5466-88-6 | 2H-1,4-Benzoxazin-3(4H)-one

Packsize	Purity	Availability	Price	Discounted Price
5g	95%	in stock	$13.00	$9.00
25g	95%	in stock	$31.00	$22.00
100g	98%	in stock	$119.00	$84.00

Description

• Catalog Number: AB62261
• Chemical Name: 2H-1,4-Benzoxazin-3(4H)-one
• CAS Number: 5466-88-6
• Molecular Formula: C8H7NO2
• Molecular Weight: 149.1467
• MDL Number: MFCD00158536
• SMILES: O=C1COc2c(N1)cccc2
• NSC Number: 26354

Computed Properties

• Complexity: 170
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 1
• XLogP3: 0.9

Literature

• In silico characterization of three two-component systems of Ehrlichia canis and evaluation of a natural plant-derived inhibitor.

  Genetics and molecular research : GMR 20121004

• Synthesis of 2H-benzo[b][1,4]oxazin-3(4H)-one derivatives as platelet aggregation inhibitors.

  Bioorganic & medicinal chemistry letters 20120101

• Synthesis and pharmacological evaluations of novel 2H-benzo[b][1,4]oxazin-3(4H)-one derivatives as a new class of anti-cancer agents.

  European journal of medicinal chemistry 20111001

• Structure-activity relationship of benzoxazinones and related compounds with respect to the growth inhibition and alpha-amylase activity in cress seedlings.

  Journal of plant physiology 20101015

• Fluconazole analogues containing 2H-1,4-benzothiazin-3(4H)-one or 2H-1,4-benzoxazin-3(4H)-one moieties, a novel class of anti-Candida agents.

  Bioorganic & medicinal chemistry letters 20100115

• Aromatic-ring-functionalised benzoxazinones in the system Oryza sativa-Echinochloa crus-galli as biorational herbicide models.

  Pest management science 20091001

• Rediscovering the bioactivity and ecological role of 1,4-benzoxazinones.

  Natural product reports 20090401

• Synthesis of novel 1,4-benzoxazin-3-one derivatives as inhibitors against tyrosine kinases.

  Bioorganic & medicinal chemistry 20090115

• Synthesis of novel 7-benzylamino-2H-1,4-benzoxazin-3(4H)-ones as anticonvulsant agents.

  European journal of medicinal chemistry 20080601

• Novel potent and selective thrombin inhibitors based on a central 1,4-benzoxazin-3(4H)-one scaffold.

  Journal of medicinal chemistry 20080508

• Study on bioactive compounds from Streptomyces sp. ANU 6277.

  Polish journal of microbiology 20080101

• Bad housekeeping: why do aphids leave their exuviae inside the colony?

  BMC evolutionary biology 20080101

• Benzofused tricycles based on 2-quinoxalinol.

  Journal of combinatorial chemistry 20070101

• Isolation and synthesis of allelochemicals from gramineae: benzoxazinones and related compounds.

  Journal of agricultural and food chemistry 20060222

• Toward a novel class of antithrombotic compounds with dual function. Discovery of 1,4-benzoxazin-3(4H)-one derivatives possessing thrombin inhibitory and fibrinogen receptor antagonistic activities.

  Journal of medicinal chemistry 20050505

• Design and synthesis of novel platelet fibrinogen receptor antagonists with 2H-1,4-benzoxazine-3(4H)-one scaffold. A systematic study.

  European journal of medicinal chemistry 20050101

• Chemical basis for the antifeedant activity of natural hydroxamic acids and related compounds.

  Journal of agricultural and food chemistry 20040505

• Utilisation of electrospray time-of-flight mass spectrometry for solving complex fragmentation patterns: application to benzoxazinone derivatives.

  Journal of mass spectrometry : JMS 20031001

• Antitumor agents. Part 218: Cappamensin A, a new In vitro anticancer principle, from Capparis sikkimensis.

  Bioorganic & medicinal chemistry letters 20030707

• Development of a liquid chromatography-electrospray-tandem mass spectrometry method for the quantitative determination of benzoxazinone derivatives in plants.

  Analytical chemistry 20030701

• Effects of 1,4-benzoxazin-3-one derivatives from maize on survival and fecundity of Metopolophium dirhodum (Walker) on artificial diet.

  Journal of chemical ecology 20010201