetic profile of sildenafil citrate in healthy male volunteers.

  British journal of clinical pharmacology 20020201

• Gastro-oesophageal reflux disease in obesity: pathophysiological and therapeutic considerations.

  Obesity reviews : an official journal of the International Association for the Study of Obesity 20020201

• Cimetidine in colorectal cancer--are the effects immunological or adhesion-mediated?

  British journal of cancer 20020121

• Cimetidine increases survival of colorectal cancer patients with high levels of sialyl Lewis-X and sialyl Lewis-A epitope expression on tumour cells.

  British journal of cancer 20020121

• Assessment of the relationship between hyperalgesia and peripheral inflammation in magnesium-deficient rats.

  Life sciences 20020118

• The use of solution calorimetry with micellar solvent systems for the detection of polymorphism.

  International journal of pharmaceutics 20020114

• Anti-Helicobacter pylori agents. 5. 2-(Substituted guanidino)-4-arylthiazoles and aryloxazole analogues.

  Journal of medicinal chemistry 20020103

• The anti-influenza drug oseltamivir exhibits low potential to induce pharmacokinetic drug interactions via renal secretion-correlation of in vivo and in vitro studies.

  Drug metabolism and disposition: the biological fate of chemicals 20020101

• Cimetidine administration and tubular creatinine secretion in patients with compensated cirrhosis.

  Clinical science (London, England : 1979) 20020101

• Two cDNAs coding for histamine-gated ion channels in D. melanogaster.

  Nature neuroscience 20020101

• Variability in cimetidine absorption and plasma double peaks following oral administration in the fasted state in humans: correlation with antral gastric motility.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20020101

• Short-term prevention of osteoclastic resorption and osteopenia in ovariectomized rats treated with the H(2) receptor antagonist cimetidine.

  Bone 20020101

• Use of 5-[(76)Br]bromo-2'-fluoro-2'-deoxyuridine as a ligand for tumour proliferation: validation in an animal tumour model.

  European journal of nuclear medicine and molecular imaging 20020101

• Effects of the prenatal administration of cimetidine on testicular descent and genital differentiation in rats.

  Surgery 20020101

• Uptake of lamivudine by rat renal brush border membrane vesicles.

  The Journal of pharmacy and pharmacology 20020101

• Decrease of intragastric acidity in healthy subjects dosed with ranitidine 75 mg, cimetidine 200 mg, or placebo.

  Digestive diseases and sciences 20020101

• Histamine-induced IL-6 and IL-8 production are differentially modulated by IFN-gamma and IL-4 in human keratinocytes.

  Journal of dermatological science 20020101

• Pharmacologic interventions in nuclear radiology: indications, imaging protocols, and clinical results.

  Radiographics : a review publication of the Radiological Society of North America, Inc 20020101

• Could cimetidine be used as a booster?

  TreatmentUpdate 20020101

• In vivo effect of diallyl sulfide and cimetidine on phenacetin metabolism and bioavailability in rat.

  Acta biochimica Polonica 20020101

• Premedication strategy for weekly paclitaxel.

  Cancer investigation 20020101

• In vivo effect of 5- and 8-methoxypsoralens and cimetidine on R,S-warfarin metabolism in rat.

  Journal of applied toxicology : JAT 20020101

• Determination of cimetidine, famotidine, and ranitidine hydrochloride in the presence of their sulfoxide derivatives in pure and dosage forms by high-performance thin-layer chromatography and scanning densitometry.

  Journal of AOAC International 20020101

• Different h2 receptor antihistamines dissimilarly retard the growth of xenografted human melanoma cells in immunodeficient mice.

  Cell biology international 20020101

• Randomized trial of single agent paclitaxel given weekly versus every three weeks and with peroral versus intravenous steroid premedication to patients with ovarian cancer previously treated with platinum.

  Acta oncologica (Stockholm, Sweden) 20020101

• Effects of the anti-ulcer agents ecabet sodium, cimetidine and sucralfate on acetylsalicylic acid-induced gastric mucosal damage deteriorated by renal failure in rats.

  Arzneimittel-Forschung 20020101

• Effects of three H2-receptor antagonists (cimetidine, famotidine, ranitidine) on serum gastrin level.

  International journal of clinical pharmacology research 20020101

• A role for spinal, but not supraspinal, alpha(2) adrenergic receptors in the actions of improgan, a powerful, non-opioid analgesic.

  Brain research 20011227

• Similar apparent constitutive activity of human histamine H(2)-receptor fused to long and short splice variants of G(salpha).

  The Journal of pharmacology and experimental therapeutics 20011201

• Distinct interaction of human and guinea pig histamine H2-receptor with guanidine-type agonists.

  Molecular pharmacology 20011201

• Enhancement by histamine of vascular endothelial growth factor production in granulation tissue via H(2) receptors.

  British journal of pharmacology 20011201

• Gastroesophageal reflux in infants and children.

  American family physician 20011201

• The influence of commonly prescribed synthetic drugs for peptic ulcer on the pharmacokinetic fate of glycyrrhizin from Shaoyao-Gancao-tang.

  Biological & pharmaceutical bulletin 20011201

• Is the intestinal tract a portal of entry for Acanthamoeba infection?

  Journal of the Egyptian Society of Parasitology 20011201

• Comparative studies on in vitro methods for evaluating in vivo function of MDR1 P-glycoprotein.

  Pharmaceutical research 20011201

• Optimization of the single-day praziquantel therapy for neurocysticercosis.

  Neurology 20011127

• Histamine deficiency induces tissue-specific down-regulation of histamine H2 receptor expression in histidine decarboxylase knockout mice.

  FEBS letters 20011116

• Absence of mast cell involvement in active systemic anaphylaxis in rats.

  European journal of pharmacology 20011102

• The kinetics, function, and regulation of P-selectin expressed by human brain microvessel endothelial cells in primary culture.

  Microvascular research 20011101

• Release of non-neuronal acetylcholine from the isolated human placenta is mediated by organic cation transporters.

  British journal of pharmacology 20011101

• The use of on-line and off-line chromatographic extraction techniques coupled with mass spectrometry for support of in vivo and in vitro assays in drug discovery.

  Current topics in medicinal chemistry 20011101

• The stomach divalent ion-sensing receptor scar is a modulator of gastric acid secretion.

  The Journal of biological chemistry 20011026

• [Protein-losing syndrome of the gastrointestinal tract].

  Deutsche medizinische Wochenschrift (1946) 20011026

• Effect of orally administered cimetidine and ranitidine on abomasal luminal pH in clinically normal milk-fed calves.

  American journal of veterinary research 20011001

• HT29-MTX and Caco-2/TC7 monolayers as predictive models for human intestinal absorption: role of the mucus layer.

  Journal of pharmaceutical sciences 20011001

• Characterization of ochratoxin A transport by human organic anion transporters.

  Life sciences 20010921

• Recombinant Semliki Forest virus for over-expression and pharmacological characterisation of the histamine H(2) receptor in mammalian cells.

  European journal of pharmacology 20010914

• Antiulcerogenic and analgesic effects of Maytenus aquifolium, Sorocea bomplandii and Zolernia ilicifolia.

  Journal of ethnopharmacology 20010901

• Treatment of non-ulcer dyspepsia: a meta-analysis of placebo-controlled prospective studies.

  Scandinavian journal of gastroenterology 20010901

• H2-receptor antagonists in the treatment of functional (nonulcer) dyspepsia: a meta-analysis of randomized controlled clinical trials.

  Alimentary pharmacology & therapeutics 20010901

• Delirium following a switch from cimetidine to famotidine.

  The Annals of pharmacotherapy 20010901

• Dapsone in rosacea fulminans.

  Journal of the European Academy of Dermatology and Venereology : JEADV 20010901

• Effects of histamine and related compounds on the differentiation of HL-60-Eo cells into eosinophils.

  Methods and findings in experimental and clinical pharmacology 20010901

• Simple high-performance liquid chromatographic method to analyze serum creatinine has several advantages over the Jaffé picric acid reaction as demonstrated with a cimetidine dose response in rhesus monkeys.

  Journal of chromatography. B, Biomedical sciences and applications 20010815

• Independent organic cation transport activity of Na(+)-L-carnitine cotransport system in LLC-PK(1) cells.

  American journal of physiology. Renal physiology 20010801

• Cimetidine in painful bladder syndrome: a histopathological study.

  BJU international 20010801

• The effects of histamine and its antagonists on the cochlear microphonic and the compound action potential of the guinea pig.

  Auris, nasus, larynx 20010801

• A randomised controlled trial of four management strategies for dyspepsia: relationships between symptom subgroups and strategy outcome.

  The British journal of general practice : the journal of the Royal College of General Practitioners 20010801

• Creatinine excretion rates for renal clearance studies.

  Pediatric nephrology (Berlin, Germany) 20010801

• Head-column field-amplified sample stacking in capillary electrophoresis for the determination of cimetidine, famotidine, nizatidine, and ranitidine-HCl in plasma.

  Electrophoresis 20010801

• Simultaneous determination of cimetidine, famotidine, nizatidine, and ranitidine in tablets by capillary zone electrophoresis.

  Electrophoresis 20010801

• Increased histidine decarboxylase expression during in vitro monocyte maturation; a possible role of endogenously synthesised histamine in monocyte/macrophage differentiation.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20010801

• ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.

  Journal of medicinal chemistry 20010719

• Antiulcer action of the hydroalcoholic extract and fractions of Davilla rugosa Poiret in the rat.

  Journal of ethnopharmacology 20010701

• Cimetidine-induced dystonic reaction.

  The Journal of emergency medicine 20010701

• Proton pump inhibitors versus H2-antagonists: a meta-analysis of their efficacy in treating bleeding peptic ulcer.

  Alimentary pharmacology & therapeutics 20010701

• Effect of cimetidine on pharmacokinetics of orally administered cyclosporine in healthy dogs.

  American journal of veterinary research 20010701

• A practical approach to glomerular filtration rate measurements: creatinine clearance estimation using cimetidine.

  Annals of clinical and laboratory science 20010701

• The effect of betahistine on vestibular habituation: comparison of rotatory and sway habituation training.

  Acta oto-laryngologica 20010701

• Experimental and computational screening models for the prediction of intestinal drug absorption.

  Journal of medicinal chemistry 20010607

• Comparison of in situ gelling formulations for the oral delivery of cimetidine.

  International journal of pharmaceutics 20010604

• Medical therapy in interstitial cystitis: the essex experience.

  Urology 20010601

• Localized heat urticaria: a clinical study using laser Doppler flowmetry.

  Journal of dermatological science 20010601

• Accurate mass liquid chromatography/mass spectrometry on quadrupole orthogonal acceleration time-of-flight mass analyzers using switching between separate sample and reference sprays. 2. Applications using the dual-electrospray ion source.

  Analytical chemistry 20010601

• Nicotinamide adenine dinucleotide-dependent retinoic acid formation from retinol in the human gastric mucosa: inhibition by ethanol, acetaldehyde, and H2 blockers.

  Alcoholism, clinical and experimental research 20010601

• Human jejunal permeability of two polar drugs: cimetidine and ranitidine.

  Pharmaceutical research 20010601

• Arginine 454 and lysine 370 are essential for the anion specificity of the organic anion transporter, rOAT3.

  Biochemistry 20010508

• Histamine H3 receptor-mediated inhibition of sympathetically evoked mydriasis in rats.

  European journal of pharmacology 20010504

• Significance of GABAergic systems in the action of improgan, a non-opioid analgesic.

  Life sciences 20010504

• Identification and characterization of human organic anion transporter 3 expressing predominantly in the kidney.

  Molecular pharmacology 20010501

• Metabolism of amiodarone (Part III): identification of rabbit cytochrome P450 isoforms involved in the hydroxylation of mono-N-desethylamiodarone.

  Xenobiotica; the fate of foreign compounds in biological systems 20010501

• Inhibition of effects of endogenously synthesized histamine disturbs in vitro human dendritic cell differentiation.

  Immunology letters 20010402

• Prediction of midazolam-CYP3A inhibitors interaction in the human liver from in vivo/in vitro absorption, distribution, and metabolism data.

  Drug metabolism and disposition: the biological fate of chemicals 20010401

• Effects of vitamins and common drugs on reduction of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in rat microsomes.

  Archives of physiology and biochemistry 20010401

• High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes.

  Journal of medicinal chemistry 20010315

• Haloperidol-stomach lesions attenuation by pentadecapeptide BPC 157, omeprazole, bromocriptine, but not atropine, lansoprazole, pantoprazole, ranitidine, cimetidine and misoprostol in mice.

  Life sciences 20010309

• Treatment of Microcotyle sebastis infestation in cultured rockfish Sebastes schlegeli by oral administration of praziquantel in combination with cimetidine.

  Diseases of aquatic organisms 20010309

• Effect of cimetidine on intratumoral cytokine expression in an experimental tumor.

  Biochemical and biophysical research communications 20010301

• Prevention of vinorelbine phlebitis with cimetidine. A two-step design study.

  Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20010301

• Gastroprotective effect of aparisthman, a diterpene isolated from Aparisthmium cordatum, on experimental gastric ulcer models in rats and mice.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20010301

• Stimulation by nitric oxide of gastric acid secretion in bullfrog fundic mucosa in vitro.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20010301

• Cimetidine inhibits production of interferon gamma and tumor necrosis factor alpha by splenocytes in aplastic anemic mice.

  Acta pharmacologica Sinica 20010301

• In vitro/in vivo scaling of alprazolam metabolism by CYP3A4 and CYP3A5 in humans.

  Biopharmaceutics & drug disposition 20010301

• Regulation of parasympathetic neurons by mast cells and histamine in the guinea pig heart.

  Autonomic neuroscience : basic & clinical 20010220

• [About paracetamol again].

  Orvosi hetilap 20010218

• The prescribing of acid suppressants prior to the endoscopic diagnosis of Barrett's oesophagus and oesophagitis.

  Alimentary pharmacology & therapeutics 20010201

• Acral purpuric plaques in a woman with asthma: a case of allergic granulomatosis angiitis.

  Cutis 20010201

• The characterisation and uptake of paraquat in cultured baboon kidney proximal tubule cells (bPTC).

  Human & experimental toxicology 20010201

• Characterization of histamine-induced increases in intracellular free Ca2+ concentrations in Chang liver cells.

  Journal of receptor and signal transduction research 20010201

• Approaches to healing and prophylaxis of nonsteroidal anti-inflammatory drug-associated ulcers.

  The American journal of medicine 20010108

• Interactions between cimetidine, nitrofurantoin, and probenecid active transport into rat milk.

  The Journal of pharmacology and experimental therapeutics 20010101

• Cytochrome P-450 as a source of catalytic iron in minimal change nephrotic syndrome in rats.

  American journal of physiology. Renal physiology 20010101

• Effect of organic cations on the renal tubular secretion of pseudoephedrine in the rat.

  Clinical and experimental pharmacology & physiology 20010101

• The major role of peripheral release of histamine and 5-hydroxytryptamine in formalin-induced nociception.

  Neuroscience 20010101

• Role of mast cells in zymosan-induced peritoneal inflammation in Balb/c and mast cell-deficient WBB6F1 mice.

  Journal of leukocyte biology 20010101

• Morphological alterations and intratubular lipid inclusions as indicative of spermatogenic damage in cimetidine-treated rats.

  Archives of andrology 20010101

• Nephrotoxicity and hepatotoxicity of histamine H2 receptor antagonists.

  Drug safety 20010101

• Inhibition of drug metabolism in human liver microsomes by nizatidine, cimetidine and omeprazole.

  Xenobiotica; the fate of foreign compounds in biological systems 20010101

• Burn wound itch control using H1 and H2 antagonists.

  The Journal of burn care & rehabilitation 20010101

• Cimetidine and levamisole versus cimetidine alone for recalcitrant warts in children.

  Pediatric dermatology 20010101

• Evaluation of the effects of nicorandil on experimentally induced gastric ulcers.

  Pharmacology 20010101

• Nutritional effects of surgical and medical treatment for short bowel syndrome.

  JPEN. Journal of parenteral and enteral nutrition 20010101

• Effect of phenobarbital and spironolactone treatment on the oxidative metabolism of antipyrine by rat liver microsomes.

  Polish journal of pharmacology 20010101

• Potent and long-lasting action of lafutidine on the human histamine H(2) receptor.

  Digestion 20010101

• Active transport of nitrofurantoin into rat milk.

  Advances in experimental medicine and biology 20010101

• Influence of lysine on cimetidine uptake and on excretion of cimetidine by the rat mammary gland.

  Advances in experimental medicine and biology 20010101

• G649, an allelic variant of the human H2 receptor with low basal activity, is resistant to upregulation upon antagonist exposure.

  The pharmacogenomics journal 20010101

• [Gastroesophageal reflux disease in pregnancy].

  Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20010101

• Transepithelial resistance can be regulated by the intestinal brush-border Na(+)/H(+) exchanger NHE3.

  American journal of physiology. Cell physiology 20001201

• Histamine up-regulates phosphodiesterase 4 activity and reduces prostaglandin E2-inhibitory effects in human neutrophils.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20001101

• The involvement of flavin-containing monooxygenase but not CYP3A4 in metabolism of itopride hydrochloride, a gastroprokinetic agent: comparison with cisapride and mosapride citrate.

  Drug metabolism and disposition: the biological fate of chemicals 20001001

• Identification of a histamine H(3)-like receptor in the zebrafish (Danio rerio) brain.

  Journal of neurochemistry 20000801

• Cimetidine and a delayed hypersensitivity reaction.

  Clinics in podiatric medicine and surgery 20000401

• Histamine and histamine-receptor antagonists modify gene expression and biosynthesis of interferon gamma in peripheral human blood mononuclear cells and in CD19-depleted cell subsets.

  Immunology letters 19991101

• Drug-associated acute pancreatitis: twenty-one years of spontaneous reporting in The Netherlands.

  The American journal of gastroenterology 19990901

• Selective substrates for non-neuronal monoamine transporters.

  Molecular pharmacology 19990701

• Cimetidine-associated optic neuropathy.

  European neurology 19990701

• Molecular cloning and characterization of a new multispecific organic anion transporter from rat brain.

  The Journal of biological chemistry 19990507

• A case of cimetidine-induced acute tubulointerstitial nephritis associated with antineutrophil cytoplasmic antibody.

  American journal of kidney diseases : the official journal of the National Kidney Foundation 19990201

• Molecular identification of the corticosterone-sensitive extraneuronal catecholamine transporter.

  Nature neuroscience 19980901

• Constitutive activity and structural instability of the wild-type human H2 receptor.

  Journal of neurochemistry 19980801

• Functional characterization of an organic cation transporter (hOCT1) in a transiently transfected human cell line (HeLa).

  The Journal of pharmacology and experimental therapeutics 19980701

• Heterologous expression of rat epitope-tagged histamine H2 receptors in insect Sf9 cells.

  British journal of pharmacology 19971101

• Efficacy of a selective histamine H2 receptor agonist, dimaprit, in experimental models of endotoxin shock and hepatitis in mice.

  European journal of pharmacology 19970312

• Effect of the oral anti-ulcer agent, cimetidine, on HIV type 1 replication.

  AIDS research and human retroviruses 19970301

• Neurobehavioral syndrome induced by H2-receptor blocker withdrawal: possible role of prolactin.

  Clinical neuropharmacology 19970201

• [Hemolytic anemia and thrombocytopenia induced by cimetidine: recurrence with ranitidine administration].

  [Rinsho ketsueki] The Japanese journal of clinical hematology 19970201

• Effect of adenosine and histamine receptor stimulation on canine histamine release to pentagastrin.

  Digestion 19970101

• Lansoprazole compared with histamine2-receptor antagonists in healing gastric ulcers: a meta-analysis.

  Clinical therapeutics 19970101

• Coma from the health food store: interaction between kava and alprazolam.

  Annals of internal medicine 19961201

• The role of histaminergic-noradrenergic axis in naloxone-induced withdrawal symptoms in mice.

  Pharmacology, biochemistry, and behavior 19960901

• Effect of histamine and the H2 antagonist cimetidine on the growth and migration of human neoplastic glia.

  Neuropathology and applied neurobiology 19960801

• Influence of H2-receptor- and proton pump inhibitors on some functions of the oxydative and conjugative drug metabolism.

  Die Pharmazie 19960701

• Inverse agonism of histamine H2 antagonist accounts for upregulation of spontaneously active histamine H2 receptors.

  Proceedings of the National Academy of Sciences of the United States of America 19960625

• Induction of CYP1A1 gene by benzimidazole derivatives during Caco-2 cell differentiation. Evidence for an aryl-hydrocarbon receptor-mediated mechanism.

  European journal of biochemistry 19960501

• Selective effect of levocabastine on histamine receptor and histamine release from human leukocytes and guinea pig isolated tissue.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 19960401

• Neurotoxic convulsions induced by histamine H2 receptor antagonists in mice.

  Toxicology and applied pharmacology 19960201

• New sigma and 5-HT1A receptor ligands: omega-(tetralin-1-yl)-n-alkylamine derivatives.

  Journal of medicinal chemistry 19960105

• The effect of histamine type 2 receptor antagonists on human immunodeficiency virus (HIV) replication: identification of a new class of antiviral agents.

  Life sciences 19960101

• Rebamipide, novel prostaglandin-inducer accelerates healing and reduces relapse of acetic acid-induced rat gastric ulcer. Comparison with cimetidine.

  Digestive diseases and sciences 19951101

• Parkinsonism associated with fluoxetine and cimetidine: a case report.

  Journal of geriatric psychiatry and neurology 19951001

• Effect of anti-ulcer drugs on DNA synthesis in adult normal human hepatocytes in culture.

  Hepatology (Baltimore, Md.) 19950901

• Atracurium and status epilepticus?

  Critical care medicine 19950801

• Treatment of HIV-associated Kaposi's sarcoma with paclitaxel.

  Lancet (London, England) 19950701

• Gynecomastia and sexual disorders after the administration of omeprazole.

  The American journal of gastroenterology 19950601

• Central nervous system activity of Rhazya stricta (Decne) in mice.

  Clinical and experimental pharmacology & physiology 19950401

• Cimetidine improves the therapeutic/toxic ratio of dapsone in patients on chronic dapsone therapy.

  The British journal of dermatology 19950201

• Erythromycin deafness and cimetidine treatment.

  BMJ (Clinical research ed.) 19941217

• Genotoxicity of the alkenylbenzenes alpha- and beta-asarone, myristicin and elimicin as determined by the UDS assay in cultured rat hepatocytes.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 19940301

• Hepatitis following treatments with famotidine and then cimetidine.

  The Annals of pharmacotherapy 19940101

• Cimetidine-induced seizures in mice. Antagonism by some GABAergic agents.

  Biochemical pharmacology 19931214

• The effect of cimetidine on the pharmacokinetics of single oral doses of alfuzosin.

  International journal of clinical pharmacology, therapy, and toxicology 19931101

• Public health problems and the rapid estimation of the size of the population at risk. Torsades de pointes and the use of terfenadine and astemizole in The Netherlands.

  Pharmacy world & science : PWS 19931015

• Ranitidine-associated interstitial nephritis and Fanconi syndrome.

  American journal of kidney diseases : the official journal of the National Kidney Foundation 19930801

• Ranitidine-induced acute interstitial nephritis with epithelial cell foot process fusion.

  American journal of kidney diseases : the official journal of the National Kidney Foundation 19930801

• Sinus arrest associated with continuous-infusion cimetidine.

  Pharmacotherapy 19930101

• [Cimetidine hepatitis].

  Harefuah 19921215

• [A case of acute interstitial nephritis and nonoliguria acute renal failure induced by cimetidine].

  Nihon Jinzo Gakkai shi 19921101

• Cimetidine-dobutamine interaction?

  Anaesthesia 19921101

• Polyuria and weight-loss associated with cimetidine.

  Postgraduate medical journal 19920901

• Pharmacokinetic profile of nicorandil in humans: an overview.

  Journal of cardiovascular pharmacology 19920101

• Decreased histamine H1 receptors in the frontal cortex of brains from patients with chronic schizophrenia.

  Biological psychiatry 19910815

• Diphenhydramine prevents the haemodynamic changes of cimetidine in ICU patients.

  Canadian journal of anaesthesia = Journal canadien d'anesthesie 19910301

• Cimetidine inhibits catechol estrogen metabolism in women.

  Metabolism: clinical and experimental 19910201

• Nifedipine versus cimetidine in prevention of stress-induced gastric ulcers in rats.

  European journal of pharmacology 19910103

• Effects of antihistaminics on locomotor activity in mice. Comparison with opiate and amphetamine-induced hyperactivity.

  General pharmacology 19910101

• Catalytic activities of human liver cytochrome P-450 IIIA4 expressed in Saccharomyces cerevisiae.

  Biochemistry 19901225

• [Cimetidine-induced aplastic anemia complicated with nonbacterial thrombotic endocarditis and cerebral infarction].

  [Rinsho ketsueki] The Japanese journal of clinical hematology 19901201

• Histamine blockade and cardiovascular changes following heparin administration during cardiac surgery.

  Journal of cardiothoracic anesthesia 19901201

• Hemodynamic effects of H2-receptor antagonists.

  DICP : the annals of pharmacotherapy 19901101

• Cimetidine-associated adverse reaction.

  DICP : the annals of pharmacotherapy 19900601

• Danazol induced pancreatitis and hepatitis.

  Clinical rheumatology 19900601

• [Confusion induced by the combination cimetidine-benzodiazepine; apropos of a case report].

  La Tunisie medicale 19900101

• Comparison of cimetidine and diphenhydramine in the treatment of acute urticaria.

  Annals of emergency medicine 19900101

• Cimetidine and adverse reactions: a meta-analysis of randomized clinical trials of short-term therapy.

  The American journal of medicine 19890901

• Cimetidine in the treatment of refractory anaphylaxis.

  Annals of allergy 19890901

• Effect of cimetidine and ranitidine on cardiovascular drugs.

  American heart journal 19890701

• Cimetidine-related cardiac conduction disturbances and confusion.

  Journal of clinical gastroenterology 19890201

• Famotidine and ranitidine, but not cimetidine, cause severe, disabling headache.

  The American journal of gastroenterology 19890201

• Prednisone mood disorder with associated catatonia.

  Journal of geriatric psychiatry and neurology 19890101

• Famotidine-associated mental confusion in elderly patients.

  Drug intelligence & clinical pharmacy 19881201

• Combined H1 and H2 receptor blockade attenuates the cardiovascular effects of high-dose atracurium for rapid sequence endotracheal intubation.

  Anesthesia and analgesia 19881101

• Synthesis of (aryloxy)alkylamines. 1. Novel antisecretory agents with H+K+-ATPase inhibitory activity.

  Journal of medicinal chemistry 19880901

• Colloidal bismuth subcitrate. A review of its pharmacodynamic and pharmacokinetic properties, and its therapeutic use in peptic ulcer disease.

  Drugs 19880801

• Reversible chorea due to ranitidine and cimetidine.

  Lancet (London, England) 19880716

• Are endoscopic and/or histologic findings in gastroduodenal mucosa a predictor of clinical outcome in peptic ulcer disease? A 1-year follow-up study after initial healing with either cimetidine or medium-dose antacid.

  Scandinavian journal of gastroenterology 19880301

• Aplastic anemia associated with parenteral chloramphenicol: review of 10 cases, including the second case of possible increased risk with cimetidine.

  Reviews of infectious diseases 19880101

• Prophylaxis of upper gastrointestinal tract bleeding in mechanically ventilated patients. A randomized study comparing the efficacy of sucralfate, cimetidine, and antacids.

  Archives of internal medicine 19871201

• Tagamet-induced acute dystonia.

  Annals of emergency medicine 19871001

• Meperidine-induced delirium.

  The American journal of psychiatry 19870801

• Gynaecomastia, galactorrhoea and impotence--the uncommon side effects of cimetidine therapy.

  The Journal of the Association of Physicians of India 19870601

• Bromazepam pharmacokinetics: influence of age, gender, oral contraceptives, cimetidine, and propranolol.

  Clinical pharmacology and therapeutics 19870501

• Cimetidine induces coronary artery spasm in patients with vasospastic angina.

  The Canadian journal of cardiology 19870501

• Prolonged cholestasis and cimetidine.

  Digestive diseases and sciences 19870301

• First-degree atrioventricular block induced by oral cimetidine.

  Lancet (London, England) 19870124

• Broad-complex tachycardia after intravenous cimetidine.

  Lancet (London, England) 19870110

• Systemic mastocytosis: management of an unusual case with histamine (H1 and H2) antagonists and cyclooxygenase inhibition.

  Clinical and investigative medicine. Medecine clinique et experimentale 19870101

• [Effect of bolus methylprednisolone therapy on a case of cimetidine-associated aplastic anemia].

  [Rinsho ketsueki] The Japanese journal of clinical hematology 19870101

• Bolus injection of cimetidine and hypotension in patients in the intensive care unit. Incidence and mechanisms.

  Archives of internal medicine 19870101

• Cimetidine and encephalopathy.

  Annals of internal medicine 19861201

• Cimetidine hepatitis.

  Journal of clinical gastroenterology 19861201

• [Acute renal failure associated with cimetidine].

  Harefuah 19861201

• Histamine antagonists and d-tubocurarine-induced hypotension in cardiac surgical patients.

  Clinical pharmacology and therapeutics 19861101

• Hyperpyrexia associated with intravenous cimetidine therapy. Report of a case.

  Archives of internal medicine 19860901

• Effects of cimetidine and ranitidine on local anesthetic central nervous system toxicity in mice.

  Anesthesia and analgesia 19860801

• The effects of derivatives of histamine on natural suppressor cells.

  Journal of immunology (Baltimore, Md. : 1950) 19860701

• Recurrent myalgias associated with cimetidine.

  International journal of clinical pharmacology, therapy, and toxicology 19860701

• [Three cases of hemorrhagic gastric ulcer and cimetidine-associated mental confusion].

  Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 19860701

• [Peripheral neuropathy during treatment with cimetidine].

  Revue neurologique 19860101

• [Tachycardia following a bolus of cimetidine. Drug interaction].

  Therapie 19860101

• Histamine H2 antagonists and the nervous system.

  American family physician 19851201

• Safety of cimetidine.

  British medical journal (Clinical research ed.) 19851116

• Diagnostic evaluation of 200 elderly outpatients with suspected dementia.

  Journal of gerontology 19850901

• Central nervous system toxicity associated with concurrent use of triazolam and cimetidine.

  Drug intelligence & clinical pharmacy 19850901

• Gastric cytoprotection by pirenzepine in rats: evaluating method for cytoprotective activity by antisecretory agents.

  Japanese journal of pharmacology 19850801

• [Cimetidine-induced hypoplastic anemia complicated by hepatoma: report of a case].

  [Rinsho ketsueki] The Japanese journal of clinical hematology 19850801

• Toxic 'ictal' confusion in middle age: treatment with benzodiazepines.

  Journal of neurology, neurosurgery, and psychiatry 19850501

• The interaction of cimetidine with various antihypertensive agents in the spontaneously hypertensive rat.

  The Journal of pharmacy and pharmacology 19850501

• Sinus arrest associated with cimetidine.

  Anesthesia and analgesia 19850501

• The effects of H1 and H2 histamine receptor antagonists on the development of endotoxemia in the conscious, unrestrained rat.

  Circulatory shock 19850101

• Hypersensitivity to cimetidine.

  Journal of clinical pharmacology 19850101

• Comparison of the effectiveness of ranitidine and cimetidine in inhibiting acid secretion in patients with gastric hypersecretory states.

  The American journal of medicine 19841119

• Cimetidine-induced psychosis in a 14-year-old girl.

  Canadian Medical Association journal 19841101

• Effects of histamine antagonists on noradrenaline-stimulated blood flow and oxygen consumption of brown adipose tissue in the rat.

  Pflugers Archiv : European journal of physiology 19841101

• Isolation and partial characterization of an entero-oxyntin from porcine ileum.

  Endocrinology 19841001

• Relationship of morphine-induced miosis to plasma concentration in normal subjects.

  Journal of pharmaceutical sciences 19841001

• Bronchospasm and hypotension during cardiopulmonary bypass after preoperative cimetidine and labetalol therapy.

  British journal of anaesthesia 19840801

• Ranitidine and loss of colour vision in a child.

  Lancet (London, England) 19840707

• Complete atrioventricular block and long-term cimetidine therapy.

  Archives of internal medicine 19840401

• Hemodynamic studies on cimetidine and ranitidine in anesthetized dogs.

  Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie 19840101

• Effects of cimetidine and ranitidine on halothane metabolism and hepatotoxicity in an animal model.

  Drug metabolism and disposition: the biological fate of chemicals 19840101

• Cimetidine neurotoxicity. EEG and behaviour aspects.

  European neurology 19840101

• Cimetidine-induced cutaneous vasculitis.

  The American journal of medicine 19831101

• [Cutaneous coumarin necrosis of the breast].

  Deutsche medizinische Wochenschrift (1946) 19830916

• Cimetidine-induced mania in depressed patients.

  The Journal of clinical psychiatry 19830701

• Hypotension following intravenous cimetidine.

  Anaesthesia 19830701

• Drug-induced internuclear ophthalmoplegia.

  Canadian Medical Association journal 19830415

• Cimetidine-induced impotence and breast changes in patients with gastric hypersecretory states.

  The New England journal of medicine 19830414

• Cimetidine-induced interstitial nephritis with response to prednisone therapy.

  Archives of internal medicine 19830401

• Specific binding of [3H]mepyramine to histamine H1-receptors in vascular smooth muscle membranes.

  Agents and actions 19830401

• Hypotension following cimetidine administration during cardiopulmonary bypass.

  Anaesthesia 19830301

• Ranitidine reverses cimetidine-induced mental confusion in a patient with Zollinger-Ellison syndrome.

  Archives of surgery (Chicago, Ill. : 1960) 19830201

• Cimetidine psychotoxicity without significant medical illness: case report.

  The Journal of clinical psychiatry 19830201

• Physostigmine reversal of cimetidine-induced delirium and agitation.

  Journal of clinical psychopharmacology 19830201

• Interstitial nephritis after cimetidine but not ranitidine.

  JAMA 19830121

• Immunologic studies in cimetidine-induced nephropathy and polymyositis.

  The New England journal of medicine 19830120

• The effect of antihistaminics on cataleptogenic action of analgesics and haloperidol.

  Polish journal of pharmacology and pharmacy 19830101

• Cimetidine-associated depression and loss of libido in a woman.

  The American journal of the medical sciences 19830101

• [Severe confusion following a theophylline-cimetidine combination].

  Annales francaises d'anesthesie et de reanimation 19830101

• Cimetidine: II. Adverse reactions and patterns of use.

  Annals of internal medicine 19821101

• Cimetidine, vasopressin and chronotropic incompetence.

  The Medical journal of Australia 19821030

• Extrapyramidal and cerebellar syndrome with encephalopathy associated with cimetidine.

  Postgraduate medical journal 19820801

• Ranitidine-induced bradycardia.

  Lancet (London, England) 19820717

• Cimetidine accumulation and mental confusion in cirrhosis.

  The New England journal of medicine 19820715

• Acute renal failure and rise in alkaline phosphatase activity caused by cimetidine.

  British medical journal (Clinical research ed.) 19820710

• Hypersensitivity to cimetidine.

  Annals of internal medicine 19820701

• Neurological and psychiatric side effects of cimetidine--report of 3 cases with review of the literature.

  Postgraduate medical journal 19820701

• Peripheral hypotensive and central hypertensive effects of cimetidine.

  Agents and actions 19820401

• Cimetidine and theophylline.

  Annals of internal medicine 19820301

• Cimetidine-induced acute interstitial nephritis.

  The American journal of gastroenterology 19820301

• Cimetidine-theophylline interaction: report of four patients.

  Annals of allergy 19820201

• Cimetidine-induced acute renal failure.

  Annals of internal medicine 19820201

• Age and renal clearance of cimetidine.

  Clinical pharmacology and therapeutics 19820101

• Chorea and cimetidine.

  Annals of internal medicine 19820101

• Hepatitis following cimetidine administration.

  The American journal of the medical sciences 19820101

• Respiratory depression after cimetidine reversed by physostigmine.

  Intensive care medicine 19820101

• Cardiac arrhythmias after intravenous cimetidine.

  The New England journal of medicine 19811001

• Rapid development of aplastic anemia after intravenous chloramphenicol and cimetidine therapy.

  Southern medical journal 19811001

• Interstitial nephritis induced by cimetidine.

  Canadian Medical Association journal 19811001

• Cimetidine and prolonged post-operative somnolence.

  Canadian Anaesthetists' Society journal 19810901

• Toxic optic neuropathy caused by benoxaprofen.

  British medical journal (Clinical research ed.) 19810718

• Leukoclastic vasculitis from cimetidine.

  JAMA 19810701

• Prolonged confusion after cimetidine.

  The Medical journal of Australia 19810613

• Acute interstitial nephritis and acute renal failure associated with cimetidine therapy.

  The American journal of medicine 19810601

• Potentially lethal interaction of cimetidine and morphine.

  Canadian Medical Association journal 19810601

• Depression associated with cimetidine.

  Canadian journal of psychiatry. Revue canadienne de psychiatrie 19810601

• Neurological dysfunction associated with abnormal levels of cimetidine metabolite.

  Lancet (London, England) 19810509

• Prevention of acetaminophen-induced hepatic necrosis by cimetidine in mice.

  Research communications in chemical pathology and pharmacology 19810501

• The effects of chronic oral cimetidine therapy on the cardiovascular system in man.

  British journal of clinical pharmacology 19810501

• Cimetidine toxic reactions masquerading as delirium tremens.

  JAMA 19810313

• Prolonged WBC depression after cimetidine in a patient with chronic myelogenous leukemia.

  Southern medical journal 19810301

• Differential diagnosis of cimetidine-induced delirium.

  Psychosomatics 19810301

• Cimetidine-induced hepatitis. Electron microscopic observations and clinical pattern of liver injury.

  Digestive diseases and sciences 19810301

• Chronic protracted diarrhea and jejunal atrophy in an infant. Cimetidine-associated stimulation of jejunal mucosal growth.

  Digestive diseases and sciences 19810201

• Antacid/anticholinergic, cimetidine, and placebo in treatment of active peptic ulcers.

  Scandinavian journal of gastroenterology 19810101

• Cimetidine induced postural and action tremor.

  Journal of neurology, neurosurgery, and psychiatry 19810101

• Cimetidine-induced mental status changes: case report and literature review.

  American journal of hospital pharmacy 19801201

• Cimetidine and mental confusion.

  Critical care medicine 19801201

• Cardiac arrest after intravenous injection of cimetidine.

  The Medical journal of Australia 19801129

• Myopathy associated with cimetidine?

  British medical journal 19801108

• A case report of cimetidine-induce depressive syndrome.

  The American journal of psychiatry 19801101

• Motor neuropathy associated with cimetidine.

  British medical journal 19801011

• Use of ranitidine, without mental confusion, in patients with renal failure.

  Lancet (London, England) 19801004

• Acute interstitial nephritis related to cimetidine therapy.

  Gastroenterology 19801001

• Cimetidine-induced mental confusion in patients with cirrhosis.

  Gastroenterology 19801001

• Mental confusion falsely attributed to cimetidine.

  Archives of internal medicine 19800901

• Cimetidine toxicity manifested as paranoia and hallucinations.

  The American journal of psychiatry 19800901

• Agitation, disorientation, and hallucinations in patients on cimetidine: a report of three cases and literature review.

  General hospital psychiatry 19800901

• Aplastic anemia and cimetidine.

  Archives of internal medicine 19800801

• Neurological dysfunction in two patients receiving captopril and cimetidine.

  Lancet (London, England) 19800705

• Corticosteroid treatment, serum lipids and coronary artery disease.

  Postgraduate medical journal 19800701

• Cimetidine and renal failure.

  Postgraduate medical journal 19800601

• Dose and serum concentration relationships in cimetidine-associated mental confusion.

  Gastroenterology 19800401

• Recurrence of duodenal ulcer pain after treatment with cimetidine for four and eight weeks.

  Gut 19800201

• Slow tricyclic antidepressant metabolism, polypharmacy, and cardiac arrest.

  The American journal of psychiatry 19800101

• The stimulatory effects of neurotensin and related peptides in rat stomach strips and guinea-pig atria.

  British journal of pharmacology 19800101

• Confusion associated with cimetidine.

  British medical journal 19791201

• Bone-marrow suppression associated with cimetidine.

  Annals of internal medicine 19791001

• Autoimmune haemolytic anaemia associated with cimetidine.

  Lancet (London, England) 19790915

• Reversal of cimetidine-induced stupor by physostigmine.

  JAMA 19790914

• Cimetidine hepatitis.

  Gastroenterology 19790701

• Cimetidine and giant urticaria.

  Annals of internal medicine 19790701

• Hypersensitivity to cimetidine.

  The New England journal of medicine 19790524

• Side effects of cimetidine.

  Southern medical journal 19790501

• Toxic psychosis with cimetidine.

  The American journal of psychiatry 19790501

• Male sexual dysfunction during treatment with cimetidine.

  British medical journal 19790310

• Central nervous system toxicity of cimetidine: a case of depression.

  The American journal of psychiatry 19790301

• Cimetidine and psychiatric complications.

  The British journal of psychiatry : the journal of mental science 19790301

• Cimetidine: does neurotoxicity occur? Report of three cases.

  Journal of the Royal Society of Medicine 19790301

• Physostigmine reversal of cimetidine--induced mental confusion.

  JAMA 19790223

• Pharmacokinetic and clinical studies in patients with cimetidine-associated mental confusion.

  Lancet (London, England) 19790127

• A comparison of the cardiovascular effects of centrally administered clonidine and adrenaline in the anaesthetized rat.

  The Journal of pharmacy and pharmacology 19790101

• [The therapeutic importance of cimetidine (Tagamet) (author's transl)].

  MMW, Munchener medizinische Wochenschrift 19781103

• Cimetidine-induced coma in cirrhosis of the liver.

  JAMA 19780915

• Cimetidine and visual hallucinations.

  JAMA 19780721

• Cimetidine-induced coma.

  Lancet (London, England) 19780701

• Cimetidine cholestatic jaundice in children.

  The Journal of surgical research 19780501

• Cimetidine and bradycardia.

  Lancet (London, England) 19780415

• Hypotension after intravenous cimetidine.

  Lancet (London, England) 19780415

• Fever, abdominal pain, and leucopenia during treatment with cimetidine.

  British medical journal 19780325

• Clonidine-induced hypotension: further evidence for a central interaction with histamine H2 receptor antagonists in the rat.

  Neuropharmacology 19780101

• Bradycardia after cimetidine.

  Lancet (London, England) 19771210

• [Treatment of peptic ulcer in the Zollinger-Ellison syndrome with histamine H2-receptor antagonists (author's transl)].

  Deutsche medizinische Wochenschrift (1946) 19771125

• Cimetidine and mental-confusion.

  Lancet (London, England) 19771001

• Cimetidine and renal failure.

  Lancet (London, England) 19771001