554-01-8 | 5-Methylcytosine

Packsize	Purity	Availability	Price	Discounted Price
1g	99%	in stock	$14.00	$10.00
5g	99%	in stock	$17.00	$12.00
10g	99%	in stock	$21.00	$15.00
25g	99%	in stock	$47.00	$33.00
100g	99%	in stock	$187.00	$131.00

Description

• Catalog Number: AI52415
• Chemical Name: 5-Methylcytosine
• CAS Number: 554-01-8
• Molecular Formula: C5H7N3O
• Molecular Weight: 125.1286
• MDL Number: MFCD12755169
• SMILES: Cc1c[nH]c(=O)nc1N
• NSC Number: 137776

Computed Properties

• Complexity: 204
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 9
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 2
• XLogP3: -0.8

Literature

• A cross-omics approach to investigate temporal gene expression regulation by 5-hydroxymethylcytosine via TBH-derived oxidative stress showed involvement of different regulatory kinases.

  Toxicology in vitro : an international journal published in association with BIBRA 20180401

• Selective inhibition of CTCF binding by iAs directs TET-mediated reprogramming of 5-hydroxymethylation patterns in iAs-transformed cells.

  Toxicology and applied pharmacology 20180101

• Altered mitochondrial epigenetics associated with subchronic doxorubicin cardiotoxicity.

  Toxicology 20170901

• DNA demethylation mediated by down-regulated TETs in the testes of rare minnow Gobiocypris rarus under bisphenol A exposure.

  Chemosphere 20170301

• Genome-wide alteration in DNA hydroxymethylation in the sperm from bisphenol A-exposed men.

  PloS one 20170101

• Epigenetic modulations in early endothelial cells and DNA hypermethylation in human skin after sulfur mustard exposure.

  Toxicology letters 20160226

• Evaluation of 5-methylcytosine and 5-hydroxymethylcytosine as potential biomarkers for characterisation of chemical allergens.

  Toxicology 20160118

• The effect of a methyl-deficient diet on the global DNA methylation and the DNA methylation regulatory pathways.

  Journal of applied toxicology : JAT 20151201

• Prenatal arsenic exposure and the epigenome: identifying sites of 5-methylcytosine alterations that predict functional changes in gene expression in newborn cord blood and subsequent birth outcomes.

  Toxicological sciences : an official journal of the Society of Toxicology 20150101

• Elevated 5-hydroxymethylcytosine in the Engrailed-2 (EN-2) promoter is associated with increased gene expression and decreased MeCP2 binding in autism cerebellum.

  Translational psychiatry 20141001

• Epigenetic regulation of a brain-specific glycosyltransferase N-acetylglucosaminyltransferase-IX (GnT-IX) by specific chromatin modifiers.

  The Journal of biological chemistry 20140418

• Cadmium exposure and the epigenome: Exposure-associated patterns of DNA methylation in leukocytes from mother-baby pairs.

  Epigenetics 20140201

• Redox-active quinones induces genome-wide DNA methylation changes by an iron-mediated and Tet-dependent mechanism.

  Nucleic acids research 20140201

• Prenatal exposure to BPA alters the epigenome of the rat mammary gland and increases the propensity to neoplastic development.

  PloS one 20140101

• Cerebellar oxidative DNA damage and altered DNA methylation in the BTBR T+tf/J mouse model of autism and similarities with human post mortem cerebellum.

  PloS one 20140101

• Behavioral and neurobiological effects of prenatal stress exposure in male and female APPswe/PS1dE9 mice.

  Neurobiology of aging 20130101

• DNA hypomethylation and hemimethylation in cancer.

  Advances in experimental medicine and biology 20130101

• Ten eleven translocation enzymes and 5-hydroxymethylation in mammalian development and cancer.

  Advances in experimental medicine and biology 20130101

• Methods for cancer epigenome analysis.

  Advances in experimental medicine and biology 20130101

• Promoter methylation and age-related downregulation of Klotho in rhesus monkey.

  Age (Dordrecht, Netherlands) 20121201

• Effect of aging on 5-hydroxymethylcytosine in brain mitochondria.

  Neurobiology of aging 20121201

• Zebrafish (Danio rerio) as a model for investigating dietary toxic effects of deoxynivalenol contamination in aquaculture feeds.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20121201

• 5-Hydroxymethylcytosine--the elusive epigenetic mark in mammalian DNA.

  Chemical Society reviews 20121107

• Palladium electrodes for molecular tunnel junctions.

  Nanotechnology 20121026

• Sequencing the sixth base (5-hydroxymethylcytosine): selective DNA oxidation enables base-pair resolution.

  Angewandte Chemie (International ed. in English) 20121022

• Genome-wide and caste-specific DNA methylomes of the ants Camponotus floridanus and Harpegnathos saltator.

  Current biology : CB 20121009

• Methylcytosine and normal cytosine deamination by the foreign DNA restriction enzyme APOBEC3A.

  The Journal of biological chemistry 20121005

• Low values of 5-hydroxymethylcytosine (5hmC), the 'sixth base,' are associated with anaplasia in human brain tumors.

  International journal of cancer 20121001

• Dynamics of DNA methylation in aging and Alzheimer's disease.

  DNA and cell biology 20121001

• TET2 is essential for survival and hematopoietic stem cell homeostasis.

  Leukemia 20121001

• Increased cleavage rate of human nuclear transfer embryos after 5-aza-2'-deoxycytidine treatment.

  Reproductive biomedicine online 20121001

• 5-hmC in the brain is abundant in synaptic genes and shows differences at the exon-intron boundary.

  Nature structural & molecular biology 20121001

• The anti-CMS technique for genome-wide mapping of 5-hydroxymethylcytosine.

  Nature protocols 20121001

• The GLIB technique for genome-wide mapping of 5-hydroxymethylcytosine.

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• The role of DNA methylation in aging, rejuvenation, and age-related disease.

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• Reconstitution of the very short patch repair pathway from Escherichia coli.

  The Journal of biological chemistry 20120921

• CpG site-specific alteration of hydroxymethylcytosine to methylcytosine beyond DNA replication.

  Biochemical and biophysical research communications 20120914

• Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma.

  Cell 20120914

• Out-of-plane low-frequency vibrations and nonradiative decay in the 1ππ* state of jet-cooled 5-methylcytosine.

  The journal of physical chemistry. B 20120913

• Effect of valproic acid on mitochondrial epigenetics.

  European journal of pharmacology 20120905

• DNA methylation analysis triggered by bulge specific immuno-recognition.

  Analytical chemistry 20120904

• Differential effect of three base modifications on DNA thermostability revealed by high resolution melting.

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• Aberrant epigenetic modifications in peripheral blood mononuclear cells from patients with pemphigus vulgaris.

  The British journal of dermatology 20120901

• Histone H1 affects gene imprinting and DNA methylation in Arabidopsis.

  The Plant journal : for cell and molecular biology 20120901

• Theoretical study of the interaction between 5-methylcytosine and acrylamide.

  Journal of molecular modeling 20120901

• AID/APOBEC deaminases disfavor modified cytosines implicated in DNA demethylation.

  Nature chemical biology 20120901

• IDH1 mutations inhibit multiple α-ketoglutarate-dependent dioxygenase activities in astroglioma.

  Journal of neuro-oncology 20120901

• Diurnal expression of Dnmt3b mRNA in mouse liver is regulated by feeding and hepatic clockwork.

  Epigenetics 20120901

• New cytosine derivatives as inhibitors of DNA methylation.

  European journal of medicinal chemistry 20120901

• Ligand-incorporation site in 5-methylcytosine-detection probe modulating the site of osmium complexation with the target DNA.

  Chemistry & biodiversity 20120901

• Early-stage epigenetic modification during somatic cell reprogramming by Parp1 and Tet2.

  Nature 20120830

• Widespread existence of cytosine methylation in yeast DNA measured by gas chromatography/mass spectrometry.

  Analytical chemistry 20120821

• Grape seed proanthocyanidins reactivate silenced tumor suppressor genes in human skin cancer cells by targeting epigenetic regulators.

  Toxicology and applied pharmacology 20120815

• Binding of the J-binding protein to DNA containing glucosylated hmU (base J) or 5-hmC: evidence for a rapid conformational change upon DNA binding.

  Journal of the American Chemical Society 20120815

• Effect of donor cell type on nuclear remodelling in rabbit somatic cell nuclear transfer embryos.

  Reproduction in domestic animals = Zuchthygiene 20120801

• A null mutation of ROS1a for DNA demethylation in rice is not transmittable to progeny.

  The Plant journal : for cell and molecular biology 20120801

• Autopolyploidy differentially influences body size in plants, but facilitates enhanced accumulation of secondary metabolites, causing increased cytosine methylation.

  The Plant journal : for cell and molecular biology 20120801

• Simultaneous determination of global DNA methylation and hydroxymethylation levels by hydrophilic interaction liquid chromatography-tandem mass spectrometry.

  Journal of biomolecular screening 20120801

• Nuclear exclusion of TET1 is associated with loss of 5-hydroxymethylcytosine in IDH1 wild-type gliomas.

  The American journal of pathology 20120801

• Air pollution and DNA methylation: interaction by psychological factors in the VA Normative Aging Study.

  American journal of epidemiology 20120801

• 5-formylcytosine and 5-carboxylcytosine reduce the rate and substrate specificity of RNA polymerase II transcription.

  Nature structural & molecular biology 20120801

• AIDing the immune system-DIAbolic in cancer.

  Seminars in immunology 20120801

• Association of a multi-synthetase complex with translating ribosomes in the archaeon Thermococcus kodakarensis.

  FEBS letters 20120730

• Crystal structure of human methyl-binding domain IV glycosylase bound to abasic DNA.

  Journal of molecular biology 20120713

• Cancer genetics and epigenetics: two sides of the same coin?

  Cancer cell 20120710

• Targeted disruption of an orthologue of DOMAINS REARRANGED METHYLASE 2, OsDRM2, impairs the growth of rice plants by abnormal DNA methylation.

  The Plant journal : for cell and molecular biology 20120701

• Correlation of LINE-1 methylation levels in patient-matched buffy coat, serum, buccal cell, and bladder tumor tissue DNA samples.

  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20120701

• Epigenetic features of the mouse trophoblast.

  Reproductive biomedicine online 20120701

• Unique mutational profile associated with a loss of TDG expression in the rectal cancer of a patient with a constitutional PMS2 deficiency.

  DNA repair 20120701

• DNA methyltransferases1 (DNMT1) and 3a (DNMT3a) colocalize with GAD67-positive neurons in the GAD67-GFP mouse brain.

  The Journal of comparative neurology 20120615

• Chemical recognition and binding kinetics in a functionalized tunnel junction.

  Nanotechnology 20120615

• Reduction of DNA hydroxymethylation in the mouse kidney insulted by ischemia reperfusion.

  Biochemical and biophysical research communications 20120615

• A histone acetyltransferase regulates active DNA demethylation in Arabidopsis.

  Science (New York, N.Y.) 20120615

• Base-resolution analysis of 5-hydroxymethylcytosine in the mammalian genome.

  Cell 20120608

• PGC7 binds histone H3K9me2 to protect against conversion of 5mC to 5hmC in early embryos.

  Nature 20120603

• Increased recycling of polyamines is associated with global DNA hypomethylation in rheumatoid arthritis synovial fibroblasts.

  Arthritis and rheumatism 20120601

• Differential DNA methylation alterations in radiation-sensitive and -resistant cells.

  DNA and cell biology 20120601

• Bridging sequence diversity and tissue-specific expression by DNA methylation in genes of the mouse prolactin superfamily.

  Mammalian genome : official journal of the International Mammalian Genome Society 20120601

• RB1 mutations and second primary malignancies after hereditary retinoblastoma.

  Familial cancer 20120601

• Age-related increase in levels of 5-hydroxymethylcytosine in mouse hippocampus is prevented by caloric restriction.

  Current Alzheimer research 20120601

• The role of 5-hydroxymethylcytosine in aging and Alzheimer's disease: current status and prospects for future studies.

  Current Alzheimer research 20120601

• Oxidatively generated damage to DNA at 5-methylcytosine mispairs.

  Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20120601

• Establishment of epigenetic patterns in development.

  Chromosoma 20120601

• DMSO is a strong inducer of DNA hydroxymethylation in pre-osteoblastic MC3T3-E1 cells.

  Epigenetics 20120601

• Standardization and quality controls for the methylated DNA immunoprecipitation technique.

  Epigenetics 20120601

• Tet family proteins and 5-hydroxymethylcytosine in development and disease.

  Development (Cambridge, England) 20120601

• Going beyond five bases in DNA sequencing.

  Current opinion in structural biology 20120601

• New sequencing technique produces high-resolution map of 5-hydroxymethylcytosine.

  Epigenomics 20120601

• [Recent advance in DNA epigenetic modifications-the sixth base in the genome].

  Sheng li ke xue jin zhan [Progress in physiology] 20120601

• Exocyclic carbons adjacent to the N6 of adenine are targets for oxidation by the Escherichia coli adaptive response protein AlkB.

  Journal of the American Chemical Society 20120530

• Functions of DNA methylation: islands, start sites, gene bodies and beyond.

  Nature reviews. Genetics 20120529

• [Oxidation and deamination of nucleobases as an epigenetic tool].

  Postepy higieny i medycyny doswiadczalnej (Online) 20120524

• Quantitative sequencing of 5-methylcytosine and 5-hydroxymethylcytosine at single-base resolution.

  Science (New York, N.Y.) 20120518

• Hydroxylation of 5-methylcytosine by TET2 maintains the active state of the mammalian HOXA cluster.

  Nature communications 20120508

• A simple colorimetric detection of DNA methylation.

  The Analyst 20120507

• Mutation in NSUN2, which encodes an RNA methyltransferase, causes autosomal-recessive intellectual disability.

  American journal of human genetics 20120504

• Supratentorial and spinal pediatric ependymomas display a hypermethylated phenotype which includes the loss of tumor suppressor genes involved in the control of cell growth and death.

  Acta neuropathologica 20120501

• Recent advances in the molecular understanding of glioblastoma.

  Journal of neuro-oncology 20120501

• Heterologous expression and purification of Arabidopsis thaliana VIM1 protein: in vitro evidence for its inability to recognize hydroxymethylcytosine, a rare base in Arabidopsis DNA.

  Protein expression and purification 20120501

• Genomic organization and dynamics of repetitive DNA sequences in representatives of three Fagaceae genera.

  Genome 20120501

• required to maintain repression2 is a novel protein that facilitates locus-specific paramutation in maize.

  The Plant cell 20120501

• Genomic hypomethylation in the human germline associates with selective structural mutability in the human genome.

  PLoS genetics 20120501

• [Progress of research on 5-hydroxymethylcytosine].

  Yi chuan = Hereditas 20120501

• A conserved role for intragenic DNA methylation in alternative pre-mRNA splicing.

  Transcription 20120501

• A unique regulatory phase of DNA methylation in the early mammalian embryo.

  Nature 20120419

• Epiblast stem cell-based system reveals reprogramming synergy of germline factors.

  Cell stem cell 20120406

• Silencing of endogenous retroviruses: when and why do histone marks predominate?

  Trends in biochemical sciences 20120401

• Folic acid increases global DNA methylation and reduces inflammation to prevent Helicobacter-associated gastric cancer in mice.

  Gastroenterology 20120401

• The involvement of 5-hydroxymethylcytosine in active DNA demethylation in mice.

  Biology of reproduction 20120401

• Loss of 5-hydroxymethylcytosine is accompanied with malignant cellular transformation.

  Cancer science 20120401

• Thymine DNA glycosylase specifically recognizes 5-carboxylcytosine-modified DNA.

  Nature chemical biology 20120401

• 5-hydroxymethyl-cytosine enrichment of non-committed cells is not a universal feature of vertebrate development.

  Epigenetics 20120401

• DNA methylation profiling identifies epigenetic dysregulation in pancreatic islets from type 2 diabetic patients.

  The EMBO journal 20120321

• Quantitative measurement of genome-wide DNA methylation by a reliable and cost-efficient enzyme-linked immunosorbent assay technique.

  Analytical biochemistry 20120315

• Preparation of site-specific T=mCG cis-syn cyclobutane dimer-containing template and its error-free bypass by yeast and human polymerase η.

  The Journal of biological chemistry 20120309

• Focus on molecules: 5-methylcytosine, a possible epigenetic link between ageing and ocular disease.

  Experimental eye research 20120301

• Tissue type is a major modifier of the 5-hydroxymethylcytosine content of human genes.

  Genome research 20120301

• Conservation of Dcm-mediated cytosine DNA methylation in Escherichia coli.

  FEMS microbiology letters 20120301

• Role of TET2 mutations in myeloproliferative neoplasms.

  Current hematologic malignancy reports 20120301

• Hydroxylation mediates chromatin demethylation.

  Journal of biochemistry 20120301

• Direct analysis of 5-methylcytosine and 5-methyl-2'-deoxycytidine in human urine by isotope dilution LC-MS/MS: correlations with N-methylated purines and oxidized DNA lesions.

  Chemical research in toxicology 20120220

• Genome-wide DNA methylation level analysis by micellar electrokinetic chromatography and laser-induced fluorescence detection after treatment of cell lines with azacytidine and antifolates.

  Analytical biochemistry 20120215

• Inorganic arsenic in drinking water accelerates N-butyl-N-(4-hydroxybutyl)nitrosamine-induced bladder tissue damage in mice.

  Toxicology and applied pharmacology 20120215

• Methylation-dependent DNA restriction in Bacillus anthracis.

  Gene 20120215

• Structure-based mechanistic insights into DNMT1-mediated maintenance DNA methylation.

  Science (New York, N.Y.) 20120210

• A DNA 3' phosphatase functions in active DNA demethylation in Arabidopsis.

  Molecular cell 20120210

• Biochemical characterization of recombinant β-glucosyltransferase and analysis of global 5-hydroxymethylcytosine in unique genomes.

  Biochemistry 20120207

• Predictors of global methylation levels in blood DNA of healthy subjects: a combined analysis.

  International journal of epidemiology 20120201

• In utero exposures, infant growth, and DNA methylation of repetitive elements and developmentally related genes in human placenta.

  Environmental health perspectives 20120201

• Effects of exposure to soluble fraction of industrial solid waste on lipid peroxidation and DNA methylation in erythrocytes of Oreochromis niloticus, as assessed by quantification of MDA and m⁵dC rates.

  Ecotoxicology and environmental safety 20120201

• DNA glycosylases: in DNA repair and beyond.

  Chromosoma 20120201

• Light-regulated and cell-specific methylation of the maize PEPC promoter.

  Journal of experimental botany 20120201

• DNA methylation in repetitive elements and post-traumatic stress disorder: a case-control study of US military service members.

  Epigenomics 20120201

• The dynamics and prognostic potential of DNA methylation changes at stem cell gene loci in women's cancer.

  PLoS genetics 20120201

• Inhibition of MspI cleavage activity by hydroxymethylation of the CpG site: a concern for DNA modification studies using restriction endonucleases.

  Epigenetics 20120201

• Semi-quantitative immunohistochemical detection of 5-hydroxymethyl-cytosine reveals conservation of its tissue distribution between amphibians and mammals.

  Epigenetics 20120201

• Trophoblast-specific DNA methylation occurs after the segregation of the trophectoderm and inner cell mass in the mouse periimplantation embryo.

  Epigenetics 20120201

• Effects of TET2 mutations on DNA methylation in chronic myelomonocytic leukemia.

  Epigenetics 20120201

• Pull-down of 5-hydroxymethylcytosine DNA using JBP1-coated magnetic beads.

  Nature protocols 20120126

• Fabrication of duplex DNA microarrays incorporating methyl-5-cytosine.

  Lab on a chip 20120121

• The curious chemical biology of cytosine: deamination, methylation, and oxidation as modulators of genomic potential.

  ACS chemical biology 20120120

• Modulation of Wnt/β-catenin signaling and proliferation by a ferrous iron chelator with therapeutic efficacy in genetically engineered mouse models of cancer.

  Oncogene 20120112

• Mutations in epigenetic modifiers in myeloid malignancies and the prospect of novel epigenetic-targeted therapy.

  Advances in hematology 20120101

• Benzene metabolite 1,2,4-benzenetriol induces halogenated DNA and tyrosines representing halogenative stress in the HL-60 human myeloid cell line.

  Environmental health perspectives 20120101

• Growth arrest and DNA-damage-inducible, beta (GADD45b)-mediated DNA demethylation in major psychosis.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20120101

• Importance of methionine metabolism in morula-to-blastocyst transition in bovine preimplantation embryos.

  The Journal of reproduction and development 20120101

• In Posidonia oceanica cadmium induces changes in DNA methylation and chromatin patterning.

  Journal of experimental botany 20120101

• Development of a multiplex DNA-based traceability tool for crop plant materials.

  Analytical and bioanalytical chemistry 20120101

• DNA methylation testing and marker validation using PCR: diagnostic applications.

  Expert review of molecular diagnostics 20120101

• Epigenetic reprogramming in mouse pre-implantation development and primordial germ cells.

  Development (Cambridge, England) 20120101

• DNA methylation: TET proteins-guardians of CpG islands?

  EMBO reports 20120101

• Simultaneous single-molecule detection of endogenous C-5 DNA methylation and chromatin accessibility using MAPit.

  Methods in molecular biology (Clifton, N.J.) 20120101

• The HARE-HTH and associated domains: novel modules in the coordination of epigenetic DNA and protein modifications.

  Cell cycle (Georgetown, Tex.) 20120101

• Embryonic lethality in mice lacking mismatch-specific thymine DNA glycosylase is partially prevented by DOPS, a precursor of noradrenaline.

  The Tohoku journal of experimental medicine 20120101

• Aging and epigenetics: longitudinal changes in gene-specific DNA methylation.

  Epigenetics 20120101

• The (α-4) photoconjugates of 5-methylcytosine, 1,5-dimethylcytosine, 1-methylthymine and thymidine.

  Photochemistry and photobiology 20120101

• Inhibition of microRNA function by antimiR oligonucleotides.

  Silence 20120101

• The S. pombe histone H2A dioxygenase Ofd2 regulates gene expression during hypoxia.

  PloS one 20120101

• Biomarker robustness reveals the PDGF network as driving disease outcome in ovarian cancer patients in multiple studies.

  BMC systems biology 20120101

• Contribution of intragenic DNA methylation in mouse gametic DNA methylomes to establish oocyte-specific heritable marks.

  PLoS genetics 20120101

• Why do results conflict regarding the prognostic value of the methylation status in colon cancers? The role of the preservation method.

  BMC cancer 20120101

• Patterns of repeat-induced point mutation in transposable elements of basidiomycete fungi.

  Genome biology and evolution 20120101

• Dynamic DNA cytosine methylation in the Populus trichocarpa genome: tissue-level variation and relationship to gene expression.

  BMC genomics 20120101

• Defining the sister rat mammary tumor cell lines HH-16 cl.2/1 and HH-16.cl.4 as an in vitro cell model for Erbb2.

  PloS one 20120101

• Human Vav1 expression in hematopoietic and cancer cell lines is regulated by c-Myb and by CpG methylation.

  PloS one 20120101

• Locked nucleic acid flow cytometry-fluorescence in situ hybridization (LNA flow-FISH): a method for bacterial small RNA detection.

  Journal of visualized experiments : JoVE 20120101

• Low-mutation-rate, reduced-genome Escherichia coli: an improved host for faithful maintenance of engineered genetic constructs.

  Microbial cell factories 20120101

• Sensitive quantitative analysis of murine LINE1 DNA methylation using high resolution melt analysis.

  Epigenetics 20120101

• Bisulfite sequencing reveals that Aspergillus flavus holds a hollow in DNA methylation.

  PloS one 20120101

• Lysine methyltransferase G9a is not required for DNMT3A/3B anchoring to methylated nucleosomes and maintenance of DNA methylation in somatic cells.

  Epigenetics & chromatin 20120101

• Automated workflow for preparation of cDNA for cap analysis of gene expression on a single molecule sequencer.

  PloS one 20120101

• Bypass of cell cycle arrest induced by transient DNMT1 post-transcriptional silencing triggers aneuploidy in human cells.

  Cell division 20120101

• Oncolytic virotherapy for hematological malignancies.

  Advances in virology 20120101

• Overexpression of DNA damage-induced 45 α gene contributes to esophageal squamous cell cancer by promoter hypomethylation.

  Journal of experimental & clinical cancer research : CR 20120101

• Benzo[a]pyrene, aflatoxine B₁ and acetaldehyde mutational patterns in TP53 gene using a functional assay: relevance to human cancer aetiology.

  PloS one 20120101

• TET2 mutations are associated with specific 5-methylcytosine and 5-hydroxymethylcytosine profiles in patients with chronic myelomonocytic leukemia.

  PloS one 20120101

• Tet2 disruption leads to enhanced self-renewal and altered differentiation of fetal liver hematopoietic stem cells.

  Scientific reports 20120101

• Particulate matter Air Pollution induces hypermethylation of the p16 promoter Via a mitochondrial ROS-JNK-DNMT1 pathway.

  Scientific reports 20120101

• Sexual differentiation of the rodent brain: dogma and beyond.

  Frontiers in neuroscience 20120101

• DNA Methylation Fluctuation Induced by Virus Infection Differs between MD-resistant and -susceptible Chickens.

  Frontiers in genetics 20120101

• The effect of preconception paternal alcohol exposure on epigenetic remodeling of the h19 and rasgrf1 imprinting control regions in mouse offspring.

  Frontiers in genetics 20120101

• Cell-specific DNA methylation patterns of retina-specific genes.

  PloS one 20120101

• Integrated epigenome profiling of repressive histone modifications, DNA methylation and gene expression in normal and malignant urothelial cells.

  PloS one 20120101

• Insufficient maintenance DNA methylation is associated with abnormal embryonic development.

  BMC medicine 20120101

• Effect of aging on 5-hydroxymethylcytosine in the mouse hippocampus.

  Restorative neurology and neuroscience 20120101

• Prognostic value of three different methods of MGMT promoter methylation analysis in a prospective trial on newly diagnosed glioblastoma.

  PloS one 20120101

• Genetic divergence between freshwater and marine morphs of alewife (Alosa pseudoharengus): a 'next-generation' sequencing analysis.

  PloS one 20120101

• Hiwi mediated tumorigenesis is associated with DNA hypermethylation.

  PloS one 20120101

• High recovery of cell-free methylated DNA based on a rapid bisulfite-treatment protocol.

  BMC molecular biology 20120101

• Increased expression and altered methylation of HERVWE1 in the human placentas of smaller fetuses from monozygotic, dichorionic, discordant twins.

  PloS one 20120101

• Low-dose Cd induces hepatic gene hypermethylation, along with the persistent reduction of cell death and increase of cell proliferation in rats and mice.

  PloS one 20120101

• Modulating Anti-MicroRNA-21 Activity and Specificity Using Oligonucleotide Derivatives and Length Optimization.

  ISRN pharmaceutics 20120101

• Genome wide analysis of acute myeloid leukemia reveal leukemia specific methylome and subtype specific hypomethylation of repeats.

  PloS one 20120101

• Global DNA hypomethylation in peripheral blood leukocytes as a biomarker for cancer risk: a meta-analysis.

  PloS one 20120101

• Epigenetic factors in cancer risk: effect of chemical carcinogens on global DNA methylation pattern in human TK6 cells.

  PloS one 20120101

• Revised selection criteria for candidate restriction enzymes in genome walking.

  PloS one 20120101

• Epidemiological, genetic and epigenetic aspects of the research on healthy ageing and longevity.

  Immunity & ageing : I & A 20120101

• Epigenetic effects of stress and corticosteroids in the brain.

  Frontiers in cellular neuroscience 20120101

• The role of methylation in the intrinsic dynamics of B- and Z-DNA.

  PloS one 20120101

• The distribution of a germline methylation marker suggests a regional mechanism of LINE-1 silencing by the piRNA-PIWI system.

  BMC genetics 20120101

• Epigenetics and autoimmune diseases.

  Autoimmune diseases 20120101

• Nucleosomes correlate with in vivo progression pattern of de novo methylation of p16 CpG islands in human gastric carcinogenesis.

  PloS one 20120101

• Efficient reverse transcription using locked nucleic acid nucleotides towards the evolution of nuclease resistant RNA aptamers.

  PloS one 20120101

• Antiproliferative effects of DNA methyltransferase 3B depletion are not associated with DNA demethylation.

  PloS one 20120101

• Aphids: a model for polyphenism and epigenetics.

  Genetics research international 20120101

• Genetics: polymorphisms, epigenetics, and something in between.

  Genetics research international 20120101

• Crosstalk among Epigenetic Pathways Regulates Neurogenesis.

  Frontiers in neuroscience 20120101

• Long interspersed nuclear element-1 hypomethylation and oxidative stress: correlation and bladder cancer diagnostic potential.

  PloS one 20120101

• Genetics and epigenetics of Parkinson's disease.

  TheScientificWorldJournal 20120101

• The genetic and epigenetic journey of embryonic stem cells into mature neural cells.

  Frontiers in genetics 20120101

• Whole blood DNA aberrant methylation in pancreatic adenocarcinoma shows association with the course of the disease: a pilot study.

  PloS one 20120101

• Epigenetic Modifications during Angiosperm Gametogenesis.

  Frontiers in plant science 20120101

• Methylation-mediated molecular dysregulation in clinical oral malignancy.

  Journal of oncology 20120101

• Epigenetic dysregulation in laryngeal squamous cell carcinoma.

  Journal of oncology 20120101

• Bioactive dietary supplements reactivate ER expression in ER-negative breast cancer cells by active chromatin modifications.

  PloS one 20120101

• Thermodynamic Control of Small RNA-Mediated Gene Silencing.

  Frontiers in genetics 20120101

• The Role of Mitochondrial NADPH-Dependent Isocitrate Dehydrogenase in Cancer Cells.

  International journal of cell biology 20120101

• Enzymatic synthesis of DNA strands containing α-L-LNA (α-L-configured locked nucleic acid) thymine nucleotides.

  Artificial DNA, PNA & XNA 20120101

• 5-Methylcytosine and 5-hydroxymethylcytosine spatiotemporal profiles in the mouse zygote.

  PloS one 20120101

• Tackling skeletal muscle cells epigenome in the next-generation sequencing era.

  Comparative and functional genomics 20120101

• Dissecting epigenetic silencing complexity in the mouse lung cancer suppressor gene Cadm1.

  PloS one 20120101

• Decreased 5-hydroxymethylcytosine is associated with neural progenitor phenotype in normal brain and shorter survival in malignant glioma.

  PloS one 20120101

• Whole genome methylation profiling by immunoprecipitation of methylated DNA.

  Methods in molecular biology (Clifton, N.J.) 20120101

• Enzymatic analysis of Tet proteins: key enzymes in the metabolism of DNA methylation.

  Methods in enzymology 20120101

• AID enzymatic activity is inversely proportional to the size of cytosine C5 orbital cloud.

  PloS one 20120101

• Activation-induced cytidine deaminase alters the subcellular localization of Tet family proteins.

  PloS one 20120101

• Selective capture of 5-hydroxymethylcytosine from genomic DNA.

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• Neuronal activity modifies the DNA methylation landscape in the adult brain.

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• Association of hypomethylation of LINE-1 repetitive element in blood leukocyte DNA with an increased risk of hepatocellular carcinoma.

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• Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA.

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• TET family proteins and their role in stem cell differentiation and transformation.

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• Molecular biology. Demystifying DNA demethylation.

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• Reduced expression of DNMT3B in the germ cells of patients with bilateral spermatogenic arrest does not lead to changes in the global methylation status.

  Molecular human reproduction 20110901

• Detection of 5-hydroxymethylcytosine in a combined glycosylation restriction analysis (CGRA) using restriction enzyme Taq(α)I.

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• Inhibition of TET2-mediated conversion of 5-methylcytosine to 5-hydroxymethylcytosine disturbs erythroid and granulomonocytic differentiation of human hematopoietic progenitors.

  Blood 20110901

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  Cell research 20110901

• Analysis of the coding genome of diffuse large B-cell lymphoma.

  Nature genetics 20110901

• Genome size, GC percentage and 5mC level in the Indonesian coelacanth Latimeria menadoensis.

  Marine genomics 20110901

• DNA methylation profiling in nanochannels.

  Biomicrofluidics 20110901

• Emerging roles of TET proteins and 5-hydroxymethylcytosines in active DNA demethylation and beyond.

  Cell cycle (Georgetown, Tex.) 20110815

• Cytosine methylation regulates oviposition in the pathogenic blood fluke Schistosoma mansoni.

  Nature communications 20110809

• Discrimination between 5-hydroxymethylcytosine and 5-methylcytosine by a chemically designed peptide.

  Chemical communications (Cambridge, England) 20110807

• Tet1 is dispensable for maintaining pluripotency and its loss is compatible with embryonic and postnatal development.

  Cell stem cell 20110805

• Global DNA hypomethylation is an early event in Helicobacter pylori-related gastric carcinogenesis.

  Journal of clinical pathology 20110801

• Cellular DNA methylation program during neurulation and its alteration by alcohol exposure.

  Birth defects research. Part A, Clinical and molecular teratology 20110801

• Increased methylation variation in epigenetic domains across cancer types.

  Nature genetics 20110801

• Tet1 and 5-hydroxymethylation: a genome-wide view in mouse embryonic stem cells.

  Cell cycle (Georgetown, Tex.) 20110801

• Learning biomarkers of pluripotent stem cells in mouse.

  DNA research : an international journal for rapid publication of reports on genes and genomes 20110801

• Analysis of DNA methylation in a three-generation family reveals widespread genetic influence on epigenetic regulation.

  PLoS genetics 20110801

• Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers.

  Oncotarget 20110801

• New concepts of old epigenetic phenomena and their implications for selecting specific cell populations for epigenomic research.

  Epigenomics 20110801

• Genetics and mitochondrial abnormalities in autism spectrum disorders: a review.

  Current genomics 20110801

• Stemming epigenetics in marine stramenopiles.

  Current genomics 20110801

• The transposon-driven evolutionary origin and basis of histone deacetylase functions and limitations in disease prevention.

  Clinical epigenetics 20110801

• Epigenetic abnormalities in myeloproliferative neoplasms: a target for novel therapeutic strategies.

  Clinical epigenetics 20110801

• Differential effects of nutritional folic acid deficiency and moderate hyperhomocysteinemia on aortic plaque formation and genome-wide DNA methylation in vascular tissue from ApoE-/- mice.

  Clinical epigenetics 20110801

• Detection of 5-hydroxymethylcytosine in DNA by transferring a keto-glucose by using T4 phage β-glucosyltransferase.

  Chembiochem : a European journal of chemical biology 20110725

• The discovery of 5-formylcytosine in embryonic stem cell DNA.

  Angewandte Chemie (International ed. in English) 20110725

• The presence of 5-hydroxymethylcytosine at the gene promoter and not in the gene body negatively regulates gene expression.

  Biochemical and biophysical research communications 20110722

• Hypomethylation of LINE-1 but not Alu in lymphocyte subsets of systemic lupus erythematosus patients.

  Clinica chimica acta; international journal of clinical chemistry 20110715

• Tissue-specific distribution and dynamic changes of 5-hydroxymethylcytosine in mammalian genomes.

  The Journal of biological chemistry 20110715

• 5-Hydroxymethylcytosine, the sixth base of the genome.

  Angewandte Chemie (International ed. in English) 20110711

• Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair.

  Cell 20110708

• Prolonged exposure to particulate pollution, genes associated with glutathione pathways, and DNA methylation in a cohort of older men.

  Environmental health perspectives 20110701

• Recurrent DNMT3A mutations in patients with myelodysplastic syndromes.

  Leukemia 20110701

• Hypothesis: environmental regulation of 5-hydroxymethylcytosine by oxidative stress.

  Epigenetics 20110701

• Syntheses of 5-formyl- and 5-carboxyl-dC containing DNA oligos as potential oxidation products of 5-hydroxymethylcytosine in DNA.

  Organic letters 20110701

• Long dwell-time passage of DNA through nanometer-scale pores: kinetics and sequence dependence of motion.

  Biophysical journal 20110622

• Analysis of global DNA methylation by hydrophilic interaction ultra high-pressure liquid chromatography tandem mass spectrometry.

  Analytical biochemistry 20110615

• Loss of a single Hic1 allele accelerates polyp formation in Apc(Δ716) mice.

  Oncogene 20110609

• Facile synthesis of hydroxymethylcytosine-containing oligonucleotides and their reactivity upon osmium oxidation.

  Organic & biomolecular chemistry 20110607

• Global DNA methylation in the mouse liver is affected by methyl deficiency and arsenic in a sex-dependent manner.

  Archives of toxicology 20110601

• Reconstructing the ancestral germ line methylation state of young repeats.

  Molecular biology and evolution 20110601

• Analysis of associations between the patterns of global DNA hypomethylation and expression of DNA methyltransferase in patients with systemic lupus erythematosus.

  International journal of dermatology 20110601

• CNG site-specific and methyl-sensitive endonuclease WEN1 from wheat seedlings.

  Biochemistry. Biokhimiia 20110601

• Integrating 5-hydroxymethylcytosine into the epigenomic landscape of human embryonic stem cells.

  PLoS genetics 20110601

• Epigenetic changes of serotonin transporter in the patients with alcohol dependence: methylation of an serotonin transporter promoter CpG island.

  Psychiatry investigation 20110601

• Schizophrenia: redox regulation and volume neurotransmission.

  Current neuropharmacology 20110601

• DNA methylation and demethylation in mammals.

  The Journal of biological chemistry 20110527

• Epigenetically silenced miR-34b/c as a novel faecal-based screening marker for colorectal cancer.

  British journal of cancer 20110524

• Syntheses of two 5-hydroxymethyl-2'-deoxycytidine phosphoramidites with TBDMS as the 5-hydroxymethyl protecting group and their incorporation into DNA.

  The Journal of organic chemistry 20110520

• Genome-wide regulation of 5hmC, 5mC, and gene expression by Tet1 hydroxylase in mouse embryonic stem cells.

  Molecular cell 20110520

• Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells.

  Nature 20110519

• Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation.

  Nature 20110519

• TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity.

  Nature 20110519

• Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells.

  Nature 20110519

• Epigenetics: Tet proteins in the limelight.

  Nature 20110519

• A sensitive mass spectrometry method for simultaneous quantification of DNA methylation and hydroxymethylation levels in biological samples.

  Analytical biochemistry 20110515

• Hydroxylation of methylated CpG dinucleotides reverses stabilisation of DNA duplexes by cytosine 5-methylation.

  Chemical communications (Cambridge, England) 20110514

• Advances in DNA methylation: 5-hydroxymethylcytosine revisited.

  Clinica chimica acta; international journal of clinical chemistry 20110512

• Theoretical determination of one-electron redox potentials for DNA bases, base pairs, and stacks.

  The journal of physical chemistry. A 20110512

• Dependence of substrate binding and catalysis on pH, ionic strength, and temperature for thymine DNA glycosylase: Insights into recognition and processing of G·T mispairs.

  DNA repair 20110505

• Enzymatic labeling of 5-hydroxymethylcytosine in DNA.

  Angewandte Chemie (International ed. in English) 20110502

• Epigenetic alterations in liver of C57BL/6J mice after short-term inhalational exposure to 1,3-butadiene.

  Environmental health perspectives 20110501

• Effects of short-term exposure to inhalable particulate matter on telomere length, telomerase expression, and telomerase methylation in steel workers.

  Environmental health perspectives 20110501

• Detection of global DNA methylation and paternally imprinted H19 gene methylation in preeclamptic placentas.

  Hypertension research : official journal of the Japanese Society of Hypertension 20110501

• In sickness and in health: the role of methyl-CpG binding protein 2 in the central nervous system.

  The European journal of neuroscience 20110501

• Characterisation of DNA methylation status using spectroscopy (mid-IR versus Raman) with multivariate analysis.

  Journal of biophotonics 20110501

• Determination of genomic 5-hydroxymethyl-2'-deoxycytidine in human DNA by capillary electrophoresis with laser induced fluorescence.

  Epigenetics 20110501

• Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain.

  Cell 20110429

• Phosphopeptides designed for 5-methylcytosine recognition.

  Biochemistry 20110426

• Quantum mechanics study and Monte Carlo simulation on the hydrolytic deamination of 5-methylcytosine glycol.

  Physical chemistry chemical physics : PCCP 20110414

• Methylation and demethylation of the Arabidopsis genome.

  Current opinion in plant biology 20110401

• Analysis of global methylation using a Zta-expressing nasopharyngeal carcinoma cell line.

  Genomics 20110401

• (-)-Epigallocatechin-3-gallate reactivates silenced tumor suppressor genes, Cip1/p21 and p16INK4a, by reducing DNA methylation and increasing histones acetylation in human skin cancer cells.

  Carcinogenesis 20110401

• Placental development during early pregnancy in sheep: cell proliferation, global methylation, and angiogenesis in the fetal placenta.

  Reproduction (Cambridge, England) 20110401

• Identification of restriction endonucleases sensitive to 5-cytosine methylation at non-CpG sites, including expanded (CAG)n/(CTG)n repeats.

  Epigenetics 20110401

• Preparation of reduced representation bisulfite sequencing libraries for genome-scale DNA methylation profiling.

  Nature protocols 20110401

• Strategies for DNA methylation analysis in developmental studies.

  Development, growth & differentiation 20110401

• Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells.

  Genes & development 20110401

• Diet, nutrition and modulation of genomic expression in fetal origins of adult disease.

  Journal of nutrigenetics and nutrigenomics 20110401

• [Active DNA demethylation in mammals].

  Yi chuan = Hereditas 20110401

• A sustained dietary change increases epigenetic variation in isogenic mice.

  PLoS genetics 20110401

• [Determination of global DNA methylation in tissues by hydrophilic interaction liquid chromatography].

  Se pu = Chinese journal of chromatography 20110401

• The structural basis for selective binding of non-methylated CpG islands by the CFP1 CXXC domain.

  Nature communications 20110308

• Disulfiram is a DNA demethylating agent and inhibits prostate cancer cell growth.

  The Prostate 20110301

• Drought-induced site-specific DNA methylation and its association with drought tolerance in rice (Oryza sativa L.).

  Journal of experimental botany 20110301

• Molecular characterization of late stomal recurrence following total laryngectomy.

  Oncology reports 20110301

• A twin approach to unraveling epigenetics.

  Trends in genetics : TIG 20110301

• Inborn and acquired metabolic defects in cancer.

  Journal of molecular medicine (Berlin, Germany) 20110301

• Regulation and function of DNA methylation in plants and animals.

  Cell research 20110301

• Different types of plant chromatin associated with modified histones H3 and H4 and methylated DNA.

  Genetica 20110301

• Rotational position of a 5-methylcytosine-containing cyclobutane pyrimidine dimer in a nucleosome greatly affects its deamination rate.

  The Journal of biological chemistry 20110225

• Methyltransferase-directed derivatization of 5-hydroxymethylcytosine in DNA.

  Angewandte Chemie (International ed. in English) 20110225

• Bisulfite-free analysis of 5MeC-binding proteins and locus-specific methylation density using a microparticle-based flow cytometry assay.

  The Analyst 20110221

• Embryonic lethal phenotype reveals a function of TDG in maintaining epigenetic stability.

  Nature 20110217

• ALKBH3, a human AlkB homologue, contributes to cell survival in human non-small-cell lung cancer.

  British journal of cancer 20110215

• Anthraquinone-sensitized photooxidation of 5-methylcytosine in DNA leading to piperidine-induced efficient strand cleavage.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20110211

• Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells.

  Cell stem cell 20110204

• MGMT promoter hypermethylation is a frequent, early, and consistent event in astrocytoma progression, and not correlated with TP53 mutation.

  Journal of neuro-oncology 20110201

• Comprehensive analysis of DNA-methylation in mammalian tissues using MeDIP-chip.

  Methods (San Diego, Calif.) 20110201

• MIRA-SNuPE, a quantitative, multiplex method for measuring allele-specific DNA methylation.

  Epigenetics 20110201

• Nucleosomes containing methylated DNA stabilize DNA methyltransferases 3A/3B and ensure faithful epigenetic inheritance.

  PLoS genetics 20110201

• Novel DNA binding domain-based assays for detection of methylated and nonmethylated DNA.

  Epigenomics 20110201

• Discrimination of methylcytosine from hydroxymethylcytosine in DNA molecules.

  Journal of the American Chemical Society 20110126

• Pyrimidine-pyrimidine base pairs stabilized by silver(I) ions.

  Chemical communications (Cambridge, England) 20110121

• Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases.

  Cancer cell 20110118

• A dual flip-out mechanism for 5mC recognition by the Arabidopsis SUVH5 SRA domain and its impact on DNA methylation and H3K9 dimethylation in vivo.

  Genes & development 20110115

• Alu and Satα hypomethylation in Helicobacter pylori-infected gastric mucosae.

  International journal of cancer 20110101

• In vivo, in vitro, and in silico analysis of methylation of the HIV-1 provirus.

  Methods (San Diego, Calif.) 20110101

• Physiological and biochemical aspects of hydroxylations and demethylations catalyzed by human 2-oxoglutarate oxygenases.

  Trends in biochemical sciences 20110101

• Stable transmission of reversible modifications: maintenance of epigenetic information through the cell cycle.

  Cellular and molecular life sciences : CMLS 20110101

• Comparison of methyl-DNA immunoprecipitation (MeDIP) and methyl-CpG binding domain (MBD) protein capture for genome-wide DNA methylation analysis reveal CpG sequence coverage bias.

  Epigenetics 20110101

• Global DNA methylation measurement by HPLC using low amounts of DNA.

  Biotechnology journal 20110101

• Evaluation of methylation degree from formalin-fixed paraffin-embedded DNA extract by field-amplified sample injection capillary electrophoresis with UV detection.

  Analytical and bioanalytical chemistry 20110101

• Functional conservation of nucleosome formation selectively biases presumably neutral molecular variation in yeast genomes.

  Genome biology and evolution 20110101

• DNA methylation and cancer.

  Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques 20110101

• DNA repair and the control of DNA methylation.

  Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques 20110101

• Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine.

  Nature biotechnology 20110101

• Comprehensive profiling of zebrafish hepatic proximal promoter CpG island methylation and its modification during chemical carcinogenesis.

  BMC genomics 20110101

• Construction and application for QTL analysis of a Restriction Site Associated DNA (RAD) linkage map in barley.

  BMC genomics 20110101

• The tendency to recreate ancestral CG dinucleotides in the human genome.

  BMC evolutionary biology 20110101

• The genome sequence of E. coli W (ATCC 9637): comparative genome analysis and an improved genome-scale reconstruction of E. coli.

  BMC genomics 20110101

• Systematic evaluation of genome-wide methylated DNA enrichment using a CpG island array.

  BMC genomics 20110101

• Deciphering squamous cell carcinoma using multidimensional genomic approaches.

  Journal of skin cancer 20110101

• DNA methylation-mediated control of learning and memory.

  Molecular brain 20110101

• Discovery pipeline for epigenetically deregulated miRNAs in cancer: integration of primary miRNA transcription.

  BMC genomics 20110101

• Human AlkB homologue 5 is a nuclear 2-oxoglutarate dependent oxygenase and a direct target of hypoxia-inducible factor 1α (HIF-1α).

  PloS one 20110101

• Characterization of Eu- and heterochromatin of citrus with a focus on the condensation behavior of 45S rDNA chromatin.

  Cytogenetic and genome research 20110101

• ReadDepth: a parallel R package for detecting copy number alterations from short sequencing reads.

  PloS one 20110101

• High sensitivity 5-hydroxymethylcytosine detection in Balb/C brain tissue.

  Journal of visualized experiments : JoVE 20110101

• Methylation at global LINE-1 repeats in human blood are affected by gender but not by age or natural hormone cycles.

  PloS one 20110101

• Different binding properties and function of CXXC zinc finger domains in Dnmt1 and Tet1.

  PloS one 20110101

• 2-hydroxyglutarate production, but not dominant negative function, is conferred by glioma-derived NADP-dependent isocitrate dehydrogenase mutations.

  PloS one 20110101

• Specific age-associated DNA methylation changes in human dermal fibroblasts.

  PloS one 20110101

• The properties and applications of single-molecule DNA sequencing.

  Genome biology 20110101

• Exploiting CpG hypermutability to identify phenotypically significant variation within human protein-coding genes.

  Genome biology and evolution 20110101

• Induction of cyclooxygenase-2 expression by hepatitis B virus depends on demethylation-associated recruitment of transcription factors to the promoter.

  Virology journal 20110101

• 5-Hydroxymethylcytosine in the mammalian zygote is linked with epigenetic reprogramming.

  Nature communications 20110101

• Genome wide SNP discovery, analysis and evaluation in mallard (Anas platyrhynchos).

  BMC genomics 20110101

• Rare and frequent promoter methylation, respectively, of TSHZ2 and 3 genes that are both downregulated in expression in breast and prostate cancers.

  PloS one 20110101

• Proteomic analysis of the marine diatom Thalassiosira pseudonana upon exposure to benzo(a)pyrene.

  BMC genomics 20110101

• Parental ages and levels of DNA methylation in the newborn are correlated.

  BMC medical genetics 20110101

• Phenobarbital mediates an epigenetic switch at the constitutive androstane receptor (CAR) target gene Cyp2b10 in the liver of B6C3F1 mice.

  PloS one 20110101

• Branched RNA: A New Architecture for RNA Interference.

  Journal of nucleic acids 20110101

• Proximity ligation in situ assay for monitoring the global DNA methylation in cells.

  BMC biotechnology 20110101

• Down-regulation of UHRF1, associated with re-expression of tumor suppressor genes, is a common feature of natural compounds exhibiting anti-cancer properties.

  Journal of experimental & clinical cancer research : CR 20110101

• Do DNA-methylation and histone acetylation play a role in clear cell renal carcinoma? Analysis of radical nephrectomy specimens in a long-term follow-up.

  International journal of immunopathology and pharmacology 20110101

• DNA methylation in Drosophila--a critical evaluation.

  Progress in molecular biology and translational science 20110101

• Opened-ring adducts of 5-methylcytosine and 1,5-dimethylcytosine with amines and water and evidence for an opened-ring hydrate of 2'-deoxycytidine.

  Photochemistry and photobiology 20110101

• Epigenetic regulation of satellite cell activation during muscle regeneration.

  Stem cell research & therapy 20110101

• Expression patterns and miRNA regulation of DNA methyltransferases in chicken primordial germ cells.

  PloS one 20110101

• Heterochromatic genes undergo epigenetic changes and escape silencing in immunodeficiency, centromeric instability, facial anomalies (ICF) syndrome.

  PloS one 20110101

• Wolbachia prophage DNA adenine methyltransferase genes in different Drosophila-Wolbachia associations.

  PloS one 20110101

• Genome-wide mapping of DNA methylation in chicken.

  PloS one 20110101

• A robust, simple genotyping-by-sequencing (GBS) approach for high diversity species.

  PloS one 20110101

• Bioinformatic prediction of ultraviolet light mutagenesis sensitivity of human genes and a method for genetically engineering UVB resistance.

  Cancer informatics 20110101

• Microarray evidences the role of pathologic adipose tissue in insulin resistance and their clinical implications.

  Journal of obesity 20110101

• Methylation levels of the 'long interspersed nucleotide element-1' repetitive sequences predict survival of melanoma patients.

  Journal of translational medicine 20110101

• PKC isoforms interact with and phosphorylate DNMT1.

  BMC biology 20110101

• Epigenetics of early child development.

  Frontiers in psychiatry 20110101

• Epigenomics of human embryonic stem cells and induced pluripotent stem cells: insights into pluripotency and implications for disease.

  Genome medicine 20110101

• Global acetylation and methylation changes predict papillary urothelial neoplasia of low malignant potential recurrence: a quantitative analysis.

  International journal of immunopathology and pharmacology 20110101

• Zeranol down-regulates p53 expression in primary cultured human breast cancer epithelial cells through epigenetic modification.

  International journal of molecular sciences 20110101

• Changes in global gene expression in response to chemical and genetic perturbation of chromatin structure.

  PloS one 20110101

• Renal kallikrein excretion and epigenetics in human acute kidney injury: expression, mechanisms and consequences.

  BMC nephrology 20110101

• Balancing selection is common in the extended MHC region but most alleles with opposite risk profile for autoimmune diseases are neutrally evolving.

  BMC evolutionary biology 20110101

• 5-Hydroxymethylcytosine is associated with enhancers and gene bodies in human embryonic stem cells.

  Genome biology 20110101

• Regulation of Pax6 by CTCF during induction of mouse ES cell differentiation.

  PloS one 20110101

• Substitution rate variation at human CpG sites correlates with non-CpG divergence, methylation level and GC content.

  Genome biology 20110101

• Use of specific chemical reagents for detection of modified nucleotides in RNA.

  Journal of nucleic acids 20110101

• Recognition of 5-hydroxymethylcytosine by the Uhrf1 SRA domain.

  PloS one 20110101

• [Cytosine methylation in DNA and its role in cancer therapy].

  Postepy biochemii 20110101

• 2'-O,4'-C-methyleneoxymethylene bridged nucleic acids (2',4'-BNA(COC)).

  Methods in molecular biology (Clifton, N.J.) 20110101

• The role of epigenetic alterations in papillary thyroid carcinogenesis.

  Journal of thyroid research 20110101

• On-chip DNA methylation analysis using osmium complexation.

  Journal of nucleic acids 20110101

• Distribution of 5-hydroxymethylcytosine in different human tissues.

  Journal of nucleic acids 20110101

• Signaling from the cytoplasm to the nucleus in striatal medium-sized spiny neurons.

  Frontiers in neuroanatomy 20110101

• Early in vitro differentiation of mouse definitive endoderm is not correlated with progressive maturation of nuclear DNA methylation patterns.

  PloS one 20110101

• New insights in the removal of the hydantoins, oxidation product of pyrimidines, via the base excision and nucleotide incision repair pathways.

  PloS one 20110101

• Enhanced chromatin accessibility and recruitment of JUNB mediate the sustained IL-4 expression in NFAT1 deficient T helper 2 cells.

  PloS one 20110101

• Epigenetic silencing of nucleolar rRNA genes in Alzheimer's disease.

  PloS one 20110101

• Long term transcriptional reactivation of epigenetically silenced genes in colorectal cancer cells requires DNA hypomethylation and histone acetylation.

  PloS one 20110101

• CpG islands undermethylation in human genomic regions under selective pressure.

  PloS one 20110101

• Identification of imprinted genes subject to parent-of-origin specific expression in Arabidopsis thaliana seeds.

  BMC plant biology 20110101

• Epigenetic therapy for breast cancer.

  International journal of molecular sciences 20110101

• Genomic analysis of parent-of-origin allelic expression in Arabidopsis thaliana seeds.

  PloS one 20110101

• Gene expression profiling: identification of genes with altered expression in Ayu17-449 knockout mice.

  Genetics and molecular research : GMR 20110101

• DNA methylation of SPARC and chronic low back pain.

  Molecular pain 20110101

• Epigenetic regulation of caloric restriction in aging.

  BMC medicine 20110101

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• Testing the FMR1 promoter for mosaicism in DNA methylation among CpG sites, strands, and cells in FMR1-expressing males with fragile X syndrome.

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• Differential methylation of the HPV 16 upstream regulatory region during epithelial differentiation and neoplastic transformation.

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• Current findings for recurring mutations in acute myeloid leukemia.

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• Silver nanoparticles embedded in zeolite membranes: release of silver ions and mechanism of antibacterial action.

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  Stem cells international 20110101

• GSTP1 DNA methylation and expression status is indicative of 5-aza-2'-deoxycytidine efficacy in human prostate cancer cells.

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• High resolution profiling of human exon methylation by liquid hybridization capture-based bisulfite sequencing.

  BMC genomics 20110101

• Increased copy number for methylated maternal 15q duplications leads to changes in gene and protein expression in human cortical samples.

  Molecular autism 20110101

• Batch effect correction for genome-wide methylation data with Illumina Infinium platform.

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• 5-Hydroxymethylcytosine: a new kid on the epigenetic block?

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• Epigenetics in prostate cancer.

  Prostate cancer 20110101

• Single cell analysis facilitates staging of Blimp1-dependent primordial germ cells derived from mouse embryonic stem cells.

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• A refined, rapid and reproducible high resolution melt (HRM)-based method suitable for quantification of global LINE-1 repetitive element methylation.

  BMC research notes 20110101

• Activation-induced cytidine deaminase expression in CD4+ T cells is associated with a unique IL-10-producing subset that increases with age.

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• Is There a Relationship between DNA Methylation and Phenotypic Plasticity in Invertebrates?

  Frontiers in physiology 20110101

• A concise review on epigenetic regulation: insight into molecular mechanisms.

  International journal of molecular sciences 20110101

• Development of an oral form of azacytidine: 2'3'5'triacetyl-5-azacytidine.

  Chemotherapy research and practice 20110101

• DNA methylation: a timeline of methods and applications.

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• Epigenomics in environmental health.

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• Epigenetics: a new challenge in the post-genomic era of livestock.

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• Profiling ascidian promoters as the primordial type of vertebrate promoter.

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• Impact of DNA methylation on trophoblast function.

  Clinical epigenetics 20110101

• Suffocating cancer: hypoxia-associated epimutations as targets for cancer therapy.

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• The stem cell state in plant development and in response to stress.

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  Organic letters 20101217

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• Global DNA methylation: comparison of enzymatic- and non-enzymatic-based methods.

  Clinical chemistry and laboratory medicine 20101201

• Conflicts targeting epigenetic systems and their resolution by cell death: novel concepts for methyl-specific and other restriction systems.

  DNA research : an international journal for rapid publication of reports on genes and genomes 20101201

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  Analytical chemistry 20101201

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  Cell research 20101201

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• Stromal fibroblasts in digestive cancer.

  Cancer microenvironment : official journal of the International Cancer Microenvironment Society 20101201

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• DNA methylation profiling using live-cell imaging.

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• Negative energy balance and hepatic gene expression patterns in high-yielding dairy cows during the early postpartum period: a global approach.

  Physiological genomics 20101101

• Microsatellite instability in Arabidopsis increases with plant development.

  Plant physiology 20101101

• Twenty-eight divergent polysaccharide loci specifying within- and amongst-strain capsule diversity in three strains of Bacteroides fragilis.

  Microbiology (Reading, England) 20101101

• DNA sequencing: detecting methylation with force.

  Nature nanotechnology 20101101

• The DNA methylome of human peripheral blood mononuclear cells.

  PLoS biology 20101101

• CTCF-dependent chromatin bias constitutes transient epigenetic memory of the mother at the H19-Igf2 imprinting control region in prospermatogonia.

  PLoS genetics 20101101

• The parental non-equivalence of imprinting control regions during mammalian development and evolution.

  PLoS genetics 20101101

• Epigenetic reprogramming in plant and animal development.

  Science (New York, N.Y.) 20101029

• Exome sequencing: the sweet spot before whole genomes.

  Human molecular genetics 20101015

• Carcinoma in situ testis displays permissive chromatin modifications similar to immature foetal germ cells.

  British journal of cancer 20101012

• Direct electrochemical detection of DNA methylation for retinoblastoma and CpG fragments using a nanocarbon film.

  Analytical biochemistry 20101001

• Cytidine deaminases: AIDing DNA demethylation?

  Genes & development 20101001

• Advances in genome-wide DNA methylation analysis.

  BioTechniques 20101001

• Function and detection of 5-methylcytosine in eukaryotic RNA.

  Epigenomics 20101001

• DNMT3L modulates significant and distinct flanking sequence preference for DNA methylation by DNMT3A and DNMT3B in vivo.

  PLoS genetics 20100901

• Orphan CpG islands identify numerous conserved promoters in the mammalian genome.

  PLoS genetics 20100901

• Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification.

  Nature 20100826

• Solid-phase synthesis of oligodeoxynucleotides containing N4-[2-(t-butyldisulfanyl)ethyl]-5-methylcytosine moieties.

  Molecules (Basel, Switzerland) 20100818

• Ischemia dysregulates DNA methyltransferases and p16INK4a methylation in human colorectal cancer cells.

  Epigenetics 20100816

• Mutual relationship between stacking and hydrogen bonding in DNA. Theoretical study of guanine-cytosine, guanine-5-methylcytosine, and their dimers.

  The journal of physical chemistry. B 20100812

• Presence of 5-methylcytosine in CpNpG trinucleotides in the human genome.

  Genomics 20100801

• Tobacco mosaic virus infection results in an increase in recombination frequency and resistance to viral, bacterial, and fungal pathogens in the progeny of infected tobacco plants.

  Plant physiology 20100801

• An alignment algorithm for bisulfite sequencing using the Applied Biosystems SOLiD System.

  Bioinformatics (Oxford, England) 20100801

• Identification of novel methylation markers in hepatocellular carcinoma using a methylation array.

  Journal of Korean medical science 20100801

• MLL2 is required in oocytes for bulk histone 3 lysine 4 trimethylation and transcriptional silencing.

  PLoS biology 20100801

• Methylation-independent DNA binding modulates specificity of Repressor of Silencing 1 (ROS1) and facilitates demethylation in long substrates.

  The Journal of biological chemistry 20100723

• Quantification of the sixth DNA base hydroxymethylcytosine in the brain.

  Angewandte Chemie (International ed. in English) 20100719

• Dysregulation of p53/Sp1 control leads to DNA methyltransferase-1 overexpression in lung cancer.

  Cancer research 20100715

• UHRF1 is a novel diagnostic marker of lung cancer.

  British journal of cancer 20100713

• Regulation of the expression of plant resistance gene SNC1 by a protein with a conserved BAT2 domain.

  Plant physiology 20100701

• Bisulfite sequencing of DNA.

  Current protocols in molecular biology 20100701

• DNA replication factor C1 mediates genomic stability and transcriptional gene silencing in Arabidopsis.

  The Plant cell 20100701

• A convenient spectrometric assay system for intracellular quantitative measurement of DNA glycosylase activity.

  Acta biochimica et biophysica Sinica 20100615

• Dynamic link of DNA demethylation, DNA strand breaks and repair in mouse zygotes.

  The EMBO journal 20100602

• Biomarkers of lead exposure and DNA methylation within retrotransposons.

  Environmental health perspectives 20100601

• Strategies for detecting genomic DNA methylation: a survey of US patents.

  Recent patents on DNA & gene sequences 20100601

• Novel mutations and their functional and clinical relevance in myeloproliferative neoplasms: JAK2, MPL, TET2, ASXL1, CBL, IDH and IKZF1.

  Leukemia 20100601

• siRNA-mediated methylation of Arabidopsis telomeres.

  PLoS genetics 20100601

• One-carbon metabolism and Alzheimer's disease: focus on epigenetics.

  Current genomics 20100601

• Tracing the derivation of embryonic stem cells from the inner cell mass by single-cell RNA-Seq analysis.

  Cell stem cell 20100507

• [The deciphering of the fifth DNA base. The human methylome].

  Pharmazie in unserer Zeit 20100501

• Radicals in 5-methylcytosine induced by ionizing radiation. Electron magnetic resonance for structural and mechanistic analyses.

  Radiation research 20100501

• Detection of genomic DNA methylation with denaturing high performance liquid chromatography.

  Human cell 20100501

• Oxidation reactions of cytosine DNA components by hydroxyl radical and one-electron oxidants in aerated aqueous solutions.

  Accounts of chemical research 20100420

• CyDNA: synthesis and replication of highly Cy-dye substituted DNA by an evolved polymerase.

  Journal of the American Chemical Society 20100414

• Enzymatic approaches and bisulfite sequencing cannot distinguish between 5-methylcytosine and 5-hydroxymethylcytosine in DNA.

  BioTechniques 20100401

• Quantification of leukocyte genomic 5-methylcytosine levels reveals epigenetic plasticity in healthy adult cloned cattle.

  Cellular reprogramming 20100401

• Bisulfite methylation profiling of large genomes.

  Epigenomics 20100401

• Hypomethylation of repeated DNA sequences in cancer.

  Epigenomics 20100401

• DNA methylation-mediated down-regulation of DNA methyltransferase-1 (DNMT1) is coincident with, but not essential for, global hypomethylation in human placenta.

  The Journal of biological chemistry 20100326

• A new photoproduct of 5-methylcytosine and adenine characterized by high-performance liquid chromatography and mass spectrometry.

  Chemical research in toxicology 20100315

• Synthesis and biophysical evaluation of 2',4'-constrained 2'O-methoxyethyl and 2',4'-constrained 2'O-ethyl nucleic acid analogues.

  The Journal of organic chemistry 20100305

• Evidence that localized variation in primate sequence divergence arises from an influence of nucleosome placement on DNA repair.

  Molecular biology and evolution 20100301

• Association of low-dose exposure to persistent organic pollutants with global DNA hypomethylation in healthy Koreans.

  Environmental health perspectives 20100301

• Breast cancer epigenetics: from DNA methylation to microRNAs.

  Journal of mammary gland biology and neoplasia 20100301

• From monogenic to polygenic obesity: recent advances.

  European child & adolescent psychiatry 20100301

• Chromosome and DNA methylation dynamics during meiosis in the autotetraploid Arabidopsis arenosa.

  Sexual plant reproduction 20100301

• Global DNA methylation changes in blood of patients with essential hypertension.

  Medical science monitor : international medical journal of experimental and clinical research 20100301

• [Effect of napthalene on the DNA methylation patterns and level in rice (Oryza sativa L.)].

  Huan jing ke xue= Huanjing kexue 20100301

• Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency.

  Nature 20100225

• Characterisation of CpG methylation in the upstream control region of mouse Nat2: evidence for a gene-environment interaction in a polymorphic gene implicated in folate metabolism.

  Gene 20100215

• Phosphorus and osmium as elemental tags for the determination of global DNA methylation--a novel application of high performance liquid chromatography inductively coupled plasma mass spectrometry in epigenetic studies.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100215

• Dnmt3 and G9a cooperate for tissue-specific development in zebrafish.

  The Journal of biological chemistry 20100205

• DNA methylation pattern changes upon long-term culture and aging of human mesenchymal stromal cells.

  Aging cell 20100201

• Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus.

  Genome research 20100201

• A new nuclear function of the Entamoeba histolytica glycolytic enzyme enolase: the metabolic regulation of cytosine-5 methyltransferase 2 (Dnmt2) activity.

  PLoS pathogens 20100201

• Age-associated epigenetic modifications in human DNA increase its immunogenicity.

  Aging 20100201

• The Janus face of DNA methylation in aging.

  Aging 20100201

• Electroanalytical study of SYBR Green I and ethidium bromide intercalation in methylated and unmethylated amplicons.

  Analytica chimica acta 20100111

• DNA methylation in diploid inbred lines of potatoes and its possible role in the regulation of heterosis.

  TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik 20100101

• Impaired active demethylation of the paternal genome in pronuclear-stage rat zygotes produced by in vitro fertilization or intracytoplasmic sperm injection.

  Molecular reproduction and development 20100101

• Distribution of DNA methylation, CpGs, and CpG islands in human isochores.

  Genomics 20100101

• Analysis of a c0t-1 library enables the targeted identification of minisatellite and satellite families in Beta vulgaris.

  BMC plant biology 20100101

• Characterization of nucleotide misincorporation patterns in the iceman's mitochondrial DNA.

  PloS one 20100101

• Genetic-epigenetic intersection in trophoblast differentiation: implications for extraembryonic tissue function.

  Epigenetics 20100101

• Genetic dissection of differential signaling threshold requirements for the Wnt/beta-catenin pathway in vivo.

  PLoS genetics 20100101

• Role for DNA methylation in the regulation of miR-200c and miR-141 expression in normal and cancer cells.

  PloS one 20100101

• Mild folate deficiency induces genetic and epigenetic instability and phenotype changes in prostate cancer cells.

  BMC biology 20100101

• Regulation of UGT1A1 and HNF1 transcription factor gene expression by DNA methylation in colon cancer cells.

  BMC molecular biology 20100101

• The site specific demethylation in the 5'-regulatory area of NMDA receptor 2B subunit gene associated with CIE-induced up-regulation of transcription.

  PloS one 20100101

• Aberrant gene promoter methylation associated with sporadic multiple colorectal cancer.

  PloS one 20100101

• The behaviour of 5-hydroxymethylcytosine in bisulfite sequencing.

  PloS one 20100101

• CpG methylation of a silent controlling element in the murine Avy allele is incomplete and unresponsive to methyl donor supplementation.

  PloS one 20100101

• Mechanisms of chromosomal rearrangement in the human genome.

  BMC genomics 20100101

• Lsh mediated RNA polymerase II stalling at HoxC6 and HoxC8 involves DNA methylation.

  PloS one 20100101

• Methylation status of individual CpG sites within Alu elements in the human genome and Alu hypomethylation in gastric carcinomas.

  BMC cancer 20100101

• Promoter methylation analysis of O6-methylguanine-DNA methyltransferase in glioblastoma: detection by locked nucleic acid based quantitative PCR using an imprinted gene (SNURF) as a reference.

  BMC cancer 20100101

• DNA cytosine methylation in plant development.

  Journal of genetics and genomics = Yi chuan xue bao 20100101

• Expression of the leukemic prognostic marker CD7 is linked to epigenetic modifications in chronic myeloid leukemia.

  Molecular cancer 20100101

• Whole methylome analysis by ultra-deep sequencing using two-base encoding.

  PloS one 20100101

• Genome-wide analysis of aberrant methylation in human breast cancer cells using methyl-DNA immunoprecipitation combined with high-throughput sequencing.

  BMC genomics 20100101

• A genome-wide screen identifies frequently methylated genes in haematological and epithelial cancers.

  Molecular cancer 20100101

• Influence of genetic background and tissue types on global DNA methylation patterns.

  PloS one 20100101

• Different DNA methylation patterns detected by the Amplified Methylation Polymorphism Polymerase Chain Reaction (AMP PCR) technique among various cell types of bulls.

  Acta veterinaria Scandinavica 20100101

• Regulation of gene expression in protozoa parasites.

  Journal of biomedicine & biotechnology 20100101

• Transgenerational adaptation of Arabidopsis to stress requires DNA methylation and the function of Dicer-like proteins.

  PloS one 20100101

• Genome-wide DNA demethylation in mammals.

  Genome biology 20100101

• DNA methylation as a biomarker for cardiovascular disease risk.

  PloS one 20100101

• Strict de novo methylation of the 35S enhancer sequence in gentian.

  PloS one 20100101

• Circadian rhythm and its role in malignancy.

  Journal of circadian rhythms 20100101

• Replication independent DNA double-strand break retention may prevent genomic instability.

  Molecular cancer 20100101

• Targeting of de novo DNA methylation throughout the Oct-4 gene regulatory region in differentiating embryonic stem cells.

  PloS one 20100101

• A study of the influence of sex on genome wide methylation.

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• BS Seeker: precise mapping for bisulfite sequencing.

  BMC bioinformatics 20100101

• BISMA--fast and accurate bisulfite sequencing data analysis of individual clones from unique and repetitive sequences.

  BMC bioinformatics 20100101

• LINE-1 methylation is inherited in familial testicular cancer kindreds.

  BMC medical genetics 20100101

• Transcription-associated mutagenesis increases protein sequence diversity more effectively than does random mutagenesis in Escherichia coli.

  PloS one 20100101

• Biosynthesis and molecular genetics of polyketides in marine dinoflagellates.

  Marine drugs 20100101

• Investigating the epigenetic effects of a prototype smoke-derived carcinogen in human cells.

  PloS one 20100101

• Extensive sequence-influenced DNA methylation polymorphism in the human genome.

  Epigenetics & chromatin 20100101

• SETDB1 is involved in postembryonic DNA methylation and gene silencing in Drosophila.

  PloS one 20100101

• Epigenomic diversity of colorectal cancer indicated by LINE-1 methylation in a database of 869 tumors.

  Molecular cancer 20100101

• A combined HM-PCR/SNuPE method for high sensitive detection of rare DNA methylation.

  Epigenetics & chromatin 20100101

• Prediction of epigenetically regulated genes in breast cancer cell lines.

  BMC bioinformatics 20100101

• Characteristics of transposable element exonization within human and mouse.

  PloS one 20100101

• Epigenetics of human cutaneous melanoma: setting the stage for new therapeutic strategies.

  Journal of translational medicine 20100101

• High-definition DNA methylation profiles from breast and ovarian carcinoma cell lines with differing doxorubicin resistance.

  PloS one 20100101

• Active loss of DNA methylation in two-cell stage goat embryos.

  The International journal of developmental biology 20100101

• Active DNA demethylation in human postmitotic cells correlates with activating histone modifications, but not transcription levels.

  Genome biology 20100101

• [Peculiarities of 5-methylcytosine distribution in eukaryotic genome].

  Molekuliarnaia biologiia 20100101

• Patterns of nucleotides that flank substitutions in human orthologous genes.

  BMC genomics 20100101

• Disruption of Dnmt1/PCNA/UHRF1 interactions promotes tumorigenesis from human and mice glial cells.

  PloS one 20100101

• Altered intra-nuclear organisation of heterochromatin and genes in ICF syndrome.

  PloS one 20100101

• Detection of fetomaternal genotype associations in early-onset disorders: evaluation of different methods and their application to childhood leukemia.

  Journal of biomedicine & biotechnology 20100101

• Demethylation by 5-aza-2'-deoxycytidine in colorectal cancer cells targets genomic DNA whilst promoter CpG island methylation persists.

  BMC cancer 20100101

• SOX11 expression correlates to promoter methylation and regulates tumor growth in hematopoietic malignancies.

  Molecular cancer 20100101

• Sulforaphane causes epigenetic repression of hTERT expression in human breast cancer cell lines.

  PloS one 20100101

• Oxidative stress and DNA methylation in prostate cancer.

  Obstetrics and gynecology international 20100101

• Methylated APC and GSTP1 genes in serum DNA correlate with the presence of circulating blood tumor cells and are associated with a more aggressive and advanced breast cancer disease.

  European journal of medical research 20100101

• Modelling the ancestral sequence distribution and model frequencies in context-dependent models for primate non-coding sequences.

  BMC evolutionary biology 20100101

• The human proteins MBD5 and MBD6 associate with heterochromatin but they do not bind methylated DNA.

  PloS one 20100101

• Trans-generational epigenetic regulation of C. elegans primordial germ cells.

  Epigenetics & chromatin 20100101

• Repeated reunions and splits feature the highly dynamic evolution of 5S and 35S ribosomal RNA genes (rDNA) in the Asteraceae family.

  BMC plant biology 20100101

• Nitric oxide: perspectives and emerging studies of a well known cytotoxin.

  International journal of molecular sciences 20100101

• DNA-Destabilizing Agents as an Alternative Approach for Targeting DNA: Mechanisms of Action and Cellular Consequences.

  Journal of nucleic acids 20100101

• True lies: the double life of the nucleotide excision repair factors in transcription and DNA repair.

  Journal of nucleic acids 20100101

• Bisulphite sequencing of plant genomic DNA.

  Methods in molecular biology (Clifton, N.J.) 20100101

• Specificity of methylation assays in cancer research: a guideline for designing primers and probes.

  Obstetrics and gynecology international 20100101

• Stimulation of DNA Glycosylase Activities by XPC Protein Complex: Roles of Protein-Protein Interactions.

  Journal of nucleic acids 20100101

• DNA methylation patterns provide insight into epigenetic regulation in the Pacific oyster (Crassostrea gigas).

  BMC genomics 20100101

• A combined epigenetic and non-genetic approach for reprogramming human somatic cells.

  PloS one 20100101

• Epigenetic regulatory mechanisms associated with infertility.

  Obstetrics and gynecology international 20100101

• RNA Genes: Retroelements and Virally Retroposable microRNAs in Human Embryonic Stem Cells.

  The open virology journal 20100101

• Methylation-mediated deamination of 5-methylcytosine appears to give rise to mutations causing human inherited disease in CpNpG trinucleotides, as well as in CpG dinucleotides.

  Human genomics 20100101

• Similar patterns of rDNA evolution in synthetic and recently formed natural populations of Tragopogon (Asteraceae) allotetraploids.

  BMC evolutionary biology 20100101

• Dynamic instability of genomic methylation patterns in pluripotent stem cells.

  Epigenetics & chromatin 20100101

• Genome-wide conserved consensus transcription factor binding motifs are hyper-methylated.

  BMC genomics 20100101

• Genetic and epigenetic characteristics of human multiple hepatocellular carcinoma.

  BMC cancer 20100101

• S110, a novel decitabine dinucleotide, increases fetal hemoglobin levels in baboons (P. anubis).

  Journal of translational medicine 20100101

• Early Steps in the DNA Base Excision Repair Pathway of a Fission Yeast Schizosaccharomyces pombe.

  Journal of nucleic acids 20100101

• Recent advances in diagnosis and treatment of chronic myeloproliferative neoplasms.

  F1000 medicine reports 20100101

• Genomic analysis and relatedness of P2-like phages of the Burkholderia cepacia complex.

  BMC genomics 20100101

• Error-Prone Translesion DNA Synthesis by Escherichia coli DNA Polymerase IV (DinB) on Templates Containing 1,2-dihydro-2-oxoadenine.

  Journal of nucleic acids 20100101

• In vitro tRNA methylation assay with the Entamoeba histolytica DNA and tRNA methyltransferase Dnmt2 (Ehmeth) enzyme.

  Journal of visualized experiments : JoVE 20100101

• Repair of DNA Alkylation Damage by the Escherichia coli Adaptive Response Protein AlkB as Studied by ESI-TOF Mass Spectrometry.

  Journal of nucleic acids 20100101

• The C-terminal domain of the MutL homolog from Neisseria gonorrhoeae forms an inverted homodimer.

  PloS one 20100101

• Gradual transition from mosaic to global DNA methylation patterns during deuterostome evolution.

  BMC bioinformatics 20100101

• Global profiling of histone and DNA methylation reveals epigenetic-based regulation of gene expression during epithelial to mesenchymal transition in prostate cells.

  BMC genomics 20100101

• Inactivation of FBXW7/hCDC4-β expression by promoter hypermethylation is associated with favorable prognosis in primary breast cancer.

  Breast cancer research : BCR 20100101

• Gemcitabine functions epigenetically by inhibiting repair mediated DNA demethylation.

  PloS one 20100101

• Rev1, Rev3, or Rev7 siRNA Abolishes Ultraviolet Light-Induced Translesion Replication in HeLa Cells: A Comprehensive Study Using Alkaline Sucrose Density Gradient Sedimentation.

  Journal of nucleic acids 20100101

• Epigenetic silencing of peroxisome proliferator-activated receptor γ is a biomarker for colorectal cancer progression and adverse patients' outcome.

  PloS one 20100101

• Systematic identification of placental epigenetic signatures for the noninvasive prenatal detection of Edwards syndrome.

  PloS one 20100101

• MethVisual - visualization and exploratory statistical analysis of DNA methylation profiles from bisulfite sequencing.

  BMC research notes 20100101

• Sex- and diet-specific changes of imprinted gene expression and DNA methylation in mouse placenta under a high-fat diet.

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• Tissue distribution of 5-hydroxymethylcytosine and search for active demethylation intermediates.

  PloS one 20100101

• Molecular mechanisms of ultraviolet radiation-induced DNA damage and repair.

  Journal of nucleic acids 20100101

• Formation and repair of tobacco carcinogen-derived bulky DNA adducts.

  Journal of nucleic acids 20100101

• Global DNA methylation in precancerous and cancerous lesions of the uterine cervix.

  Asian Pacific journal of cancer prevention : APJCP 20100101

• Impact of the DNA methyltransferases expression on the methylation status of apoptosis-associated genes in glioblastoma multiforme.

  Cell death & disease 20100101

• DNA methylation and histone modification in onion chromosomes.

  Genes & genetic systems 20100101

• Mitochondrial phylogenies in the light of pseudogenes and Wolbachia: re-assessment of a bark beetle dataset.

  ZooKeys 20100101

• Localization of DNA methyltransferase-1 during oocyte differentiation, in vitro maturation and early embryonic development in cow.

  European journal of histochemistry : EJH 20091229

• Role of two strictly conserved residues in nucleotide flipping and N-glycosylic bond cleavage by human thymine DNA glycosylase.

  The Journal of biological chemistry 20091225

• Cancer gene discovery in mouse and man.

  Biochimica et biophysica acta 20091201

• DNA hypomethylation in rheumatoid arthritis synovial fibroblasts.

  Arthritis and rheumatism 20091201

• The central role of chromatin maintenance in aging.

  Aging 20091201

• Cytosinium-hydrogen maleate-cytosine (1/1/1).

  Acta crystallographica. Section E, Structure reports online 20091201

• DNA hypomethylation induced by tributyltin, triphenyltin, and a mixture of these in Sebastiscus marmoratus liver.

  Aquatic toxicology (Amsterdam, Netherlands) 20091108

• Association between global DNA hypomethylation in leukocytes and risk of breast cancer.

  Carcinogenesis 20091101

• Single-nucleotide and long-patch base excision repair of DNA damage in plants.

  The Plant journal : for cell and molecular biology 20091101

• Np95 interacts with de novo DNA methyltransferases, Dnmt3a and Dnmt3b, and mediates epigenetic silencing of the viral CMV promoter in embryonic stem cells.

  EMBO reports 20091101

• Estimating the integrity of aged DNA samples by CE.

  Electrophoresis 20091101

• The cis-(5R,6S)-thymine glycol lesion occupies the wobble position when mismatched with deoxyguanosine in DNA.

  Biochemistry 20091020

• Repression of induced apoptosis in the 2-cell bovine embryo involves DNA methylation and histone deacetylation.

  Biochemical and biophysical research communications 20091016

• Acceleration of 5-methylcytosine deamination in cyclobutane dimers by G and its implications for UV-induced C-to-T mutation hotspots.

  Journal of molecular biology 20091009

• DNA methylation during depleted uranium-induced leukemia.

  Biochimie 20091001

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  Analytical chemistry 20090901

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  Environmental health perspectives 20090901

• Cytosine methylation effects on the repair of O6-methylguanines within CG dinucleotides.

  The Journal of biological chemistry 20090821

• Prognostic role of global DNA-methylation and histone acetylation in pT1a clear cell renal carcinoma in partial nephrectomy specimens.

  Journal of cellular and molecular medicine 20090801

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  The Plant journal : for cell and molecular biology 20090801

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  Zygote (Cambridge, England) 20090801

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  The Journal of reproduction and development 20090801

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  Journal of mass spectrometry : JMS 20090801

• Comparative methylation of ERVWE1/syncytin-1 and other human endogenous retrovirus LTRs in placenta tissues.

  DNA research : an international journal for rapid publication of reports on genes and genomes 20090801

• CpG methylation controls reactivation of HIV from latency.

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• UHRF1 is a novel molecular marker for diagnosis and the prognosis of bladder cancer.

  British journal of cancer 20090707

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  Molecular genetics and genomics : MGG 20090701

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  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20090701

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  Genome research 20090601

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  Bioelectrochemistry (Amsterdam, Netherlands) 20090601

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  Clinical cancer research : an official journal of the American Association for Cancer Research 20090515

• Substituted imidazopyridines as potent inhibitors of HCV replication.

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  British journal of cancer 20090421

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  Genomics 20090401

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  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090401

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  Organic letters 20090319

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  Methods (San Diego, Calif.) 20090301

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  Current genomics 20090301

• DLEC1 is a functional 3p22.3 tumour suppressor silenced by promoter CpG methylation in colon and gastric cancers.

  British journal of cancer 20090224

• Effects of CpG methylation on recognition of DNA by the tumour suppressor p53.

  Journal of molecular biology 20090213

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  Cellular and molecular life sciences : CMLS 20090201

• DNA demethylation by DNA repair.

  Trends in genetics : TIG 20090201

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  Biochemistry. Biokhimiia 20090201

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  Environmental health perspectives 20090201

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  Neuroreport 20090128

• Survival motor neuron gene 2 silencing by DNA methylation correlates with spinal muscular atrophy disease severity and can be bypassed by histone deacetylase inhibition.

  Human molecular genetics 20090115

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  The EMBO journal 20090107

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  International journal of clinical and experimental pathology 20090101

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  Epigenetics 20090101

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  Medical principles and practice : international journal of the Kuwait University, Health Science Centre 20090101

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  BMC medical genomics 20090101

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• Quantitation of DNA methylation by melt curve analysis.

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  Biochimica et biophysica acta 20090101

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  BMC plant biology 20090101

• High specificity of quantitative methylation-specific PCR analysis for MGMT promoter hypermethylation detection in gliomas.

  Journal of biomedicine & biotechnology 20090101

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  PloS one 20090101

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  Biological procedures online 20090101

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  Methods in molecular biology (Clifton, N.J.) 20090101

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  BMC plant biology 20090101

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  BMC neuroscience 20090101

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  Annual review of genetics 20090101

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  Cell transplantation 20090101

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  PloS one 20090101

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  BMC medical genetics 20090101

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  Genome biology 20090101

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  Particle and fibre toxicology 20090101

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  Nucleic acids symposium series (2004) 20090101

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  PloS one 20090101

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  BMC evolutionary biology 20090101

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  Journal of biomedicine & biotechnology 20090101

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  PloS one 20090101

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  Genome medicine 20090101

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  BMC cancer 20090101

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  Neural plasticity 20090101

• Protein modifications as potential biomarkers in breast cancer.

  Biomarker insights 20090101

• The importance of epigenetic alterations in the development of epstein-barr virus-related lymphomas.

  Mediterranean journal of hematology and infectious diseases 20090101

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  Cell 20081226

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  Chemical communications (Cambridge, England) 20081207

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  The Plant journal : for cell and molecular biology 20081201

• Unstable RNAi effects through epigenetic silencing of an inverted repeat transgene in Chlamydomonas reinhardtii.

  Genetics 20081201

• Spt2p defines a new transcription-dependent gross chromosomal rearrangement pathway.

  PLoS genetics 20081201

• Physcomitrella patens DCL3 is required for 22-24 nt siRNA accumulation, suppression of retrotransposon-derived transcripts, and normal development.

  PLoS genetics 20081201

• Chromosomal losses are associated with hypomethylation of the gene-control regions in the stomach with a low number of active genes.

  Journal of Korean medical science 20081201

• Crystal structure of the Escherichia coli 23S rRNA:m5C methyltransferase RlmI (YccW) reveals evolutionary links between RNA modification enzymes.

  Journal of molecular biology 20081114

• Cloning, purification and initial characterization of E. coli McrA, a putative 5-methylcytosine-specific nuclease.

  Protein expression and purification 20081101

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  Eukaryotic cell 20081101

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  Histochemistry and cell biology 20081101

• Global DNA hypomethylation is associated with high serum-persistent organic pollutants in Greenlandic Inuit.

  Environmental health perspectives 20081101

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  Nature 20081030

• MeCP2 expression and promoter methylation of cyclin D1 gene are associated with cyclin D1 expression in developing rat epididymal duct.

  Acta histochemica et cytochemica 20081029

• C-Fos expression is a molecular predictor of progression and survival in epithelial ovarian carcinoma.

  British journal of cancer 20081021

• The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix.

  Nature 20081009

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  Nature 20081009

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  Nature 20081009

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  Critical reviews in oncology/hematology 20081001

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  Analytical and bioanalytical chemistry 20081001

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  Systematic biology 20081001

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  Biochemistry and cell biology = Biochimie et biologie cellulaire 20081001

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  Proceedings of the Japan Academy. Series B, Physical and biological sciences 20081001

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  Journal of the American Chemical Society 20080903

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  Human molecular genetics 20080901

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  Epigenetics 20080901

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  Genomics 20080801

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  Genomics 20080701

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  Cancer research 20080615

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  Journal of chromatography. A 20080606

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  Journal of molecular biology 20080606

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  Cancer metastasis reviews 20080601

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  Reproduction (Cambridge, England) 20080601

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  Current protocols in nucleic acid chemistry 20080601

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• Expression of methylation-related genes is associated with overall survival in patients with non-small cell lung cancer.

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• The methylome: approaches for global DNA methylation profiling.

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  Journal of mass spectrometry : JMS 20080401

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  Genome research 20080401

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  International journal of molecular sciences 20080401

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  Nature 20080313

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  BMC biotechnology 20080101

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  Mutation research 20080101

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  BMC medical genomics 20080101

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  Molecular cancer 20080101

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  Protoplasma 20080101

• Optical mapping discerns genome wide DNA methylation profiles.

  BMC molecular biology 20080101

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  BMC cancer 20080101

• In vitro analysis of integrated global high-resolution DNA methylation profiling with genomic imbalance and gene expression in osteosarcoma.

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  BMC cancer 20080101

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  BMC research notes 20080101

• Reduced-representation methylation mapping.

  Genome biology 20080101

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  Nucleic acids symposium series (2004) 20080101

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  Nucleic acids symposium series (2004) 20080101

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  BMC cancer 20080101

• Kismeth: analyzer of plant methylation states through bisulfite sequencing.

  BMC bioinformatics 20080101

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  BMC physiology 20080101

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  Chemistry (Weinheim an der Bergstrasse, Germany) 20080101

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  International journal of immunopathology and pharmacology 20080101

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  Genome biology 20080101

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  Genome biology 20080101

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  Biological procedures online 20080101

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  Biology direct 20080101

• DNA methylation and mRNA expression of SYN III, a candidate gene for schizophrenia.

  BMC medical genetics 20080101

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  Molecular cancer 20080101

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  The open medicinal chemistry journal 20080101

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  Gene regulation and systems biology 20080101

• Epigenetics, behaviour, and health.

  Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology 20080101

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• Genetic and epigenetic changes in the common 1p36 deletion in neuroblastoma tumours.

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• Mutagenicity of the 1-nitropyrene-DNA adduct N-(deoxyguanosin-8-yl)-1-aminopyrene in mammalian cells.

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  Molecular reproduction and development 20071001

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  Cancer research 20071001

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  The journal of physical chemistry. A 20070920

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• DNA damage, homology-directed repair, and DNA methylation.

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  Experimental and molecular pathology 20070601

• Direct labeling of 5-methylcytosine and its applications.

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• Abiotic-stress induces demethylation and transcriptional activation of a gene encoding a glycerophosphodiesterase-like protein in tobacco plants.

  Molecular genetics and genomics : MGG 20070501

• Predicting gene promoter methylation in non-small-cell lung cancer by evaluating sputum and serum.

  British journal of cancer 20070423

• Covalent genomic DNA modification patterns revealed by denaturing gradient gel blots.

  Gene 20070415

• Specific hypermethylation of LINE-1 elements during abnormal overgrowth and differentiation of human placenta.

  Oncogene 20070412

• The enigmatic thymine DNA glycosylase.

  DNA repair 20070401

• Aberrant epigenetic modifications in hepatocarcinogenesis induced by hepatitis B virus X protein.

  Gastroenterology 20070401

• Retrotransposon silencing by DNA methylation can drive mammalian genomic imprinting.

  PLoS genetics 20070401

• Use of DNA methylation for cancer detection and molecular classification.

  Journal of biochemistry and molecular biology 20070331

• FXYD1 is an MeCP2 target gene overexpressed in the brains of Rett syndrome patients and Mecp2-null mice.

  Human molecular genetics 20070315

• Effects of combinations of Fusarium mycotoxins on the inhibition of macromolecular synthesis, malondialdehyde levels, DNA methylation and fragmentation, and viability in Caco-2 cells.

  Toxicon : official journal of the International Society on Toxinology 20070301

• Single-molecule and population probing of chromatin structure using DNA methyltransferases.

  Methods (San Diego, Calif.) 20070301

• A type IV modification dependent restriction nuclease that targets glucosylated hydroxymethyl cytosine modified DNAs.

  Journal of molecular biology 20070223

• Exclusion of glucosyl-hydroxymethylcytosine DNA containing bacteriophages is overcome by the injected protein inhibitor IPI*.

  Journal of molecular biology 20070223

• Simultaneous detection of purine and pyrimidine at highly boron-doped diamond electrodes by using liquid chromatography.

  Talanta 20070215

• The role of citrullinated proteins suggests a novel mechanism in the pathogenesis of multiple sclerosis.

  Neurochemical research 20070201

• Endogenous cytosine damage products alter the site selectivity of human DNA maintenance methyltransferase DNMT1.

  Cancer research 20070201

• Genomic DNA methylation patterns in bovine preimplantation embryos derived from in vitro fertilization.

  Science in China. Series C, Life sciences 20070201

• Frequent reduced expression of alpha-1B-adrenergic receptor caused by aberrant promoter methylation in gastric cancers.

  British journal of cancer 20070129

• Identification and analysis of single nucleotide polymorphisms (SNPs) in the mosquito Anopheles funestus, malaria vector.

  BMC genomics 20070101

• Growth of the protozoan parasite Entamoeba histolytica in 5-azacytidine has limited effects on parasite gene expression.

  BMC genomics 20070101

• FRA-1 protein overexpression is a feature of hyperplastic and neoplastic breast disorders.

  BMC cancer 20070101

• Evolution of motif variants and positional bias of the cyclic-AMP response element.

  BMC evolutionary biology 20070101

• 5-methylcytosine--the fifth base of DNA: the fifth wheel on a car or a highly promising diagnostic and therapeutic target in cancer?

  Disease markers 20070101

• Sp1/Sp3 and DNA-methylation contribute to basal transcriptional activation of human podoplanin in MG63 versus Saos-2 osteoblastic cells.

  BMC molecular biology 20070101

• The expression of mismatched repair genes and their correlation with clinicopathological parameters and response to neo-adjuvant chemotherapy in breast cancer.

  International seminars in surgical oncology : ISSO 20070101

• Methyl-CpG-binding domain (MBD) proteins in plants.

  Biochimica et biophysica acta 20070101

• [DNA of some regions of constitutive heterochromatin is demethylated and decondensed in MRC5 and A431 cells].

  Tsitologiia 20070101

• CGKB: an annotation knowledge base for cowpea (Vigna unguiculata L.) methylation filtered genomic genespace sequences.

  BMC bioinformatics 20070101

• LINE-1 hypomethylation in cancer is highly variable and inversely correlated with microsatellite instability.

  PloS one 20070101

• Analysis of the features and source gene composition of the AluYg6 subfamily of human retrotransposons.

  BMC evolutionary biology 20070101

• Global DNA methylation measured by liquid chromatography-tandem mass spectrometry: analytical technique, reference values and determinants in healthy subjects.

  Clinical chemistry and laboratory medicine 20070101

• Identification of modified residues in RNAs by reverse transcription-based methods.

  Methods in enzymology 20070101

• Methylation-sensitive single-nucleotide primer extension (Ms-SNuPE) for quantitative measurement of DNA methylation.

  Nature protocols 20070101

• A gammaherpesviral internal repeat contributes to latency amplification.

  PloS one 20070101

• Functional diversification of the nematode mbd2/3 gene between Pristionchus pacificus and Caenorhabditis elegans.

  BMC genetics 20070101

• The effect of body weight on altered expression of nuclear receptors and cyclooxygenase-2 in human colorectal cancers.

  Nutrition journal 20070101

• Transcriptional regulation at a glance.

  BMC bioinformatics 20070101

• Induction of DNA hypomethylation by tumor hypoxia.

  Epigenetics 20070101

• Postembryonic establishment of megabase-scale gene silencing in nucleolar dominance.

  PloS one 20070101

• DNA methylation analysis using metal complex formation.

  Nucleic acids symposium series (2004) 20070101

• Chemistry of bisulfite genomic sequencing; advances and issues.

  Nucleic acids symposium series (2004) 20070101

• Site-selective strand cleavage at methylated cytosine: regional effect of naphthoquinone chromophore on the one-electron photooxidation of 5-methylcytosine and positive charge transfer in DNA.

  Nucleic acids symposium series (2004) 20070101

• Photochemical transition of 5-methylcytosine to thymine by DNA photoligation.

  Nucleic acids symposium series (2004) 20070101

• Selective oxidation of methylcytosine in single base pair mismatches by osmium complex.

  Nucleic acids symposium series (2004) 20070101

• Putative zinc finger protein binding sites are over-represented in the boundaries of methylation-resistant CpG islands in the human genome.

  PloS one 20070101

• Tissue factor pathway inhibitor-2 was repressed by CpG hypermethylation through inhibition of KLF6 binding in highly invasive breast cancer cells.

  BMC molecular biology 20070101

• 5-methylcytosine-selective osmium oxidation.

  Nucleosides, nucleotides & nucleic acids 20070101

• Methylation-dependent fragment separation: novel analysis of 5-methyl cytosine by capillary electrophoresis of amplified DNA using PCR incorporation of chemically modified dCTP.

  Nucleosides, nucleotides & nucleic acids 20070101

• Identification of novel high-frequency DNA methylation changes in breast cancer.

  PloS one 20070101

• [The evaluation of level of epigenetic indicator--5-methylcytosine in smoking and non-smoking patients with mild essential hypertension].

  Przeglad lekarski 20070101

• DNA methylation in circulating tumour DNA as a biomarker for cancer.

  Biomarker insights 20070101

• LC/ESI-MS demonstrates the absence of 5-methyl-2'-deoxycytosine in Plasmodium falciparum genomic DNA.

  Molecular and biochemical parasitology 20061201

• Interaction between methyl CpG-binding protein and ran GTPase during cell division in tobacco cultured cells.

  Annals of botany 20061201

• Toward a human epigenome.

  Nature genetics 20061201

• Assembly of protein-RNA complexes using natural RNA and mutant forms of an RNA cytosine methyltransferase.

  Biomacromolecules 20061201

• Rapid and quantitative method of allele-specific DNA methylation analysis.

  BioTechniques 20061201

• Azacytidine (Vidaza(R)) in the treatment of myelodysplastic syndromes.

  Therapeutics and clinical risk management 20061201

• DNA methylation during mouse hemopoietic differentiation and radiation-induced leukemia.

  Experimental hematology 20061101

• Interleukin-6 contributes to growth in cholangiocarcinoma cells by aberrant promoter methylation and gene expression.

  Cancer research 20061101

• Cloning of Nt.CviQII nicking endonuclease and its cognate methyltransferase: M.CviQII methylates AG sequences.

  Protein expression and purification 20060901

• DNA methylation of fly genes and transposons.

  Cellular and molecular life sciences : CMLS 20060901

• Genome-wide hypomethylation in human glioblastomas associated with specific copy number alteration, methylenetetrahydrofolate reductase allele status, and increased proliferation.

  Cancer research 20060901

• [DNA sperm methylation in assisted reproductive techniques].

  Gynecologie, obstetrique & fertilite 20060901

• Key issues in the modes of action and effects of trichloroethylene metabolites for liver and kidney tumorigenesis.

  Environmental health perspectives 20060901

• Constitutive nucleosome depletion and ordered factor assembly at the GRP78 promoter revealed by single molecule footprinting.

  PLoS genetics 20060901

• [DNA methylation and epigenetics].

  Genetika 20060901

• Glu346Lys polymorphism in the methyl-CpG binding domain 4 gene and the risk of primary lung cancer.

  Japanese journal of clinical oncology 20060801

• The DNA N-glycosylase MED1 exhibits preference for halogenated pyrimidines and is involved in the cytotoxicity of 5-iododeoxyuridine.

  Cancer research 20060801

• Methylation-dependent fragment separation: direct detection of DNA methylation by capillary electrophoresis of PCR products from bisulfite-converted genomic DNA.

  Analytical biochemistry 20060715

• Tissue-specific effects of in vitro fertilization procedures on genomic cytosine methylation levels in overgrown and normal sized bovine fetuses.

  Biology of reproduction 20060701

• Existence of a no effect level for MeIQx hepatocarcinogenicity on a background of thioacetamide-induced liver damage in rats.

  Cancer science 20060601

• Arabidopsis displays centromeric DNA hypomethylation and cytological alterations of heterochromatin upon attack by pseudomonas syringae.

  Molecular plant-microbe interactions : MPMI 20060601

• Undetectable levels of N6-methyl adenine in mouse DNA: Cloning and analysis of PRED28, a gene coding for a putative mammalian DNA adenine methyltransferase.

  FEBS letters 20060529

• Sequence-selective osmium oxidation of DNA: efficient distinction between 5-methylcytosine and cytosine.

  Organic & biomolecular chemistry 20060507

• Repair of thymine glycol by hNth1 and hNeil1 is modulated by base pairing and cis-trans epimerization.

  DNA repair 20060408

• Survey of air pollution in Cotonou, Benin--air monitoring and biomarkers.

  The Science of the total environment 20060401

• DNA methylation is critical for Arabidopsis embryogenesis and seed viability.

  The Plant cell 20060401

• Transposon-derived repeats in the human genome and 5-methylcytosine-associated mutations in adjacent genes.

  Gene 20060329

• N6-methyladenine: the other methylated base of DNA.

  BioEssays : news and reviews in molecular, cellular and developmental biology 20060301

• Meiotically stable natural epialleles of Sadhu, a novel Arabidopsis retroposon.

  PLoS genetics 20060301

• Promoter methylation of P16, RARbeta, E-cadherin, cyclin A1 and cytoglobin in oral cancer: quantitative evaluation using pyrosequencing.

  British journal of cancer 20060227

• Ultra-sensitive immunodetection of 5'methyl cytosine for DNA methylation analysis on oligonucleotide microarrays.

  DNA research : an international journal for rapid publication of reports on genes and genomes 20060227

• DEMETER DNA glycosylase establishes MEDEA polycomb gene self-imprinting by allele-specific demethylation.

  Cell 20060210

• Characterization of high molecular weight impurities in synthetic phosphorothioate oligonucleotides.

  Bioorganic & medicinal chemistry letters 20060201

• Assessing the fidelity of ancient DNA sequences amplified from nuclear genes.

  Genetics 20060201

• Epigenetics provides a new generation of oncogenes and tumour-suppressor genes.

  British journal of cancer 20060130

• Developmentally regulated DNA methylation in Dictyostelium discoideum.

  Eukaryotic cell 20060101

• Hydralazine target: from blood vessels to the epigenome.

  Journal of translational medicine 20060101

• CDH1 promoter hypermethylation and E-cadherin protein expression in infiltrating breast cancer.

  BMC cancer 20060101

• Epigenetic regulation: DNA confers identity but is not enough to maintain it.

  Genome biology 20060101

• Replication and translation of epigenetic information.

  Current topics in microbiology and immunology 20060101

• DNA methylation in plants.

  Current topics in microbiology and immunology 20060101

• Mutagenesis at methylated CpG sequences.

  Current topics in microbiology and immunology 20060101

• Cytosine methylation and DNA repair.

  Current topics in microbiology and immunology 20060101

• Immunodeficiency, centromeric region instability, facial anomalies syndrome (ICF).

  Orphanet journal of rare diseases 20060101

• Using immunofluorescence to observe methylation changes in mammalian preimplantation embryos.

  Methods in molecular biology (Clifton, N.J.) 20060101

• Impact of hormonal therapy on the detection of promoter hypermethylation of the detoxifying glutathione-S-transferase P1 gene (GSTP1) in prostate cancer.

  BMC urology 20060101

• Abnormal X: autosome ratio, but normal X chromosome inactivation in human triploid cultures.

  BMC genetics 20060101

• Methylation mediated silencing of TMS1/ASC gene in prostate cancer.

  Molecular cancer 20060101

• LINE-1 hypomethylation in a choline-deficiency-induced liver cancer in rats: dependence on feeding period.

  Journal of biomedicine & biotechnology 20060101

• Global DNA hypermethylation-associated cancer chemotherapy resistance and its reversion with the demethylating agent hydralazine.

  Journal of translational medicine 20060101

• Cancer-linked DNA hypomethylation and its relationship to hypermethylation.

  Current topics in microbiology and immunology 20060101

• The BiSearch web server.

  BMC bioinformatics 20060101

• Association of MTHFR gene polymorphisms with breast cancer survival.

  BMC cancer 20060101

• methBLAST and methPrimerDB: web-tools for PCR based methylation analysis.

  BMC bioinformatics 20060101

• Non coding RNA and brain.

  BMC neuroscience 20060101

• A baboon model for endometriosis: implications for fertility.

  Reproductive biology and endocrinology : RB&E 20060101

• Haloperidol treatment induces tissue- and sex-specific changes in DNA methylation: a control study using rats.

  Behavioral and brain functions : BBF 20060101

• Synthesis of deoxycytidine derivatives and their use for the selective photo crosslinking with 5-methylcytosine.

  Nucleic acids symposium series (2004) 20060101

• Does urea promote the bisulfite-mediated deamination of cytosine in DNA? Investigation aiming at speeding-up the procedure for DNA methylation analysis.

  Nucleic acids symposium series (2004) 20060101

• Development of bipyridine-modified nucleobase for methylcytosine-selective crosslink reaction.

  Nucleic acids symposium series (2004) 20060101

• Development of fluorescence-labeling method for methylcytosine with metal complexation.

  Nucleic acids symposium series (2004) 20060101

• Fluorescence quenching by methylcytosine-metal complexation.

  Nucleic acids symposium series (2004) 20060101

• Development of electrochemical detection for methylcytosine and its application.

  Nucleic acids symposium series (2004) 20060101

• Sensitive discrimination between cytosine and 5-methylcytosine in DNA by a modified invader method.

  Nucleic acids symposium series (2004) 20060101

• Directionality of point mutation and 5-methylcytosine deamination rates in the chimpanzee genome.

  BMC genomics 20060101

• A proof-of-principle study of epigenetic therapy added to neoadjuvant doxorubicin cyclophosphamide for locally advanced breast cancer.

  PloS one 20060101

• A novel statistical method to estimate the effective SNP size in vertebrate genomes and categorized genomic regions.

  BMC genomics 20060101

• Mandatory fortification with folic acid in the United States is not associated with changes in the degree or the pattern of global DNA methylation in cells involved in cervical carcinogenesis.

  Cancer biomarkers : section A of Disease markers 20060101

• Quantification of DNA methylation in electrofluidics chips (Bio-COBRA).

  Nature protocols 20060101

• DNA methylation: bisulphite modification and analysis.

  Nature protocols 20060101

• Epigenetics: a historical overview.

  Epigenetics 20060101

• Methylation changes of lysine 9 of histone H3 during preimplantation mouse development.

  Molecules and cells 20051231

• Pattern of nonspecific (or global) DNA methylation in oral carcinogenesis.

  Head & neck 20051201

• 5-Azacytidine decreases fragmentation of nuclear DNA and pigment formation in first leaf cells of barley seedlings.

  Cell biology international 20051201

• Differential regulation of strand-specific transcripts from Arabidopsis centromeric satellite repeats.

  PLoS genetics 20051201

• DNA methylation impacts the cleavage activity of Chlorella virus topoisomerase II.

  Biochemistry 20051122

• Epigenetic and classical activation of Entamoeba histolytica heat shock protein 100 (EHsp100) expression.

  FEBS letters 20051121

• Both hypomethylation and hypermethylation in a 0.2-kb region of a DNA repeat in cancer.

  Molecular cancer research : MCR 20051101

• Non-CpG-containing antisense 2'-methoxyethyl oligonucleotides activate a proinflammatory response independent of Toll-like receptor 9 or myeloid differentiation factor 88.

  The Journal of pharmacology and experimental therapeutics 20050901

• DNA methylating and demethylating treatments modify phenotype and cell wall differentiation state in sugarbeet cell lines.

  Plant physiology and biochemistry : PPB 20050701

• Towards an understanding of DNA recognition by the methyl-CpG binding domain 1.

  Journal of biomolecular structure & dynamics 20050601

• Chromatin remodeling in plant cell culture: patterns of DNA methylation and histone H3 and H4 acetylation vary during growth of asynchronous potato cell suspensions.

  Plant physiology and biochemistry : PPB 20050601

• Capillary electrophoresis-laser induced fluorescence analysis of endogenous damage in mitochondrial and genomic DNA.

  Electrophoresis 20050601

• Methyl-CpG-binding proteins in cancer: blaming the DNA methylation messenger.

  Biochemistry and cell biology = Biochimie et biologie cellulaire 20050601

• Environmental programming of stress responses through DNA methylation: life at the interface between a dynamic environment and a fixed genome.

  Dialogues in clinical neuroscience 20050601

• Increased protein stability causes DNA methyltransferase 1 dysregulation in breast cancer.

  The Journal of biological chemistry 20050506

• Enzymatic DNA methylation is an epigenetic control for genetic functions of the cell.

  Biochemistry. Biokhimiia 20050501

• The language of methylation in genomics of eukaryotes.

  Biochemistry. Biokhimiia 20050501

• Mutations induced by ultraviolet light.

  Mutation research 20050401

• Promoter methylation of E-cadherin in hepatocellular carcinomas and dysplastic nodules.

  Journal of Korean medical science 20050401

• Immunodetection of 5'-methylcytosine on Giemsa-stained chromosomes.

  BioTechniques 20050401

• CpG mutation rates in the human genome are highly dependent on local GC content.

  Molecular biology and evolution 20050301

• Influence of global sperm DNA methylation on IVF results.

  Human reproduction (Oxford, England) 20050301

• DNA methylation patterns in human tripronucleate zygotes.

  Molecular human reproduction 20050301

• Determination of 5-methyl-cytosine and cytosine in tumor DNA of cancer patients.

  Electrophoresis 20050301

• Genetic pathways to glioblastomas.

  Neuropathology : official journal of the Japanese Society of Neuropathology 20050301

• Deregulation of DNA methyltransferases and loss of parental methylation at the insulin-like growth factor II (Igf2)/H19 loci in p53 knockout mice prior to tumor development.

  Journal of cellular biochemistry 20050215

• Stable isotope labeling-mass spectrometry analysis of methyl- and pyridyloxobutyl-guanine adducts of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in p53-derived DNA sequences.

  Biochemistry 20050215

• Cleavage at 5-methylcytosine in DNA by photosensitized oxidation with 2-methyl-1,4-naphthoquinone tethered oligodeoxynucleotides.

  Bioorganic & medicinal chemistry letters 20050201

• [Applications of DNA methylation markers in forensic medicine].

  Fa yi xue za zhi 20050201

• DNA methylation profiling identifies CG methylation clusters in Arabidopsis genes.

  Current biology : CB 20050126

• Differential DNA hypermethylation and hypomethylation signatures in colorectal cancer.

  Human molecular genetics 20050115

• Measurement of DNA methylation using stable isotope dilution and gas chromatography-mass spectrometry.

  Analytical biochemistry 20050115

• The N6-methyl group of adenine further increases the BI stability of DNA compared to C5-methyl groups.

  The journal of physical chemistry. B 20050113

• The photochemistry of thymidylyl-(3'-5')-5-methyl-2'-deoxycytidine in aqueous solution.

  Photochemistry and photobiology 20050101

• Global hypomethylation is common in prostate cancer cells: a quantitative predictor for clinical outcome?

  Cancer genetics and cytogenetics 20050101

• Sorghum genome sequencing by methylation filtration.

  PLoS biology 20050101

• Epidemiology and etiology of gliomas.

  Acta neuropathologica 20050101

• Analysis of the human Alu Ye lineage.

  BMC evolutionary biology 20050101

• A cluster of genes located in 1p36 are down-regulated in neuroblastomas with poor prognosis, but not due to CpG island methylation.

  Molecular cancer 20050101

• Aberrant DNA methylation as a cancer-inducing mechanism.

  Annual review of pharmacology and toxicology 20050101

• A phase I study of hydralazine to demethylate and reactivate the expression of tumor suppressor genes.

  BMC cancer 20050101

• Molecular breakpoint cloning and gene expression studies of a novel translocation t(4;15)(q27;q11.2) associated with Prader-Willi syndrome.

  BMC medical genetics 20050101

• A transcriptome map of cellular transformation by the fos oncogene.

  Molecular cancer 20050101

• Data-mining analysis suggests an epigenetic pathogenesis for type 2 diabetes.

  Journal of biomedicine & biotechnology 20050101

• Epigenetic silencing of DSC3 is a common event in human breast cancer.

  Breast cancer research : BCR 20050101

• Tracking Alu evolution in New World primates.

  BMC evolutionary biology 20050101

• The diagnosis and therapy of brain tumours.

  Folia neuropathologica 20050101

• Epigenetics of cervical cancer. An overview and therapeutic perspectives.

  Molecular cancer 20050101

• Expression, purification and characterization of methyl DNA binding protein from Bombyx mori.

  Journal of insect science (Online) 20050101

• The role of mammalian DNA methyltransferases in the regulation of gene expression.

  Cellular & molecular biology letters 20050101

• [Changes in composition of acid soluble proteins and DNA in chromatin of rat liver and brain bound and not bound to nuclear envelope as a function of age and under the influence of antioxidant ionol].

  Ontogenez 20050101

• DNA methylation patterns in in vitro-fertilised goat zygotes.

  Reproduction, fertility, and development 20050101

• [Peculiarities of metaphase chromosome methylation pattern in preimplantation human embryos].

  Tsitologiia 20050101

• [Immunocytochemical analysis of human metaphase chromosome methylation status].

  Tsitologiia 20050101

• Sequence-selective 5-methylcytosine oxidation for epigenotyping.

  Nucleic acids symposium series (2004) 20050101

• Detection of 5-methylcytosine in DNA by photo-functionalized oligodeoxynucleotides possessing 2-methyl-1,4-naphthoquinone chromophore.

  Nucleic acids symposium series (2004) 20050101

• High-speed conversion of cytosine to uracil in bisulfite genomic sequencing analysis of DNA methylation.

  DNA research : an international journal for rapid publication of reports on genes and genomes 20041231

• DNA damage and mutations produced by chloroacetaldehyde in a CpG-methylated target gene.

  Mutation research 20041221

• Mutagenic potential of benzo[a]pyrene-derived DNA adducts positioned in codon 273 of the human P53 gene.

  Biochemistry 20041221

• Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: implications for epigenetic reprogramming.

  The Journal of biological chemistry 20041210

• Effect of dibromoacetic acid on DNA methylation, glycogen accumulation, and peroxisome proliferation in mouse and rat liver.

  Toxicological sciences : an official journal of the Society of Toxicology 20041101

• Hypermethylation of the p16 gene in normal oral mucosa of smokers.

  International journal of molecular medicine 20041101

• Identification of a genomic fragment that directs hematopoietic-specific expression of Rac2 and analysis of the DNA methylation profile of the gene locus.

  Gene 20041027

• Maternal chromatin remodeling during maturation and after fertilization in mouse oocytes.

  Molecular reproduction and development 20041001

• The cyclobutane dimers of 5-methylcytosine and their deamination products.

  Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20041001

• Identification of methylated sequences in genomic DNA of adult Drosophila melanogaster.

  Biochemical and biophysical research communications 20040917

• Chronic inorganic arsenic exposure induces hepatic global and individual gene hypomethylation: implications for arsenic hepatocarcinogenesis.

  Carcinogenesis 20040901

• Modeling the impact of DNA methylation on the evolution of BRCA1 in mammals.

  Molecular biology and evolution 20040901

• DNA-methylation alterations and exchanges during in vitro cellular differentiation in rose (Rosa hybrida L.).

  TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik 20040901

• DNA hypomethylation induced by non-genotoxic carcinogens in mouse and rat colon.

  Cancer letters 20040830

• Papillary carcinoma of the thyroid: methylation is not involved in the regulation of MET expression.

  British journal of cancer 20040816

• The relationship between aberrant methylation and survival in non-small-cell lung cancers.

  British journal of cancer 20040816

• A mouse skin multistage carcinogenesis model reflects the aberrant DNA methylation patterns of human tumors.

  Cancer research 20040815

• Structural evidence of a passive base-flipping mechanism for beta-glucosyltransferase.

  The Journal of biological chemistry 20040813

• DNA methylation polymorphisms precede any histological sign of atherosclerosis in mice lacking apolipoprotein E.

  The Journal of biological chemistry 20040709

• Methylation in the core-promoter region of the chondromodulin-I gene determines the cell-specific expression by regulating the binding of transcriptional activator Sp3.

  The Journal of biological chemistry 20040702

• Effect of limited DNA methylation reprogramming in the normal sheep embryo on somatic cell nuclear transfer.

  Biology of reproduction 20040701

• Methylation reprogramming and chromosomal aneuploidy in in vivo fertilized and cloned rabbit preimplantation embryos.

  Biology of reproduction 20040701

• Tissue-specific elevated genomic cytosine methylation levels are associated with an overgrowth phenotype of bovine fetuses derived by in vitro techniques.

  Biology of reproduction 20040701

• One-electron oxidation of DNA: the effect of replacement of cytosine with 5-methylcytosine on long-distance radical cation transport and reaction.

  Journal of the American Chemical Society 20040616

• Formation of diastereomeric benzo[a]pyrene diol epoxide-guanine adducts in p53 gene-derived DNA sequences.

  Chemical research in toxicology 20040601

• Cytosine methylation and CpG, TpG (CpA) and TpA frequencies.

  Gene 20040526

• DNA binding of methyl-CpG-binding protein MeCP2 in human MCF7 cells.

  Biochemistry 20040504

• Methyl-CpG-binding domain 2: a protective role in bladder carcinoma.

  Cancer 20040501

• Effects of budesonide on overall 5-methylcytosine levels and specific methylation and messenger RNA expression of the insulin-like growth factor II gene in mouse lung tumors.

  Chest 20040501

• Age related changes in 5-methylcytosine content in human peripheral leukocytes and placentas: an HPLC-based study.

  Annals of human genetics 20040501

• Preparation and antiviral properties of new acyclic, achiral nucleoside analogues: 1- or 9-[3-hydroxy-2-(hydroxymethyl)prop-1-enyl]nucleobases and 1- or 9-[2,3-dihydroxy-2-(hydroxymethyl)propyl]nucleobases.

  Organic & biomolecular chemistry 20040421

• Methylation analysis of the glypican 3 gene in embryonal tumours.

  British journal of cancer 20040419

• DNA methylation in insects.

  Insect molecular biology 20040401

• Arsenic-induced DNA hypomethylation affects chromosomal instability in mammalian cells.

  Carcinogenesis 20040301

• Hypomethylation of DNA and the insulin-like growth factor-II gene in dichloroacetic and trichloroacetic acid-promoted mouse liver tumors.

  Toxicology 20040301

• A simple epigenetic method for the diagnosis and classification of brain tumors.

  Molecular cancer research : MCR 20040301

• Genetic and DNA-methylation changes induced by potassium dichromate in Brassica napus L.

  Chemosphere 20040201

• Modulation of DNA hypomethylation as a surrogate endpoint biomarker for chemoprevention of colon cancer.

  Molecular carcinogenesis 20040201

• Endogenous 5-methylcytosine protects neighboring guanines from N7 and O6-methylation and O6-pyridyloxobutylation by the tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.

  Biochemistry 20040120

• Frequent hypomethylation in multiple promoter CpG islands is associated with global hypomethylation, but not with frequent promoter hypermethylation.

  Cancer science 20040101

• Synthesis of D-altritol nucleosides with a 3'-O-tert-butyldimethylsilyl protecting group.

  Nucleosides, nucleotides & nucleic acids 20040101

• Evaluation of DNA methylation in the human genome: why examine it and what method to use.

  European journal of gynaecological oncology 20040101

• Epigenetic CRBP downregulation appears to be an evolutionarily conserved (human and mouse) and oncogene-specific phenomenon in breast cancer.

  Molecular cancer 20040101

• Role of promoter hypermethylation in Cisplatin treatment response of male germ cell tumors.

  Molecular cancer 20040101

• Nitric oxide and p53 in cancer-prone chronic inflammation and oxyradical overload disease.

  Environmental and molecular mutagenesis 20040101

• Methylation-specific oligonucleotide microarray.

  Methods in molecular biology (Clifton, N.J.) 20040101

• Aberrant CBFA2T3B gene promoter methylation in breast tumors.

  Molecular cancer 20040101

• A CpG island hypermethylation profile of primary colorectal carcinomas and colon cancer cell lines.

  Molecular cancer 20040101

• Accelerated bisulfite-deamination of cytosine in the genomic sequencing procedure for DNA methylation analysis.

  Nucleic acids symposium series (2004) 20040101

• Gene expression array profile of human osteosarcoma.

  British journal of cancer 20031215

• C5-methylation of cytosine in B-DNA thermodynamically and kinetically stabilizes BI.

  Journal of the American Chemical Society 20031210

• Methyl-CpG binding proteins identify novel sites of epigenetic inactivation in human cancer.

  The EMBO journal 20031201

• The first structure of an RNA m5C methyltransferase, Fmu, provides insight into catalytic mechanism and specific binding of RNA substrate.

  Structure (London, England : 1993) 20031201

• MeCP2 and MBD2 expression in human neoplastic and non-neoplastic breast tissue and its association with oestrogen receptor status.

  British journal of cancer 20031117

• A Dnmt2-like protein mediates DNA methylation in Drosophila.

  Development (Cambridge, England) 20031101

• Exceptionally high protection of photocarcinogenesis by topical application of (--)-epigallocatechin-3-gallate in hydrophilic cream in SKH-1 hairless mouse model: relationship to inhibition of UVB-induced global DNA hypomethylation.

  Neoplasia (New York, N.Y.) 20031101

• Independent generation of 5-(2'-deoxycytidinyl)methyl radical and the formation of a novel cross-link lesion between 5-methylcytosine and guanine.

  Journal of the American Chemical Society 20031022

• DNA sequence recognition by bispyrazinonaphthalimides antitumor agents.

  Biochemistry 20031014

• Murine DNA cytosine C(5)-methyltransferase: in vitro studies of de novo methylation spreading.

  Biochemical and biophysical research communications 20031010

• Methods for the design and analysis of oligodeoxynucleotide-based DNA (cytosine-5) methyltransferase inhibitors.

  Analytical biochemistry 20031001

• Mammalian DNA (cytosine-5) methyltransferases and their expression.

  Clinical immunology (Orlando, Fla.) 20031001

• Age-related epigenetic changes and the immune system.

  Clinical immunology (Orlando, Fla.) 20031001

• EPR and ENDOR study of crystalline cytosine x HCl doped with 5-methylcytosine. Radiation-induced radical formation and hole transfer.

  Radiation research 20030901

• Procaine is a DNA-demethylating agent with growth-inhibitory effects in human cancer cells.

  Cancer research 20030815

• Heterodimers of bHLH-PAS protein fragments derived from AhR, AhRR, and Arnt prepared by co-expression in Escherichia coli: characterization of their DNA binding activity and preparation of a DNA complex.

  Journal of biochemistry 20030701

• Telomerase expression in normal human fibroblasts stabilizes DNA 5-methylcytosine transferase I.

  The Journal of biological chemistry 20030530

• Expression of various genes is controlled by DNA methylation during mammalian development.

  Journal of cellular biochemistry 20030401

• The relationship between hypomethylation and CpG island methylation in colorectal neoplasia.

  The American journal of pathology 20030401

• Modulation of human nucleotide excision repair by 5-methylcytosines.

  Biochemistry 20030325

• Deamination of 5-methylcytosines within cyclobutane pyrimidine dimers is an important component of UVB mutagenesis.

  The Journal of biological chemistry 20030321

• Sequence context at human single nucleotide polymorphisms: overrepresentation of CpG dinucleotide at polymorphic sites and suppression of variation in CpG islands.

  Journal of molecular biology 20030321

• Substrate specificity of human endonuclease III (hNTH1). Effect of human APE1 on hNTH1 activity.

  The Journal of biological chemistry 20030314

• A potent cell-active allosteric inhibitor of murine DNA cytosine C5 methyltransferase.

  The Journal of biological chemistry 20030307

• The main role of human thymine-DNA glycosylase is removal of thymine produced by deamination of 5-methylcytosine and not removal of ethenocytosine.

  The Journal of biological chemistry 20030307

• Genome-wide epigenetic alterations in cloned bovine fetuses.

  Biology of reproduction 20030301

• A systematic profile of DNA methylation in human cancer cell lines.

  Cancer research 20030301

• Arabidopsis MET1 cytosine methyltransferase mutants.

  Genetics 20030301

• Comparative study of the toxic effects of fumonisin B1 in rat C6 glioma cells and p53-null mouse embryo fibroblasts.

  Toxicology 20030201

• Transient decreases in methylation at 5'-cCGG-3' sequences in potato (Solanum tuberosum L.) meristem DNA during progression of tubers through dormancy precede the resumption of sprout growth.

  Plant molecular biology 20030201

• The epsilon-sarcoglycan gene (SGCE), mutated in myoclonus-dystonia syndrome, is maternally imprinted.

  European journal of human genetics : EJHG 20030201

• Race- and age-dependent alterations in global methylation of DNA in squamous cell carcinoma of the lung (United States).

  Cancer causes & control : CCC 20030201

• Singlet excited-state lifetimes of cytosine derivatives measured by femtosecond transient absorption.

  Photochemistry and photobiology 20030201

• Xeroderma pigmentosum group C protein interacts physically and functionally with thymine DNA glycosylase.

  The EMBO journal 20030102

• DNA demethylation is directly related to tumour progression: evidence in normal, pre-malignant and malignant cells from uterine cervix samples.

  Oncology reports 20030101

• Synthesis and antiviral evaluation of beta-D- and beta-L-pentofuranonucleoside derivatives bearing 5-trifluoromethylcytosine as the base.

  Nucleosides, nucleotides & nucleic acids 20030101

• Nuclear transfer: progress and quandaries.

  Reproductive biology and endocrinology : RB&E 20030101

• The inactive X chromosome in the human female is enriched in 5-methylcytosine to an unusual degree and appears to contain more of this modified nucleotide than the remainder of the genome.

  Journal of genetics 20030101

• Practical uses for ecdysteroids in mammals including humans: an update.

  Journal of insect science (Online) 20030101

• Structural effects of cytosine methylation on DNA sugar pucker studied by FTIR.

  Journal of molecular biology 20021206

• 5-Methylcytosine as a marker for the monitoring of DNA methylation.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20021205

• Parental 5-methylcytosine methylation patterns are stable upon inter-species hybridization of Xiphophorus (Teleostei: Poeciliidae) fish.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20021201

• Absence of global genomic cytosine methylation pattern erasure during medaka (Oryzias latipes) early embryo development.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20021201

• Distribution of 5-methylcytosine residues in 5S rRNA genes in Arabidopsis thaliana and Secale cereale.

  Molecular genetics and genomics : MGG 20021201

• Evaluation of a potential epigenetic biomarker by quantitative methyl-single nucleotide polymorphism analysis.

  Electrophoresis 20021201

• Abrogation of upstream open reading frame-mediated translational control of a plant S-adenosylmethionine decarboxylase results in polyamine disruption and growth perturbations.

  The Journal of biological chemistry 20021115

• Aberrant methylation patterns at the two-cell stage as an indicator of early developmental failure.

  Molecular reproduction and development 20021101

• DNA methylation changes in leukaemia.

  Seminars in cancer biology 20021001

• Mutagenicity of 5-formylcytosine, an oxidation product of 5-methylcytosine, in DNA in mammalian cells.

  Journal of biochemistry 20021001

• Repair of deaminated bases in DNA.

  Free radical biology & medicine 20021001

• Hypomethylation and hypermethylation of DNA in Wilms tumors.

  Oncogene 20020926

• RNA methyltransferases utilize two cysteine residues in the formation of 5-methylcytosine.

  Biochemistry 20020917

• Acyclic nucleoside analogues as novel inhibitors of human mitochondrial thymidine kinase.

  Journal of medicinal chemistry 20020912

• Estradiol receptor potentiates, in vitro, the activity of 5-methylcytosine DNA glycosylase.

  FEBS letters 20020911

• Site-specific discrimination of Cytosine and 5-methylcytosine in duplex DNA by Peptide nucleic acids.

  Journal of the American Chemical Society 20020904

• Specific methylation of the CpG-rich domains in the promoter of the human tissue transglutaminase gene.

  Gene 20020904

• Determination of methylation site of DNA-methyltransferase NlaX by a hybrid method.

  BioTechniques 20020901

• DNA methylation: a profile of methods and applications.

  BioTechniques 20020901

• Germ-line variants in methyl-group metabolism genes and susceptibility to DNA methylation in normal tissues and human primary tumors.

  Cancer research 20020801

• Phase-change related epigenetic and physiological changes in Pinus radiata D. Don.

  Planta 20020801

• Enhanced CpG mutability and tumorigenesis in MBD4-deficient mice.

  Science (New York, N.Y.) 20020719

• DNA sequence recognition by the antitumor drug ditercalinium.

  Biochemistry 20020709

• Inactivation of O6-methylguanine-DNA methyltransferase by promoter CpG island hypermethylation in gastric cancers.

  British journal of cancer 20020617

• Role for DNA methylation in the control of cell type specific maspin expression.

  Nature genetics 20020601

• Cooperation and competition in mismatch repair: very short-patch repair and methyl-directed mismatch repair in Escherichia coli.

  Molecular microbiology 20020601

• Identification and resolution of artifacts in bisulfite sequencing.

  Methods (San Diego, Calif.) 20020601

• Profiling DNA methylation by melting analysis.

  Methods (San Diego, Calif.) 20020601

• Quantitative methylation analysis using methylation-sensitive single-nucleotide primer extension (Ms-SNuPE).

  Methods (San Diego, Calif.) 20020601

• Measurement of genome wide DNA methylation by reversed-phase high-performance liquid chromatography.

  Methods (San Diego, Calif.) 20020601

• Analysis of complex methylation data.

  Methods (San Diego, Calif.) 20020601

• An overview of the analysis of DNA methylation in mammalian genomes.

  Biological chemistry 20020601

• 5-Methyldeoxycytidine monophosphate deaminase and 5-methylcytidyl-DNA deaminase activities are present in human mature sperm cells.

  FEBS letters 20020522

• De novo methylation of MMLV provirus in embryonic stem cells: CpG versus non-CpG methylation.

  Gene 20020501

• Determination of purine and pyrimidine bases in DNA by micellar electrokinetic capillary chromatography with electrochemical detection.

  Journal of chromatography. A 20020419

• Differential patterns of methylation of the IFN-gamma promoter at CpG and non-CpG sites underlie differences in IFN-gamma gene expression between human neonatal and adult CD45RO- T cells.

  Journal of immunology (Baltimore, Md. : 1950) 20020315

• Modification of the human thymine-DNA glycosylase by ubiquitin-like proteins facilitates enzymatic turnover.

  The EMBO journal 20020315

• DNA methylation at promoter regions regulates the timing of gene activation in Xenopus laevis embryos.

  Developmental biology 20020301

• Conformational changes of a benzo[a]pyrene diol epoxide-N(2)-dG adduct induced by a 5'-flanking 5-methyl-substituted cytosine in a (Me)CG double-stranded oligonucleotide sequence context.

  Chemical research in toxicology 20020301

• Charge effects for differentiation of oligodeoxynucleotide isomers containing 8-oxo-dG residues.

  Journal of the American Society for Mass Spectrometry 20020301

• Complex relationships between 5-aza-dC induced DNA demethylation and chromosome compaction at mitosis.

  Chromosoma 20020301

• DNA methylation and the regulation of gene transcription.

  Cellular and molecular life sciences : CMLS 20020201

• DNA hypomethylation and methyltransferase expression in atherosclerotic lesions.

  Vascular medicine (London, England) 20020201

• Dynamic reprogramming of DNA methylation in the early mouse embryo.

  Developmental biology 20020101

• Characterization of the substrate specificity of a human 5-hydroxymethyluracil glycosylase activity.

  Chemical research in toxicology 20020101

• Epigenetic reprogramming in the mammalian embryo: struggle of the clones.

  Genome biology 20020101

• Partial Xp duplication in a girl with dysmorphic features: the change in replication pattern of late-replicating dupX chromosome.

  Clinical genetics 20020101

• Sequence permutations in the molecular evolution of DNA methyltransferases.

  BMC evolutionary biology 20020101

• Methylation and silencing of the retinoic acid receptor-beta 2 gene in cervical cancer.

  BMC cancer 20020101

• Measuring DNA demethylase activity in vitro.

  Methods in molecular biology (Clifton, N.J.) 20020101

• Genomic comparisons among Escherichia coli strains B, K-12, and O157:H7 using IS elements as molecular markers.

  BMC microbiology 20020101

• Signal and noise in bridging PCR.

  BMC biotechnology 20020101

• Quantitative assessment of the use of modified nucleoside triphosphates in expression profiling: differential effects on signal intensities and impacts on expression ratios.

  BMC biotechnology 20020101

• Demethylation of classical satellite 2 and 3 DNA with chromosomal instability in senescent human fibroblasts.

  Experimental gerontology 20020101

• Asymmetric directional mutation pressures in bacteria.

  Genome biology 20020101

• Gene expression patterns vary in clonal cell cultures from Rett syndrome females with eight different MECP2 mutations.

  BMC medical genetics 20020101

• Methylation of a euchromatin-heterochromatin transition region in Arabidopsis thaliana chromosome 5 left arm.

  Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology 20020101

• Overall DNA methylation and chromatin structure of normal and abnormal X chromosomes.

  Cytogenetic and genome research 20020101

• Genome-wide methylation patterns in normal and uniparental early mouse embryos.

  Human molecular genetics 20011215

• DNA methylation patterns in hereditary human cancers mimic sporadic tumorigenesis.

  Human molecular genetics 20011215

• Molecular biology. Methylation talk between histones and DNA.

  Science (New York, N.Y.) 20011207

• DNA methyltransferase 3B mutations linked to the ICF syndrome cause dysregulation of lymphogenesis genes.

  Human molecular genetics 20011201

• DNA from Aspergillus flavus contains 5-methylcytosine.

  FEMS microbiology letters 20011127

• Characterization and overproduction of EcoO109I methyltransferase.

  Bioscience, biotechnology, and biochemistry 20011101

• KG-1 and KG-1a model the p15 CpG island methylation observed in acute myeloid leukemia patients.

  Leukemia research 20011001

• Biochemical characterization of uracil processing activities in the hyperthermophilic archaeon Pyrobaculum aerophilum.

  The Journal of biological chemistry 20010810

• Activation of the maternally preset program of apoptosis by microinjection of 5-aza-2'-deoxycytidine and 5-methyl-2'-deoxycytidine-5'-triphosphate in Xenopus laevis embryos.

  Development, growth & differentiation 20010801

• Altered global methylation of DNA: an epigenetic difference in susceptibility for lung cancer is associated with its progression.

  Human pathology 20010801

• The activity of the murine DNA methyltransferase Dnmt1 is controlled by interaction of the catalytic domain with the N-terminal part of the enzyme leading to an allosteric activation of the enzyme after binding to methylated DNA.

  Journal of molecular biology 20010622

• Genome-wide hypomethylation in hepatocellular carcinogenesis.

  Cancer research 20010515

• Characterization of functional interactions among the Escherichia coli mismatch repair proteins using a bacterial two-hybrid assay.

  Mutation research 20010510

• Extent of CpG methylation is not proportional to the in vivo spontaneous mutation frequency at transgenic loci in Big Blue rodents.

  Mutation research 20010509

• Role of MED1 (MBD4) Gene in DNA repair and human cancer.

  Journal of cellular physiology 20010501

• Status of p53, p21, mdm2, pRb proteins, and DNA methylation in gonocytes of control and gamma-irradiated rats during testicular development.

  Biology of reproduction 20010501

• MECP2 truncating mutations cause histone H4 hyperacetylation in Rett syndrome.

  Human molecular genetics 20010501

• Methylation matters.

  Journal of medical genetics 20010501

• Stability and inheritance of methylation states at PstI sites in Pisum.

  Molecular genetics and genomics : MGG 20010501

• Glucocorticoid-induced DNA demethylation and gene memory during development.

  The EMBO journal 20010417

• Changes in DNA methylation in neoplasia: pathophysiology and therapeutic implications.

  Annals of internal medicine 20010403

• Simultaneous determination of flucytosine and fluorouracil in human plasma by high-performance liquid chromatography.

  Biomedical chromatography : BMC 20010401

• DNA methylation learns to fly.

  Trends in genetics : TIG 20010401

• The role of DNA methyltransferase 1 in growth control.

  Frontiers in bioscience : a journal and virtual library 20010401

• Sequence-specific and methylation-dependent and -independent binding of rice nuclear proteins to a rice tungro bacilliform virus vascular bundle expression element.

  The Journal of biological chemistry 20010126

• Similarities in sunlight-induced mutational spectra of CpG-methylated transgenes and the p53 gene in skin cancer point to an important role of 5-methylcytosine residues in solar UV mutagenesis.

  Journal of molecular biology 20010119

• In-tube DNA methylation profiling by fluorescence melting curve analysis.

  Clinical chemistry 20010101

• Use of DNA molecules substituted with unnatural nucleotides to probe specific drug-DNA interactions.

  Methods in enzymology 20010101

• Thymine DNA glycosylase.

  Progress in nucleic acid research and molecular biology 20010101

• Compaction, stainability and methylation of the late replicating X chromosome in mouse female fibroblasts.

  Cytogenetics and cell genetics 20010101

• Sex chromatin and nucleolar analyses in Rumex acetosa L.

  Protoplasma 20010101

• Discrimination of three mutational events that result in a disruption of the R122 primary autolysis site of the human cationic trypsinogen (PRSS1) by denaturing high performance liquid chromatography.

  BMC genetics 20010101

• Southern analysis using methyl-sensitive restriction enzymes.

  Methods in molecular biology (Clifton, N.J.) 20010101

• Methylation analysis of CpG islands.

  Methods in molecular medicine 20010101

• AZT-induced hypermethylation of human thymidine kinase gene in the absence of total DNA hypermethylation.

  FEBS letters 19961104