52286-58-5 | Ginsenoside rf

Packsize	Purity	Availability	Price	Discounted Price
1mg	95%	in stock	$57.00	$40.00
5mg	95%	in stock	$249.00	$174.00
10mg	95%	in stock	$413.00	$289.00

Description

• Catalog Number: AG18895
• Chemical Name: Ginsenoside rf
• CAS Number: 52286-58-5
• Molecular Formula: C42H72O14
• Molecular Weight: 801.0127
• MDL Number: MFCD00210509
• SMILES: OC[C@H]1O[C@@H](O[C@H]2C[C@]3(C)[C@@H]([C@@]4([C@@H]2C(C)(C)[C@@H](O)CC4)C)C[C@H]([C@H]2[C@@]3(C)CC[C@@H]2[C@](CCC=C(C)C)(O)C)O)[C@@H]([C@H]([C@@H]1O)O)O[C@@H]1O[C@H](CO)[C@H]([C@@H]([C@H]1O)O)O

Computed Properties

• Complexity: 1410
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 21
• Heavy Atom Count: 56
• Hydrogen Bond Acceptor Count: 14
• Hydrogen Bond Donor Count: 10
• Rotatable Bond Count: 10
• XLogP3: 2.7

Literature

• Bioactive constituents from the roots of Panax japonicus var. major and development of a LC-MS/MS method for distinguishing between natural and artifactual compounds.

  Journal of natural products 20110425

• Induction of CYP3A4 and MDR1 gene expression by baicalin, baicalein, chlorogenic acid, and ginsenoside Rf through constitutive androstane receptor- and pregnane X receptor-mediated pathways.

  European journal of pharmacology 20100825

• Rapid qualitative and quantitative analyses of Asian ginseng in adulterated American ginseng preparations by UPLC/Q-TOF-MS.

  Journal of pharmaceutical and biomedical analysis 20100501

• Microbial conversion of rare ginsenoside Rf to 20(S)-protopanaxatriol by Aspergillus niger.

  Bioscience, biotechnology, and biochemistry 20100101

• Biotransformation of ginsenoside Rf to Rh1 by recombinant beta-glucosidase.

  Molecules (Basel, Switzerland) 20090608

• [A quantitative method using one marker for simultaneous assay of ginsenosides in Panax ginseng and P. notoginseng].

  Yao xue xue bao = Acta pharmaceutica Sinica 20081201

• Neuroprotective effects of ginseng saponins against L-type Ca2+ channel-mediated cell death in rat cortical neurons.

  Biochemical and biophysical research communications 20080118

• Retention behavior of ginsenosides on a poly(vinyl alcohol)-bonded stationary phase in hydrophilic interaction chromatography.

  Analytical and bioanalytical chemistry 20071101

• Inhibitory effects of Korean red ginseng and its genuine constituents ginsenosides Rg3, Rf, and Rh2 in mouse passive cutaneous anaphylaxis reaction and contact dermatitis models.

  Biological & pharmaceutical bulletin 20060901

• Ginsenoside Rf, a component of ginseng, regulates lipoprotein metabolism through peroxisome proliferator-activated receptor alpha.

  Biochemical and biophysical research communications 20060106

• Modulating effect of ginseng saponins on heterologously expressed HERG currents in Xenopus oocytes.

  Acta pharmacologica Sinica 20050501

• [Study on the chemical constituents of the roots of commercial ginseng].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20030601

• Ginsenoside Rf potentiates U-50,488H-induced analgesia and inhibits tolerance to its analgesia in mice.

  Life sciences 20030103

• Functional expression of a novel ginsenoside Rf binding protein from rat brain mRNA in Xenopus laevis oocytes.

  Molecular pharmacology 20020401

• The antimetastatic and immunomodulating activities of ginseng minor glycosides.

  Doklady. Biochemistry and biophysics 20010101