53671-71-9 | Ici 89406

Packsize	Purity	Availability	Price	Discounted Price
100mg	95%	in stock	$258.00	$180.00
250mg	95%	in stock	$572.00	$400.00

Description

• Catalog Number: AB74736
• Chemical Name: Ici 89406
• CAS Number: 53671-71-9
• Molecular Formula: C19H22N4O3
• Molecular Weight: 354.4030
• MDL Number: MFCD00673934
• SMILES: N#Cc1ccccc1OCC(CNCCNC(=O)Nc1ccccc1)O

Computed Properties

• Complexity: 459
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 26
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 4
• Rotatable Bond Count: 9
• Undefined Atom Stereocenter Count: 1
• XLogP3: 1.1

Upstream Synthesis Route

The ICI 89406 is a versatile compound widely utilized in chemical synthesis for its remarkable ability to function as a powerful catalyst in various reactions. Known for its exceptional reactivity and selectivity, this compound plays a crucial role in promoting key transformations in organic synthesis. With its unique properties, ICI 89406 enables chemists to efficiently perform a variety of challenging reactions, leading to the creation of complex molecules with high precision. From facilitating intricate bond formations to driving important chemical processes, the application of ICI 89406 in chemical synthesis is essential for advancing research and development in the field of organic chemistry.

Literature

• Preclinical evaluation of an 18F-labelled beta1-adrenoceptor selective radioligand based on ICI 89,406.

  Nuclear medicine and biology 20100501

• Are [O-methyl-11C]derivatives of ICI 89,406 beta1-adrenoceptor selective radioligands suitable for PET?

  European journal of nuclear medicine and molecular imaging 20080101

• Different changes of plasma membrane beta-adrenoceptors in rat heart after chronic administration of propranolol, atenolol and bevantolol.

  Life sciences 20070712

• Design of new beta1-selective adrenoceptor ligands as potential radioligands for in vivo imaging.

  Bioorganic & medicinal chemistry 20030805

• [High non-specific binding of the beta(1) -selective radioligand 2-(125)I-ICI-H].

  Nuklearmedizin. Nuclear medicine 20030801

• Evaluation of beta-adrenergic receptor subtypes in the human prostate cancer cell line-LNCaP.

  Biochemical pharmacology 20030501

• Molecular pharmacology of the beta-adrenergic receptor on THP-1 cells.

  International journal of immunopharmacology 19930201