53251-94-8 | Pinaverium bromide

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$11.00	$8.00
5g	98%	in stock	$35.00	$25.00
25g	98%	in stock	$118.00	$83.00
100g	98%	in stock	$388.00	$272.00

Description

• Catalog Number: AI51928
• Chemical Name: Pinaverium bromide
• CAS Number: 53251-94-8
• Molecular Formula: C26H41Br2NO4
• Molecular Weight: 591.416
• MDL Number: MFCD01713435
• SMILES: COc1cc(C[N+]2(CCOCCC3CCC4CC3C4(C)C)CCOCC2)c(cc1OC)Br.[Br-]

Computed Properties

• Complexity: 596
• Covalently-Bonded Unit Count: 2
• Heavy Atom Count: 33
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 10
• Undefined Atom Stereocenter Count: 3

Literature

• Pinaverium Reduces Symptoms of Irritable Bowel Syndrome in a Multicenter, Randomized, Controlled Trial.

  Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20150701

• [Comparative observation on therapeutic effects between acupuncture and western medication for diarrhea-predominant irritable bowel syndrome].

  Zhongguo zhen jiu = Chinese acupuncture & moxibustion 20120801

• Exfoliative erythrodermia induced by pantoprazole.

  Allergologia et immunopathologia 20120101

• A sensitive and specific liquid chromatography/tandem mass spectrometry method for determination of pinaverium bromide in human plasma: application to a pharmacokinetic study in healthy volunteers.

  Biomedical chromatography : BMC 20111201

• Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

  PLoS computational biology 20111201

• The stapled hemorrhoidopexy syndrome: a new clinical entity?

  Techniques in coloproctology 20111001

• [Effect of jianpi tiaogan wenshen recipe in treating diarrhea-predominant irritable bowel syndrome].

  Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20100101

• Effect of four medications associated with gastrointestinal motility on Oddi sphincter in the rabbit.

  Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 20090101

• [Pinaverium bromide-induced esophageal ulcerations].

  Therapie 20080101

• [Drug treatment of irritable bowel syndrome: an unmet need].

  Gastroenterologia y hepatologia 20070301

• [New approaches to diagnosing and treating hyperkinetic biliary dyskinesia associated with chronic acalculous cholecystitis].

  Klinicheskaia meditsina 20040101

• Quaternary ammonium derivatives as spasmolytics for irritable bowel syndrome.

  Current pharmaceutical design 20040101

• [Randomized controlled clinical study on effect of Chinese compound changjitai in treating diarrheic irritable bowel syndrome].

  Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20031101

• Effect of pinaverium bromide on stress-induced colonic smooth muscle contractility disorder in rats.

  World journal of gastroenterology 20030315

• [Effects of dicetel on gastrointestinal motility and vegetative dysfunction in patients with duodenal ulcer].

  Klinicheskaia meditsina 20030101

• Contraction of human colonic circular smooth muscle cells is inhibited by the calcium channel blocker pinaverium bromide.

  Cell calcium 20010601

• [Current approaches to the diagnosis and treatment of irritable bowel syndrome].

  Likars'ka sprava 20010101

• Irritable bowel syndrome treatment using pinaverium bromide as a calcium channel blocker. A randomized double-blind placebo-controlled trial.

  Acta gastroenterologica Latinoamericana 19950101

• Effect of pinaverium and other calcium channel blockers on contraction of isolated gastric antral smooth muscle cells caused by gastrointestinal hormones.

  Life sciences 19940101

• Interaction of pinaverium (a quaternary ammonium compound) with 1,4-dihydropyridine binding sites in rat ileum smooth muscle.

  British journal of pharmacology 19920201

• Action of pinaverium bromide, a calcium-antagonist, on gastrointestinal motility disorders.

  General pharmacology 19900101

• Effects of pinaverium bromide and verapamil on the motility of the rat isolated colon.

  British journal of pharmacology 19850901

• Inhibitory effect of pinaverium bromide on gastrointestinal contractile activity in conscious dogs.

  Arzneimittel-Forschung 19810101