52670-38-9 | 2-Ethynylaniline

Packsize	Purity	Availability	Price	Discounted Price
250mg	98%	in stock	$8.00	$6.00
1g	98%	in stock	$14.00	$10.00
5g	98%	in stock	$44.00	$31.00
10g	98%	in stock	$78.00	$55.00
25g	98%	in stock	$193.00	$136.00

Description

• Catalog Number: AG26588
• Chemical Name: 2-Ethynylaniline
• CAS Number: 52670-38-9
• Molecular Formula: C8H7N
• Molecular Weight: 117.1479
• MDL Number: MFCD00168862
• SMILES: C#Cc1ccccc1N

Computed Properties

• Complexity: 131
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 9
• Hydrogen Bond Acceptor Count: 1
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 1
• XLogP3: 1.5

Literature

• Copper-catalyzed [5+1] annulation of 2-ethynylanilines with an N,O-acetal leading to construction of quinoline derivatives.

  Organic letters 20120203

• Remodelling of the natural product fumagillol employing a reaction discovery approach.

  Nature chemistry 20111201

• New tetradentate N,N,N,N-chelating α-diimine ligands and their corresponding zinc and nickel complexes: synthesis, characterisation and testing as olefin polymerisation catalysts.

  Dalton transactions (Cambridge, England : 2003) 20110407

• A facile route to polysubstituted indoles via three-component reaction of 2-ethynylaniline, sulfonyl azide, and nitroolefin.

  Organic letters 20110304

• The mechanism of N-vinylindole formation via tandem imine formation and cycloisomerisation of o-ethynylanilines.

  Dalton transactions (Cambridge, England : 2003) 20091214

• Efficient synthesis of 5,6-dihydroxyindole dimers, key eumelanin building blocks, by a unified o-ethynylaniline-based strategy for the construction of 2-linked biindolyl scaffolds.

  The Journal of organic chemistry 20090918

• Construction of nitrogen heterocycles bearing an aminomethyl group by copper-catalyzed domino three-component coupling-cyclization.

  The Journal of organic chemistry 20090918

• InBr3-promoted divergent approach to polysubstituted indoles and quinolines from 2-ethynylanilines: switch from an intramolecular cyclization to an intermolecular dimerization by a type of terminal substituent group.

  The Journal of organic chemistry 20080606

• Fast CE for combinatorial catalysis.

  Electrophoresis 20080101

• Design and synthesis of beta-methoxyacrylate analogues via click chemistry and biological evaluations.

  Bioorganic & medicinal chemistry letters 20070401

• Direct synthesis of polysubstituted quinoline derivatives by InBr3-promoted dimerization of 2-ethynylaniline derivatives.

  The Journal of organic chemistry 20060428

• Synthesis of 4H-3,1-benzoxazines, quinazolin-2-ones, and quinoline-4-ones by palladium-catalyzed oxidative carbonylation of 2-ethynylaniline derivatives.

  The Journal of organic chemistry 20040402

• Development of an efficient procedure for indole ring synthesis from 2-ethynylaniline derivatives catalyzed by CuII salts and its application to natural product synthesis.

  The Journal of organic chemistry 20040220