56038-13-2 | Sucralose

Packsize	Purity	Availability	Price	Discounted Price
5g	98%	in stock	$6.00	$4.00
25g	98%	in stock	$18.00	$12.00
100g	98%	in stock	$52.00	$36.00
500g	97%	in stock	$251.00	$176.00

Description

• Catalog Number: AI52570
• Chemical Name: Sucralose
• CAS Number: 56038-13-2
• Molecular Formula: C12H19Cl3O8
• Molecular Weight: 397.6335
• MDL Number: MFCD03648615
• SMILES: ClC[C@H]1O[C@@]([C@H]([C@@H]1O)O)(CCl)O[C@H]1O[C@H](CO)[C@@H]([C@@H]([C@H]1O)O)Cl
• NSC Number: 759272

Computed Properties

• Complexity: 405
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 9
• Heavy Atom Count: 23
• Hydrogen Bond Acceptor Count: 8
• Hydrogen Bond Donor Count: 5
• Rotatable Bond Count: 5
• XLogP3: -1.5

Literature

• Chemotherapy drug thioTEPA exacerbates stress-induced anhedonia and corticosteroid responses but not impairment of hippocampal cell proliferation in adult mice.

  Behavioural brain research 20130101

• Differentiating sources of anthropogenic loading to impaired water bodies utilizing ratios of sucralose and other microconstituents.

  Water research 20121115

• Presence, fate and effects of the intense sweetener sucralose in the aquatic environment.

  The Science of the total environment 20121101

• Investigation of polar organic solvents compatible with Corona Charged Aerosol Detection and their use for the determination of sugars by hydrophilic interaction liquid chromatography.

  Analytica chimica acta 20121031

• Sources of nutrients impacting surface waters in Florida: a review.

  Journal of environmental management 20121030

• Reaction kinetics and efficiencies for the hydroxyl and sulfate radical based oxidation of artificial sweeteners in water.

  The journal of physical chemistry. A 20121011

• Increased small intestinal permeability in ulcerative colitis: rather genetic than environmental and a risk factor for extensive disease?

  Inflammatory bowel diseases 20121001

• Increased intestinal permeability in malnourished patients with liver cirrhosis.

  European journal of clinical nutrition 20121001

• Determination of artificial sweeteners in water samples by solid-phase extraction and liquid chromatography-tandem mass spectrometry.

  Journal of chromatography. A 20120921

• Highly efficient biosynthesis of sucrose-6-acetate with cross-linked aggregates of Lipozyme TL 100 L.

  Journal of biotechnology 20120915

• MSG intake and preference in mice are influenced by prior testing experience.

  Physiology & behavior 20120910

• Sensory characteristics and relative sweetness of tagatose and other sweeteners.

  Journal of food science 20120901

• Organic micropollutants in rivers downstream of the megacity Beijing: sources and mass fluxes in a large-scale wastewater irrigation system.

  Environmental science & technology 20120821

• Transformation of postingestive glucose responses after deletion of sweet taste receptor subunits or gastric bypass surgery.

  American journal of physiology. Endocrinology and metabolism 20120815

• Sucralose revisited: rebuttal of two papers about Splenda safety.

  Regulatory toxicology and pharmacology : RTP 20120801

• Bitter taste inhibiting agents for whey protein hydrolysate and whey protein hydrolysate beverages.

  Journal of food science 20120801

• Active compounds and distinctive sensory features provided by American ginseng (Panax quinquefolius L.) extract in a new functional milk beverage.

  Journal of dairy science 20120801

• Determinants of taste preference and acceptability: quality versus hedonics.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20120718

• Stability considerations of aspartame in the direct analysis of artificial sweeteners in water samples using high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS).

  Chemosphere 20120701

• Artificial sweeteners--a recently recognized class of emerging environmental contaminants: a review.

  Analytical and bioanalytical chemistry 20120701

• The regulation of K- and L-cell activity by GLUT2 and the calcium-sensing receptor CasR in rat small intestine.

  The Journal of physiology 20120615

• Nutrient detection by incretin hormone secreting cells.

  Physiology & behavior 20120606

• Preference for sucralose predicts behavioral responses to sweet and bittersweet tastants.

  Chemical senses 20120601

• Rapid stimulus-bound suppression of intake in response to an intraduodenal nonnutritive sweetener after training with nutritive sugars predicting malaise.

  American journal of physiology. Regulatory, integrative and comparative physiology 20120601

• Overweight and obese boys reduce food intake in response to a glucose drink but fail to increase intake in response to exercise of short duration.

  Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 20120601

• Kinetics of the oxidation of sucralose and related carbohydrates by ferrate(VI).

  Chemosphere 20120501

• Effects of diet soda on gut hormones in youths with diabetes.

  Diabetes care 20120501

• Recombinant expression, in vitro refolding, and biophysical characterization of the N-terminal domain of T1R3 taste receptor.

  Protein expression and purification 20120501

• Position of the Academy of Nutrition and Dietetics: use of nutritive and nonnutritive sweeteners.

  Journal of the Academy of Nutrition and Dietetics 20120501

• Etiology of inflammatory bowel disease: a unified hypothesis.

  World journal of gastroenterology 20120421

• Characterization of oral disintegrating film containing donepezil for Alzheimer disease.

  AAPS PharmSciTech 20120301

• Addition of sucralose enhances the release of satiety hormones in combination with pea protein.

  Molecular nutrition & food research 20120301

• Neurobeachin, a regulator of synaptic protein targeting, is associated with body fat mass and feeding behavior in mice and body-mass index in humans.

  PLoS genetics 20120301

• The 90-day oral toxicity of d-psicose in male Wistar rats.

  Journal of clinical biochemistry and nutrition 20120301

• [What is has the artificial sweeteners in indication the food of our diabetics?].

  La Tunisie medicale 20120301

• [Simultaneous determination of five synthetic sweeteners in food by solid phase extraction-high performance liquid chromatography-evaporative light scattering detection].

  Se pu = Chinese journal of chromatography 20120301

• Maternal ethanol consumption by pregnant guinea pigs causes neurobehavioral deficits and increases ethanol preference in offspring.

  Behavioural pharmacology 20120201

• Sucralose - an ecotoxicological challenger?

  Chemosphere 20120101

• Dietary intake of artificial sweeteners by the Belgian population.

  Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20120101

• A2BR adenosine receptor modulates sweet taste in circumvallate taste buds.

  PloS one 20120101

• Glutamate may be an efferent transmitter that elicits inhibition in mouse taste buds.

  PloS one 20120101

• Toxicities effects of pharmaceutical, olive mill and textile wastewaters before and after degradation by Pseudomonas putida mt-2.

  Cancer cell international 20120101

• Effect of the consumption of a new symbiotic shake on glycemia and cholesterol levels in elderly people with type 2 diabetes mellitus.

  Lipids in health and disease 20120101

• Tachykinins stimulate a subset of mouse taste cells.

  PloS one 20120101

• The insular cortex controls food preferences independently of taste receptor signaling.

  Frontiers in systems neuroscience 20120101

• Nonnutritive, low caloric substitutes for food sugars: clinical implications for addressing the incidence of dental caries and overweight/obesity.

  International journal of dentistry 20120101

• Gastrointestinal microbiota do not significantly contribute to T cell activation or GI inflammation in Ndfip1-cKO mice.

  PloS one 20120101

• Characterization of the modes of binding between human sweet taste receptor and low-molecular-weight sweet compounds.

  PloS one 20120101

• Taste quality and intensity of 100 stimuli as reported by rats: the taste-location association task.

  Frontiers in behavioral neuroscience 20120101

• The content of high-intensity sweeteners in different categories of foods available on the Polish market.

  Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20120101

• Rapid post-oral stimulation of intake and flavor conditioning by glucose and fat in the mouse.

  American journal of physiology. Regulatory, integrative and comparative physiology 20111201

• Leptin regulates the reward value of nutrient.

  Nature neuroscience 20111201

• Short-term consumption of sucralose, a nonnutritive sweetener, is similar to water with regard to select markers of hunger signaling and short-term glucose homeostasis in women.

  Nutrition research (New York, N.Y.) 20111201

• Identification and structure elucidation of a p-phenoxybenzaldehyde in bamboo shoots by HPLC-ESI/MS/MS and NMR.

  Journal of agricultural and food chemistry 20111109

• Television viewing at mealtime reduces caloric compensation in peripubertal, but not postpubertal, girls.

  Pediatric research 20111101

• Intestinal permeability is associated with visceral adiposity in healthy women.

  Obesity (Silver Spring, Md.) 20111101

• Artificial sweetener sucralose in U.S. drinking water systems.

  Environmental science & technology 20111015

• Rats display a robust bimodal preference profile for sucralose.

  Chemical senses 20111001

• What caused the recent worldwide increase of inflammatory bowel disease: should sucralose be added as a suspect?

  Inflammatory bowel diseases 20111001

• Effects of the artificial sweetener sucralose on Daphnia magna and Americamysis bahia survival, growth and reproduction.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20111001

• Is moderate red wine consumption safe in inactive inflammatory bowel disease?

  Digestion 20111001

• The Role of the Sweet Taste Receptor in Enteroendocrine Cells and Pancreatic β-Cells.

  Diabetes & metabolism journal 20111001

• Novel analytical approach to a multi-sugar whole gut permeability assay.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110915

• Splenda® improves tolerance of oral potassium citrate supplementation for prevention of stone formation: results of a randomized double-blind trial.

  Journal of endourology 20110901

• What made Canada become a country with the highest incidence of inflammatory bowel disease: could sucralose be the culprit?

  Canadian journal of gastroenterology = Journal canadien de gastroenterologie 20110901

• 2,3,6,3',4'-Penta-O-acetyl-4,1',6'-tri-chloro-4,1',6'-tride-oxy-sucrose.

  Acta crystallographica. Section E, Structure reports online 20110901

• Oxalate and sucralose absorption in idiopathic calcium oxalate stone formers.

  Urology 20110801

• Role of intestinal circadian genes in alcohol-induced gut leakiness.

  Alcoholism, clinical and experimental research 20110701

• Occurrence and suitability of sucralose as an indicator compound of wastewater loading to surface waters in urbanized regions.

  Water research 20110701

• Irritable bowel syndrome, gut microbiota and probiotics.

  Journal of neurogastroenterology and motility 20110701

• Determination of nine high-intensity sweeteners in various foods by high-performance liquid chromatography with mass spectrometric detection.

  Analytical and bioanalytical chemistry 20110601

• Development of a quantitative high-performance thin-layer chromatographic method for sucralose in sewage effluent, surface water, and drinking water.

  Journal of chromatography. A 20110513

• Effects of carbohydrate sugars and artificial sweeteners on appetite and the secretion of gastrointestinal satiety peptides.

  The British journal of nutrition 20110501

• Nonnutritive sweeteners, fructose, and other aspects of diet.

  Diabetes care 20110501

• Cob(I)alamin reacts with sucralose to afford an alkylcobalamin: relevance to in vivo cobalamin and sucralose interaction.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110401

• Effects of oral ingestion of sucralose on gut hormone response and appetite in healthy normal-weight subjects.

  European journal of clinical nutrition 20110401

• Correlation of six anthropogenic markers in wastewater, surface water, bank filtrate, and soil aquifer treatment.

  Journal of environmental monitoring : JEM 20110401

• Kinetic spectrophotometric methods for the determination of artificial sweetener (sucralose) in tablets.

  Drug testing and analysis 20110401

• The cysteine-rich domain of human T1R3 is necessary for the interaction between human T1R2-T1R3 sweet receptors and a sweet-tasting protein, thaumatin.

  Biochemical and biophysical research communications 20110318

• Diclofenac fast-dissolving film: suppression of bitterness by a taste-sensing system.

  Drug development and industrial pharmacy 20110301

• Bioconcentration of the intense sweetener sucralose in a multitrophic battery of aquatic organisms.

  Environmental toxicology and chemistry 20110301

• Pilot study: alleviation of pain in burning mouth syndrome with topical sucralose.

  Headache 20110301

• 1,2,3,3',4',6'-Hexaacetyl-4,6-O-benzyl-idenesucrose.

  Acta crystallographica. Section E, Structure reports online 20110201

• Study on the synthesis of sucrose-6-acetate catalyzed by fructosyltransferase from Aspergillus oryzae.

  New biotechnology 20110131

• Saccharin and other artificial sweeteners in soils: estimated inputs from agriculture and households, degradation, and leaching to groundwater.

  Environmental science & technology 20110115

• Neonatal exposure to sucralose does not alter biochemical markers of neuronal development or adult behavior.

  Nutrition (Burbank, Los Angeles County, Calif.) 20110101

• Sucralose sweetener in vivo effects on blood constituents radiolabeling, red blood cell morphology and radiopharmaceutical biodistribution in rats.

  Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20110101

• Sensing via intestinal sweet taste pathways.

  Frontiers in neuroscience 20110101

• Acute hepatitis in a woman following excessive ingestion of an energy drink: a case report.

  Journal of medical case reports 20110101

• Effects of GLP-1 and incretin-based therapies on gastrointestinal motor function.

  Experimental diabetes research 20110101

• Exercise-induced splanchnic hypoperfusion results in gut dysfunction in healthy men.

  PloS one 20110101

• Reduced viscosity Barley β-Glucan versus placebo: a randomized controlled trial of the effects on insulin sensitivity for individuals at risk for diabetes mellitus.

  Nutrition & metabolism 20110101

• A multi-nutrient supplement reduced markers of inflammation and improved physical performance in active individuals of middle to older age: a randomized, double-blind, placebo-controlled study.

  Nutrition journal 20110101

• Dietary proteins and food-related reward signals.

  Food & nutrition research 20110101

• Gastroduodenal, intestinal and colonic permeability during anticancer therapy.

  Hepato-gastroenterology 20110101

• Intravascular food reward.

  PloS one 20110101

• Sugar substitutes: Health controversy over perceived benefits.

  Journal of pharmacology & pharmacotherapeutics 20110101

• A systematic review on the effect of sweeteners on glycemic response and clinically relevant outcomes.

  BMC medicine 20110101

• A comparative review study of Sneha Kalpana (Paka) vis-a-vis liposome.

  Ayu 20110101

• Sweet taste signaling and the formation of memories of energy sources.

  Frontiers in systems neuroscience 20110101

• Increased intestinal permeability correlates with sigmoid mucosa alpha-synuclein staining and endotoxin exposure markers in early Parkinson's disease.

  PloS one 20110101

• Effect of a vitamin/mineral supplement on children and adults with autism.

  BMC pediatrics 20110101

• Effects of carbohydrates-BCAAs-caffeine ingestion on performance and neuromuscular function during a 2-h treadmill run: a randomized, double-blind, cross-over placebo-controlled study.

  Journal of the International Society of Sports Nutrition 20110101

• Solid dispersions in the form of electrospun core-sheath nanofibers.

  International journal of nanomedicine 20110101

• Gut T1R3 sweet taste receptors do not mediate sucrose-conditioned flavor preferences in mice.

  American journal of physiology. Regulatory, integrative and comparative physiology 20101201

• Third generation solid dispersions of ferulic acid in electrospun composite nanofibers.

  International journal of pharmaceutics 20101115

• Rational development of taste masked oral liquids guided by an electronic tongue.

  International journal of pharmaceutics 20101115

• The absence of genotoxicity of sucralose.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20101101

• Retention behaviour of some high-intensity sweeteners on different SPE sorbents.

  Talanta 20101015

• Effect of the artificial sweetener, sucralose, on small intestinal glucose absorption in healthy human subjects.

  The British journal of nutrition 20100901

• Implicit media frames: automated analysis of public debate on artificial sweeteners.

  Public understanding of science (Bristol, England) 20100901

• Assessing the palatability of oral rehydration solutions in school-aged children: a randomized crossover trial.

  Archives of pediatrics & adolescent medicine 20100801

• Understanding consumption-related sucralose emissions - A conceptual approach combining substance-flow analysis with sampling analysis.

  The Science of the total environment 20100715

• Diet restriction in migraine, based on IgG against foods: a clinical double-blind, randomised, cross-over trial.

  Cephalalgia : an international journal of headache 20100701

• Analysis of sucralose and other sweeteners in water and beverage samples by liquid chromatography/time-of-flight mass spectrometry.

  Journal of chromatography. A 20100618

• Performance of conventional multi-barrier drinking water treatment plants for the removal of four artificial sweeteners.

  Water research 20100601

• Gain weight by 'going diet?' Artificial sweeteners and the neurobiology of sugar cravings: Neuroscience 2010.

  The Yale journal of biology and medicine 20100601

• Key amino acid residues involved in multi-point binding interactions between brazzein, a sweet protein, and the T1R2-T1R3 human sweet receptor.

  Journal of molecular biology 20100514

• Role of protein concentration and protein-saliva interactions in the astringency of whey proteins at low pH.

  Journal of dairy science 20100501

• Positive allosteric modulators of the human sweet taste receptor enhance sweet taste.

  Proceedings of the National Academy of Sciences of the United States of America 20100309

• Effects of timing, sex, and age on site-specific gastrointestinal permeability testing in children and adults.

  Journal of pediatric gastroenterology and nutrition 20100301

• Application of agonist-receptor modeling to the sweetness synergy between high fructose corn syrup and sucralose, and between high-potency sweeteners.

  Journal of food science 20100301

• Development of taste masked fast disintegrating films of levocetirizine dihydrochloride for oral use.

  Current drug delivery 20100101

• Standards of medical care in diabetes--2010.

  Diabetes care 20100101

• The effects of a pre-workout supplement containing caffeine, creatine, and amino acids during three weeks of high-intensity exercise on aerobic and anaerobic performance.

  Journal of the International Society of Sports Nutrition 20100101

• Inadequate toxicity tests of food additive acesulfame.

  International journal of occupational and environmental health 20100101

• Sugar alcohols, caries incidence, and remineralization of caries lesions: a literature review.

  International journal of dentistry 20100101

• Dysglycemias in pregnancy: from diagnosis to treatment. Brazilian consensus statement.

  Diabetology & metabolic syndrome 20100101

• Chronic consumption of fructose rich soft drinks alters tissue lipids of rats.

  Diabetology & metabolic syndrome 20100101

• Comparative effects of selected non-caffeinated rehydration sports drinks on short-term performance following moderate dehydration.

  Journal of the International Society of Sports Nutrition 20100101

• Design of the xylitol for adult caries trial (X-ACT).

  BMC oral health 20100101

• Colonic permeability is higher in Great Danes compared with smaller breed-dogs.

  Journal of animal physiology and animal nutrition 20091201

• Ingestion of diet soda before a glucose load augments glucagon-like peptide-1 secretion.

  Diabetes care 20091201

• Investigation of organoleptic characteristics in the development of soft chews of calcium carbonate as mineral supplement.

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20091201

• The study on long-term toxicity of d-psicose in rats.

  Journal of clinical biochemistry and nutrition 20091101

• An overview of the safety of sucralose.

  Regulatory toxicology and pharmacology : RTP 20091001

• Expert panel report on a study of Splenda in male rats.

  Regulatory toxicology and pharmacology : RTP 20091001

• Development and formulation of a 0.2% oral solution of midazolam containing gamma-cyclodextrin.

  International journal of pharmaceutics 20090911

• A randomized, double-blind, placebo-controlled trial of rifaximin, a nonabsorbable antibiotic, in the treatment of tropical enteropathy.

  The American journal of gastroenterology 20090901

• Determination of complex polysaccharides by HPAE-PAD in foods: validation using accuracy profile.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090801

• Delineation of the chemomechanosensory regulation of gastrin secretion using pure rodent G cells.

  Gastroenterology 20090701

• Analysis and occurrence of seven artificial sweeteners in German waste water and surface water and in soil aquifer treatment (SAT).

  Analytical and bioanalytical chemistry 20090701

• Medium-chain fatty acids improve cognitive function in intensively treated type 1 diabetic patients and support in vitro synaptic transmission during acute hypoglycemia.

  Diabetes 20090501

• [Sweetened solution intake in albino rats: taste versus calories].

  Psicothema 20090501

• Simultaneous determination of nonnutritive sweeteners in foods by HPLC/ESI-MS.

  Journal of agricultural and food chemistry 20090422

• Diet soda intake and risk of incident metabolic syndrome and type 2 diabetes in the Multi-Ethnic Study of Atherosclerosis (MESA).

  Diabetes care 20090401

• Effect of the artificial sweetener, sucralose, on gastric emptying and incretin hormone release in healthy subjects.

  American journal of physiology. Gastrointestinal and liver physiology 20090401

• Incretin release from gut is acutely enhanced by sugar but not by sweeteners in vivo.

  American journal of physiology. Endocrinology and metabolism 20090301

• Consumption of SC45647 and sucralose by rats selectively bred for high and low saccharin intake.

  Chemical senses 20090301

• Sucralose screening in European surface waters using a solid-phase extraction-liquid chromatography-triple quadrupole mass spectrometry method.

  Journal of chromatography. A 20090213

• Nutrient-dependent secretion of glucose-dependent insulinotropic polypeptide from primary murine K cells.

  Diabetologia 20090201

• Clinical relevance of measuring colonic permeability.

  European journal of clinical investigation 20090201

• An energy supply network of nutrient absorption coordinated by calcium and T1R taste receptors in rat small intestine.

  The Journal of physiology 20090101

• Effect of 2 liquid nutritional supplements for diabetes patients on postprandial glucose, insulin secretion, and insulin sensitivity in healthy individuals.

  JPEN. Journal of parenteral and enteral nutrition 20090101

• Standards of medical care in diabetes--2009.

  Diabetes care 20090101

• Pharmacokinetic characteristics and safety and tolerability of a reformulated azelastine hydrochloride nasal spray in patients with chronic rhinitis.

  Expert opinion on drug metabolism & toxicology 20090101

• Sweet taste receptor expressed in pancreatic beta-cells activates the calcium and cyclic AMP signaling systems and stimulates insulin secretion.

  PloS one 20090101

• Analyses of sweet receptor gene (Tas1r2) and preference for sweet stimuli in species of Carnivora.

  The Journal of heredity 20090101

• Determination of nine intense sweeteners in foodstuffs by high-performance liquid chromatography and evaporative light-scattering detection: interlaboratory study.

  Journal of AOAC International 20090101

• Acidogenic potential of 'sugar-free' cough drops.

  The open dentistry journal 20090101

• Sweet taste signaling functions as a hypothalamic glucose sensor.

  Frontiers in integrative neuroscience 20090101

• Determination of sucralose in soft drinks by high-performance thin-layer chromatography: interlaboratory study.

  Journal of AOAC International 20090101

• Double-blind, placebo-controlled trial of reformulated azelastine nasal spray in patients with seasonal allergic rhinitis.

  American journal of rhinology & allergy 20090101

• Preparation and evaluation of soft gellan gum gel containing paracetamol.

  Indian journal of pharmaceutical sciences 20090101

• Physicochemical Characterization, in vitro Release and Permeation Studies of Respirable Rifampicin-Cyclodextrin Inclusion Complexes.

  Indian journal of pharmaceutical sciences 20090101

• Glucose sensing in L cells: a primary cell study.

  Cell metabolism 20081206

• Clinical trial: effect of active lactic acid bacteria on mucosal barrier function in patients with diarrhoea-predominant irritable bowel syndrome.

  Alimentary pharmacology & therapeutics 20081015

• Functional analysis of LjSUT4, a vacuolar sucrose transporter from Lotus japonicus.

  Plant molecular biology 20081001

• Effects of mouth rinses on color stability of resin composites.

  European journal of dentistry 20081001

• Specific interactions between diphenhydramine and alpha-helical poly(glutamic acid)--a new ion-pairing complex for taste masking and pH-controlled diphenhydramine release.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20080901

• Susceptibility to gut leakiness: a possible mechanism for endotoxaemia in non-alcoholic steatohepatitis.

  Liver international : official journal of the International Association for the Study of the Liver 20080801

• Luminal regulation of normal and neoplastic human EC cell serotonin release is mediated by bile salts, amines, tastants, and olfactants.

  American journal of physiology. Gastrointestinal and liver physiology 20080801

• Artificial sweetener persists in the environment.

  Environmental science & technology 20080501

• Sucrose activates human taste pathways differently from artificial sweetener.

  NeuroImage 20080215

• Sucralose and migraine.

  Headache 20080101

• Xylitol gummy bear snacks: a school-based randomized clinical trial.

  BMC oral health 20080101

• Splenda alters gut microflora and increases intestinal p-glycoprotein and cytochrome p-450 in male rats.

  Journal of toxicology and environmental health. Part A 20080101

• Reducing small intestinal permeability attenuates colitis in the IL10 gene-deficient mouse.

  Gut 20080101

• Allelic variation of the Tas1r3 taste receptor gene selectively affects taste responses to sweeteners: evidence from 129.B6-Tas1r3 congenic mice.

  Physiological genomics 20071219

• Effect of chewing gums containing xylitol or probiotic bacteria on salivary mutans streptococci and lactobacilli.

  Clinical oral investigations 20071201

• Altered intestinal function in patients with chronic heart failure.

  Journal of the American College of Cardiology 20071016

• T1R3 and gustducin in gut sense sugars to regulate expression of Na+-glucose cotransporter 1.

  Proceedings of the National Academy of Sciences of the United States of America 20070918

• Analysis and stability of sucralose in a milk-based confection by a simple planar chromatographic method.

  Journal of agricultural and food chemistry 20070905

• Simultaneous determination of nine intense sweeteners in foodstuffs by high performance liquid chromatography and evaporative light scattering detection--development and single-laboratory validation.

  Journal of chromatography. A 20070720

• Caffeine as a flavor additive in soft-drinks.

  Appetite 20070701

• Sweet taste receptors in rat small intestine stimulate glucose absorption through apical GLUT2.

  The Journal of physiology 20070701

• Migraine triggered by sucralose--a case report.

  Headache 20070301

• Barrier function of the gut and multiple organ dysfunction after cardiac surgery.

  The Journal of international medical research 20070101

• Behavioral genetics and taste.

  BMC neuroscience 20070101

• Metabolic responses to the acute ingestion of two commercially available carbonated beverages: A pilot study.

  Journal of the International Society of Sports Nutrition 20070101

• Acute effects of carprofen and meloxicam on canine gastrointestinal permeability and mucosal absorptive capacity.

  Journal of veterinary internal medicine 20070101

• The erosive potential of some flavoured waters.

  European journal of dentistry 20070101

• Sugarcane ShSUT1: analysis of sucrose transport activity and inhibition by sucralose.

  Plant, cell & environment 20061001

• Popular sweetner sucralose as a migraine trigger.

  Headache 20060901

• Testing needed for acesulfame potassium, an artificial sweetener.

  Environmental health perspectives 20060901

• Resolution of common dietary sugars from probe sugars for test of intestinal permeability using capillary column gas chromatography.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060519

• The intake of intense sweeteners - an update review.

  Food additives and contaminants 20060401

• Food labeling: health claims; dietary noncariogenic carbohydrate sweeteners and dental caries. Final rule.

  Federal register 20060329

• Migraine triggered by sucralose--a case report.

  Headache 20060301

• Consumer acceptability of low-sugar watermelon sweetened with non-calorie sweetener by a Native American community.

  International journal of food sciences and nutrition 20060101

• Soy foods have low glycemic and insulin response indices in normal weight subjects.

  Nutrition journal 20060101

• Artificial sweeteners: no calories...sweet!

  FDA consumer 20060101

• Experimental design-based development and single laboratory validation of a capillary zone electrophoresis method for the determination of the artificial sweetener sucralose in food matrices.

  Analytical and bioanalytical chemistry 20050701

• [Analysis of nine kinds of sweeteners in foods by LC/MS].

  Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20050601

• A simple method for the analysis of urinary sucralose for use in tests of intestinal permeability.

  Annals of clinical biochemistry 20050501

• Artificial sweeteners--do they bear a carcinogenic risk?

  Annals of oncology : official journal of the European Society for Medical Oncology 20041001

• Evaluation of a triple sugar test of colonic permeability in humans.

  Acta physiologica Scandinavica 20041001

• Determination of sucralose in Splenda and a sugar-free beverage using high-performance anion-exchange chromatography with pulsed amperometric detection.

  Journal of agricultural and food chemistry 20040714

• Oral zinc sulfate solutions inhibit sweet taste perception.

  Chemical senses 20040701

• Female rats show a bimodal preference response to the artificial sweetener sucralose.

  Chemical senses 20040701

• Acetaminophen-containing chewable tablets with suppressed bitterness and improved oral feeling.

  International journal of pharmaceutics 20040618

• Position of the American Dietetic Association: use of nutritive and nonnutritive sweeteners.

  Journal of the American Dietetic Association 20040201

• Lack of effect of sucralose on glucose homeostasis in subjects with type 2 diabetes.

  Journal of the American Dietetic Association 20031201

• Long-term food consumption and body weight changes in neotame safety studies are consistent with the allometric relationship observed for other sweeteners and during dietary restrictions.

  Regulatory toxicology and pharmacology : RTP 20031001

• Determination of the artificial sweetener Sucralose by capillary electrophoresis.

  Food additives and contaminants 20030601

• In vivo influence of nicotine on human basal and NSAID-induced gut barrier function.

  Scandinavian journal of gastroenterology 20030401

• Gas chromatographic method for detection of urinary sucralose: application to the assessment of intestinal permeability.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030125

• Determination of acesulfame and sucralose in oral electrolyte maintenance solution by liquid chromatography.

  Journal of AOAC International 20030101

• Sweeteners and beta-glucans improve metabolic and anthropometrics variables in well controlled type 2 diabetic patients.

  American journal of therapeutics 20030101

• 4,1',6'-Trichloro-4,1',6'-trideoxysucrose monohydrate.

  Acta crystallographica. Section C, Crystal structure communications 20021201

• [Determination of sucralose in foods by liquid chromatography/tandem mass spectrometry].

  Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20021001

• [Determination of sucralose in foods by HPLC using pre-column derivatization].

  Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20021001

• The comet assay with 8 mouse organs: results with 39 currently used food additives.

  Mutation research 20020826

• Dental considerations in sucralose use.

  The Journal of clinical dentistry 20020101

• Acute gastrointestinal permeability responses to different non-steroidal anti-inflammatory drugs.

  Gut 20011101

• Two halodeoxy sucrose analogues.

  Acta crystallographica. Section C, Crystal structure communications 20011101

• Sweetener preference of C57BL/6ByJ and 129P3/J mice.

  Chemical senses 20010901

• Whole nerve chorda tympani responses to sweeteners in C57BL/6ByJ and 129P3/J mice.

  Chemical senses 20010901

• [Determination of sucralose in foods by anion-exchange chromatography and reverse-phase chromatography].

  Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20010401

• [Determination of sucralose in foods by HPLC].

  Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20010401