524684-52-4 | Prinaberel

Packsize	Purity	Availability	Price	Discounted Price
1mg	95%	in stock	$47.00	$33.00
5mg	95%	in stock	$82.00	$57.00
10mg	95%	in stock	$114.00	$80.00
50mg	95%	in stock	$365.00	$256.00
100mg	95%	in stock	$522.00	$365.00

Description

• Catalog Number: AG20911
• Chemical Name: Prinaberel
• CAS Number: 524684-52-4
• Molecular Formula: C15H10FNO3
• Molecular Weight: 271.2432032
• MDL Number: MFCD09954141
• SMILES: C=Cc1cc(O)cc2c1oc(n2)c1ccc(c(c1)F)O

Computed Properties

• Complexity: 367
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 20
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 2
• XLogP3: 3.6

Literature

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  Arthritis care & research 20101101

• Estrogen receptor beta-selective agonists stimulate calcium oscillations in human and mouse embryonic stem cell-derived neurons.

  PloS one 20100101

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  The Journal of pharmacology and experimental therapeutics 20080701

• Selective estrogen receptor-beta agonists repress transcription of proinflammatory genes.

  Journal of immunology (Baltimore, Md. : 1950) 20080101

• An estrogen receptor-beta agonist is active in models of inflammatory and chemical-induced pain.

  European journal of pharmacology 20061228

• Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.

  Journal of molecular graphics & modelling 20061101

• Design and synthesis of aryl diphenolic azoles as potent and selective estrogen receptor-beta ligands.

  Journal of medicinal chemistry 20041007

• Evaluation of an estrogen receptor-beta agonist in animal models of human disease.

  Endocrinology 20031001