55750-53-3 | 6-Maleimidocaproic acid

Packsize	Purity	Availability	Price	Discounted Price
5g	98%	in stock	$13.00	$9.00
10g	98%	in stock	$22.00	$16.00
25g	98%	in stock	$36.00	$26.00
100g	98%	in stock	$115.00	$81.00
500g	98%	in stock	$573.00	$401.00

Description

• Catalog Number: AI52497
• Chemical Name: 6-Maleimidocaproic acid
• CAS Number: 55750-53-3
• Molecular Formula: C10H13NO4
• Molecular Weight: 211.2145
• MDL Number: MFCD00043140
• SMILES: OC(=O)CCCCCN1C(=O)C=CC1=O

Computed Properties

• Complexity: 291
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 15
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 6
• XLogP3: 1.1

Literature

• Tailored PEG for rh-G-CSF analogue site-specific conjugation.

  Bioconjugate chemistry 20090601

• Synthesis and biological evaluation of an albumin-binding prodrug of doxorubicin that is cleaved by prostate-specific antigen (PSA) in a PSA-positive orthotopic prostate carcinoma model (LNCaP).

  International journal of cancer 20080301

• Synthesis, cleavage profile, and antitumor efficacy of an albumin-binding prodrug of methotrexate that is cleaved by plasmin and cathepsin B.

  Archiv der Pharmazie 20070801

• Studies on heterobifunctional cross-linking reagents, 6-maleimidohexanoic acid active esters.

  Chemical & pharmaceutical bulletin 20070401

• Exploiting the substrate tolerance of farnesyltransferase for site-selective protein derivatization.

  Chembiochem : a European journal of chemical biology 20070305

• Development of albumin-binding camptothecin prodrugs using a Peptide positional scanning library.

  Bioconjugate chemistry 20070101

• Development of albumin-binding doxorubicin prodrugs that are cleaved by prostate-specific antigen.

  Archiv der Pharmazie 20051001

• Synthesis and biological activity of water-soluble maleimide derivatives of the anticancer drug carboplatin designed as albumin-binding prodrugs.

  Bioconjugate chemistry 20040101

• Carbohydrate-centered maleimide cluster as a new type of templates for multivalent peptide assembling. synthesis of multivalent HIV-1 gp41 peptides.

  Bioorganic & medicinal chemistry 20030102

• CNS neurons express two distinct plasma membrane electron transport systems implicated in neuronal viability.

  Journal of neurochemistry 20021101

• Design, synthesis, and biochemical evaluation of N-substituted maleimides as inhibitors of prostaglandin endoperoxide synthases.

  Journal of medicinal chemistry 19960412