540-37-4 | 4-Iodoaniline

Packsize	Purity	Availability	Price	Discounted Price
5g	97%	in stock	$8.00	$5.00
10g	97%	in stock	$9.00	$6.00
25g	97%	in stock	$13.00	$9.00
500g	97%	in stock	$249.00	$175.00

Description

• Catalog Number: AB45053
• Chemical Name: 4-Iodoaniline
• CAS Number: 540-37-4
• Molecular Formula: C6H6IN
• Molecular Weight: 219.023
• MDL Number: MFCD00007848
• SMILES: Nc1ccc(cc1)I
• NSC Number: 9246

Computed Properties

• Complexity: 66.9
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 8
• Hydrogen Bond Acceptor Count: 1
• Hydrogen Bond Donor Count: 1
• XLogP3: 2.3

Upstream Synthesis Route

4-Iodoaniline is a versatile compound commonly utilized in chemical synthesis as a key building block. Due to its unique structure and reactivity, 4-Iodoaniline finds application in a wide range of organic transformations, particularly in the formation of pharmaceuticals, agrochemicals, and advanced materials. When used in reactions such as nucleophilic aromatic substitution, cross-coupling reactions, and transition metal-catalyzed transformations, 4-Iodoaniline serves as a valuable precursor for the synthesis of various biologically active molecules and functionalized intermediates. Its ability to undergo selective functionalization at the iodine position enables chemists to introduce diverse functional groups, facilitating the creation of complex molecular structures with tailored properties. Additionally, the presence of both an amino and an iodine group in 4-Iodoaniline offers opportunities for further derivatization, enabling the synthesis of novel compounds with enhanced biological or physical characteristics. Whether employed as a reagent for carbon-carbon bond formation or as a starting material for heterocycle synthesis, 4-Iodoaniline remains an indispensable tool in the toolbox of synthetic chemists, driving innovation and discovery in the field of organic chemistry.

Literature

• Differentiation of complex lipid isomers by radical-directed dissociation mass spectrometry.

  Analytical chemistry 20120904

• In situ synthesis of thermochemically reduced graphene oxide conducting nanocomposites.

  Nano letters 20120411

• Consequence of one-electron oxidation and one-electron reduction for aniline.

  Journal of molecular modeling 20111201

• 4-Iodo-anilinium perchlorate 18-crown-6 clathrate.

  Acta crystallographica. Section E, Structure reports online 20110301

• (E)-2-[(4-Iodo-phen-yl)imino-meth-yl]-6-methyl-phenol.

  Acta crystallographica. Section E, Structure reports online 20100701

• 4-Iodo-anilinium nitrate.

  Acta crystallographica. Section E, Structure reports online 20100601

• 4-Iodo-anilinium perchlorate.

  Acta crystallographica. Section E, Structure reports online 20100401

• 2,4-Diiodo-aniline.

  Acta crystallographica. Section E, Structure reports online 20090901

• 2-Chloro-4-iodo-aniline.

  Acta crystallographica. Section E, Structure reports online 20081201

• 2-Iodo-N-(2-nitro-phenyl-sulfan-yl)aniline.

  Acta crystallographica. Section E, Structure reports online 20080801

• Mouse N-acetyltransferase type 2, the homologue of human N-acetyltransferase type 1.

  Biochemical pharmacology 20080401

• Sorption and transport of iodine species in sediments from the Savannah River and Hanford Sites.

  Journal of contaminant hydrology 20050701

• In situ electrochemical ESR and voltammetric studies on the anodic oxidation of para-haloanilines in acetonitrile.

  The journal of physical chemistry. B 20050630

• Supramolecular structures of four isomorphous anilinium 2-carboxy-4-nitrobenzoate salts: 4-X-C6H4NH3+.C8H4NO6- (X = H, Cl, Br and I).

  Acta crystallographica. Section C, Crystal structure communications 20050501

• Eukaryotic arylamine N-acetyltransferase. Investigation of substrate specificity by high-throughput screening.

  Biochemical pharmacology 20050115

• 4-iodoanilinium 3-nitrophthalate(1-): tripartite sheets built from O-H...O and N-H...O hydrogen bonds.

  Acta crystallographica. Section C, Crystal structure communications 20030901

• Potential of neurotoxicity after a single oral dose of 4-bromo-, 4-chloro-, 4-fluoro- or 4-iodoaniline in rats.

  Journal of applied toxicology : JAT 20030101