5407-87-4 | 2-Amino-4,6-dimethylpyridine

Packsize	Purity	Availability	Price	Discounted Price
250mg	95%	in stock	$15.00	$10.00
1g	95%	in stock	$16.00	$11.00
5g	95%	in stock	$31.00	$22.00
10g	95%	in stock	$56.00	$39.00
25g	95%	in stock	$116.00	$81.00
100g	95%	in stock	$431.00	$302.00

Description

• Catalog Number: AB61033
• Chemical Name: 2-Amino-4,6-dimethylpyridine
• CAS Number: 5407-87-4
• Molecular Formula: C7H10N2
• Molecular Weight: 122.1677
• MDL Number: MFCD00006322
• SMILES: Cc1cc(C)nc(c1)N
• NSC Number: 10731

Computed Properties

• Complexity: 92.9
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 9
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 1
• XLogP3: 1.3

Upstream Synthesis Route

2-Amino-4,6-dimethylpyridine is a versatile chemical compound frequently employed in organic synthesis. This compound serves as a valuable building block in the creation of various pharmaceuticals, agrochemicals, and specialty chemicals due to its unique properties and reactivity. In chemical synthesis, 2-Amino-4,6-dimethylpyridine is commonly used as a nucleophilic ligand to facilitate metal-catalyzed cross-coupling reactions, such as Suzuki-Miyaura and Heck reactions, leading to the formation of complex organic compounds. This compound also acts as a chelating agent in coordination chemistry, enabling the formation of stable metal complexes that are crucial in catalyzing diverse chemical transformations. Additionally, 2-Amino-4,6-dimethylpyridine plays a pivotal role in the synthesis of heterocyclic compounds, which are prevalent in medicinal chemistry and material science. Its ability to participate in various functional group transformations and its compatibility with a wide range of reaction conditions make 2-Amino-4,6-dimethylpyridine a valuable tool for chemists seeking to design and develop novel molecules with specific properties and applications.

Literature

• 2-Amino-4,6-dimethyl-pyridinium chloride dihydrate.

  Acta crystallographica. Section E, Structure reports online 20111001

• Novel nanomolar imidazo[4,5-b]pyridines as selective nitric oxide synthase (iNOS) inhibitors: SAR and structural insights.

  Bioorganic & medicinal chemistry letters 20110715

• 2-Amino-4,6-dimethyl-pyridinium benzoate.

  Acta crystallographica. Section E, Structure reports online 20101001

• L337H mutant of rat neuronal nitric oxide synthase resembles human neuronal nitric oxide synthase toward inhibitors.

  Journal of medicinal chemistry 20090723

• Synthesis and evaluation of pyrido[1,2-a]pyrimidines as inhibitors of nitric oxide synthases.

  European journal of medicinal chemistry 20090701

• 2-aminopyridines as highly selective inducible nitric oxide synthase inhibitors. Differential binding modes dependent on nitrogen substitution.

  Journal of medicinal chemistry 20040603

• In vitro and in vivo antileishmanial activity of 2-amino-4,6-dimethylpyridine derivatives against Leishmania mexicana.

  Parasite (Paris, France) 20021201

• New N-pyridinyl(methyl)-indole-2- and 3-(alkyl)carboxamides and derivatives acting as systemic and topical inflammation inhibitors.

  Journal of enzyme inhibition and medicinal chemistry 20021201