55750-63-5 | N-Succinimidyl 6-maleimidohexanoate

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$16.00	$11.00
5g	98%	in stock	$31.00	$22.00
10g	98%	in stock	$60.00	$42.00
25g	98%	in stock	$130.00	$91.00
100g	98%	in stock	$418.00	$292.00

Description

• Catalog Number: AB77801
• Chemical Name: N-Succinimidyl 6-maleimidohexanoate
• CAS Number: 55750-63-5
• Molecular Formula: C14H18N2O6
• Molecular Weight: 310.3025
• MDL Number: MFCD00043043
• SMILES: O=C(ON1C(=O)CCC1=O)CCCCCN1C(=O)CCC1=O

Computed Properties

• Complexity: 520
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 22
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 8
• XLogP3: -0.5

Upstream Synthesis Route

N-Succinimidyl 6-Maleimidohexanoate is a versatile compound commonly used in chemical synthesis. This reagent plays a crucial role in various bioconjugation reactions where it is used as a crosslinker to attach molecules together. In particular, N-Succinimidyl 6-Maleimidohexanoate is highly valued in the field of protein chemistry and bioconjugation due to its ability to react specifically with thiol groups on proteins, forming stable thioether linkages.This compound is extensively employed in the modification of proteins for various research and industrial applications. By using N-Succinimidyl 6-Maleimidohexanoate, chemists can selectively label proteins with different functional groups or biomolecules, allowing for the creation of protein conjugates with specific properties or functionalities. Furthermore, the reactivity of N-Succinimidyl 6-Maleimidohexanoate towards thiols makes it a valuable tool in the development of targeted drug delivery systems, diagnostics, and biomaterials.Overall, N-Succinimidyl 6-Maleimidohexanoate enables precise and controllable modifications of proteins, facilitating the advancement of bioconjugation strategies and opening up new opportunities for the design and development of novel bioactive compounds and materials.

Literature

• Functional diversity of endothelin pathways in human lung fibroblasts may be based on structural diversity of the endothelin receptors.

  Biochemistry 20031202